Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Shevin  Jacob Thomas
ID: UNCST-2022-R010715
 The Sub-Saharan Africa ConsorTium for the Advancement of Innovative Research and Care in Sepsis (STAIRS) Cohort Study: A prospective multi-country network cohort of hospitalized sepsis patients
REFNo: HS5205ES

1. Describe the cohort’s epidemiologic, sociodemographic, clinical and management characteristics and to identify risk factors for disease severity and outcomes. 2. Characterize etiologic (and antimicrobial resistance patterns when relevant) and host response profiles and to evaluate their potential associations with clinical presentation, disease severity and outcome. 3. Determine the performance characteristics of innovative sepsis diagnostic platforms for pathogen identification, host response profiling and risk stratification in comparison with diagnostic testing available for usual care (including blood culture and existing sepsis scores).
USA 2025-01-31 7:59:00 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sabiti Makara
ID: UNCST-2024-R003444
 Crisis Emergencies, State Responses and ‘Windows’ of Corruption in Uganda
REFNo: SS3621ES

To implement bottom-up strategies for fighting corruption in emergency responses ,To examine the possibilities of grassroots actions and pressures that could have significant impacts on the fight against corruption,To establish the extent to which political considerations abate corruption with a focus on procurement and contracting during emergency crisis responses,To establish the gaps in regulatory frameworks that are opportunistically exploited by corrupt officials and their cronies to undermine anti-corruption efforts during emergency responses,Establish the actual costs of corruption and find out if the population is aware of its effects on public service delivery for the ordinary citizens,To examine the forms, practices, and patterns of corruption in emergency crisis responses in Uganda,Our main objective is to highlight and deepen our understanding of the extent which the risk of corruption intensifies during emergencies and to develop grassroots-based strategies to fight the vice.,
 Uganda 2025-01-31 7:50:39 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vincent Ferrer Bukenya
ID: UNCST-2024-R004868
 Examination of the relationships between refugee settlements and wood energy consumption: A case study of Bidibidi refugee settlement in northwest Uganda
REFNo: A527ES

This research will examine the relationships between refugee settlements and household access to sustainable wood energy. 1. To establish what forms the bulk of wood energy used by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 2. To assess wood energy consumption patterns in refugee and host communities in relation to the right to energy in Bidibidi Refugee Settlement in North-Western Uganda. 3. To examine how the refugee response framework provides for household access to wood energy by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 4. To determine the contribution of the refuge-host community relationships to households’ ability to sustainably access wood energy.
Uganda 2025-01-31 7:43:24 2028-01-31 Agricultural Sciences Non-Clinical Trial Degree Award
Ikuomola  Orire Emmanuel
ID: UNCST-2024-R003700
 EFFECT OF DIFFERENT FRACTIONS OF BRASSICA OLERACEA (COLLARD GREENS) ETHANOL EXTRACT ON CIMETIDINE INDUCED REPRODUCTIVE TOXICITY IN MALE WISTAR RATS.
REFNo: HS5192ES

i. Identify and quantify the constituents of crude aqueous leaf extract and fractions of Uganda collard green plant using gas chromatography mass spectrometry (GCMS);
ii. Evaluate the impact of crude aqueous leaf extract and fractions of Uganda collard greens on the relative weights of the testes, epididymis and anterior pituitary gland compared to body weight in male Wistar rats with cimetidine-induced reproductive toxicity by [specific date] male Wistar rats;
iii. Assess the effects of crude aqueous leaf extract and fractions of Uganda collard greens on sperm parameters, including motility, morphology, viability, agglutination, and total sperm count in Wistar rats with cimetidine-induced reproductive toxicity;
iv. Analyze the effect of crude aqueous leaf extract and fractions of Uganda collard greens on serum levels of steroid androgens (LH, FSH, Testosterone and antioxidant enzyme activities (catalase, Malondialdehyde, superoxide dismutase) in male Wistar rats with cimetidine-induced reproductive toxicity in male Wistar rats;
v. Examine the histological changes in the testes, epididymis, and anterior pituitary gland in male Wistar rats with cimetidine-induced reproductive toxicity following treatment with crude aqueous leaf extract and fractions of Uganda collard greens in male Wistar rats.

Nigeria 2025-01-31 7:40:27 2028-01-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Miriam  Amutuheire
ID: UNCST-2024-R001859
 Home-based tourism businesses and destinaion sustainability in Kabale Municiplaity, Kabale District, Uganda.
REFNo: SS3399ES

i.To assess the effect of the home-based tourism business operations on destination sustainability in Kabale municipality, Kabale District, Uganda.    
ii. To determine the influence of home-based tourism businesses competitiveness on destination sustainability in Kabale municipality, Kabale District, Uganda.  
iii. To establish the influence of government policies, impart on home-based tourism businesses that affect destination sustainability in Kabale municipality, Kabale District, Uganda.  
 Uganda 2025-01-31 7:38:46 2028-01-31 Social Science and Humanities Non-Clinical Trial Degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
 Effectiveness of Cognitive behaviour therapy for mental health problems among adult patients with type-II diabetes mellitus: a controlled study
REFNo: SS3413ES

a. To assess the effectiveness of CBT in treating mental health problems (psychological distress, depression, anxiety, quality of life, treatment adherence, hopelessness, pessimism) among adult patients with T2DM
b. To assess whether CBT affords a better control of glycaemia and the metabolic disturbances associated with T2DM.

 Uganda 2025-01-31 7:37:29 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Maternal immunization readiness network for the introduction of potential new maternal vaccines to prevent early childhood infectious diseases in Uganda
REFNo: HS5271ES

General objective:

To identify, characterize and support the platform, policy, and preparedness requirements for the introduction of potential new maternal vaccines to prevent infectious diseases in Uganda


Specific objectives:

1. To identify and implement approaches to assess health systems, facilities, and community readiness to introduce new maternal vaccines in Uganda
a. Identify and implement approaches to assess MI readiness for respiratory syncytial virus / Group B streptococcus vaccinations across the health system, including mapping key regulatory and financing requirements.
b. Map professional societies within the country and initiate country-based communities of practice for MI.
2. Generate and synthesize health economic evidence, in the Ugandan context, to support decision-making of respiratory syncytial virus / Group B streptococcus vaccination program adoption in low- and middle-income countries (LMICs).
3. Prospectively develop nationally tailored maternal vaccine demand strategies to support the uptake and sustained demand for existing and new maternal vaccines in Uganda.
4. Identify and effectively engage with diverse stakeholders, in a harmonized manner, to incorporate their views and expertise in the study’s outputs, to advance the maternal immunization readiness agenda in Uganda.

 Uganda 2025-01-31 7:35:56 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
 Improving School Management in a Low-Income Country: Experimental Evidence from Uganda
REFNo: SS3462ES

To evaluate the impact of the Inspect and Improve (I&I) program on student outcomes (learning, safeguarding, and inclusion) and school quality, focusing on both short-term and long-term effects.
 Uganda 2025-01-31 7:32:19 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Ochora
ID: UNCST-2021-R012659
 RUNYA-PHIV: Rural Uganda Neurocognitive Youth Assessment with Perinatally acquired HIV
REFNo: HS5534ES

To explore the differences in NeuroScreen performance among adolescents aged 12-19 years with Perinatally acquired HIV in urban (Kampala) vs rural areas (Mbarara).,To adapt NeuroScreen to assess neurocognition among Runyankole-speaking adolescents aged 12-19 years with Perinatally Acquired HIV ,
 Uganda 2025-01-31 7:31:16 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Kyobe
ID: UNCST-2019-R000108
 DSpace – Ethical Implications of Pediatric EHR Use in Medical Research in Uganda and Botswana
REFNo: HS5301ES

1. Analyze the ELP issues raised by the use of pediatric EHR in medical research in Uganda and Botswana
2. Determine/analyze the implications of data linkage on participant consent and privacy
 Uganda 2025-01-31 7:27:19 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Maleka
ID: UNCST-2024-R015301
 Sex differences in alcohol consumption and its impact on vulnerability and susceptibility to develop dementia in rural Uganda.
REFNo: SS3477ES

1. To determine the patterns of alcohol consumption among men and women aged 60 years and above in Ibanda and Lira districts.
2. To assess the association between alcohol consumption and cognitive impairment among men and women in rural Uganda
3. To determine the socio-cultural factors that contribute to gender differences in the vulnerability to alcohol-related cognitive impairment in Ibanda and Lira districts.

 Uganda 2025-01-31 7:24:38 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
john semuwemba
ID: UNCST-2022-R015225
 Association between prenatal alcohol exposure and Cognitive and Behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
REFNo: HS5331ES

General Objective.
To determine the prevalence of prenatal alcohol exposure and the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
Specific Objectives.
1 To determine the prevalence of prenatal alcohol exposure in rural Rwampara and Lira districts.
2 To determine the prevalence of cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
3 To determine the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.

Uganda 2025-01-31 7:22:50 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mukunya
ID: UNCST-2022-R010707
 A phase III, randomized, open-label, clinical trial to evaluate the safety and efficacy of emollient therapy for very low birthweight infants (<1500g) in Uganda in promoting survival, health, growth and development compared to no emollient treatment
REFNo: HS5338ES

To evaluate the efficacy of emollient therapy with SSO – compared to standard care without use of emollients – among hospitalised very low birth weight (VLBW, <1500g) infants in Uganda on: the rate of in-hospital mortality, serious infections, hypothermia, growth, intraventricular haemorrhage, and skin condition; maternal depression and anxiety; maternal and neonatal interaction; infant growth and neurodevelopment at 12 month corrected age (chronological age reduced by the number of weeks born before 40 weeks of gestation); and infant mortality.
Uganda 2025-01-31 7:21:53 2028-01-31 Medical and Health Sciences Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
 Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study.
REFNo: HS5389ES

To evaluate the impact of a structured antimicrobial review on rates of antimicrobial density, redundancy and associated indicators of antimicrobial utilisation.,To determine whether a structured antimicrobial review can be implemented in LMIC ICUs,
 UK 2025-01-31 7:20:18 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WAYENGERA Misaki
ID: UNCST-2024-R002503
 DECIPHERING HOST GENETICS AND VIRAL DETERMINANTS OF MPOX PATHOGENESIS IN THE DEMOCRATIC REPUBLIC OF CONGO AND THE NEIGHBORING COUNTRIES (DECIPHER-MPOX)
REFNo: HS5409ES

The goal of the DECIPHER-MPOX project is to determine the host genetic and viral determinants of mpox in Uganda and in the Democratic Republic of Congo (DRC) among survivors of mpox and their house hold contacts ,
 Uganda 2025-01-31 7:18:46 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Tumwine Bwagiro
ID: UNCST-2024-R004504
 Promotion of integrated and sustainable community interventions to prevent GBV and strengthen Adolescent Sexual Reproductive health and rights. A realistic evaluation protocal from Uganda
REFNo: SS3540ES

The overall objective is to promote integrated and sustainable community interventions to prevent GBV and Strengthen SRHR,
 Uganda 2025-01-31 7:17:15 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Kanyike Marvin
ID: UNCST-2020-R014554
 Optimizing Hypertension and Type 2 Diabetes Mellitus Management among People Living with HIV using a HEARTS-Based Strategy in Eastern Uganda: A Feasibility and Preliminary Effectiveness Study.
REFNo: HS5399ES

To identify the barriers and facilitators to the optimal management of HTN and T2DM among PLHIV at Mbale Regional Referral Hospital in Eastern Uganda.

To develop and implement a HEARTS-based strategy for optimized management of HTN and T2DM among PLHIV at Mbale Regional Referral Hospital in Eastern Uganda.

To determine the feasibility, acceptability, and preliminary effectiveness of the HEARTS-based strategy in optimizing the management of HTN and DM among PLHIV at the Mbale Regional Referral Hospital in Eastern Uganda.

To evaluate the reach, adoption, implementation, and maintenance of the HEARTS-based strategy for optimizing hypertension and diabetes mellitus management among PLHIV at Mbale Regional Referral Hospital.

 Uganda 2025-01-31 7:16:22 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mordecai Tayebwa
ID: UNCST-2024-R002437
 Expanded Strengthening of Makerere University's Research Administration Capacity Program (E-SMAC)
REFNo: HS5531ES

Test knowledge and skills change over time of faculty prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff and faculty prior to and following the SOP trainings and implementation activities ,
 Uganda 2025-01-30 18:30:42 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Evidence Synthesis To Inform Strengthening Medical Oxygen Systems in low- and middle-income countries”. (ESTISMOS)
REFNo: HS5437ES

10. To assess the implementation outcomes and impact of the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria,9. To determine the health facility readiness, also known as “change valence”, to implement the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria.,8. To assess the capability (real and perceived) of the selected health facilities, also known as, “change efficacy” to implement the Oxygen-as-a- service intervention in Uganda. ,7. To examine the coordination mechanisms at national, district, health facility levels that facilitate availability of medical oxygen at health facilities.,6. To examine the stakeholder positions, interests, and influences along the medical oxygen supply chain on access to medical oxygen at health facilities.,5. To characterize processes and tools for information flow and management for medical oxygen and oxygen related equipment.,4. To map the medical oxygen supply chain system and explore the nodes and links from the medical oxygen sources to health facilities where it is needed.,3. To synthesize the extent to which healthcare packages have incorporated oxygen therapy solutions to promote their adoption, scale up and sustainability. ,2. To summarize the implementation outcomes of oxygen therapy solutions from published intervention studies in LMICs. ,1. To synthesize determinants of implementation outcomes of oxygen therapy solutions in low- and middle-income countries.,
 Uganda 2025-01-30 18:27:31 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adityavarman Mehta Umesh
ID: UNCST-2024-R002841
 The Role of Global Health Diplomacy in Achieving Peacebuilding in Post-Conflict Northern Uganda
REFNo: SS3590ES

In this context, the thesis will examine the use of global health diplomacy, which aims to bridge the disciplines of public health, international relations, and public policy, as a peacebuilding instrument in northern Uganda. With numerous health initiatives such as those that addressed the increasing incidence of HIV/AIDS and Ebola during the civil war between 1986 and 2006, and psychosocial programs following the conclusion of the war, there is scope to determine whether these health initiatives contributed to the cessation of violence and ultimately, peacebuilding. This thesis will arrive at this determination by assessing if health initiatives implemented in northern Uganda during and after the conflict fostered social cohesion and afforded Ugandans, particularly women, agency or the opportunities to follow through on their choices. The twenty-year conflict in northern Uganda provides an effective context for this thesis because the violence was largely a product of its political and social history (Kustenbauder, 2010). The violence had ethnic and religious dimensions as well, with academic literature on the subject suggesting that the largest rebel group fighting the national army, the Lord’s Resistance Army, viewed its struggle against the government of Uganda as a divine cause, which was guided by God through its leader, Joseph Kony (Van Acker, 2004). Against this political and historical backdrop, this thesis will aim to determine if global health diplomacy was able to, in whole or in parts, achieve peacebuilding objectives in northern Uganda.
Uganda 2025-01-30 18:24:54 2028-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
Hilary Muheezangango
ID: UNCST-2024-R002492
 GOVERNANCE PRACTICES AND ECONOMIC SECURITY IN PINEAPPLE VALUE CHAIN COMMUNITIES IN SELECTED DISTRICTS; CENTRAL UGANDA.
REFNo: SS3466ES

Main Objective: To examine the relationship between governance practices, and economic security of Pineapple Value Chain Communities in Central Uganda.

Specific objectives
i. To examine the contribution of shared goals among stakeholders on the economic security of Pineapple Value Chain Communities in the Districts of Luweero, Kayunga and Mukono; Central Uganda.
ii. To examine the relationship between shared roles and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iii. To analyze the relationship between shared knowledge and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iv. To assess the mediating effect of work environment on the relationship between governance practices and economic security in Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.

 Uganda 2025-01-24 14:40:20 2028-01-24 Social Science and Humanities Non-Clinical Trial Degree Award
Norah Babirye
ID: UNCST-2024-R015349
 Optimising Indigenous Food Consumption for Improved Metabolic Health among Adults in Uganda.
REFNo: A549ES

1. To evaluate indigenous vegetable and fruit consumption patterns among adults in Wakiso district, Uganda.
2. To identify the sources of indigenous vegetable and fruit consumed among adults in Wakiso district, Uganda.
3. To document the cardiometabolic health profile of adults in Wakiso district, Uganda.

Uganda 2025-01-24 14:38:11 2028-01-24 Agricultural Sciences Non-Clinical Trial Degree Award
Laura Twubahe
ID: UNCST-2024-R002589
 Nutritional, Physical-chemical, and Microbiological changes in the properties of cooking oil and street-vended deep-fried foods in Wakiso District, Central Uganda: A case study of Kira Municipality.
REFNo: HS5308ES

General objective
The general objective of this study is to evaluate the physical-chemical changes in cooking oil and the Microbiological safety of street vended deep fried foods in Kira Municipality, Wakiso District, Uganda.

Specific Objectives
The specific objectives of the study are to;
1. Assess the changes in the physical-chemical properties including trans fatty acids of cooking oil used by street vendors of Rolex and deep-fried chicken in Kira Municipality.
2. Assess the microbiological safety of street vended rolex and deep-fried chicken in Kira municipality.
3. Assess the knowledge, attitudes, and practices of street vendors of rolex and deep-fried chicken in Kira Municipality.

 Uganda 2025-01-22 9:56:29 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Robertson Turyamwijuka
ID: UNCST-2024-R015990
 A sustainable Public procurement implementation framework for Public Sector Entities in Uganda.
REFNo: SS3597ES

3.1 PRIMARY OBJECTIVE The primary objective of this study seeks to develop and propose a sustainable public procurement implementation framework that will guide Ugandan public entities on how to enhance sustainable public procurement performance through the effective implementation of sustainable public procurement practices and approaches. This will enable these public entities to also address the unique challenges and opportunities they face, with the aim to enhance efficiency, accountability, and sustainability in public procurement processes. The accomplishment of the ensuing secondary objectives will enable this. 3.2 SECONDARY OBJECTIVES OF THE STUDY The following secondary objectives have been determined in order to fulfil the study's main goal: 3.2.1 To identify the drivers influencing the implementation of sustainable public procurement in public sector entities in Uganda. 3.2.2 To identify the sustainable public procurement practices currently implemented among Ugandan public sector entities. 3.2.3 To identify the challenges and their consequences faced by Ugandan public sector entities when implementing sustainable public procurement. 3.2.4 To identify sustainable public procurement approaches within public sector entities in Uganda. 3.2.5 To determine the influence of sustainable public procurement drivers on sustainable public procurement performance. 3.2.6 To determine the influence of the drivers of sustainable public procurement on sustainable public procurement approaches. 3.2.7 To assess the influence of sustainable public procurement drivers on the adoption of sustainable public procurement practices. 3.2.8 To assess the influence of sustainable public procurement approaches on sustainable public procurement practices. 3.2.9 To assess the influence of sustainable public procurement practices on sustainable public procurement performance. 3.2.10 To assess the influence of sustainable public procurement approaches on sustainable public procurement performance. 3.2.11 To assess how sustainable public procurement approaches, in Ugandan public sector organizations, mediate the relationship between sustainable public procurement drivers and sustainable public procurement performance. 3.2.12 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement drivers and sustainable public procurement performance in Ugandan government agencies. 3.2.13 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement approaches and sustainable public procurement performance within public sector entities in Uganda. 3.2.14 To provide a conceptual framework for Ugandan public sector entities to embrace sustainable public procurement.
Uganda 2025-01-22 17:09:13 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Adoch
ID: UNCST-2024-R003825
 Land Conflicts and Livelihood Nexus in Gulu City, Northern Uganda
REFNo: SS3531ES

To assess the attitude and perceptions of inhabitants on effectiveness of land conflict resolution mechanisms in Gulu city,To assess the effects of land conflicts on livelihood capitals of inhabitants in Gulu city,To examine the drivers of land conflict among inhabitants in Gulu city,To determine the nature of land conflicts among inhabitants in Gulu city,The study aims to examine the nature and extent of land conflicts, explore how these conflicts affect the livelihood assets of the local population, and assess the effectiveness of existing mechanisms for conflict resolution. This study seeks to provide insights that can inform policy, and interventions aimed at improving land management and enhancing the livelihoods of the affected communities.,
 Uganda 2025-01-22 17:07:20 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Evaluating the performance, feasibility, acceptability and impact of treatment-decision algorithms for pulmonary tuberculosis in children in Uganda and their unmet social needs;TDA4Child
REFNo: HS5390ES

