Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sarah Nabukeera
ID: UNCST-2025-R021403
Effectiveness of Postpartum Family Planning on Family Planning Uptake among Adolescent Girls and Young Women (AGYW) (10-24 years) in Rural Busoga Sub-region.
REFNo: HS7412ES

General Objective To evaluate the effectiveness of PPFP on FP uptake among AGYW (10-24 years) in the Busoga sub-region. This information will assist FP policymakers, programmers, and implementers in Uganda to thoroughly and critically examine the existing PPFP service delivery systems and processes and optimize investments for improved access and use of FP among AGYW. Specific Objectives The specific objectives will be under three sub-studies: Specific Objective I (Sub-study I) i. To synthesize the existing evidence on PPFP among AGYW (10-24 years) in Uganda. To determine the level of PPFP uptake among AGYW aged 10-24 years in Uganda between 2015 and 2025, by conducting a meta-analysis of the available evidence ii. To assess the existence of inequities in the level of PPFP uptake among AGYW 10-24 years in Uganda, using the available evidence. iii. To synthesize the existing evidence on the factors related to PPFP uptake among AGYW aged 10-24 years in Uganda Specific Objective II (Sub-study II) To explore the PPFP literacy needs, preferences, concerns and experiences of AGYW in the Busoga sub-region i. To explore the PPFP literacy needs of AGYW in the Busoga sub-region. ii. To find out preferences and concerns about PPFP literacy among AGYW in the Busoga sub-region. iii. To examine PPFP literacy experiences of AGYW in the Busoga sub-region. Specific Objective III (Sub-study III) To evaluate the effectiveness of the PPFP on FP uptake by AGYW (10-24 years) in the Busoga sub-region. i. To explore perspectives of policymakers, programmers, implementers and AGYW on fidelity, acceptability, adoption, penetration, relevance and equity of the PPFP among AGYW (10-24 years) in the Busoga sub-region. ii. To establish the effectiveness of the PPFP on FP uptake among AGYW (10-24 years) in the Busoga sub-region.
Uganda 2026-04-27 11:02:36 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
John Bosco Isunju
ID: UNCST-2019-R001803
Gender Equality, Equity and Social Inclusion (GEEI) in Climate-Health financing in Uganda: pathways, barriers and opportunities.
REFNo: HS7363ES

To assess the perceptions and understanding of GEEI among stakeholders involved in climate-health projects, policies and programs.,To identify strategies for designing and implementing climate–health projects that deliberately reduce gender inequalities and prioritise the specific needs of women and vulnerable population groups.,To identify the opportunities, barriers and facilitators influencing access to, allocation of, and accountability for equitable climate–health financing in Uganda.,To examine how existing governance, policy, and institutional frameworks enable or constrain equitable financing for climate–health action in Uganda.,To assess the extent to which gender equality, equity and social inclusion considerations are integrated into climate–health policies, programmes, and interventions in Uganda.,To assess the integration and operationalisation of gender equality, equity and social inclusion within Uganda’s climate–health agenda and to identify ways in which climate and health financing can be structured to reduce gender disparities and prioritise the needs of women and other vulnerable population groups.,
Uganda 2026-04-27 10:36:43 2029-04-27 Medical and Health Sciences Non-degree Award
Joanitah  Nalunjogi
ID: UNCST-2023-R008356
Uptake of Clean Household Energy Use and its Impact on Respiratory and Cognitive Health Kawempe Division in Uganda
REFNo: HS7378ES

1. To determine the uptake of clean fuels among households in Kawempe division, Kampala City, Uganda. 2. To compare the respiratory health of people (all ages) living in biomass fuel-dependent households with that of clean fuel-dependent households. 3. To compare the cognitive function of people (all ages) living in biomass fuel-dependent households with that of clean fuel-dependent households
Uganda 2026-04-27 10:32:03 2029-04-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
Feasibility of cervical cancer point-of-care testing
REFNo: HS7499ES

Primary Objective
1. To evaluate the feasibility of performing cervical cancer screening based on self-sampling.

Secondary objectives
1. To assess the feasibility of implementing information sessions to motivate cervical cancer screening with VIA.
2. To assess the feasibility of implementing information sessions to encourage self-sampling for HPV DNA testing.
3. To assess the feasibility outcomes as described by Gadke et al. of each of the three components (see Table 3).
4. To understand the potential role of Community Health Workers (CHWs) in the uptake of Cervical Cancer screening services based on the perspectives of healthcare providers, women, policy makers, and community stakeholders in Uganda.

