Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Herbert Muyinda
ID: UNCST-2019-R000373
 Cango Lyec (Healing the Elephant) Study: Determining HIV Vulnerabilities and Designing Targeted Interventions to Improve Clinical outcomes among conflict affected Adolescent girls and young women under 25 in Northern Uganda
REFNo: HS521ES

1. Estimate prevalence and incidence of HIV, Hepatitis B, and syphilis, and identify associated risk factors among conflict-affected young women in Northern Uganda

2. Investigate associations between posttraumatic stress, resilience, and depression with HIV incidence among conflict-affected young women in Northern Uganda

3. Pilot feasibility and acceptability of comprehensive mHealth package to support engagement in HIV care among conflict-affected young women living with HIV in Northern Uganda

 Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Dathan  Byonanebye Mirembe
ID:
Impact of Mobile Health Interactive Software on Tuberculosis Treatment Outcomes: The Call for Life (CFLU-TB) Project
REFNo: HS524ES

To determine the effect of CFLU-TB on TB treatment success (treatment completion and cure rates) in patients with TB receiving care at three public health facilities in Uganda.
1. To compare TB cure rates (six months) in patients with microbiologically diagnosed TB in the intervention and control arms.
2. To compare treatment completion (six months) in patients clinically diagnosed with TB in the intervention and control arms.
3. To determine the effect of enhanced TB treatment support with CFLU-TB on retention at 2 and 6 months in patients receiving TB treatment at Kisenyi Health Center IV.
4. To assess perception of patients’ care providers (treatment buddies) and other stakeholders towards the CFLU-TB.
5. To determine the cost-effectiveness of the CFLU-TB intervention.
6. To compare adherence rates between patients in the intervention arm and control arms.
7. To determine the effect of CFLU-TB on adherence to clinic appointments.
8. To compare knowledge about TB/HIV in patients enrolled in the intervention and control arms.
9. To determine Drug-resistant TB rates in the intervention and control arms.
10. To determine the uptake of the CFLU-TB tool in patients and their care providers (treatment buddies).


 Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Fredrick Mutungi
ID:
CONTEXT-FITTING MOBILE SERVICES FOR MONITORING THE DELIVERY OF PUBLIC HEALTH SERVICES
REFNo: SIR20ES

1. To identify the performance indicators of mobile services for monitoring the delivery of public health services.
2. To establish the performance of existing mobile services used for monitoring the delivery of public health services.
3. To find out the contextual factors affecting the performance of mobile services for monitoring the delivery of public health services.
4. To design a model for guiding development of context-fitting mobile services for monitoring delivery of public health services.
5. To establish performance improvements anticipated with the use of context-fitting mobile services when monitoring the delivery of public health services.

 Uganda 2020-02-19 2023-02-19 Engineering and Technology Degree Award
John Mark Bwanika
ID:
Utilization Of Telehealth (Tele-care) To Improve Post-Clinic Therapy For Youths with HIV and Depression- A Feasibility Study.
REFNo: HS539ES

-Design and develop mobile/web content for post-clinic telecare for young adult HIV patients with depression.

-Assess feasibility and acceptability of the telehealth intervention Package (Telecare) for depression among HIV young adult patients as well as their post-intervention self-efficacy.

 Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Sara Weschler Weschler
ID:
Deep Roots and Bitter Greens: Legacies of Colonial-Era Forced Displacement in Western Acholiland
REFNo: SS419ES

For my Master’s thesis research I studied the way British colonial officials used Sleeping Sickness control measures to justify the forced relocation of the entire population of western Acholiland between 1911 and 1920. For my PhD dissertation research, I will use qualitative interview methods to explore how the history of this early colonial-era forced displacement is remembered and understood in Acholiland today. I intend to examine what sorts of socio-cultural changes colonial-era displacement precipitated in Acholiland. At the same time, though, I hope to trace examples of cultural resilience and examine how Acholi culture and society recovered from these upheavals over the course of the intervening century.
 USA 2020-02-19 2023-02-19 Social Science and Humanities Degree Award
Ian Munabi G
ID:
Birth related brain injury in Ugandan full term neonates
REFNo: HS551ES

Objective 1: To determine the association between foetal head moulding and hypoxic ischemic encephalopathy following spontaneous vaginal delivery.

Secondary objective:
Objective 2a: To determine the foetal factors (including foetal weight, infections, head circumference and birth order), associated with hypoxic ischemic encephalopathy following spontaneous vaginal delivery with foetal head moulding

Objective 2b: To determine the maternal factors (including maternal body mass, dietary patterns, gut microbiome, parity, social economic status and birth experience), associated with hypoxic ischemic encephalopathy following spontaneous vaginal delivery with foetal head moulding
 Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Milton Rwangire
ID:
Revitalizing Indigenous Knowledge: Integrating Indigenous Agricultural Knowledge into Modern Agricultural Practices for Sustainable Rural Household Food Security in Uganda
REFNo: SS233ES

Establish how indigenous agricultural knowledge and modern agricultural practices can be mainstreamed to enhance food security in Isingiro District 2. Analyze the existing forms and practices of modern agricultural practices and their contribution to food security in Isingiro District 3. Assess the importance of women’s secure land rights towards food security in Isingiro District 4. Establish the existing barriers to mainstreaming indigenous agricultural knowledge along modern agricultural practices in food security programmes in Isingiro District
Uganda 2020-02-11 2023-02-11 Social Science and Humanities Degree Award
Lydia Nakiyingi
ID:
Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for drug-sensitive Tuberculosis (TRUNCATE-TB)
REFNo: HS336ES

To test the hypothesis that the TRUNCATE-TB management strategy is non-inferior to the standard TB management strategy assessed by the proportion of patients with unsatisfactory outcome at 2 years (96 weeks) after randomisation.
Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Non-degree Award
Robert Kairania
ID:
HIV DISCLOSURE TRAJECTORIES AND ADHERENCE TO ANTIRETROVIRAL THERAPY AMONG CHILDREN IN MASAKA REGION, UGANDA.
REFNo: HS522ES

i. To assess the association between disclosure of HIV diagnosis and ART adherence among children on ART
ii. To examine the socio-cultural factors that influence disclosure of HIV diagnosis among children on ART
iii. To explore lived experiences before, during and after disclosure of HIV diagnosis among children on ART

 Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Degree Award
Deborah Natumanya
ID:
A framework and its algorithms towards zero pulp paper based electronic examination process
REFNo: SIR21ES

Main objective
To attain a secure and Robust Electronic Examinations assessment Process for University Students
Specific objectives
To examine the usage and security of existing modes of assessment used in universities.
To design a Framework and its supporting Algorithms for Achieving a complete electronic university students assessment process.
To evaluate the usage and security of the developed framework and its algorithms.

 Uganda 2020-02-11 2023-02-11 Engineering and Technology Degree Award
Yona Mbalibulha
ID:
Maternal Rh-Alloimmunization and Haemolytic Disease of the Newborn in South Western Uganda: alloantibodies profile and associated risk factors
REFNo: HS508ES

1. To establish the Rh antigen profile (i.e. C, c, D, E, and e antigens) among pregnant women in South Western Uganda.

2. To determine the prevalence of anti-Rh alloimmunization and the alloantibody identity among alloimmunized pregnant women in South Western Uganda.

3. To determine the anti-Rh antibody titers and the association to incidence of Hemolytic Disease Newborn in alloimmunized pregnant women

4. To identify risk factors for the presence of alloantibodies in pregnant women in south western Uganda

Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Degree Award
Kim van Dijk
ID:
Jackfruit sharing between wild chimpanzees (Pan troglodytes schweinfurthii) living in a human-dominated landscape in Bulindi, Uganda.
REFNo: NS114ES

To determine how chimpanzees share jackfruit (e.g. patterns of active versus passive sharing, begging, harassment, and theft).
To determine which factors influence jackfruit sharing (e.g. female sexual swelling, harassment, social bonding, kin relations).
To map where chimpanzees forage for jackfruits.
To determine to what extent jackfruit sharing is similar to meat sharing in other chimpanzee populations.

