alfred bulamu
ID: UNCST-2023-R008638
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Uganda Translational Breast Cancer Screening Research Center with Innovations in MRI and Genetic Testing.
REFNo: HS4689ES
Implementation of breast MRI with genetic testing as BC screening method for women at high risk of BC by July 2029 (Phase 6) , Continuous Trainings for radiologists, radiographers and laboratory staffs on the modern technologies of MRI and Genetic testing (phase 3 to phase 6) ,Evaluating the feasibility of screening BC using MRI and genetic testing for high risk women by December 2028 (phase 5),Large scale education of the community about BC by July 2028 (phase 3 and phase 4).,Large scale determination of the utility of genetic testing as a screening modality for BC in Uganda by perform mutational genetic analysis for women at high-risk aged19 years to 80 years by July 2028 (phase 3 and phase 4) , Large scale determination of the utility of quantitative breast MRI for screening women at high risk BC aged 19 years to 80 years by July 2028 (phase 3 and phase 4) ,Training of the users on equipment i.e. Radiologists, Radiographers and laboratory staffs by 2025 (phase 2) ,Securing and installation of lab equipment for genetic testing by 2025 (Phase 2,Securing and installation of MRI with Breast coils by July 2025 (Phase 2),To build capacity for 20 laboratory health care workers in genetic testing technologies by December 2023 (phase 1).,To build capacity for 30 radiology health professionals in modern breast Imaging with MRI by December 2023 (Phase 1),To determine the utility of quantitative breast MRI for screening women at high risk breast cancer aged 19 years to 80 years by July 2024 (phase 1),To determine the utility of genetic testing as a screening modality for BC in Uganda by perform mutational genetic analysis for women at high-risk of BC aged 19 years to 80 years, by July 2024 (phase1),To build a long-lasting infrastructure for research, clinical screening in Uganda and training using modern technologies. ,To offer improved access to Breast Cancer screening in Uganda through quantitative MRI and genetic testing research center,
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Uganda |
2024-08-06 17:27:31 |
2027-08-06 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Edward Nahurira
ID: UNCST-2022-R009739
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Comparative Phytochemical Studies of Callus Regenerated from Leaf Explant of Prunus Africana (Hook F. Kalkman) and Stem Bark of the Same Mother Plant
REFNo: HS2434ES
1. To develop callus culture from the explant of P. africana leaf and stem bark.
2. To evaluate the phytochemical constituents of the callus extracts of P. africana leaf and stem bark explant.
3. To develop and compare the TLC and HPLC fingerprints of each extract for their identification.
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Uganda |
2024-08-06 17:22:37 |
2027-08-06 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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ANITA ARINDA
ID: UNCST-2020-R014158
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Intellectual Disability in Children and Adolescents with Epilepsy in Mulago and Butabika National Referral Hospitals: Prevalence and Associated Factors
REFNo: HS4589ES
2. To determine the factors associated with ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,1. To determine the prevalence of ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,To determine the prevalence of and factors associated with ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,
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Uganda |
2024-08-05 14:04:37 |
2027-08-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Moses Oketch
ID: UNCST-2024-R004313
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Long-Term Impacts of Improved Childhood Literacy
REFNo: SS2796ES
Economic situation,
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UK |
2024-08-05 14:01:33 |
2027-08-05 |
Social Science and Humanities |
Clinical Trial |
Non-degree Award |
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Jonathan Mayito
ID: UNCST-2019-R000490
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Detection of Mycobacterium tuberculosis in blood of tuberculosis patients and their contacts in Uganda
REFNo: HS4553ES
To determine whether Mtb strains isolated from the sputum/blood of index cases with pulmonary TB are genetically identical to those detected in the blood of their contacts,To establish whether detection of Mtb in blood using the methods above associates with either of the following biomarkers of host immune response: - QFT-Plus - Blood RNA signatures for incipient tuberculosis,To determine whether Mtb can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using any of the following methods: - GeneXpert® MTB/RIF Ultra (Cepheid) - Fluorescence microscopy - Blood culture - Targeted Next-Generation Sequencing,The primary objective of this study is to determine whether Mtb DNA can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using digital PCR,
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Uganda |
2024-08-05 13:49:07 |
2027-08-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
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Construction and Validation of a Poverty Assessment Survey Tool to Inform Ambulatory Care and Surgery Cost Waiver or Subsidization in a Developing Country
REFNo: HS4463ES
To determine the weights of each attribute per item, in the constructed and validated tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To construct a validated ambulatory care and surgery-context poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To analyze the data earlier collected using the ambulatory care and surgery-context poverty assessment survey tool at KSC, for principal components,To conduct content validity and reliability testing of the ambulatory care and surgery- context poverty assessment survey tool, previously developed with adaption of some items from the simple poverty score tool for Uganda,To construct and validation of a poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,
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Uganda |
2024-08-05 13:12:56 |
2027-08-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Vesall Nourani
ID: UNCST-2022-R009221
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Impact of on-demand irrigation service : Evidence from Uganda
REFNo: SS2112ES
Do certain intermediaries (providers of agricultural inputs) facilitate efficient information aggregation and dissemination of farming knowledge between farmers?,
|
USA |
2024-08-05 13:11:25 |
2027-08-05 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Lawrence Okidi
ID:
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NUTRITIONAL QUALITY AND MICROBIAL SAFETY OF SELECTED INDIGENOUS FOODS FOR CHILDREN UNDER FIVE: A CASE STUDY OF KARAMOJA SUB-REGION OF UGANDA
REFNo: A51ES
1.3 Objectives
1.3.1 General objective
To contribute to food security by investigating the nutritive quality and safety of indigenous foods for children under five in Karamoja sub-region.
