Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Catherine Abaasa N
ID:
ASSESSING RIFT VALLEY FEVER PREVENTION AND CONTROL PREPAREDNESS AND REPORTING DYNAMICS: A CASE OF KASHARI COUNTY MBARARA, UGANDA
REFNo: NS797ES

This study aims at assessing the preparedness level of Kashari County to effectively respond to a potential Rift Valley Fever (RVF) outbreak and to identify and analyze the barriers and facilitators influencing the reporting of RVF signals among various stakeholders in Kashari County, Mbarara district ,I. To assess the preparedness level of Kashari County to effectively respond to a potential Rift Valley Fever (RVF) outbreak. II. To identify and analyze the barriers and facilitators influencing the reporting of RVF signals among various stakeholders within Kashari County,
Uganda 2025-11-13 16:48:09 2028-11-13 Natural Sciences Non-Clinical Trial Non-degree Award
Kazunari Ushida
ID:
Conservation science of African Grey Parrot
REFNo: NS744ES

African Grey Parrot is endangered bird species. Their physiological and genetic characteristics must be known for the better conservation. As Chubu University and UWEC start the joint conservation project for African Grey Parrot with the finance from Japanese goverment (Japan International Cooperation Agency, JICA). We focus on the role of zoo in the ex-situ African Grey Parrot conservation in which development of the nutrition science, the breeding science, the behavior science, and the veterinary science toward this particular species are essential for the future success of ex-situ conservation.
Japan 2025-11-13 16:46:55 2028-11-13 Natural Sciences Non-Clinical Trial Non-degree Award
Ali Waiswa
ID: UNCST-2025-R020882
ARTIFICIAL INTELLIGENCE AND DEEP LEARNING BASED IRIDOLOGY FOR DETECTION OF COLORECTAL CANCER
REFNo: HS6756ES

To determine the sensitivity of AI and deep learning based iridology for detection of colorectal cancer in Uganda over a period of one year.
To determine the specificity of AI and deep learning based iridology for detection of colorectal cancer in Uganda over a period of one year.

Uganda 2025-11-13 16:40:17 2028-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HAKIIMU KAWALYA
ID: UNCST-2025-R020311
Sickle Cell Modifier Genes Across Diverse Human Populations
REFNo: HS6710ES

1) To profile the most common fetal hemoglobin associated sickle cell disease modifier genes 2) To determine population specific gene expression patterns of fetal hemoglobin associated sickle cell disease modifier genes 3) To characterize inter-population Allele Frequencies of fetal hemoglobin associated sickle cell disease modifier gene variants 4) To analyze selection signals in fetal hemoglobin associated sickle cell modifier genes using human whole genome sequencing data
Uganda 2025-11-13 15:27:46 2028-11-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Partial Analytical and Clinical Performance Study focusing on Specimen Type Equivalence, Diagnostic Sensitivity and Specificity, and Usability Evaluation of ConfiSign HCV Pro.
REFNo: HS6742ES

3. Qualification of usability for professional use of ConfiSign HCV Pro through a label comprehension study and a results interpretation study which are to be completed by at least 3 laboratory professionals and at least 4 lay providers/healthcare workers.,2. Establish part of the clinical performance (diagnostic sensitivity and specificity) of ConfiSign HCV Pro using capillary whole blood samples.,1. Demonstrate the specimen type equivalence between capillary whole blood, venous whole blood, serum and plasma samples while using ConfiSign HCV Pro.,The general objective of this study is the partial evaluation of both clinical and analytical performance as well as qualification of usability for professional use of the ConfiSign HCV Pro according to parts of WHO TSS-16 (Part 1 - section 1.2.1, Part 2a - sections 2a.1.1 to 2a.1.3, Part 3a - sections 3a.1.1 to 3a.1.2) and CS (Annex I - Part I and Part II and Annex V - Table 2). For further details, see section 7.4.,
Uganda 2025-11-07 5:14:01 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Caroline Gotsche Isabelle
ID: UNCST-2025-R021504
Antenatal syphilis testing in central Uganda - Exploring provider-level factors affecting maternal syphilis testing coverage
REFNo: HS6671ES

