Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,466
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ALLAN BUZIBYE
ID:
LABORATORY PREDICTORS OF DOLUTEGRAVIR-ASSOCIATED HYPERGLYCEMIA IN A COHORT OF UGANDANS LIVING WITH HIV
REFNo: HS2962ES

4 To compare mean baseline plasma levels of pro-inflammatory biomarkers/cytokines between PLHIV with and without incident hyperglycemia who are initiated on DTG.,3 To compare mean intracellular magnesium concentration between PLHIV on DTG with and without hyperglycemia.,2 To compare the mean baseline plasma levels of mitochondria dysfunction biomarkers between HIV positive patients with and without incident hyperglycemia at the time of DTG switch. ,1 To compare DTG pharmacokinetic (PK) parameters between HIV positive patients with and without incident hyperglycemia.,To investigate the mechanisms for dolutegravir-associated hyperglycaemia in a Ugandan HIV positive population.,
Uganda 2023-08-03 15:42:11 2026-08-03 Medical and Health Sciences Non-Clinical Trial Degree Award
SIMON ARUNGA
ID: UNCST-2021-R013498
PILOTING TESTING OF POINT OF CARE DIAGNOSTICS TO IMPROVE DIAGNOSIS OF MICROBIAL KERATITIS IN UGANDA.
REFNo: HS2719ES

1. Our overall aim is to improve the diagnosis of the type of MK (bacterial or fungal) at secondary-level facilities in Uganda. We will do this by comparing several novel alternative point of care diagnostic tests in a phased tertiary level and secondary level approach. 2. Assess the diagnostic performance (relative diagnostic yield, time to diagnosis, uptake, and ease of use) of the alternative point-of-care tests in three secondary units in Uganda.,1. Measure the performance (sensitivity and specificity) of these tests carried out by general ophthalmic clinic personnel, compared to a composite reference standard and the ocular microbiologist at the tertiary unit in Uganda. 3. Determine the sensitivity and specificity of several novel alternative diagnostic tests compared to a composite reference standard. Novel tests to be compared include calcofluor White + KOH, smartphone-based fluorescence microscopy, and the isothermal amplification test. The tests will be conducted by an ocular microbiologist at the tertiary unit in Uganda.
Uganda 2023-08-03 15:40:49 2026-08-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
Incidence of mortality and associated factors among TB survivors in rural Uganda.
REFNo: HS2947ES

1. To determine the incidence rate of mortality among TB survivors at Masaka Regional Referral Hospital 2. To compare the incidence of mortality among TB survivors with and without HIV coinfection at Masaka Regional Referral Hospital 3. To determine the factors associated with mortality among TB survivors at Masaka Regional Referral Hospital
Uganda 2023-08-02 18:18:03 2026-08-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gloria Abura-Meerdink Akello
ID: UNCST-2023-R007309
Project Title: A Community Engaged and Mixed Methods Approach to Exploring and Assessing Adolescent Mental Health and Psychosocial Needs for School Based Settings in Uganda
REFNo: SS1922ES

To assess the acceptability and feasibility of mental health assessment for adolescents in school-based settings in Uganda,To pilot a screening process for assessing the social determinants of health, depression and anxiety among adolescents within a school-based setting in Uganda. ,To explore adolescent mental health and psychosocial needs within low resource school-based settings in Uganda. At this stage in the research, the adolescent mental health and psychosocial needs will be generally defined as physical, social, emotional, behavioral and academic needs critical for promoting adolescent health, wellbeing and quality of life.,
Uganda 2023-08-02 18:15:57 2026-08-02 Social Science and Humanities Non-Clinical Trial Degree Award
Alain Favina
ID:
AFFILIATE STIGMA AMONG CAREGIVERS AND TREATMENT OUTCOMES AMONG PEOPLE WITH MENTAL ILLNESS IN SOUTHWESTERN UGANDA
REFNo: HS2779ES

To establish the relationship between affiliate stigma and treatment adherence and quality of life among people with mental illness in southwestern Uganda.,To determine factors associated with affiliate stigma among caregivers of people with mental illness in southwestern Uganda.,To determine the prevalence of the affiliate stigma among caregivers of people living with mental illness in Southwestern Uganda.,
Burundi 2023-07-27 21:05:27 2026-07-27 Medical and Health Sciences Non-Clinical Trial Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."