Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Riley Ravary
ID:
Governance in Transboundary Protected Areas: Analyzing Community Experiences at Mount Elgon National Park in Uganda
REFNo: SS148ES

The overall objective of this project is to understand the concept of protection by identifying who or what transboundary protected areas protect. (1) The first specific objective is to understand how governance of transboundary protected areas impacts local resources, residents, and resources users. (2) The second specific objective is to determine how protections are enacted in transboundary protected areas. (3) The third specific objective is to assess how persons who work, reside, and move through transboundary conservation areas balance the trade-off between protection and vulnerability.
USA 2018-08-07 2021-08-07 Social Science and Humanities Degree Award
Ronald Mayanja
ID:
CERVICAL CANCER AND ITS PRECURSORS IN HIV INFECTED YOUNG (BELOW THIRTY YEARS OLD) WOMEN AT MBARARA REGIONAL REFERRAL HOSPITAL, UGANDA.
REFNo: HS178ES

General Study Objective The main objective of this study is to determine the prevalence and factors associated with cervical cancer and its precursors among HIV infected young (below thirty years old) women at Mbarara Regional Referral Hospital. Specific Objectives 1. To compare the prevalence, histological types, trends and factors associated with cervical cancer amongst HIV-positive and HIV-negative young (below thirty years old) women attending the colposcopy and cervical pathology clinic of Mbarara regional referral hospital. 2. To determine the prevalence of high grade cervical intraepithelial lesions and associated factors among HIV infected young (below thirty years old) women at Mbarara Regional Referral Hospital. 3. To determine the factors associated with cervical intraepithelial neoplasia tissue Immunological response among HIV infected young (below thirty years old) women attending the colposcopy and cervical pathology clinic of Mbarara regional referral hospital? 4. To determine the epidemiological and prognostic factors associated with cervical cancer precursors among HIV infected young (below thirty years old) women at Mbarara Regional Referral Hospital.
Uganda 2018-08-07 2021-08-07 Medical and Health Sciences Degree Award
James Musinguzi
ID:
Evaluating the Efficacy of Institutional Systems in the Management of Wildlife Trade in Uganda
REFNo: SS215ES

To establish the nature of the management of wildlife trade in Uganda 2. To examine the influence of the institutional framework on the management of wildlife trade in Uganda 3. To investigate the influence of the legal framework on the management of wildlife trade in Uganda 4. To examine the moderating effect of management factors on the relationship between the institutional and legal framework and the management of wildlife trade in Uganda.
Uganda 2018-08-07 2021-08-07 Social Science and Humanities Degree Award
Zuzana Uhde
ID:
Transnational Migration and Challenges for Global Justice: EU–Africa Relations
REFNo: SS217ES

In the project I will study the perspective of Eastern Africa in order to understand the emerging global governance of migration and identify limits of the nation-state defined framework for global justice, which prevails in the social sciences as well as in the UN migration agenda and European migration policy. I will examine how global political economy impacts on Sub-Saharan Africa and to what extent it constitutes factors shaping migration between African countries and trans-continentally. Under the guidance of MISR I intend to learn from the local colleagues about the Eastern African and Ugandan context in order to understand its relation to the international migration regime. The project will connect a macro-structural perspective analysing global interactions with an analysis of international migration regime and its local effects. The innovative theoretical contribution of the project lies in developing a comprehensive framework that connects migration studies to the broader social theory of global interactions. The main objectives of the project are twofold: 1. developing a conceptual framing of migration in the context of global political economy juxtaposing the double approach of borderless for trade and border-restricted for responsibilities and social protection of migrants; 2. analysing emerging global governance of migration with a special assent on Africa–EU relations and the Ugandan context, and identifying key challenges for global justice.
Czech Republic 2018-08-07 2021-08-07 Social Science and Humanities Non-degree Award
Jade Siu
ID:
Trade Costs and cross border traders
REFNo: SS226ES

Broad objective: *To understand challenges to cross-border traders’ trading activities Specific objectives: *Understand how cross-border traders’ perspective of the One-Stop-Border-Post *Understand the barriers cross-border traders’ face in their day-to-day trading activities
UK 2018-08-07 2021-08-07 Social Science and Humanities Degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
Molecular evolution of Mycobacterium avium subsp. paratuberculosis in Africa
REFNo: A35ES

1. Study of MAP prevalence in two African countries (Sudan and Uganda) and evaluation in comparison to data of Europe and worldwide (To be done in Uganda and Sudan) 2. Analysis of the phylogeny of MAP strains from Africa based on genotyping and complete genomes (To be done in Sudan with samples from Sudan and Uganda) 3. Identification of virulence factors of selected MAP strains (To be done in Uganda). 4. Investigation of susceptibility and resistance genes of cattle to MAP (To be done in Uganda). 5. Creation of a risk map for paratuberculosis in Africa.
Uganda 2018-07-31 2021-07-31 Agricultural Sciences Non-degree Award
Andrew Kambugu
ID: UNCST-2019-R000823
Improving HIV treatment in pregnancy: A qualitative study on late antenatal care initiation, maternal disengagement from antiretroviral therapy, and the acceptability of dolutegravir in Uganda and South Africa.
REFNo: HS216ES

1. To investigate the barriers to and facilitators of the uptake of antenatal care early in pregnancy among women in urban and peri-urban communities in South Africa and Uganda. 2. To critically examine key factors that are associated with ART disengagement among women in urban and peri-urban communities in South Africa and Uganda, including: i. the barriers to and facilitators of ART initiation and adherence among late presenting pregnant women; ii. the role of pregnancy, breast-feeding and other post-delivery household and healthcare practices in ART disengagement among women; iii. the differences and similarities in the perceived side effects of dolutegravir and efavirenz among pregnant and post-partum women; iv. the role of community health workers in the delivery of HIV treatment services among pregnant and post-partum women. 3. To understand the key factors that are likely to influence a potential policy transition to and acceptability of dolutegravir in communities and health facilities in South Africa and Uganda.
Uganda 2018-07-27 2021-07-27 Medical and Health Sciences Non-degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
PREVALENCE OF GESTATIONAL DIABETES AMONG HIV-INFECTED WOMEN ATTENDING AN URBAN OUT-PATIENT CLINIC IN KAMPALA, UGANDA: A PILOT STUDY
REFNo: HS219ES

Primary • To determine the prevalence of GDM among HIV positive pregnant women using standard OGTT. Secondary • To describe the association between GDM and maternal/fetal outcome in HIV positive women. • To determine the prevalence of diabetes mellitus among HIV positive women previously diagnosed with GDM after birth using standard OGTT.
Uganda 2018-07-27 2021-07-27 Medical and Health Sciences Non-degree Award
Adriena De Visser
ID:
Global Health Electives: Ethical Engagement in Building Global Health Capacity
REFNo: SS229ES

Research Question: At sites where the Cumming School of Medicine (CSM) and other international institutions have long-standing collaborations in support of global health electives, what are the relationship dynamics as perceived by stakeholders in sub-Saharan Africa in regards to visiting medical trainee global health electives? Specific Objectives We aim to: 1)Explore and explain perspectives regarding the harms and benefits of global health electives from multiple stakeholders. 2)Explore and explain perspectives on how to create more equitable and mutually beneficial global health electives from multiple stakeholders. The stakeholder perspectives which we plan to include are those at the host site in Mwanza, Tanzania and Mbarara, Uganda: health facility administrators, host physicians, medical officers, nurses, local trainees, patients and/or family members, and a community leader.
Canada 2018-07-26 2021-07-26 Social Science and Humanities Degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Phase 3 Randomised Controlled Non-Inferiority Trial
REFNo: HS213ES

Primary Objective: To determine whether short-course high-dose L-AmB is as effective as 7-day amphotericin B deoxycholate-based treatment courses (current standard of care) in averting all-cause mortality in HIV-associated CM patients in a phase-III clinical endpoint trial. Secondary Objectives: 1. To determine the EFA in both treatment arms. 2. To examine the proportions of patients in each arm with clinical and laboratory-defined grade III/IV adverse events; median % change from baseline in laboratory defined parameters, by treatment arm. 3. To determine health service costs by treatment arm. 4. To determine all-cause mortality within the first 2 and 4 weeks. 5. To determine whether short-course high-dose L-AmB is superior to 7-day amphotericin B-based treatment courses (current standard of care) in averting all-cause mortality. 6. To determine rates of cryptococcal relapse / IRIS within the first 10 weeks by treatment arm. 7. To determine rates of disability at 10 weeks by treatment arm.
Uganda 2018-07-26 2021-07-26 Medical and Health Sciences Non-degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
Operational Research for Cryptococcal Antigen Screening (ORCAS) of HIV Patients: Evaluation of clinical and immunological predictors of outcomes.
REFNo: HS214ES