Uganda 2026-04-24 15:18:34 2029-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annet Sumba
ID: UNCST-2026-R023884
A City as a Peace Project
REFNo: SS5095ES

1. To examine how cityness is lived and expressed by different actors in a post-conflict city context; 2.To investigate how informal and marginal actors contribute to the remaking of urban space and social relations; and 3. To analyse how public spaces and infrastructures function as affective and symbolic sites of peace-building.
Uganda 2026-04-24 14:34:33 2029-04-24 Social Science and Humanities Non-Clinical Trial Degree Award
Allen Kabagenyi
ID: UNCST-2019-R000665
A Gendered Analysis of Preparedness and Response to Natural Disasters in Kasese District
REFNo: SS4854ES

To examine household-level flood and landslide response strategies in Kasese District, with a focus on the extent of response mechanisms, the socio-economic and cultural factors influencing their effectiveness, and gender-based differences in disaster response approaches.
Uganda 2026-04-24 14:28:53 2029-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
A5424 Menopausal Hormone Therapy for Women Living with HIV (HoT)
REFNo: HS7391ES


1.2 Primary Objective

1.2.1 Determine the effects of HT on VMS in WLWH in the late menopausal transition or early postmenopause.

1.3 Secondary Objectives

1.3.1 Evaluate the safety and tolerability of HT as compared to placebo.

1.3.2 Determine the effect of HT on neurocognition.

1.3.3 Determine the effect of HT on mood.

1.3.4 Determine the effect of HT on sleep.

1.3.5 Determine the effect of HT on quality of life.

1.3.6 Determine the effect of HT on sexual function.

1.3.7 Determine the effect of HT on weight, waist circumference, and waist-to-hip ratio.

1.4 Exploratory Objectives

1.4.1 Determine the effect of HT on markers of bone turnover.

1.4.2 Determine the effect of HT on markers of cardiometabolic health.

1.4.3 Determine the effect of HT on systemic markers of inflammation and immune activation.

1.4.4 Determine the effect of HT on HIV reservoir size, clonality, and activity.

1.4.5 Determine the effect of HT on measures of physical function.

1.4.6 Determine the effect of HT on the rectal and vaginal microbiome.

1.4.7 Explore the effect of HT on all primary and secondary outcomes by antiretroviral regimen.

1.4.8 Explore exposure-response relationships between estradiol pharmacokinetics (PK) and study outcomes in those treated with estradiol.

1.4.9 Evaluate acceptability and feasibility of ambulatory monitors for VMS and sleep on a subset of participants.

1.4.10 Explore agreement between subjective VMS frequency with objective VMS frequency in a subset of participants.


Uganda 2026-04-24 13:20:15 2029-04-24 Medical and Health Sciences Clinical Trial Non-degree Award
Peter Olupot Simon
ID: UNCST-2025-R022744
Implementation of Sustainable Public Procurement in the Procurement of Works in Uganda’s Central Government Entities
REFNo: SS5085ES

i. To examine the relationship between external pressures and implementation of SPP.
ii. To examine the relationship between resource heterogeneity and implementation of SPP.
iii. To examine the relationship between stakeholder engagement and implementation of SPP.
iv. To examine the mediating role of resource heterogeneity in the relationship between external pressures and implementation of SPP.
v. To examine the mediating role of resource heterogeneity in the relationship between stakeholder engagement and implementation of SPP.
vi. To examine the moderating effect of procurement officers’ attitude in the relationship between resource heterogeneity and implementation of SPP.
vii. To examine how procurement officers’ attitude will moderate the relationship between external pressures and implementation of SPP through resource heterogeneity.
viii. To examine how procurement officers’ attitude moderates the relationship between stakeholder engagement and implementation of SPP through resource heterogeneity.

Uganda 2026-04-20 9:42:42 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Mboizi Baldwin
ID: UNCST-2020-R014356
Optimising Eligibility Criteria for Participant Selection in Maternal Vaccine Trials in Low-Resource Settings (ACCESS).
REFNo: HS7404ES

1. To conduct a systematic review and analyse existing eligibility criteria used in maternal vaccine trials globally, with a focus on their applicability and limitations in low-resource settings.

2. Determine the proportion of women ineligible to participate in maternal vaccine clinical trials at Kawempe National Referral Hospital using an eligibility assessment tool.

3. Determine the pregnancy outcomes in women ineligible for maternal vaccine trials at Kawempe National Referral Hospital using an eligibility assessment tool.

4. Identify factors associated with pregnancy outcomes among pregnant women excluded from trial participation.

Uganda 2026-04-20 16:50:32 2029-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yudaya Nakyeyune
ID: UNCST-2026-R024597
Using Play in Culturally Responsive Ways to Enhance Children’s Numeracy Skills Achievement in Refugee-Hosting ECD Centers in Kampala
REFNo: SS5116ES

1. To analyze children's voices of learning through play in refugee hosting ECD centers in Kampala.
2. To identify the challenges teachers encounter when using play in the teaching of numeracy in refugee hosting ECD centers in Kampala
3 To establish the impact of engagement in Continuing Professional Development (CPD) on teachers' knowledge regarding the use of play-based methods in culturally responsive ways in refugee hosting ECD centers in Kampala
4. To assess the impact of engagement in culturally responsive learning through play activities on children's numeracy achievement in refugee hosting ECD venters in Kampala
Uganda 2026-04-20 16:47:28 2029-04-20 Social Science and Humanities Clinical Trial Degree Award
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