(i) To compare the diagnostic accuracy of the study TDAs with the Uganda national algorithm for the diagnosis of TB in children
(ii) To compare adults and children TB notifications before and after study initiation;
(iii) To describe the caregiver’s (parents or guardians) acceptability in introducing TB treatment based on the TDA outcome
(iv) To describe healthcare workers’ (HCWs) experience, acceptability of and satisfaction with and feasibility of algorithm the TDAs’ implementation
(v) To describe the unmet social needs, social protection coverage, and dissaving among children under 10 years old being evaluated for pulmonary TB and their households in Uganda.
Uganda 2025-01-22 17:04:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Validation of the Quality of Dying and Death-Revised Global Version scale in Uganda
REFNo: SS3429ES

3) To assess the relationship between quality of death and dying and grief and bereavement symptoms reported by caregivers,2) To determine the reliability of the QODD-RGV,1) To examine face and content validity of the QODD-RGV index.,The main objective of this study is to undertake a psychometric evaluation of the Quality of Death and Dying Index. ,
 Uganda 2025-01-22 16:56:37 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Clinical Performance Evaluation of Kwiq-Test HIV-1/2 (Whole Blood/Serum/ Plasma): Diagnostic sensitivity & diagnostic specificity, specimen equivalence, Anticoagulant equivalence and qualification of usability
REFNo: HS5368ES

The objectives of this study are:
1. To establish the diagnostic sensitivity and diagnostic specificity of the Kwiq HIV-1/2 test (Serum/Plasma/wholeblood) in plasma samples according to the WHO TSS-1 Part 2.1
2. To demonstrate the equivalence of serum, plasma (EDTA-K2), venous whole blood (EDTA-K2) and fingerprick whole blood collected from HIV positive patients according to WHO TSS-1 Part 1: 1.1.1.
3. To demonstrate anticoagulant equivalence of serum, venous whole blood (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin), plasma (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin) and fingerprick whole blood
4. To demonstrate the usability of this rapid diagnostic test when performed by the intended users. It will be assessed whether the intended users comprehend all key messages from labelling and packaging (i.e. label comprehension study) and whether they can correctly interpret pre-determined test results (i.e. result interpretation study).
To meet all the requirements as set out in the WHO TSS-1study will be conducted in Uganda

 Uganda 2025-01-22 16:53:12 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 Developing Better Control Together, a multi-faceted patient-support group for patients with hypertension in Uganda
REFNo: HS5309ES

We propose to develop a multi-faceted patient-support group for patients living with HTN in rural Uganda using an iterative approach that is tailored to the local context. We will adapt several evidence-based interventions for patient-support groups from the HIV experience to develop a comprehensive intervention for patients with HTN by including aspects of disease education, social support, financial activities, and bulk purchasing of HTN medications.
 USA 2025-01-22 16:51:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Rwankangi
ID: UNCST-2024-R016056
 Solar-Powered Irrigation Schemes for Smallholder Farmers in Uganda: Assessing Impact and Sustainability
REFNo: SIR452ES

1. To examine the impact of adopting solar-powered irrigation systems on crop
yields in horticulture among smallholder farmers in eastern Uganda.

2. To examine how farmers’ knowledge and skills in operating and maintaining
solar irrigation systems influence the adoption of solar-powered irrigation
technology among smallholder farmers.

3. To analyze the effect of stakeholder engagement on the adoption of solar-
powered irrigation technologies among smallholder farmers.

4.To assess how the Ugandan Government’s policy frameworks influence, the
adoption of solar-powered irrigation technology among smallholder farmers.

 Uganda 2025-01-22 16:49:32 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 Functional Role, Temporal Dynamics, and Protective Impact of IgA on Clinical Outcomes in Uncomplicated Plasmodium falciparum Malaria
REFNo: HS5353ES

General Objective
To investigate the functional role, temporal dynamics, and protective impact of IgA on clinical outcomes in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda.
Specific Objectives
1. To quantify the functional activity of serum IgA antibodies in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda, by measuring the percentage reduction in hepatocyte infection, the inhibition of merozoite invasion of erythrocytes, and the level of neutrophil activation through oxidative burst and cytokine release.
2. To characterize the temporal dynamics and persistence of IgA responses in adult patients with uncomplicated malaria in the greater Kampala region over a 42-day follow-up period, by measuring peak IgA levels (C_max), time to peak level (T_max), rate of decline (IgA half-life), and area under the curve (AUC).
3. To evaluate the association between serum IgA levels and clinical outcomes in adult patients with uncomplicated malaria in the greater Kampala region, by assessing symptom resolution time and parasite clearance time.
4. To determine the correlation between IgA levels and complement activation, as well as their association with pro-inflammatory or regulatory cytokines during and after Plasmodium falciparum infection in adult patients with uncomplicated malaria in the greater Kampala region, Uganda.

 Uganda 2025-01-22 16:47:42 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dina Nabasumba
ID: UNCST-2023-R006504
 Crop production dynamics and vulnerability to food insecurity in the face of climate variability: A case of smallholder farmers in south-western Uganda
REFNo: A524ES

4. To classify the extent and factors controlling the influence of climate variability on vulnerability to food insecurity among smallholder farmers in south-western Uganda,3. To determine the influence of spatial-temporal rainfall variability on adoption patterns of land-based climate smart agricultural practices in seasonal cropping systems of smallholder farmers in south-western Uganda ,2. To establish the relationship between smallholder farmers’ knowledge, attitudes and adoption of climate smart agricultural practices in south-western Uganda,1. To assess smallholder farmers’ perceptions of climate variability and the extent to which it has altered crop selection and cultivation patterns in south-western Uganda,To establish the influence of climate variability on the crop production systems and vulnerability to food insecurity among smallholder farmers in south-western Uganda,
 Uganda 2025-01-22 16:46:28 2028-01-22 Agricultural Sciences Non-Clinical Trial Degree Award
Chikadibia Uche Kalu Awa
ID: UNCST-2024-R003818
 OPTIMIZATION OF MIX DESIGN FOR STRUCTURAL LIGHTWEIGHT CONCRETE (SLWC) WITH ARTIFICIAL AGGREGATES USING RESPONSE SURFACE METHODOLOGY
REFNo: SIR344ES

1. To produce and characterize artificial aggregates from polyethylene terephthalate plastic waste.
2. To design experimental mixture proportions for S.L.W.C. using mathematically independent variable (factorial) approach.
3. To evaluate the performance of S.L.W.C. regarding density, splitting tensile strength, compressive strength, workability, and durability.
4. To apply response surface methodology for the analysis of the obtained results to derive model equations for each performance criteria.
5. To optimize (S.L.W.C.) using desirability function.
6. To carry out microstructural analysis of the specimens.

 Nigeria 2025-01-22 16:45:23 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
SIMON MUCHURO
ID: UNCST-2024-R003624
 Estimation of TB notification rates among healthcare workers in 2023 and assessment of associated healthcare worker and health facility characteristics
REFNo: HS5200ES

Primary objective:
1. To establish the TB notification rates among healthcare workers
2. To establish the risk factors associated with TB disease
Secondary objectives:
3. To determine TB treatment outcomes among healthcare workers started on drug sensitive TB treatment from 1st January to 31st December 20
 Uganda 2025-01-22 16:44:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Muwonge Ssajjabbi
ID: UNCST-2023-R007179
 AN INVESTIGATION INTO THE IMPACT OF TELEMEDICINE ON PATIENT OUTCOMES IN KAMPALA DISTRICT. A CASE OF RUBAGA DIVISION
REFNo: HS4901ES

iii. To investigate the extent to which telemedicine improves patient satisfaction for patients in Lubaga division. ,ii. To assess the impact of telemedicine on accessibility of health care services for patients in Lubaga division. ,i. To identify the barriers and facilitators of telemedicine adoption and how they impact patient outcomes in Lubaga division. ,To investigate the impact of telemedicine on patient outcomes in Kampala district, with emphasis on Lubaga division so as to improve the quality of health-care service delivery.,
 Uganda 2025-01-22 16:38:30 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
ROSE AKULLO
ID: UNCST-2024-R005155
 LEADERSHIP BEHAVIOR IN MANAGEMENT OF CURRICULUM CHANGES IN THE LOWER SECONDARY SCHOOLS IN KARAMOJA REGION, NORTH EASTERN UGANDA.
REFNo: SS3120ES

5. Determine the mediating effect of organizational climate on the relationship between leadership behaviours and curriculum change management in the lower secondary curriculum,4. To assess the impact of leadership behaviour on the level of teacher support for curriculum change management in lower secondary schools in the Karamoja Region, Uganda.,3. Establish the effect of change-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja ,2. Assess the effect of task-oriented leadership behaviours on management of curriculum changes in lower secondary schools in the Karamoja Region, Uganda.,1.Examine the effect of relation-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja,To investigate the effect of leadership behaviors on management of curriculum changes in secondary schools in Karamoja region, North Eastern Uganda.,
 Uganda 2025-01-22 16:33:52 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
BONIFACE OJOK
ID: UNCST-2023-R006075
 Lok Ber Bedo Study: Storytelling with young people affected by conflict in Acholi sub-region, northern Uganda
REFNo: SS3437ES

1. General objective: The proposed project seeks to engage groups of young people affected by conflict in Acholi sub-region to explore the extent to which storytelling can be harnessed to promote shared understanding of the wholesome character of ber bedo (Acholi meaning 'wellbeing) and collective action to advance ber bedo.

2. Specific objectives
(1) To explore conflict affected young people’s understanding of ber bedo and practice of storytelling in Acholi sub-region.
(2) To identify challenges to ber bedo among young people affected by conflict in Acholi sub-region and to explore existing and potential strategies to address these.
(3) To assess to what extent the 'lok ber bedo' (Acholi meaning 'let's talk well-being') storytelling approach can be transformational, in its various dimensions, for young people affected by conflict in Acholi sub-region.
Uganda 2025-01-22 16:24:55 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nabusige Gesa Jean Brenda
ID: UNCST-2024-R005397
 Acaricide exposure and associated genotoxicity in farmers of the cattle corridor: a case study of Kiruhura district
REFNo: HS5250ES

To determine oxidative stress, inflammatory and genotoxicity outcomes among pesticide exposed farmers and establish their relationship with pesticide exposure.,To quantify residues of selected pesticides in raw cows milk and open well water, as well as human and animal serum and determine factors associated with these residue levels. ,To assess Knowledge, Attitudes, and Practices towards pesticide use and factors associated with variations therewith among farmers.,To investigate farmers Knowledge, Attitudes and Practices towards pesticide use, farm ecosystem exposure, associated outcomes to human health and genotoxicity among pesticide exposed farmers.,
 Uganda 2025-01-22 15:51:36 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Elly Atuhumuza
ID: UNCST-2024-R002706
 Assessing Effectiveness of Interpersonal Group Therapy for Depression on Academic Performance in Ugandan Schools
REFNo: SS3249ES

To describe the feasibility and acceptability of implementing IPT-G within the school setting,To determine the effects of IPT-G on the academic performance of students by measuring improvements in grades, attendance, and overall academic engagement.,To determine the effects of Interpersonal Group Therapy (IPT-G) on reducing depressive symptoms among school-aged adolescents in Uganda. ,The general objective is to evaluate the effectiveness of Interpersonal Group Therapy (IPT-G) in improving the mental health and academic performance of students in Ugandan schools.,
 Uganda 2025-01-22 15:47:24 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richardson Mafigiri
ID: UNCST-2024-R003907
 HEALTH WORKERS PRACTICES AND PERFORMANCE OF HEALTHCARE PROJECTS IN KAYUNGA DISTRICT, UGANDA
REFNo: SS3194ES

iv. To examine the relationship between policy support and performance of health projects in Kayunga district,iii. To establish practical strategies to improve Performance of health projects in Kayunga District ,ii. To examine the effect of vaccine management by health workers on Performance of health projects in Kayunga District.,i. To determine the effect of surveillance practices by health workers on Performance of health projects in Kayunga District.,The purpose of the study will be to assess the effect of health workers’ practices on performance of health projects in Uganda,
 Uganda 2025-01-22 15:42:36 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Juma Said Tusubila
ID: UNCST-2024-R005319
 Using Photovoice to examine the burden and experiences of refugee caretakers of children with special health care needs in Rhino Camp refugee settlement in West Nile, Uganda
REFNo: HS5441ES

● To explore the physical, emotional, and financial challenges (burden) faced by refugee caretakers of CSHCN in Rhino Camp Refugee Settlement, West Nile ● To understand the coping mechanisms and resilience of refugee caretakers in of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile. ● To generate insights on the support systems, barriers, and facilitators to improve the well-being of caretakers of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile.
Uganda 2025-01-22 15:08:17 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
 ‘5 Rs to Rescue’ A quality improvement initiative with a cluster trial evaluation and embedded process evaluation
REFNo: HS5020ES

To evaluate the effect of the QI intervention on: 1. 30 day in-hospital mortality. 2. Duration of hospital stay.,To evaluate whether implementation of the ‘5 Rs to Rescue’ quality improvement intervention increases surveillance for patients at risk of ‘failure to rescue’ after surgery in hospitals in Africa.,
 UK 2025-01-22 12:30:25 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Immaculate  Nankya Lillian
ID: UNCST-2020-R014784
 Interplay between Estrogen, immune activation and HIV persistence during pregnancy
REFNo: SS3319ES

To characterize the clonal dynamics and diversity within the circulating latent reservoir in pregnant women on ART who are experiencing low-level viremia, viral blips, and persistently non-suppressed virus. ,To measure fluctuations in inflammation and immune activation markers, estrogen, and reservoir dynamics in women during pregnancy. , The main goal of this protocol is to understand the interplay between estrogen, markers of immune activation and the reservoir dynamics among pregnant women.,
 Uganda 2025-01-22 11:58:29 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
 Comparing in-person versus virtual postoperative review appointments for children following guided growth surgery at CORSU Hospital, Uganda
REFNo: HS5268ES

Study Objectives
Primary objectives
To compare the show-rates of in-person versus virtual/telehealth post-operative review appointments for children following guided growth surgery at CoRSU Hospital

Secondary objectives.
1.To compare parental satisfaction of in-person versus virtual appointments
2.To determine the factors that facilitate in-person and virtual appointments following guided growth surgery.
3.To compare the rate of post-operative complications following in-person follow-up versus virtual follow-up
 Uganda 2025-01-22 10:12:27 2028-01-22 Medical and Health Sciences Clinical Trial Non-degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 GENERATING LOCAL DATA ON HPV VACCINATION IMPACT AND TRAINING NEEDS AT THE LEVEL OF VACCINE IMPLEMENTERS – A FEASIBILITY STUDY
REFNo: HS5219ES

1) generate local data on HPV vaccine induced immune response and HPV infection prevalence using first-void urine (FVU) in Uganda and assess feasibility of conducting such studies, 2) assess knowledge and training gaps among HCWs in Uganda and standardize HPV vaccine training barometer survey,
Uganda 2025-01-22 10:09:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MUSANA SAMSON ISRAEL
ID: UNCST-2024-R016481
 RELIGIOUS MISSION FIELD RIVALRIES AND ITS IMPACT ON CHRISTIAN-MUSLIM PEACEFUL COEXISTENCE IN MBALE CITY, UGANDA
REFNo: SS3541ES

1) to investigate the root causes of religious mission field rivalries affecting Christian-Muslim peaceful coexistence. 2) to establish Christian and Muslim missionary methods being utilised in the
mission field; and 3) to ascertain the impact of Christian and Muslim missionary outreach
practices.
 Uganda 2025-01-10 12:29:51 2028-01-10 Social Science and Humanities Non-Clinical Trial Degree Award
Venantius Bbaale Kirwana Bbaale
ID: UNCST-2024-R002370
 Behind the Scenes: Young women and gender-based inequities in Africa’s Creative Sector -Uganda research project
REFNo: SS3483ES

iii. Provide evidence-based recommendations and best practices for key stakeholders that can support gender equity in Uganda\'s creative industries and workplaces.,ii. Map the Creative Sector in Uganda to understand its organization in terms of stakeholders, policies, potential, remuneration systems, accessibility to different categories of youth, challenges, conduct codes, job creation opportunities, funding, education, training, products, and services.,i. To generate and disseminate evidence on the nature, dynamics, and implications of gender-based inequities faced by young female creatives in Uganda and other countries in the project.,
 Uganda 2025-01-10 12:12:15 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Justine Namuli Diana
ID: UNCST-2021-R011844
 ENHANCING COMPREHENSION OF INFORMED CONSENT IN RESEARCH INVOLVING PATIENTS WITH PSYCHOTIC DISORDERS USING AUDIO-VISUAL AIDS
REFNo: HS5358ES

To evaluate the comprehension of informed consent, identify key factors that are associated with comprehension of consent, determine the feasibility, acceptability, and preliminary effectiveness of audio-visual aids on enhancing the comprehension of consent information during the consenting process in research involving individuals with psychotic disorders
 Uganda 2025-01-10 12:00:57 2028-01-10 Medical and Health Sciences Clinical Trial Degree Award
Baguma Deus Bagambana
ID: UNCST-2024-R002898
 AGRONOMIC AND UTILIZATION POTENTIAL OF COCOYAM IN SOUTH WESTERN HIGHLANDS AGRO-ECOLOGICAL ZONE OF UGANDA
REFNo: NS888ES

1. To establish cocoyam production practices, constraints and trait preferences in the south western highlands agroecological zone of Uganda.
2. To establish the facilitators and barriers of cocoyam utilization by value chain end users in south western highlands agroecological zone of Uganda
3. To determine edaphoclimatic suitability of cocoyam production in the south western highlands agroecological zone of Uganda
4. To establish the feasibility of utilisation of cocoyam flour for production of cookies in south western highlands agroecological zone of Uganda

Uganda 2025-01-10 11:58:50 2028-01-10 Natural Sciences Non-Clinical Trial Degree Award
BAINA NAKANWAGI
ID: UNCST-2024-R002838
 Financial Literacy and performance of Micro and small businesses owned by muslim women in Mbarara city,Uganda
REFNo: SS3493ES

i) To assess the effect of Islamic finance principles on performance of micro and small businesses owned by muslim women in Mbarara City
ii) To evaluate the impact of debt management on performance micro and small businesses owned by muslim women in Mbarara city
iii)To evaluate the impact of finance planning and budgeting on performance micro and small businesses owned by muslim women in Mbarara city
iv) To establish the moderating effect of access to finance on the relationship between financial literacy and performance of micro and small enterprise owned by muslim women in Mbarara city
1.5 Research Questions
i) What is the effect of Islamic finance principles on the performance of micro and small businesses owned by Muslim women in Mbarara City?
ii) What is the impact of debt management on the performance of micro and small businesses owned by Muslim women in Mbarara City?
iii) How does financial planning and budgeting affect the performance of micro and small businesses owned by Muslim women in Mbarara City?
iv) What is the moderating effect of access to finance on the relationship between financial literacy and the performance of micro and small enterprises owned by Muslim women in Mbarara City?