To identify incidence and risk factors for meningitis or death in asymptomatic CrAg+ persons before 6-months.
Uganda 2018-07-26 2021-07-26 Medical and Health Sciences Non-degree Award
Josephine Kayaga Nsubuga-Mugoa Kayaga
ID:
Successful Strategies for Using Knowledge Management in Small- and Medium-Sized Enterprises (SMEs)
REFNo: SS228ES

The purpose of the research study is to explore strategies that some SMEs managers use to effectively integrate Knowledge Management (KM) into their business practices; with the objective that the research study will enable me to make a contribution to positive social change as the findings from this study may be helpful in expanding opportunities for employees to learn new skills and knowledge. Another contribution to positive social change may be the expansion of employment opportunities because, as SMEs integrate KM into their business practices, SMEs may become more successful, leading to the expansion of employment opportunities.
Uganda 2018-07-26 2021-07-26 Social Science and Humanities Degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
The Social Context of Substance Use and HIV Risk in Kampala City, Uganda
REFNo: SS227ES

To conduct formative research to assess drug use in individuals living in Kampala and the associated contextual factors (drug use sites, sexual and drug networks) that may contribute to HIV injection and sexual risk behaviors.
USA 2018-07-26 2021-07-26 Social Science and Humanities Non-degree Award
Nando Lewis
ID:
Why do people flee their homes for UNHCR refugee assistance in Eastern Africa?
REFNo: SS212ES

This project aims to better understand South Sudanese refugee decision making before leaving their homes and in selecting their destination. I aim to go beyond the conflict causes displacement explanation, to investigate what levels of conflict and how other factors such as food insecurity influence the decision to flee ones home. I am also interested in better understanding why some South Sudanese travel to Uganda, whilst others travel to Kenya.
UK 2018-07-24 2021-07-24 Social Science and Humanities Degree Award
Krista Milich
ID:
Conservation to Coexist: Participatory Action Research for Wildlife Conservation and Community Development
REFNo: NS2ES

The goal of this project is to improve the conservation of wildlife in Kibale National Park and support capacity building of local people through a community conservation project. This project is focused on reducing human-wildlife conflict by using land use changes to prevent crop raiding by wild animals. Ultimately, by removing this conflict, the relationship between the local people and the park will improve and will support the conservation of endangered species.
USA 2018-07-17 2021-07-17 Natural Sciences Non-degree Award
Jeremy Springman
ID:
Public Opinion on Service Delivery and NGOs in Uganda
REFNo: SS170ES

Despite staggering growth in the delivery of public services by NGOs, little is known about how this shapes levels of citizen political engagement, confidence in government, and political accountability. This study will use a public opinion survey to measure whether receiving health services from an NGO causes an increase in levels of citizen engagement and confidence in government. To estimate whether receiving NGO-provided services influences the political attitudes of citizens who benefit from them, we will sample individuals in communities that have received NGO services and communities that have not.
USA 2018-07-17 2021-07-17 Social Science and Humanities Non-degree Award
Helena Newell
ID:
Natural Capital Accounting of the NWSC Katosi Water treatment Project, Mukono District
REFNo: NS51ES

Our objectives are to: 1. Develop and apply a framework for assessing and quantifying natural capital stocks and the ecosystem service provision before (the baseline) and on completion of a development project, with regard to the project’s impact on biodiversity. 2. Where possible and appropriate, value ecosystem service provision in monetary terms i.e. flows of benefits from Natural Capital stocks. 3. Understand how impacts and dependencies on the project’s Natural Capital vary between different stakeholder groups at local, regional and international levels 4. Make recommendations on measures to minimise losses of biodiversity and ecosystem services, and on measures for the project to achieve ‘no net loss’ 5. Compare these findings to those of an ESIA in order to see how NC approaches enhance and supplement ESIA approaches, and explore the uncertainties and limitations of the NC approach, particularly with respect to data limitations and methods for valuation, in order to make recommendations for future projects
UK 2018-07-17 2021-07-17 Natural Sciences Degree Award
Krista Milich
ID:
Red Colobus Monkey Reproduction and Conservation
REFNo: NS55ES

Long-term studies of wild primate populations are important for understanding how species adjust to environmental pressures and for examining models of our evolutionary past. My project uses the endangered red colobus monkey (Procolobus rufomitratus) of Kibale National Park, Uganda, as a model to understand how ecological stressors impact reproductive function, sexual behaviors, feeding ecology, and survival. Recent increases in hunting pressure and disease outbreaks have changed the selective pressures facing the Kanyawara red colobus monkeys. My previous work with these monkeys documented differences in behaviors and physiology for red colobus living in different habitats. Conducting further research on these animals will help to answer important questions about both endangered species and evolutionary processes. I request permission to study the behavioral and physiological responses of red colobus monkeys to ecological pressures. Specifically, I aim to: 1) re-evaluate the variation in reproductive and adrenal hormones of individuals living in different habitats, 2) examine behavioral variation over time of individuals in response to pressures from both hunting and disease outbreaks, and 3) monitor demographic changes and the health of this population. Long-term comparisons of the behavior and physiology of these individuals will provide data on the ability for primates to adjust to environmental changes.
USA 2018-07-17 2021-07-17 Natural Sciences Non-degree Award
Moses Nyago
ID:
Analyzing the Ugandan private sector and stakeholders’ views for voluntary support of REDD+ related activities through Corporate Social Responsibility (CSR)
REFNo: NS44ES

This study specifically: 1) Examines Uganda’s private sector firms’ CSR investments/support outside their core businesses and their influence on CSR support for REDD+ and related activities; and 2) Analyzes REDD+ stakeholder views on barriers of private sector firms to support/invest in REDD+ related activities through CSR and opportunities to diminish them in Uganda. The key research questions are: a) What do private sector firms in Uganda commonly support/invest in outside their core businesses under CSR? b) What is the influence of pooled voluntary CSR support, outside firms’ core business on the likelihood of CSR support for REDD+ related initiatives? c) How does private sector firm type and economic activity sector mediate in the relationship between CSR investments/support outside firms’ core business activities and CSR support/investment in REDD+ related initiatives? d) What are the barriers to REDD+ related support/investments under CSR in Uganda? e) What are the available opportunities to diminish the barriers for enhancement of CSR support to REDD+ related initiatives in Uganda?
Uganda 2018-07-13 2021-07-13 Natural Sciences Degree Award
Catherine Hobaiter
ID: UNCST-2019-R001480
Social structure and territory use in the chimpanzees of the Budongo Forest Reserve, Uganda
REFNo: NS56ES

