Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eugene Ruzagira
ID: UNCST-2023-R008282
A Phase Ib trial to evaluate the safety and immunogenicity of R21/Matrix-MTM in African children living with HIV.
REFNo: HS2496ES

Primary objective a) To assess the safety and reactogenicity profile of the malaria vaccine candidate R21/Matrix-MTM in 5-36-month-old African children living with HIV Secondary objectives a) To assess the humoral immunogenicity of R21/Matrix- MTM in 5-36-month-old African children, comparing children living with HIV with HIV negative children b) To assess the impact of vaccination on HIV reservoir c) To assess whether increasing age and nadir CD4 count are associated with immunogenicity of R21/Matrix-MTM in 5-36- month-old African children living with HIV Tertiary objectives a) To assess the immunogenicity profile of R21/Matrix-MTM in 5- 36-month-old African children, comparing children living with HIV with HIV negative children
Uganda 2022-10-20 18:13:49 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
Humanitarian Aid and Refugee Self-reliance
REFNo: SS1470ES

The overall objective of this study is to evaluate the impact of each of the interventions (see protocol) on selected socioeconomic and psychological wellbeing outcomes ,What are the mechanisms through which the interventions affect the primary and secondary outcomes? ,Which intervention is the most cost-effective in helping refugees improve their primary and secondary outcomes?,What is the impact of the interventions on school attandance and performance, aspirations and future orientation and self esteem and remittances (secondary outcomes),What is the impact of each if the interventions on economic prosperity, psychological wellbeing and ability to cope with adversity? (primary outcomes),
Uganda 2022-10-20 18:11:16 2025-10-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Proscovia Namuwenge Mukonzo
ID:
Assessing causes of mortality and loss to follow-up among people living with HIV in Uganda
REFNo: HS2499ES

To examine causes of death contributing to mortality among PLHIV. ,To describe the reasons patients discontinue treatment and no longer remain active in care.,
Uganda 2022-10-20 18:07:40 2025-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Human-centered design to adapt and inform an integrated chronic disease management program in Uganda using mobile payment services. (Acronym: IMPEDE CVD)
REFNo: HS2445ES

1)To understand patient and provider perspectives on the potential and acceptability of financing schemes and mHealth interventions aimed at strengthening behavior in relation to ideal drug availability and uptake among NCD patients (Work Package (WP) 1a).
2)To develop together with end-users a prototype for a mobile phone-based solution (including mobile-based nudges) to increase the availability and uptake of NCD drugs (WPs 1b, and 2).
3)To test the prototype, establishing proof of concept, and to assess end-users’ experiences interacting with two versions of the prototype (comparing two saving models), including how users make and evaluate payment management decisions, in preparation for a subsequent study (WP 3).
Uganda 2022-10-20 18:01:35 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
James Hintson
ID: UNCST-2022-R010009
Service Delivery and Public Infrastructure in Northern Uganda
REFNo: SS1476ES

The primary objective of the study is to describe and explain increases in service delivery, public infrastructure, and state-society interactions in Northern Uganda over time. The secondary objectives are to document community leaders’ satisfaction with the expansion of service delivery and public infrastructure construction, and to validate a separately collected dataset on public infrastructure throughout sub-Saharan Africa over time, as derived from satellite imagery.
USA 2022-10-19 10:58:32 2025-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
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