 Uganda 2025-01-10 11:57:43 2028-01-10 Social Science and Humanities Non-Clinical Trial Degree Award
Ali Ndiwalana
ID: UNCST-2024-R015333
 Evaluation of UNICEF’s contribution towards addressing equitable access to quality, inclusive education for vulnerable children and adolescents in Uganda 2021-2024
REFNo: SS3478ES

The evaluation that will assess the relevance and effectiveness of UNICEF's contributions towards achieving the goals set for the BEAD
programme under the CPD 2021-2025. The evaluation's findings are expected to guide the design of UNICEF's future learning and skilling programs in Uganda
 Uganda 2025-01-10 11:56:23 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jackline  Akello
ID: UNCST-2023-R005827
 Sickle cell disease in pregnancy: Experiences in provision and access to care and adverse pregnancy outcomes at Mbale and Kawempe Referral Hospitals
REFNo: HS5315ES

4.To explore health providers experiences in providing care to pregnant women with SCD at Mbale and Kawempe referral hospitals. ,To explore experiences of pregnant women with SCD in accessing health care at Kawempe and Mbale referral Hospitals. ,2.To determine risk factors for adverse fetal outcomes among pregnant women with SCD at Mbale and Kawempe Referral Hospitals,To determine risk factors for adverse maternal outcomes among pregnant women with SCD at Mbale and Kawempe Referral Hospitals ,The general objective is to determine the adverse maternal and fetal outcomes associated with pregnancies complicated by SCD and explore experiences in access and provision of care at Mbale and Kawempe Referral Hospitals. ,
 Uganda 2025-01-10 11:54:49 2028-01-10 Medical and Health Sciences Non-Clinical Trial Degree Award
BABTUNDE SAMUEL ADEBAYO
ID: UNCST-2024-R002460
 The Endline Evaluation of CorpsAfrica's Community Development Interventions in Uganda (FY23/24)
REFNo: SS3428ES

The objective of the Endline Evaluation of CorpsAfrica's Community Development Interventions in Uganda (FY23/24) is to assess the impact, effectiveness, and sustainability of interventions implemented by CorpsAfrica volunteers across four districts—Buikwe, Lyantonde, Mpigi, and Kabarole. The evaluation aims to measure changes in community development outcomes, assess improvements in livelihoods, and document the role of volunteers in addressing the needs of these communities. Furthermore, the evaluation will capture lessons learned, identify best practices, explore community acceptance, and assess stakeholder contributions, ultimately providing valuable insights for improving and scaling similar community-led development initiatives in Uganda and beyond.
 Nigeria 2025-01-10 11:53:04 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
 HIP SURVEILLANCE IN PAEDIATRIC PATIENTS WITH CEREBRAL PALSY AT CoRSU REHABILITATION HOSPITAL
REFNo: HS5220ES

Primary objective
1. To assess the feasibility of implementing a hip surveillance program in detecting early signs of displacement among cerebral palsy patients attending CoRSU hospital in 2024-2025
2. To determine the incidence of hip dislocation in patients with cerebral palsy seen at CoRSU hospital in 2024-2025
Secondary objectives
1. To assess changes in the QOL of life of children after joining the hip surveillance program on hip displacement among children with cerebral palsy seen at CoRSU hospital in 2024-2025

2. To develop a standard for frequency of pelvic x-rays for children with cerebral palsy seen at CoRSU hospital in 2024-2025

3. To evaluate the benefits and complications of early intervention measures on reducing hip displacement cerebral palsy seen at CoRSU hospital in 2024-2025

 Uganda 2025-01-10 11:51:15 2028-01-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Sub-Study D – Evaluation of Point-of-Care C-reactive Protein Assay Performed on the EnLiSense Rapid ElectroAnalytical Device (READ) Platform Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS5172ES

To validate the CRP assay performed on the READ platform by comparing it to a point-of-care conventional CRP assay previously cleared by the United States Food and Drug Administration (FDA). The results from this substudy are intended to be used for a FDA 510(k) submission for the EnLiSense READ device and CRP assay
 Uganda 2025-01-10 11:49:48 2028-01-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ferdinand Nduwayo
ID: UNCST-2024-R004506
 Development of Comprehensive Seismic Design Guidelines for Earthquake Resistant Design of Buildings in Uganda
REFNo: SIR390ES

(e) To develop comprehensive national structural design guidelines based on modern seismic design codes, aimed at providing engineering practitioners with practical seismic risk mitigation techniques; subsequently leading to sustainable growth and development,(d) To derive spectral displacement, elastic and design pseudo-acceleration spectra representing seismic action in the horizontal direction for key building typologies located in major cities in Uganda,(c) To develop reliable bespoke building exposure models for risk calculations by gathering data on building stock taxonomies and occupancy types,(b) To perform a stochastic event-based probabilistic seismic hazard analysis for Uganda which relies on the available data collected on the seismicity, geology and tectonics of the country,(a) To compile Uganda historical and instrumental earthquake catalogues required for homogenisation, removal of non-Poissonian events and completeness analyses,The main objective of this research proposal is to develop comprehensive earthquake-resistant building design guidelines specifically tailored for Uganda\'s unique geological, seismo-tectonic conditions and available construction materials. These guidelines will facilitate the construction of buildings that can withstand earthquakes, thereby reducing the potential for damage and casualties during seismic events.,
 Burundi 2025-01-10 11:48:15 2028-01-10 Engineering and Technology Non-Clinical Trial Non-degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
 A One Health Survey of AMR and farming practices that drive Antimicrobial Resistance at Selected Animal-Human-environment Interface in Uganda
REFNo: A539ES

General Objective: To build capacity for antimicrobial resistance (AMR) surveillance and AMR stewardship using a One Health approach.

Specific Objectives:
1. To isolate the AMR resistant E coli and Salmonella from slaughtered chicken, slaughtered cattle and the environment. 2. To determine the phenotypic and genotypic characteristics of Salmonella and pathogenic E. coli present in selected human-animal interfaces in Uganda. 3. To determine the changes in the antimicrobial use by farmers and Veterinarians during COVID19 pandemic.
4. To determine the roles played by different livestock management practices and animal health interventions in escalating AMR in Uganda. 5. To identify and evaluate community based hygienic and disinfection practices that can reduce antibiotic/biocide use. 6. To determine the levels of antimicrobials and biocide residues in slaughtered chicken and cattle cecal samples and abattoir/market wastewater from the selected districts in the country. Secondary objectives: To harness the functions of various policy makers in government institution and build capacity and partnerships for AMR reduction with different organisations within Uganda.
 Uganda 2025-01-10 11:46:51 2028-01-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
Ilemobayo  Fasogbon Victor
ID: UNCST-2023-R008569
 DEVELOPMENT AND EVALUATION OF AN APTAMER-BASED LATERAL FLOW BIOSENSOR FOR RAPID DETECTION OF Mycoplasma bovis P48 PROTEIN
REFNo: HS4931ES

Evaluation of the aptamer-based biosensor using M. bovis infected milk samples,Construction of the aptamer-based biosensor after optimizing the inherent conditions and components,Characterization of the binding affinity and specificity of the aptamer-target interactions,Selection and optimization of the most sensitive aptamer for application in the lateral flow biosensor through molecular interaction studies on previously reported P48 protein aptamers.,he research aim to develop and evaluate an aptamer-based lateral flow biosensor for the rapid and accurate detection of the Mycoplasma bovis P48 protein in infected samples,
 Nigeria 2024-12-23 12:36:24 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Matovu
ID: UNCST-2024-R004929
 The Phylogeny of East African Chlorophytum Ker-Gawl. (Asparagaceae), Phylogeography and Conservation of species found in Uganda
REFNo: NS756ES

1. To establish the phylogeny of Chlorophytum species in the FTEA region and put them in a global context.
2. To unravel the phylogenetic and morphological delimitation of problematic taxa and species complexes within Chlorophytum.
3. To establish the spatial phylogeny of Chlorophytum species that occur in Uganda
4. To establish the conservation status of Chlorophytum species in Uganda

Uganda 2024-12-23 12:34:57 2027-12-23 Natural Sciences Non-Clinical Trial Degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A5409: A Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)
REFNo: HS4036ES

1.2 Primary Objectives

1.2.1 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for each experimental treatment arm to the SOC arm.

1.2.2 To compare new Grade 3 or higher adverse events (AEs) (safety) over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3 Secondary Objectives

1.3.1 To compare time to stable culture conversion by MGIT liquid culture by week 8 for each experimental treatment arm to the SOC arm.

1.3.2 To compare MGIT liquid culture TTP slope over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.3 To compare new Grade 3 or higher AEs (safety) over 26 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.4 To compare discontinuations of anti-TB drugs for any reason prior to 8 and 26 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.5 To determine the dose- and exposure-response relationships between experimental drug estimated pharmacokinetic (PK) parameters with safety and efficacy.

1.3.6 To compare a composite of efficacy and safety outcomes using a risk-benefit approach for each experimental treatment arm to the SOC arm.

1.3.7 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for Arms 3A-3B and Arms 4A-4B compared to Arm 2.

1.3.8 To compare durable cure by 52 weeks after treatment initiation in each experimental treatment arm to the SOC arm.


 Uganda 2024-12-23 12:34:14 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Hakimu Sseviiri
ID: UNCST-2024-R004881
 Formalizing and Elevating Workforce Visibility for Marginalized Sanitation Workers in Kampala, Uganda: Unravelling the intended and Unintended Consequences.
REFNo: SS2816ES

4. To co-design multi-stakeholder pathways towards effective formalization, integration and recognition of sanitation workers. ,3. To analyze the multi-dimensional intended and unintended impacts of formalizing and increasing the visibility of the workforce for the most marginalized workers. ,2. To identify and characterize actors involved in the formalization and visibility raising processes in Kampala city. ,1.To determine the different sanitation workers’ formalization and visibility raising initiatives overtime. ,To unravel the intended and unintended consequences of sanitation workers formalization and visibility enrichment in Kampala city, Uganda. ,
 Uganda 2024-12-23 12:29:36 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
George Alaneme Uwadiegwu
ID: UNCST-2024-R003261
 ARTIFICIAL INTELLIGENCE PREDICTIVE MODELLING OF MECHANICAL AND RHEOLOGICAL PROPERTIES OF GEOPOLYMER-CONCRETE MADE FROM BLENDED BAGASSE AND BANANA-PEEL-ASH
REFNo: SIR365ES

i. To characterize Bagasse ash (BA) and Banana peel ash (BPA) as a geopolymer precursor
ii. To ascertain the optimal combination of the concrete mixture incorporating Bagasse ash (BA) and Banana peel ash (BPA) to replace ordinary Portland cement.
iii. To determine the mechanical and rheological properties of Bagasse ash (BA) and Banana peel ash (BPA) and blended geopolymer concrete matrix.
iv. To develop soft computing predictive models of ANN, GEP and ANFIS to explore the relationships between the Alkalis-activated binder blend and the rheological and mechanical strength response.
v. To compare and validate the models developed in (iv).

 Nigeria 2024-12-23 12:28:18 2027-12-23 Engineering and Technology Non-Clinical Trial Degree Award
Sarah Wambete Namee
ID: UNCST-2024-R003551
 Effectiveness Of A Health Belief Model (HBM)-Based Educational Intervention On Tuberculosis (TB) Treatment Adherence Among Tb Patients In Two Hospitals In Kampala, Uganda: A Randomized Control Trial
REFNo: HS4558ES

To assess the effectiveness of a Health Belief Model (HBM)-based educational intervention on TB treatment Adherence level among TB patients in two hospitals in Kampala, Uganda. 1.To assess the level of TB knowledge among TB patients in two hospitals in Kampala, Uganda. 2.To assess the health beliefs of TB patients towards tuberculosis in two hospitals in Kampala, Uganda 3.To assess the quality of life of TB patients in two hospitals in Kampala, Uganda.
Uganda 2024-12-23 12:26:18 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Piloya Ruth
ID: UNCST-2024-R003592
 Patriarchy and Women Engagement in Environmental Conservation in Northern Uganda: A Case of Gulu District
REFNo: SS2986ES

4. To propose a framework or a model for effective engagement of women in environmental conservation in patriarchal societies.,3. To establish the effectiveness of the strategies used by stakeholders in fostering women’s engagement in environmental conservation within a patriarchal setting in Gulu district.,2. To investigate the extent to which the distinguishing features of patriarchy affect women’s engagement in environmental conservation in Gulu district.,1. To examine in context, the socio-cultural roles performed by women in environmental conservation within the patriarchal structure in Gulu district. ,To examine the extent to which patriarchy affects women\'s engagement in environmental conservation in Gulu district.,
 Uganda 2024-12-23 12:24:42 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
 A Phase 1b, Age De-Escalation/Dose Escalation Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in an African Population of Adults and Children in a Setting of Perennial Malaria Transmission
REFNo: HS5298ES

Primary Objective. To assess the safety and tolerability of MAM01. Secondary Objectives. To assess the safety of MAM01. To characterize the PK of MAM01 following SC, IV, and IM administration of MAM01. To assess the formation of anti-drug antibodies (ADAs) to MAM01. Exploratory Objectives. To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to a placebo. To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to placebo. To assess the protection of MAM01 against events of malaria illness (first/only and all episodes). To correlate MAM01 concentration with Pf infection risk. To assess the complexity of Pf infection following administration of MAM01 or placebo.
Uganda 2024-12-23 12:23:27 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Outcome Evaluation of the Young People and Adolescent Peer Support (YAPS) program Implementation in Uganda
REFNo: HS4809ES

1. To assess fidelity of the YAPS program implementation by different stakeholders (MoH, Implementing Partners, Districts, Facilities, and YAPS personnel)
2. To establish the effect of the YAPS program on the clinical cascade for Adolescents and Young People Living with HIV.
3. To explore perspectives of YAPS and other stakeholders on the effectiveness of the YAPS program.
4. To estimate the incremental costs of implementing the YAPS model at the different levels of implementation (National, District and health facility)

 Uganda 2024-12-23 12:17:40 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DANLADI MAKERI
ID: UNCST-2024-R005300
 Characterization of Staphylococcus aureus Isolated from Foot Ulcers of Diabetic Patients Attending Kampala International University Teaching Hospital, Bushenyi District, Uganda
REFNo: HS4836ES

v. To determine the molecular phylogeny of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iv. To determine the antibiogram profile of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iii. To assess the phenotypic distribution of Staphylococcus aureus in foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda.,ii. To determine factors associated with diabetic foot infections among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,i. To determine the prevalence of diabetic foot infection among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda,To characterize Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,
 Nigeria 2024-12-23 12:15:59 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Omujal
ID: UNCST-2019-R000428
 DOCUMENTATION OF BATWA INDIGENOUS PEOPLE AND LOCAL COMMUNITIES’ KNOWLEDGE FOR BIO-PROSPECTING FOR THERAPEUTICS PRODUCTS
REFNo: NS658ES

c) To identify priority natural medicinal resources that can be used by BIP for development of therapeutic products for specific diseases ,b) To assess the availability status of medicinal resources used for TMK by the BIP,a) To document the traditional medicine practices of the BIP,To document TMK of the Batwa indigenous people for the development of therapeutic products.,
 Uganda 2024-12-23 12:14:59 2027-12-23 Natural Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Epidemiology of pediatric severe malaria in the Kasese District of western Uganda
REFNo: HS5367ES

Study Objectives The overarching goal of this proposed project is to describe the epidemiology of severe malaria among children in the Kasese District of western Uganda. Our scientific objective is to determine if the demographic, clinical, and laboratory characteristics of children admitted to a more urban level IV health center are different from our previous findings at a rural level III health center. To test this hypothesis, we propose to: AIM 1: Describe the demographic characteristics of children admitted to SPHC with a diagnosis of malaria. We will conduct a prospective, observational study, enrolling children admitted to the IPD. Participating caregivers will complete a questionnaire documenting basic demographic factors as well as information about the household (e.g., location, LLIN access and use). We hypothesize that most children will be (i) <12 years of age, (ii) from areas within 20km of SPHC, and (iii) have previously sought care at lower-level facilities. AIM 2: Document the clinical and laboratory characteristics of children admitted to SPHC with a diagnosis of malaria: We will elicit a history of illness from the caregiver and record relevant information including vital signs, results of laboratory testing (e.g., malaria RDT, hemoglobin, etc.), along with treatments administered during the hospitalization. We hypothesize that nearly all children will receive ≥24 hours of intravenous artesunate, but there may be substantial variation in dosing. AIM 3: Estimate measures of severe malaria incidence and associated morbidity and mortality among children presenting to SPHC with malaria. We will record the results of laboratory testing for malaria in the OPD to determine the malaria positivity rate and incidence of SM (i.e., proportion with a positive RDT who are admitted). Among those who are admitted, we will document disposition (e.g., discharge, transfer, death) and complete follow up at 14, 30, 45, and 60 days post-discharge. We hypothesize that mortality will be greatest among children referred from lower-level facilities and those with delayed presentations
Uganda 2024-12-23 12:12:56 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justus Asasira
ID: UNCST-2021-R012092
 Socioeconomic and Environmental Impacts of Biomass Briquettes and Solar Cooking Technologies Acceptance by Households in Southwestern Uganda
REFNo: SS2319ES

1. To explore the stakeholders’ perceptions about adopting biomass briquettes for cooking in Southwestern Uganda.
2. To assess the influence of business models on the acceptance and economic feasibility of biomass briquettes and solar technologies for cooking in Southwestern Uganda.
3. To compare the environmental impacts and benefits of producing and using solar technologies with non-renewable sources of energy for cooking in Southwestern Uganda.
4. To identify the design attributes that make biomass briquettes and solar cooking technologies socially acceptable by households in Southwestern Uganda.

 Uganda 2024-12-23 12:11:58 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
OSCAR AYUYA INGASIA
ID: UNCST-2024-R002553
 Gender Analysis; Address gendered aspects of awareness of lower-risk plant protection products/technologies in Uganda
REFNo: A534ES

To explore the roles men and women play in pest management and the products used for pest management in potato farming,To assess the differences between men, women, and young people\'s, values, power dynamics and behaviors which shape their access to and use of digital tools.,To examine the traditional pest prevention technologies, and the gendered obstacles faced by men women and young people,To respond to the needs of farmers and the systems that support them, by helping countries predict, prevent, and prepare for plant health threats, thereby reducing crop losses. ,
 Kenya 2024-12-23 12:09:26 2027-12-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
Isaac Kitone
ID: UNCST-2024-R002847
 Kabale University (KAB) Sustainable Energy Generation System (KSEG) Project
REFNo: SIR421ES

To test the automated non-fossil fuel driven power generator,To construct an automated non-fossil fuel driven power generator ,To design an automated non-fossil fuel driven power generator ,To collect data on existing generator power needs in three western Ugandan districts, Kabale, Mbarara and Ntungamo,To design and construct an automated non-fossil fuel driven power generator ,
 Uganda 2024-12-23 12:07:01 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 UNMET ORAL HEALTH NEEDS AND BARRIERS TO ORAL HEALTH AND SEXUAL HEALTH SERVICE UTILISATION AMONG MEN WHO HAVE SEX WITH MEN AND TRANSGENDER PEOPLE IN UGANDA: A MIXED METHODS PILOT STUDY
REFNo: HS5226ES

Objective 1: Estimate the prevalence of oral diseases, HIV, OHPV,
and self-reported STIs and their impact on oral health conditions in
MSM/TGP.
Objective 2: Identify the key barriers to health service utilization
experienced by MSM/TGP.
 Uganda 2024-12-23 12:05:34 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOYCE NAMWASE
ID: UNCST-2024-R005002
 FEASIBILITY AND EFFECTIVENESS OF A TRAINING INTERVENTION FOR INFORMAL CAREGIVERS OF PEOPLE LIVING WITH DEMENTIA IN RURAL UGANDA (FETIC-DU)
REFNo: HS5165ES

3. To evaluate the feasibility and effectiveness of the training program in improving knowledge and skills of informal care givers for persons with dementia in rural Uganda. 1.4 Research questions
Uganda 2024-12-23 12:04:08 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Murokora Murokora
ID: UNCST-2024-R002689
 Outcomes Evaluation of Reproductive, Maternal and Newborn Care Interventions Implemented by BAMA in Uganda
REFNo: HS5155ES

General Objective
To evaluate the outcomes of Reproductive, Maternal and Newborn Care interventions at BAMA Supported Sites in Uganda.

