Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mordecai Tayebwa
ID: UNCST-2024-R002437
 Expanded Strengthening of Makerere University's Research Administration Capacity Program (E-SMAC)
REFNo: HS5531ES

Test knowledge and skills change over time of faculty prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff and faculty prior to and following the SOP trainings and implementation activities ,
 Uganda 2025-01-30 18:30:42 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Evidence Synthesis To Inform Strengthening Medical Oxygen Systems in low- and middle-income countries”. (ESTISMOS)
REFNo: HS5437ES

10. To assess the implementation outcomes and impact of the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria,9. To determine the health facility readiness, also known as “change valence”, to implement the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria.,8. To assess the capability (real and perceived) of the selected health facilities, also known as, “change efficacy” to implement the Oxygen-as-a- service intervention in Uganda. ,7. To examine the coordination mechanisms at national, district, health facility levels that facilitate availability of medical oxygen at health facilities.,6. To examine the stakeholder positions, interests, and influences along the medical oxygen supply chain on access to medical oxygen at health facilities.,5. To characterize processes and tools for information flow and management for medical oxygen and oxygen related equipment.,4. To map the medical oxygen supply chain system and explore the nodes and links from the medical oxygen sources to health facilities where it is needed.,3. To synthesize the extent to which healthcare packages have incorporated oxygen therapy solutions to promote their adoption, scale up and sustainability. ,2. To summarize the implementation outcomes of oxygen therapy solutions from published intervention studies in LMICs. ,1. To synthesize determinants of implementation outcomes of oxygen therapy solutions in low- and middle-income countries.,
 Uganda 2025-01-30 18:27:31 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adityavarman Mehta Umesh
ID: UNCST-2024-R002841
 The Role of Global Health Diplomacy in Achieving Peacebuilding in Post-Conflict Northern Uganda
REFNo: SS3590ES

In this context, the thesis will examine the use of global health diplomacy, which aims to bridge the disciplines of public health, international relations, and public policy, as a peacebuilding instrument in northern Uganda. With numerous health initiatives such as those that addressed the increasing incidence of HIV/AIDS and Ebola during the civil war between 1986 and 2006, and psychosocial programs following the conclusion of the war, there is scope to determine whether these health initiatives contributed to the cessation of violence and ultimately, peacebuilding. This thesis will arrive at this determination by assessing if health initiatives implemented in northern Uganda during and after the conflict fostered social cohesion and afforded Ugandans, particularly women, agency or the opportunities to follow through on their choices. The twenty-year conflict in northern Uganda provides an effective context for this thesis because the violence was largely a product of its political and social history (Kustenbauder, 2010). The violence had ethnic and religious dimensions as well, with academic literature on the subject suggesting that the largest rebel group fighting the national army, the Lord’s Resistance Army, viewed its struggle against the government of Uganda as a divine cause, which was guided by God through its leader, Joseph Kony (Van Acker, 2004). Against this political and historical backdrop, this thesis will aim to determine if global health diplomacy was able to, in whole or in parts, achieve peacebuilding objectives in northern Uganda.
Uganda 2025-01-30 18:24:54 2028-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
Hilary Muheezangango
ID: UNCST-2024-R002492
 GOVERNANCE PRACTICES AND ECONOMIC SECURITY IN PINEAPPLE VALUE CHAIN COMMUNITIES IN SELECTED DISTRICTS; CENTRAL UGANDA.
REFNo: SS3466ES

Main Objective: To examine the relationship between governance practices, and economic security of Pineapple Value Chain Communities in Central Uganda.

Specific objectives
i. To examine the contribution of shared goals among stakeholders on the economic security of Pineapple Value Chain Communities in the Districts of Luweero, Kayunga and Mukono; Central Uganda.
ii. To examine the relationship between shared roles and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iii. To analyze the relationship between shared knowledge and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iv. To assess the mediating effect of work environment on the relationship between governance practices and economic security in Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.

 Uganda 2025-01-24 14:40:20 2028-01-24 Social Science and Humanities Non-Clinical Trial Degree Award
Norah Babirye
ID: UNCST-2024-R015349
 Optimising Indigenous Food Consumption for Improved Metabolic Health among Adults in Uganda.
REFNo: A549ES

1. To evaluate indigenous vegetable and fruit consumption patterns among adults in Wakiso district, Uganda.
2. To identify the sources of indigenous vegetable and fruit consumed among adults in Wakiso district, Uganda.
3. To document the cardiometabolic health profile of adults in Wakiso district, Uganda.

