Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Vianney Tushabe John
ID: UNCST-2024-R015708
Development of Multiplex Molecular Test for S. mansoni and P. falciparum Duplex using LAMP assay and Pit Latrine metagenomic sampling for community assessment
REFNo: SIR445ES

- Development of the Multiplex Malaria – Schistosomiasis assay
- Latrine Metagenomics for community diagnostics assessment 
- Validation of Molecular duplex assay technology 
Uganda 2024-12-10 14:04:09 2027-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Manon Delvaux Alizee
ID: UNCST-2024-R002311
Cultivating Cooperation: The Impact of Formalizing Land Rental Contracts on Refugee-Host Interactions and Agricultural Production in Rural Uganda
REFNo: SS3408ES

In northern Uganda, food insecurity is high for many refugees, who cultivate land for their subsistence in the vicinity of the settlements. A large majority of these refugees do not have a formal written land rental contract with their landlords. While informal institutions and agreements can have enforcement power in socially and culturally homogeneous groups, their efficiency tends to decrease with social and cultural distance. In this setting of cohabitation between Ugandans and refugees, the absence of clearly defined terms of trade often limits successful farming outcomes, as refugees’ rights to what they earn, produce, and consume are more vulnerable to changes. Suggestive evidence indicates that formal land contracts grant greater security, which can lead to increased farm profitability, investment and credit opportunities, and greater economic diversification and growth.

We will conduct a randomized pilot evaluation to measure the impact of formalized land rental contracts between refugee tenants and host community landlords. In the treatment groups, the landlords and tenants will receive support to formalize their land rental agreement. In the control group, landlords and tenants will remain with verbal and informal land rental agreements. We will evaluate indicators such as trust, social cohesion, agricultural practices, and food security. The study will also investigate why formalized land rental contracts are not more widespread in rural Uganda. The sample will include tenants from the Bidibidi, Imvepi and Rhino refugee settlements and landlords from the host communities.
France 2024-12-10 14:03:00 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
SAM ALI
ID: UNCST-2020-R014824
A Noncontact Bed-Based Platform for Passive Longitudinal Monitoring of Maternal and Fetal Cardiovascular Physiology in Uganda
REFNo: HS5320ES

Main objective
• To monitor maternal and fetal heart rate, respiratory rate, fetal movement, and sleep patterns among selected pregnant women enrolled in the iTECH study using noncontact bed sensors with the goal of better understanding both maternal and fetal physiology.

Specific objectives
1. To describe the maternal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
2. To describe the fetal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
3. To demonstrate the feasibility of measuring and extracting fetal movement signals among selected pregnant women enrolled into the iTECH study.
Uganda 2024-12-09 13:22:54 2027-12-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
Disentangling the population structure of MRSA in an urban low-income settings
REFNo: HS4699ES

1. To define the population structure of MRSA in hospital and community settings in Kampala, and identify risk factors for MRSA carriage among inpatients and individuals in the community.

2. To Investigate the probable coexistence between HA-MRSA and CA-MRSA in hospital and community in Kampala.
Uganda 2024-12-02 17:33:35 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brian Turigye
ID: UNCST-2021-R012569
QUALITY OF MATERNAL AND NEWBORN CARE; A CASE STUDY OF KASESE AND BUNDIBUGYO DISTRICTS, MIDWESTERN UGANDA
REFNo: HS5213ES

1. To describe existing evidence on the quality of Provision of Obstetric and newborn care in Uganda
2. To establish the quality of provision of Obstetric and newborn care in Midwestern Uganda
3. To explore the determinants and drivers of the quality of provision of Obstetric and newborn care in Midwestern Uganda
4. To analyze critically the existing strategies on improving the provision of Obstetric and newborn care in Midwestern Uganda and develop relevant alternatives

Uganda 2024-12-02 17:32:38 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Lively Minds Together Range and Listenership Estimation
REFNo: SS3435ES

To gather data on the signal strength of radio programs of interest,To provide evidence-based recommendations on geographic locations and radio programming for the future rollout and evaluation of the Lively Minds Together project.,To understand preferences, popularity, and other media sources related to radio programming.,To collect general information on radio listenership habits.,To gather data on the number of listeners for the radio programs of interest.,
Uganda 2024-12-02 17:31:19 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Idris Sanusi
ID: UNCST-2024-R003856
EVALUATION OF THE CONCENTRATIONS OF PHARMACEUTICALS AND HEALTH RISK ASSESSMENT IN GROUND AND SURFACE WATERS IN KAMPALA AND MBARARA REGIONS OF UGANDA
REFNo: HS5235ES