1. Mapping the current body of literature of syphilis testing in ANC services.This will allow us to obtain an overview on the current state of syphilis testing among pregnant women in ANC services in Uganda. 2. Understanding impeding and facilitating factors of syphilis testing in ANC services. Investigating providers` (Health Care Workers (HCW), midwives, nurses and physicians) knowledge of syphilis, and their experiences, perceptions, ideas and interest in syphilis testing will be essential to gain deeper understanding of these factors. Additionally, providers’ interest and ideas on engaging partners in antenatal syphilis testing will be explored to address the issue of re-infection in pregnant women. To gain an overview of a pregnant woman’s journey through the clinic, paying particular attention to how syphilis screening fits into antenatal care clinic observations will be conducted. 3. Exploring syphilis self-testing as a novel syphilis testing strategy in ANC services.
Investigating policy makers`, providers’ and pregnant women’s understanding and interest in the use of syphilis self-testing will be investigated. Whether the use of secondary distribution of self-test kits to partners of pregnant women to enhance partner engagement may be an acceptable approach among pregnant women will be also examined.
Germany 2025-11-07 5:12:16 2028-11-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
Promoting education and child well-being through the Education for Protection and Well-being model in Sironko and Budaka districts, Uganda: A cluster non-randomised controlled trial (EPW – Study)
REFNo: HS6277ES

4.1 General Objective
The purpose of this study is to assess the effectiveness of the EPW Program on children, caregivers, and teachers.
4.2 Specific Objectives
1. To assess the effectiveness of the EPW program by comparing intervention and control schools in terms of Student social-emotional learning (SEL) practices, Caregiver-child relationships and positive parenting practices and Teachers’ positive classroom management practices
2. To assess the prevalence of secondary outcomes for each participant group
3. To determine implementation factors (e.g., attendance, fidelity) that influence program effectiveness.
4. To establish the level of satisfaction, barriers and facilitators to participation in the program up to endline in intervention group.
Uganda 2025-11-07 5:10:34 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Caroline Agabiirwe Noel
ID: UNCST-2025-R020394
Development and effectiveness of the Better Health media campaign on maternal and child health-seeking behaviours in Uganda.
REFNo: HS6737ES

1. To explore the knowledge, attitudes, and practices among the target audiences related to ANC, PNC, malaria vaccine and diarrhoea management in children. 2. Assess the acceptability of the campaign among the target audience, exploring attitudes of the target audience towards the campaign and mechanisms of campaign impact. 3. Run a controlled quantitative evaluation study to assess the impact of the campaign on knowledge, beliefs, intentions and behaviours related to ANC, PNC and malaria vaccine. 4. To complement the quantitative study with controlled time series analysis of routine DHIS2 data, to examine shifts in trends in treatment seeking, ANC uptake, PNC uptake, and malaria vaccine uptake that may be attributable to the campaign.
Uganda 2025-11-07 5:08:21 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
VICTORIA NYAITEERA
ID: UNCST-2021-R011699
Knowledge, attitudes, practices, and moderators of Competency Based Medical Education: A needs assessment and faculty development in CBME delivery at Mbarara University of Science and Technology
REFNo: HS4973ES

5. To suggest appropriate adjustments to curricula implementation process for fidelity improvement.,4. To determine the moderators (facilitators and barriers) of competency based medical training in post graduate programs,3. To train the faculty involved in postgraduate medical training on CBME implementation.,2. To identify MUST FOM faculty development/training needs for successful CBME implementation.,1. To assess the knowledge attitudes and practices of faculty towards competency-based training in medical post graduate programs at MUST,To improve the fidelity of competency based medical training curricula for postgraduates at MUST by training the faculty in CBME delivery and making faculty training in CBME a MUST institutional priority.,
Uganda 2025-11-07 5:06:17 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Igaga Namugaya
ID: UNCST-2022-R011354
Advancing Health and Leadership: A Wellbeing Toolkit for Women in Anesthesia and Surgery in Uganda
REFNo: HS6633ES

General Objective To determine the state of wellbeing among the women in the Anesthesia and Surgical Specialties in Uganda Specific Objectives To understand how women in the Anesthesia and Surgical Specialties in Uganda define wellbeing. To determine the state of well-being among women in the Anesthesia and Surgical Specialties in Uganda.
Uganda 2025-11-07 5:05:10 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NANCY MITAKI Bonareri
ID: UNCST-2024-R003431
Biochemical Studies and Anti-diabetic mechanism of Cucurbita maxima Duchesne (Pumpkin) fruit extracts in diabetic Rats
REFNo: NS970ES