Uganda 2025-01-24 14:38:11 2028-01-24 Agricultural Sciences Non-Clinical Trial Degree Award
Laura Twubahe
ID: UNCST-2024-R002589
 Nutritional, Physical-chemical, and Microbiological changes in the properties of cooking oil and street-vended deep-fried foods in Wakiso District, Central Uganda: A case study of Kira Municipality.
REFNo: HS5308ES

General objective
The general objective of this study is to evaluate the physical-chemical changes in cooking oil and the Microbiological safety of street vended deep fried foods in Kira Municipality, Wakiso District, Uganda.

Specific Objectives
The specific objectives of the study are to;
1. Assess the changes in the physical-chemical properties including trans fatty acids of cooking oil used by street vendors of Rolex and deep-fried chicken in Kira Municipality.
2. Assess the microbiological safety of street vended rolex and deep-fried chicken in Kira municipality.
3. Assess the knowledge, attitudes, and practices of street vendors of rolex and deep-fried chicken in Kira Municipality.

 Uganda 2025-01-22 9:56:29 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Robertson Turyamwijuka
ID: UNCST-2024-R015990
 A sustainable Public procurement implementation framework for Public Sector Entities in Uganda.
REFNo: SS3597ES

3.1 PRIMARY OBJECTIVE The primary objective of this study seeks to develop and propose a sustainable public procurement implementation framework that will guide Ugandan public entities on how to enhance sustainable public procurement performance through the effective implementation of sustainable public procurement practices and approaches. This will enable these public entities to also address the unique challenges and opportunities they face, with the aim to enhance efficiency, accountability, and sustainability in public procurement processes. The accomplishment of the ensuing secondary objectives will enable this. 3.2 SECONDARY OBJECTIVES OF THE STUDY The following secondary objectives have been determined in order to fulfil the study's main goal: 3.2.1 To identify the drivers influencing the implementation of sustainable public procurement in public sector entities in Uganda. 3.2.2 To identify the sustainable public procurement practices currently implemented among Ugandan public sector entities. 3.2.3 To identify the challenges and their consequences faced by Ugandan public sector entities when implementing sustainable public procurement. 3.2.4 To identify sustainable public procurement approaches within public sector entities in Uganda. 3.2.5 To determine the influence of sustainable public procurement drivers on sustainable public procurement performance. 3.2.6 To determine the influence of the drivers of sustainable public procurement on sustainable public procurement approaches. 3.2.7 To assess the influence of sustainable public procurement drivers on the adoption of sustainable public procurement practices. 3.2.8 To assess the influence of sustainable public procurement approaches on sustainable public procurement practices. 3.2.9 To assess the influence of sustainable public procurement practices on sustainable public procurement performance. 3.2.10 To assess the influence of sustainable public procurement approaches on sustainable public procurement performance. 3.2.11 To assess how sustainable public procurement approaches, in Ugandan public sector organizations, mediate the relationship between sustainable public procurement drivers and sustainable public procurement performance. 3.2.12 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement drivers and sustainable public procurement performance in Ugandan government agencies. 3.2.13 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement approaches and sustainable public procurement performance within public sector entities in Uganda. 3.2.14 To provide a conceptual framework for Ugandan public sector entities to embrace sustainable public procurement.
Uganda 2025-01-22 17:09:13 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Adoch
ID: UNCST-2024-R003825
 Land Conflicts and Livelihood Nexus in Gulu City, Northern Uganda
REFNo: SS3531ES

To assess the attitude and perceptions of inhabitants on effectiveness of land conflict resolution mechanisms in Gulu city,To assess the effects of land conflicts on livelihood capitals of inhabitants in Gulu city,To examine the drivers of land conflict among inhabitants in Gulu city,To determine the nature of land conflicts among inhabitants in Gulu city,The study aims to examine the nature and extent of land conflicts, explore how these conflicts affect the livelihood assets of the local population, and assess the effectiveness of existing mechanisms for conflict resolution. This study seeks to provide insights that can inform policy, and interventions aimed at improving land management and enhancing the livelihoods of the affected communities.,
 Uganda 2025-01-22 17:07:20 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Evaluating the performance, feasibility, acceptability and impact of treatment-decision algorithms for pulmonary tuberculosis in children in Uganda and their unmet social needs;TDA4Child
REFNo: HS5390ES

(i) To compare the diagnostic accuracy of the study TDAs with the Uganda national algorithm for the diagnosis of TB in children
(ii) To compare adults and children TB notifications before and after study initiation;
(iii) To describe the caregiver’s (parents or guardians) acceptability in introducing TB treatment based on the TDA outcome
(iv) To describe healthcare workers’ (HCWs) experience, acceptability of and satisfaction with and feasibility of algorithm the TDAs’ implementation
(v) To describe the unmet social needs, social protection coverage, and dissaving among children under 10 years old being evaluated for pulmonary TB and their households in Uganda.
Uganda 2025-01-22 17:04:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Validation of the Quality of Dying and Death-Revised Global Version scale in Uganda
REFNo: SS3429ES