I. To assess the physicochemical parameters (pH, water temperature, electrical conductivity, total dissolved solids, total suspended solids, total solids, chlorides, nitrate, phosphate and sulphate) in the collected water samples from the selected areas as pollution indices. II. To determine the concentrations of iron, copper, mercury, cadmium, manganese and lead in surface water and groundwater of the study regions. III. To determine the concentrations of the pharmaceuticals (sulfamethoxazole, ciprofloxacin, ibuprofen, amoxicillin, cotrimoxazole, metronidazole, artemether/lumefantrine, acetaminophen, caffeine, and carbamazepine) in surface water and groundwater of the study regions. IV. To assess the spatio-temporal variation of heavy metals and pharmaceuticals in the water samples collected from the regions. V. To assess the health risks associated with the exposure to pharmaceuticals and heavy metals in the water samples collected.
Nigeria 2024-12-02 17:29:38 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Ibrahim Kasujja
ID: UNCST-2021-R013169
Food Insecurity and Mental Health among Children and Adolescents: Mixed Methods Study in Uganda
REFNo: HS4997ES

Objectives:

(1) to conduct a formative qualitative study to explore the children’s and teachers’ perceptions of food insecurity experiences and child and adolescent mental health
(CAMH) to ultimately build a framework which links food insecurity and CAMH in schools in Uganda,

(2) to conduct a reliability and validation study to assess the psychometric properties of the day scholars food insecurity experience scale (DSFIES) by examining test-retest reliability and criterion validity in
schools in Uganda, and

(3) to conduct a prospective cohort study to unpack the causal mechanisms linking food insecurity and CAMH by examining bidirectional temporal associations among seven to 13 years old children in Uganda.
Uganda 2024-12-02 17:28:44 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Timothy Opobo
ID: UNCST-2023-R006042
The Prevalence of Violence against Children in School and the Effectiveness of Reporting, Tracking, Referral and Response Mechanisms in Schools in Karamoja Sub-Region
REFNo: SS3414ES

1. Establish the prevalence and nature of VAC/VACiS among children, including their age, sex, grade, and vulnerability/disability status.
2. Identify, describe and quantify structures that children report cases of violence to when they occur
3. Identify existing mechanisms for referral, response and tracking cases of violence against children in schools?

Uganda 2024-12-02 17:24:47 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
IMPACT OF THE UNLOCK LITERACY PROJECT MODEL ON THE READING RESULTS FOR GIRLS AND BOYS IN EARLY GRADES IN UGANDA
REFNo: SS3379ES

7. To find out the challenges to implementing the Unlock literacy model in primary schools,6. To determine the cost of the UL model in the Ugandan setting,5. To identify the key lessons so far learned during implementation of the UL model.,4. To establish whether the Unlock literacy model contributes to increased support by education authorities for children\'s reading,3. To assess the extent to which the Unlock literacy model interventions are influencing support by parents or guardians and communities for children\'s reading.,2. To establish whether the Unlock literacy model contributes to strengthened teaching instruction in Primary 1–3.,1. To determine the extent to which the Unlock literacy model contributes to increased reading results of children.,The main purpose of this study is to examine the impact of the UL Project Model on the reading results for girls and boys in early grades in selected World Vision implementing districts in Uganda.,
Uganda 2024-12-02 17:21:46 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Salvatore Ssemmanda
ID: UNCST-2024-R004583
KNOWLEDGE OF ALARM SIGNS OF STROKE AMONG CARETAKERS OF STROKE PATIENTS AND FIRST CONTACT HEALTH CARE PROVIDERS AT TWO TERTIARY REFERRAL HOSPITALS IN UGANDA
REFNo: HS5181ES

General objective.

To describe how well the alarm stroke signs summarized in the BE-FAST mnemonic are known by acute stroke patients’ caretakers and first contact stroke health care providers and how this knowledge by the acute stroke patients’ caretakers affects time of arrival of stroke patients to stroke services in the two major stroke referral hospitals in the country.