 Netherlands 2020-02-11 2023-02-11 Natural Sciences Degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
 Treatment Outcomes of Difficult-to-Treat Drug resistant TB Patients: A retrospective evaluation of cases reviewed by the national TB consilium in Uganda
REFNo: HS452ES

Primary Objective 1: To determine the treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consilium in Uganda

Primary Objective 2: To compare the treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consilium in Uganda with those that have not been reviewed by the DR-TB consilium in Uganda

Secondary Objective: To establish predictors of treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consolium in Uganda

 Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Judith Mutyabule NA
ID:
Exploring the influence of organisational culture: nurses' perspective on clinical leadership in a public hospital in Uganda
REFNo: HS480ES

To describe staff nurse clinical leadership
To explore the organisational culture influence on the structural environment of the staff nurses
To explain the barriers and facilitators of staff nurse clinical leadership
 Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Degree Award
Samson Okello
ID: UNCST-2019-R001580
 Cardiovascular risk factor profiles and outcomes in rural Uganda: The Bugoye Hypertension Improvement Project (B-HIP)
REFNo: HS487ES

1. To assess the baseline (at time of enrollment to BHIP) prevalence of various cardiovascular risk factors (obesity, dyslipidemia, and diabetes mellitus) in adults visiting the Bugoye Hypertension Improvement Project.
2. To determine incidence of sustained blood pressure control among persons with hypertension enrolled in BHIP.
3. To assess the costs of hypertension care in a Level III healthcare center in rural Uganda.
 Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 Pharmaceuticals in the Environment: The emerging pollutant for surface water and food stuffs grown in Kampala City, Uganda
REFNo: HS530ES

General Objective
To assess existence of the PiE phenomenon, explore factors that may be contributing to it and propose short term and long term mechanisms to mitigate it in the KCCA

Specific Aims
•To establish magnitude of PiE in the KCCA
•To establish the factors that may be contributing to the PiE in KCCA

 Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Abner Tagoola
ID: UNCST-2021-R013446
 Saving young lives: Triage and management of sepsis in children using the point-of care Paediatric Rapid Sepsis Trigger (PRST) tool
REFNo: HS528ES

The purpose of this study is to develop and implement a digital trigger tool and electronic dashboard to guide frontline health workers in triaging children at facilities in LMICs with severe infection/suspected sepsis. This is with the goal of reducing time to diagnosis and treatment of critically ill children and ultimately reducing preventable child deaths from sepsis secondary to infectious disease.
Specifically, the research seeks to develop a prediction model and to perform clinical validation of a digital trigger tool to guide triage and treatment of children at health facilities in LMICs with severe infections/suspected sepsis.

Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Menno Veen Niels Eduard
ID:
VULNERABILITY-RESILIENCE OF POTATO AND RICE FARMERS IN UGANDA TO SHOCKS: AN IMPACT ASSESSMENT OF THE INTERNATIONAL FERTILIZER DEVELOPMENT CENTERS (IFDC) REACH-UGANDA Project
REFNo: SS413ES

The objective of this study is threefold. First, to understand what are the shocks that rice and potato growing households in South-West and East Uganda are facing and what coping mechanisms households they use prior to and in response to shocks. Second, to quantify the vulnerability of households. Third, to measure the impact of the REACH-UGANDA project on households’ effectiveness of currently used coping mechanisms on well-being and the likelihood to fall into poverty.
 Netherlands 2020-02-07 2023-02-07 Social Science and Humanities Degree Award
Johanna Meinecke
ID:
Consumer acceptance of novel healthy fruit and vegetable products in East Africa
REFNo: SS418ES

Factors influencing consumers’ perception of processed fruits and vegetables
(1) Examine sensory characteristics of jackfruit juice and cowpea leaf porridge by rural and urban consumers
(2) Elicit consumers’ willingness to pay for jackfruit juice and cowpea leaf porridge
(3) Relate consumers’ dietary and purchasing behaviour to acceptance of processed fruits and vegetables
(4) Analyse if information on products nutritional value, convenience and seasonality can enhance consumers acceptance
 Germany 2020-02-07 2023-02-07 Social Science and Humanities Degree Award
Mercy Muwema
ID:
ASSESSMENT OF THE QUALITY OF PERINATAL CARE, AND DEVELOPMENT OF AN IMPROVED QUALITY OF PERINATAL CARE MODEL TO REDUCE PERINATAL DEATHS IN BUNYORO REGION
REFNo: HS483ES

Primary Objectives
1.To describe the health facility and health worker structures in place to support perinatal care at district hospitals in Bunyoro region.
2.To assess the prevalence and factors associated with poor quality of perinatal care at district hospitals in Bunyoro region
3.To assess the association between quality of perinatal care and birth outcomes at district hospitals in Bunyoro region
4.To explore care providers and client’s experiences on quality of perinatal care at district hospitals in Bunyoro region
5.To develop a context-specific quality of perinatal care model for Bunyoro region

Secondary objective
6.To assess the feasibility and acceptability of the context-specific quality of perinatal care model

Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
 DPART STUDY: DIHYDROARTEMISININ-PIPERAQUINE IN THE CONTEXT OF ANTIRETROVIRAL THERAPY
REFNo: HS486ES

OVERALL AIM: To determine the PK/PD of DP in HIV-infected children in the setting of first-line ART regimens including LPV/r, EFV and potentially the integrase inhibitor dolutegravir (DTG) which may become widely used in older Ugandan children.
Our primary objectives are:

PRIMARY OBJECTIVES:

1) To evaluate and compare the PK exposure and safety of single dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L1 vs C1)
2) To evaluate and compare the PK exposure and safety of 3-dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L3 vs C3a)
3) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on EFV-based ART and HIV-uninfected children not on ART (Group E3 vs C3a).
4) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on DTG-based ART and HIV-uninfected children not on ART (Group D3 vs C3b).

SECONDARY OBJECTIVES:

1) The effects of DP on antiretroviral PK in the above 3-dose arms (EFV, DTG, LPV/r and controls)
2) To evaluate the association of anthropomorphic indicators of malnutrition on PK exposure of DP in HIV-infected and HIV-uninfected children
3) Assess auto-induction of DHA from single dose to 3-dose
4) To assess the prevalence of pharmacogenetic variants in key metabolic enzymes, including UGT1A1, CYP2B6, CYP3A4, and ABCB1, and the impact of these variants on ACT and ART PK.


 Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
 Prevalence of multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences
REFNo: HS491ES

1. To determine the prevalence of multidrug resistant bacteria on mobile phones of final year medical students at Makerere University College of Health Sciences.
2. To determine risk factors associated with multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences

 Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Ryoma OTSUKA
ID:
Study on Sustainability of Mountain Gorilla Tourism: From a Tourism Management Perspectives
REFNo: SS387ES

The aim of this study is to contribute to the sustainable development of mountain gorilla tourism in Uganda. We have three main objectives of our study. The first one is to better understand tourist needs or expectations and how it is engendered in relation to information sources. The second one is to better understand and explore factors that affect tourist satisfaction. The third one is to understand rangers’ perception of mountain gorillas, gorilla tourism, and tourists.
 Japan 2020-02-06 2023-02-06 Social Science and Humanities Degree Award
Amy Young
ID:
Causes of under-five child mortality in the slum communities of Kampala, Uganda: A Verbal and Social Autopsy Study
REFNo: HS507ES

The study seeks to identify the biomedical causes of death as well as the sociodemographic, behavioral and environmental factors associated with child mortality in the slum communities of Kampala. This includes recognition of illness, decisions around care-seeking, and care-seeking behaviors.
USA 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Othman Kakaire
ID: UNCST-2019-R000359
 A randomized controlled trial of copper and levonorgestrel intrauterine contraceptive devices among postpartum women in Uganda.
REFNo: HS337ES

