Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
LYDIA NAKIGANDA
ID: UNCST-2025-R016917
FEASIBILITY AND ACCEPTABILITY OF A PEER-DELIVERED HOME-BASED PrEP MODEL (HB-PREP) FOR FEMALE SEX WORKERS IN RURAL UGANDA
REFNo: HS7906ES

1. To adapt and co-develop a peer-delivered, home-based PrEP care model for female sex workers in rural Uganda 2. Conduct a pilot RCT to evaluate the acceptability and feasibility of the HB-PrEP care model for FSW in Uganda. 3. Qualitatively examine participants’ and interventionists’ experiences with the care model and identify facilitators and barriers to its implementation
Uganda 2026-07-16 19:28:09 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
A phase 3, randomized, placebo-controlled, double-blinded trial to evaluate the safety, tolerability, and immunogenicity of a multivalent Group B Streptococcus vaccine in healthy pregnant women and their infants.
REFNo: HS8122ES

To evaluate the aggregate predicted VE combining all 6 serotypes in GBS6 to provide protection from invasive GBS EOD based on serotype-specific anti-CPS IgG concentrations measured in infants at birth,To evaluate the aggregate predicted VE combining all 6 serotypes in GBS6 to provide protection from invasive GBS LOD based on serotype-specific anti-CPS IgG concentrations measured in infants at birth.,To assess the ability of GBS6 to induce anti-CPS IgG antibody levels predicted to provide protection from invasive GBS early-onset disease (EOD) caused by the 6 individual vaccine serotypes (Ia, Ib, II III, IV, and V) in infants when GBS6 is administered to healthy pregnant women.,To assess the ability of GBS6 to induce anti-CPS IgG antibody levels predicted to provide protection from invasive GBS late-onset disease (LOD) caused by the 6 individual vaccine serotypes (Ia, Ib, II III, IV, and V) in infants when GBS6 is administered to healthy pregnant women.,To assess the safety of maternal immunization in infant participants born to pregnant women who were vaccinated with GBS6 during pregnancy.,To describe the safety and tolerability of GBS6 in maternal participants,
Uganda 2026-07-16 19:21:43 2029-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Semanda Davis
ID: UNCST-2026-R024893
Management practices and infrastructure development of secondary schools in Uganda. A case of selected Adventist secondary schools in central region .
REFNo: SS5448ES

General Objective To examine the relationship between Management practices and infrastructure development in Adventist Secondary Schools in the Central Region of Uganda. Specific Objective i) To determine the relationship between Planning and infrastructure Development of SDA Secondary Schools in the central region of Uganda. ii) To assess the relationship between Coordination and infrastructure Development of secondary schools in the Central Region of Uganda. iii) To explore the relationship between monitoring and evaluation on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda. iv) To Analyze the Moderating effect of SDA Church Policy on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda.
Uganda 2026-07-16 19:14:14 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
Evaluation of MiniDock MTB for Decentralized Molecular Testing During Community-Based Active TB Case-Finding in Uganda
REFNo: HS8104ES

To estimate the incremental cost per TB case successfully initiated on treatment and the incremental cost-effectiveness of integrating MiniDock MTB� into community-based TB screening, compared with the standard of care, from a health system perspective.,To assess the feasibility, acceptability, and adoption of integrating MiniDock MTB� into community-based active TB case-finding from the perspectives of (a) participants undergoing testing and (b) healthcare providers implementing the intervention.,To determine whether integrating MiniDock MTB� near point-of-care molecular testing into community-based TB screening reduces the time from initial screening contact to TB treatment initiation, compared with the standard of care (centralized GeneXpert testing).,
Uganda 2026-07-16 17:26:06 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JIMMY ADOKO
ID: UNCST-2025-R022752
RETENTION IN CARE AND ASSOCIATED FACTORS AMONG ADOLESCENTS RECEIVING ANTE-RETROVIRAL THERAPY (ART) IN SELECTED HEALTH FACILITIES IN ADJUMANI DISTRICT, UGANDA
REFNo: HS7420ES

1. To Identify socio-demographic factors associated with retention in care among adolescents on ART.
2. To Identify adolescent factors associated with retention in ART.
3. To Identify the community factors associated with adolescent retention on ART.
4. To Identify the health systems factors associated with retention in HIV care for adolescents on ART.
Uganda 2026-07-16 15:36:28 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
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