Grace Ndeezi
ID: UNCST-2019-R001802
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Understanding and managing fevers from infections spread by animals
Multi-centre study
Protocol version 2.0, 17 July 2025
REFNo: HS6492ES
Our overarching goal is to improve the diagnosis and management of zoonotic causes of acute febrile illness (ZAFI) in paediatric populations in sub-Saharan Africa.
The specific aims and objectives are to:
1. Determine the common causes of ZAFI and associated factors in paediatric patients living in urban and rural areas of Uganda, Kenya and Ethiopia
1.1. Quantify the burden of non-malarial fever and identify the major zoonotic aetiologies
1.2. Identify risk factors for and clinical indicators of infection with specific zoonotic pathogens
2. Develop and test novel technologies and approaches for diagnosing ZAFI that are suitable for use in LMIC and field settings
2.1. Evaluate point-of-care (PoC) tests and pilot prototype molecular diagnostic platforms for key zoonotic pathogens
2.2. Determine the best sequence of tests to optimise diagnosis of fever
3. Involve communities and the health sector in Uganda, Kenya and Ethiopia in defining improved approaches to diagnosis and management of ZAFI
3.1. Identify community perceptions on the causes of AFI and care seeking behaviours for fever
3.2. Develop and validate a decision support tool for diagnosis and management of ZAFI in clinical settings
4. Strengthen capacity and capability for research on diagnosis and management of zoonotic diseases in Uganda, Kenya and Ethiopia
4.1. Develop and implement evidence-based capacity strengthening plans to ensure that all partner affiliated laboratories have the capability to perform quality-assured molecular diagnostics research for zoonotic infections
4.2. Develop a cohort of clinical and laboratory scientists with expertise in ZAFI
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Uganda |
2025-10-10 13:30:11 |
2028-10-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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DORCAS LAMUNUOWOT
ID: UNCST-2025-R018451
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Effectiveness of health education intervention on malaria control during pregnancy in rural communities: A case of Lamwo district in Northern Uganda.
REFNo: HS6569ES
1. Assess the current knowledge and awareness, attitude, and practices regarding malaria control among pregnant women in Lamwo District, Northern Uganda.
2. To adapt and implement the culturally tailored health education intervention targeting malaria control and prevention among pregnant women in Lamwo district, Northern Uganda
3. Assess the effectiveness of health education intervention on improving knowledge, attitudes, and practices regarding malaria control among pregnant women in Lamwo district, Uganda.
4. To explore the perceptions and experiences of midwives and pregnant women regarding the implementation and impact of the health education intervention for malaria control and prevention in pregnancy in Lamwo district, Northern Uganda.
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Uganda |
2025-10-08 9:57:08 |
2028-10-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Sarah Kristiansen
ID: UNCST-2023-R007322
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Supporting Ugandan Caregivers in Teaching Menstrual Care Skills to Individuals with Developmental Disabilities
REFNo: SS4157ES
To understand the effects of a program designed to teach parents and educators of individuals with developmental disabilities instructional procedures for teaching menstrual care skills to the young women they care for. Additionally, to understand the effects of a training program to teach an educator from the sponsor organization, Home of Hope, to continue with training procedures to promote sustainability.
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USA |
2025-10-08 8:29:05 |
2028-10-08 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Ahna Ballonoff Suleiman
ID: UNCST-2025-R019613
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Thrive Together: Strengthening Contraception through Lived Experience of Flourishing
REFNo: SS4403ES
1. Bring existing, validated VFP and human flourishing frameworks and evidence into rigorous dialogue;
2. ground understanding of common VFP and human flourishing domains in lived experience expertise of culturally diverse young people, women and couples;
3. Engender first-ever expert consensus on the common domains of human flourishing and VFP;
4. Deliver evidence-based, consolidated guidance to programmers and decision-makers to advance VFP as part of human flourishing, and human flourishing as part of VFP.
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USA |
2025-10-08 19:23:37 |
2028-10-08 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Moffat Nyirenda Joha
ID: UNCST-2020-R019333
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Understanding the Effects of Behavioural Risk Factors and Lifestyle Changes Among Non-overweight and Obese Type 2 Diabetes Mellitus Patients in Malawi and Uganda.