Specific Objectives
1. To evaluate the impact of NMH interventions on IMMR and IPMR since 2015
2. To explore factors influencing mortality trends since 2015
3. To document the optimum package of MNH interventions that impacted MMR and PMR
4. To assess the impact of BAMA interventions on HPV vaccination uptake for out-of-school girls as well general population (women aged 25-49) cervical cancer screening and linkage to appropriate services
5. To assess the effect of BAMA project interventions on infant development outcomes and adolescent mother’s physical, social, and mental wellbeing outcomes
6. To determine the feasibility and sustainability of MRP
7. To assess the impact of the implementation of MPS transport solution on MNH outcomes
8. To assess the design and impact of the mentor midwives model on MNH outcomes
9. To determine optimum mentorship package and its impact on quality of care and clinical outcomes

 Uganda 2024-12-23 12:03:10 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
 Faecal exposure behaviours, risk profiles, and predicted efficacy of Water Sanitation and Hygiene interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings
REFNo: HS5190ES

4. To predict the efficacy of suggested interventions on reducing faecal exposure in the private domain in Imvepi and Cox’s Bazar refugee settings (Study IV),3. To determine the factors associated with faecal exposure among children and adults in Imvepi and Cox’s Bazar refugee settings (Study III),2. To determine the faecal exposure risk profile of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study II),1. To explore faecal exposure behaviours and pathways of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study I),To establish the faecal exposure profiles and associated factors in the private and public domain and predict the efficacy of suggested interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings so as to guide exposure reduction interventions.,
 Uganda 2024-12-23 12:01:21 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
DANIEL BUGEMBE LULE
ID: UNCST-2024-R015332
 DEVELOPMENT OF NOVEL APPROACHES FOR HIV DRUG RESISTANCE DETECTION USING NANOPORE SEQUENCING TECHNOLOGY
REFNo: HS5352ES

Objectives and Hypothesis
Primary Objective
To develop an end-to-end nanopore NGS workflow for the routine clinical detection of HIV drug
resistance (HIVDR).
Secondary Objective
To compare the HIVDR scoring between Sanger and Nanopore sequencing method of matched samples
to evaluate their concordance for detecting drug resistance mutations.
Exploratory Objectives
1. To develop a method for PCR amplification of low plasma viral load samples, genotype these
with the nanopore method and derive HIVDR mutations.
2. To identify improvements to the nanopore base-calling algorithms that may obviate high error
rates.
3. Provide an expeditious end-to-end analysis pipeline for analysis of HIVDR of Nanopore generated
sequences.
4. To establish if the various base-calling errors of the Nanopore sequencing are occurring in a
stochastic or non-stochastic manner.
 Uganda 2024-12-23 11:59:00 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Identifying Barriers to Infection Prevention & Control Guideline Adherence in Western Uganda.
REFNo: HS5360ES

Primary Objectives The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in IPC knowledge amongst HCP and how they may relate to IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts. Specific Aims AIM 1: Evaluate adherence to national IPC guidelines across a variety of healthcare facility levels in Western Uganda via a standardized observation protocol through facility-level evaluations. 1A. Guided by Uganda’s national IPC best practices for healthcare facilities and a standardized facility-level checklist adopted from the World Health Organization, we will perform observations of the facility’s physical characteristics, healthcare supplies, and healthcare personnel workflow, including observations of hand hygiene adherence with a standardized checklist. AIM 2: Assess IPC knowledge, attitudes, and practices of healthcare personnel at multiple levels of Uganda’s national healthcare system, identifying primary barriers to National IPC Guideline adherence. 2A. Healthcare Personnel Surveys: Surveys will consist of both qualitative and quantitative elements to ascertain information on their awareness of foundational IPC concepts within national guidelines, circumscribe a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes that may prevent rigorous adherence to IPC guidelines. 2B. Healthcare Personnel Focus Group Discussions: Focus group discussions will be oriented in such a manner as to ascertain common themes and information on awareness of foundational IPC concepts, gain a perspective on the experience of IPC practices across a variety of facility levels and HCP roles, and understand what limitations are experienced by HCP during their daily patient care-oriented activities. Through these discussions, we hope to gain a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes, gaps in IPC education and/or training, and HCP workflow concerns that may prevent rigorous adherence to IPC guidelines.
Uganda 2024-12-23 11:57:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Stakeholder perspectives for the approach to treatment recommendations for kids presenting with advanced or incurable cancer
REFNo: HS5203ES

Using the instrument described in 1.1, identify personal, professional, and contextual factors influencing the perspectives and decision-making approaches of key non-physician stakeholders in Uganda in the upfront care of children diagnosed with advanced or incurable cancer through qualitative data collection and analysis.,To adapt an existing instrument for use in Uganda that helps explore the personal, professional, and contextual factors that influence the perspectives and decision-making approaches of key non-physician stakeholders (patients, families, multidisciplinary clinicians), specifically with respect to recommending upfront curative treatment versus non curative treatment (for example, with palliative-intent) in children diagnosed with advanced or incurable cancer in LMICs.,
 Uganda 2024-12-23 11:55:35 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Duula Waiswa
ID: UNCST-2024-R015879
 BURDEN AND SPATIAL DYNAMICS OF TICK SPECIES AMONG CATTLE GRAZING ALONG THE BUFFER ZONE OF LAKE NAKUWA IN KALIRO DISTRICT
REFNo: A529ES

1. Determine the burden of tick species infesting cattle grazing along the buffer zone of Lake Nakuwa.
2. Determine spatial dynamics of the different tick species infesting cattle grazing along the buffer zone of Lake Nakuwa
3. Identify factors promoting and maintaining high tick infestation burdens along the buffer zone of Lake Nakuwa.

Uganda 2024-12-23 11:54:12 2027-12-23 Agricultural Sciences Non-Clinical Trial Degree Award
Edith Namakula
ID: UNCST-2022-R006923
 Pethidine versus Morphine use for management of postoperative pain in Mulago National Referral Hospital, Uganda
REFNo: HS5240ES

1. To determine the prevalence of pethidine versus morphine prescription for the management of postoperative pain in MNRH, Uganda.
2. To explore the side effects experienced during the use of pethidine versus morphine for the management of postoperative pain in MNRH, Uganda.
3. To determine the factors associated with pethidine prescription for the management of postoperative pain in MNRH, Uganda.
4. To explore barriers and facilitators of pethidine versus morphine prescription in the management of postoperative pain in MNRH, Uganda.

 Uganda 2024-12-23 11:53:21 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Birungi
ID: UNCST-2024-R015642
 Receiving cash amidst competing norms: the case of breastfeeding South Sudanese refugees in bidi-bidi settlement, uganda.
REFNo: SS3525ES

To explore how breastfeeding South Sudanese refugees navigate their cultural norms and cope with cash transfer project norms.

Specific objectives.
1. To establish the cultural norms that guide breastfeeding among South Sudanese refugees in bidi-bidi settlement.
2. To examine how beneficiaries relate with the official norms (project and state norms) in bidi-bidi settlement.
3.To assess the impact of cultural norms on the participation of south sudenese refugees in cash transfer interventions in bidi-bidi settlement.
Uganda 2024-12-23 11:52:27 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
JAMMY OMARA
ID: UNCST-2022-R009800
 ASSESSING DIFFERENTIAL DIAGNOSES, ASSOCIATED FACTORS AND GEOSPATIAL DISTRIBUTION OF CHRONIC LOWER LIMB ULCERS AMONG ADULTS IN ZOMBO DISTRICT, UGANDA
REFNo: HS5272ES

General objective
To determine differential diagnoses and associated factors for chronic lower limb ulcers among adults in Zombo district.

specific objectives
1. To determine the differential diagnoses for chronic lower limb ulcers among adults in Zombo district
2. To describe the associated factors with chronic lower limb ulcers among adults in Zombo district
3. To describe the geospatial distribution of individuals with chronic lower limb ulcers in Zombo district
 Uganda 2024-12-23 11:51:16 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Filippo Ferraro
ID: UNCST-2024-R016002
 Key Performance Indicator Framework for refugees integration in Uganda
REFNo: SS3441ES

The main objectives of the study are to:
1. ldentify the specifics support needs of refugees in Uganda.
2. Explore the perception and understanding of refugee’s local people and stakeholders
on the concept of integration.
3. Explore the existing welfare and integration programme available in Uganda.
4. Determine the facilitators and the barriers to the integration of refugees in Uganda.
5. Develop a Key Performance Indicator framework for the integration of refugees in
Uganda.

 Italy 2024-12-23 11:50:16 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Chinatsu  Hattori
ID: UNCST-2024-R002354
 Determinants of Family Planning use among women of reproductive age in refugees and host communities in Lamwo District, Uganda: a cross-sectional study
REFNo: HS5291ES

Main Objective To identify the factors influencing the utilization of family planning methods among women of reproductive age in the refugee settlement and host communities in Lamwo District, Uganda. Specific Objectives (i)To estimate the contraceptive prevalence among women of reproductive age in both refugee settlements and host communities. (ii)To analyze contraceptive use in terms of readiness, willingness, abilities, and other associated factors among women of reproductive age in refugee settlements and host communities.
 Japan 2024-12-23 11:49:09 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 OUTCOMES AND HEALTHCARE NEEDS OF PATIENTS WITH HIV AND KIDNEY DISEASE IN UGANDA.
REFNo: HS5305ES

1. To determine the contribution of CKD to 5-year mortality among PWH in Uganda.
2. To determine barriers and facilitators to nephrology care among PWH and CKD comorbidity in Uganda.

 Uganda 2024-12-23 11:46:08 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAKAYISO  ESEZA
ID: UNCST-2024-R002957
 INFLUENCE OF SAVINGS AND CREDIT COOPERATIVE STRATEGIES ON FINANCIAL EMPOWERMENT OF WOMEN IN MASAKA DISTRICT, UGANDA.
REFNo: SS3454ES

The study aims to: i. Evaluate the impact of financial training and advisory services on women\'s financial literacy and decision-making in Masaka District. ii. Investigate the effectiveness of loan and credit strategies in promoting women\'s financial empowerment. iii. Assess the role of savings strategies in fostering women\'s financial empowerment. iv. Evaluate the influence of government policies on women\'s access to financial services and economic opportunities. v. Examine how cultural factors moderate the relationship between SACCO strategies and women\'s financial empowerment.
 Uganda 2024-12-23 11:44:21 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Tukwasibwe
ID: UNCST-2022-R011535
 Surveillance of malaria drug and diagnostic resistance in newly arrived refugees in Uganda
REFNo: HS5317ES

1. To characterize drug resistance profiles of P. falciparum parasites collected from newly arrived refugees in Uganda
2. To evaluate the prevalence of P. falciparum HRP-2 gene deletions that mediate diagnostic resistance in newly arrived refugees in Uganda

 Uganda 2024-12-23 11:42:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 An Evaluation of Perceptions and Effectiveness of the Ethical Review Process at Makerere University: A pilot Evaluation at the School of Health Sciences Research and Ethics Committee
REFNo: HS5322ES

1. Assess the perceptions of researchers (from the departments of pharmacy, nursing, dentistry, staff at Makerere University and researchers outside the institution) regarding MaKSHSREC’s ethical review process.
2. To assess the level of satisfaction among researchers on the existing MaKSHSREC ethical review processes.
3. Assess the efficiency and effectiveness of MaKSHSREC ethical review processes.
4. Explore the challenges and areas for improvement in the current MaKSHSREC ethical review processes.

Uganda 2024-12-23 11:38:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PAULA KWOREKWA
ID: UNCST-2024-R005035
 Assessing the Impact of COVID-19 on the Knowledge, Attitude, and Practice of Medical Waste Management among Waste Handlers at Luweero General Hospital
REFNo: HS5350ES

Main Objective:
To investigate the impact of COVID-19 on the Knowledge, attitude, and practice of medical waste management among waste handlers at Luweero General Hospital.
Specific Objectives:
1. To determine the knowledge of medical waste handlers in recommended waste management practices following the COVID-19 pandemic.
2. To investigate the attitude of medical waste handlers towards practicing the recommendations for proper Medical Waste Management in the post COVID-19 pandemic era.
3. To compare the practices for medical waste management before and after the COVID-19 pandemic.


Uganda 2024-12-23 11:37:27 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Aziku
ID: UNCST-2023-R007595
 Baseline Study for Safe and Inclusive Cities Project -Uganda.
REFNo: SS3476ES

To evaluate the achievement of the programme’s intended outcomes, integrating qualitative insights and quantitative data on change in outcome indicators over time (from endline to end-line).

Identify and validate good practices, learnings, and examples of innovation on gender transformative programming.

To generate practical recommendations related to the programme outcomes and the approaches to inform future programming.
 Uganda 2024-12-23 11:36:17 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Nansubuga Kaaya
ID: UNCST-2024-R002104
 Piloting a frugally innovated surgical fracture table in Uganda: Assessing its functionality, usability, and acceptability.
REFNo: SIR454ES

To pilot a frugally innovated surgical fracture table in Uganda and assess its functionality, usability, and acceptability in resource-limited healthcare settings through:
1. To evaluate the functionality of the frugally innovated surgical fracture table selected healthcare professionals by assessing its ability to: securely position patients, allow for stable positioning and smooth adjustment of the tentative limb position.
2. To assess the usability of the surgical fracture table selected healthcare professionals by measuring: the time required for set-up, the perceived ease of use of the table, the perceived comfort levels during manipulation.
3. To determine the acceptability of the surgical fracture table among selected healthcare professionals by assessing: their overall satisfaction with the table's design, functionality, and usability, willingness to recommend or use the table in their clinical practice and their perceptions of the table's potential impact on patient outcomes and safety

 Uganda 2024-12-23 11:35:30 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
 A phase III, Multicenter, Randomized, Placebo Controlled, Double blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises
REFNo: HS5365ES

To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of VOCs* that are healthcare professional (HCP)-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in 12 months prior to the screening visit).
To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of all VOCs including VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) and VOCs that are self-managed without recommendations from HCP during the event over the planned 52 week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in the 12 months prior to the Screeening visit
To evaluate the annualized rate of VOCs by type of management between treatment arms over the planned 52-week treatment period: • VOCs that are HCP-managed at a health care facility • VOCs that are HCP-managed via remote consultation • VOCs that are self-managed without recommendations from HCP during the event • VOCs that are HCP-managed via remote consultation or self-managed without recommendations from HCP during the event
To evaluate the time to first VOC that is HCP managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
To evaluate the proportion of participants free from VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
 Uganda 2024-12-23 11:34:49 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Wakib Bunnya
ID: UNCST-2024-R016233
 An analysis of youth participation in elections
REFNo: SS3488ES

Three key objectives guide the research: first, to examine the role of voter education in shaping youth participation; second, to analyze the inclusion of young women and youth with disabilities in elections; and third, to explore the role of youth in peacebuilding and election-related violence.
Uganda 2024-12-23 11:32:13 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Spencer  Birungi
ID: UNCST-2024-R003017
 TRANSBOUNDARY MIGRATION SURVEILLANCE CONTROLS AND THE INFECTIOUS DISEASES MONITORING MECHANISMS: THE CASE OF WEST NILE UGANDA-DEMOCRATIC REPUBLIC OF THE CONGO
REFNo: SS3504ES

1. To describe the transboundary migration patterns along the West Nile Uganda – DRC borderline
2. To explore the transboundary migration infectious disease monitoring in practice along the West Nile Uganda –DRC borderline
3. To establish the association between the transboundary migration surveillance controls and the practices in monitoring of infectious diseases at border points; of entry
4. To describe the adherence to protocols for infectious disease monitoring before, during and after the outbreaks at border points of entry


 Uganda 2024-12-23 11:29:01 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
MARGARET NAKATO
ID: UNCST-2024-R002167
 LIBRARY SERVICE QUALITY AND USER SATISFACTION AMONG GRADUATE STUDENTS IN THE FACULTIES OF SCIENCE AND ENGINEERING AT KYAMBOGO UNIVERSITY, UGANDA
REFNo: SS3545ES

The objectives of the study are to:
1. Establish the effect of tangibility on graduate students' satisfaction with library services at Kyambogo University.
2. Determine the effect of reliability on graduate students' satisfaction with library services at Kyambogo University.
3. Examine the effect of empathy on graduate students' user satisfaction with library services at Kyambogo University.
4. Establish the effect of responsiveness on graduate students' user satisfaction with library services at Kyambogo University.
5. Determine the effect of assurance on graduate students' user satisfaction with library services at Kyambogo University.
6. Develop a framework for measuring library service quality at Kyambogo university
 Uganda 2024-12-23 11:27:18 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Lily Bastian R
ID: UNCST-2024-R002139
 A Mixed Methods Study on Psychosocial and Health Practices Among Young People Living with HIV (YPLHIV) in Kampala, Uganda
REFNo: HS5354ES

The objective of this study is to assess the impact of resilience on sexual practices, behaviors, and health-related outcomes among young people living with HIV (YPLHIV) in Kampala, Uganda.
 USA 2024-12-23 11:24:59 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Andrew Seguya Ggunga
ID: UNCST-2024-R002054
 Assessing the World Economic Forum’s Travel and Tourism Development Index as A Framework for Uganda's Tourism Growth
REFNo: SS3501ES

To create a prioritised ranking of factors that accurately predict tourism and travel growth in Uganda, using data-driven methods and expert analysis to measure the impact of each factor on key growth indicators such as tourist arrivals, revenue, and employment.,To investigate, over the same period, whether there are factors not included in the WEF Travel and Tourism Development Index framework that effectively predict T&T growth in Uganda.,This study will investigate, using data from the Tourism Master Plan 2014-2024, whether the factors included in the WEF Travel and Tourism Development Index framework (such as infrastructure, environmental sustainability, and government policies) effectively predict T&T growth in Uganda, measured through indicators of tourist arrivals, revenue, and employment.,
 Uganda 2024-12-23 11:23:37 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
John Francis Mafuko Francis
ID: UNCST-2024-R002186
 Management of medicinal indigenous knowledge on snakebites in selected districts of Eastern Uganda.
REFNo: SS3517ES

i.To examine the sharing of the medicinal indigenous knowledge by the snakebites herbalists’ in Pallisa and Kamuli districts of Eastern Uganda.
ii. To establish the essential kind of information to be documented by the medicinal indigenous herbalists on snakebites management in Pallisa and Kamuli districts of Eastern Uganda for future use.
iii. To establish whether there is incorporation of the explicit medicinal indigenous herbalists’ knowledge on snakebites by the medical practitioners in Pallisa and Kamuli districts of Eastern Uganda.
iv. To evaluate the likelihood of the community in using the two-eyed seeing framework to integrate western knowledge and indigenous knowledge to deal with the snakebites in Pallisa and Kamuli districts of Eastern Uganda.
v. To propose a medicinal indigenous snakebites herbalists’ knowledge management framework in Pallisa and Kamuli districts of Eastern Uganda.

Uganda 2024-12-23 11:21:49 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Ernest Mwebaze
ID: UNCST-2024-R015880
 EmpowerHerAI: Advancing Gender Equality and Responsible AI in Sub-Saharan Africa through Gender and Responsible AI Network (GRAIN)
REFNo: SIR456ES

General Objective
The general objective of the research study is to develop and evaluate low-resource multilingual AI language models by addressing issues of gender fairness, bias, and trustworthiness, and promoting inclusive and culturally contextualized AI tools for African languages.

Specific Objectives
1. Conduct a comprehensive review of existing datasets and training processes to identify potential gender gaps in relation to fairness, bias, and trustworthiness issues in low-resource multilingual language models.
2. Curate and collect parallel datasets for selected African languages to improve the development of low-resource multilingual language technologies.
3. Develop a robust and generalizable framework for creating AI language tools that address gender fairness, safety, and trustworthiness in non-English, low-resource multilingual models.
4. Develop a framework for incorporating human feedback and preferences into evaluating multilingual machine translation, speech recognition, and synthesis models, addressing the unique gender challenges presented by low-resource settings.

 Uganda 2024-12-23 11:15:21 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
KADAI LAWAN ALHAJI
ID: UNCST-2024-R015583
 Analysis of Antimicrobial Metabolites of Aspergillus fumigatus, Isolated from Kitagata Hot Spring Utilizing Metabolomic and Molecular Docking Techniques
REFNo: NS891ES

Objectives
1 To ascertain physicochemical characteristics of Kitagata hot springs.
2 To isolate and identify thermophilic Aspergillus fumigatus from water sample of Kitagata hot spring.
3 To produce, extract and fractionate metabolites of thermophilic Aspergillus fumigatus to be isolated.
4 To determine the efficacy of antimicrobial value of extracted metabolites from the study organisms.
5 To simulate and predict the interaction between two structures of the metabolites

 Nigeria 2024-12-23 11:14:18 2027-12-23 Natural Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Improving business continuity for health services following extreme weather events (RESilience in HeAlth Post-Extreme weather events-RESHAPE Study)
REFNo: HS5370ES

Overall Objective

The primary objective of the proposed study is to develop and deploy the tools that will help healthcare services to better prepare for EWEs, cope better when affected by such events, and recover more effectively afterwards.