East African chimpanzee society is characterised by a fission-fusion structure. The traditional view holds that all of the males within a chimpanzee community will range together and form close social bonds, whilst the females disperse, with less affiliation among non-kin (Wrangham, 1979; Goodall, 1968; Gibly and Wrangham, 2008). Much recent work focuses on understanding the nuances of, and variation within, chimpanzee social structure (see Aureli et al., 2008). We plan to investigate how population constraints, sex ratios, and territorial ranging interact with the chimpanzee communities’ social structures in the Budongo Forest. In particular we will explore how population characteristics and instability in the social structure might influence ranging decisions and social grouping over time. In the Budongo forest there are two habituated communities of chimpanzees: Waibira with around 120 individuals, in which habituation started in 2011, and Sonso with around 65 individuals, in which habituation started in 1990. These two neighbouring groups present a unique opportunity to explore the impact of social and environmental factors on chimpanzee territorial behaviour. Within the chimpanzee fission-fusion social system, members of a larger group form numerous subgroups that merge and split in response to social and ecological factors like food availability, predation pressure, and the presence of receptive females. While communities typically consist of 50-70 individuals with around 10-15 adult males, abnormally large communities exist in Ngogo (over 200 individuals) and Waibira (estimated 120 individuals), where over 30 adult males have been recorded. However, little is known about differences in social structure and associated consequences in these communities. One study has indicated clear subgrouping in the males of Ngogo, who range in two distinct ‘neighbourhoods’ rather than as a single unit (Mitani & Amsler, 2003). The result begs the question of whether this social structure is related to the unusual demographic size or is a consequence of other factors in Ngogo. Is there similar evidence of subgrouping amongst male chimpanzees in Waibira? If so, this may be an indication of the need to manage male-male social interactions when part of an abnormally large community. Indeed, Lehmann and Boesch (2004) reported that subgrouping patterns in chimpanzees of the Taï National Park in Côte d’Ivoire were dependent on total community size and number of males, with smaller communities exhibiting higher cohesiveness and a reduction in fluidity of the fission-fusion system. In addition to the number of individual males influencing subgrouping within a community, the presence of individual differences may also impact the male social structure. For example alpha male chimpanzees are known to exhibit different dominance styles that may be more cooperative or agonistic during their tenure as alpha (Foster et al., 2009). Furthermore, the fate of usurped males after they lose their alphaship may be related to their dominance style (Uehara et al., 2004). Changes in the rank of individual male chimpanzees may also impact the social behaviour of their relatives. While other male chimpanzees, even when closely related, represent possible competitors, female relatives such as mothers, or sisters who remain resident in their natal community, may adjust their social behaviour depending on the rank of their sons and brothers. One external environmental factor that may influence male chimpanzee subgrouping is the presence of human researchers. As we have long-term data available for the Waibira community we can compare the variation in territory use and in male subgrouping over the course of habituation, allowing us to explore the impact of habituation on chimpanzee behaviour. In addition to variation in the number and personality of males within a community, the use of territory and male sub-grouping may be impacted by the behaviour of neighboring communities. Chimpanzee intercommunity disputes are agonistic, and may include lethal aggression, particularly where a single male or small party encounters a larger number of males from the other community. As such they represent a significant pressure on chimpanzee use of territory. The number of males in a chimpanzee community influences how large the territory is, and when food availability is stable and abundant, it is thought that more energy is directed at territory utilisation and defense (Herbinger et al., 2001). Previous work from Kibale has also shown that on a given day, higher numbers of males in a party of chimpanzees will increase their tendency to patrol borders (Mitani and Watts, 2005). As periods of social uncertainty surrounding alpha changes can affect associative patterns and grooming behaviour, especially between males (see Koyama et al., 2017), it raises the question of how social instability impacts male territory usage. We will explore the almost 30-year data set of the Sonso chimpanzees in order to test whether or not the number of independent males, and/or the presence of individual males, impacts the size of the communities’ territory and their use of the areas within it. We will also investigate peripheral territory ranging in relation to alpha male transitions. Understanding the social grouping and ranging patterns over time will shed light on the function and motivation of chimpanzee territoriality. Understanding the ways that population characteristics, social relationships, and territory usage interact has implications for both ecological theory and for conservation management. Research Questions 1. Male subgrouping within communities (lead researcher Ms Bodden) ● Is there evidence of subgrouping or ‘neighbourhoods’ among male chimpanzees in the Waibira community? If so, how does this structure affect cohesion and stability? ● How does the Waibira community structure compare to that of the males in Sonso and how have subgroups changed over time? ● What effect have alpha male transitions had on subgrouping structure in the Waibira males? 2. Male use of territory in the Sonso community (lead researcher Ms Shearer) ● How does the number of independent males, and the leadership of individual alpha males influence the size and use of the Sonso territory? ● What social factors predict Sonso chimpanzees’ peripheral territory usage across seasons? We will explore the number of independent males, the identity of the alpha male, and the proximity to alpha male transitions. 3. Female association and subgrouping patterns (lead researcher Mr Chapoy) ● Do females who migrate from the same community preferentially associate with each other? We will explore the behaviour of the four confirmed immigrants from the Sonso community to the Waibira community. ● Do female relatives of independent males vary their use of the territory with variation in their male relatives ranks? We will explore the physical and social centrality of females who are closely related to males who move into or out of the top three rank positions.
UK 2018-07-13 2021-07-13 Natural Sciences Non-degree Award
Joanita Nangendo
ID:
HIV Self-Testing as a strategy to increase HIV testing uptake and linkage to prevention and care among men in Mpigi district
REFNo: HS226ES

Sub-study I • To determine prevalence and the associated factors of HIV testing among men in Mpigi district • To describe the barriers and facilitators of HIV testing among men in Mpigi district • To describe the perceptions of oral HIVST among men in Central1 Uganda Sub-study II • To determine the uptake and factors associated with oral HIVST among men in Mpigi district Sub-study III • To determine linkage to prevention, treatment and care, and the influencing factors among men using oral HIVST in Mpigi district Sub-study IV • To describe men’s experiences of using oral HIVST in Mpigi district • To describe the perceptions of oral HIVST among men who received but did not use oral HIIVST in Mpigi
Uganda 2018-07-13 2021-07-13 Medical and Health Sciences Degree Award
Ronald Kiguba
ID: UNCST-2019-R000844
Pharmacoepidemiology of the delayed initiation of prescribed antimicrobials among paediatric Inpatients at Mulago hospital
REFNo: HS211ES

Primary Objectives 1. To determine the incidence of delayed initiation of prescribed antimicrobials during index admission among paediatric inpatients at Mulago Hospital 2. To identify key risk factors for the delayed initiation of prescribed antimicrobials during index admission among paediatric inpatients at Mulago Hospital Secondary Objectives 1. To determine if there is an association between the delayed initiation of prescribed antibiotics during index admission and increased hospital stay in paediatric inpatients with sepsis at Mulago Hospital 2. To determine if there is an association between the delayed initiation of prescribed antibiotics during index admission and increased mortality in paediatric inpatients with sepsis at Mulago Hospital 3. To estimate the hospital readmission rates to any health facility post-index discharge among paediatric inpatients at Mulago Hospital 4. To estimate the incidence of suspected adverse drug reactions among paediatric inpatients at Mulago Hospital
Uganda 2018-07-05 2021-07-05 Medical and Health Sciences Non-degree Award
Hilda  Nakalema Sekabira
ID:
Evaluating the Impact of Early Initiation of Antiretroviral Therapy (ART) on Patient Outcomes Among HIV-Infected Adolescents and Young Adults in Uganda
REFNo: HS218ES

BROAD AIM: The broad aim of this study is to assess the impact of early initiation of ART on patient outcomes, over time, among adolescents and young adults (AYA), 15 - 24 years of age, living with HIV, in high-volume health facilities in Uganda before and after the implementation of the 2013 WHO ART treatment guidelines. SPECIFIC AIMS: Aim 1: To assess the effect of early ART on adherence to medication among AYA 15 - 24 years, before and after the implementation of the 2013 WHO ART treatment guidelines. Aim 2: To assess the effect of early ART on the rate of Opportunistic Infections (OI) episodes among AYA 15 - 24 years, before and after the implementation of the 2013 WHO ART treatment guidelines. Aim 3: To compare survival and predictors of survival among AYA 15 - 24 years, before and after the implementation of the 2013 WHO ART treatment guidelines.
Uganda 2018-07-05 2021-07-05 Medical and Health Sciences Degree Award
Tatiana Morais
ID:
"Women’s Talk”
REFNo: SS173ES

The main objective of this research project is to understand the camps’ context response to Gender-Based Violence (GBV). The focus will be on what the refugee considers to be the best practices already implemented and what can be improved. Also, Uganda does have a National GBV Database (NGBVD) which makes the country a pioneer in addressing and making visible GBV, thus, this research would like to learn from the Uganda good practices and policies.
Portugal 2018-06-26 2021-06-26 Social Science and Humanities Non-degree Award
Lillian Gimuguni Nabaasa
ID:
Educational Liberalization and the Quality of Teaching and Learning: A Perspective of Public and Private University Education in Eastern Uganda
REFNo: SS160ES

i. To find out the effect of educational liberalization on the profile of students entering the universities in eastern Uganda. ii. To establish the extent to which liberalization of education affects the quality of academic staff in universities in Uganda iii. To establish the effect of the Education Liberalization on the quality of teaching methods used in universities in Uganda. iv. To find out the extent to which liberalization affects the quality of teaching and learning environment in universities in Uganda
Uganda 2018-06-26 2021-06-26 Social Science and Humanities Degree Award
Shannon McFarlin Christa
ID: UNCST-2019-R001414
Skeletal life history research of Bwindi mountain gorillas
REFNo: NS42ES