Primary Objective:
1)To determine if there is a difference in expulsion rates at twelve months in women randomized to have the Levonorgestrel or copper intrauterine devices inserted in the immediate postpartum period (defined as after delivery of placenta to 48 hours postpartum).
Secondary objectives:
1.To explore women’s perceptions of postpartum contraception
2.To compare discontinuation rates of LNG-IUS and Copper IUD at 12 months
3.To compare pregnancy rates between the two arms at 12 months
4.To compare patterns of vaginal bleeding between the two arms
5.To compare contraceptive satisfaction between the two arms at 3, 6 and 12 months
6.To compare time from delivery to lactogenesis between the two arms
7.To compare breastfeeding over the initial 6 months between the two arms
8.To compare the change in infant weight, length and head circumference from delivery to 6 weeks and from delivery to 6 months between the two arms
9.To compare adverse events including but not limited to uterine perforation, pelvic infection, IUC expulsion, thromboembolism, and death between the two arms

 Uganda 2020-01-29 2023-01-29 Medical and Health Sciences Non-degree Award
Abubakar Mustafa Sadik
ID:
Mechanisms of defense against Xanthomonas campestris pv. musaceurum infection in banana cultivars
REFNo: NS107ES

1. To determine whether callose induction is an effective measurable defense output in banana immune response to Xcm infection.

2. To identify the differentially regulated genes during Xcm-banana interaction.

3. To identify differentially regulated metabolites during Xcm-banana interaction.

4. To determine the spatial-temporal distribution of Xcm in banana tissues
Uganda 2020-01-21 2023-01-21 Natural Sciences Degree Award
Joseph Rwothumio
ID:
RELATIONSHIP BETWEEN HUMAN RESOURCE MANAGEMENT PRACTICES AND ACADEMIC STAFF PERFORMANCE IN SELECTED PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS400ES

This study endeavored to:
1.Establish the relationship between training and academic staff teaching output in selected public universities in Uganda.
2.Establish the relationship between training and academic staff research output in selected public universities in Uganda.
3.Examine the relationship between financial reward and academic staff teaching output in selected public universities in Uganda.
4.Examine the relationship between financial reward and academic staff research output in selected public universities in Uganda.
5.Determine the relationship between performance appraisal and academic staff teaching output in selected public universities in Uganda.
6.Determine the relationship between performance appraisal and academic staff research output in selected public universities in Uganda.

 Uganda 2020-01-21 2023-01-21 Social Science and Humanities Degree Award
Nicholas  Penny Gordon
ID:
Conserving the Gorillas of Bwindi
REFNo: NS111ES

The objectives of this project are: - to create a complete photo-story and short film about the work of UWA, CTPH and local communities around Bwindi. This will include gorilla treks, the process of finding the gorillas, sample collections from gorilla night nests, how samples are used/analyzed to determine the health of the individuals within a troop and the work in the CTPH Gorilla Health and Community Conservation Center. - to support UWA and CTPH by giving all photographs and the completed film to them free of charge at the end of the research period; - to celebrate Uganda’s commitment and role at the forefront of gorilla conservation; - to support UWA and CTPH and promote the work they do, showing the care and dedication of people who work directly with the gorillas and local people.
UK 2020-01-21 2023-01-21 Natural Sciences Degree Award
Benson Oloya
ID:
Phytochemistry, Antitubercular activity and Cytotoxicity of Selected Plant Species used for the Treatment of Tuberculosis in Uganda
REFNo: NS112ES

i. To isolate and carry out structure determination of the compounds from the four plant species selected,
ii. To investigate the antitubercular activity of the crude extracts and compounds from the four plant species selected,
iii. To determine the cytotoxicity of the crude extracts

 Uganda 2020-01-21 2023-01-21 Natural Sciences Degree Award
FAITH NATUKUNDA
ID:
Optimisation of Thermal and Power Requirements of Resistive Coil-based Low Field MRI Systems
REFNo: SIR24ES

1. Examine the methods of cooling that have been applied in thermal management of resistive coil systems
2. Examine the power and thermal limits of Low field MRI systems
3. Design and numerically analyze a cooling system for a low field MRI system
4. Validate numerical results using experimental data
 Uganda 2020-01-21 2023-01-21 Engineering and Technology Degree Award
Kamada Lwere
ID: UNCST-2022-R009359
 Diversity of Gut Microbiome in Azheimers disease and related dementia in Ugandan Patients
REFNo: MHS2ES

1.To describe the variation in gut microbiome among individuals with Alzheimer’s disease and related dementia.
2.To determine factor association with gut microbiome changes in individuals with Alzheimer’s and related dementia.

 Uganda 2020-01-13 2023-01-13 Medical and Health Sciences Non-degree Award
Martin Kyamanywa Martin
ID:
The East African political Federation Dream: Exploring the Missing Link(s)
REFNo: SS403ES


i). To examine the measures put in place to fast track the East African Federation dream
ii). To explore the anticipated benefits of the East African political Federation to the people of the region.
iii). To establish the key factors favoring the creation of the East African Federation
iv). To identify factors that may hamper attaining the East African political Federation dream

2020-01-13 2023-01-13 Social Science and Humanities Degree Award
Joseph Matovu
ID:
Repeat Survey and Mid-Term Evaluation of the Global Fund-Supported Adolescent Girls and Young Women Project
REFNo: SS411ES

a) To determine the extent to which the project is on target to achieve set objectives and explore potential options for improving project implementation in the remaining period leading to project completion
b) Assess the adequacy of the TASO-AGYW project coordination mechanisms and management structure in supporting the implementation of the project by sub-grantees
c) Document the key strategies/innovations used by sub-grantees to address the needs and vulnerabilities of AGYW and establish the extent to which they meet the needs of AGYW as identified at baseline
d) To establish if the period of implementation has yielded value for money/efficiency
e) To document and compare success stories and lessons learned in implementing AGYW interventions in DREAMS and Global Fund supported AGYW districts
f) To monitor campaign implementation and take stock of the challenges experienced in the implementation of AGYW interventions, and seek suggestions from implementers and key stakeholders as to how best these challenges can be minimized

 Uganda 2020-01-13 2023-01-13 Social Science and Humanities Non-degree Award
Ambrose Murangira
ID:
Disability and Communication Technologies: Access to HIV and AIDS Education Messages Among Deaf Persons in Uganda
REFNo: HS478ES

The general objective is to examine how health communication technologies influence access to HIV and AIDs Education Messages by Deaf persons and (re) shape their preventive and treatment seeking practices.

Specific Objectives:

To identify the various forms of communication technologies through which Deaf persons receive HIV/AIDs education messages.

To establish how different forms of communication technologies influence (either facilitate or inhibit) access of HIV/AIDS education messages by Deaf persons

To examine how communication technologies (re)shape the HIV&AIDS preventive and treatment seeking practices of Deaf persons

To examine the role and contribution of organizations/institutions in facilitating/inhibiting access to communication technologies by Deaf persons

 Uganda 2020-01-13 2023-01-13 Medical and Health Sciences Degree Award
Emmanuel Ahishakiye
ID:
A Dictionary Learning Approach for Medical Image Reconstruction in Low Field Magnetic Resonance Imaging
REFNo: SIR23ES

i. To determine the suitable dictionary learning algorithms for image reconstruction in low field MRI.
ii. To design and develop a suitable algorithms capable of image reconstruction in low field MRI.
iii. To test and validate the developed algorithms as a means of demonstrating its mechanism and viability.

 Uganda 2020-01-13 2023-01-13 Engineering and Technology Degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 A PILOT STUDY TO ASSESS THE ACCEPTABILITY AND PERFORMANCE OF THE MATERNAL PPH WRAP DEVICE FOR CONTROLLING POST-PARTUM HAEMORRHAGE
REFNo: HS499ES

1. To evaluate the acceptability and usability of the Maternal PPH Wrap among health women who are not at risk of PPH

2. To evaluate the preliminary performance of the Maternal PPH Wrap on women with mild postpartum haemorrhage
 Uganda 2020-01-13 2023-01-13 Medical and Health Sciences Non-degree Award
Hannington Oryem-Origa
ID:
Developing a microbial-based product for remediation of oil-contaminated soils in Uganda
REFNo: NS108ES

i. To assess the impact of oil spillage on physical-chemical and microbial quality of soil.

ii. To isolate and characterize bacteria and fungi from oil-contaminated soil from selected sites in Uganda.

iii. To assess the oil degradation efficiency of selected bacterial and fungal species isolated from oil-polluted soils.