Specific Aims
Aim 1: Describe the healthcare systems in the Kasese District, and its served communities and how both have been affected by and responded to EWEs to provide a foundation for locally relevant insights into processes and adaptations, and their influence on health outcomes

Aim 2: Develop, with local partners, through business continuity planning, resilience engineering and participatory research methods, protocols for EWE preparedness, response and recovery, and guidance on good practices, knowledge exchange, and interventions development as a process for enhancing resilient healthcare delivery

Uganda 2024-12-23 11:10:15 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bamidele Olaiya Charles
ID: UNCST-2024-R003262
 OPTIMIZATION OF MECHANICAL AND THERMAL PROPERTIES OF SANDCRETE-BRICKS INCORPORATING SAWDUST AND BANANA-LEAF ASH USING GENETIC ALGORITHM AND ARTIFICIAL-NEURAL-NETWORK
REFNo: SIR366ES

i. To characterize the Sawdust Ash (SDA) and Banana Leaf Ash (BLA)
ii. To examine the effects of varying percentages of sawdust and banana-leaf ashes on the mechanical (compressive strength, flexural strength) and thermal properties of sandcrete bricks.
iii. To develop an optimization approach using a combination of Genetic Algorithm (GA) and Artificial Neural Network (ANN) to determine the optimal mix proportions for sandcrete bricks with improved mechanical and thermal properties.
iv. To evaluate the mineralogical and microstructural properties of the sandcrete bricks made with the SDA and BLA.
v. To provide insights into the sustainable and energy-efficient production of sandcrete bricks incorporating sawdust and banana-leaf ash

 Nigeria 2024-12-23 11:08:48 2027-12-23 Engineering and Technology Non-Clinical Trial Degree Award
Gertrude Nakigozi
ID: UNCST-2023-R007979
 CLIMATE SHOCK PILOT STUDY
REFNo: NS890ES

Validate the climate shock survey for Lake Victoria basin/ South western Uganda and examine determinants of climate variability impact, and conduct a comparison on the effects of Climate variability by community and occupation Climate variability
 Uganda 2024-12-23 11:07:21 2027-12-23 Natural Sciences Non-Clinical Trial Non-degree Award
Julia Harrison
ID: UNCST-2024-R004345
 Neonatal and Pediatric HIV and Sepsis on a Pediatric Surgery Ward in Uganda: A Prospective Study Standardizing HIV Testing and Sepsis Resuscitation and Treatment Algorithm to Guide Clinical Care
REFNo: HS5416ES

Main Objective 1. The general objective of this project is to determine the prevalence of sepsis, the underlying etiologies leading to sepsis, and the prevalence of HIV among patients with sepsis on the pediatric surgery ward at Mulago hospital. Additionally, our objective is to implement the 2020 surviving sepsis campaign guidelines on the pediatric surgery ward at Mulago Hospital. Specific Objectives 1. We will identify the etiologies leading to sepsis on the pediatric surgery ward at Mulago Hospital by examining the underlying pathologies in patients diagnosed with sepsis over a period of 7 months 2. We will determine the prevalence of HIV among patients with sepsis on the pediatric surgery ward at Mulago Hospital by testing patients with sepsis for HIV over a period of 7 months 3. We will implement the 2020 Surviving Sepsis Campaign Guidelines on the pediatric surgery ward at Mulago Hospital over a period of 1 month 4. We will determine the prevalence of sepsis on the pediatric surgery ward at Mulago Hospital by tracking patients diagnosed with sepsis over a period of 7 months
 USA 2024-12-23 11:05:56 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SIYA AGGREY
ID: UNCST-2019-R001737
 WATER HYACINTH’S EXTENT ON FRESHWATER SITES WITHIN QUEEN ELIZABETH NATIONAL PARK, UGANDA; IMPLICATIONS ON WATER QUALITY AND WILDLIFE HEALTH
REFNo: NS894ES

i) To assess the spatial extent and distribution of Water hyacinth (Pontederia crassipes) in Lake Edward, Lake George and the Kazinga Channel
ii) To examine the determinants of Water hyacinth (Pontederia crassipes) distribution within Lake Edward, Lake George and the Kazinga Channel
iii) To assess impact of Water hyacinth (Pontederia crassipes) on water quality within Lake Edward, Lake George and the Kazinga Channel
iv) To analyze policies that would support management of Water hyacinth (Pontederia crassipes) invasion within Lake Edward, Lake George and the Kazinga Channel.

 Uganda 2024-12-23 11:03:12 2027-12-23 Natural Sciences Non-Clinical Trial Non-degree Award
Solomon Kibudde
ID: UNCST-2021-R013747
 PHASE II RANDOMIZED NON-INFERIORITY TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOR LOCALLY ADVANCED CERVICAL CANCER IN UGANDA.
REFNo: HS5348ES

1) To compare the incidence of grade 3+ gastrointestinal and genitourinary toxicity at 1 year post-treatment with hypofractionated radiotherapy (40 Gy in 16 fractions) and conventional fractionated radiotherapy (45 Gy in 25 fractions) in women with cervical cancer in Uganda.
2) To evaluate and compare local control and cervical cancer-specific survival rates at 1 year after hypofractionated radiotherapy (40 Gy in 16 fractions) versus conventional radiotherapy (45 Gy in 25 fractions).
3) To determine the association between stage-adjusted mean squamous cell carcinoma antigen (SCC-Ag) at 1-month post-treatment with the Progression-free survival at 1- year post-treatment with hypofractionated radiotherapy (40 Gy in 16 fractions) or conventionally fractionated radiotherapy (45 Gy in 25 fractions).
4) To compare the costs of healthcare to patients with cervical cancer treated with hypofractionated radiotherapy (40 Gy in 16 fractions) versus conventional fractionated radiotherapy (45 Gy in 25 fractions).
5) To evaluate patient-reported outcomes and quality of life in patients with cervical cancer treated with hypofractionated radiotherapy (40 Gy in 16 fractions) versus conventional fractionated radiotherapy (45 Gy in 25 fractions).

 Uganda 2024-12-23 11:01:22 2027-12-23 Medical and Health Sciences Clinical Trial Degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Investigation of mpox transmission, disease sequel, and molecular epidemiology in Uganda (Mpoxep)
REFNo: HS5387ES

Primary Objectives
1. To characterize the socio-demographic, clinical, immunological, and virologic epidemiology of Mpox cases in Uganda.
2. To describe the natural history and asymptomatic transmission dynamics of Mpox among contacts.
3. To assess risk factors for clinical hospitalization, ICU admission, and fatal Mpox outcomes.
4. To investigate long-term sequelae among Mpox survivors.

Secondary Objectives
1. To determine the incidence and prevalence of Mpox among high-risk populations (long-distance truck drivers, commercial sex workers, refugees, and PLHA).
2. To assess infection risk and asymptomatic transmission using serology among contacts.
3. To identify risk factors for infection among ‘de novo’ cases with no documented epidemiological link.
4. To explore socio-anthropological factors influencing Mpox transmission, prevention, and care-seeking behavior.
5. To identify potential animal reservoirs of MPXV in Uganda.
6. To describe histopathologic features of Mpox skin lesions and localization of MPXV in different body organs and tissues.

 Uganda 2024-12-23 10:56:56 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wycliff Odude
ID: UNCST-2024-R002431
 Small-scale field evaluation of the efficacy, residual activity and acceptability of Sovrenta® 15WP against Malaria Vectors in Adjumani district, West Nile, Uganda.
REFNo: HS5300ES

1. To determine the susceptibility levels of both wild-type and Kisumu strain malaria vectors to Sovrenta® 15WP insecticide in Adjumani District, West Nile, Uganda.
2. To determine the comparative residual activity of Sovrenta® 15WP and Actellic 300CS insecticides on common wall-type surfaces in Adjumani, West Nile, Uganda over 10 months.
3. To generate specific information related to the acceptability of Sovrenta® 15WP insecticide as a new product by the community in Adjumani, West Nile, Uganda.
4. To assess the ease of use of the Sovrenta by the spray operators under field conditions in Adjumani District, West Nile, Uganda.

Uganda 2024-12-10 16:05:33 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Roy Mayega William
ID: UNCST-2022-R010983
 Africa Regional Education System Resilience Observatory (ARESRO) Study - A Case Study of Uganda
REFNo: SS3453ES

General objective
To contribute to the improvement of the education system resilience in Uganda through evidence-informed programming.
Specific objectives
1) To explore the meanings and practices of education system resilience in Uganda
2) To explore the potential impact of future shocks and stressors, risk, vulnerability, and capacities (absorptive, adaptive, and transformative) on the future education ecosystems and outcomes in Uganda
3) To identify effective approaches and planning to address the future shocks and stressors, risks, vulnerabilities, and capacity for better education system resilience in Uganda

 Uganda 2024-12-10 16:04:12 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
ALEX ARIO RIOLEXUS
ID: UNCST-2024-R002455
 DEATHS AND INFECTIONS AVERTED, A COST - EFFECTIVENESS ANALYSIS AND FACTORS THAT INFLUENCE ADOPTION AND IMPLEMENTATION OF THE 7-1-7 TARGETS IN UGANDA: A case study of three Priority diseases
REFNo: HS5278ES

1.To estimate the number of deaths and cases from prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) averted if 7-1-7 targets are met in Uganda
2.To conduct a cost-effectiveness analysis for Uganda’s Ministry of Health implementing the 7-1-7 framework in responding to prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) using societal perspective.
3.To explore and profile the factors that influence the adoption and implementation of 7-1-7 targets among different stakeholders in Uganda
 Uganda 2024-12-10 16:02:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Nkwanzi
ID: UNCST-2024-R002493
 Examining the Impact of Adverse Childhood Experiences on Human Trafficking Vulnerability and the Long-term Mental Health Outcomes of Women Survivors of Trafficking (18-35 years) in Uganda.
REFNo: SS3451ES

Aim 1: To quantitatively examine the association between ACEs, human trafficking vulnerability, and long-term mental health outcomes (anxiety, depression, PTSD). Aim 2: To determine the factors that moderate the effects of ACEs on human trafficking vulnerability and the long-term mental health outcomes of women survivors of trafficking. Aim 3: To qualitatively explore sources of resilience and gaps in existing policies and services for women affected by human trafficking in Uganda To inform comprehensive survivor centered interventions, this study will collect additional data on quality of life, gender-based violence, substance use and financial capability of survivors of trafficking.
Uganda 2024-12-10 16:01:57 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Akusa Patrice Mawa
ID: UNCST-2024-R015660
 Service availability and readiness assessment for establishing biobanks of patient left-over samples from routine healthcare provision in Uganda and Kenya
REFNo: HS5328ES

1. To assess the current practices with left-over samples in hospitals and the attitude, willingness, and acceptability of stakeholders towards biobanking.
2. To audit human resources, laboratory infrastructure, governance, and data systems to understand available resources to support the establishment of left-over sample biobanks in health facilities
3. Undertake a detailed analysis of costs that will be needed to sustain operational activities on a yearly basis for either a federated or centralised approach of biobanking left-over samples in Uganda and Kenya
4. Assess the regulatory environment and engage relevant national regulatory bodies to adapt guidelines for left-over sample biobanking in Uganda and Kenya.


 Uganda 2024-12-10 16:00:04 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Tukwasibwe
ID: UNCST-2022-R011535
 Surveillance of P. falciparum Drug and Diagnostic Resistance in Refugee Populations
REFNo: HS5230ES

To conduct comprehensive malaria molecular surveillance in refugee populations to generate high quality molecular, epidemiological and entomologic data for monitoring geographic and temporal trends and thereby inform interventions to best protect refugee and local host populations.
Uganda 2024-12-10 15:59:04 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jude  Nicholars Iyke
ID: UNCST-2023-R007962
 THE EFFECTS OF PERSONALITY TRAITS ON THE ACCEPTANCE OF BIOMETRIC CONTROLLED HEALTH INFORMATICS IN PUBLIC HOSPITALS IN UGANDA
REFNo: SIR430ES

The purpose of this sequential mixed-method design study is to assess the relationship between the personality traits and acceptance of Biometric Controlled Health Informatics in Gulu and Soroti Regional Referal public Hospitals in Uganda that will help health strategists and policy makers evaluate how the personality traits of health workers affect their acceptance of biometric controlled health informatics (BCHI) for secure access for clinical and non-clinical health workers to patient records in public hospitals in Uganda . ,To examine how personality traits affect the acceptance of Biometric Controlled Health Informatics in these public hospitals using the acceptance model that was developed for that purpose,To determine the connection between acceptances of Biometric Controlled Health Informatics and personality traits in these public hospitals.,To establish health workers’ awareness of Biometric Controlled Health Informatics in these public hospitals,
 Nigeria 2024-12-10 15:54:44 2027-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Susan Nayiga
ID: UNCST-2020-R014642
 Managing AMR: Everyday experience with antibacterial drug resistant infections in central Uganda
REFNo: SS3469ES

1. To track the trajectories of illness, care, recovery or decline of patients diagnosed with antibacterial drug resistant infections.
2. To link the social, economic and illness histories and opportunities of patients with their onward trajectories with antibacterial drug resistant infections
3. To identify equity dimensions of the how systems manage antibacterial drug resistant infections and points for intervention to support recovery

 Uganda 2024-12-10 15:53:27 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Kakooza
ID: UNCST-2024-R002803
 Evaluation of capture enrichment for viral sequencing in a remote setting in Uganda.
REFNo: HS5270ES

Objective 2: Evaluate Analytical Performance in Uganda. NGS testing of blood samples from confirmed clinical cases and suspected clinical samples will be conducted. This includes de-identified archived blood samples collected from a sepsis cohort among participants who consented for their samples to be used for future research related to sepsis in Fort Portal, Uganda, at Fort Portal Regional Referral Hospital, which has enhanced biosafety capabilities. ,Objective 1: Develop and Optimize NGS Platform To pilot the use of a field-deployed portable next-generation sequencing for testing of archived sepsis blood samples in Uganda to search for hantavirus or bunyavirus infections. The project plans to field test the Oxford Nanopore Technologies (ONT) platform with archived blood samples. Phylogenetic trees will be developed, and virus clades and variants or new viruses will be described. The performance of enriched-NGS to detect the virus will be compared to index testing with RT-PCR when there are 5 or more positive results.,
 Uganda 2024-12-10 15:52:01 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anke Weisheit
ID: UNCST-2024-R004890
 ETHNO BOTANICAL SURVEY OF MEDICINAL PLANTS USED IN THE TREATMENT OF WOUNDS IN GULU DISTRICT
REFNo: SS2928ES

To investigate the preparation and application methods of these medicinal plants for wound healing purposes.,To identify and document medicinal plants used by the local communities in Gulu district for treating various types of wounds.,The aim of this study is to conduct an ethnobotanical survey to document the traditional knowledge and use of medicinal plants for treating wounds among the communities in Gulu district, Uganda.,
 Germany 2024-12-10 15:50:43 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Nakayenga Mutesi
ID: UNCST-2024-R004951
 Global Corridor, Urbanisation, Everydaylife and Techno-social Differentiation
REFNo: SS2860ES

2. To explore the everyday assembling of Corridor Urbanization to assess how investment in infrastructure is generating intra-urban and inter-urban relations/material connections between urban regions., To explain the global, urban geography of infrastructural corridors in reshaping the urbanization process in order to set a new agenda for global research,3. To investigate the everyday experiences of Corridor Urbanization within urban regions in order to understand the differentiated ways in which infrastructure is operated and accessed,1. To assess the global, urban geography and selected history of new corridors and the ways these projects are assembled in order to understand the role of urban regions,The aim of GlobalCORRIDOR is to address the challenge of how we understand Corridor Urbanization and to assess how these infrastructure led transformations are shaping urban inequality, as an everyday experience of techno-social differentiation,
 Uganda 2024-12-10 15:50:00 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
 OPTIMIZATION, VALIDATION AND ASSESSMENT OF FEASIBILITY AND ACCEPTABILITY OF HPV TESTING USING CODA
REFNo: HS4734ES

To develop and establish a novel rapid multi-modal algorithm (CANOPY) for screening and treatment of cervical cancer integrating multiple (CODA, VIA, ML) screening modalities to improve diagnostic yield. ,To gather design feedback to improve CODA workflow and device design, and refine CODA device, assay, and workflow using this critical feedback provided by Ugandan stakeholders,To evaluate the feasibility and acceptability of CODA in a clinical setting in Uganda based on feedback from clinical, public health, and patient stakeholders,To evaluate HPV testing using CODA in comparison to other (VIA, ML, ATILA System) devices for clinicians and patients engaged in community-based cervical cancer screening. ,To determine the diagnostic accuracy of CODA a clinical setting, using FP rate and comparison with gold-standard HPV tests and cytology,We will optimize, validate and assess the feasibility and acceptability of HPV testing using CODA and develop and validate a multimodal cervical cancer screening algorithm to optimize diagnostic yield (CANOPY).,
 Uganda 2024-12-10 15:49:00 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anxious   Niwaha Jackson.
ID: UNCST-2023-R008010
 Investigating the pancreas pathology underlying Lean Sub Saharan African Diabetes in Uganda
REFNo: HS5340ES

a. To compare the beta cell mass in pancreata obtained at autopsy in lean diabetes cases
versus lean controls
b. To evaluate the degree of pancreatic immune infiltration (Insulitis) in lean diabetes cases
and lean controls
c. To quantify the degree of misfolded protein stress in pancreata obtained at autopsy in lean
diabetes cases and lean controls
d. To evaluate beta cell dedifferentiation in lean SSA diabetes
e. To examine the exocrine pancreas for chronic pancreatitis and pancreatic duct calcification
in pancreata obtained at autopsy in lean diabetes cases versus lean controls
f. To determine the concentration of POPs in pancreata obtained at autopsy in lean diabetes
cases and lean controls.
g. To establish a pancreata and related tissue (blood and mesenteric fat) platform to enable
further studies related to diabetes and other metabolic diseases.

 Uganda 2024-12-10 15:47:20 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Implementation and evaluation of peer support and navigation supported by Project ECHO for patients with cancer in Uganda
REFNo: HS5297ES

6. To evaluated perceived program feasibility, acceptability, and appropriateness through surveys and exit in-depth interviews with peer navigators, patients, and UCI oncologists,5. To adapt the Cancer Behavior Inventory (CBI-B) self-efficacy scale, Edmondton Symptom Assessment Scale (ESAS), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ C30) quality of life for cancer patients questionnaire to the Uganda context by soliciting feedback from UWOCASO members and UCI oncology and palliative care specialists,4. To evaluate program impact by measuring patient self-efficacy, symptom burden, and quality of life using the above adapted scales at enrollment, 1, 3, 4 and 6 months after the program start ,3. To evaluate program impact by comparing the proportion of patients who completed treatment for early stage disease and or had treatment adherence of > 6 months in case of metastatic disease among patients matched with peer support and navigation right away versus six months later. ,2. To pair 100 cancer survivors with 200 matched patients with cancer in the Kampala, Wakiso, and Gulu districts of Uganda for peer support and navigation. Half of the selected patients will be randomized to be matched to peer support immediately, and half six months later . ,1. To provide refresher training in peer support and navigation to 100 cancer survivors. We will focus on the five most common cancers in Uganda (breast, cervical, prostate, Kaposi sarcoma, Non-Hodgkin lymphoma).,
 Uganda 2024-12-10 15:46:22 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ELIZABETH KYAZIKE
ID: UNCST-2023-R005557
 The Lasting Scars of War: Understanding the Socio-environmental Impact of Changing Global Commodity Chains in East Africa During the Second World War, 1937-1962
REFNo: SS3146ES

General Objective
The project's general objective is to document the impact of World War II on the Lake Victoria-area environment in the immediate (wartime) and midterm (into the post-war period) periods.
Specific Objective
Specifically, the project seeks to:
1) Evaluate the changes in environmental patterns of use (agricultural use, resource extraction, etc.) during the Second World War and its socio-environmental impacts.
2) Examine how the linkages between Africa (affected population), Great Britain (colonial power and prosecutor of war) and Switzerland (experts and trading companies) drove environmental change.
3) Analyze how global patterns were evident in the Lake Victoria region, in particular in relation to sustainable practices and cultures.