Specific objectives:

> To describe the knowledge of the BE-FAST acute stroke symptoms and signs by the first contact stroke health care providers in the two major stroke referral hospitals in Kampala, Uganda

> To describe the knowledge of the BE-FAST acute stroke symptoms and signs by the acute stroke patients’ bedside caretakers in the two major stroke referral hospitals in Kampala, Uganda.

> To demonstrate the relationship between knowledge of BE-FAST acute stroke alarm signs by stroke patient caretakers and time of arrival of their stroke patients to hospital stroke services in in
the two major stroke referral hospitals in Kampala, Uganda.
Uganda 2024-12-02 17:19:44 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Obinna Barah Onyebuchi
ID: UNCST-2024-R002664
Investigation of Tribomechanical Properties of Aluminium (AA6061) Reinforced with Hybridized Agro-Marine Waste for Automotive Applications
REFNo: SIR428ES

Main Objective
This research aims to investigate the tribomechanical properties of Aluminum (AA6061) reinforced with hybridized agro-marine waste particle composites (AMWPCs) for enhanced automotive applications.
Specific Objectives
1. To assess tensile, compressive strength, and hardness characteristics of AMWPCs for ascertaining the material\'s strength under various loading conditions, and resistance to indentation or scratching respectively.
2. To investigate flexural strength, impact, and fatigue resistance of AMWPCs under dynamic loading conditions.
3. To evaluate the tribological effects and wear resistance of AMWPCs in enduring wear and friction.
4. To examine the material\'s microstructure and elemental composition using FTIR, SEM/EDS.
5. To Analyze AMWPCs phase transitions and thermal stability using DTA, and TGA.
Nigeria 2024-12-02 17:18:19 2027-12-02 Engineering and Technology Non-Clinical Trial Degree Award
Hannington Ngabirano
ID: UNCST-2024-R003312
Improving Pesticide Use in Food Crop Growing in Kigezi Sub-Region in South-western, Uganda. RefNo: KABREC-2024-238
REFNo: NS873ES

2. Training farmers and dealers in agro-inputs on pesticide use in food crops in Kabale, Rukiga, Rubanda, Kisoro, Kanungu and Rukungiri Districts.,1. Investigate pesticide use in food crops in south-western Uganda,
Uganda 2024-12-02 17:16:00 2027-12-02 Natural Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
NEOSEPSIS Project: Reducing neonatal and maternal mortality by rapid detection of sepsis in resource-limited environments
REFNo: HS5058ES

1) Explore and evaluate potential distribution channels and market entry strategies for the NeoSep SAA test. 2) Identify and analyze the barriers that may impede the widespread adoption of the NeoSep SAA test. 3) Determine the cost-effectiveness of implementing the NeoSep SAA test in clinical settings in healthcare resource limited settings and systems. 4) Assess the NeoSep SAA test’s performance as compared to CRP test. 5) Evaluate the applicability of the NeoSep SAA test for the detection of maternal sepsis occurring after the first five days of birth. 6) Assess the NeoSep SAA test’s utility in monitoring response to antibiotic therapy in neonates who have undergone treatment for sepsis.7) Evaluate the diagnostic performance of the optimized NeoSep SAA test for neonatal sepsis by evaluating its sensitivity, specificity, PPV, and NPV.
Uganda 2024-12-02 17:12:10 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Katende
ID: UNCST-2023-R006954
ASSESSMENT OF THE CURRENT STATE OF CHILD TRAFFICKING INTO WORST FORMS OF CHILD LABOUR IN NAPAK AND KAMPALA DISTRICT, UGANDA
REFNo: SS2547ES

i. To assess the current nature and dynamics of child trafficking in Napak and Kampala districts.

ii. To indentify the current key factors contributing to child trafficking in Napak district.

iii.To evaluate the community awareness and acceptance levels regarding child trafficking in Napak district.

