Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Lydia  Kabiri Watsemwa
ID: UNCST-2020-R014567
 Exploring the rationale for an integrated preventive approach to child health in Uganda: Perspectives from families, health care givers and non-health stakeholders
REFNo: HS3931ES

To understand challenges, opportunities, and possible improvements in the current system for preventive child health care in Uganda;

To explore opportunities, barriers, and facilitating factors for creating and implementing a future permanent system for preventive child health, suitable for multisectoral collaboration;

To understand how caregivers currently identifies early signs of illness and developmental delay among young children;

To understand how caregivers and other stakeholders view the possibility for improved knowledge of early signs of illness as well as early screening for and identification of developmental delay and disability among young children.

Uganda 2024-06-05 17:23:17 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zenah Nantumbwe
ID:
A Mental Health Literacy intervention for adolescents in secondary school in Uganda: Implementation and evaluation of “The Wellness Project”
REFNo: HS4071ES

To examine if The Wellness Project intervention has a positive impact on MH care referral system and explore acceptability of MHL intervention program among adolescents and key health contacts. ,To investigate if mental health literacy psychoeducational program will increase mental health - illness knowledge, reduce stigma attitudes towards mental illness and increase help seeking knowledge and intentions among adolescents. ,To access the mental health-illness knowledge, stigma attitudes towards mental illness, help seeking behaviour and school MH care of adolescents in secondary school.,
 Uganda 2024-06-05 17:21:06 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Dennis Kalibbala
ID:
Effectiveness and implementation of HIV self-testing distribution through the Young People and Adolescents Peer Support (YAPS) model in Uganda
REFNo: HS4089ES

3. To explore the effectiveness of HIVST through the YAPS model on linkage to care and treatment outcomes among those who test positive,2. To assess the acceptability and feasibility of HIVST distribution through the YAPS model among young people and adolescents in Uganda.,1. To identify the factors that influence the implementation of HIVST through the YAPS model.,To determine implementation and effectiveness of HIV self-testing through the Young People and Adolescents Peer Support (YAPS) model in Uganda,
 Uganda 2024-06-05 17:19:50 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Aber
ID:
Assessing the effect of Climatic Variables on the Prevalence of Malaria and Meningitis, and Health Worker Perceptions of Climate Change Health Impacts in Northern Uganda.
REFNo: HS3706ES

1. To describe the trends in climate variability, malaria and meningitis prevalence between January 1, 2000, to December 31, 2020, within the districts of Amuru, Gulu, Nwoya, Omoro, and Gulu City.

2. To assess the effect of climatic variables (precipitation, temperature, humidity) on the prevalence of malaria and meningitis between January 1, 2000, to December 31, 2020, within the districts of Amuru, Gulu, Nwoya, Omoro, and Gulu City.

3. To explore the perceptions of primary healthcare professionals (HCP) and district managers in the districts of Amuru, Gulu, Nwoya, Omoro, and Gulu City regarding the impact of climate variability on malaria and meningitis prevalence, as well as explore potential adaptation initiatives to mitigate its effects on the health of populations.

 Uganda 2024-06-05 17:17:56 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kevin Komakech
ID: UNCST-2023-R005979
 Evaluation of Point-of-Care Triage Tests to Aid in Tuberculosis Diagnosis
REFNo: HS4153ES

4. To evaluate the effect of sputum microbiome on the diagnostic performance of selected point of care TB triage test among presumptive TB patients,3. To determine the cost effectiveness of using a point of care TB triage test among presumptive TB patients,2. To determine the diagnostic performance (sensitivity, specificity, positive and negative predictive value) of different point of care TB triage test among presumptive TB patients in a single study ,1. To evaluate the performance of point of care triage tests for pulmonary tuberculosis through a systematic review and meta-analysis ,
 Uganda 2024-06-05 17:16:53 2027-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Contribution of Mobile TB Clinic Fitted with Digital X-ray, CAD and Xpert MTB/RIF/Ultra on same day TB diagnosis and treatment initiation in Uganda.
REFNo: HS3797ES

General Objective
The goal of the study is to assess the usefulness of portable X-ray, CAD and GeneXpert fitted on Mobile TB clinic in enhancing TB detection and initiation of treatment among high risk patients in Uganda.

Specific Objectives
1. To determine the uptake of “enhanced” mobile TB clinic services using targeted active case finding outreaches/activities among the high-risk communities in Uganda.
2. To determine the operational feasibility and cost effectiveness of mobile TB clinics to conducting same day TB screening, diagnosis and treatment initiation.
3. To evaluate the diagnostic performance of CAD4TB using Xpert MTB/Rif ultra as the reference standard.

