Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Kaleab Moges Tesfaye
ID: UNCST-2025-R019103
Congenital Central Nervous System(CNS) and non CNS Anomalies in Children at Cure Children’s Hospital of Uganda
REFNo: HS7204ES

1.2.1 Primary Objective To describe the congenital CNS and non-CNS anomalies in children treated at CCHU from July 2025 to July 2027 1.2.2 Specific Objectives 1. To determine the burden of congenital CNS anomalies in children treated at CCHU. 2. To describe the epidemiology of congenital CNS anomalies in children treated at CCHU. 3. To describe the common congenital non-CNS anomalies in children with congenital CNS anomalies treated at CCHU. 4. To create a pictorial-clinical illustrative album of the congenital anomalies in children treated at CCHU.
Ethiopia 2026-04-10 17:49:46 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon Peter Okiror
ID: UNCST-2025-R022830
Building Artificial Intelligence Models for predicting TB risk among HIV/AIDS patients using routine clinical data at the Joint Clinical Research Centre, Kampala-Uganda
REFNo: HS7054ES

1. To assess the feasibility of applying AI-driven TB risk prediction tools at the Joint Clinical Research Centre. 2. To develop an AI-based predictive model for predicting TB risk among HIV/AIDS patients using routinely collected patient data. 3. To evaluate the performance of the developed models in predicting TB risk among HIV/AIDS patients.
Uganda 2026-04-10 17:48:29 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Sanya Donald
ID: UNCST-2025-R016737
FAMILY PLANNING SERVICES UTILIZATION AND HEALTH RELATED QUALITY OF LIFE IN UGANDA: A CASE OF SELF-SETTLED URBAN REFUGEE AND MIGRANT WOMEN IN WEST NILE SUB-REGION.
REFNo: SS4707ES

i. To examine the impact of access to FPS on HRQoL among self-settled urban refugee and migrant women in Uganda, West Nile Sub-Region.
ii. To analyze the influence of availability of FPS on HRQoL among self-settled urban refugee and migrant women in Uganda, West Nile Sub-Region.
iii. To assess the casual association between FPS education (knowledge, information & awareness) and HRQoL among self-settled urban refugee and migrant women in Uganda, West Nile Sub-Region;
iv. To evaluate the moderating effect of patient factors on FPS and HRQoL among self-settled urban refugee and migrant women in Uganda, West Nile Sub-Region.

Uganda 2026-04-10 17:47:19 2029-04-10 Social Science and Humanities Non-Clinical Trial Degree Award
Onesmus Kamacooko
ID: UNCST-2023-R005897
Caregiver Mental Health, Family Structure, and Positive Parenting:Evidence from the Uganda Parenting for Respectability Program
REFNo: HS6902ES

i. To synthesize evidence on the effectiveness of parenting interventions in enhancing positive parenting practices among multiple caregivers of children aged 0–17 years in Sub-Saharan Africa through a systematic review. ii. To determine the factors associated with depression and anxiety among parents and caregivers of children aged 0-17 years in Uganda. iii. To investigate the longitudinal relationship between caregiver mental health and positive parenting practices over a 12-month follow-up period. iv. To examine the moderating role of family structure in the mediation relationship between intervention effects, caregiver mental health, and positive parenting practices.
Uganda 2026-04-10 17:39:00 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
REDUCING TB MORTALITY DURING AND AFTER TREATMENT THROUGH SCREENING FOR KIDNEY DYSFUNCTION AND IMPLEMENTATION OF A MORTALITY RISK PREDICTION SCORE IN UGANDA
REFNo: HS7321ES

TO REDUCE TB MORTALITY DURING AND AFTER TREATMENT THROUGH SCREENING FOR KIDNEY DYSFUNCTION AND IMPLEMENTATION OF A MORTALITY RISK PREDICTION SCORE IN UGANDA,2. To explore patients’ views on the provision of nutritional support (meals) during TB care and its influence on adherence and recovery.(secondary),1. To explore healthcare workers’ perspectives on the ease of use and acceptability of point-of-care (POC) creatinine testing in TB care (Secondary),4. To determine one-year outcomes among patients admitted with TB and kidney disease. ,3. To introduce bedside point-of-care (POC) creatinine testing and assess the agreement between POC and laboratory-based creatinine tests in evaluating kidney function among adults admitted with TB,2. To revise the PROS score to include the optimal serum creatinine cut-off as a component and determine the accuracy of the revised score to predict TB mortality. ,To determine the optimal serum creatinine cut-off that predicts mortality among patients admitted with TB in Uganda. ,
Uganda 2026-04-10 17:37:08 2029-04-10 Medical and Health Sciences Non-degree Award
KIZZA GERALD
ID: UNCST-2021-R012792
An mHealth-Enabled Social Support Framework to Improve Anti-Diabetes Medication Adherence among Type 2 Diabetes Patients with HIV in Uganda
REFNo: SIR624ES

1. To develop an initial context specific implementation framework for utilizing a mobile phone–enabled social support intervention to enhance anti-diabetes medication adherence among type 2 diabetes patients living with HIV/AIDS in Uganda.

