Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Rogers Kajabwangu
ID: UNCST-2022-R010077
Cervical cancer and metabolic syndrome among women utilizing cervical cancer prevention and treatment services at Mbarara regional referral hospitals
REFNo: HS3053ES

To describe the disease burden and trends of cervical cancer, and its relationship with Metabolic syndrome among women at Mbarara regional referral hospital.
Uganda 2023-09-26 9:29:37 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ULTRA Covi-Catch Ag. Laymen Study including Usability. "Clinical Performance Study Plan - CPSP nr. BSS-CPH 22-054"
REFNo: HS2933ES

Part 3: Observed untrained user study o Evaluation of test results and interpretations when performed by laymen in a self-testing environment while being observed by healthcare providers. These observations will be captured using a questionnaire-based survey.,art 2: Results interpretation study o Reading and interpretation of 6 contrived devices by a minimum of 100 laypersons while being supervised by a neutral healthcare provider. The contrived devices should reflect the different ranges of reactivity: ? non-reactive (x 1) ? reactive (x 1) ? weak reactive (x 2) ? invalid (x 2).,Part 1: Labelling comprehension study o Questionnaire-based-survey to assess whether the key messages and instructions from packaging and labelling are understandable and easy to follow.,The objective of this laymen study is to establish the usability of the ULTRA Covi-Catch Ag in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2023-09-26 12:24:11 2026-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phillip Ssekamatte
ID:
IMMUNOLOGICAL, METABOLIC AND GENE TRANSCRIPTIONAL CHANGES AMONG PATIENTS WITH TUBERCULOSIS AND TYPE 2 DIABETES MELLITUS IN UGANDA (IMG STUDY)
REFNo: HS2990ES

Sub-study 1: To evaluate the immunologic, metabolic, and genetic mechanisms of TB susceptibility in DM. Sub-study 2: To assess baseline differences in Mtb-specific CD4+ and CD8+ T cell functional phenotypes and memory frequencies among LTBI and ATB patients with and without T2DM. Sub-study 3: To determine the effect of TB preventive therapy using isoniazid therapy on the function and memory frequency of Mtb-specific CD4+ and CD8+ T cells among LTBI and ATB patients with and without T2DM. Sub-study 4: To profile baseline immune-metabolic changes among LTBI and ATB patients with and without T2DM. Sub-study 5: To investigate gene expression differences in the 6-gene transcriptome signature (TB RISK6; GBP2, SERPING1, FCGR1B, TRMT2A, SDR39U1, TUBGCP6) among LTBI and ATB patients with and without T2DM at baseline and 6 months of TB preventive therapy.
Uganda 2023-09-26 12:13:20 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Ambaru  Ojia Jacinta
ID:
PREVALENCE OF SEPSIS, 30 DAY CASE FATALITY RATIO, AND OPTIMAL MORTALITY RISK SCORES AMONG POST-CHEMOTHERAPY CANCER PATIENTS WITH INFECTION AT ONCOLOGY CLINIC MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS3111ES

Aim 3. To determine the optimal mortality risk score to predict 30-day mortality for post cancer-chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital,Aim 2. To determine the 30-day case fatality ratio for post-cancer chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital ,Aim 1: To determine the point prevalence of sepsis in post-cancer chemotherapy patients with infection, according to mortality risk scores (qSOFA, UVA, SIRS), at Mbarara regional referral hospital ,To determine the prevalence of sepsis, 30-day case fatality ratio and optimal mortality risk score, among patients with post-cancer chemotherapy infection at oncology clinic MRRH,
Uganda 2023-09-26 12:11:47 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
MARTIN CHEBET
ID: UNCST-2021-R013905
THE INCIDENCE AND AETIOLOGY OF STILLBIRTHS IN EASTERN UGANDA
REFNo: HS3112ES

3. To assess the acceptability of minimal invasive autopsy in Eastern Uganda,2. To determine the infections associated with stillbirths in a regional referral hospital in eastern Uganda,1. To determine the incidence of and risk factors for stillbirths in a cluster-randomised trial cohort of pregnant women (the BabyGel trial) ,
Uganda 2023-09-26 12:04:01 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
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