Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
|
ASSESSING THE IMPACT OF STRATEGIC INITIATIVES FOR FINDING MISSING PEOPLE WITH TUBERCULOSIS IN UGANDA
REFNo: HS2945ES
This study aims to assess the impact of strategic innovations for finding and treating missing people with TB and document best practices with the aim of suggesting improvement in the design and implementation of the interventions.
The specific objective of this project are:
1. To assess the extent of implementation of the elements of the various CFIs
2. To determine the impact of implemented interventions on TB notifications and treatment outcomes in areas of implementation
3. To document best practices of implementation and challenges faced during implementation of the interventions
4. To gather views for interventions improvement from providers and receivers of the interventions
5. To estimate the costs of the implemented interventions.
6. To evaluate the cost-effectiveness of the implemented interventions.
|
Uganda |
2023-09-05 14:04:52 |
2026-09-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
MIRIAH KEMIGISHA
ID: UNCST-2022-R009927
|
When Cerebrospinal Fluid (CSF) is Unfit for Definitive Surgical Diversion: A single Institution Experience from 2001 to 2022.
REFNo: HS2927ES
1.3.1 Primary Objective
To describe the evolution of care of hydrocephalus patients with CSF unfit for definitive surgery treated at CCHU from January 2001 to December 2022.
1.3.2 Specific Objectives.
1. To describe the different temporary/non definitive forms of management of hydrocephalus when CSF is un fit for definitive surgery.
2. To describe and characterize the patient populations that benefitted from each temporary/non definitive form of management.
3. To describe the complications of each temporary/non definitive form of management of hydrocephalus when CSF is un fit for definitive surgery.
4. To evaluate the changes in brain volume in hydrocephalus patients after temporary/non definitive forms of management.
|
Uganda |
2023-09-05 14:02:43 |
2026-09-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Sentrine Nasiima
ID:
|
Prevalence and Correlates of Mental Disorders and Work Performance Among Health Care Workers in Uganda:
A Case Study from Central and South-Western
Uganda (Rescue Study)
REFNo: HS3134ES
a) To investigate the pattern, prevalence and associated factors of mental disorders/problems among health workers in public health care facilities in south-western Uganda.
b) To investigate the prevalence and risk factors (including mental disorder) and protective factors for poor work performance among health workers in public health care facilities in south-western Uganda;
c) To explore health workers’ experience of stress including work related-stress, its impact on mental health and work performance and associated coping mechanisms.
d) To explore how the COVID-19 global pandemic impacted the mental health and work
performance of health workers in health facilities in south-western Uganda and how they coped with these.
|
Uganda |
2023-09-05 14:01:30 |
2026-09-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Lian Thomas Francessca
ID: UNCST-2022-R010668
|
Baseline studies for characterising the area-specific context for the control of Taenia solium infections in northern Uganda
REFNo: A263ES
1. To estimate the prevalence of porcine cysticercosis (PCC) and pig gastrointestinal parasites in Kitgum, Lamwo, Agago, and Pader districts in northern Uganda.
2. To characterise porcine cysticercosis risk factors in the four districts to support the design of interventions.
3. To understand the socioeconomic, cultural, and policy context in which T. solium control will be undertaken in Northern Uganda.
4. To identify stakeholders their roles, relationships, power dynamics, and motivations in the control of Taenia solium infections using the net-mapping methodology.
|
UK |
2023-09-05 13:59:55 |
2026-09-05 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
|
Bacterial and Host Heterogeneity in TB latency, persistence and progression
REFNo: HS3039ES
Objective 1: Determine the extent to which household transmission is responsible for co-prevalent and incident TB cases caused by Mtb strains that are genetically distinct from those isolated from the index cases within the same household.
Objective 2: Investigate the in vitro immune phenotype of transmitted versus not-transmitted Mtb strains in households stratifying for HIV status.
Objective 3: Characterize the innate macrophage response to high and low transmission strains and the T-cell response in persons with known household exposure to high and low transmission isolates and the impact of HIV infection.
Objective 4: Identify the component of Mtb genes that aid in bacterial survival in aerosols.
Objective 5: Investigate the bacterial factors underlying divergence in the host response to high and low transmission isolates.
Objective 6: Determine the impact of Mtb strain phenotype (eg Mtb-HT v Mtb-LT) and host heterogeneity (risk of progression signatures, co-morbidities) on:
6.1. The distribution of stages of Mtb infection and disease in exposed HHC: the proportion of MTBI that express PREDICT29, a risk of progression signature; ACS-COR, an inflammatory signature; subclinical TB and active TB.
6.2. The risk and timing of progression from MTBI to TB.
6.3. The extent and nature (eg cavitation) of pulmonary disease in TB index cases; the duration of inflammation; and the consequent short- and long-term impairment in pulmonary function.
These studies could permit the development of individualized approaches based on the host and the bacterium to diagnosis, targeting of preventive therapy, and treatment of active TB.
Objective 7: Profile the lung milieu among individuals infected with either Mtb-HT or Mtb-LT in order to identify immune mediators associated with transmission heterogeneity.
|
Uganda |
2023-08-30 16:32:02 |
2026-08-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
| View |
|
Sort By: |
|
|
|
| |
|