Stephen Ojiambo Wandera
ID: UNCST-2021-R012147
|
Wellness4Students Program to Mitigate Stress, Anxiety, and Depression among Makerere University Students in Uganda (Wellness4Students Project)
REFNo: SS4200ES
1.3 Aim and objectives of the study
This study aims to co-create, implement, and evaluate the feasibility and acceptability of a Wellness4Students supportive email/WhatsApp messaging program to mitigate symptoms of stress, anxiety, and depression and to promote well-being among university students in Uganda.
Specific Aims
Aim 1: To co-create and adapt the Wellness4Students intervention for SAD and mental well-being for university students in Uganda. We will co-create the Wellness4Students (W4S) program and then adapt it for students at Makerere University [27, 28, 36].
Aim 2: To determine the prevalence of stress, anxiety, and depression among university students in Uganda. We will use a self-administered online baseline survey to measure these outcomes. The primary outcomes will be Stress, Anxiety, and Depression (SAD) and well-being. This will be measured using the Psychological Stress Scale (PSS-10), Generalized Anxiety Disorder (GAD-7), the Patient Health Questionnaire (PHQ-9), and the WHO Wellbeing Scale [14, 37-40]. We will estimate the prevalence of each of these outcomes separately. to assess the impact of the program on stress, anxiety and depression?
Aim 3:. To assess the feasibility and acceptability of the Wellness4Students intervention for addressing stress, anxiety, and depression among university students in Uganda, as well as to evaluate its impact.
We will assess the daily consistency in program participation (i.e. ability to read daily messages), completion rates (Lost to follow-up), the improvement in mean scores of Stress, Anxiety, and Depression at 3 months, and 6 months [14, 27, 37-40]. End-line survey perceptions and feedback about the program at 6 months will be evaluated. At the end of the intervention and follow up survey, we will conduct a satisfaction survey, as indicated in the last section of the survey questionnaire.
Aim 4: To investigate the association between demographic factors and Stress, Anxiety, and Depression among University students in Uganda.
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Uganda |
2025-09-03 4:46:07 |
2028-09-03 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Hellen Opolot
ID: UNCST-2019-R001724
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An Evaluation of Compliance to Uganda National Research Regulations
REFNo: SS4169ES
Overall objective:
To investigate extent and the drivers of compliance with national research regulations/guidelines among regulators, institutional committees and researchers in Uganda.
Specific objectives
1. To establish the extent of compliance to the national research ethics guidelines/regulations by research regulators, ethics committees and researchers in Uganda
2. To assess the factors associated with Compliance to national research ethics guidelines/regulations by researchers, Institutional Committees and research regulators in Uganda
3. To explore barriers and facilitators of regulatory inspections, audits and enforcement of national research ethics regulations/guidelines by regulators and ethics committees in Uganda
4. To explore barriers and facilitators of compliance to the national research ethics regulations /guidelines by researchers in Uganda
|
Uganda |
2025-09-02 12:03:37 |
2028-09-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Robert MPIIRA
ID: UNCST-2022-R005391
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Dual Generation Interventions and Poverty Alleviation in Refugee Settlements in Uganda
REFNo: SS4265ES
The primary research objective for the proposed study is to determine if households participating in both the ultra-poor graduation program (UPG) and Humanitarian Play Lab (HPL) will have better outcomes for households, caregivers and children than households participating in the humanitarian play lab alone.
Specifically, the study seeks to:
(i) Examine if households which participate in both the Ultra-poor graduation and Humanitarian Play Lab programs have more income and are more food secure than households which only participate in the Humanitarian Play Lab program
(ii) Ascertain if Caregivers of households which participate in both the Humanitarian Play Lab program and the Humanitarian Play Lab program and those which only participate in HPL are different regarding time use, mindset and aspirations, knowledge and practices related to child development, gender attitudes and dynamics, mental health, well-being, stress, and post-traumatic stress disorder.
