Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Abel  Kakuru
ID: UNCST-2022-R009193
Perennial Malaria Chemoprevention With Dihydroartemisinin-Piperaquine Versus Sulfadoxine-Pyrimethamine Plus Amodiaquine Versus No Chemoprevention: A Double Blind Randomised Controlled Trial
REFNo: HS7437ES

1. To compare the protective efficacy of combining R21 vaccination with PMC-DP or PMC-SPAQ vs R21 alone up to 5 years of age.
2. To compare the safety and tolerability of combining R21 vaccination with PMC-DP vs. PMC-SPAQ.
3. To determine the impact of PMC on the drug resistance landscape and R21-specific immunogenicity and durability.

Uganda 2026-07-16 20:29:47 2029-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Andrew Muhumuza
ID: UNCST-2022-R009010
CAN TOUCH HELP IDENTIFY PATIENTS WHO NEED AN IMMEDIATE FULL CLINICAL ASSESSMENT BY A PHYSICIAN?
REFNo: HS7768ES

To find out if touch can help identify patients who need an immediate full clinical assessment by a physician.,To compare the ability to predict 24-hour mortality by temperature and moisture subjectively assessed by touch in different parts of the body ,To compare the ability of temperature and moisture subjectively assessed by touch to predict 24-hour mortality with standard thermometry and the National Early Warning Score,
Uganda 2026-07-16 20:26:26 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MOREEN ASASIRA
ID: UNCST-2026-R023307
Climate Resilient Tea Innovations In Uganda: A Case of Nature-Based Strategies in The Tea Value Chain
REFNo: A775ES

1.To evaluate farmer awareness, perceptions, and attitudes about the use of nature-based innovations in tea production 2.Establish the probability of use of nature-based innovations in tea production 3.To map the Uganda tea value chain 4.Establish perceived actor preference of the resilient tea varieties among tea chain actors
Ugandan 2026-07-16 20:13:13 2029-07-16 Agricultural Sciences Non-Clinical Trial Degree Award
Faizo Mugerwa
ID: UNCST-2025-R021837
EVALUATION OF THE FEASIBILITY AND ACCEPTABILITY OF AN EXHALED BREATH CONDENSATE SAMPLING DEVICE TO COLLECT A RESPIRATORY SAMPLE FOR LIPOARABINOMANNAN TESTING AMONG SUSPECTED TUBERCULOSIS PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL (EXHALE STUDY)
REFNo: HS7963ES

To determine the sensitivity, specificity, of the Alere LAM test if used to test the sample collected by the EBC device among suspected tuberculosis patients. To assess the feasibility and acceptability of the EBC sampling device by patients, and healthcare workers. To determine the positive and negative predictive values of the Alere LAM test if used to test the sample collected by the EBC device among suspected tuberculosis patients.
Uganda 2026-07-16 20:11:09 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
PHASE IV HUMAN LACTATION STUDY TO DESCRIBE THE PHARMACOKINETICS OF SEMAGLUTIDE IN LACTATING MOTHER-INFANT PAIRS IN UGANDA
REFNo: HS7927ES

Primary Objective
To define the transfer of semaglutide from mother to
breastfed infant during the postpartum period.

Secondary Objectives
? To determine the effect of maternal semaglutide on
breastmilk composition
? To determine the effect of maternal semaglutide on
breastmilk volume and breastfeeding practice
(frequency, duration)
? To determine the effect of maternal semaglutide on
infant growth
? To determine the effect of maternal semaglutide on
maternal HbA1c
? To measure the effect of maternal semaglutide on
body composition (BMI, lipid profile, hip/waist
circ)
? To evaluate participant perceptions of semaglutide
use and the paradigm of postpartum initiation of
medication
? To calibrate semaglutide PBPK model to predict
untested clinical scenarios (infant oral bioavailability,
maternal dose, dose ranges, milk
characteristics/composition)
UK 2026-07-16 20:06:07 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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