Adoke Yeka
ID: UNCST-2021-R004300
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An adaptive, randomized, active-controlled, open-label, sequential cohort,
multicenter study to evaluate the efficacy, safety, tolerability and
pharmacokinetics of intravenous cipargamin (KAE609) in adult and pediatric
participants with severe Plasmodium falciparum malaria (KARISMA –
KAE609’s Role In Severe Malaria)
REFNo: HS1980ES
Primary objective
To assess the efficacy of different doses of
intravenous cipargamin vs artesunate by evaluating the proportion of
participants with ? 90% reduction of parasitemia at 12 hours post
administration of the first dose.
Secondary Objectives
1. To assess the presence/absence of severe malaria related individual
signs over time
2. To evaluate parasite clearance dynamics and proportion of participants
with recrudescence and reinfection
3. To assess recovery of participants as measured by time (days and hours)
to discharge from hospital or recovery from prostration
4. To evaluate the safety and tolerability of IV cipargamin
5. To assess the risk of long term neurological sequelae for participants at
Day 29
6. The assess the risk of hemolysis (early and delayed) during the study
duration
7. To characterize the plasma pharmacokinetics of IV cipargamin
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Uganda |
2023-08-18 9:05:14 |
2026-08-18 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Juliane Etima
ID: UNCST-2022-R008983
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Young Generation Alive Survey: Determining Knowledge, Aspirations, and Behaviors of Ugandan Adolescents and Young People Living with HIV.
REFNo: SS1910ES
To understand the HIV knowledge and behaviors among HIV+ and perinatally exposed adolescents and young people in Uganda with respect to achieving career aspirations, financial security, and safe intimate relationships.,
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Uganda |
2023-08-15 15:43:39 |
2026-08-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Fiona Ssozi Catherine
ID:
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PATHWAYS TO CHANGE: TOWARDS GENDER JUSTICE IN SCIENCE, ENGINEERING, TECHNOLOGY AND MATHEMATICS (STEM) RESEARCH IN AFRICA (GEJUSTA)
REFNo: SIR240ES
Primary objective: Examine causes of under-representation and reframe Gender Analysis in STEM in Africa
Secondary objectives: Map under-representation, barriers and support mechanisms; explore STEA+M approaches; Develop Gender-aware design methodologies; Develop a support network for mentoring early-career female researchers
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Uganda |
2023-08-15 15:42:06 |
2026-08-15 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
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Jesca Nantume
ID: UNCST-2021-R013984
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EVALUATING EQUITABLE ACCESS TO HEALTH SERVICES FOR SCHISTOSOMIASIS IN COMMUNITY-BASED HEALTH CENTERS; A MIXED METHODS CROSSECTIONAL STUDY IN MAYUGE AND KALUNGU DISTRICT IN UGANDA
REFNo: SS1887ES
3. To identify and understand the barriers that hinder equitable access to health services for schistosomiasis, including socio-economic factors such as income, education level, and employment status, as well as cultural beliefs, attitudes, and practices that affect healthcare-seeking behaviors.,2. To evaluate the accessibility of health services for schistosomiasis in terms of geographical proximity, transportation, cost, and waiting times for individuals seeking diagnosis, treatment, and follow-up care.,1. To assess the availability of health services for schistosomiasis in community-based health centers in Mayuge and Kalungu Districts, Uganda, including the availability of diagnostic tools, treatment options, and healthcare professionals trained in schistosomiasis management.,The main aim of the study is to assess and evaluate the level of equitable access to health services for schistosomiasis in community-based health centers in Mayuge and Kalungu Districts, Uganda, by considering various factors such as availability, accessibility, utilization, and quality of services. The objective is to gain a comprehensive understanding of the barriers and facilitators that impact equitable access to schistosomiasis healthcare services, including the influence of socio-economic factors, cultural beliefs, knowledge and awareness levels, and gender dynamics.,
|
Uganda |
2023-08-15 15:40:28 |
2026-08-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Alison Elliott
ID: UNCST-2023-R006524
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Understanding the role of, and relationship between, structural, social and biological determinants of vaccine response to improve vaccine impact in Kenya and Uganda: a formative study.
REFNo: HS2901ES
1. To conduct a scoping review exploring how social, structural and biological drivers interact to influence vaccine response.
2. To undertake formative ethnographic case studies to investigate these interactions in two communities where biological factors are known to influence vaccine response.
3. To map stakeholders and influencers critical to vaccine impact in Uganda and Kenya.
4. To work with stakeholders and communities to co-design the VAnguard community surveys to be conducted in year 2 of the programme
|
UK |
2023-08-10 15:46:52 |
2026-08-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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