1.3.2 Specific objectives
i. To assess household handling practices of selected indigenous foods for children under five in Karamoja sub-region
ii. To determine the nutritional quality of selected indigenous foods for children under five in Karamoja sub-region
iii. To determine the microbial load and diversity of selected indigenous foods for children under five in Karamoja sub-region
iv. To determine the dietary exposure risk of children under five to pathogenic microorganisms from selected indigenous foods in Karamoja sub-region
|
Uganda |
2024-08-02 17:46:01 |
2027-08-02 |
Agricultural Sciences |
|
Degree Award |
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Charles Masembe Kikubo
ID: UNCST-2019-R001092
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Investigating the dynamics and clinical outcome of African swine fever infection at pig farms in an endemic livestock wildlife setting in Uganda
REFNo: A355ES
1) Assess the spatial distribution of pig farmers in the study areas and recruit them
2) Determine the ASF virus molecular characteristics in apparently healthy domestic pigs
3) Determine the genetic characteristics and relationships of ASFV isolated from domestic pigs
4) Determine the full genome characteristics of the unique lineages obtained from domestic pigs
5) To establish an ASF biobank of clinical materials that are curated with clinical outcomes
6) Establish Ugandan Genotype IX repository at PIADC - for genomics and vaccine research
7) Build rapid ASF whole genome sequencing capacity in endemic settings
|
Uganda |
2024-08-01 16:54:11 |
2027-08-01 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
David Kibirige
ID:
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DESIGN AND IMPLEMENTATION OF A PV SYSTEM FOR EMERGENCY SITUATION IN HEALTH FACILITIES IN RWEBISENGO UGANDA
REFNo: SIR363ES
4. To carryout hardware design and field test of the PV system,3. To design an improved inverter system for both AC single phase and three phase for PV application.,2. To model a PV power system circuit using Proteus software as well as carrying out its dynamic modeling using Simulink,1. To carry out Electrical and thermal analysis of a PV system to be used during the study,The aim of this research is to design a PV system that can be utilized during emergency situation in health facilities in Rwebisengo Uganda.,
|
Uganda |
2024-08-01 16:05:23 |
2027-08-01 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
EDWINAH ATUSINGWIZE
ID:
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Exploring Stakeholder perspectives of the social determinants of malaria in Uganda
REFNo: HS4271ES
3. To explore barriers and facilitators to addressing the social determinants of malaria.,2. To examine how the social determinants of malaria are addressed in policy making and practice. ,1. To explore stakeholder perspectives of the social determinants of malaria.,The overall aim of this study is to explore stakeholder perspectives and experiences of the social determinants of malaria in Uganda in order to inform malaria prevention policy and practice. ,
|
Uganda |
2024-07-26 16:04:20 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Alen Musisi
ID: UNCST-2022-R009338
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Knowledge, Attitude, and Practice on Radiation Protection Among Radiation Safety Officers in Uganda.
REFNo: HS4617ES
To determine the radiation protection knowledge level among RSOs
To determine the level of attitudes of RSOs towards radiation protection and safety
To determine radiation protection practices among RSOs
|
Uganda |
2024-07-26 16:03:08 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Jean Damascene Niyonsenga
ID:
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Role of PT in Ugandan Neurosurgical Transitional Care
REFNo: HS4400ES
This study aims to determine acceptability and feasibility of utilizing an interdisciplinary discharge planning protocol to improve team communication and increase patient referral to outpatient rehabilitation services in two public Ugandan hospitals.