3) To assess the relationship between quality of death and dying and grief and bereavement symptoms reported by caregivers,2) To determine the reliability of the QODD-RGV,1) To examine face and content validity of the QODD-RGV index.,The main objective of this study is to undertake a psychometric evaluation of the Quality of Death and Dying Index. ,
 Uganda 2025-01-22 16:56:37 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Clinical Performance Evaluation of Kwiq-Test HIV-1/2 (Whole Blood/Serum/ Plasma): Diagnostic sensitivity & diagnostic specificity, specimen equivalence, Anticoagulant equivalence and qualification of usability
REFNo: HS5368ES

The objectives of this study are:
1. To establish the diagnostic sensitivity and diagnostic specificity of the Kwiq HIV-1/2 test (Serum/Plasma/wholeblood) in plasma samples according to the WHO TSS-1 Part 2.1
2. To demonstrate the equivalence of serum, plasma (EDTA-K2), venous whole blood (EDTA-K2) and fingerprick whole blood collected from HIV positive patients according to WHO TSS-1 Part 1: 1.1.1.
3. To demonstrate anticoagulant equivalence of serum, venous whole blood (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin), plasma (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin) and fingerprick whole blood
4. To demonstrate the usability of this rapid diagnostic test when performed by the intended users. It will be assessed whether the intended users comprehend all key messages from labelling and packaging (i.e. label comprehension study) and whether they can correctly interpret pre-determined test results (i.e. result interpretation study).
To meet all the requirements as set out in the WHO TSS-1study will be conducted in Uganda

 Uganda 2025-01-22 16:53:12 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 Developing Better Control Together, a multi-faceted patient-support group for patients with hypertension in Uganda
REFNo: HS5309ES

We propose to develop a multi-faceted patient-support group for patients living with HTN in rural Uganda using an iterative approach that is tailored to the local context. We will adapt several evidence-based interventions for patient-support groups from the HIV experience to develop a comprehensive intervention for patients with HTN by including aspects of disease education, social support, financial activities, and bulk purchasing of HTN medications.
 USA 2025-01-22 16:51:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Rwankangi
ID: UNCST-2024-R016056
 Solar-Powered Irrigation Schemes for Smallholder Farmers in Uganda: Assessing Impact and Sustainability
REFNo: SIR452ES

1. To examine the impact of adopting solar-powered irrigation systems on crop
yields in horticulture among smallholder farmers in eastern Uganda.

2. To examine how farmers’ knowledge and skills in operating and maintaining
solar irrigation systems influence the adoption of solar-powered irrigation
technology among smallholder farmers.

3. To analyze the effect of stakeholder engagement on the adoption of solar-
powered irrigation technologies among smallholder farmers.

4.To assess how the Ugandan Government’s policy frameworks influence, the
adoption of solar-powered irrigation technology among smallholder farmers.

 Uganda 2025-01-22 16:49:32 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 Functional Role, Temporal Dynamics, and Protective Impact of IgA on Clinical Outcomes in Uncomplicated Plasmodium falciparum Malaria
REFNo: HS5353ES

General Objective
To investigate the functional role, temporal dynamics, and protective impact of IgA on clinical outcomes in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda.
Specific Objectives
1. To quantify the functional activity of serum IgA antibodies in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda, by measuring the percentage reduction in hepatocyte infection, the inhibition of merozoite invasion of erythrocytes, and the level of neutrophil activation through oxidative burst and cytokine release.
2. To characterize the temporal dynamics and persistence of IgA responses in adult patients with uncomplicated malaria in the greater Kampala region over a 42-day follow-up period, by measuring peak IgA levels (C_max), time to peak level (T_max), rate of decline (IgA half-life), and area under the curve (AUC).
3. To evaluate the association between serum IgA levels and clinical outcomes in adult patients with uncomplicated malaria in the greater Kampala region, by assessing symptom resolution time and parasite clearance time.
4. To determine the correlation between IgA levels and complement activation, as well as their association with pro-inflammatory or regulatory cytokines during and after Plasmodium falciparum infection in adult patients with uncomplicated malaria in the greater Kampala region, Uganda.