2. To co-design and co-develop an mHealth-enabled social support intervention for medication adherence among Type 2 diabetes patients living with HIV, drawing from the developed implementation framework.

3. To implement the developed intervention and assess its implementation outcomes guided by Proctor framework.

4. To explore the preliminary impact of the intervention on anti-diabetes medication adherence and glycaemic control among participants.

5. To develop an evidence based implementation framework (based on above findings) for utilizing a mobile phone–enabled social support intervention to enhance anti-diabetes medication adherence.

Uganda 2026-04-10 17:29:34 2029-04-10 Engineering and Technology Non-Clinical Trial Degree Award
ANDREW ACOBI
ID:
KNOWLEDGE, SKILLS, SELF-EFFICACY ON ADOPTION OF RESEARCH EVIDENCE IN PRACTICE AMONG NURSES AT LIRA REGIONAL REFERRAL HOSPITAL, LIRA, UGANDA.
REFNo: HS6844ES

Main Objective
To explore knowledge, skills, and self-efficacy on adopting research evidence in practice among nurses at Lira Regional Referral Hospital (LRRH), Lira City, Northern Uganda.
Specific Objectives or Core Objectives
1. To evaluate level of knowledge on the adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.
2. To assess level of skills on the adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.
3. To evaluate self-efficacy-related adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.

4. To analyze the relationship between knowledge and adoption of research evidence in practice among nurses at LRRH, Lira, Uganda


Uganda 2026-04-10 17:28:22 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Richard Katuramu
ID: UNCST-2022-R011266
Investigating the Consequences of USAID's suspension of HIV/AIDS Assistance in Tanzania and Uganda: A Multi-Stakeholder Qualitative Study in Uganda and Tanzania
REFNo: HS6630ES

1. To identify list of organizations/institutions previously funded by the USAID to implement different HIV/AIDS services
2. To explore the perception of the different stakeholders on the suspension of USAID funds for HIV/AIDS activities
3. To examine the short term strategies employed by the stakeholders to mitigate the impact of the suspension of USAID funds for HIV/AIDS activities
4. To explore the projected long-term consequences of this funding loss on the HIV/AIDS workforce, program delivery, research and sustainability
5. To assess the different reprioritization strategies and resource allocation in response to the reduced external assistance
6. To explore the different lessons from past funding disruptions and how they can be applied to improve future health system resilience
7. To examine the different roles, if any, do the stakeholders expect from alternative external donors like China

Uganda 2026-04-10 17:03:11 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CAROLINE KYOSIIMA MWEBESA
ID: UNCST-2026-R023538
Baseline and Endline Evaluation of Women's Economic Empowerment and Female Financial Health in Eastern Uganda (Kaliro and Namutumba Districts)
REFNo: SS5052ES

Objective 1 – Baseline documentation: To establish comprehensive baseline conditions (pre-intervention) regarding women's demographic characteristics, livelihood structures, economic activities and income sources, financial service access and financial behaviors, financial knowledge and digital literacy, household economic decision-making participation, gender relations and intra-household dynamics, and experiences of economic empowerment and disempowerment across both intervention and comparison groups in Kaliro and Namutumba districts. Objective 2 – Impact quantification: To measure the impact of WomenSave programming on women's financial inclusion outcomes (financial service access and productive usage), savings behaviors, economic income and diversification, and household economic decision-making participation over six-month and twelve-month periods when compared to similarly-situated a non-beneficiary comparison group. Objective 3: Mechanism exploration: To qualitatively examine the mechanisms through which WomenSave programming generates economic empowerment outcomes, including individual-level pathways, household-level pathways, and community-level pathways. Objective 4: Implementation and context factors: To document implementation realities, institutional coordination mechanisms, contextual enablers and barriers, and sustainability factors associated with WomenSave programming integration within PDM structures for program improvement, replication, and scaling.
Uganda 2026-04-10 16:52:20 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sandra Asizu
ID: UNCST-2026-R024434
BASELINE SURVEY FOR THE COLLECTIVE ACTION FOR DISABILITY RIGHTS PROGRAMME
REFNo: SS5049ES

I.Provide quantitative and qualitative baseline values for the programme’s outcome and impact indicators.
II.Assess the inclusivity and accessibility of education, health, economic, and social systems for persons with disabilities (PWDs).
III.Evaluate the institutional capacity and operational effectiveness of Organizations of Persons with Disabilities (OPDs).
IV.Inform programme implementation strategies, adaptive management, and subsequent endline evaluations.
Uganda 2026-04-10 16:26:42 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
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