6. Determine the stability, structure’s function, and behavior of the bioactive compounds from the most active fraction of C. maxima and the target proteins,5. Predict interactions between active compounds (ligands) and diabetic target proteins such as Fibroblast growth factor 21 (FGF21), alpha-amylase and alpha-glucosidase.,4. Identify the bioactive components in the most active fraction of C. maxima fruits.,3. Determine the effects of fractions of C. maxima fruit on oxidative stress markers (Superoxide dismutase, Catalase, Glutathione peroxidase, and malondialdehyde) in diabetic rats.,2. Evaluate the effects of fractions of C. maxima fruit on liver biomarkers (Aspartate transaminase, Alanine transaminase, Alkaline phosphatase) and kidney biomarkers (Urea and Creatinine) , and histology of the liver and kidneys in diabetic rats.,1. Determine the effects of fractions of C. maxima fruit on levels of blood glucose, insulin, and activities of serum amylase and histology of pancreatic cells in diabetic rats.,To investigate the biochemical effects and antidiabetic mechanism of Cucurbita maxima Duchesne fruit extracts in diabetic rats.,
Kenya 2025-11-07 5:02:42 2028-11-07 Natural Sciences Non-Clinical Trial Degree Award
Beatrice Arwenyo
ID: UNCST-2025-R018319
Nutrient enriched biochar Fertilizer innovation from agricultural feedstock for climate smart farming. VERSION 2.0
REFNo: NS1046ES

The overall objective of the research is to produce Nutrient enriched biochar fertilizer from agricultural waste as an alternative to synthetic fertilizer. Specifically, the study intends to: i) Characterize agricultural waste for their potential use as feedstock ii) Develop Nutrient enriched biochar Fertilizer from selected agricultural waste iii) Validate the efficacy of the Nutrient enriched biochar fertilizer in pilot plots
Uganda 2025-11-07 5:01:35 2028-11-07 Natural Sciences Non-Clinical Trial Non-degree Award
Gertrude Nakigozi
ID: UNCST-2025-R022719
Pregnancy to Protection: Enhancing Vaccine Confidence for Lifelong Family Health
REFNo: HS6734ES

1. Identify factors that influence vaccine confidence among pregnant women and mothers to enhance immunization uptake at the family level, creating a positive ripple effect across the lifespan. 2. Identify opportunities for and barriers to expanding maternal vaccination coverage through evidence-based community focused approaches. For objective two we will utilize qualitative methods to understand key stakeholder level perspectives on overcoming barriers related to the 3c’s and the acceptability, feasibility, and appropriateness (implementation outcomes, operationalized as defined by proctor et al. (60)) of mass education and vaccination campaigns that reach pregnant women outside of ANC facilities to expand vaccine access and catalyze uptake within the family unit. We will also explore how other routine immunization delivery across the lifespan can be similarly optimized. Key informant participants will be identified through existing relationships with the MOH (in the case of policy level stakeholders) and community leaders (in the case of traditional birth attendants and village health team members).
0 2025-11-07 5:00:01 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muzaale tonny
ID: UNCST-2023-R005970
Linking Educational Resources to Competence-Based Curriculum Implementation in Uganda’s Lower Secondary Education: The Role of Instructional Adaptability.
REFNo: SS4467ES

iii. To establish the extent to which instructional expertise in secondary schools mediates the relationship between infrastructural resources availability and competence-based curriculum implementation in lower secondary schools in Uganda ,ii. To establish the extent to which school change educational receptivity mediates the relationship between human resources quality, availability, and competence-based curriculum implementation in lower secondary schools in Uganda ,i. What is the relationship between educational resources and competence-based curriculum implementation in lower secondary schools in Uganda?,
Uganda 2025-11-07 4:57:22 2028-11-07 Social Science and Humanities Degree Award
Claire Biribawa
ID: UNCST-2023-R008347
Advancing the QUALity and EFFectiveness of alcohol and drug treatment services in Uganda (AQUALEFF - Study) through measurement of Patient reported outcomes
REFNo: HS6699ES

