Winnie Muyindike R
ID: UNCST-2021-R013558
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HIV-1 subtype-specific drug resistance in patients failing dolutegravir-based first-line, second-line or third-line regimens: multiregional study (DTG resist study)”
REFNo: HS2435ES
Main Objective
1.To determine the patterns and spectrum of InSTI DRMs in adults and adolescents with virologic failure on DTG-based ART by ART regimen and HIV-1 subtype.
2. To identify risk factors for virologic failure, InSTI DRMs, and InSTI drug resistance in adolescents and adults on DTG-based ART, including drug, host and health system factors.
Specific Objectives
1a) To identify the prevalence of InSTI DRMs at the time of virologic failure.
1b) To compare the prevalence of InSTI DRMs at the time of virologic failure between HIV-1 subtypes and treatment contexts.
2a) To identify risk factors for Virologic Failure
2b) To identify risk factors for Drug Resistance Mutations.
3. To investigate correlations between novel resistance genotypes and phenotypic DTG resistance across HIV-1 subtypes.
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Uganda |
2022-10-05 15:04:09 |
2025-10-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Jefferson Mtongolo Mwaisaka
ID: UNCST-2022-R010784
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An impact evaluation study of the Delivering Resilient Enterprises and Market Systems (DREAMS) project targeting refugees and host communities in Bidi Bidi and Rhino Camps, West Nile Uganda
REFNo: SS1445ES
To determine the cost-effectiveness of DREAMS compared to the status quo,To assess if there's any suggestive evidence that outcomes are substantially different for households that participate in both graduation and MSD programs vs households that only participate in graduation programs,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in host communities in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in a refugee camp in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS (poverty graduation + indirect MSD + direct market support) on livelihoods, social cohesion, and perceived wellbeing of vulnerable refugee and host community households in Uganda’s West Nile refugee settlements,
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Kenya |
2022-10-05 12:26:04 |
2025-10-05 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Samson Omongot
ID:
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Validation of air pollution particulate matter measurements and characterization of the source apportionment using chemical speciation in urban Kampala.
REFNo: NS416ES
ii) To determine sources of pollutants using filter sampler Gravimetric Method in 12 months at Makindye & Kawempe divisions of Kampala district.,Specific objectives for Aim 2 i) To determine chemical composition of pollutants using filter sampler Gravimetric method in 12 months at Makindye & kawempe divisions of Kampala district,Aim 2 General Objective To determine the pollutants’ components in particulate matter (PM) and establish their specific sources using filter sampler gravimetric method in computer-based model Positive Matrix Factorization (PMF),iii) To assess the correlation of PM2.5 measurements between AirQo twin plan tower Monitor and filter sampler Gravimetric method,ii) To determine the correlation of the PM2.5 measurements between the filter sampler Gravimetric method, and the internationally standardized Kampala BAM ,Specific Objectives for Aim 1 i) To determine the correlation of PM2.5 measurements between AirQo twin plan tower monitors and the internationally standardized Kampala BAM ,Aim 1 General Objective To examine the correlation of ambient air pollution PM2.5 measurements between AirQo twin Plan tower Monitor (TPTM), filter sampler Gravimetric method and US Embassy Beta Attenuation Monitor (BAM).,
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Uganda |
2022-10-05 12:24:41 |
2025-10-05 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Wilfred Arubaku
ID:
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Role of Physiotherapy in Ugandan Neurosurgical Transitional Care
REFNo: HS2369ES
3. To examine the knowledge, attitudes and beliefs of medical providers, rehabilitation providers, patients, and caregivers as to the inclusion of rehabilitation services in discharge practice.,2. To describe the experiences of discharge practice from the perspectives of medical providers, rehabilitation providers, patients, and caregivers.,1. To describe the process steps that are happening during discharge practice for medical providers, rehabilitation providers, patients, and caregivers.,This study aims to examine and understand the involvement of current rehabilitation professionals in discharge practices TBI and SCI patients in acute hospital settings. Results from this study will inform the development of care transition interventions that increase patient access and utilization of rehabilitation services to improve quality of life.,
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Uganda |
2022-10-05 12:23:17 |
2025-10-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Waiswa Peter
ID: UNCST-2020-R014921
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Reducing neonatal and maternal mortality by rapid detection of sepsis inresource-limited environments
REFNo: HS2439ES
To assess the perception of health workers on the use of the test for detection of neonatal sepsis in their units.
To compare mortality rate within groups of neonates and mothers in whom SAA is detected and those in whom SAA was not detected in a resource-limited environment.
To characterise the clinical presentation and outcome of sepsis in all participants and information on treatment and duration.
To determine the detection of SAA following serial tests and treatment for neonates and mothers suspected to have sepsis.
To describe the proportion of neonates and mothers in whom serum amyloid A (SAA) is detected when expected to have neonatal or maternal sepsis versus available biomarkers.
To identify the technical barriers to implementing of the SAA lateral flow test for the detection of neonatal sepsis, and maternal sepsis.
To understand the non-technical barriers to implementing and adopting the SAA lateral flow test for detection of neonatal sepsis and maternal sepsis.
To evaluate and implement a pre-existing technology for the rapid detection of neonatal and maternal sepsis in a resource-limited environment.
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Uganda |
2022-10-03 17:37:34 |
2025-10-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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