Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ritah Ayebazibwe
ID: UNCST-2025-R018248
 Prevalence and determinants of subclinical myocardial injury among people living with HIV and diabetes at the ISS clinic, Mbarara Regional Referral Hospital
REFNo: HS7521ES

1.To determine the prevalence of subclinical myocardial injury among people living with HIV and DM at ISS Clinic.

2.To determine the factors associated with subclinical myocardial injury among people living with HIV and diabetes at ISS Clinic.

3.To determine the correlation between glycemic control and Cardiac infarction Injury Score (CIIS) among PLWH and DM at ISS Clinic.

 Uganda 2026-07-14 9:43:33 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Immaculate Tumwebaze
ID:
The Impact of Climate Change on a Major Host-Parasite System (Bulinus-Schistosoma) across ecological gradients-disentangling global environmental changes and other factors
REFNo: NS1209ES

The proposed study will address three overarching questions:
1. How do intrinsic (genetics, hybridization, polyploidy) and extrinsic (climate, habitat) factors shape Bulinus diversity and host competence?
2. What are the evolutionary and ecological mechanisms underlying host-parasite adaptation in extreme environments?
3. How will climate-driven changes affect disease risk and transmission patterns across Africa and beyond?

 Uganda 2026-07-14 9:41:38 2029-07-14 Natural Sciences Non-Clinical Trial Non-degree Award
Boaz Turyahikayo
ID: UNCST-2026-R024695
 FACTORS AND BARRIERS TO MEASLES RUBELLA 2 UPTAKE AMONG CAREGIVERS OF CHILDREN 20-36 MONTHS IN ISINGIRO DISTRICT.
REFNo: HS8031ES

1. To estimate the prevalence of Measles Rubella 2 (MR2) vaccine uptake among children aged 20–36 months in Isingiro District. 2. To determine the association between caregiver knowledge, attitudes, accessibility to immunization services, trust in health services, socio-demographic characteristics, and uptake of MR2 vaccine among children aged 20–36 months in Isingiro District. 3. To explore caregiver, community, and health-system barriers influencing uptake of the Measles-Rubella 2 (MR2) vaccine among children aged 20–36 months in Isingiro District
Uganda 2026-07-14 9:40:16 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Anacret Byamukama
ID: UNCST-2023-R007193
 Prevalence and correlates of pulmonary hypertension among people with HIV in Uganda
REFNo: HS7889ES

Aim 1: To characterize the prevalence and clinical correlates of pulmonary hypertension among people with HIV compared to those without HIV in Uganda. Aim 2: To evaluate the relationship between biomarkers of inflammation and endothelial dysfunction by HIV serostatus and assess whether these biomarkers correlate with pHTN in Uganda.
Uganda 2026-07-14 10:26:03 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAMUEL JJUNJU
ID: UNCST-2023-R006269
 Pneumocystis Pneumonia Among Adults with Advanced HIV Disease Diagnosed with Pulmonary Syndrome In South Western Uganda. A Prospective Observational Cohort Study
REFNo: HS7796ES

I.To determine the prevalence of Pneumocystis pneumonia among adults with advanced HIV disease presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. II.To evaluate the diagnostic performance of serum ?-D-glucan and oropharyngeal PCR for detection of Pneumocystis jirovecii among adults with advanced HIV disease presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. III.To determine the in-hospital outcomes among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. IV.To determine the 30-day post hospital discharge mortality among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. V.To determine the baseline predictors of mortality among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital.
 Uganda 2026-07-14 10:21:26 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Passy Claire Wood
ID: UNCST-2025-R023226
 Social Protection Programming and Refugee Girls' Transition to Secondary Education in Uganda: Barriers and Opportunities.
REFNo: SS5423ES