 Uganda 2024-12-10 15:43:59 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
DANIEL KIIZA
ID: UNCST-2024-R004044
 Development and Validation of a Machine Learning Prediction Model for Early Mortality among patients with HIV-Associated Cryptococcal Meningitis in Uganda
REFNo: HS5103ES

Primary Objectives: 1. To develop a machine learning model for the prediction of early mortality among patients with HIV-CM co-infection. 2. To validate a machine learning model for the prediction of early mortality among patients with HIV-CM co-infection. Exploratory Objective: 3. To develop and validate a machine learning model for the prediction of mortality (as a continuous outcome) among patients with HIV-CM co-infection.
 Uganda 2024-12-10 15:42:48 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Silvia Awor
ID: UNCST-2019-R000591
 PREDICTORS OF USE, PHYTOCHEMICAL PROFILES AND ANTISICKLING ACTIVITIES OF HERBAL MEDICINES FOR TREATING SICKLE CELL DISEASE IN ACHOLI SUB-REGION
REFNo: HS5030ES

2. To document the herbal medicines used for treating sickle cell disease in AchTo determine the anti-sickling activity of aqueous crude extracts of herbal medicines for sickle cell treatment in the Acholi sub-region. ,To assess the phytochemical profiles of selected herbal medicines used for the treatment of sickle cell disease in Acholi sub-region,To document the herbal medicines used for treating sickle cell disease in Acholi sub-region,To determine the predictors of the use of herbal medicines for the treatment of sickle cell disease in Acholi sub-region,To assess the predictors of use and antisickling activities of herbal medicines used for treating sickle cell disease in the Acholi sub-region of northern Uganda,
 Uganda 2024-12-10 15:41:38 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Abbas Mugisha
ID: UNCST-2023-R007013
 Internally displaced persons and psychosocial challenges of females at Muhokya IDP, Kasese district, Ugands
REFNo: SS3392ES

i)To identify the psychosocial challenges experienced by internally displaced females at Muhokya IDP camp
ii)To explore the coping mechanisms employed by internally displaced females to manage the psychosocial challenges at Muhokya IDP camp
iii)To explore the redress mechanisms available for the psychosocial challenges faced by internally displaced females at Muhokya IDP camp
iv)To propose recommendations on how to best assist internally displaced females overcome their challenges at Muhokya IDP camp
 Uganda 2024-12-10 15:26:35 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
ARTHUR EMORU
ID: UNCST-2024-R003421
 PREVALENCE AND FACTORS ASSOCIATED WITH CHRONIC POST-SURGICAL PAIN AMONG PATIENTS THAT RECEIVED AMBULATORY INGUINAL HERNIA SURGERY AT KYABIRWA SURGICAL CENTER
REFNo: HS5068ES

To determine factors associated with chronic pain after inguinal hernia repair among adult patients at Kyabirwa Surgical Center,To assess the prevalence of chronic pain after inguinal hernia repair among adult patients at Kyabirwa Surgical Center,To determine the prevalence of and factors associated with chronic pain after inguinal hernia repair in Kyabirwa Surgical Center’s adult patient population,
 Uganda 2024-12-10 15:25:15 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Orace David Tom
ID: UNCST-2024-R003113
 Students’ Loan Financing Scheme and Completion of STEM based Programmes in Public Universities in Uganda
REFNo: SS3353ES

i). To explore the nature of students’ loan financing scheme in public universities in Uganda
ii). To assess the completion of STEM based programmes by students on loans scheme in public universities in Uganda
iii). To evaluate the perceptions and experiences of STEM students regarding the impact of students’ loan scheme on their completion in public universities in Uganda
iv). To establish the relationship between students’ loan financing scheme and completion of STEM based programmes in public universities in Uganda

Uganda 2024-12-10 15:23:45 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
Stevens Bechange
ID: UNCST-2022-R009190
 Understanding Access to Business Financing for Young Entrepreneurs with and without Disabilities in Urban Uganda
REFNo: SS3471ES

The specific objectives will be:
1. To identify the different types of business financing options accessible by and preferred by young enterpreneurs with and without disabilities including what drives them to use these options.
2. To understand existing barriers for young enterpreneurs with and without disabilities in accessing and using the different business financing products, what can be done to address these and recommendations for more widespread access.
3. To describe how financial products from the RISE/E Programme affect young enterpreneurs with and without disabilities and their businesses and how they can be further improved.
4. Develop a database that includes demographic, socio-economic; and business financing information to facilitate the evaluation of success or failure with access to finance.

Uganda 2024-12-10 15:17:09 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
DORAH NAMPIJJA
ID: UNCST-2022-R009694
 Improving heart failure self-care with short, structured telephone calls in Uganda (HEART-CALLS)
REFNo: HS5307ES

To improve heart failure self-care through feasible and acceptable short, structured telephone calls in Uganda
Uganda 2024-12-10 15:16:13 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Transformative approaches to rapidly and efficiently test demand creation interventions to promote HIV retesting in adults at increased risk of HIV The Innovative Behavioral Intervention Strategies Megatrial (IBIS-Megatrial) Study
REFNo: HS5319ES

Aim 1. Adapt behavioral economics interventions to promote HIV retesting using a participatory prototyping approach in rural Kenya and Uganda.
Aim 2. Determine the effectiveness of many behavioral economics interventions to promote HIV retesting among high-risk adults in a multi-arm randomized trial.
Aim 3. Estimate heterogeneous treatment effects and identify optimal demand creation interventions.

 Uganda 2024-12-10 15:15:04 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Sub-Study C – “Evaluation of Host-Response and/or Pathogens from Biospecimens Collected with a Capillary Blood Collection TASSO that Minimizes Pain Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS5332ES

1) Identify pathogens collected via the minimal pain Tasso collection device and those
collected via venipuncture (0 Hour and Day 28 of the main study)
2) Identify host-response biomarkers collected via the minimal pain Tasso collection device
and those collected via venipuncture (0 Hour and Day 28 of the main study)
3) Evaluate the correlation between host biomarkers and pathogens collected via the
minimal pain Tasso collection device to those collected via venipuncture at two study
visits (0 Hour and Day 28 of the main study)
4) Evaluate collection failure rates with the Tasso device

Uganda 2024-12-10 15:13:26 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Naheem Tijani Adekilekun
ID: UNCST-2022-R010325
 Biogenic synthesis of silver nanoparticles from Termitomyces sp. and their antimicrobial activity against clinical samples of resistant pathogenic Candida species
REFNo: HS5244ES

i. To synthesize silver nanoparticles (AgNPs) by employing the metabolites of Termitomyces species;

ii. To characterize the AgNPs biosynthesized and establish the phylogeny of Candida species using molecular techniques;

iii. To determine the antimicrobial activity of the fabricated AgNPs in contrast to common antifungal agents against resistant pathogenic Candida species.

 Nigeria 2024-12-10 15:11:28 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 STANDARD Q Syphilis Ab Test – Validation of Specimens
REFNo: HS5333ES

The objective of this study is to demonstrate the equivalence of serum, venous whole blood (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin), plasma (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin) and fingerprick whole blood on the STANDARD Q Syphilis Ab Test according to WHO TSS-6 Part 1: 1.2.1.
 Uganda 2024-12-10 15:09:47 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rose Nakasi
ID: UNCST-2022-R010805
 Automated Mobile Microscopy for Tuberculosis Diagnosis in Uganda
REFNo: SIR450ES

1. Create an open, labelled, inclusive dataset for digital sputum microscopy images collected from the Ugandan population,
2. Develop a machine learning aided point-of-care learning platform for digital sputum microscopy image acquisition and interpretation.
3. Develop machine learning models for automatic recognition of TB bacilli features in digital sputum microscopy images,
4. Integrate the developed models in a decision support web application,
5. Validate the developed system in a clinical study.

 Uganda 2024-12-10 15:02:13 2027-12-10 Engineering and Technology Non-Clinical Trial Non-degree Award
Yasushi Miyauchi
ID: UNCST-2023-R005483
 Analysis of excitatory amino acids in Ustilago maydis of maize and sorghum in northern Uganda.
REFNo: A475ES

To measure the amount of each excitatory amino acid contained in Ustilago maydis of maize and sorghum by using Gas Chromatography,
 Japan 2024-12-10 15:01:21 2027-12-10 Agricultural Sciences Non-Clinical Trial Degree Award
Saidah  Menya
ID: UNCST-2024-R003540
 Improving quality maternal and new-born care: An investigation into the relevance and effectiveness of quality care processes in three health facilities with in Nakaseke and Luwero districts in Uganda
REFNo: HS5038ES

4. To evaluate whether the quality improvement process improves maternal and newborn outcomes. ,3. To establish a baseline data and evaluate whether the quality improvement process increases quality of care scores in three health facilities and compare with the baseline,2. To implement and monitor the quality improvement tool and relevant processes and gather feedback on their relevance and utility in the AdaraNewborn facilities.,1. To develop a quality improvement process within all AdaraNewborn facilities, including a quality improvement tool that prioritise the WHO maternal and newborn health standards,To monitor and assess the implementation of quality improvement processes to evaluate whether they contribute to improved quality of care within a health facility and overall maternal and newborn outcomes.,
 Uganda 2024-12-10 14:58:15 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muriel Mac-Seing
ID: UNCST-2024-R005208
 Invisibility of disability in Global South and North: Equitable access to health services in the context of climate change
REFNo: SS3507ES

To strengthen research collaboration and solidarity through co-creation, trust-building, and inclusive co-learning between partners and researchers from Uganda and Canada.,Considering the results of the above objective, to further explore the perspectives of relevant intersectoral actors on the relationships between access to health services for women and men with disabilities, including access to veterinary services for their animals, and climate change in Québec, Canada, and Gulu District, Northern Uganda.,To identify key priority research areas through a scoping review that will synthesise the existing literature and identify research gaps in the relationships between access to health services for PWD, including access to veterinary services for their animals, and climate change.,To explore the perspectives on the relationships between access to health services among women and men with disabilities and climate change in the Global South and North.,
 Canada 2024-12-10 14:56:23 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deo Nsamba
ID: UNCST-2024-R004495
 INNOVATIVE ALTERNATIVE INTERIOR DECORATES AND EXECUTION OF SEMI ABSTRACT LANDSCAPE MONUMENTS AT KABALE UNIVERSITY
REFNo: SIR319ES

i. To assess areas with quality clay around Kabale using a pilot study in developing innovative interior decorates and semi abstract landscape monuments
ii. To identify and analyze the characteristics and properties of selected clays in the laboratory of civil engineering Kabale University. for use in developing innovative interior decorates and semi-abstract landscape monuments.
iii. To explore and develop creative techniques for transforming the selected local clays into innovative interior decorates and semi abstract landscape monuments.
iv. To execute and evaluate the effectiveness of the developed interior decorates and semi abstract landscape monuments in enhancing aesthetic appeal, functionality and sustainability.
Research questions


i. How will quality clay around Kabale be assessed in developing an innovative interior decorates and semi abstract landscape monuments.
ii. What type of selected local clays will be identified and analyzed through their characteristics and properties in Kabale for use in developing innovative interior decorates and semi abstract landscape monuments?
iii. What suitable techniques will be explored and developed to have creative techniques that will transform the selected local clays into innovative interior decorates and semi abstract landscape monuments?
iv. How will creative innovative approaches of innovative interior decorates and semi abstract landscape monuments be executed and evaluated?

Uganda 2024-12-10 14:54:46 2027-12-10 Engineering and Technology Non-Clinical Trial Non-degree Award
Sarah Lewinger Julianne
ID: UNCST-2024-R004045
 Prayer, Poetry, and Protest: Pentecostalism and Political imagination among Ugandan Youth
REFNo: SS2594ES

The primary objective of this research project is to investigate how young people in Kampala, Uganda, aged eighteen to thirty-five, mobilize charismatic Christian discourses, practices, and communities to imagine their futures, engage with politics, and navigate conditions of political repression, economic precarity, and social disintegration. Specifically, the project aims to:
1. Explore the diverse ways in which young people draw upon charismatic Christianity as a resource for making sense of their lives, asserting their dignity, and envisioning alternative social and political possibilities.
2. Examine how young people's "god-talk" – a critical and creative method of biblical reinterpretation and intimate conversation with the divine – challenges conventional understandings of the political and expands notions of political agency and engagement.
3. Investigate the role of social memory in shaping contemporary youth political imaginations, by considering how young people's religious-political expressions both draw upon and depart from earlier movements, such as the Holy Spirit Movement.
4. Identify and analyze the spaces, practices, and cultural forms through which young people develop and express their political subjectivities, with a focus on artistic and creative practices, such as spoken word poetry and music.
5. Contribute to anthropological debates on the complex and often contradictory role of religion in social movements, as well as the ways in which marginalized youth navigate and challenge the constraints of their political contexts.
This project aims to generate new insights into the religious and political imaginations of urban Ugandan youth, and to shed light on the diverse and unexpected ways in which young people are actively engaging with politics outside of the formal political sphere. By taking seriously the political significance of religious and artistic imaginaries, this research has the potential to expand our understanding of what constitutes the political and to contribute to broader debates about youth agency, social movements, and the role of religion in public life.
USA 2024-12-10 14:52:31 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
PREETI KUMARI
ID: UNCST-2024-R001852
 Science Laboratory Operationalization, Secondary School Students’ Academic Attitude, Motivation, and Performance in Mbarara City, Uganda
REFNo: SS3434ES

1. To assess the conditions of science laboratories in secondary schools in Mbarara City, Uganda, to get a ground-level reality check.
2. To examine the relation between science laboratory operationalization and student’s attitude towards science.
3. To investigate the effect of science laboratory operationalization on motivation in choosing science as a career.
4. To relate the science laboratory operational conditions to students' performance in science education.
5. To study the mediation effect of student’s attitude and motivation in science subjects on performance.

 India 2024-12-10 14:47:47 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
sandra etumah omon
ID: UNCST-2024-R003992
 Assessment of the Nutritional Profile and Biochemical Adaptation of Zea mays L. Grown around Kilembe Mining Area, Kasese, Uganda
REFNo: NS809ES

1. To assess the Physicochemical characteristics of the soil and heavy metal content such as copper, lead, cobalt, Nickel, Cadmium, Mercury, chromium, and arsenic at the research site.
2. To analyze the heavy metals content (copper, lead, cobalt, Nickel, Cadmium, Mercury, chromium, and arsenic) of the maize plant grown at the mining site and their translocation.
3. To analyze the nutritional profile: proximate analysis (carbohydrates, protein, fats/oil, crude fiber, moisture, and ash), mineral element (iron, magnesium, manganese, calcium, sodium, phosphorus, sulfur, and potassium), and Vitamins (thiamine, niacin, riboflavin, retinol, cobalamin, pyridoxine, tocopherol, ascorbic acid, and cholecalciferol) of the maize grown around the mining site.
4. To assess the oxidative stress markers (malondialdehyde, tocopherol, and proline) and the enzymatic antioxidant capacity (glutathione peroxidase, superoxide dismutase, and catalase) in the leaves during the vegetative stage of the maize plant.
5. To quantitatively determine the hormonal levels (ABA, auxins, and brassinosteroids) in the leaves during the vegetative stage of the maize
6. To determine bioremediation options from the culturable rhizospheric soil bacteria isolated from around the mining site.

 Nigeria 2024-12-10 14:44:20 2027-12-10 Natural Sciences Non-Clinical Trial Degree Award
Maria Magdalene Namaganda
ID: UNCST-2021-R004319
 Development of a machine learning model for prediction of virological failure in a resource-limited setting
REFNo: HS3982ES

Sub-study 1 To identify the risk factors associated with virological failure among PLWH in east Africa from 2014 to 2024. Sub-study 2 To analyse the trends of ART use and incidence of virological failure rates among PLWH in TASO-Uganda health centres from 2014 to 2024. Sub-study 3 To develop and validate machine learning models for prediction of virological failure. Sub-study 4 To evaluate the practical utility of the HIV virological failure predictive models developed in a clinical setting.
Uganda 2024-12-10 14:40:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackson Orem
ID: UNCST-2021-R012016
 A Phase III, Randomized, Open-Label, Non-Inferiority Study of Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma in Resource-Limited Settings
REFNo: HS4073ES

To describe the incremental cost-effectiveness ratio per QALY gained (as assessed by PROPr) between PLD and PTX,To assess quality of life across PROMIS domains (i.e., cognitive function, physical function, fatigue, pain interference, depressive symptoms, anxiety, ability to participate in social roles and activities, and sleep disturbance) with the PROPr tool at start of therapy, mid-treatment, and after treatment with PLD and PTX ,To describe the cost of therapy across AMC sites in sub-Saharan Africa to deliver both PLD and PTX by micro-costing analysis for goods and time-in-motion analysis for services. ,To estimate the objective response rate (defined as the sum of complete and partial responses) for AIDS-KS, response duration and overall survival in each treatment arm. ,To evaluate whether there is sufficient evidence to conclude that PLD is non-inferior to PTX in people with severe AIDS-associated KS receiving concomitant ART in resource-limited settings. ,
 Uganda 2024-12-10 14:39:24 2027-12-10 Medical and Health Sciences Clinical Trial Non-degree Award
Adelline Twimukye
ID: UNCST-2019-R000117
 HIV CARE AND ANTENATAL HEALTH SEEKING BEHAVIOUR PATTERNS OF PREGNANT AND BREAST-FEEDING WOMEN DURING PREVIOUS COVID-19 PANDEMIC IN UGANDA
REFNo: SS3219ES

To document the challenges faced by pregnant and breastfeeding women with HIV in accessing healthcare services in the COVID-19 period.,To interrogate the effects of COVID-19 pandemic to adherence to routine clinic appointments and antiretroviral therapy (ART) among pregnant and breast-feeding women living with HIV.,To examine the social or cultural norms that influence access to care among pregnant or breast-feeding women HIV during the COVID-19 pandemic.,To investigate health care worker’s knowledge, attitude, and practices about COVID-19 among pregnant and breast-feeding women living with HIV in Uganda.,The purpose of the study is to explore HIV care and antenatal seeking behavior patterns of pregnant and breast-feeding women during response and control of COVID-19 pandemic in Uganda.,
 Uganda 2024-12-10 14:37:39 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
VICENT MWESIGYE
ID: UNCST-2024-R002866
 LYMPHEDEMA: CAUSATIVE AGENTS, PATIENT AND CARETAKER KNOWLEDGE, SELF-REPORTED HEALTHCARE NEEDS AND PREVENTIVE STRATEGIES IN KAMWENGE DISTRICT.
REFNo: HS5335ES

3. To explore the lymphedema-related knowledge, lived experiences and healthcare needs of patients and their caretakers and preventive strategies in Kamwenge district, South Western Uganda.,2. To determine the causative agents of lymphedema among patients with lymphedema in Kamwenge district, South Western Uganda.,1. To describe the Preventive strategies, their effectiveness in patients with Lymphedema based on Scoping review globally.,To determine the causative agents, patient and caretaker knowledge, self-reported healthcare needs and preventive strategies amongst Lymphedema patients in Kamwenge District South Western Uganda.,
 Uganda 2024-12-10 14:35:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Tess Lallemant
ID: UNCST-2023-R007159
 How do Firms Hire? A Demand-Side Experiment to Reduce Matching Frictions in Uganda Labor Markets
REFNo: SS3487ES

1. Answer the research question: How do firms navigate the hiring process for graduate workers?
2. Answer the research question: How are firms identifying their employment needs?
3. Answer the research question: How are firms communicating their employment needs?
4. Answer the research question: To what extent are these hiring frictions affecting match quality?
5. Answer the research question: Do firms learn about hiring and adapt their search strategies to achieve higher match quality?
 USA 2024-12-10 14:24:53 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Optimizing the Implementation and Scale-Up of the WHO Treatment-Decision Algorithms for Children with Pulmonary Tuberculosis in Sub-Saharan Africa (OPTIC-TB)
REFNo: HS5246ES

1) To compare the effectiveness of TDA versus the Standard of Care strategies in routine non-research programmatic conditions.
2) To identify processes and contextual factors that influence the effectiveness and fidelity in the implementation of TDA.
3) To compare the costs, cost-effectiveness, and population-level impact of the TDA strategies on the burden of TB.
4. To estimate/validate the diagnostic performance (sensitivity, specificity, negative and positive predictive values) of the TDAs for TB in children under 10 years old in various healthcare system settings and in various clinical contexts (i.e, such as HIV, malnourished children, facility level, gender, rural, urban etc.

Uganda 2024-12-10 14:06:31 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vianney Tushabe John
ID: UNCST-2024-R015708
 Development of Multiplex Molecular Test for S. mansoni and P. falciparum Duplex using LAMP assay and Pit Latrine metagenomic sampling for community assessment
REFNo: SIR445ES

- Development of the Multiplex Malaria – Schistosomiasis assay
- Latrine Metagenomics for community diagnostics assessment 
- Validation of Molecular duplex assay technology 
 Uganda 2024-12-10 14:04:09 2027-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Manon Delvaux Alizee
ID: UNCST-2024-R002311
 Cultivating Cooperation: The Impact of Formalizing Land Rental Contracts on Refugee-Host Interactions and Agricultural Production in Rural Uganda
REFNo: SS3408ES

In northern Uganda, food insecurity is high for many refugees, who cultivate land for their subsistence in the vicinity of the settlements. A large majority of these refugees do not have a formal written land rental contract with their landlords. While informal institutions and agreements can have enforcement power in socially and culturally homogeneous groups, their efficiency tends to decrease with social and cultural distance. In this setting of cohabitation between Ugandans and refugees, the absence of clearly defined terms of trade often limits successful farming outcomes, as refugees’ rights to what they earn, produce, and consume are more vulnerable to changes. Suggestive evidence indicates that formal land contracts grant greater security, which can lead to increased farm profitability, investment and credit opportunities, and greater economic diversification and growth.

