Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,466
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nixon Niyonzima
ID: UNCST-2020-R014577
A PHASE III, RANDOMIZED, OPEN-LABEL STUDY EVALUATING THE EFFICACY AND SAFETY OF GIREDESTRANT IN COMBINATION WITH PHESGO VERSUS PHESGO AFTER INDUCTION THERAPY WITH PHESGO-TAXANE IN PATIENTS WITH PREVIOUSLY UNTREATED HER2-POSITIVE, ESTROGEN RECEPTOR-POSITIVE LOCALLY-ADVANCED OR METASTATIC BREAST CANCER (HeredERA)
REFNo: HS2968ES

To identify and/or evaluate biomarkers that are predictive of response to Phesgo and giredestrant (i.e., predictive biomarkers), are early surrogates of efficacy, are associated with progression to a more severe disease state (i.e., prognostic biomarkers), are associated with acquired resistance to Phesgo and giredestrant, are associated with susceptibility to developing adverse events or can lead to improved adverse event monitoring or investigation (i.e., safety biomarkers), can provide evidence of Phesgo and giredestrant activity (i.e., pharmacodynamic biomarkers), or can increase the knowledge and understanding of disease biology and drug safety,To evaluate potential effects of ADAs,To evaluate the immune response to pertuzumab, trastuzumab, and rHuPH20,To evaluate the potential relationships between Phesgo and giredestrant exposure and the safety, efficacy, immunogenicity, or biomarker endpoints.,To characterize the giredestrant, pertuzumab, and trastuzumab PK profile when given in combination,To evaluate the safety of Phesgo plus giredestrant compared with Phesgo from the participant's perspective,To evaluate health utility of participants treated with Phesgo plus giredestrant compared with Phesgo to generate utility scores for use in economic models,To evaluate effects of Phesgo plus giredestrant compared with Phesgo on work productivity and activity,To evaluate the safety of Phesgo plus giredestrant compared with Phesgo,To evaluate the efficacy of Phesgo plus giredestrant compared with Phesgo,
Uganda 2023-07-14 12:43:26 2026-07-14 Medical and Health Sciences Clinical Trial Non-degree Award
David Ssejinja Robinson
ID:
SOCIOECONOMIC REINTEGRATION AND LIFE SATISFACTION OF MIGRANT WORKERS: A CASE OF UGANDAN RETURNEES FROM THE MIDDLE EAST
REFNo: SS1817ES

To analyse the influence of social reintegration on life satisfaction among Uganda migrant worker returnees from Middle East

ii.To assess the relationship between economic reintegration and life satisfaction among Uganda migrant worker returnees from Middle East

iii. To examine the fit between socio economic reintegration and migrant worker returnees policy and process in Uganda for returnees from the Middle East.

iv.To investigate the mediating effect of socio economic reintegration on the fit of migrant worker returnees policy and process and life satisfaction of Ugandan migrant worker returnees from Middle East

Uganda 2023-07-14 12:37:54 2026-07-14 Social Science and Humanities Non-Clinical Trial Degree Award
Emma Riley-Green
ID:
The demand for digital identification amongst small enterprise owners in Uganda
REFNo: SS1836ES

Understand how the provision of UGPass affects business owners, including their likelihood of writing contracts with suppliers and customers.,3.Look at whether uptake and usage of UGPass varies depending on whether: a) contracting is highlighted as a potential benefit of UGPass, or b) sign-up assistance is provided to the enterprise owner.,2. Assess whether willingness to pay for the UGPass digital ID varies depending on whether: a) contracting is highlighted as a potential benefit of UGPass, or b) sign-up assistance is provided to the enterprise owner.,1. Gather data on the willingness of micro, small and medium enterprise owners in Kampala to pay for the new UGPass digital ID.,Informality hinders firm profitability and growth in a variety of ways, including limiting firms to suppliers in their social networks due to issues of trust and fraud. Digital IDs offer potential paths to increasing formality, such as by allowing the verification of identities and the authentication of signed contracts, thus helping businesses to sign contracts with new suppliers with lower prices or a better selection of goods. However, there is no research to date examining the demand for a digital ID and verified authentication services among business owners. ,
UK 2023-07-14 12:36:18 2026-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Angella Natukunda
ID:
DETERMINANTS OF NUTRITION STATUS AMONG ADOLESCENTS IN SELECTED SECONDARY SCHOOLS OF KANUNGU DISTRICT SOUTH WEST REGION UGANDA
REFNo: SS1812ES

Broad obective To investigate the determinants of nutrition status among adolescents in selected secondary schools in Kanungu District South West Uganda. Specific objectives To assess the nutrition status of adolescents in the selected secondary schools of Kanungu District South West Region Uganda. To determine the social demographic and economic factors influencing nutrition status of adolescents in the selected secondary schools of Kanungu District South West Region Uganda. To determine the diet-related factors influencing nutrition status of adolescents in the selected secondary schools of Kanungu District South West Region Uganda. To determine the level of adolescent nutrition knowledge associated with nutrition status among adolescents in the selected secondary schools of Kanungu District South West Region Uganda.
Uganda 2023-07-14 12:34:44 2026-07-14 Social Science and Humanities Clinical Trial Degree Award
Moses Mulumba
ID: UNCST-2022-R008759
Litigating Reproductive Justice in Africa: A Ugandan case study
REFNo: SS1714ES

To assess the potential impact of litigation on expanding access to SRHR and achieving reproductive justice in Uganda and Africa in general.,To determine what potential SRHR issues can be litigated in the Uganda through a reproductive jus-tice lens.,To provide an in-depth assessment of the legal, social, political and cultural landscape of SRHR in Uganda and Africa at large.,To contribute to the expansion of access to SRHR through litigating reproductive justice in Africa using Uganda as the case study.,
Uganda 2023-07-14 12:33:09 2026-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."