wasswa william
ID: UNCST-2019-R001217
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Automated Diagnosis and Classification of Cervical Cancer from Pap-Smear Images.
REFNo: HS129ES
The general objective of this research is to design and validate a robust automated tool for diagnosis and classification of cervical cancer using hybrid Segmentation and Classification techniques applied to Pap smear images. To achieve this objective and address the research problem, the following specific research objectives have been formulated.
1. To review state of art prominent recent publications focusing on the application of machine learning and medical imaging in automated detection and classification of Cervical Cancer from Pap-smear images.
2. To acquire Pap-smear images and develop a hybrid technique for automated segmentation and classification of cervical cancer.
3. To develop an interactive graphical user interface (GUI) platform to facilitate the automated diagnosis and classification of cervical cancer from Pap-smear images.
4. To test and validate the developed platform using patient results obtained from a manual screening of the Pap-smear images by a trained and experienced cytologist and also comparing the algorithms with results obtained by other researchers on the same open source datasets (Hervlet Cervical cancer dataset).
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Uganda |
2018-05-22 |
2021-05-22 |
Medical and Health Sciences |
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Degree Award |
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Aleksey Maro
ID:
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Frugivory and fermentation: a study of fruit-ethanol concentrations and olfactory plume availability for chimpanzee-consumed fruits
REFNo: NS41ES
To collect fruit ethanol data, as it relates to the diet of chimpanzees; to determine the ecological role of ethanol in nature, including relevance to human alcohol consumption.
(i) To assess the ethanol concentrations and physical properties (relative to ripeness) of fruit available to wild chimpanzees; (ii) to systematically collect, analyze, and map atmospheric ethanol vapor levels in relation to distance from ripe fruit crops of trees and shrubs.
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USA |
2018-05-22 |
2021-05-22 |
Natural Sciences |
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Degree Award |
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ERIC WOBUDEYA
ID: UNCST-2019-R001047
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Evaluation of novel diagnostics and biomarkers for childhood TB
REFNo: HS169ES
Our primary specific aim is:
1. To determine the diagnostic accuracy of a novel breath sensor for diagnosis of childhood TB.
Our secondary aims are:
1. To determine if breath volatile organic compounds (VOCS) (methyl nicotinate and methyl-p-anisate) can be used to monitor response to anti-TB treatment in children.
2. To assess the accuracy of point of care (POC) C-Reactive Protein (CRP) as a triage test among children suspected of having TB
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Uganda |
2018-05-22 |
2021-05-22 |
Medical and Health Sciences |
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Non-degree Award |
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Priya Kumar
ID:
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Technology to Enable Universal Health Coverage - Watsi Implementation Research
REFNo: HS181ES
General Objective - To determine if a technology intervention reduces the time and cost of administering community based health insurance compared to a paper based system.
The specific objectives of conducting the research include:
1. To estimate with excellent accuracy and precision the mean and median time of each of the five components of the CBHI system (member enrollment, identification, claims submission, claims approval, reporting), and of the total time for both intervention and the control cohort.
2. To estimate with excellent accuracy and precision the mean and median cost of each of the five components of the CBHI system, and of the total cost for both intervention and the control cohort.
3. To estimate with excellent accuracy and precision the difference in the mean and median time and cost between the intervention and the control cohort for each of the five components, and the total of all five components for the CBHI system.
4. To identify factors other than the technology intervention that could potentially be associated with total duration time and cost.
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USA |
2018-05-22 |
2021-05-22 |
Medical and Health Sciences |
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Non-degree Award |
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HUSSEIN ORIA
ID:
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ARV Medicines usage in farm chicken; exploring the perceptions of the community: a case for Wakiso district.
REFNo: HS188ES
Determine extent of use of ARVs in farm chicken and explore the perceptions of the community on use of ART medicines in farm chicken.
With specific objectives as;
Understand the extent of ARV usage in farm chicken.
Explore community perceptions on ARV misuse in farm chicken.
Examine the extent of ARV usage in preparation of chicken feeds.
Determine ARV content in farm chicken.