Major Objectives for this project: Focusing on naturally accumulated skeletons from Bwindi mountain gorillas recovered in partnership with UWA, Institute of Tropical Forest Conservation (ITFC), and Max Planck Institute, our major objective is to generate new data on the morphology, developmental life history and health of wild mountain gorillas and understand how these aspects of their biology are influenced by ecology and behavior. Specific Aims: (1) Collect primary data on the skeletal and dental morphology of Bwindi gorillas, to: (a) with an initial focus on understanding skeletal correlates of behavior, such as diet; (b) document skeletal changes associated with aging and pathology in Bwindi gorillas; and (c) pursue comparative studies to characterize variation in these features between Bwindi and Virunga gorillas. (2) Initiate the first micro-anatomical studies of dental and bone development in Bwindi gorillas, to: (a) test hypothesized relationships between socioecology, development and life history in Bwindi gorillas, and as compared to Virunga gorillas; (b) investigate relationships between individual life history factors, health (where documented), and developmental defects in teeth and bones; and (c) investigate relationships between tooth and bone development and a key behavioral transition during development, weaning, as studied through fecal and plant food sampling. (3) Work with Ugandan staff of UWA and ITFC to build expertise in osteology, and local capacity for the long-term preservation and use of mountain gorilla skeletons as a scientific and educational resource in Uganda.
USA 2018-06-26 2021-06-26 Natural Sciences Non-degree Award
Moses Muwanguzi Mawanda
ID:
Testing Researhc March 2017
REFNo: A15ES

Objectives of the research project
Uganda 2018-06-23 2021-06-23 Agricultural Sciences Non-degree Award
Celia Taylor
ID:
COMPARING THE WORKLOAD AND KNOWLEDGE, SKILLS AND ATTRIBUTES OF COMMUNITY HEALTH WORKERS IN UGANDA
REFNo: HS207ES

The aim of this research is to determine how CHWs employed by Living Goods in Uganda spend their time and to identify the KSAs they use when undertaking CHW-related tasks/activities; comparing findings between CHWs identified as being “excellent” performers and other CHWs (whom will be “average” performers). The specific objectives are: • To examine the activities undertaken by CHWs during a typical “CHW day”. • To identify the KSAs demonstrated by CHWs as they undertake different activities. • To compare time use and KSAs between two groups of CHWs: those identified by programme managers as excellent performers and a random sample of all other CHWs. • To use the results of this comparison to identify the KSAs that distinguish excellent from average CHWs. • To qualitatively consider the content validity of the current selection process/tools used by Living Goods to determine whether they would help to identify those most likely to be excellent CHWs.
UK 2018-06-19 2021-06-19 Medical and Health Sciences Non-degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
Effect of preoperative bicarbonate infusion on Maternal and Perinatal outcomes of obstructed labour; A Randomised Controlled Trial
REFNo: HS217ES

To identify the risk factors, document the profile of electrolyte changes and establish the effect of a preoperative sodium bicarbonate infusion on maternal and perinatal outcomes among patients with OL in Mbale Regional Referral Hospital.
Uganda 2018-06-19 2021-06-19 Medical and Health Sciences Degree Award
SUSAN BALEKE ATUHAIRWE
ID: UNCST-2019-R001107
SAFETY, EFFECTIVENESS AND ACCEPTABILITY OF MISOPROSTOL FOR TREATMENT OF INCOMPLETE MID TRIMESTER ABORTION IN UGANDA
REFNo: HS153ES

1) To determine the burden of abortion morbidity among near-miss cases in Uganda. 2) To compare the safety and effectiveness of diagnosis and misoprostol administration by midwives versus physicians for management of incomplete mid trimester abortion. 3) Explore health workers’ experiences of and perceptions towards the use of misoprostol for management of incomplete mid trimester abortion. 4) To compare the acceptability of PAC using misoprostol by intervention type (midwives vs. physicians), in the mid trimester. 5) To determine the post abortion contraceptive uptake and continuation over 12 months for LARCs versus SARCs.
Uganda 2018-06-13 2021-06-13 Medical and Health Sciences Degree Award
WYCLIFF TUSIIME EDWIN
ID:
Teachers digital competence in the Teaching of Art and Design in Teacher Training Institutions in Uganda
REFNo: SS152ES

(i) to analyze if and how teachers use digital tools in the teaching of art and design?; (ii) to examine the challenges and /or opportunities teachers meet in the use of digital tools during teaching processes in Art and Design; (iii) to establish ways teachers can develop digital competence to enrich the teaching of art and design in TTIs?
Uganda 2018-06-13 2021-06-13 Social Science and Humanities Degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
Effect of host genotype on seropositivity to Mycobacterium paratuberculosis in Ankole cattle and immune activation of macrophages by recombinant heat shock protein 70 kd
REFNo: A32ES

To determine the seroprevalence of MAP in Ankole cattle in Rakai, Lyantonde and isingiro districts. To determine the allele frequencies of TL2-2, IFN-gamma, NOD2,SCL11A1, BoLA (DRB) genes in seropositive cattle and their case controls. To determine the association between serostatus and individual SNPs. To determine the effect of HSP70 immunisation on the activation of monocyte derived macrophages in invitro culture with MAP.
Uganda 2018-06-13 2021-06-13 Agricultural Sciences Non-degree Award
DENISH MOORTHY
ID:
Cost of Fortification of Maize Flour in Uganda
REFNo: HS191ES

The objective of this project is to prepare a background document that will help decision-makers better understand how producer start-up and operational costs and governmental monitoring and evaluation costs associated with maize flour fortification vary by scale of milling operations. Based on existing data and on data collected during this study, we will estimate the private and public sector costs of a (say) 10-year scale-up of a regional maize flour fortification program involving existing very small- and small-scale millers. These cost estimates, when set alongside estimates of micronutrient (MN) needs/deficiencies, and expected coverage of the proposed fortification program, can provide guidance regarding the costs of a maize fortification program among very-small and small-scale milling operations, and may also provide guidance regarding regional targeting of a maize flour fortification programs involving very-small and small-scale millers. For this study, we will also use available data on the private and public-sector costs of large-scale wheat flour fortification in Uganda; the results of this exercise may help decision-makers to compare the expected costs and nutritional benefits of wheat versus maize flour fortification programs.
India 2018-06-13 2021-06-13 Medical and Health Sciences Non-degree Award
Herbert Arinaitwe
ID:
Critical Success Factors (Csfs) For Institutionalisation of Monitoring and Evaluation Systems in Government: The Case of Justice, Law and Order Sector in Uganda
REFNo: SS171ES

i. To examine the relationship between leadership and the institutionalisation of monitoring and Evaluation in JLOS. ii. To examine the relationship between institutional set up and the institutionalisation of M&E in JLOS. iii. To examine the relationship between organisational culture and institutionalisation of M&E in JLOS.
Uganda 2018-06-13 2021-06-13 Social Science and Humanities Degree Award
Meghan Sobel
ID:
The Role of News Media in Rwanda and Uganda
REFNo: IS12ES

The objective of this study is to compare the media landscape in Uganda to the media landscape in Rwanda. Building on previous research that we have conducted via interviews with journalists in Rwanda, we aim to answer the following research questions: RQ1: What are the roles and functions of journalists in present-day Uganda? RQ2: How does Ugandan journalists’ use of social media compare to journalists in Rwanda? RQ3: How does Ugandan journalists’ use of constructive journalist compare to journalists in Rwanda? RQ4: How do Ugandan journalists perceive their level of press freedom compared to journalists in Rwanda?
USA 2018-06-13 2021-06-13 Social Science and Humanities Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Audit of current anticoagulant practices in the War-PATH Ugandan and South African clinical study sites
REFNo: HS179ES

1. To evaluate the current clinic service provision, drug availability, and current practices for warfarin prescription and dose adjustment at selected anticoagulant clinics in Uganda and South Africa 2. To evaluate the indications and demographic distribution and proportion of patients in therapeutic range among patients currently attending the anticoagulant clinics
UK 2018-05-30 2021-05-30 Medical and Health Sciences Non-degree Award
Peterson Kikomeko Kato
ID: UNCST-2019-R000881
Development and Validation of a Competency-Based Education Model for Strengthening Undergraduate Training in Human Nutrition and Dietetics in Uganda
REFNo: HS206ES