 Uganda 2020-01-13 2023-01-13 Natural Sciences Non-degree Award
Valerie de Koeijer
ID:
The Ethics of Preparedness in Humanitarian Disaster
REFNo: SS395ES

The objectives of the project, organized per research question, are as follows: Research question 1: How are journalists, and academics working in or adjacent to war zones trained for these conditions?

Objective: To generate knowledge about conflict-adjacent professionals’ background and training.

Research question 2: How do practitioners across professions cope with emergent ethical challenges in the everyday course of their work? Objectives: First, identify and better understand the common, everyday issues that conflict-adjacent professionals face in the line of their work. Second, to understand the way that conflict-adjacent professionals make decisions in the face of everyday challenges. Third, to gain those professionals’ own reflections on their approaches to resolving those problems. Research question 3: Do professionals’ protocols and practices evolve in the field, and if so, how?

Objective: To identify and better understand whether and how professionals’ protocols and practices evolve in the field in response to the challenges they face. This project will produce both academic and policy/practice outputs.
Netherlands 2020-01-13 2023-01-13 Social Science and Humanities Degree Award
George Matovu
ID:
FINANCIAL INCLUSION THROUGH SAVINGS AND CREDIT CO-OPERATIVES FOR INCLUSIVE GROWTH IN UGANDA
REFNo: SS409ES

This study is to investigate and understand how financial inclusion through SACCOs can be an effective option for inclusive growth in Uganda. In order to focus on the research problem and provide answers to the research questions, these specific objectives have been identified to guide, and achieve the overall aim of the study:

1.Identify and analyse the socio-economic success factors and barriers affecting SACCOs in deepening financial inclusion to enhance inclusive growth.
2.Understand the role of SACCOs in deepening financial inclusion.
3.Examine the role of financial inclusion in achieving inclusive growth

 Uganda 2020-01-13 2023-01-13 Social Science and Humanities Degree Award
Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
 Improving Glycaemic Control for Children and Young People with Type 1 Diabetes in Uganda: Towards a Feasible and Acceptable Self-Care Programme
REFNo: HS519ES

Aims of the Study
The aims of the study are to investigate factors associated with poor glycaemic control of children and young people with T1D attending the CDiC Clinics in Uganda; and to develop and evaluate an individually tailored, age-appropriate management intervention to support decision-making and self-care with a specific focus on insulin management and blood glucose monitoring with available resources. It is an implementation research.
Objectives
This is an implementation research employing a mixed methods research design. In-depth interviews will be conducted alongside unmet needs in managing the diabetes and an assessment of healthcare preferences. Because people often have diverse preferences for healthcare interventions, and preferences tend to change through the course of an illness, we shall also examine whether these preferences are characterized by heterogeneity, and if so, the extent to which this heterogeneity could be explained by relevant characteristics of people with T1D. The study will therefore have the following specific objectives:
1. To determine the prevalence of poor glycaemic control among children and young people with T1D attending CDiC clinics in Uganda.
2. To assess patient factors associated with poor glycaemic control in children and young people with T1D attending CDiC clinics in Uganda.
3. To assess family factors associated with poor glycaemic control in children and young people with T1D attending CDiC clinics in Uganda.
4. To assess health system factors associated with poor glycaemic control among children and young people with T1DM attending CDiC clinics in Uganda.
5. To assess social factors associated with poor glycaemic control in children and young people with T1D attending CDiC clinics in Uganda.
6. To determine the un-met needs in the children and young people with T1D attending the CDiC clinics in Uganda.
7. To assess diabetes care preferences in children and young people with T1D attending the CDiC Clinics in Uganda.
8. To examine whether the diabetes care preferences among T1D are characterized by heterogeneity, and if so the extent to which the heterogeneity could be explained by relevant characteristics of people with T1D or their care givers.
9 To develop a feasible and acceptable self-management intervention.
10. To assess the impact of the individually tailored age-appropriate management intervention T1D treatment on the glycaemic control (HbA1c), in children and young people with T1D attending the CDiC Clinics in Uganda.
11. To determine the frequency of hypoglycaemic episodes with the new self-management program.
12. To assess the effect of the new self-management program on the health-related quality of life (HRQoL) of children and young people with T1D.
 Uganda 2020-01-13 2023-01-13 Medical and Health Sciences Non-degree Award
Amanda Nambozo Martha
ID:
TEMPORAL VARIATIONS, ABUNDANCE AND POPULATION CHARACTERISTICS OF FISH SPECIES IN THE CATCHES OF LIGHT ATTRACTION FISHERY OF LAKE ALBERT, UGANDA
REFNo: NS113ES

General objective
To assess the temporal variations, abundance and population characteristics of dominant fish species in the catches of light attraction fishery in Lake Albert, Uganda Specific objectives
i)To establish the compositions and abundance of fish species in light attraction fishery in the three study sites over a period of one year.
ii)To determine the variation in composition of fish species in the catches over months and seasons of the year.
iii)To establish the trends in population characteristics of the dominant fish species in the light attraction fishery at three study sites over the study period. The population characteristics include;
a)Growth parameters; length, weight, length-weight relationship and recruitment
b)Sex determination, sexual maturity and size at first maturity
c)Breeding periodicity
d)Condition factor
e)Fecundity
iv)To determine the effects of light attraction fishery on its stocks and the stocks of non-target species in the catches.
v)To determine the fishers’ perception towards the exploitation of light attraction fishery of L. Albert.

 Uganda 2020-01-13 2023-01-13 Natural Sciences Degree Award
AMBROSE KIBUUKA BANYENZAKI
ID:
PARENT -TEACHER INTERFACE AND STUDENTS’ LEARNING ACHIEVEMENTS IN RURAL UNIVERSAL SECONDARY EDUCATION SCHOOLS IN SOUTH-WESTERN UGANDA
REFNo: SS373ES

Purpose of the study

The main purpose of the study will be to establish the relationship between parent teacher interface and student learning achievement moderated by parent teacher relationship and parent teacher involvement with specific reference to Universal secondary education. The study will seek to contribute to knowledge by advancing a workable model for parent teacher interface and student learning achievement.

Specific Objectives of the study

The specific objectives of the study will be:-

To analyse the relationship between parent teacher interface and parent teacher relationship

To examine the relationship between parent teacher relationship and parental involvement

To assess the effect of parental involvement on student learning achievement

 Uganda 2020-01-07 2023-01-07 Social Science and Humanities Degree Award
Saul Muyiggwa Mubanda
ID:
Professional Development Practices in Public Universities and Organizational Commitment of Academic Staff: A Case of Makerere and Kyambogo Universities in Uganda
REFNo: SS342ES

Objectives of the research project:

i. To establish the extent to which informal learning opportunities influence organizational commitment of academic staff in Makerere and Kyambogo Universities.

ii. To establish the extent to which formal training opportunities influence organizational commitment of academic staff in Makerere and Kyambogo Universities.

iii. To ascertain the extent to which staff promotions influence organizational commitment of academic staff in Makerere and Kyambogo Universities.

 Uganda 2019-12-27 2022-12-27 Social Science and Humanities Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Predicting and Preventing Tuberculosis Treatment Failure in an Emerging Co-Epidemic of HIV, Diabetes, and Tuberculosis
REFNo: HS496ES

Primary Objective:
To determine the optimal glucose screening algorithm in a high HIV-TB-burden setting and adapt an evidence-based strategy for implementing TB-DM screening, monitoring, and counseling.