(iii) Analyse if children in households which participate in both the Humanitarian Play Lab program and the Humanitarian Play Lab program program have higher development outcomes than children of households that only participate in the Humanitarian Play Lab program
|
Uganda |
2025-09-02 10:11:25 |
2028-09-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Fred Bulamba
ID: UNCST-2020-R014888
|
PErioperative respiratory care and outcomes for patieNts Undergoing hIgh risk abdomiNal surgery
REFNo: HS2178ES
To explore the cost-effectiveness of the different treatment combinations in reducing pneumonia and SSI at pre-selected centres.,To assess the impact of both interventions on postoperative mortality at 30-days, and the effect of 80-100% FiO2 only on the re-operation rate at 30 days after surgery.,To assess whether (1) preoperative 0.2% chlorhexidine mouthwash reduces the rate of postoperative pneumonia at 30-days compared to no mouthwash, and (2) 80-100% FiO2 used during surgery reduces the rate of postoperative SSI at 30-days compared to 21-35% FiO2, amongst patients aged 10 years or over undergoing elective or emergency midline laparotomy, with an anticipated abdominal incision of ≥5cm, for any indication except caesarean section.,
|
Uganda |
2025-08-28 10:15:49 |
2028-08-28 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Dickens Akena Howard
ID: UNCST-2019-R000179
|
Neuropsychiatric Genetics of African Populations - Psychosis, II NeuroGAP-Psychosis II
REFNo: HS6452ES
i). Expand knowledge of the genetic architecture of schizophrenia and bipolar disorder in the African continent
through large-scale sample collection and analysis in Uganda
ii) Increase understanding of the genetics of African populations, through various methods for biospecimen
collection
iii) Enhance neuropsychiatric genetic research capacity in Africa through the training of scientists and supporting
the development of locally-led research programs
|
Uganda |
2025-08-27 14:38:09 |
2028-08-27 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Emmanuel Mfitundinda
ID: UNCST-2024-R015971
|
Surveillance for recurrence and residual cervical intraepithelial neoplasia using high-risk human papillomavirus testing at Kawempe National Referral Hospital in Uganda, 2025
REFNo: HS5795ES
To improve surveillance for residual and recurrent CIN during follow up of women attending Kawempe National Referral Hospital (KNRH) in Uganda
Specific objectives
(i) To determine the prevalence of hr-HPV among women with CIN and those without CIN at Kawempe NRH, January-November, 2025
(ii) Determine the diagnostic/prediction accuracy of hr-HPV compared to the standard cytology for residual or recurrent CIN of any grade.
(iii) Determine factors associated with progression of any CIN to a higher grade CIN or invasive cervical carcinoma
(iv) Assess the level of acceptance of hr-HPV screening in women treated for CIN among health workers in the women's clinic at Kawempe National Referral Hospital
|
Uganda |
2025-08-26 16:02:41 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Pamella Abwoyo
ID: UNCST-2024-R015875
|
Prevalence And Associated Factors Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli In Wet Markets In Lira District, Uganda: A One-Health Cross Sectional Study
REFNo: SS3917ES
1. To determine the prevalence and associated factors of ESBL-E.coli in chicken sold in wet markets in Lira District
2. To determine the prevalence and associated factors of ESBL-E.coli in wastewater sources in wet markets in Lira District
3. To determine the prevalence and associated factors of ESBL-E.coli in humans (chicken traders) in wet markets in Lira District
|
Uganda |
2025-08-26 16:01:07 |
2028-08-26 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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David Oguttu Were
ID: UNCST-2024-R005275
|
Onchocerciasis infection status in patients with Nodding Syndrome and epilepsy in Madi-Mid North focus, Uganda
REFNo: HS6224ES
To determine the prevalence of Onchocerca volvulus infection in people with a history of Nodding Syndrome in Madi-Mid North, Uganda
|
Uganda |
2025-08-26 15:55:47 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Jonathan Kitonsa
ID: UNCST-2025-R018208
|
Investigating metabolic outcomes in African adults living with HIV after switching to injectable antiretroviral therapy
REFNo: HS6320ES
1. a) To compare changes in weight, body mass index, lipid profiles, and blood pressure, over one and two years among patients receiving 2-monthly long-acting cabotegravir and rilpivirine and compare this with those remaining on oral ART.
b) To determine factors associated with changes in weight, BMI, lipid profiles, and blood pressure over the one- and two-year periods.
2. To describe the baseline glycaemic status of an African population with a history of suboptimal HIV control, and the change in HbA1c whilst on long acting cabotegravir and rilpivirine compared with patients remaining on oral dolutegravir - based ART through one and two years of follow-up.
3. To compare change in 10-year cardiovascular risk among patients on long acting cabotegravir and rilpivirine with those remaining on oral dolutegravir - based ART after one and two years of follow-up.
4. To quantify the impact of tenofovir disoproxil fumarate cessation on estimated glomerular filtration rate across one and two years of follow-up among patients receiving 2-monthly long-acting cabotegravir and rilpivirine compared with those remaining on oral ART.
5. To compare serum leptin and fasting insulin levels during follow-up in a subset of participants with significant weight gain and sample of similar participants without weight gain at 12 months.
|
Uganda |
2025-08-26 15:48:19 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
VIVIAN ARINAITWE
ID: UNCST-2024-R016282
|
Developing a Feasibility Framework for MedTech in Low-Resource Settings: A Case Study of the NeoNest Device in Mbarara District, Uganda
REFNo: SIR537ES
1.4.1. Main Objective
To evaluate the feasibility of implementing the NeoNest neonatal transport incubator in selected health facilities in Mbarara District, Uganda, and to develop a structured, context-specific feasibility assessment framework for introducing medical technologies in low-resource settings.