1.Responsibility towards participants: To be ensured by guaranteeing anonymity, ensuring absolute confidentiality, avoiding harm and avoiding betrayal and or deception. Obtaining voluntary informed consent from all participants and ensuring that the relationship between the researcher and the participants is based on honesty. 2.Ensuring legal requirements: Adhering to the legal requirements for conducting research in Uganda; avoidance of plagiarism, obtaining research approvals, ethical review, and research permit. 3.Knowing results of the research: Ensuring that respondents get to know the results from the research. 4.Responsibility towards the research community: Sharing results of the research with all participants and the general public
Uganda 2018-05-30 2021-05-30 Medical and Health Sciences Degree Award
Edwin Nuwagira
ID: UNCST-2019-R000930
ONE YEAR MORTALITY AND LOSS TO FOLLOW UP AMONG PATIENTS RECEIVING SECOND LINE ANTIRETROVIRAL THERAPY AT THE MBARARA REGIONAL REFERRAL HOSPITAL HIV CLINIC
REFNo: HS193ES

General objective; To determine the one year mortality and loss to follow up among patients on second-line ART at Mbarara regional referral hospital HIV clinic. Specific Objectives; 1. Determine the rate of loss to follow up among HIV positive patients in their first one year of taking second line ART. 2. Determine the factors associated with loss to follow up of patients on second line ART during the first one year of treatment. 3. Determine the one year mortality of patients on second-line ART. 4. Determine the factors associated with one year mortality among patients on second-line ART at Mbarara Regional Referral Hospital.
Uganda 2018-05-29 2021-05-29 Medical and Health Sciences Degree Award
Danse Anna Maria de Bondt Anna Maria
ID:
Traditional Drinks and Local Customs: The Everyday Experiences of Law and Governance in the Border Area of West Uganda.
REFNo: SS169ES

The consumption of alcoholic beverages is widely accepted in Ugandan society. Most popular are locally produced drinks such as tonto (banana wine), bushera ( sorghum beer), ajon (millet beer) and waragi (locally distilled gin), especially in rural areas. The drinks are locally produced in homes, sold and consumed by families and friends in the area and even traded and distributed throughout the country as well as abroad, as in the case of waragi. Many of these drinks have been made for generations and are considered in society to be part of a traditional way of life. They are consumed on social events, such as funerals, weddings and festive celebrations such as Christmas. This study is situated within larger debates surrounding law, culture, local customs and trade in Africa. The central aim of this research is twofold: to understand the everyday practices and experiences of the people that are involved in production, trade and consumption of locally produced drinks in the border area of West Uganda; and to understand the role that different actors have in governing this trade. In order to understand how these concepts work out in everyday life, practice theory will serve as a lens with which to understand the social power relations of the variety of actors that live at the border. To address these issues my main research question will be: “How does the relationship between state officials and people involved in unregulated alcohol practices shape law and governance in the border area of West Uganda?”
Netherlands 2018-05-29 2021-05-29 Social Science and Humanities Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Adherence to 3TC/TDF PrEP as a Bridge to ART: A Pilot Evaluation
REFNo: HS208ES

1) Evaluate uptake and adherence to 3TC/TDF PrEP among HIV-uninfected partners, when implemented as a bridge to ART 2) Assess factors related with adherence to 3TC/TDF PrEP
Uganda 2018-05-29 2021-05-29 Medical and Health Sciences Non-degree Award
Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
The Epidemiology of Type 1 Diabetes in Uganda
REFNo: HS209ES

General Objective To study the epidemiology of T1D in Ugandan Youths Specific Objectives 1. To ascertain the newly diagnosed (2009 – 2018) incident T1D in youth age < 25 years in order to assess the temporal trends in presentation of diabetes for the period 2009 – 2018, by age, sex and ethnicity. Specific characteristics to be examined are: age at onset of diabetes, markers of disease severity (diabetic ketoacidosis; residual insulin secretion – C-peptide; HbA1c), markers of insulin sensitivity (waist circumference, body mass index), Cardiovascular risk factors (lipid profile, blood pressure, microalbuminuria). 2. To determine the prevalence and incidence of, and risk factors for chronic microvascular (retinopathy, nephropathy, and autonomic neuropathy) and selected markers macrovascular complications (hypertension) of diabetes. 3. To assess the incidence of, and risk factors for, serious acute complications of diabetes, including severe hypoglycaemia and diabetic ketoacidosis (DKA). 4. To assess total and cause – specific mortality among 2009 – 2018 incident cases for the period from the date of diabetes diagnosis through March 31, 2018 5. To determine the extent to which barriers to access care and barriers to quality of care, impact on management outcomes. 6. To provide consultation and support to inform the development of low-cost sustainable public health surveillance systems of childhood diabetes in Uganda. 7. To assess growth and glycaemic control of children and adolescents diagnosed with T1DM . 8. To determine the effect of psychosocial support (camps and / parents meeting) on Diabetes care in children and youth with DM
Uganda 2018-05-29 2021-05-29 Medical and Health Sciences Non-degree Award
Amy Patterson Stephenson
ID:
“Shaping Citizenship: Christian Institutions and Urban Youth in Africa”
REFNo: SS190ES

This project explores the relationship between Christian institutions (such as ecumenical bodies, denominations and individual congregations) and youth citizenship in urban Africa. The project seeks to answer three questions: (1) How do Christian institutions shape citizenship norms and behaviors among African youth? (2) How do Christian institutions prioritize particular citizenship norms and behaviors, depending on the gender and economic standing of youth? (3) How do these Christian efforts influence how youth themselves understand citizenship and act on that understanding? To answer the questions, the project will include fieldwork in urban Kampala district. Outputs will include an academic presentation, academic articles and potentially, a book.
USA 2018-05-29 2021-05-29 Social Science and Humanities Non-degree Award
Dorothy Stamps Sarah
ID: UNCST-2019-R001036
Quantifying Plume-Lithosphere Interactions from GNSS Geodesy, Seismology, and Geodynamic Modeling
REFNo: PS4ES

1) Install 3 Global Navigation Satellite System (GNSS) stations in Uganda 2) Assess surface motions using geodynamic modeling
USA 2018-05-24 2021-05-24 Natural Sciences Non-degree Award
wasswa william
ID: UNCST-2019-R001217
Automated Diagnosis and Classification of Cervical Cancer from Pap-Smear Images.
REFNo: HS129ES

The general objective of this research is to design and validate a robust automated tool for diagnosis and classification of cervical cancer using hybrid Segmentation and Classification techniques applied to Pap smear images. To achieve this objective and address the research problem, the following specific research objectives have been formulated. 1. To review state of art prominent recent publications focusing on the application of machine learning and medical imaging in automated detection and classification of Cervical Cancer from Pap-smear images. 2. To acquire Pap-smear images and develop a hybrid technique for automated segmentation and classification of cervical cancer. 3. To develop an interactive graphical user interface (GUI) platform to facilitate the automated diagnosis and classification of cervical cancer from Pap-smear images. 4. To test and validate the developed platform using patient results obtained from a manual screening of the Pap-smear images by a trained and experienced cytologist and also comparing the algorithms with results obtained by other researchers on the same open source datasets (Hervlet Cervical cancer dataset).
Uganda 2018-05-22 2021-05-22 Medical and Health Sciences Degree Award
Aleksey Maro
ID:
Frugivory and fermentation: a study of fruit-ethanol concentrations and olfactory plume availability for chimpanzee-consumed fruits
REFNo: NS41ES

To collect fruit ethanol data, as it relates to the diet of chimpanzees; to determine the ecological role of ethanol in nature, including relevance to human alcohol consumption. (i) To assess the ethanol concentrations and physical properties (relative to ripeness) of fruit available to wild chimpanzees; (ii) to systematically collect, analyze, and map atmospheric ethanol vapor levels in relation to distance from ripe fruit crops of trees and shrubs.
USA 2018-05-22 2021-05-22 Natural Sciences Degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
Evaluation of novel diagnostics and biomarkers for childhood TB
REFNo: HS169ES

Our primary specific aim is: 1. To determine the diagnostic accuracy of a novel breath sensor for diagnosis of childhood TB. Our secondary aims are: 1. To determine if breath volatile organic compounds (VOCS) (methyl nicotinate and methyl-p-anisate) can be used to monitor response to anti-TB treatment in children. 2. To assess the accuracy of point of care (POC) C-Reactive Protein (CRP) as a triage test among children suspected of having TB
Uganda 2018-05-22 2021-05-22 Medical and Health Sciences Non-degree Award
Priya Kumar
ID:
Technology to Enable Universal Health Coverage - Watsi Implementation Research
REFNo: HS181ES