|
Rwanda |
2024-07-26 16:01:48 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Mbisi Muhindo Enosh
ID:
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HOST COMMUNITIES’ RELATIONS AND REFUGEE ADAPTABILITY AT KYAKA II AND KYANGWALI SETTLEMENTS IN WESTERN UGANDA
REFNo: SS2953ES
To examine the role of social cohesion within host communities in facilitating refugee adaptability at Kyaka II and Kyangwali settlements,To investigate how Attitudes and Perceptions of host communities influence Refugee Adaptability at Kyaka II and Kyangwali settlements,To assess the socio-economic and political factors contributing to refugee adaptability at Kyaka II and Kyangwali settlements,To examine the impact of legal and policy framework on Refugee Adaptability within Host communities at Kyaka II and Kyangwali settlements in Uganda,To examine the dynamics and factors influencing the relationship between host communities and refugees, and to understand the impact of this relationship on the adaptability and integration of refugees at Kyaka II and Kyangwali settlements,
|
Uganda |
2024-07-26 15:59:56 |
2027-07-26 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Doris Kwesiga
ID:
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Implementer’s Voices: An input to the Lancet Commission on Evidence-based Implementation in Global Health
REFNo: HS4408ES
To examine the insights and experiences of LMIC health sector implementers on the use of evidence in their work, so as to identify barriers and enablers and design interventions to increase evidence-based implementation.,ii. What are the gaps between evidence and implementation, and how can these be closed?,i. How and why, do (or don’t) implementers use evidence? ,
|
Uganda |
2024-07-26 15:58:42 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Ismail Draguma Legason
ID: UNCST-2021-R012130
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Molecular profiling of Epstein-Barr virus genome and expression in endemic Burkitt Lymphoma (EBVL study)
REFNo: HS4198ES
1. The main goal of the study is to examine the molecular architecture of EBV, its expression pattern, and the determinants of viral pathogenesis in endemic Burkitt lymphoma. ,Perform differential gene expression and protein analysis on formalin fixed-paraffin embedded BL tissues using RT- PCR or NanoString and analyse the data for: i) differentially expressed genes and proteins ii) gene and protein expression levels iii) correlation with tumour stage and viral strains ,Perform whole genome sequencing of EBV from clinical samples (ctDNA for eBL and plasma for healthy controls) and analyse data for: i) viral strains and co-infection ii) Mutations (SNVs, Indels, and structural variants) and compare frequencies iii) mutational signatures iv) viral population structure -phylogenetics and decomposition matrices to infer evolutionary relatedness with publicly available strains. ,
|
Uganda |
2024-07-26 15:56:08 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Sarah Mayanja
ID:
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Effect of the Triple S technology on farmers' food security in northern and eastern Uganda
REFNo: A438ES
3. To compare the extent to which sweetpotato augments smallholder’s food availability amongst users and non-users of the Triple S technology ,2. To assess the values which motivate use and uptake of the Triple S technology by smallholder farmers,1. To compare the Knowledge, Attitudes and Perceptions towards the Triple S technology by users and non-users of the technology ,Overall objective: To assess the contribution of the ‘Triple S’ technology on farmers food security in the northern and eastern regions of Uganda.,
|
Uganda |
2024-07-26 15:54:12 |
2027-07-26 |
Agricultural Sciences |
Non-Clinical Trial |
Degree Award |
|
Adam Lichtenheld
ID: UNCST-2024-R004326
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Re:Build – Building Business and Social Networks to Strengthen Refugee Economic and Social Integration
REFNo: SS2803ES
The effect of the intervention on approaches of collaboration and information sharing,The effect of the intervention on psychological and social dimensions for each individual,The effect of the intervention on business outcomes (profit, savings, business growth),The effect of the intervention on network constellations in participants’ egocentric business networks,1. How can interventions support the development of business networks for refugees and nationals in urban markets of developing countries? ,
|
USA |
2024-07-26 15:50:47 |
2027-07-26 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Grace Kaweesa
ID:
|
THE EFFICACY OF BIOCHAR AND VERMICOMPOSTS INTEGRATED WITH NPK BLENDED FERTILIZER ON SOIL BIOCHEMICAL PROPERTIES, NUTRIENT USE EFFICIENCY, YIELD AND GRAIN QUALITY OF UPLAND RICE (Oryza Sativa L.) IN CENTRAL UGANDA
REFNo: A447ES
To contribute to improved food security by increasing upland rice yields through optimizing fertilizer use efficiency using biochar and vermicomposts in central Ugandai. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with VCs on growth and yield of upland riceii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on selected soil biochemical properties. iii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on nitrogen and phosphorus use efficiencies and uptakes in upland rice productioniv. To ascertain the effect of biochar and different rates of NPK blended fertilizers integrated with diverse VCs on selected nutritional qualities of upland rice grains.
|
Uganda |
2024-07-26 15:48:47 |
2027-07-26 |
Agricultural Sciences |
Non-Clinical Trial |
Degree Award |
|
Sarah Kiguli
ID: UNCST-2021-R013020
|
In-Hospital Mortality Among Sickle-Cell Disease Patients with and without SARS-CoV-2 co-Infection at Mulago National referral Hospital.
REFNo: HS4253ES
Genral OBJECTIVE
The overall objective of this study is to determine the in-hospital annual mortality rate among SCD patients over the 2010 to 2022 13 years period, and the association with SARS-CoV-2 infection-related morbidity and mortality in Uganda.
SPECIFIC OBJECTIVES
1.To determine prevalent SCD events and time-trend (annual) of in-hospital mortality rate before the COVID-19 pandemic (2010 to 20190) at Mulago National referral & Teaching Hospital
2. To assess probable-cause of death by adjudicating the diagnosis made at the time of death
3. To investigate the individual and health system factors (e.g., pediatricians with SCD expertise, pediatric ICU, oxygen supply, blood bank, and access to Hydroxyurea) associated with in-hospital mortality
4. To assess the prevalence of SARS-CoV-2 infection and any bidirectional effect between SARS-CoV-2 and SCD on mortality among those with vs. without SARS-CoV-2 or SCD admitted in hospital between 2020 and 2022.
|
Uganda |
2024-07-26 15:47:47 |
2027-07-26 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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