To assess the implementation of routine patient-reported outcome measurement and evaluate patient reported outcomes and experiences among individuals receiving treatment services for substance use disorders in Uganda
Uganda 2025-11-07 4:50:35 2028-11-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
The potential of egg powder supplementation, combined with Behaviour Change Communication, to enhance nutrition outcomes during complementary feeding in stunting-endemic areas of Kamwenge District
REFNo: HS6296ES

To develop a Theory of Change for the egg powder initiative, outlining the pathways through which the intervention is expected to improve nutrition outcomes for children 6-17 months in stunting-endemic areas in Kamwenge district.,To project trends in nutrition outcomes with prolonged egg powder supplementation among children 6-17 months in stunting-endemic areas in Kamwenge district.,Determine the change in caregiver nutrition knowledge, attitudes, and practices related to feeding of children 6-17 months receiving egg powder supplementation and social behaviour change communication in stunting-endemic areas in Kamwenge district.,Assess the change in nutrition outcomes of children 6-17 months receiving egg powder supplementation and social behaviour change communication in stunting-endemic areas in Kamwenge district,To assess the potential of egg powder supplementation combined with social behaviour change communication to improve nutrition outcomes during complementary feeding in stunting-endemic areas in Kamwenge district. ,
Uganda 2025-11-07 4:48:44 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tina Aciro
ID: UNCST-2024-R004401
A historical analysis of the Uganda Refugee Model: Policies and practices (1940-2025)
REFNo: SS4457ES

This study seeks to analyse the historical orientation of the Uganda Refugee Model in global refugee policies and practices, with Adjumani Distict as a microcosm of the national model (1940-2025). It examines the national refugee framework’s convergence with and divergence from international frameworks such as the 1951 Refugee Convention and its 1967 Protocol, UNHCR policies, the 1969 OAU’s Convention Governing the Specific Aspects of Refugee Problems in Africa, , and other country’s policies thus, generating insights into the interplay between national innovation and international refugee governance.1. To trace the historical trajectories of refugee settlement in Adjumani District, highlighting the broader framework of Uganda’s refugee governance. 2. To examine the historical underpinnings of the Uganda Refugee Model as policies and practices.3. To analyse the place of the Uganda Refugee Model in global refugee policies and practices (1940-2025).
Uganda 2025-11-07 4:45:34 2028-11-07 Social Science and Humanities Non-Clinical Trial Degree Award
Noah Kiwanuka
ID: UNCST-2021-R010125
ASSESSING THE MYCOBACTERIUM TUBERCULOSIS CARRIAGE STATE
REFNo: HS6616ES

Aim 1: Assess Mtb asymptomatic incipient and subclinical disease, carriage rates and aerosol expulsion from household contacts of active cases in a TB-endemic setting.

Aim 2: Perform WGS on isolates from Mtb active cases and asymptomatic household contacts and compare with the regional/national case database.

Uganda 2025-11-07 4:42:07 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Kintu
ID: UNCST-2025-R016989
The Use of Evidence in Budgetary Decision-making by Legislators: Analysis of Uganda Parliament
REFNo: SS4485ES

To examine legislators' access to evidence for budgetary decision-making.
To evaluate legislators' use of evidence in budgetary decision-making.
To assess how institutional factors affect legislators' access to and use of evidence.
To explore how MP's human agency affects access to and use of evidence.
Uganda 2025-11-04 18:33:31 2028-11-04 Social Science and Humanities Non-Clinical Trial Degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
Feasibility and acceptability of the interRAI self-reported carer needs (SCaN) assessment in central Uganda: A pilot study
REFNo: HS6589ES

The primary purpose of this project is to pilot the interRAI SCaN assessment with informal caregivers of older adults in central Uganda. This work will address five main research objectives (with specific deliverables) in three sequential study phases. Phase 1: (1) Explore the current practices and strategies to assess informal caregiver needs in central Uganda,(2) Document the implementation barriers and facilitators to adopting the interRAI SCaN assessment at study partner sites. Phase 2: (3) Implement the SCaN assessment with two community health organizations in central Uganda, (4) Use the SCaN assessment data to explore the demographic, physical, and mental health and service needs of informal caregivers of older adults in central Uganda. Phase 3: (5) Assess the acceptability of the SCaN assessment with healthcare workers and informal caregivers.
Uganda 2025-11-04 18:32:11 2028-11-04 Medical and Health Sciences Non-Clinical Trial Degree Award
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