Secondary Objectives:
1. To determine the effect of glucose exposure over course of treatment on adverse TB treatment outcomes.
2. To adapt, pilot, and evaluate an evidence-based complex intervention to screen, monitor, and counsel for TB-DM.

Uganda 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Impact of TB and HIV co-infection on host and microbial gene expression in the upper airway
REFNo: HS502ES

Objectives of the research project: Aim 1: Compare the differences in the microbiota and host gene expression in the upper airway of TB/HIV cases versus HIV only individuals. We will use RNA-seq to profile host gene expression and microbial abundance in TB/HIV and HIV only individuals and identify differences between these two groups.

Aim 2: Develop candidate diagnostic biomarkers for identifying TB/HIV co-infection. We will develop a preliminary nasal biomarker for differentiating TB/HIV from HIV only (controls) using host gene expression, the microbiome, or a combination.

Uganda 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Gorrette Nalwadda Kayondo
ID:
Analysis of Quality of Child Immunization Delivery in Rural and Urban Health Care Settings in Uganda
REFNo: HS505ES

a) Design short formatted and de-identified video footage for education, communication and research purpose on immunization delivery in low income settings, based on video footage previously collected under the “Child Immunization Delivery Project, Pathway/Landscape Analysis in Rural and Urban Health Care Settings in Uganda” (Protocol 258).
b)Design and develop a website/web portal to make available video, artefacts, field observation notes and other research data (de-identified data) for non-restricted use, and restricted use (raw data) to people working in public health, innovators, programmers, policy makers.
c) Explore and analyze the quality of child immunization service delivery and compliance with immunization guidelines in rural and urban health care settings, and possible solutions
d) Engaging policy makers in the use of the research findings from the child immunization delivery project for sound development of policies and programs
e) Utilize the de-identified ethno videography data for capacity building, communication and charitable global health activities in maternal newborn and child health policy development and program implementation.

 Uganda 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Cara Ebert
ID:
Impact evaluation of two youth skill development interventions as part of the Employment for Development (E4D) program of the German Corporation for International Cooperation (GIZ)
REFNo: SS397ES

The objective of the investigation is to identify interventions implemented by the German Development Corporation program E4D/SOGA that work and have the potential to be scaled up. The E4D/SOGA funds and implements a large portfolio of interventions in Uganda – comprising a total budget of EUR 10,700,000. In this light, we intend to evaluate the effectiveness of two E4D/SOGA programs. The investigation will give guidance on policy decisions by highlighting the relevance of short-course technical skills trainings, work readiness skills and labor market attachment via internship placement.
 Germany 2019-12-27 2022-12-27 Social Science and Humanities Non-degree Award
Shevin  Jacob Thomas
ID:
THE AFRICAN RESEARCH COLLABORATION ON SEPSIS IN UGANDA (ARCS-UGANDA) COHORT STUDY: AN OBSERVATIONAL STUDY TO IMPROVE UNDERSTANDING OF SEPSIS EPIDEMIOLOGY, DEFINITIONS, HOST IMMUNE RESPONSE AND COSTS OF HOSPITAL CARE IN UGANDAN ADULTS
REFNo: HS511ES

General Objective:
To describe adult sepsis prevalence and incidence, validate sepsis definitions, characterize AMR, describe short- and long- term morbidity and mortality, identify host response to sepsis and quantify hospital costs using a cohort of adult patients with suspected sepsis admitted to hospitals in Uganda

Specific objectives:
1. Determine the epidemiologic characteristics, AMR characteristics, clinical outcomes (including morbidity, mortality and frequency of readmission after discharge from the hospital) and attributable costs from suspected sepsis in Ugandan hospitals
2. Evaluate performance characteristics of extant sepsis definitions/criteria when applied to a cohort of adult patients who fulfil study eligibility criteria for sepsis in Uganda
3. Characterize pathways of sepsis pathogenesis through exemplar pro-inflammatory (through neutrophil respiratory burst activity) and immunosuppressive (through HLA-DR) markers and agnostic transcriptomic analysis in a Ugandan sepsis cohort with a high prevalence of HIV infection.

USA 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Prospective Multicentre Evaluation of the Accuracy and Diagnostic Yield of the Fujifilm SILVAMP TB LAM Test for the Diagnosis of Tuberculosis in People Living with HIV
REFNo: HS513ES

ï‚· To determine the diagnostic accuracy of FujiLAM for TB detection among PLHIV using an eMRS
ï‚· To determine the diagnostic accuracy of FujiLAM for TB detection among PLHIV using a CRS ï‚· To determine the diagnostic yield of FujiLAM among all patients identified as having TB by
eMRS and compare to AlereLAM, Smear and Xpert/Ultra (sputum, urine) as comparators
(on Day 1 specimens).

Secondary,
ï‚· To determine the diagnostic accuracy of FujiLAM for TB detection among PLHIV using a MRS.
ï‚· To determine the diagnostic yield of FujiLAM among all patients identified by MRS and compare to AlereLAM, Smear and Xpert/Ultra (sputum, urine) as comparators (on Day 1 specimens).
ï‚· To determine the diagnostic accuracy of FujiLAM across predefined subgroups using a MRS, eMRS and CRS separately.
ï‚· To determine the diagnostic accuracy of FujiLAM of Day 2 early morning urine using a MRS, eMRS and CRS separately.
ï‚· To determine the diagnostic accuracy of FujiLAM of Day 2 early morning urine across subgroups using a MRS, eMRS and CRS separately.
ï‚· To determine the diagnostic accuracy of AlereLAM in the same way as described in objectives 1.1, 1.2 and 2.1, 2.3 and compare it to that of FujiLAM.
ï‚· To determine the yield of FujiLAM over (incremental yield) or in combination with (combined yield) Smear and Xpert/Ultra (sputum) among eMRS-positive patients.
 To determine the diagnostic accuracy of Omega VISITECT® CD4 test for detection of a CD4 count ≤200 cells/µl, using WHO pre-qualified cytometers as the reference standard.  To collect and store high quality and well-characterized urine specimen from PLHIV
Uganda 2019-12-27 2022-12-27 Medical and Health Sciences Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
 Prevalence of Sputum Positive Tuberculosis and associated Factors among Individuals found at Bars in Kampala Slums
REFNo: HS459ES

Primary Objective: To determine the prevalence of sputum positive TB among individuals found at bars in Kampala slums
Secondary Objectives:
1. To evaluate factors associated with sputum positive TB individuals found at bars in Kampala slums.
2. To determine the prevalence of HIV infection among individuals found at bars in Kampala slums
3. To determine the prevalence of TB/HIV co-infection among individuals at bars in Kampala Slums

 Uganda 2019-12-13 2022-12-13 Medical and Health Sciences Non-degree Award
Jayne Webster
ID:
Process Evaluation of Integrated Immunisation & Family Planning Projects in Benin, Kenya, Malawi and Uganda
REFNo: SS367ES

1. Assess FP method acceptance and continuation in women who access immunisation and/or family planning services 2. Test associations between FP method acceptance and continuation and integration attributes 3. Assess the quality and responsiveness of integrated immunisation and FP delivery 4. Determine implementation fidelity, causal mechanisms and context in integrated immunisation and family planning 5. Develop an overall programme theory of what works, for who, how and in what circumstances the integrated delivery of immunisation and family planning
 UK 2019-12-13 2022-12-13 Social Science and Humanities Non-degree Award
Namara  Khadija Asiimwe
ID:
INFORMATION TECHNOLOGY ALIGNMENT AND ORGANIZATIONAL PERFORMANCE IN THE SERVICE SECTOR IN UGANDA. A CASE STUDY OF UMEME (U) LIMITED
REFNo: SS378ES

i.To establish the relationship between IT governance and organizational performance in Umeme Limited
ii.To establish the relationship between IT investment and organizational performance at Umeme Limited.
iii.Assess the effect IT implementation has on organizational performance at Umeme Limited.