General Objective - To determine if a technology intervention reduces the time and cost of administering community based health insurance compared to a paper based system. The specific objectives of conducting the research include: 1. To estimate with excellent accuracy and precision the mean and median time of each of the five components of the CBHI system (member enrollment, identification, claims submission, claims approval, reporting), and of the total time for both intervention and the control cohort. 2. To estimate with excellent accuracy and precision the mean and median cost of each of the five components of the CBHI system, and of the total cost for both intervention and the control cohort. 3. To estimate with excellent accuracy and precision the difference in the mean and median time and cost between the intervention and the control cohort for each of the five components, and the total of all five components for the CBHI system. 4. To identify factors other than the technology intervention that could potentially be associated with total duration time and cost.
USA 2018-05-22 2021-05-22 Medical and Health Sciences Non-degree Award
HUSSEIN ORIA
ID:
ARV Medicines usage in farm chicken; exploring the perceptions of the community: a case for Wakiso district.
REFNo: HS188ES

Determine extent of use of ARVs in farm chicken and explore the perceptions of the community on use of ART medicines in farm chicken. With specific objectives as; Understand the extent of ARV usage in farm chicken. Explore community perceptions on ARV misuse in farm chicken. Examine the extent of ARV usage in preparation of chicken feeds. Determine ARV content in farm chicken. Determine the content of ARV in chicken feed
Uganda 2018-05-22 2021-05-22 Medical and Health Sciences Non-degree Award
Bethany WILLIAMS LIN
ID:
Testing the functional significance of divergent reproductive traits in an African cichlid fish (Pseudocrenilabrus multicolor victoriae)
REFNo: NS52ES

The goal of the proposed research is to better understand the influence of environmental stressors (such as turbidity, hypoxia, and increased temperature) on the divergence of reproductive traits in an African cichlid fish (Pseudocrenilabrus multicolor victoriae). My specific objectives will be to (a) determine the functional role of physiological and behavioral trait changes between populations of P. multicolor, and (b) test the adaptive significance of trait changes by assessing performance of lab-reared fish on reproductive tasks. (c) present conservation education materials about the importance of biodiversity to water quality to local schools through The Water Project
USA 2018-05-22 2021-05-22 Natural Sciences Degree Award
William NESBITT Alexander
ID:
Causes and implications of the depletion of effective calcium concentrations in Lake Nabugabo, Uganda, East Africa
REFNo: NS53ES

To re-evaluate the work of Beadle (1981) and accurately measure the calcium and other major ion concentration of Lake Nabugabo and the surrounding wetlands. To identify the sink of calcium in the system to see why the concentration is so low compared to other lakes in the LVB. To explore the implications of low calcium by investigating the Ca/P ratio in Nile perch and mukene in both Lake Nabugabo and Lake Victoria to determine the effects on its bone strength, density and growth.
Canada 2018-05-22 2021-05-22 Natural Sciences Degree Award
Joel HARTTER Nathan
ID:
Population, Environment, and Climate in the Albertine Rift
REFNo: NS37ES

To Determine how coupled climate and anthropogenic landscape change impacts the dynamics and resilience of a protected areas and the surrounding human population, including impacts to human and wildlife health, food security, and governance.
USA 2018-05-18 2021-05-18 Natural Sciences Non-degree Award
Fiona Cresswell
ID:
High dose oral and intravenous rifampicin for adult tuberculous meningitis: an open-label phase II randomised controlled trial
REFNo: HS136ES

1. To determine whether higher-dose rifampicin, delivered orally at 35mg/kg/day or delivered intravenously at 20 mg/kg/day (for 2-weeks, followed by orally at 35 mg/kg/day for 6-weeks) provide equivalent plasma and CSF exposures, and whether the exposure profiles are favourable compared to the standard dose oral rifampicin. The pharmacokinetically optimal dose and route of administration of rifampicin can then be taken forward into a phase III clinical trial. 2. To observe whether greater rifampicin exposure in CSF is associated with any clinical benefit including more rapid resolution of coma, reduced neurocognitive deficit or reduced mortality. 3. To determine the diagnostic accuracy of Xpert MTB/Rif Ultra for TBM (ancillary study 1) 4. To describe the concentration of rifampicin in brain tissue in each treatment arm (ancillary study 2) 5. To explore the use of bedside ultrasound as a monitoring tool to improve supportive care for people with TBM (ancillary study 3)
UK 2018-05-15 2021-05-15 Medical and Health Sciences Degree Award
Moses Ocan
ID: UNCST-2020-R014731
Antimalarial resistance in Sub-Saharan Africa: Assessing spread of artemisinin resistance and chloroquine resistance reversal among Plasmodium falciparum parasites
REFNo: HS168ES

1) To determine through a systematic review, the extent of chloroquine resistance reversal among Plasmodium falciparum parasites in malaria endemic countries since the change in policy 2) To determine the association between four (4) most reported K13 gene polymorphisms in Sub-Saharan Africa and artemisinin susceptibility among Plasmodium parasites 3) To predict using a model the spread to Sub-Sahara African (Uganda) Plasmodium falciparum parasite population of the K13 propeller gene polymorphisms detected in Southeast Asia and associated with artemisinin resistance
Uganda 2018-05-15 2021-05-15 Medical and Health Sciences Degree Award
Kirsten Ward
ID:
Evaluation of delivery practices for multiple vaccines at a single immunization visit in low- and middle-income countries Uganda
REFNo: HS170ES

Aim: This evaluation aims to describe current preparation, administration and communication practices in the delivery of more than one vaccine to a single child at a single immunization visit in Uganda. Objectives: 1. To document the processes and techniques used to prepare and administer more than one vaccine, primarily injectable vaccines, to children in Uganda; 2. To understand the timing, content, and extent of communication messages about co-administration of one or more vaccines and post-vaccination care delivered by providers to caregivers in Uganda; and 3. To use results from 1 & 2 to develop recommendations about best practices for: a) the preparation and delivery of multiple vaccines with a focus on injectable vaccines, and b) provider communication to the caregiver about delivery of multiple vaccines and post-vaccination care.
Australia 2018-05-15 2021-05-15 Medical and Health Sciences Non-degree Award
Damalie Nakanjako
ID:
Inflammation and immune aging among HIV-infected adults with at least 12 years of antiretroviral therapy in an African cohort.
REFNo: HS194ES

1. To describe innate system phenotype and function [Natural killer (NK) cells, monocytes and innate lymphoid cells (ILCs)], after long-term suppressive HAART for at least 12 years of HAART, within the Infectious Diseases Institute (IDI) HIV treatment cohort. 2. To determine levels of immune aging markers among HIV-infected adults with suppressive ART, relative to age-and gender-matched HIV negative counterparts, despite twelve years and more of suppressive ART. 3. To describe those biological pathways which remain deranged after at least 12 years of suppressive HAART, and identify markers/pathways that are known to increase the risk of non-AIDS complications of chronic HIV.
Uganda 2018-05-15 2021-05-15 Medical and Health Sciences Non-degree Award
Joy Gumikiriza- Onoria Louise
ID:
SELF - PERCEPTIONS OF AGING AND QUALITY OF LIFE AMONG THE ELDERLY IN UGANDA
REFNo: HS195ES

To 1) Examine the association between quality of life and perceptions of aging among older people in rural and urban Uganda, 2) Translate and culturally adapt the Brief Aging perceptions questionnaire (B-APQ), and 3) Translate and culturally adapt the Older People’s Quality of Life questionnaire (OPQOL) for use with Luganda speaking older people in Uganda.
Uganda 2018-05-15 2021-05-15 Medical and Health Sciences Non-degree Award
Caitlin Jenks Alexandra
ID:
EVALUATION OF ANEMIA PREVENTION EFFORTS AFFECTING YOUTH IN IGANGA, UGANDA; CASE OF MUSANA COMMUNITY DEVELOMENT ORGANIZATION
REFNo: HS198ES

General Objective To evaluate the quality of the current anemia prevention efforts at MCDO, as well as the behavior and beliefs around anemia from healthcare workers and other staff, so the findings can be used to enhance the organization’s strengths, and implement recommended changes. Specific Objectives Objective 1 To evaluate, through staff interviews and a research survey tool, the MCDO staff’s current knowledge and beliefs on anemia and how much emphasis they deem should be placed on prevention efforts. Objective 2 To find out, through staff interviews and observations, if there are any current prevention efforts surrounding anemia on MCDO’s campuses including nutrition education, supplementation, deworming policies, and malaria prevention strategies. Objective 3 To observe and evaluate qualitative data on the student’s consumption of food on a weekly basis, living quarters, classrooms, dining areas, and footwear of the nursery and primary school students at MCDO.
USA 2018-05-15 2021-05-15 Medical and Health Sciences Degree Award
Pakoyo Kamba Fadhiru
ID:
Burden and drivers of controlled prescription drug abuse among selected populations in Uganda
REFNo: HS203ES