Uganda 2024-12-02 17:10:31 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
PROJECT MID TERM EVALUATION OF WATER SANITATION AND HYGIENE FOR SEXUAL REPRODUCTIVE HEALTH AND RIGHTS IN AMURU DSITRICT, NORTHERN UGANDA (PIWA Maleng II Project).
REFNo: SS3385ES

1.2 Purpose of the research study/study protocol
To highlight the evaluation process that will be followed during the mid-term evaluation that aims at determining the access and utilization of SRHR services among youths, establishing the barriers and enablers to SRHR services and establish the effect of integration of SRHR and WASH on Menstrual hygiene management among adolescents and youths in communities and schools in Lamogi and Pabbo sub counties in Amuru district.

1.3 Specific objectives of the mid-term evaluation
This mid-term evaluation will aim to achieve the following broad objectives;
i. Determine the level of access and utilization of SRHR services among adolescents and youths in target communities of Pabbo and Lamogi sub counties.
ii. Establish the barriers and enablers of SRHR services uptake among adolescents, youths and women at target communities in Lamogi and Pabbo sub counties.
iii. Establish the effect of integration of SRHR and WASH on Menstrual Hygiene Management among adolescents and youths in target communities and schools of Lamogi and Pabbo sub counties.

Uganda 2024-12-02 17:09:15 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ivan Sserwadda
ID: UNCST-2022-R009568
Respiratory Microbiome: insights into the diagnosis and pathogenesis of Tuberculosis
REFNo: HS4329ES

To understand the role of bacterial, viral and fungal colonization or infection (other than Mycobacterium tuberculosis) in pulmonary TB and in the clinical performance of potential TB triage tests.,To employ the Sanity Respiratory Pathogen Panel (RPP36) for culture and sensitivity testing to identify clinically relevant respiratory pathogens in presumptive tuberculosis patients,To determine the association of the respiratory microbiota and socio-demographic characteristics among presumptive and confirmed tuberculosis patients,To determine the correlation between the clinically significant microbiota and clinical presentation among presumptive and confirmed tuberculosis patients,To determine the clinically significant pathogens co-infecting the presumptive tuberculosis patients ,A systematic review of the respiratory microbiome changes in relation to Tuberculosis,
Uganda 2024-12-02 17:07:10 2027-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Betty Akurut Enyipu
ID: UNCST-2021-R013556
Prevalence of Anxiety and Depression Among Students of Uganda Christian University
REFNo: SS3474ES

Development of Innovative Psychotherapy Models: The project will result in the development of group-based psychotherapy models specifically designed to address depression and anxiety among university students. These models will draw upon evidence-based practices while also incorporating culturally relevant elements to ensure effectiveness within the Ugandan context.,
Uganda 2024-12-02 17:06:13 2027-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
ASSESSING THE KNOWLEDGE AND ATTITUDES OF CAREGIVERS TOWARDS PAEDIATRIC ORTHOPAEDIC SURGERY AT CORSU HOSPITAL
REFNo: HS5217ES

primary objectives;
-To assess the knowledge and attitude of caregivers towards paediatric orthopaedic surgery at CoRSU Hospital

Secondary Objectives
1. To determine the caregivers’ knowledge towards paediatric orthopaedic surgery at CoRSU hospital.
2. To determine the caregivers’ attitude towards pediatric orthopedic surgery at CoRSU hospital 3. To identify factors influencing caregiver decision-making in pediatric orthopaedic surgery
Uganda 2024-12-02 17:05:18 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
Affordances of makerspaces influencing biomedical undergraduate engineering students' design learning and curriculum localization in Uganda and the USA
REFNo: SIR448ES

Main Objective
To explore and compare how the affordances of the DesignCube makerspaces at Makerere University and Duke University influence biomedical engineering students' design learning and the localization of curriculum by the end of the study period.

Specific Objectives
1.To determine the perceived affordances of the DesignCube makerspaces among undergraduate biomedical engineering students at Makerere University and Duke University within the first four weeks of their engagement in the design coursework.

2.To assess the actual affordances of the DesignCube maker spaces after students’ full engagement with the prototyping and design coursework by the end of the academic term.

3.To identify the factors that foster or limit student engagement with the DesignCube makerspaces at Makerere University and Duke University by the completion of the study.

4.To evaluate how the affordances identified in each context (Makerere and Duke) inform the localization and adaptation of curriculum and pedagogy for design learning in biomedical engineering by the final stage of the study.
Uganda 2024-12-02 17:04:31 2027-12-02 Engineering and Technology Non-Clinical Trial Non-degree Award
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