Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
A phase 2, partially-blinded, randomised trial assessing the safety and efficacy of TBAJ876 or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis
REFNo: HS2928ES

The objectives of the trial are to evaluate the efficacy, safety, and tolerability of TBAJ876 (3 doses) or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, smear-positive pulmonary DS-TB in comparison to the SOC
Uganda 2023-08-07 15:20:08 2026-08-07 Medical and Health Sciences Clinical Trial Non-degree Award
Kamada Lwere
ID: UNCST-2022-R009359
GUT MICROBIOME COMPOSITION, IMMUNE RESPONSE, AND GENETIC PREDISPOSITION TO ALZHEIMER’S DISEASE AND RELATED DEMENTIA IN A UGANDAN POPULATION.
REFNo: HS2930ES

1. To conduct a systematic review of the gut microbiome composition of individuals with Alzheimer’s disease and related dementia. 2. To determine the composition of the gut microbiome and compare individuals with ADRD and their controls. 3. To determine the levels of proinflammatory cytokines and compare individuals with ADRD and their controls. 4. To determine the distribution of ApoE (ApoE2, ApoE3 and ApoE4 variants) and ABCA7(Premature termination codon (PTC) mutations) and Presenilin (PSEN 1, 2 mutations) and compare individuals with ADRD and their controls.
Uganda 2023-08-07 15:12:16 2026-08-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Ephraim Kisangala
ID:
Preferences, value and impact of informal caregivers in the management of chronic diseases in sub-Saharan Africa (SSA)
REFNo: SS1846ES

• To examine the health and economic impact of caregiving on informal caregivers (ICGS) of patients with chronic diseases in sub-Saharan Africa • To understand the factors ICGs consider when making a decision to provide care to a person with a chronic disease in SSA. • To explore how providing informal care affects the lives of informal caregivers. • To determine the most important factors in the decision to provide informal care. • To estimate the monetary value of providing informal care to patients with chronic diseases.
Uganda 2023-08-07 15:04:16 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Shubaya Naggayi Kasule
ID:
Infections, Academic Achievement and Cognitive Functioning among Children with Sickle Cell Anaemia in Uganda.
REFNo: SS1883ES

To synthesize data on academic achievement among children with SCA in LMICs and assess academic achievement, cognitive functioning and infections among Ugandan children with SCA.
Uganda 2023-08-07 14:59:23 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Alfred Wonyaka
ID:
Eco theology: A strategy for Ecological protection in Mountain Elgon Region Church of Uganda
REFNo: SS1713ES

a). To analyze the current ecological trends in Mountain Elgon region
b.) To access the effects of current ecological trends on ecological health in Mountain Elgon region.
c.) To examine how eco theology could be utilized as a strategy for ecological protection in Mountain Elgon region.

Uganda 2023-08-07 14:56:55 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
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"A prosperous Science and Technology Led Ugandan Society."