The goal of this project is to determine the magnitude and factors associated with controlled prescription drug abuse among selected high risk populations in Uganda. There are five specific objectives: • To establish the prevalence of controlled prescription drug abuse among health care workers in Uganda. • To establish the prevalence of controlled prescription drug abuse among patients with mental disorders in Uganda. • To establish the drivers of controlled prescription drug abuse among health care workers and patients with mental disorders in Uganda. • To establish the compliance of Uganda’s medicine supply chain to regulations on controlled prescription drugs. • To establish the factors associated with compliance of Uganda’s medicine supply chain to regulations on controlled prescription drugs
Uganda 2018-05-15 2021-05-15 Medical and Health Sciences Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
ASSESSMENT OF THE INFORMED CONSENT PROCESS FOR STUDIES INVOLVING GENETIC RESEARCH AMONG PEOPLE LIVING WITH HIV AT THE INFECTIOUS DISEASES INSTITUTE (IDI)
REFNo: HS199ES

1. To assess the adequacy of informed consent documents used for pharmacogenetic research and the collection, storage and future use of human samples. 2. To determine the methods used by researchers to ensure research participants’ understanding during the informed consent process in pharmacogenetic research. 3. To assess the factors that influence participants’ understanding during the consent process in pharmacogenetic research
Uganda 2018-05-04 2021-05-04 Medical and Health Sciences Degree Award
Jenna  Wozniak Marie
ID:
Community Knowledge, Attitudes, and Practices Around Individual Blackfly Control and the Diseases They Transmit in Northern Uganda
REFNo: HS200ES

The objective of this research project is to determine what individual level control efforts are being used to protect against blackfly biting within communities. Although large-scale control efforts have been implemented in onchocerciasis endemic regions, individual level control efforts are not well recorded or understood. Through the use of a KAP (knowledge, attitudes, and practices) survey it is hoped that this will be understood. Demographic data will also be collected to find correlations between knowledge and education level. Future application of this information can be used to either modify existing methods or to suggest personal control methods for communities where onchocerciasis and nodding syndrome are endemic. This project will take place in the district of Kitgum and Lamwo in northern Uganda were both onchocerciasis and nodding syndrome have been observed. Over a five-week period, I will travel to several communities within each district to conduct my survey. The research question of this project is what do individuals in communities where onchocerciasis and nodding syndrome are observed know as well as perceive about blackflies and what practices do they use to prevent blackfly biting?
USA 2018-05-04 2021-05-04 Medical and Health Sciences Degree Award
Pakoyo Kamba Fadhiru
ID:
Elucidating the mechanism of interaction of mycobacteria rhomboid proteases with their specific substrates
REFNo: NS49ES

The goal is to elucidate the mechanism(s) of interaction of mycobacteria rhomboid proteases with their specific native substrates. There are three specific objectives: • To identify the native peptide substrates for mycobacteria rhomboid proteases. • To elucidate the substrate residues essential in interaction with mycobacteria rhomboid proteases. • To elucidate the mycobacteria rhomboid protease residues essential in interaction with their substrates.
Uganda 2018-04-30 2021-04-30 Natural Sciences Non-degree Award
Andrea  Calcagno
ID:
Using Calcaneal Quantitative Ultrasound (cQUS) and urine Retinol Binding Protein to screen HIV-infected cART-treated patients for reduced bone mineral density: a pilot study
REFNo: HS204ES

Primary objective: To compare DEXA and cQUS in predicting reduced BMD in a population of Ugandan HIV-infected individuals on long-term cART. Secondary objective: To assess the prevalence of abnormal RBP/Cr and the correlation between abnormal RBP/Cr and reduced BMD.
Italy 2018-04-30 2021-04-30 Medical and Health Sciences Non-degree Award
Michael Juma
ID:
EXAMINING THE EFFECT OF SERVICE DELIVERY FACTORS ON TIMELY INITIATION OF TUBERCULOSIS TREATMENT WITHIN PRIMARY CARE SETTINGS IN UGANDA
REFNo: HS205ES

The study goal is to examine the association between service delivery factors and timeliness of Tuberculosis treatment initiation within accredited primary care facilities in Uganda. Here service delivery factors are characteristics relating to HF structure and care delivery. The specific aims are: Aim 1: To explore the association between service-delivery factors (structural and care delivery characteristics) and process timeliness (diagnosis time, laboratory turnaround time and treatment initiation time) Aim 2: To measure the association between process timeliness and Tuberculosis treatment initiation Aim 3: Describe perspectives of healthcare workers (in-charges of outpatient departments, heads of clinical teams and heads of laboratories) within each accredited health facility on preventing delays in diagnosis and initiation of Tuberculosis treatment.
Uganda 2018-04-30 2021-04-30 Medical and Health Sciences Degree Award
Jack  Horowitz Rosengarten
ID:
Community-Driven Financial Solutions to Human-Wildlife Conflict in Uganda's Albertine Rift Eco-Region
REFNo: SS176ES

1. Policy objective: Uncover and clearly illustrate any institutional challenges of the Human-Wildlife Conflict Resilience Fund (HWCRF) project that may exist which are unique to Uganda’s Albertine rift region (UAR) in order to (a) strengthen the long-term implementation of the HWCRF project and (b) provide lessons learned for other governments and communities looking to implement human-wildlife conflict (HWC) financial instruments within similar geographies. 2. Academic objective: Contribute to the literature by bridging HWC insurance research outside of Sub-Saharan Africa with previous studies on HWC within UAR which have yet to formally analyze HWC financial instruments.
USA 2018-04-25 2021-04-25 Social Science and Humanities Degree Award
Simon Wakwale Peter
ID:
POLITICAL DECENTRALISATION AND LOCAL GOVERNMENT PERFORMANCE: A CASE STUDY OF MBALE MUNICIPAL COUNCIL
REFNo: SS76ES

1. TO EXAMINE THE EFFECT OF DEVOLUTION OF POWERS ON TIMELY ACCOUNTABILITY IN MBALE MUNICIPAL COUNCIL 2. TO ASSESS THE EFFECT OF DEVOLUTION OF POWERS ON INFRASTRUCTURAL DEVELOPMENT IN MBALE MUNICIPAL COUNCIL 3. TO ESTABLISH THE EFFECT OF DEVOLUTION OF POWERS ON PROVISION OF SOCIAL SERVICES IN MBALE MUNICIPAL COUNCIL 4. TO FIND OUT THE EFFECT OF DEVOLUTION OF POWERS ON POLICY IMPLEMENTATION IN MBALE MUNICIPAL COUNCIL
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
CHRISTOPHER  OPIO KENNETH
ID:
Analysis of the genetic determinism of hepatocellular carcinoma (HCC)
REFNo: HS125ES

1) Determine the association between chosen genetic markers among patients with HCC compared with subjects from Uganda with advanced liver fibrosis (F4 or cirrhosis). 2) Explore additional genetic markers of HCC by selected sequencing (targeted sequencing and exome sequencing) of the genome of subjects with HCC compared to controls from Uganda. 3) Determine whether these markers correlate with the clinical stages of HCC and could be predictive of HCC progression. 4) To describe clinical outcomes of advanced liver fibrosis (F4 or cirrhosis) or HCC over the study follow-up period.
Uganda 2018-04-24 2021-04-24 Medical and Health Sciences Non-degree Award
Tiffany Basciano Nicole
ID:
No One Left Behind? A Study on the Human Rights of Women Living With HIV/AIDS in Uganda
REFNo: SS140ES

A study on adult women living with HIV/AIDS in Uganda. The study will include an examination of how women’s rights are integrated into HIV/AIDS-related laws, policies, programs, and initiatives in Uganda. We will further examine any challenges that women may face in family life, healthcare settings, or in the workplace because of their status, as well as any distinction in the experiences of women in urban versus rural settings. We hope that this research will help support the achievement of Sustainable Development Goals (SDGs) 3 – good health and well-being and 5 gender equality.
USA 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Specioza  Twinamasiko
ID:
Oil discovery and compensation over land: Conceptualizing risks and vulnerabilities of women's household livelihoods i Albertine Graben, Uganda
REFNo: SS147ES

i- To discover the nature of oil related land contestations in the Albertine Graben. ii- To explore the risks and vulnerabilities experienced by women after oil discovery. iii- To examine land compensation processes before and after eviction. iv- To Explore the role of women in the land compensation process. v- To examine the strategies women have put in place to improve their livelihood.
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Richard Wamimbi Wotti
ID:
Community Systems and Practices to Prevent and Respond to Violence Against Children in Uganda: Children's perceptions and lived experiences.
REFNo: SS158ES