 Uganda 2019-12-13 2022-12-13 Social Science and Humanities Degree Award
Shevin  Jacob Thomas
ID:
STUDY OF WASH AND ANTIMICROBIAL RESISTANCE IN UGANDA (SWAR-U)
REFNo: HS489ES

Primary objective: To describe the transmission dynamics and ecological niches of ESBL-E and ESBL-K within selected households from Kampala and Hoima

Secondary objectives:
To evaluate the drivers of Water, Sanitation, and Hygiene (WASH) practices and their relation to the faecal-oral transmission of extended spectrum beta-lactamase producing Eschericia coli and Klebsiella pneumoniae

To create a dynamic agent-based model to evaluate the drivers of antimicrobial resistance transmission in Uganda, through the incorporation of microbiological resistance data (ESBL-E and ESBL-K) and WASH observational data obtained from all households included in the SWAR-U study

 USA 2019-12-13 2022-12-13 Medical and Health Sciences Non-degree Award
Innocent Ssemanda
ID:
IMPLEMENTATION FIDELITY OF TRICHIASIS SURGERY PROGRAME IN NORTHEASTERN UGANDA
REFNo: HS497ES

To assess and describe implementation fidelity of Trichiasis surgery programme and associated factors, to outcomes in Northeastern Uganda.
 Uganda 2019-12-13 2022-12-13 Medical and Health Sciences Degree Award
Simon L'Allier
ID:
Behavioral endocrinology of male dispersal in vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo, Uganda
REFNo: NS84ES

Evolutionary causes and consequences (or the “why”) of dispersal are fairly well established, bein respectively inbreeding avoidance and increased reproductive success (Bowler & Benton, 2005). However, the environmental, social, individual, and physiological proximate mechanisms underlying individual dispersal decisions, and their consequences, are still poorly understood. Previous studies have mainly focused on the individual’s physiological response to
8

dispersal events (before and after) and looked at the social outcome (e.g., dominance rank) rather than the processes leading to that outcome. For this research, my objectives are to examine how the numerous potential costs of dispersal drive individual dispersal decisions as to when, where, and how they transfer (lone or parallel). I will assess the environmental, social, and physiological causes and consequences of dispersal in vervet monkeys at Lake Nabugabo. My hypotheses and predictions are summarized in Table 2. Dominance rank is often established once a male immigrates into another group. The males’ ability to take over a group and the attainment of a high dominance rank might be dependent on when, where, and how they disperse. My research contributes to a broader understanding of how the immediate environmental, social, and individual factors affect the way they transfer.
Canada 2019-12-12 2022-12-12 Natural Sciences Degree Award
Eliab Kweyunga Horub
ID:
Mathematical Models for the dynamics of banana xanthomonas wilt and the banana weevil, Cosmopolites Sordidus, (Germar) and control Interventions
REFNo: A58ES

1. to quantify the role of symptomless but infectious plants in the persistence of banana xanthomonas wilt;

2. evaluate the effectiveness of existing control options against the banana weevil;

3. use optimal control theories to originate a combination of controls that will ensure management of the pest and disease at minimal cost in terms of time, funds and environmental damage;
 Uganda 2019-12-09 2022-12-09 Agricultural Sciences Degree Award
Sarah Lofgren
ID: UNCST-2019-R001647
 The Growth Study- Group Therapy In HIV For Depression In Uganda
REFNo: HS493ES

Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
 USA 2019-12-09 2022-12-09 Medical and Health Sciences Non-degree Award
David Lawrence S
ID:
THE LIVED EXPERIENCE OF PARTICIPANTS IN AN AFRICAN RANDOMISED TRIAL (LEOPARD)
REFNo: SS386ES

AIM: To document the AMBITION participant experience in order to build an understanding of how to improve trial delivery for future participants in the trial. OBJECTIVES From the perspective of the participant: 1. To build an understanding of the factors that enhance or diminish a clinical trial experience. From the perspective of the next-of-kin of a participant: 2. To build an understanding of the factors that enhance or diminish a clinical trial experience. From the perspective of the researcher: 3. To build an understanding of the factors that are perceived to enhance or diminish a trial participant’s experience of a clinical trial. 4. To compare the individual researcher’s experience of the conceptualisation, development, initiation and implementation of a multi-centred clinical trial in Africa.
 UK 2019-12-09 2022-12-09 Social Science and Humanities Degree Award
SIMON BYONANUWE
ID:
“Prevalence, bacterial pathogens and factors associated with premature rupture of membranes at Kampala International University Teaching Hospital”.
REFNo: HS503ES

Main objective: To determine the prevalence, bacterial pathogens and factors associated with premature rupture of membranes at Kampala International University Teaching Hospital.

Specific objectives:
1. To determine the prevalence of premature rupture of membranes at Kampala International University Teaching Hospital.
2. To determine the obstetric and gynaecologic factors associated with premature rupture of membranes at Kampala International University Teaching Hospital.
3. To identify bacterial pathogens commonly associated with premature rupture of membranes at Kampala International University Teaching Hospital.
4. To assess antibacterial susceptibility patterns of the isolated bacterial pathogens.


 Uganda 2019-12-09 2022-12-09 Medical and Health Sciences Degree Award
PETER SPENCER SIMNER
ID:
Etiology of Nodding Syndrome: an Epileptic Disorder of East African Children
REFNo: HS410ES

Increase understanding of the role of environmental exposures, notably to specific neurotropic viruses, as risk factors for Nodding syndrome.
 USA 2019-12-04 2022-12-04 Medical and Health Sciences Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 PERFORMANCE OF ALTERNATIVE MEASURES OF RESPONSE TO THERAPY DURING THE INITIAL 12 WEEKS OF MDR-TB TREATMENT
REFNo: HS471ES

1. To examine the correlations of FDA smear microscopy, PMA-Xpert Ct value &16s rRNA (MBLA) with MGIT-TTP as a reference standard.
2. To evaluate the ability of FDA smear microscopy, PMA-Xpert Ct value, MBLA in predicting 12-weeks MGIT culture conversion (outcome).
3. To evaluate the influence of patient clinical characteristics, baseline resistance profiles, adherence and HIV-status to the performance of the alternative measures of response.

 Uganda 2019-12-04 2022-12-04 Medical and Health Sciences Degree Award
Jimmy Otim
ID:
Bridewealth and the Future of Customary Marriages in postwar Acholi society
REFNo: SS377ES

To examine the cultural relevance of bride wealth practices in shaping customary marriages across generations in Acholi society
To find out the changes which have occurred overtime to bride wealth practices in shaping customary marriages
To investigate how marriages are contracted in the face of scarcity of cattle and increasing bride wealth payments in postwar Acholi society
To explore perceptions and attitudes of men and women towards bridewealth practices, cohabitation, and children born out of wedlock
 Uganda 2019-12-04 2022-12-04 Social Science and Humanities Degree Award
Gerardo Zarazua de Rubens
ID:
Cleaning the air through cooking: providing alternative energy solutions for cooking practices in the Bidibidi Refugee Settlement in Yumbe district in Uganda
REFNo: SS390ES

The project focuses on investigating emissions and respiratory impact between traditional fuel burning cooking methods (solid biomass/ charcoal/ firewood) and solar voltaic clean cooking methods within the Bidibidi Refugee Settlement in northern Uganda. The aim is to evaluate the type and level of impact of each technology, in particular the effects on the environment in the form of air pollution and impacts such as deforestation, wellbeing (health and economic creation) and safeguarding.
Mexico 2019-12-04 2022-12-04 Social Science and Humanities Non-degree Award
Peter Kirabira Simon
ID: UNCST-2020-R014690
 Active Reporting of Adverse drug reactions of antiretroviral drugs among adults living with HIV in East Africa: a pilot study on using SMS
REFNo: HS431ES