1.4.2. Specific Objectives
To assess current neonatal transport and thermal care practices in health facilities in Mbarara District.
To evaluate the simulated performance, usability, and acceptability of the NeoNest device in a controlled setting.
To identify barriers and enablers for the adoption and scale-up of the NeoNest device.
To develop and validate a feasibility assessment framework for medical technology deployment in low-resource settings, using expert consensus (e.g., Delphi ≥ 80% agreement).
|
Uganda |
2025-08-26 15:46:45 |
2028-08-26 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
|
HELEN KEZIE-NWOHA EKENE
ID: UNCST-2024-R016104
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Loalising National Gender and Climate Policy in Uganda
REFNo: SS4066ES
• To examine the extent to which global and national climate policies are leading to change at the local level, improving the lives of women and gender relations, including the distribution of resources.
• To co- produce knowledge with women, women’s organisations, community organisations and local government officials, about the effects of climate change on the lives of women and their communities; identify obstacles; and propose solutions and pathways to climate resilience.
• To use research evidence from the research to influence national level policy making
|
Nigeria |
2025-08-26 15:44:37 |
2028-08-26 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Wilson Ngonzi
ID: UNCST-2024-R016516
|
SMALL HOLDER FARMERS ADAPTATION STRATEGIES TO CLIMATE CHANGE IMPACTS IN KIBAALE, KAGADI AND KAKUMIRO DISTRICTS
REFNo: SS4100ES
To examine the temperatures, drought and precipitation climate change patterns that impacts small holder farmers adaptation strategies in Kibaale, Kagadi and Kakumiro Districts
To examine the small holder farmers adaptation strategies to climate change impacts in Kibaale, Kagadi and Kakumiro Districts.
To examine the small holder farmers adaptation strategies on accessing climate information and early warning systems in Kibaale, Kagadi and Kakumiro Districts
|
Uganda |
2025-08-26 15:42:18 |
2028-08-26 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
MUGULUSI GIDEON
ID: UNCST-2025-R018401
|
SUSTAINABLE INDUSTRIALISATION ON JOB CREATION AND POVERTY REDUCTION IN UGANDA
REFNo: SS4147ES
Purpose of the Study
The general objective of the study is to examine the effects of sustainable Industrialization on job creation and poverty reduction in Uganda
1.3. 1 Specific Objectives
The following specific objectives will guide the study
(i) To examine the effects of Industrial Policy (IP) on job creation and poverty reduction in Uganda
(ii) To investigate the effects of Technological Innovation (TI) on job creation and poverty reduction in Uganda
(iii) To analyze the effects of Infrastructure Development (ID) on job creation and Poverty Reduction in Uganda.
(iv) To determine the effect of Human Capital Development (HCD) on job creation and poverty reduction in Uganda.
(v) To analyze the effect of environmental sustainability on job creation and poverty reduction in Uganda.
(vi) To evaluate the effect of social inclusion on job creation and poverty reduction in Uganda.
(vii) To examine the moderating effect of government support on Job creation and poverty reduction in Uganda
|
Uganda |
2025-08-26 15:38:58 |
2028-08-26 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Micheal Segawa Collins
ID: UNCST-2025-R017185
|
EXPLORING HPV VACCINE UPTAKE AND ITS BARRIERS AMONG ADOLESCENT GIRLS AND YOUNG WOMEN IN URBAN SLUMS OF KAMPALA.
REFNo: HS6259ES
To determine the uptake of both doses of the HPV vaccine among adolescent girls and young women in the urban slums of Kampala.
To identify the barriers to the uptake of the HPV vaccine among adolescent girls and young women in the urban slums of Kampala
|
Uganda |
2025-08-26 15:37:00 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Louis Gorgone
ID: UNCST-2025-R019673
|
Socioendocrinology of female forest living olive baboons (Papio anubis)
REFNo: NS998ES
This research aims to explore the hormonal correlates of dominance, aggression, and affiliative (pro-social) behavior in female forest-living olive baboons (*Papio anubis*) at Kibale National Park, Uganda. Specifically, it investigates how female dominance rank, aggression, and social behaviors relate to physiological stress and aggression markers, measured through glucocorticoids and testosterone. By examining these relationships at multiple temporal scales, the study will shed light on the adaptive significance of social hierarchies and behaviors among females living in an ecologically stable forest environment, thus advancing the understanding of socioendocrine mechanisms underpinning female primate sociality.
|
USA |
2025-08-26 15:34:30 |
2028-08-26 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
BRIGHT NDAHIRO
ID: UNCST-2024-R015220
|
ECOLOGICAL RISK ASSESSMENT OF HEAVY METALS AND POTENTIAL USE OF SELECTED MACROPHYTES IN PHYTOREMEDIATION AND MANAGEMENT OF LAKE GEORGE, UGANDA
REFNo: NS1001ES
General objective
Assess the ecological risk of heavy metal contamination in selected macrophytes, associated water and sediments of Lake George, Uganda
Specific objectives
The specific objectives are to:
1.Determine the distribution and diversity of macrophytes on L. George
2.Determine the pattern of multi elemental concentration (Cu, Ni, Pb and Zn, Co and their variations in wetland plant species of different growth forms, in corresponding water and sediments of Lake George.
