Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Paul Okello Edward
ID:
One Health approach to identify local drivers of antimicrobial drug resistance in peri-urban Kampala, Uganda
REFNo: HS2377ES

1: Identify local drivers of antimicrobial resistance in poultry farms in Uganda through a case-control study
2a: Assess the level of antibiotic use and antibiotic resistance on a selected poultry farm by sampling litter, soil, and chicken ceca or cloaca for microbiological, analytical chemistry, and microbiome analysis.
2b: Assess the level of antibiotic use and antibiotic resistance in human populations directly exposed to poultry or poultry products from the farm.
3. Assess the level of antibiotic use and antibiotic resistance in environmental samples collected from soil, water bodies and vegetable gardens close to the poultry farm and in exposed human populations.
Uganda 2023-01-03 12:19:31 2026-01-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
An investigation of Ebola virus transmission and host immune responses among humans in Uganda
REFNo: HS2618ES

Objective 1: Characterize host immune responses to Ebola infection, therapy, and vaccination to define responses associated with protection, reduced disease, clearance of virus, and long-term post-EVD sequelae.

Objective 2: Investigate the cellular and molecular determinants of Ebola disease severity and outcome using advanced genomic studies (nascent transcriptomics)

Objective 3: Conduct seroprevalence studies to determine the burden of Ebola infection among asymptomatic contacts of EVD patients in the affected areas

Objective 4: Model periodic occurrence and transmissibility of Ebola virus within the community

Uganda 2022-12-23 18:12:56 2025-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
Understanding and Improving Antimicrobial Stewardship Among Small and Medium Sized Dairy Farmers in Uganda
REFNo: HS2607ES

1. To assess the current level of knowledge, attitudes, as well as practices among target
dairy farmers and animal health service professionals
2. To understand the barriers and enablers to implement best practices in dairy production,
with a focus on behavioural barriers.
3. To develop the Food Safety AMR training curriculum by farmers and other relevant
stakeholders.
4. To ascertain the determinants of AMR among the different dairy farms.
5. To identify behaviourally informed interventions to mitigate the barriers using enabler
analysis.
Uganda 2022-12-23 18:11:07 2025-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Monica Swahn H
ID: UNCST-2021-R012004
The Onward Project On Well-being and Adversity (“TOPOWA”): Pilot Study of Wearables
REFNo: SS1560ES

The objective of this study is to assess the feasibility and acceptability of using consumer-grade wearable wrist devices to assess sleep and activity space of adolescent girls and young women in slum communities in Kampala, Uganda. This objective will be answered through wearables wrist devices, daily diaries, focus groups discussions and a survey to collect the experiences of AGYW who are 18-24 years of age.
USA 2022-12-23 18:08:19 2025-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
Performance evaluation of the Determine™ HIV Early Detect 4th Generation HIV Rapid Diagnostic test
REFNo: HS2603ES

Primary Objectives:
1. To evaluate the Laboratory performance (Sensitivity and specificity) of the Determine™ HIV Early Detect
2. To assess the field performance of the Determine™ HIV Early Detect in parallel with the Determine™ HIV-1/2 test
Secondary Objective:
1. To assess the effectiveness of the Determine Early Detect to identify acute HIV infection among newly infected individuals

Uganda 2022-12-23 18:06:59 2025-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
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