Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Adoke Yeka
ID: UNCST-2021-R004300
Phase IIa Proof of Concept, Multicenter, Randomized, Open-label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of the Combination M5717 plus Pyronaridine Administered once Daily for 1 or 2 Days to Adults and Adolescents with Acute Uncomplicated Plasmodium falciparum Malaria
REFNo: HS2736ES

To evaluate the safety and
tolerability of the M5717-
pyronaridine combination in
adult participants with acute
uncomplicated malaria due to
P. falciparum.
Secondary.
o describe the clinical efficacy
of the M5717-pyronaridine
combination in adult participants
with acute uncomplicated
malaria due to P. falciparum
Uganda 2023-03-16 12:35:56 2026-03-16 Medical and Health Sciences Clinical Trial Non-degree Award
Charles Masembe Kikubo
ID: UNCST-2019-R001092
The Dispersal of Antibiotic Resistance and Antibiotics in Water Ecosystems and Influence on livestock and Aquatic wildlife (PAIRWISE)
REFNo: A240ES

i) To investigate the dispersal of Antibiotic Resistant Bacteria (ARB), Antibiotic Resistant Genes (ARG) and Antibiotics (ATB) in surface waters downstream of WWTPs ii) To investigate the carriage of ARB and ARG in livestock linked to surface waters influenced by WWTPs iii) To ascertain the role of aquatic birds in dispersal of ARB and ARG
Uganda 2023-03-09 23:54:51 2026-03-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Francis Garuzooka John
ID:
Investment practices of persons with a disability in informal microfinance groups in Uganda
REFNo: SS1617ES

1. Examine the attitudes of persons with a disability regarding investment, saving and borrowing from VSLAs and ROSCAs in selected districts in Uganda. 2. Analyse what influences the persons with a disability’ investment choices as individuals and members of groups (Revised as: Analyse what influences persons with disabilities’ investment choices as individuals and as members of groups.) 3. Explain how persons with a disability acquire the knowledge and skills they use while investing resources obtained from VSLAs and ROSCAs. 4. Describe the experiences that persons with a disability have regarding investment of loans obtained from VSLAs and ROSCAs in selected districts in Uganda.
Uganda 2023-03-09 23:52:14 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bonniface Oryokot
ID:
Adaptation and Evaluation of the Operation Triple Zero (OTZ) model to improve Retention and HIV viral suppression among the Adolescents Living with HIV in TASO Uganda using the RE-AIM framework.
REFNo: SS1610ES

• To implement and test the adapted OTZ intervention from January 2023 to end of August 2023.,• To adapt and design the OTZ model to the TASO Uganda context,• To determine the barriers and facilitators to Retention and VLS,• To improve health outcomes among CALHIV in selected TASO Uganda COEs.,
Uganda 2023-03-09 23:48:16 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
Observational study on management of post-partum haemorrhage at Kawempe National Referral Hospital (REBOA-PPH baseline study)
REFNo: HS2730ES

To suggest a customized training to improve PPH management in a large referral hospital in Uganda,To identify specific areas of potential improvements in PPH management,To describe the actions taken in the process of managing PPH among mothers admitted to KNRH,To describe the current management of severe PPH with timelines from identification until bleeding is controlled,To map the occurrence of severe PPH among birthing mothers admitted at Kawempe National Referral Hospital (KNRH),The aim of this study is to map the occurrence of severe post-partum haemorrhage (PPH) and its current management and to identify potential improvements in the management of severe PPH in a large referral hospital in Uganda. ,
Uganda 2023-03-09 23:43:20 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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