3.Apply ecological pollution indices to assess pollution load in the sediments and macrophytes.
4.Identify the selected macrophytes potential use as bio-indicators and for phyto-extraction and phyto-stabilization of heavy metal contamination
|
Uganda |
2025-08-26 15:33:18 |
2028-08-26 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Edwin Nuwagira
ID: UNCST-2021-R013488
|
EFFICACY AND TOLERABILITY OF SHORT-COURSE INTERMITTENT INTRAVENOUS LIPOSOMAL AMPHOTERICIN B VERSUS ORAL POSACONAZOLE FOR CHRONIC PULMONARY ASPERGILLOSIS: A PHASE IIA, PROSPECTIVE, MULTI-CENTRE, RANDOMIZED, CONTROLLED, OPEN-LABEL, FEASIBILITY TRIAL
REFNo: HS6400ES
5. Assess recruitment and retention of patients with CPA on a trial to inform design and sample size for a definitive efficacy trial.,4. To assess adherence to posaconazole therapy,3. To evaluate the utility of different trial endpoints (change in Aspergillus IgG antibody titer, radiological improvement, step test and weight) across groups.,2. To compare 12-month all-cause mortality in each arm,1. To measure emergence of isolates of Aspergillus with resistance/reduced susceptibility to posaconazole in both arms. ,1. Compare the efficacy and tolerability of 1) short course, high dose of intravenous liposomal amphotericin B, 2) short course, high dose of intravenous liposomal amphotericin B followed by daily posaconazole, or 3) posaconazole alone for the treatment of CPA for 6 months.,
|
Uganda |
2025-08-26 13:48:03 |
2028-08-26 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Barnabas Bakamutumaho
ID: UNCST-2021-R012636
|
Countrywide Enhancement of Sentinel Congenital Rubella Surveillance and Intensified Case Identification for Burden Monitoring Following Measles-Rubella Vaccine Introduction in Uganda and Neighboring Countries
REFNo: HS6410ES
Objective: The long-term goal is to sustain systematic CRS case-based sentinel surveillance countrywide to understand the burden of rubella infections causing congenital disabilities and to assess the public health control and prevention interventions such as the vaccines.
Specific aim 1: To support laboratory based CRS diagnosis in clinically suspected cases
Specific aim 2: To monitor vaccine impact in Uganda's routine immunization program
Specific aim 3: To monitor and characterize genotypes associated with CRS
Specific aim 4: To monitor molecular epidemiology of CRS in East African region
|
Uganda |
2025-08-26 13:35:01 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Michael Emenyu Richard
ID: UNCST-2025-R018382
|
Assessing awareness and attitudes of nurses/midwives on effective referral protocols of cleft lip and or palate children; a case study of Teso Sub-Region in Eastern Uganda
REFNo: HS5973ES
Main objective/ purpose
To assess the level of awareness and attitudes of nurses/midwives on effective referral protocols for cleft lip and or palate children in Teso sub-region, Eastern Uganda.
Specific Objectives
i. To assess the level of awareness of nurses/midwives on effective referral protocols for cleft lip and palate children.
ii. To determine the attitudes of nurses/midwives on effective referral protocols for cleft lip and palate children.
iii. To assess the referral protocol/policy for cleft lip and or palate children in Uganda being implemented/used across the health facilities in Teso sub-region.
iv. To determine the socio-demographics of nurses/midwives on effective referral protocols for cleft lip and or palate children.
|
Uganda |
2025-08-26 13:23:57 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Clara Wekesa
ID: UNCST-2021-R013282
|
Correlation between particulate matter and immuno-biochemical markers among people living with HIV and fibrotic liver disease in urban Uganda
REFNo: HS6060ES
Primary objectives:
• To examine the relationship between PM exposure and serum levels of biochemical and haematological parameters (liver chemistry profile, platelet count, fasting blood glucose, glycated hemoglobin and lipid profiles)
• To examine the relationship between PM exposure and serum levels of pro-fibrotic cytokines
Secondary objectives:
• Correlation coefficient between PM and fatty liver change measurements
• Correlation coefficient between PM and fatty liver stiffness measurements
|
Uganda |
2025-08-26 13:19:27 |
2028-08-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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