1.To understand the day-to-day experiences of refugee girls during the transition from Primary school to secondary school. 2.To examine what household and community support is available to these refugee girls and how they experience its adequacy during the transition from primary to secondary school. 3.To analyse the perceptions of these refugee girls on their family’s use of cash transfers in supporting their school needs. 4.To explore what forms of support these refugee girls consider necessary for successful and safe transitions from primary to secondary school.
 Uganda 2026-07-14 10:16:18 2029-07-14 Social Science and Humanities Non-Clinical Trial Degree Award
Marianna Agaba Nyangire
ID:
Work-Related Musculoskeletal Disorder prevention among manufacturing workers in Kampala Industrial Park and Business Park, Namanve-Uganda: prevalence, safe practices, and the effect of participatory toolbox talks
REFNo: HS7589ES

Overall aim
To assess the prevalence and factors associated with Work-Related Musculoskeletal Disorders (WRMSDs), identify participatory toolbox talk components, and evaluate their effectiveness among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.
4.2.2 Sub-studies
1. To estimate the prevalence of Work-Related Musculoskeletal Disorders (WRMSDs) and determine their associated factors among manufacturing workers within Kampala Industrial and Business Park, Namanve-Uganda.
2. To explore factors influencing safety practices related to WRMSDs of manufacturing workers within Kampala Industrial and Business Park, Namanve, Uganda.
3. To identify contextually appropriate components and delivery strategies for participatory toolbox talks that prevent WRMSDs among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.
4. To evaluate the effect of participatory toolbox talks on the occurrence of WRMSDs among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.

 Uganda 2026-07-14 10:12:12 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Johnes Obungoloch
ID: UNCST-2024-R005331
 Evaluation of the Functionality of the Lab-Built Halbach Array MRI System at Mbarara University of Science and Technology
REFNo: HS8105ES

The overall aim of this study is to benchmark the image quality of the open-source low-field MRI system constructed at the MRI-Uganda lab of MUST1 with the identical system constructed at the LUMC.

specific Objectives

i.To acquire T1 and T2 weighted limb and brain images of adult volunteers using the low-field MRI system at the MUST lab, and the 1.5T MRI at Mbarara Regional Referral Hospital.

ii.To evaluate signal-to-noise ratio (SNR), contrast to noise ratio (CNR), image resolution, and accuracy of the anatomical structures shown.
 Uganda 2026-07-14 10:01:45 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
 Substance Use and Harm Reduction Needs among Urban Refugees in Kampala, Uganda
REFNo: HS7826ES

The objective of the proposed research is to explore substance use among refugees in Kampala and their access to drug treatment and harm reduction services.
Specific objectives
Specific objectives of the proposed research are:
1. To explore patterns of substance use among refugees in Kampala including kinds of substances used, reasons for use and the social, legal and health consequences of substance use. (Questions 1-3)
2. To explore the services available to refugees to stop or reduce substance use or harms associated with substance use. (Questions 4 and 5).


 USA 2026-07-13 18:43:13 2029-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FAITH  AHABYOONA MUGISHA
ID: UNCST-2025-R019772
 Effect of Climate-Smart Financing on Market-Driven Coffee Production in Uganda
REFNo: SS4866ES

General Objective: To examine the effect of climate-smart financing on market-driven coffee production in Uganda. Specific Objectives: 1. To assess the effect of financing coffee nurseries on market-driven coffee production. 2. To investigate the effect of farm rejuvenation financing on market-driven coffee production. 3. To examine the effect of financing Coffee Washing Stations on coffee competitiveness and quality.
Uganda 2026-07-13 18:37:25 2029-07-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ying Su
ID: UNCST-2026-R024567
 Experiences of Lay Counsellors in Addressing Stigma During Group Support Psychotherapy and Its Relationship with Suicidal Behaviour among Depressed Persons Living with HIV in Uganda: A Mixed Methods Study
REFNo: HS7630ES