Determine the content of ARV in chicken feed
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Uganda |
2018-05-22 |
2021-05-22 |
Medical and Health Sciences |
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Non-degree Award |
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Bethany WILLIAMS LIN
ID:
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Testing the functional significance of divergent reproductive traits in an African cichlid fish (Pseudocrenilabrus multicolor victoriae)
REFNo: NS52ES
The goal of the proposed research is to better understand the influence of environmental stressors (such as turbidity, hypoxia, and increased temperature) on the divergence of reproductive traits in an African cichlid fish (Pseudocrenilabrus multicolor victoriae).
My specific objectives will be to
(a) determine the functional role of physiological and behavioral trait changes
between populations of P. multicolor, and
(b) test the adaptive significance of trait changes by assessing performance of lab-reared fish on reproductive tasks.
(c) present conservation education materials about the importance of biodiversity to water quality to local schools through The Water Project
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USA |
2018-05-22 |
2021-05-22 |
Natural Sciences |
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Degree Award |
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William NESBITT Alexander
ID:
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Causes and implications of the depletion of effective calcium concentrations in Lake Nabugabo, Uganda, East Africa
REFNo: NS53ES
To re-evaluate the work of Beadle (1981) and accurately measure the calcium and other major ion concentration of Lake Nabugabo and the surrounding wetlands.
To identify the sink of calcium in the system to see why the concentration is so low compared to other lakes in the LVB.
To explore the implications of low calcium by investigating the Ca/P ratio in Nile perch and mukene in both Lake Nabugabo and Lake Victoria to determine the effects on its bone strength, density and growth.
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Canada |
2018-05-22 |
2021-05-22 |
Natural Sciences |
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Degree Award |
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Joel HARTTER Nathan
ID:
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Population, Environment, and Climate in the Albertine Rift
REFNo: NS37ES
To Determine how coupled climate and anthropogenic landscape change impacts the dynamics and resilience of a protected areas and the surrounding human population, including impacts to human and wildlife health, food security, and governance.
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USA |
2018-05-18 |
2021-05-18 |
Natural Sciences |
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Non-degree Award |
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Fiona Cresswell
ID:
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High dose oral and intravenous rifampicin for adult tuberculous meningitis: an open-label phase II randomised controlled trial
REFNo: HS136ES
1. To determine whether higher-dose rifampicin, delivered orally at 35mg/kg/day or delivered intravenously at 20 mg/kg/day (for 2-weeks, followed by orally at 35 mg/kg/day for 6-weeks) provide equivalent plasma and CSF exposures, and whether the exposure profiles are favourable compared to the standard dose oral rifampicin. The pharmacokinetically optimal dose and route of administration of rifampicin can then be taken forward into a phase III clinical trial.
2. To observe whether greater rifampicin exposure in CSF is associated with any clinical benefit including more rapid resolution of coma, reduced neurocognitive deficit or reduced mortality.
3. To determine the diagnostic accuracy of Xpert MTB/Rif Ultra for TBM (ancillary study 1)
4. To describe the concentration of rifampicin in brain tissue in each treatment arm (ancillary study 2)
5. To explore the use of bedside ultrasound as a monitoring tool to improve supportive care for people with TBM (ancillary study 3)
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UK |
2018-05-15 |
2021-05-15 |
Medical and Health Sciences |
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Degree Award |
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Moses Ocan
ID: UNCST-2020-R014731
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Antimalarial resistance in Sub-Saharan Africa: Assessing spread of artemisinin resistance and chloroquine resistance reversal among Plasmodium falciparum parasites
REFNo: HS168ES
1) To determine through a systematic review, the extent of chloroquine resistance reversal among Plasmodium falciparum parasites in malaria endemic countries since the change in policy
2) To determine the association between four (4) most reported K13 gene polymorphisms in Sub-Saharan Africa and artemisinin susceptibility among Plasmodium parasites
3) To predict using a model the spread to Sub-Sahara African (Uganda) Plasmodium falciparum parasite population of the K13 propeller gene polymorphisms detected in Southeast Asia and associated with artemisinin resistance
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Uganda |
2018-05-15 |
2021-05-15 |
Medical and Health Sciences |
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Degree Award |
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