 Uganda 2025-01-22 16:47:42 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dina Nabasumba
ID: UNCST-2023-R006504
 Crop production dynamics and vulnerability to food insecurity in the face of climate variability: A case of smallholder farmers in south-western Uganda
REFNo: A524ES

4. To classify the extent and factors controlling the influence of climate variability on vulnerability to food insecurity among smallholder farmers in south-western Uganda,3. To determine the influence of spatial-temporal rainfall variability on adoption patterns of land-based climate smart agricultural practices in seasonal cropping systems of smallholder farmers in south-western Uganda ,2. To establish the relationship between smallholder farmers’ knowledge, attitudes and adoption of climate smart agricultural practices in south-western Uganda,1. To assess smallholder farmers’ perceptions of climate variability and the extent to which it has altered crop selection and cultivation patterns in south-western Uganda,To establish the influence of climate variability on the crop production systems and vulnerability to food insecurity among smallholder farmers in south-western Uganda,
 Uganda 2025-01-22 16:46:28 2028-01-22 Agricultural Sciences Non-Clinical Trial Degree Award
Chikadibia Uche Kalu Awa
ID: UNCST-2024-R003818
 OPTIMIZATION OF MIX DESIGN FOR STRUCTURAL LIGHTWEIGHT CONCRETE (SLWC) WITH ARTIFICIAL AGGREGATES USING RESPONSE SURFACE METHODOLOGY
REFNo: SIR344ES

1. To produce and characterize artificial aggregates from polyethylene terephthalate plastic waste.
2. To design experimental mixture proportions for S.L.W.C. using mathematically independent variable (factorial) approach.
3. To evaluate the performance of S.L.W.C. regarding density, splitting tensile strength, compressive strength, workability, and durability.
4. To apply response surface methodology for the analysis of the obtained results to derive model equations for each performance criteria.
5. To optimize (S.L.W.C.) using desirability function.
6. To carry out microstructural analysis of the specimens.

 Nigeria 2025-01-22 16:45:23 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
SIMON MUCHURO
ID: UNCST-2024-R003624
 Estimation of TB notification rates among healthcare workers in 2023 and assessment of associated healthcare worker and health facility characteristics
REFNo: HS5200ES

Primary objective:
1. To establish the TB notification rates among healthcare workers
2. To establish the risk factors associated with TB disease
Secondary objectives:
3. To determine TB treatment outcomes among healthcare workers started on drug sensitive TB treatment from 1st January to 31st December 20
 Uganda 2025-01-22 16:44:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Muwonge Ssajjabbi
ID: UNCST-2023-R007179
 AN INVESTIGATION INTO THE IMPACT OF TELEMEDICINE ON PATIENT OUTCOMES IN KAMPALA DISTRICT. A CASE OF RUBAGA DIVISION
REFNo: HS4901ES

iii. To investigate the extent to which telemedicine improves patient satisfaction for patients in Lubaga division. ,ii. To assess the impact of telemedicine on accessibility of health care services for patients in Lubaga division. ,i. To identify the barriers and facilitators of telemedicine adoption and how they impact patient outcomes in Lubaga division. ,To investigate the impact of telemedicine on patient outcomes in Kampala district, with emphasis on Lubaga division so as to improve the quality of health-care service delivery.,
 Uganda 2025-01-22 16:38:30 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
ROSE AKULLO
ID: UNCST-2024-R005155
 LEADERSHIP BEHAVIOR IN MANAGEMENT OF CURRICULUM CHANGES IN THE LOWER SECONDARY SCHOOLS IN KARAMOJA REGION, NORTH EASTERN UGANDA.
REFNo: SS3120ES

5. Determine the mediating effect of organizational climate on the relationship between leadership behaviours and curriculum change management in the lower secondary curriculum,4. To assess the impact of leadership behaviour on the level of teacher support for curriculum change management in lower secondary schools in the Karamoja Region, Uganda.,3. Establish the effect of change-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja ,2. Assess the effect of task-oriented leadership behaviours on management of curriculum changes in lower secondary schools in the Karamoja Region, Uganda.,1.Examine the effect of relation-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja,To investigate the effect of leadership behaviors on management of curriculum changes in secondary schools in Karamoja region, North Eastern Uganda.,
 Uganda 2025-01-22 16:33:52 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
BONIFACE OJOK
ID: UNCST-2023-R006075
 Lok Ber Bedo Study: Storytelling with young people affected by conflict in Acholi sub-region, northern Uganda
REFNo: SS3437ES

1. General objective: The proposed project seeks to engage groups of young people affected by conflict in Acholi sub-region to explore the extent to which storytelling can be harnessed to promote shared understanding of the wholesome character of ber bedo (Acholi meaning 'wellbeing) and collective action to advance ber bedo.

2. Specific objectives
(1) To explore conflict affected young people’s understanding of ber bedo and practice of storytelling in Acholi sub-region.
(2) To identify challenges to ber bedo among young people affected by conflict in Acholi sub-region and to explore existing and potential strategies to address these.
(3) To assess to what extent the 'lok ber bedo' (Acholi meaning 'let's talk well-being') storytelling approach can be transformational, in its various dimensions, for young people affected by conflict in Acholi sub-region.
Uganda 2025-01-22 16:24:55 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
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