1.Find out the perceptions and lived experiences of children most especially girls in preventing and responding to Violence Against Children in their communities. 2.Establish what the formal (education and social welfare) and non formal (family , faith based, traditional) approaches to child protection are and how they are being applied in creating safer communities in Uganda free from violence. 3.Examine how the formal and non-formal elements of community referral and reporting mechanisms are functioning to prevent and respond to Violence Against Children. 4.Explore how girls are affected by different forms of violence and how they are supported to enable them live in an environment that is free from all forms of violence throughout their life course
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Wilfred Kokas Aupal Kokas
ID:
Change Management Practices and Performance of Selected Local Governments in Eastern Uganda
REFNo: SS165ES

1. To establish the relationship between executive support and performance of selected Local Governments in Eastern Uganda. 2. To assess the relationship between effective communication and performance of selected Local Governments in Eastern Uganda. 3. To investigate the relationship between employee involvement and performance of selected Local Governments in Eastern Uganda
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Michael Carter Ross
ID:
Smallholder Farmers’ Returns and Learning from Subsidized Inputs in Uganda
REFNo: SS145ES

The Government of Uganda is launching an agricultural input subsidy program through an electronic voucher and we have the opportunity to study its first implementation phase (5,000 households) and provide lessons for scaling up the full program (450,000 households) by evaluating, inter alia, how different subsidy schemes affect the spread of technology to poor households and their networks and women farmers and their networks.
USA 2018-04-20 2021-04-20 Social Science and Humanities Non-degree Award
Jacent Kamuntu  Asiimwe Kamuntu
ID:
BASELINE ASSESSMENT OF KNOWLEDGE, ATTITUDES AND PRACTICES ON HEALTH AND NUTRITION AMONG CAREGIVERS AND PREGNANT WOMEN IN LIVING GOODS OPERATIONAL DISTRICTS
REFNo: HS192ES

To assess and document existing knowledge, attitudes and practices of caregivers and pregnant women in Living Goods’ areas of operation on, nutrition and other health seeking behaviour during pregnancy as well as infant and young child feeding – (IYCF) practices.
Uganda 2018-04-20 2021-04-20 Medical and Health Sciences Non-degree Award
Mael Leroux
ID:
Dual articulation in the communication system of chimpanzees
REFNo: NS47ES

The emergence of combinatoriality (phonology and syntax) in human language represents one of the key evolutionary transitions in life (Maynard Smith & Szathmary 1995). Despite its significance, we know very little regarding how unique this capacity is to humans or the evolutionary progression of this trait. By searching for core features of language, such as its combinatoriality, in the communication systems of closely related species to humans, particularly the primates, it is possible to shed light on whether the components of language are de novo evolved traits in humans or whether they have their origins rooted in the primate lineage. With this project, I aim to shed light on how unique combinatorics is to human language through empirically investigating the presence of linguistic forms of phonology and syntax in our closest living relative, the chimpanzee.
France 2018-04-20 2021-04-20 Natural Sciences Degree Award
JIMMY SSEMALULU
ID:
PRESCRIPTION PRACTICES AND USE OF LABORATORY PARAMETERS TO MONITOR EFFICACY AND TOXICITY OF ANTIRETROVIRAL THERAPY (ART) AMONG HIV PATIENTS (15YEARS AND ABOVE) AT ART CLINIC IN BUTABIKA NATIONAL PSYCHIATRIC REFERRAL HOSPITAL, UGANDA.
REFNo: HS151ES

STUDY OBJECTIVES General objective To assess prescription practices and use of laboratory parameters to monitor efficacy and toxicity of ART among HIV patients (15 years and above) at ART clinic in Butabika hospital. 1.5.2 Specific objectives 1. To describe pharmaceuticals prescribed for HIV patients (15 years and above) at ART clinic in Butabika hospital. 2. To determine drug drug interactions between ARVs and other medicines prescribed to HIV patients (15 years and above) at ART clinic in Butabika hospital. 3. To identify laboratory parameters used to monitor treatment response and toxicity of ARVs among HIV patients (15 years and above) on ART in Butabika hospital.
Uganda 2018-04-11 2021-04-11 Medical and Health Sciences Degree Award
Laura Bogart
ID:
GAME CHANGERS: A PILOT INTERVENTION TO EMPOWER HIV CLIENTS AS PREVENTION ADVOCATES IN UGANDA (PHASE 2)
REFNo: SS166ES

Primary objectives include: Assessing preliminary intervention effects on: a) protective behavior of the HIV-positive clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART adherence) b) diffusion of prevention messages across the network, as assessed by the content and extent of communication with network members about protective behaviors (condom use, partner concurrency/number of partners, HIV testing, engagement in HIV care, circumcision), HIV disclosure, and HIV stigma
USA 2018-04-11 2021-04-11 Social Science and Humanities Non-degree Award
CHARLES LUGERO
ID:
A global registry to study the demographics, socioeconomic and clinical factors, etiologies, pathophysiology, management, barriers to care, and outcomes of heart failure patients
REFNo: HS144ES

Study 1. Estimate the incident rate of outcomes in HF patients in world Objectives regions and overall, and assess social and lifestyle factors (demographics, socioeconomic variables, clinical risk factors, diet, medication use, and health‐related quality of life), etiologies and variations in treatment patterns that might influence mortality and morbidity. 2. Describe determinants of different HF phenotypes (HFpEF, HFrEF, HF due to valvular disease, ALVD) in these world regions, and their management and outcomes. G‐CHF Protocol Page 3 2016‐09‐26 Version 1.2 3. Describe the potential role of biomarkers (BNP/NT‐proBNP and troponin, as available), related genetic determinants, and their relation to clinical factors, treatments, and type of HF 4. Assess non‐cardiac co‐morbidities at enrolment, their incidence during the study and how they influence outcomes from both cardiovascular and non‐cardiovascular mortality and morbidity. 5. In a sub‐study of approximately 4000‐5000 patients, perform measures of frailty, cognitive and lung function, mental health, adherence to medication, and dietary assessment, with collection of blood and urine samples for central analysis, to further understand the pathophysiologic changes in HF and their relation to outcomes. 6. Describe patient and system barriers to HF care in a global HF population.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Clémence Bonneaud
ID:
Pant-hoot call in immature chimpanzees
REFNo: NS40ES

We will describe the age at which pant-hoot production starts. We will examine the order in which the four phases of the pant-hoot call develop. For example: is development sequential with the order of the final pant-hoot call, or do later phases (the climax) develop before early ones. We will investigate at what point multiple elements are produced within a call, and whether the sex differences seen in the pant-hoot calls of adults are also seen during development.
France 2018-04-04 2021-04-04 Natural Sciences Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Clinical and genetic factors influencing variability in warfarin dose requirements in Sub-Saharan African patients: An observational study
REFNo: HS164ES

1. To determine demographic and clinical factors that determine individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care 2. To identify ethnic-specific genetic factors influencing individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care
UK 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Agnes Kiragga
ID:
Locating disengaged HIV positive women on Option B+ and ascertainment of outcomes among their infants
REFNo: HS175ES

1. To describe the pregnancy outcomes and HIV care status among women (and their exposed infants) who initiate Option B+ 2. To correct 6 week and 18 month estimates of MTCT through tracing of a random sample of HIV positive women who initiated Option B+ during pregnancy and disengaged from care. 3. To identify factors associated with HIV sero-positivity among infants born to women initiated on Option B+. 4. To establish the frequency of Multiclass Resistance among HIV positive infants born to women initiated on Option B+ 5. To estimate the proportion of disengaged women with viral failure and correct estimates of viral suppression (3 rd UN 90 goal) in the facilities.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
ANNET MAGOLO KISAKA
ID:
INFLUENCE OF ORGANISATIONAL CULTURE ON EMPLOYEE PERFORMANCE IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS155ES

1. To examine the extent to which organizational mission influences employee performance in public Universities in Uganda 2.To assess the extent to which consistency affects employee performance in public Universities in Uganda 3. To establish how employee involvement influences performance in public universities
Uganda 2018-04-04 2021-04-04 Social Science and Humanities Degree Award
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