We will conduct a randomized pilot evaluation to measure the impact of formalized land rental contracts between refugee tenants and host community landlords. In the treatment groups, the landlords and tenants will receive support to formalize their land rental agreement. In the control group, landlords and tenants will remain with verbal and informal land rental agreements. We will evaluate indicators such as trust, social cohesion, agricultural practices, and food security. The study will also investigate why formalized land rental contracts are not more widespread in rural Uganda. The sample will include tenants from the Bidibidi, Imvepi and Rhino refugee settlements and landlords from the host communities.
 France 2024-12-10 14:03:00 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
SAM ALI
ID: UNCST-2020-R014824
 A Noncontact Bed-Based Platform for Passive Longitudinal Monitoring of Maternal and Fetal Cardiovascular Physiology in Uganda
REFNo: HS5320ES

Main objective
• To monitor maternal and fetal heart rate, respiratory rate, fetal movement, and sleep patterns among selected pregnant women enrolled in the iTECH study using noncontact bed sensors with the goal of better understanding both maternal and fetal physiology.

Specific objectives
1. To describe the maternal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
2. To describe the fetal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
3. To demonstrate the feasibility of measuring and extracting fetal movement signals among selected pregnant women enrolled into the iTECH study.
 Uganda 2024-12-09 13:22:54 2027-12-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Disentangling the population structure of MRSA in an urban low-income settings
REFNo: HS4699ES

1. To define the population structure of MRSA in hospital and community settings in Kampala, and identify risk factors for MRSA carriage among inpatients and individuals in the community.

2. To Investigate the probable coexistence between HA-MRSA and CA-MRSA in hospital and community in Kampala.
 Uganda 2024-12-02 17:33:35 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brian Turigye
ID: UNCST-2021-R012569
 QUALITY OF MATERNAL AND NEWBORN CARE; A CASE STUDY OF KASESE AND BUNDIBUGYO DISTRICTS, MIDWESTERN UGANDA
REFNo: HS5213ES

1. To describe existing evidence on the quality of Provision of Obstetric and newborn care in Uganda
2. To establish the quality of provision of Obstetric and newborn care in Midwestern Uganda
3. To explore the determinants and drivers of the quality of provision of Obstetric and newborn care in Midwestern Uganda
4. To analyze critically the existing strategies on improving the provision of Obstetric and newborn care in Midwestern Uganda and develop relevant alternatives

 Uganda 2024-12-02 17:32:38 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 Lively Minds Together Range and Listenership Estimation
REFNo: SS3435ES

To gather data on the signal strength of radio programs of interest,To provide evidence-based recommendations on geographic locations and radio programming for the future rollout and evaluation of the Lively Minds Together project.,To understand preferences, popularity, and other media sources related to radio programming.,To collect general information on radio listenership habits.,To gather data on the number of listeners for the radio programs of interest.,
 Uganda 2024-12-02 17:31:19 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Idris Sanusi
ID: UNCST-2024-R003856
 EVALUATION OF THE CONCENTRATIONS OF PHARMACEUTICALS AND HEALTH RISK ASSESSMENT IN GROUND AND SURFACE WATERS IN KAMPALA AND MBARARA REGIONS OF UGANDA
REFNo: HS5235ES

I. To assess the physicochemical parameters (pH, water temperature, electrical conductivity, total dissolved solids, total suspended solids, total solids, chlorides, nitrate, phosphate and sulphate) in the collected water samples from the selected areas as pollution indices. II. To determine the concentrations of iron, copper, mercury, cadmium, manganese and lead in surface water and groundwater of the study regions. III. To determine the concentrations of the pharmaceuticals (sulfamethoxazole, ciprofloxacin, ibuprofen, amoxicillin, cotrimoxazole, metronidazole, artemether/lumefantrine, acetaminophen, caffeine, and carbamazepine) in surface water and groundwater of the study regions. IV. To assess the spatio-temporal variation of heavy metals and pharmaceuticals in the water samples collected from the regions. V. To assess the health risks associated with the exposure to pharmaceuticals and heavy metals in the water samples collected.
Nigeria 2024-12-02 17:29:38 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Ibrahim Kasujja
ID: UNCST-2021-R013169
 Food Insecurity and Mental Health among Children and Adolescents: Mixed Methods Study in Uganda
REFNo: HS4997ES

Objectives:

(1) to conduct a formative qualitative study to explore the children’s and teachers’ perceptions of food insecurity experiences and child and adolescent mental health
(CAMH) to ultimately build a framework which links food insecurity and CAMH in schools in Uganda,

(2) to conduct a reliability and validation study to assess the psychometric properties of the day scholars food insecurity experience scale (DSFIES) by examining test-retest reliability and criterion validity in
schools in Uganda, and

(3) to conduct a prospective cohort study to unpack the causal mechanisms linking food insecurity and CAMH by examining bidirectional temporal associations among seven to 13 years old children in Uganda.
 Uganda 2024-12-02 17:28:44 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Timothy Opobo
ID: UNCST-2023-R006042
 The Prevalence of Violence against Children in School and the Effectiveness of Reporting, Tracking, Referral and Response Mechanisms in Schools in Karamoja Sub-Region
REFNo: SS3414ES

1. Establish the prevalence and nature of VAC/VACiS among children, including their age, sex, grade, and vulnerability/disability status.
2. Identify, describe and quantify structures that children report cases of violence to when they occur
3. Identify existing mechanisms for referral, response and tracking cases of violence against children in schools?

 Uganda 2024-12-02 17:24:47 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 IMPACT OF THE UNLOCK LITERACY PROJECT MODEL ON THE READING RESULTS FOR GIRLS AND BOYS IN EARLY GRADES IN UGANDA
REFNo: SS3379ES

7. To find out the challenges to implementing the Unlock literacy model in primary schools,6. To determine the cost of the UL model in the Ugandan setting,5. To identify the key lessons so far learned during implementation of the UL model.,4. To establish whether the Unlock literacy model contributes to increased support by education authorities for children\'s reading,3. To assess the extent to which the Unlock literacy model interventions are influencing support by parents or guardians and communities for children\'s reading.,2. To establish whether the Unlock literacy model contributes to strengthened teaching instruction in Primary 1–3.,1. To determine the extent to which the Unlock literacy model contributes to increased reading results of children.,The main purpose of this study is to examine the impact of the UL Project Model on the reading results for girls and boys in early grades in selected World Vision implementing districts in Uganda.,
 Uganda 2024-12-02 17:21:46 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Salvatore Ssemmanda
ID: UNCST-2024-R004583
 KNOWLEDGE OF ALARM SIGNS OF STROKE AMONG CARETAKERS OF STROKE PATIENTS AND FIRST CONTACT HEALTH CARE PROVIDERS AT TWO TERTIARY REFERRAL HOSPITALS IN UGANDA
REFNo: HS5181ES

General objective.

To describe how well the alarm stroke signs summarized in the BE-FAST mnemonic are known by acute stroke patients’ caretakers and first contact stroke health care providers and how this knowledge by the acute stroke patients’ caretakers affects time of arrival of stroke patients to stroke services in the two major stroke referral hospitals in the country.

Specific objectives:

> To describe the knowledge of the BE-FAST acute stroke symptoms and signs by the first contact stroke health care providers in the two major stroke referral hospitals in Kampala, Uganda

> To describe the knowledge of the BE-FAST acute stroke symptoms and signs by the acute stroke patients’ bedside caretakers in the two major stroke referral hospitals in Kampala, Uganda.

> To demonstrate the relationship between knowledge of BE-FAST acute stroke alarm signs by stroke patient caretakers and time of arrival of their stroke patients to hospital stroke services in in
the two major stroke referral hospitals in Kampala, Uganda.
 Uganda 2024-12-02 17:19:44 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Obinna Barah Onyebuchi
ID: UNCST-2024-R002664
 Investigation of Tribomechanical Properties of Aluminium (AA6061) Reinforced with Hybridized Agro-Marine Waste for Automotive Applications
REFNo: SIR428ES

Main Objective
This research aims to investigate the tribomechanical properties of Aluminum (AA6061) reinforced with hybridized agro-marine waste particle composites (AMWPCs) for enhanced automotive applications.
Specific Objectives
1. To assess tensile, compressive strength, and hardness characteristics of AMWPCs for ascertaining the material\'s strength under various loading conditions, and resistance to indentation or scratching respectively.
2. To investigate flexural strength, impact, and fatigue resistance of AMWPCs under dynamic loading conditions.
3. To evaluate the tribological effects and wear resistance of AMWPCs in enduring wear and friction.
4. To examine the material\'s microstructure and elemental composition using FTIR, SEM/EDS.
5. To Analyze AMWPCs phase transitions and thermal stability using DTA, and TGA.
 Nigeria 2024-12-02 17:18:19 2027-12-02 Engineering and Technology Non-Clinical Trial Degree Award
Hannington Ngabirano
ID: UNCST-2024-R003312
 Improving Pesticide Use in Food Crop Growing in Kigezi Sub-Region in South-western, Uganda. RefNo: KABREC-2024-238
REFNo: NS873ES

2. Training farmers and dealers in agro-inputs on pesticide use in food crops in Kabale, Rukiga, Rubanda, Kisoro, Kanungu and Rukungiri Districts.,1. Investigate pesticide use in food crops in south-western Uganda,
 Uganda 2024-12-02 17:16:00 2027-12-02 Natural Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 NEOSEPSIS Project: Reducing neonatal and maternal mortality by rapid detection of sepsis in resource-limited environments
REFNo: HS5058ES

1) Explore and evaluate potential distribution channels and market entry strategies for the NeoSep SAA test. 2) Identify and analyze the barriers that may impede the widespread adoption of the NeoSep SAA test. 3) Determine the cost-effectiveness of implementing the NeoSep SAA test in clinical settings in healthcare resource limited settings and systems. 4) Assess the NeoSep SAA test’s performance as compared to CRP test. 5) Evaluate the applicability of the NeoSep SAA test for the detection of maternal sepsis occurring after the first five days of birth. 6) Assess the NeoSep SAA test’s utility in monitoring response to antibiotic therapy in neonates who have undergone treatment for sepsis.7) Evaluate the diagnostic performance of the optimized NeoSep SAA test for neonatal sepsis by evaluating its sensitivity, specificity, PPV, and NPV.
 Uganda 2024-12-02 17:12:10 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Katende
ID: UNCST-2023-R006954
 ASSESSMENT OF THE CURRENT STATE OF CHILD TRAFFICKING INTO WORST FORMS OF CHILD LABOUR IN NAPAK AND KAMPALA DISTRICT, UGANDA
REFNo: SS2547ES

i. To assess the current nature and dynamics of child trafficking in Napak and Kampala districts.

ii. To indentify the current key factors contributing to child trafficking in Napak district.

iii.To evaluate the community awareness and acceptance levels regarding child trafficking in Napak district.

 Uganda 2024-12-02 17:10:31 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 PROJECT MID TERM EVALUATION OF WATER SANITATION AND HYGIENE FOR SEXUAL REPRODUCTIVE HEALTH AND RIGHTS IN AMURU DSITRICT, NORTHERN UGANDA (PIWA Maleng II Project).
REFNo: SS3385ES

1.2 Purpose of the research study/study protocol
To highlight the evaluation process that will be followed during the mid-term evaluation that aims at determining the access and utilization of SRHR services among youths, establishing the barriers and enablers to SRHR services and establish the effect of integration of SRHR and WASH on Menstrual hygiene management among adolescents and youths in communities and schools in Lamogi and Pabbo sub counties in Amuru district.

1.3 Specific objectives of the mid-term evaluation
This mid-term evaluation will aim to achieve the following broad objectives;
i. Determine the level of access and utilization of SRHR services among adolescents and youths in target communities of Pabbo and Lamogi sub counties.
ii. Establish the barriers and enablers of SRHR services uptake among adolescents, youths and women at target communities in Lamogi and Pabbo sub counties.
iii. Establish the effect of integration of SRHR and WASH on Menstrual Hygiene Management among adolescents and youths in target communities and schools of Lamogi and Pabbo sub counties.

 Uganda 2024-12-02 17:09:15 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ivan Sserwadda
ID: UNCST-2022-R009568
 Respiratory Microbiome: insights into the diagnosis and pathogenesis of Tuberculosis
REFNo: HS4329ES

To understand the role of bacterial, viral and fungal colonization or infection (other than Mycobacterium tuberculosis) in pulmonary TB and in the clinical performance of potential TB triage tests.,To employ the Sanity Respiratory Pathogen Panel (RPP36) for culture and sensitivity testing to identify clinically relevant respiratory pathogens in presumptive tuberculosis patients,To determine the association of the respiratory microbiota and socio-demographic characteristics among presumptive and confirmed tuberculosis patients,To determine the correlation between the clinically significant microbiota and clinical presentation among presumptive and confirmed tuberculosis patients,To determine the clinically significant pathogens co-infecting the presumptive tuberculosis patients ,A systematic review of the respiratory microbiome changes in relation to Tuberculosis,
 Uganda 2024-12-02 17:07:10 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Betty Akurut Enyipu
ID: UNCST-2021-R013556
 Prevalence of Anxiety and Depression Among Students of Uganda Christian University
REFNo: SS3474ES

Development of Innovative Psychotherapy Models: The project will result in the development of group-based psychotherapy models specifically designed to address depression and anxiety among university students. These models will draw upon evidence-based practices while also incorporating culturally relevant elements to ensure effectiveness within the Ugandan context.,
 Uganda 2024-12-02 17:06:13 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
 ASSESSING THE KNOWLEDGE AND ATTITUDES OF CAREGIVERS TOWARDS PAEDIATRIC ORTHOPAEDIC SURGERY AT CORSU HOSPITAL
REFNo: HS5217ES

primary objectives;
-To assess the knowledge and attitude of caregivers towards paediatric orthopaedic surgery at CoRSU Hospital

Secondary Objectives
1. To determine the caregivers’ knowledge towards paediatric orthopaedic surgery at CoRSU hospital.
2. To determine the caregivers’ attitude towards pediatric orthopedic surgery at CoRSU hospital 3. To identify factors influencing caregiver decision-making in pediatric orthopaedic surgery
 Uganda 2024-12-02 17:05:18 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Affordances of makerspaces influencing biomedical undergraduate engineering students' design learning and curriculum localization in Uganda and the USA
REFNo: SIR448ES

Main Objective
To explore and compare how the affordances of the DesignCube makerspaces at Makerere University and Duke University influence biomedical engineering students' design learning and the localization of curriculum by the end of the study period.

Specific Objectives
1.To determine the perceived affordances of the DesignCube makerspaces among undergraduate biomedical engineering students at Makerere University and Duke University within the first four weeks of their engagement in the design coursework.

2.To assess the actual affordances of the DesignCube maker spaces after students’ full engagement with the prototyping and design coursework by the end of the academic term.

3.To identify the factors that foster or limit student engagement with the DesignCube makerspaces at Makerere University and Duke University by the completion of the study.

4.To evaluate how the affordances identified in each context (Makerere and Duke) inform the localization and adaptation of curriculum and pedagogy for design learning in biomedical engineering by the final stage of the study.
 Uganda 2024-12-02 17:04:31 2027-12-02 Engineering and Technology Non-Clinical Trial Non-degree Award
Abel Mucunguzi
ID: UNCST-2023-R006397
 LEVERAGING THE TEA VALUE ADDITION CHAIN PROJECTS FOR COMMUNITY DEVELOPMENT AND POVERTY REDUCTION: EVALUATING NAADS SUPPORT TO TEA INDUSTRY IN GREATER BUSHENYI, UGANDA
REFNo: SS3382ES

1.4.1 To ascertain the number of transformative community projects /value addition SMEs that have sprung up in the tea producing communities of Greater Bushenyi since the onset of NAADS assistance
1.4.2 To assess the socio-economic impact that has been realized from the transformative community projects /value addition SMEs that strung up in Greater Bushenyi since the onset of NAADS assistance
1.4.3 To establish the challenges/obstacles that have hindered the formation/operation of transformative community projects/value addition SMEs in Greater Bushenyi since the onset of NAADS assistance
1.4.4 To generate alternative approaches by which the government and partners (recipients) of NAADS assistance should have used in order to encourage more transformative community projects /value addition SMEs to spring up and grow in Greater Bushenyi

 Uganda 2024-12-02 17:03:29 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jacob  Mutazindwa Kasabunga
ID: UNCST-2024-R015547
 Agriculture and Livelihoods in Uganda
REFNo: SS3430ES

Main objective/ purpose
The purpose of the baseline study is to determine baseline values related to the current state of agricultural production, productivity, and the levels of access to commercialization facilities and to affordable and sustainable rural microfinance for value chain development in Uganda.

Specific Objectives
Specifically the baseline study aims: -
i. To assess the feasibility of investments in the coffee, rice, oil seed (sunflower and soybean), simsim (sesame), dairy (milk and milk products), and goats and sheep value chains to improve farmer incomes, and the feasibility of investments in cassava, maize and beans to improve food security as well as the cross-cutting themes of climate change as well as gender.

ii. To obtain qualitative data through conducting stakeholder interviews, facilitating focus group discussions, and obtaining quantitative data through a survey in targeted regions in Uganda.
iii. To assist in other research activities, including assisting the project team in identifying survey subjects that meet project inclusion criteria and respondents that can inform the feasibility study.
iv. To assist in piloting and refinement of data collection instruments and contribute to analysis to inform the Baseline Report and Feasibility Study

 Uganda 2024-11-27 15:38:15 2027-11-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stella Neema
ID: UNCST-2019-R000814
 Understanding the processes and acceptability of a child-friendly paediatric formulation of Praziquantel for the treatment of schistosomiasis among preschool-aged children in endemic districts in Uganda
REFNo: SS3420ES

The overall aim of this study is to analyse the factors surrounding the pilot introduction of arPZQ among PSAC in communities in Uganda at the macro, meso and micro levels.

Objectives

1. To evaluate the acceptance, appropriateness and perception of paediatric schistosomiasis treatment and distribution (delivery) among caregivers and other community members

2. To analyse the acceptance and perception of the paediatric praziquantel distribution methods among implementation personnel

3. To evaluate advocacy, social mobilisation and communication strategies and toolkits supporting the delivery of paediatric schistosomiasis treatment

4. To evaluate the pilot implementation of the weight-based dosing protocol


Uganda 2024-11-26 19:48:25 2027-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSEPHINE  BAYIGGA
ID: UNCST-2024-R003757
 Understanding preferred Tuberculosis Treatment adherence interventions among persons identified with Alcohol use Disorder in Kampala, Uganda: A mixed methods study
REFNo: SS3228ES

The study aims to elicit the preferred tuberculosis treatment adherence interventions among persons with alcohol use disorder in Kampala, Uganda,
 Uganda 2024-11-26 19:46:58 2027-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Improving end-of-life care for dying patients and their families in Ugandan ICUs
REFNo: HS4832ES

5. Synthesise the findings to produce recommendations for future end-of-life care in ICU practice, research and policy.,To explore clinicians’ experiences of end-of-life care provision in Ugandan ICUs and the use of person-centred outcome measures.,3. To utilise the Integrated Palliative care Outcome Scale (IPOS) staff version as a tool in identifying symptoms and important concerns at the end of life in ICU,2. To assess symptoms and important concerns at end=of-life in ICU using the integrated palliative care outcome scale ,1. To explore ICU clinician’s perspectives of factors influencing the provision of quality end-of-life care through a survey,To explore factors influencing the provision of end-of-life care in Ugandan ICUs test and evaluate the use of person-centred outcome measures in improving end-of-life care in dying patients and their families,
 Uganda 2024-11-26 19:41:46 2027-11-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Improving understanding of Capacity to consent to sensitive biomedical Research among adolescents in Rakai Uganda (ICARE)
REFNo: SS3447ES

Aim 1: Sampling from RCCS-experienced and RCCS-naïve households, and using the MacCAT-CR, examine adolescent capacity to consent to biomedical research and correlates of that capacity.
1.a: Compare capacity to consent among early, middle, and late adolescents and their guardians.
1.b: Assess correlates of capacity, including actionable factors such as health literacy and education and biomedical-related factors such as PrEP eligibility, use, awareness, beliefs, peer norms, and stigma.
Aim 2: Using a systematic qualitative analysis – guided by our conceptual framework for mapping age differences – examine processes of decision-making around biomedical prevention and biomedical research (e.g., stigma, understanding of biomedical prevention and research risks and benefits and constructs like randomization, privacy, safety and autonomy) among guardians and early, middle and late adolescents.
Aim 3: In partnership with US and Uganda researchers, and IRB members, construct a digital toolkit to support decision making regarding key aspects of minor consent in low-resource settings.