REFNo: HS6497ES
Main Objective:
• To determine whether behavioural risk factors (diet and physical activity) contribute to NOW T2DM and to assess whether current national lifestyle change guidelines have similar effects on glucose control and other outcomes among NOW and obese T2DM patients in Malawi and Uganda.
Specific Objectives:
i. To establish a cohort of newly diagnosed NOW and obese T2DM patients and matched non-diabetic controls in Malawi and Uganda.
ii. To compare baseline dietary and physical activity patterns among NOW and obese T2DM participants and their matched controls.
iii. To administer health education based on national guidelines and compare 6-month outcomes (weight loss and glucose control) in NOW versus obese participants.
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Malawi |
2025-10-08 19:03:35 |
2028-10-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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ANN AKITENG ROSE
ID: UNCST-2025-R019916
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Assessing Healthcare Barriers and Identifying Implementation Strategies to Mitigate Cardiovascular Risks Among Market Vendors in Urban Markets in Kampala and Mbarara, Uganda
REFNo: HS6472ES
The aim of this study is to generate formative quantitative data on the health status, cardiovascular disease (CVD) risk factors, daily routines, and healthcare access and barriers of market vendors in Uganda in order to identify opportunities for culturally appropriate and feasible lifestyle modification interventions and potential implementation strategies to reduce CVD risk.
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Uganda |
2025-10-08 18:59:30 |
2028-10-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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PATIENCE AYESIGA
ID: UNCST-2023-R003499
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The implications of wetland dynamics on water qiuality for conservation of Rwizi macro catchment south western Uganda
REFNo: SS4498ES
To characterize the spatial-temporal dynamics and explore drivers of wetland degradation for middle Rwizi catchment.
2.To assess the implications of wetland degradation on sediment for middle Rwizi catchment.
3.To analyze the influence of nutrients on water quality for middle Rwizi catchment.
4.To evaluate the effectiveness of existing conservation develop suitable restoration and conservation mechanisms for improved catchment health of middle Rwizi system.
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Uganda |
2025-10-08 18:58:01 |
2028-10-08 |
Social Science and Humanities |
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Degree Award |
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Obondo Sande James
ID: UNCST-2019-R000241
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Effect of Mycobacterium tuberculosis and its cell wall glycolipids on the HIV Reservoir in CD4+ T cells
REFNo: HS5439ES
1. To determine if MTB molecules (e.g. PIM6, LAM, MTB lysate) induce HIV expression in memory CD4+ T cells from ART-suppressed HIV infected persons.
2. To determine the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB compared to HIV infected individuals with history of documented treated TB, LTBI, and no LTBI (HIV-monoinfected).
3. To assess longitudinal changes in the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB before initiation of TB treatment and at the end of treatment
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Uganda |
2025-10-08 18:16:22 |
2028-10-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Kansiime Cecilia
ID: UNCST-2025-R017890
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OPTIMIZATION OF THE REARING SUBSTRATES FOR BLACK SOLDIER FLY LARVAE AND ITS ACCEPTABILITY AS AN ALTERNATIVE PROTEIN SOURCE AMONG POULTRY FARMERS IN THE RWENZORI REGION
REFNo: A647ES
(i) To determine the appropriate growing substrates for black soldier fly larvae as a source of protein for poultry.
(ii) To assess farmers perceptions and acceptance of black soldier fly larvae as a source of protein for poultry.
(iii) To determine the economic feasibility of using black soldier fly larvae as a source of protein for poultry.
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Uganda |
2025-10-08 13:11:23 |
2028-10-08 |
Agricultural Sciences |
Non-Clinical Trial |
Degree Award |
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Richard Selwanga
ID: UNCST-2025-R018576
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THE EVOLUTION OF THE LINGUISTIC LANDSCAPE OF KAMPALA: LANGUAGE POLICY, MULTILINGUALISM, AND PUBLIC PERCEPTIONS
REFNo: SS4333ES
(i) To examine the language of public signs in the LL Kampala District from the colonial to post-colonial period.
(ii) To analyse the impact of language policies on language visibility in the LL of Kampala District from the colonial to post-colonial period.
(iii) To investigate the role that multilingualism has played in shaping the LL of Kampala District from the colonial to post-colonial period.
(iv) To explore the perceptions of the target readership towards language use in the contemporary LL of Kampala District.
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Uganda |
2025-10-08 13:06:29 |
2028-10-08 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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