 Uganda 2024-06-05 17:15:45 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Onep George
ID:
DEVELOPMENT OF A DOWNDRAFT GASIFIER USING BIOMASS GASIFICATION PROCESS FOR POWERING A COMMERCIAL FEED MILL
REFNo: SIR334ES

iv. To evaluate the performance of the downdraft biomass gasifier prototypes in terms of quality of the syngas and thermal efficiency under practical operating conditions. ,iii. To optimize process parameters of equivalent ratio, moisture content and reaction temperature to produce syngas with tar content less that 0.1 g/m3 and carbon dioxide percentage less than 5%,ii. To design and fabricate a downdraft gasifier prototype with a thermal power output of 5KW, Specific Gasification Rate of 2000 m3/m2hr, and able to achieve thermal efficiency of 60%.,i. To characterize groundnut shells and pine wood chippings in order to determine their appropriateness for gasification basing on their calorific value, ash content, fixed carbon, physical features and presence of contaminants.,The aim of this research is to develop a downdraft biomass gasifier for powering a mill for commercial production of animal feeds,
 Uganda 2024-06-05 17:13:40 2027-06-05 Engineering and Technology Non-Clinical Trial Degree Award
Santo Ocii
ID:
Management of students' discipline in the post corporal punishment era in Uganda secondary schools - Northern Uganda
REFNo: SS2471ES

4- To assess the extent to which school’s environment shapes the discipline of students in a school that have demonstrated good practice of discipline in the post corporal punishment era.,3- To provide a description of how head teachers and board of governors support teachers in managing discipline in post corporal punishment era.,2- To examine the disciplinary measures and support used by teachers in managing students’ discipline in the post corporal punishment era.,1- To explore the students’ perspective on the management of school discipline in the post corporal punishment era,The purpose of this study is to understand better ways of managing students’ discipline without using corporal punishment by studying good practices from schools that are exemplary in discipline management that can be copied by other schools still using corporal punishment,
 Uganda 2024-06-05 17:12:19 2027-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
ANTHONY NUWA
ID: UNCST-2022-R011102
 Host Immune dynamics following seasonal malaria chemoprevention in African children
REFNo: HS4350ES

Main Objective
1. To understand the dynamics of host immunity in settings implementing seasonal malaria chemoprevention.
Specific Objectives
1. To comprehensively profile antibody immune responses in individuals before and after single and multiple rounds of SMC.
2. To comprehensively profile the innate and adaptive cellular immune response in individuals living in an area with sustained SMC.
 Uganda 2024-06-05 17:10:29 2027-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olive  Kabaguma
ID: UNCST-2023-R005849
 PSYCHOSOCIAL FACTORS AND WELLNESS OF MIDLIFE RELIGIOUS SISTERS IN UGANDA
REFNo: SS2503ES

To establish the association between psychosocial factors and wellness among religious sisters in Uganda.,
 Uganda 2024-06-05 17:03:18 2027-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rachel McMullan
ID:
Tackling Antimicrobial Resistance Through Professional Learning: Open Societal Challenge
REFNo: SS2650ES

Aim: To synthesise knowledge around the work practices and behaviours required for effective antimicrobial stewardship and identify which of these could be strengthened by professional learning programmes and training. Objectives: 1. To describe health professionals’ practices and behaviours around antibiotics and related tools, processes, networks and challenges 2. To understand the impacts of AMS-related change on health professionals’ practices and behaviours in the work place 3. To identify how health professionals engage with learning opportunities for AMS/AMR, and associated knowledge gaps 4. To identify the AMS-related behaviour(s) in need of change that could be supported in a future intervention 5. To assess current antimicrobial prescribing practices in healthcare facilities across Eastern Uganda.
 UK 2024-06-04 7:28:02 2027-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 Adaptation and Piloting of the Parenting for Respectability Programme for Hybrid Disability Inclusive Parenting Study; Feasibility, Process, and Lessons from Uganda
REFNo: HS4054ES

Research objective
The study aims to adapt and test the feasibility and acceptability of the PfR programme for parents with disabilities and parents of children with disabilities.

Specific objectives
i.To assess the extent to which existing national policies respond to the needs of parents and children with disabilities
ii.Qualitatively assess knowledge, attitudes and practices on parenting among parents and children with disabilities
iii.To adapt and pilot the existing Parenting for Respectability programme manual for facilitator-assisted WhatsApp group-based delivery in order to assess accessibility, functionality, inclusivity, and examine facilitating and hindering factors around disability inclusive parenting

Uganda 2024-05-31 18:34:28 2027-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
 Title:Evaluating the Burden of Post-Tuberculosis Morbidity Among TB Disease Survivors in Uganda: A Pilot Feasibility Study
REFNo: HS4037ES

The objective of the proposal is to conduct a pilot feasibility study on post-tuberculosis (TB) survivors as a preliminary step in planning for a future large cohort study to broadly evaluate post-TB morbidity. ,
 Uganda 2024-05-31 18:33:32 2027-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phiona Arineitwe
ID:
Institutional Support and Teacher Competence Mediated by Organisational Learning in Government-Aided Secondary Schools in South Western Uganda, Uganda.
REFNo: SS2518ES