To address these gaps, this study adopts a mixed-methods, mechanism
focused design that integrates qualitative insights from lay counsellors
with secondary quantitative analysis of trial data.
Specifically, the study aims to:
i)
Explore how lay counsellors working in community settings in
Uganda understand, experience, and address stigma among their
clients, and to identify the psychosocial, relational, and practical
mechanisms through which their support facilitates coping,
engagement in care, and recovery.
ii)
iii)
Examine the baseline association between HIV-related stigma
and suicidality—operationalised as suicidal ideation and history
of previous suicide attempt—among depressed people living with
HIV.
Determine whether Group Support Psychotherapy reduces
suicidal ideation over time, particularly at 2 months (during
therapy) and 6 months (post-therapy), compared with the control
condition.
 China 2026-07-13 11:34:56 2029-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dorcas Adongo
ID: UNCST-2025-R023015
 FACTORS ASSOCIATED WITH ACCESSIBILITY OF FAMILY PLANNING SERVICES AMONG PERSONS WITH DISABILITIES IN LIRA CITY
REFNo: SS4906ES

General objective To examine the factors associated with accessibility of family planning services among persons with disabilities in Lira City. Specific Objectives 1.To assess the level of access to family planning services among PWDs. 2.To assess the sociodemographic factors associated with the level of accessibility of family planning services among PWDs. 3.To investigate disability-related factors associated with accessibility of family planning services. 4.To explore health system factors associated with accessibility of family planning services among PWDs.
Uganda 2026-07-13 11:30:01 2029-07-13 Social Science and Humanities Non-Clinical Trial Degree Award
Fred  Okuku Machyo
ID:
EVALUATING THE INTEGRATION OF PEGFILGRASTIM FOR THE MANAGEMENT OF CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS8034ES

1. To assess the feasibility and uptake of pegfilgrastim prophylaxis among eligible adult chemotherapy patients at UCI, including reach, fidelity, and vial utilization patterns.
2. To compare clinical outcomes, specifically FN incidence, infection-related hospitalizations, and chemotherapy dose delays or reductions, between pegfilgrastim recipients and historical cohorts managed without routine G-CSF prophylaxis.
3. To document baseline filgrastim prescribing patterns, dosing practices, and associated clinical outcomes prior to pegfilgrastim integration.
4. To evaluate healthcare workers’ knowledge, attitudes, and perceptions regarding FN prevention and the comparative use of pegfilgrastim versus filgrastim.
5. To identify system-level, provider-level, and process-level barriers and facilitators influencing pegfilgrastim implementation and long-term sustainability within UCI.

 Uganda 2026-07-09 19:40:59 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joan Busingye
ID: UNCST-2026-R026289
 COGNITIVE BEHAVIORAL INTERVENTIONS AND PATIENT RECOVERY AMONG INDIVIDUALS WITH MENTAL ILLNESS. A CASE OF SELECTED HOSPITALS IN CENTRAL UGANDA
REFNo: SS5507ES

1. To determine the influence of cognitive interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
2. To assess the effect of emotional interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
3. To examine the influence of behavioral interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
4. To evaluate the moderating effect of patient-related factors (age, gender, diagnosis, duration of illness, treatment adherence, and cultural beliefs) on the relationship between cognitive behavioral interventions and patient recovery in selected hospitals in Central Uganda.

 Uganda 2026-07-09 19:38:45 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Development of a Rapid Fieldable Nanopore Sequencing-based Prognostic and Diagnostic Assay to Advance Clinical Management Decision-Making
REFNo: HS7987ES

- Verify harmonized sample preparation workflow from archived biospecimens for the integrated pathogen diagnostic and host-response assay that is run on the INSPIRE device - Verify functionality of integrated software and hardware required for the INSPIRE device on archived biospecimens
Uganda 2026-07-09 19:37:11 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick ALUKU
ID: UNCST-2026-R025007
 DETERMINANTS OF MARKET ACCESS FOR SMALLHOLDER HORTICULTURE FARMERS IN MBALE DISTRICT: A CASE STUDY OF ONION AND CARROT PRODUCERS IN WANALE SUB-COUNTY...
REFNo: A803ES