 Uganda 2024-11-26 19:40:05 2027-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
 Examining the combined effects of a two-generation model involving childcare and financial support interventions to vulnerable businesswomen in urban refugee and host communities in Kampala
REFNo: SS3367ES

i) To understand the status of childcare burden and its attendant constraints on livelihoods for urban refugee women.
ii) To design interventions that alleviate the childcare burden for urban refugee women while at the same time improving their social and economic welfare.
iii) To evaluate the effects of these interventions on reducing the burden of childcare as well as business growth, productivity, profitability, livelihoods, and the wellbeing of urban refugee women/caregivers.

Uganda 2024-11-25 17:30:05 2027-11-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Viral causes of acute respiratory illness among hospitalized children in Kasese District, Uganda:an observational cohort study.
REFNo: HS5218ES

Primary Objectives

The primary objective of this study is to test the feasibility of implementing rapid molecular diagnostic test and assess the burden and epidemiology of influenza subtypes A and B, SARS- CoV-2, and RSV among pediatric patients hospitalized for ARI in Kasese District, Uganda.

Specific Aims

Determine the feasibility of implementing a rapid molecular diagnostic testing program at peripheral health centers in rural western Uganda. We will measure the number of eligible children consenting to testing, the number of tests performed, the median time from sample collection to result, and the number of invalid test results due to either operator error or equipment issues.

Measure the proportion of pediatric hospitalizations for ARI attributable to SARS-CoV-2, influenza subtype A and B, and RSV in communities with different population densities in Kasese district. We will enroll children admitted with ARI, test a nasopharyngeal swab for influenza, SARS-CoV-
2 and RSV using the Cepheid GeneXpert platform, and document participant demographic information.

Describe the clinical presentation and management for patients admitted with respiratory illness to health facilities in Kasese District. We will record the vaccination history, presenting symptoms, diagnoses, and treatments administered, including antibiotics. We will also follow-up all enrolled participants two weeks after admission to determine illness outcomes. We will compare these variables between those who test positive and those who test negative for SARS-CoV-2, influenza, and RSV.

 Uganda 2024-11-25 17:28:46 2027-11-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET BABIRYE ALLEN
ID: UNCST-2023-R005641
 PREVALENCE AND ASSOCIATED FACTORS OF DYSLIPIDEMIAS AMONG PLHIV AT GOMBE HOSPITAL, IN RURAL UGANDA
REFNo: HS5050ES

ii. To determine the factors associated with dyslipidemia among PLHIV in rural Uganda.,i. To determine the prevalence of dyslipidemia among PLHIV in rural Uganda,To determine the prevalence of dyslipidemia and the associated factors among PLHIV attending the HIV clinic at Gombe hospital.,
 Uganda 2024-11-25 17:25:45 2027-11-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dorit Stein Talia
ID: UNCST-2022-R010349
 Modeling Health and Welfare Impacts of National Health Insurance in Uganda
REFNo: SS2522ES

To advance the use of routinely collected administrative data and simulation modeling for health policy decision-making in Uganda. ,To support evidence-based policy debates around what outcomes a national health insurance program should achieve, for whom, how, and at what cost. ,To quantify the distributional health and financial risk protection benefits that may occur from scaling-up a benefits package of health interventions for the most common chronic diseases in Uganda (i.e., cardiovascular diseases, cancers, diabetes).,This study aims to generate empirical evidence on the potential population health, poverty alleviation, and equity impacts of increasing public expenditure on health in the form of a national health insurance scheme in Uganda.,
 USA 2024-11-25 17:24:28 2027-11-25 Social Science and Humanities Non-Clinical Trial Degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
 Rapid Research for Diagnostics Development TB Network in children and Assessing Diagnostics at POC for TB in children (R2D2_ADAPT Kids)
REFNo: HS5144ES

1. To validate the diagnostic accuracy of design-locked novel TB tests in children with presumptive intrathoracic TB overall and in key sub-groups to inform policy development.
2. To assess the usability and acceptability of design-locked novel TB tests for children.

 Uganda 2024-11-25 17:23:03 2027-11-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rono Josea Josea
ID: UNCST-2024-R002148
 Private Sector DMPA-SE Market survey in Uganda
REFNo: SS3402ES

1. To map out the journey of WRA in accessing contraception in urban settings and identify critical touchpoints, pain points, and unmet needs.
2. To segment clients into distinct groups based on demographics, behaviours, motivations, and unmet needs and understand on how each group experiences the contraceptive journey and perceives available options.
3. To explore fit of potential DMPA-SC “concept” offerings to unmet needs from client segments and identify features, benefits, and service components that address specific pain points or desires of the target segments.
4. To explore and develop value propositions associated with each DMPA-SC “concept” offering and explore how the product concept meets the identified needs and motivations of different client segments.
5. To test the appeal, relevance, and potential effectiveness of DMPA-SC concepts. Focus on obtaining detailed feedback on value propositions, potential narratives and identify trade-offs that clients are willing to make when considering different options
6. To develop and refine DMPA-SC messaging strategies that resonate with client segments, addressing their unmet needs and supporting informed choice and self-care.

 Uganda 2024-11-25 16:25:42 2027-11-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patience Kinengyere Bemanya
ID: UNCST-2024-R004964
 Evaluation of Diabetic Retinopathy Detection Strategies in Urban Kampala, Uganda
REFNo: HS5046ES

To assess WHO DR detection protocols and facilitate the adoption of a customised early DR detection strategy among DM patients in Urban Kampala, Uganda, to enhance management outcomes,
 Uganda 2024-11-25 14:19:24 2027-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okot Pakono
ID: UNCST-2019-R000417
 Change Management Framework for Information and Communication Technology Integration in Teaching and Learning in Uganda: A Case of Gulu University
REFNo: SS3361ES

Objectives
1)To explore the process constituting the SC eLIM in the PBL–Hybrid Learning Project at FBDS in GU.
2)To explore how the activities within the PBL–Hybrid learning project unfold at FBDS in GU.
3)To explore how the PBL–Hybrid project’s SC eLIM changes the learning environment at FBDS in GU.
4)To develop a change management framework for systematic ICT integration in teaching and learning in universities in resource–constrained settings.

 Uganda 2024-11-25 13:28:05 2027-11-25 Social Science and Humanities Non-Clinical Trial Degree Award
Okwarampe  Millicent
ID: UNCST-2024-R002469
 Teachers Mentoring Teachers - An Exploration into Effective Peer Support Models & Their Impact
REFNo: SS3386ES

To assess the effectiveness of self-initiated peer mentoring systems
in supporting teachers with their UCatchUp implementation in government and government-aided
primary schools

Uganda 2024-11-25 13:27:02 2027-11-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Immaculate  Nakazibwe
ID: UNCST-2023-R006394
 Agronomic Status of Finger Millet Production Amidst Climate Variability and its Yield Response to Different Soil Fertility Treatments in South Western Uganda
REFNo: A535ES

Map land suitability for sustainable finger millet production in South western Uganda,Predict the finger millet grain yield using the QUEFTS model for the varying soil fertility treatments at varying spatial and temporal scales,Determine the nutrient use efficiency of finger millet under differing soil fertility treatments at varying spatial and temporal scales,Explore and establish farmers’ knowledge, attitudes and practices for finger millet production within and across agricultural production zones,Assess the agronomic status of finger millet production amidst climate variability and its yield response to different soil fertility treatments in South western Uganda,
 Uganda 2024-11-25 13:25:39 2027-11-25 Agricultural Sciences Non-Clinical Trial Degree Award
Marisa Boller
ID: UNCST-2023-R005654
 Development and validation of a tool to measure experiences of water, sanitation, and hygiene insecurity in institutional settings
REFNo: SIR300ES

To develop a tool that can measure WASH insecurity levels within institutions by identifying a set of items that comparably and reliably measure WASH insecurity within schools and health care facilities across different settings, climates, and participant characteristics.
 Switzerland 2024-11-25 13:24:06 2027-11-25 Engineering and Technology Non-Clinical Trial Non-degree Award
Jane Nabikyu Rosette
ID: UNCST-2024-R002380
 Consumer preference for novel and nutritious black rice in Wakiso district, Uganda: information, willingness to pay and affordability
REFNo: SS3279ES

Determine the cost and affordability of an optimal black rice-based diet in Wakiso District.,Determine the effect of nutrition information on consumers’ willingness-to-pay for black rice in Wakiso District.,Determine consumer acceptance of black rice in Wakiso District.,To examine consumer demand for and affordability of black rice in Wakiso District, Uganda.,
 Uganda 2024-11-22 17:35:05 2027-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
MONICA AHABWE
ID: UNCST-2023-R006462
 Teachers' experiences in Implementing the Lower Secondary Curriculum in Mbarara City in Uganda
REFNo: SS2973ES

1. To examine secondary school teachers’ experiences of planning for teaching using the Lower Secondary Curriculum in Mbarara City in Uganda?
2.To examine secondary school teachers’ experiences of teaching using the Lower Secondary Curriculum in Mbarara City in Uganda?
3. To examine secondary school teachers’ experiences of assessment using the Lower Secondary Curriculum in Mbarara City in Uganda?

Uganda 2024-11-22 17:28:45 2027-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
John Tabuti Robert Stephen
ID: UNCST-2024-R002181
 Agroforestry for People, Ecosystems and Climate (AfPEC)
REFNo: NS818ES

AfPEC aims to document the effects of agroforestry in terms of ecosystem services and livelihood benefits, to understand motivating factors for long-term sustainable development and to support science-based agroforestry in practice.
 Uganda 2024-11-22 17:26:03 2027-11-22 Natural Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 mAb Therapeutics for Sudan ebolavirus: Discovery, Isolation, and Target-Epitope Mapping of Monoclonal Antibodies from Sudan ebolavirus Convalescent Survivors in Uganda (mATSu)
REFNo: HS5212ES

This study aims to improve understanding and enhance the development of potent immune-based tools for detection, treatment, and vaccination strategies, strengthening readiness for future Viral Hemorrhagic Fever (VHF) epidemics. It will address five specific objectives:

Objective 1: Collect, process and screen samples from Viral Hemorrhagic Fever (VHF) survivor acute and convalescent cases along with their close contacts.

Objective 2: Isolate and characterise functionalities of the monoclonal antibodies.

Objective 3: Establish partnerships to facilitate transfer advanced technologies.

Objective 4: Build local capacity for immune therapies.

Objective 5: Describe molecular determinants underpinning the presence or lack of potent mAbs.
 Uganda 2024-11-22 17:23:36 2027-11-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 Open-label, Multicenter Immunogenicity and Safety Trial of MVA-BN® Vaccine in Children From 2 Years to Less Than 12 Years of Age Compared to Adults for the Prevention of Smallpox, Mpox, and Related Orthopoxvirus Infections
REFNo: HS5281ES

To assess immunogenicity of the MVA-BN standard regimen in eliciting neutralizing antibodies against vaccinia virus in children compared to adults. To assess the safety and reactogenicity of the MVA-BN standard regimen in children and adults. To assess neutralizing antibody response to the MVA-BN standard regimen. To assess durability of neutralizing antibody response to the MVA-BN standard regimen.
Uganda 2024-11-22 17:19:29 2027-11-22 Medical and Health Sciences Clinical Trial Non-degree Award
Florence  Ebila
ID: UNCST-2021-R013444
 TASO-2024-401 Beyond Gendered textbooks: An investigation into gender(ed) discourses in secondary English language classrooms in India and Uganda.
REFNo: SS3317ES

3.To analyse the extent to which engaging teachers with gendered classroom practices and learners’ gendered experiences shape their reflections the development of gender responsive pedagogies.,2. To assess how the gendered discourses in the EL classroom influence male and female students’ learning. experiences, self-perception and aspirations,1. To find out how teachers and students engage with gendered texts in the EL classroom.,The aim of this study is to investigate how gender is (co-)constructed in secondary school English language (EL) classrooms in India and Uganda with the view of identifying patterns which would inform gender responsive English language teaching and teacher education.,
 Uganda 2024-11-19 7:35:59 2027-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Needs and Experiences of Transgender Women Using Gender-Affirming Hormone Therapy in Uganda: A Mixed Methods Study
REFNo: HS5137ES

Aim 1: Assessment of needs and experiences to determine gaps in access to gender-affirming treatment in Uganda Aim 2: Use photovoice methods to gain a better understanding of the real-world healthcare experiences of trans women in Uganda
Uganda 2024-11-19 7:34:06 2027-11-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benson Juma Ouma
ID: UNCST-2023-R005718
 ESTABLISHMENT AND EVALUATION OF NON-INVASIVE WHITE CELL MONITORING (NICEM) IN UGANDA
REFNo: HS5245ES

To compare the total white blood counts and differential white blood cell subtypes obtained by the Non-Invasive White Cell Monitoring prototype with conventional CBC testing using vein puncture in healthy volunteers,
 Uganda 2024-11-19 7:32:44 2027-11-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Natalie Carter Lauren
ID: UNCST-2023-R005867
 Existing in the periphery: narrating gendered dynamics of conservation in Karamoja, northern Uganda
REFNo: SS3258ES

The objectives of this research are as follows: • To map the position of community members in a conservation corridor by narrating their relationship to land and the environment, exploring how their daily lives may shape the production of the corridor space from within • To explore how a conservation corridor shapes the lives and relationships of community members, with particular attention to expanding an understanding of the relationship between connectivity conservation and intersecting experiences of violence (i.e., human-wildlife/human conflict) • To constructively challenge emergent scientific narratives about connectivity conservation by mapping friction between territorial claims for biodiversity conservation in the abstract against the unruly practices within a corridor • Applied aim: To translate shared narratives into formats and fora which could influence the ethical and just transformation of connectivity conservation practice
 Australia 2024-11-19 7:31:10 2027-11-19 Social Science and Humanities Non-Clinical Trial Degree Award
NAKAJUBI SHAMUSI
ID: UNCST-2024-R003579
 “BLOCKCHAIN-BASED FRAMEWORK FOR INTRA-DATA SHARING IN SAVINGS AND CREDIT COOPERATIVE SOCIETIES (SACCOS)” A CASE OF WAZALENDO SACCO - UGANDA
REFNo: SIR412ES

To Evaluate the framework for intra-data sharing in SACCOS.,To develop a Blockchain-based Framework for intra-data sharing in SACCOS.,To examine the challenges faced in the current intra-data sharing processes in SACCOS,To establish the current state of the art and Intra-data sharing practices in SACCOS,The general objective of this study will be to develop a Blockchain-based Framework for intra-data sharing in SACCOS. ,
 Uganda 2024-11-19 7:28:29 2027-11-19 Engineering and Technology Non-Clinical Trial Degree Award
EBENEZER DEBRAH LARTEY
ID: UNCST-2023-R007570
 Artificial Intelligence-Based Enhancement of Mammography Interpretation for Early Breast Cancer Diagnosis
REFNo: SIR368ES

d. To evaluate the acceptability and usability of the developed model.,c. To test and validate the developed algorithms for accurate and timely diagnosis and classification of breast cancer from x-ray mammograms.,b. To develop AI-based algorithms for accurate and timely diagnosis and classification of breast cancer from x-ray mammograms.,a. To establish the extent to which artificial intelligence has been adopted in breast cancer diagnosis and classification from x-ray mammograms.,The main objective is to improve the accuracy and timely diagnosis of breast cancer from X-ray mammograms in resource-constrained areas.,
 Ghana 2024-11-19 7:25:26 2027-11-19 Engineering and Technology Non-Clinical Trial Degree Award
Sam Ononge
ID: UNCST-2020-R000328
 Evaluating utilization of VAYU Bubble Continuous Positive Airway Pressure (CPAP) device piloted among health facilities participating in Saving Women and Preterm Babies (SWAP) Project in Uganda: Ref UNHL-2024-91
REFNo: HS5148ES

To determine the acceptability, feasibility, and sustainability of the Vayu bCPAP among healthcare providers in the five SWAP project-supported facilities as part of the routine care for newborns with respiratory distress, primarily preterm newborns. ,4. To draw recommendations for the scale-up to other facilities in Uganda, 3. To explore the sustainability of Vayu bCPAP in health facilities in Uganda ,2. To determine the key factors that facilitate or hinder the successful implementation of Vayu bCPAP,1. To assess health providers\' acceptability and feasibility of Vayu bCPAP in selected health facilities in Uganda ,To determine the acceptability, feasibility, and sustainability of the Vayu bCPAP among healthcare providers in the five SWAP project-supported facilities as part of the routine care for newborns with respiratory distress, primarily preterm newborns. ,
 Uganda 2024-11-19 7:24:21 2027-11-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssinabulya
ID: UNCST-2021-R004352
 ImpleMEntation of a Digital-first care deLiverY model for heart failure in Uganda (MEDLY Uganda)
REFNo: HS4581ES

In this study, we will implement a digital-first, multi-component strategy for HF (Medly Uganda) and evaluate both implementation and clinical outcomes. The primary objective is to assess the implementation and clinical effectiveness of a digital-first implementation strategy to improve HF self-care in Uganda. We will conduct a stepped-wedge, cluster randomized trial in outpatient departments at 6 Ugandan RRH. The co-primary outcomes will be the Self-Care of HF Index (implementation) and the composite of mortality and HF hospitalization (clinical effectiveness). The secondary objectives will include the following. Conduct a mixed method process evaluation to inform iterative adjustments to the implementation process. We will use a community-engaged approach to systematically collect qualitative and quantitative process data at pre-determined time points based on the Learn-As-You-Go design and make contextually appropriate implementation adaptations. Prior to recruitment, we will also explore patients’ journeys to heart failure diagnosis in Uganda through a qualitative component by conducting in-depth interviews. The aims of this work will be to explore factors associated with patient’s journeys to heart failure diagnosis, including descriptions of initial symptoms, progression, health care referral journey, barriers and facilitators to care, and role of health education and self-care awareness. We will assess the implementation fidelity and sustainability of Medly Uganda with a focus on reach, adoption, and maintenance. Using Medly Uganda meta data from patients (app) and providers (dashboard), we will identify patterns and predictors of usage. We will interview patients and providers to explore these findings, and ensure implementation fidelity. We will also explore patient and provider perspectives on the sustainability of Medly Uganda, using semi-structured interviews to explore patient and provider barriers and facilitators of long-term use, to surface strategies that would optimize Medly Uganda implementation over time. We shall explore cost, cost effectiveness, and sustainability factors for Medly Uganda. We will collect and examine cost data from patients and facilities examining the unit cost (cost per HF patient treated and per HF patient controlled) of control and Medly Uganda scenarios both from a financial and societal perspective. Primary outcomes for cost effectiveness analysis will be the Incremental Cost-Effectiveness Ratio per patient treated and per death averted.
Uganda 2024-11-18 22:56:37 2027-11-18 Medical and Health Sciences Clinical Trial Non-degree Award
MUTEEBWA LABAN
ID: UNCST-2022-R010550
 Barriers and facilitators of the intention to use, and the preferred model for HIV Self-Testing among young women in the Kampala Metropolitan Area
REFNo: HS5167ES

4. To assess factors associated with the intention to use HIVST services among AGYW in KMA.,3. To determine the preferred model for delivering HIVST services among AGYW in KMA.,2. To explore the barriers and facilitators influencing the use of HIVST services among AGYW in KMA,1. To determine the level of intention to use HIVST services among AGYW in KMA ,To determine the level of intention to use HIVST services, the influencing barriers and facilitators, associated factors and the preferred model for delivering HIVST services among AGYW in the KMA, Uganda.,
 Uganda 2024-11-18 22:50:43 2027-11-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Secondary Analysis Protocol entitled “Biomarker-guided patient stratification for diagnosis, prognosis, and monitoring of severe infectious disease at the point of need"
REFNo: HS5187ES

Transition existing host-based biomarker classifiers to protein and nucleic acid based fieldable detection devices to validate and optimize performance
 Uganda 2024-11-18 22:47:28 2027-11-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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