1. To investigate the influence of institutional support on teacher competence in government-aided secondary schools in South Western Uganda.
2. To establish the influence of institutional support on organisational learning in government-aided secondary schools in South Western Uganda.
3. To determine the influence of organisational learning on teacher competence in government-aided secondary schools in South Western Uganda.
4. To test the mediating effect of organisational learning on the influence of institutional support on teacher competence in government-aided secondary schools in South Western Uganda

 Uganda 2024-05-31 18:31:51 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Herbert Kiwalya
ID: UNCST-2024-R004872
 Electronic healthcare registries: An evaluation of current practices, stakeholder perceptions and implementation effectiveness.
REFNo: HS4359ES

Evaluate the effectiveness and usability of an electronic registry implemented to enhance the availability and accessibility of patient-level data for quality improvement and decision-making.,Describe the implementation requirements for an electronic healthcare registry in Uganda and identify barriers that may be encountered during its’ setup and utilisation.,Assess the current practices and challenges in documenting, accessing and using patient-level, registry-based healthcare data in eastern Uganda.,Describe stakeholder perceptions of electronic healthcare registries to facilitate quality improvement, clinical benchmarking and research at local, regional, national and international levels of the healthcare system in Uganda, Ethiopia, and South Africa.,We aim to understand current views of stakeholders in three African countries about the use of electronic healthcare registries. This will include developing a detailed understanding of the local context from eastern Uganda. Following implementation of an integrated electronic registry to support quality improvement work we will conduct a process evaluation that will allow us to reflect on the effectiveness of our registry in this setting.,
 Uganda 2024-05-31 18:30:37 2027-05-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Alice Endra Ezuru
ID:
Access and Application of digital technologies among fishing communities in Uganda: a case of Lake Victoria community
REFNo: SS2677ES

i). To examine the information needs (personal, trade, health, fishing inputs, technology) of the fishing communities of Lake Victoria, Uganda.
ii). To establish the digital technologies used in information access by the fishing communities of Lake Victoria, Uganda.
iii). To determine the access and application of digital technologies in information dissemination within the fishing communities and managers of Lake Victoria in Uganda.
v). To examine challenges (if any) in access and application of digital technologies among the fishing communities of Lake Victoria in Uganda.

 Uganda 2024-05-31 18:29:42 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Ali Kudamba
ID:
Anticancer activity and safety of Rhoicissus tridentata (L.f) Wild & R.B. Drumm. as used in the treatment of prostate cancer in the Elgon sub-region, Uganda
REFNo: HS3007ES

To determine the effect of aqueous, methanol, & total crude of Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on the antiproliferative activity (% growth inhibition or cell viability) of the prostate cancer cell line,To assess the effect of aqueous, methanol, and total crude extracts from Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on the apoptotic index of the prostate cancer cell line. ,To assess the effect of methanol, aqueous, and total crude extracts Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on sub-acute toxicity in Wistar albino rats. ,To assess the effect of methanol, aqueous, and total crude extracts Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. on acute toxicity in female Wistar albino mice. ,To determine the phytochemical compositions of aqueous and methanol extracts of Rhoicissus tridentata (Lf.) Wild & R.B. Drumm. harvested from the volcanic soils of mountain Elgon slopes.,To describe the medicinal plants used in the treatment of cancers with emphasis on prostate cancer,The study is aimed at assessing the anticancer activity and safety of Rhoicissus tridentata (L.f.) Wild & R.B. Drumm used in the treatment of prostate cancer in the Elgon sub-region. ,
 Uganda 2024-05-31 18:28:36 2027-05-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Lauren Wolf
ID:
The Spatial Ecology of the Red Colobus Monkeys
REFNo: NS808ES

The overall goal of this project is to comprehensively understand the ecological and social determinants that influence the spatial behavior of the Ashy Red Colobus Monkey.
USA 2024-05-31 18:27:17 2027-05-31 Natural Sciences Non-Clinical Trial Degree Award
SHANNA NANTUME AGNES
ID: UNCST-2024-R004915
 CHILD MALTREATMENT,SOCIAL SUPPORT AND PSYCHOLOGICAL WELL-BEING AMONG ADOLESCENTS IN NAGURU REMAND HOME
REFNo: SS2642ES

1. To identify the best predictor of psychological well-being among adolescents in a remand home. 2. To determine the relationship between child maltreatment and social support among these adolescents. 3. To assess the relationship between social support and psychological well-being among adolescents. 4. To examine the relationship between child maltreatment and psychological well-being among adolescents.
 Uganda 2024-05-31 18:26:39 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Karen Setty Elizabeth
ID:
Tracking the Ripple Effects of Water Quality Information Sharing among Household Consumers, Water Managers, and Local Officials
REFNo: SS2609ES

1. Characterize actual information uses and applications that might affect water management practices and policies. - Follow up with participants through surveys and qualitative interviews after each information-sharing event. - Individually deliver a series of water quality reports containing solution-oriented messages. - Evaluate the uses and impact of water quality data among local government, water management, and household decision-makers. 2. Tailor a water quality information delivery intervention through a user-centered design process. - Establish good practices for water quality information sharing in small water supply systems in low-resource settings.
 USA 2024-05-31 18:25:09 2027-05-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
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