2. Objectives 2.1 Main objective: To test the feasibility and acceptability of Mhealth system to create awareness on importance of reporting adverse drug reactions of antiretroviral therapy among adults living with HIV in Tanzania and Uganda
2.2 Specific objectives
1. To investigate feasibility of the SMS system among health care workers by measuring practicality, actual fit, utility, trialability,
2. To investigate acceptability of the system among health care workers by measuring and comfort, relative advantage and credibility
3. To investigate feasibility of the system among PLHIV by measuring practicality, actual fit utility, trialability.
4. To investigate acceptability of the system among PLHIV by measuring comfort, relative advantage and credibility.
5. To describe the perceptions/attitudes of HCWs towards the use of m-health to improve ADR reporting.
6. To investigate the technical feasibility of the system by measuring sent, received and replied messages.
7. To give an overview of reported ADRs among adults living with HIV in KCMC and Majengo in Moshi and Nsambya in Kampala

 Uganda 2019-11-27 2022-11-27 Medical and Health Sciences Non-degree Award
Assumpta  Barigye
ID:
Records Management Practices and Administrative Staff Performance in Private Universities in Uganda: A case of Nkumba University and Uganda Christian University
REFNo: SS370ES

1. to examine how Records Management Practices impact on Administrative Staff Performance in NU and UCU

2. to establish how Records Creation contributes to Administrative Staff Performance in NU and UCU

3. to determine how Records Maintenance ensures Administrative Staff Performance in NU and UCU

4. to access the extent to which Records Disposal Contributes to Administrative Staff performance in NU and UCU

5. to analyze the extent to which Reward Management moderates the relationship between Records Management Practices and Administrative Staff Performance in NU and UCU

 Uganda 2019-11-27 2022-11-27 Social Science and Humanities Degree Award
Mukisa Ayub
ID:
Gender and adaptive capacity to climate change among small holder farmers in Karamoja sub region
REFNo: SS379ES

i) To evaluate the effects of drought on crops and livestock for men and women in Nabilatuk District
(ii) To establish the resources for men and women in crop and livestock farming
(iii) To assess infrastructure and technological capacities of men and women in livestock and crop farming.
(iv) To identify governance, institution, and networks for men and women in crop and livestock farming.
v) To find out adaptation/resilience practices for men and women in crops and livestock farming

 Uganda 2019-11-27 2022-11-27 Social Science and Humanities Degree Award
Denish Calmax Angol
ID:
Antibacterial Use and Resistance in Under Five Children in Post Conflict Northern Uganda
REFNo: HS362ES

General study objective
•To assess the burden, drivers of inappropriate antibacterial prescriptions and resistance patterns of the pathogens among under five children attending care in selected public health facilities in Lango sub-region, northern Uganda.
Specific objectives
•To determine microbiologically, the burden and drivers of inappropriate prescription of antibacterials for under 5-year outpatient children presenting with acute diarrhoea at public health facilities in Lango sub-region (Sub-study I)
•To determine microbiologically, the burden and drivers of inappropriate prescription of antibacterials for under 5-year outpatient children presenting with UTRIs at public health facilities in Lango sub-region (Sub-study II)
•To determine the proportion of bacterial species and their resistance among under 5 year inpatient children with systemic infections at Lira Regional Referral Hospital (Sub-study III)
•To determine the prescribers’ knowledge, attitudes and practices regarding antibacterial prescription with respect to the available guidelines for under 5-year outpatient children with acute diarrhoea and URTIs at public health facilities in Lango sub-region (Sub-study IV)
 Uganda 2019-11-19 2022-11-19 Medical and Health Sciences Degree Award
Gerald Mboowa
ID:
UNDERSTANDING TRANSMISSION DYNAMICS AND ACQUISITION OF ANTIMICROBIAL RESISTANCE AT REFERRAL HOSPITALS AND COMMUNITY SETTINGS IN EAST AFRICA
REFNo: HS411ES

i. To determine the prevalence, antimicrobial resistance profiles and the common phenotypic mechanisms of resistance in bacteria isolated from study participants from the orthopaedic ward at Mulago hospital, hospital environments and corresponding community settings.
ii. To describe the emergence, transmission networks, and epidemiology of drug resistant bacteria in the orthopaedic ward at Mulago hospital, hospital environments and corresponding community settings.
iii. To investigate behaviors/practices that influence the emergence and spread of drug resistant bacteria in the orthopaedic ward at Mulago hospital, hospital environments and corresponding community settings.

 Uganda 2019-11-19 2022-11-19 Medical and Health Sciences Non-degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
 DEVELOPMENT OF A DIAGNOSTIC PREDICTION SCORE FOR TUBERCULOSIS IN HOSPITALIZED CHILDREN WITH SEVERE ACUTE MALNUTRITION
REFNo: HS445ES

Primary Objective
To develop a diagnostic prediction score for TB in hospitalized children with SAM
Secondary Objectives
1. To assess the prevalence of TB among hospitalized children with SAM.
2. To describe the symptoms and clinical characteristics of TB disease in hospitalized children with SAM.
3. To develop a first-step screening prediction score to identify children with presumptive TB among hospitalised children with SAM
4. To propose a stepwise diagnostic algorithm based on the score(s) developed
5. To assess the diagnostic performance and the added value in a diagnostic prediction score for TB in hospitalized children with SAM of the following tests:

a. Ultra performed on one NPA and one stool sample
b. Chest radiography features as assessed by the simplified TB-Speed CXR reading tool
c. Abdominal ultrasound
d. QuantiFERON®-TB Gold In-Tube (QFT) IGRA
e. Monocyte-to-lymphocyte ratio (MLR)
f. CRP
6. To assess the feasibility of collecting NPA and stool in children with SAM
7. To assess the safety and tolerability of NPA collection in children with SAM
8. To assess mortality and weight gain at 6 months in children with SAM, with or without anti-TB treatment
9. To assess the effect of bacteriological features (Xpert and/or culture-confirmed TB) and other key patient characteristics (age, HIV status, initial severity markers, percentage weight gain, and CXR features) on TB treatment outcome.

Uganda 2019-11-19 2022-11-19 Medical and Health Sciences Non-degree Award
Wilberforce Tushemereirwe
ID:
Micronutrient Biofortified Cooking Bananas for East Africa
REFNo: A53ES

The goal of the project is to contribute to the alleviation of vitamin A deficiency in Uganda through enhancing the levels of PVA in banana fruit, the major staple food of Uganda.
 Uganda 2019-11-19 2022-11-19 Agricultural Sciences Non-degree Award
Denise Ferris Nicole
ID:
Take-up and Impact of Digital Repayment in Microfinance
REFNo: SS369ES

1. To assess the effect of digital repayment on loan performance and the microfinance model.
a. Understand if access to digital repayment methods affects repayment timeliness and default rates.
b. Understand if access to digital repayment affects group cohesion
2. To assess the effects of digital repayment on microfinance clients.
a. Assess if digital repayment is beneficial for microentrepreneurial clients
b. Assess if digital repayments for microfinance loans affect other use of mobile money
3. To assess how digital repayment differentially affects those who would prefer not to take it up.
a. Assess if those forced into digital repayment change their repayment behaviour.