This study aims to examine the determinants of market access for smallholder horticulture farmers in Mbale district: a case study of onion and carrot producers in Wanale Sub-County. Specific objectives: The study aims to achieve the following objectives: 1. To assess the effect of market infrastructure on market access for smallholder horticulture farmers in Wanale Sub-county. 2. To examine the effect of institutional support on market access for smallholder horticulture farmers in Wanale Sub-county. 3. To determine the effect of transaction costs on market access for smallholder horticulture farmers in Wanale Sub-county. 4. To find out the other factors affecting market access for smallholder horticulture farmers in Wanale Sub-county.
 Uganda 2026-07-09 19:36:00 2029-07-09 Agricultural Sciences Non-Clinical Trial Degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to Monitor Grey Crowned Cranes in Uganda through Colour Band Ringing and Aerial Surveys
REFNo: NS1291ES

1. To establish a standardized crane ringing program by fitting ELSA colour rings on 20 Grey Crowned Crane chicks annually over a five-year period.
2. To track and document movement patterns and habitat use of colour-marked cranes across breeding, foraging, and dispersal landscapes.
3. To estimate survival rates and recruitment of juvenile cranes through periodic resighting of marked individuals.
4. To generate baseline biological and ecological data (including morphometrics) to address key knowledge gaps in the species’ life cycle.
5. To strengthen evidence-based conservation planning and adaptive management for Grey Crowned Crane populations in Uganda.
6. Provide data on Grey Crowned Crane populations and their distribution in Uganda
7. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
8. Identify areas where the potential exists for crane conservation interventions


Uganda 2026-07-09 19:34:31 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
muyunga ashiraf
ID: UNCST-2025-R021888
 CUSTOMARY LAND DISPUTES ADJUDICATION AND TENURE SECURITY IN UGANDA: A CASE STUDY OF ACHOLI SUB REGION
REFNo: SS5467ES

a)To examine the legal and institutional framework governing customary land tenure adjudication in Uganda and its applicability to the Acholi context. b) To examine the jurisprudential approaches and evidentiary standards adopted by superior courts in the adjudication of customary land disputes in the Acholi sub-region. c) To assess the impact of formal judicial outcomes on tenure security within the plural adjudicatory context of the Acholi sub-region d) To propose legal and institutional reforms for strengthening the adjudication of customary land disputes and tenure security based on findings from the Acholi subregion.
 Uganda 2026-07-09 19:33:37 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Bashemera Birungi Brenda
ID: UNCST-2025-R021775
 A Deep Learning Framework for Stroke Biomarker Detection and Prediction of Post Stroke Epilepsy in Brain CT Scans
REFNo: SIR712ES

1.Collect and curate brain CT scan image datasets. 2. Develop a deep learning segmentation model to detect stroke biomark- ers. 3. Develop a deep learning prediction model to predict the likelihood of Post Stroke Epilepsy (PSE) to a high degree of accuracy. 4. Develop Large Language Models (LLM) to provide clinical reports from the deep learning models for stroke segmentation and post-stroke epilepsy prediction.
 Uganda 2026-07-09 19:30:44 2029-07-09 Engineering and Technology Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 POPULATION-BASED EVALUATION OF THE EPIDEMIOLOGY OF NON-COMMUNICABLE DISEASES AND SOCIOCULTURAL CONTEXT AMONG ADULTS OF TWO RURAL POPULATIONS IN UGANDA.
REFNo: HS7934ES

To build a cohort platform of adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda, with linkage to routinely collected clinical and/or medico-administrative data at the health centre to answer pertinent research questions about NCDs. ,To determine the trends in prevalence and incidence of Diabetes Mellitus and Hypertension among the cohort participants in among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,To document the sociocultural determinants of health to inform the development of community-led strategies for health promotion and improved quality of life among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda. ,To determine the burden of known risk factors such as obesity, lifestyle, smoking and diet, associated with Diabetes Mellitus and Hypertension among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,.To determine the prevalence of Diabetes Mellitus and Hypertension and examine associated sociocultural factors among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,
 Uganda 2026-07-09 19:26:55 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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