 Canada 2019-11-19 2022-11-19 Social Science and Humanities Non-degree Award
Tessa Laing
ID:
Community responses to processes of land acquisition and resource management for conservation in Uganda
REFNo: SS372ES

The objective of this research is to explore the dynamics that enable local land users in areas bordering protected areas across northern Uganda to collectively influence land acquisition and conservation management processes. As highlighted in a number of recent scholarly review articles, insufficient attention has been given to ‘responses from below’ to land acquisition processes (Boras & Franco, 2013; Hall et al, 2015). While scholars have focused on ‘celebrity conservation cases’ in eastern and south-western Uganda such as communities affected by Mount Elgon and Queen Elizabeth National Park, less attention has been paid to community responses to conservation development in northern Uganda and established protected areas such as Kidepo and Murchison national parks. Community – conservation dynamics amongst populations living in close proximity to smaller forest and wildlife reserves such as Otze and Matheniko have received even less scholarly attention. This research aims to contribute toward such gaps, by focusing on responses to land acquisition for conservation ‘from below’ by communities living adjacent to lesser known conservation areas in northern Uganda. Accordingly, the objectives of this research are to: a) Examine how land acquisition processes and resource management for conservation are initiated and evolve in cases in northern Uganda
b) Examine how collective responses emerge; and
c) Understand the effect collective responses have on land acquisition processes, community development, and conservation outcomes in northern Uganda.
Field research will be undertaken amongst communities living adjacent to or near protected areas, not within the protected areas themselves.
New Zealand 2019-11-19 2022-11-19 Social Science and Humanities Degree Award
Jose Saenz
ID:
Helicobacter pylori and chronic dyspepsia in eastern Uganda
REFNo: HS305ES

1) Determine the prevalence of dyspepsia and Helicobacter pylori (Hp) infection among residents in a rural community in Eastern Uganda using non-invasive diagnostic means (questionnaire, fecal Hp antigen testing). 2) Correlate dyspepsia with prevalent symptoms identified from questionnaire and results from fecal Hp antigen testing. 3) Identify additional factors associated with dyspepsia using a thorough medical and dietary history. 4) Assess efficacy of Hp eradication following standard-of-care antibiotic treatment of all participants with active Hp infection. 5) Assess efficacy of empiric omeprazole treatment in participants with chronic dyspepsia who are negative for Hp by fecal Hp antigen testing.
USA 2019-10-31 2022-10-31 Medical and Health Sciences Non-degree Award
Lotte Meinert
ID:
Imagining Gender Futures in Uganda (IMAGENU) Project
REFNo: SS301ES

The overall purpose of this project is to enhance research capacity by generating new knowledge about how changing patterns of gender partnerships relate to livelihood, education, and reproductive and mental health. This will contribute to the development of relevant social gender policies, and create debate in the wider public.

The specific objectives are to explore the following research questions, which constitute Work Packages.

1. How do men and women imagine futures of marriage and child filiation in light of current far reaching changes in patterns of partnership?
2. How are gendered livelihood possibilities affected by changes in partnership and child filiation?
3. How do patterns of gendered reproductive and mental health affect and reflect changing patterns of partnership?

4. How are changing partnership patterns related to education?
Denmark 2019-10-31 2022-10-31 Social Science and Humanities Degree Award
Prem Ramburuth
ID:
Empowerment in the Workplace: Women in Africa
REFNo: SS304ES

Objective of the study

There are several dimensions that highlight the importance of the study. The objective of this study is to facilitate deeper understanding of issues of gender bias in the workplace in a sample of countries in Africa, and in sectors where women do much of the work but receive the lowest levels of pay and the least recognition, which in turn results in financial constraints.

Specific objectives

1. To understand the place and importance of empowerment of women in the workplace.
2. To investigate the range of factors that could act as barriers to women’s inclusion and gender equity.
3. Identify areas for change and inform policy on women’s empowerment in both formal and informal economies.

 Australia 2019-10-31 2022-10-31 Social Science and Humanities Non-degree Award
Dorsa Amir
ID:
Decision-making across cultures
REFNo: SS308ES

The aim of this study is to understand how children learn to make virtuous decisions – that making the right decision-- about resources and how children learn to invest cost and effort in resources that benefit the public community. We plan to determine how these behaviors develop and change with age and how they influence cooperation in children all over the world.
 USA 2019-10-31 2022-10-31 Social Science and Humanities Non-degree Award
Grace  Turyasingura
ID:
RNAseq, secretome and HIV infection analyses of foreskin epithelial cells upon exposure to cervicovaginal fluid from healthy vs. women with bacterial vaginosis.
REFNo: HS426ES

Primary Objective (Aim 1): Compare the gene expression and secretome profile of primary foreskin epithelial cells following exposure to CVF from normal vs. BV women.
Hypothesis: BV CVF will induce an elevated pro-inflammatory and pro-chemotactic response in foreskin epithelia compared to normal CVF.
 Endpoints: Global gene expression by RNAseq
Secretome profiling by Luminex

Secondary Objective (Aim 2): Assess whether HIV-1 can directly infect primary foreskin epithelial cells following exposure to CVF from women with or without BV.
Hypothesis: HIV will infect foreskin epithelial cells in the presence of HIV- enhancing seminal amyloids, in a manner enhanced by BV CVF.
Endpoints: Assess CCR5/CD4 expression in foreskin epithelial cells, and their susceptibility to productive infection by HIV-1, following exposure to BV-CVF vs. normal CVF.

 Uganda 2019-10-31 2022-10-31 Medical and Health Sciences Non-degree Award
FLORENCE ANOBE KOMAKECH ANOBE
ID:
Sustainable WASH systems Concept One Uganda.
REFNo: SS341ES

1.To investigate factors leading to success or failure of PAYF tariff collection to incentivize preventive maintenance arrangements for sustaining hand pumps.
2.To assess the possible mechanisms of exclusion from water services that exist in communities where PAYF is implemented, and how PAYF either causes or addresses these exclusion mechanisms.

Uganda 2019-10-31 2022-10-31 Social Science and Humanities Non-degree Award
Emmanuel Mande
ID: UNCST-2023-R007045
 TESTING MEDICINAL PLANTS IN UGANDA FOR LATENCY REVERSING ACTIVITY
REFNo: HS436ES

Primary objective: To prepare soluble extracts in water and hexane from 100 different recognized medicinal plant species growing in Mabira Forest of Central Uganda.
Secondary objectives: To test these extracts for HIV latency reversing activity

 Uganda 2019-10-31 2022-10-31 Medical and Health Sciences Non-degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
 Diagnosis and treatment of non-communicable diseases and geriatric syndromes in the HIV aging population in sub-Saharan Africa.
REFNo: HS454ES

General objective.
The overall goal of the proposal is to improve capacity for detection and management of non-communicable diseases and geriatric syndromes in the aging HIV population in SSA.
Specific primary objectives
Specific Aim 1. To capture NCD endpoints and their risk factors: hypertension, cardio vascular disease (annual ECG screening), respiratory disease (peak flow meter screening and spirometry), renal disease (proteinuria and creatinine clearance), cancers (complete skin evaluation, pap smear, faecal occult blood, breast exam).
Specific Aim 2. To measure physical function using the Short Performance Physical Battery, muscle strength, (Gait speed and assessment of grip strength with handheld dynamometry), frailty phenotype, and history of falls.

Secondary objectives:
o To assess quality of life at baseline and year 1 and 2. To asses Quality of life we will use the WHOQOL-OLD (https://www.who.int/mental_health/publications/whoqol/en/). This module was developed after identifying gaps in the coverage of the standard WHOQOL-100 on aspects of QoL in older patients (29).
o To monitor medication regimens in all older patients, particularly medications that can contribute to inactivity, (e.g. sedatives), medications that cause electrolyte imbalances, and medications that slow reaction time or can interfere with balance and coordination. Polypharmacy will be defined as 5 or more drugs, beyond antiretroviral drugs, used in the same individuals for more than 4 weeks.
o To measure other geriatric syndromes (nutritional status, https://www.mna-elderly.com/; falls history https://www.sralab.org/rehabilitation-measures/history-falls-questionnaire?ID=1131) and urinary incontinence https://sagelink.ca/iciq-ui_short_form_giic) using standardized questionnaires
o To screen for depression using the People Health Questionnaires, PHQ-2 and PHQ-9, (which have been validated in our settings in HIV positive patients (30)), and treated accordingly.
o To assess disability using an HIV specific Instrumental Activities of Daily Living (IADL) tool which will be adapted from the one developed from the University of Toronto.
o To screen for dementia using the Montreal Cognitive Assessment (MoCA) https://www.mocatest.org/wp-content/uploads/2017/05/MoCA-8.3-English-Test-2018-04.pdf. As suggested by a validation study conducted in South Africa, mild cognitive impairment cut off will be lowered from 26 to 24 to take in account cultural differences [36]

 Uganda 2019-10-31 2022-10-31 Medical and Health Sciences Non-degree Award
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