Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Dinah Amongin
ID: UNCST-2020-R014663
 An exploratory, mixed-method study of family planning self-care in Nepal, Niger, and Uganda
REFNo: HS2117ES

1. To explore perceptions of FP self-care among women of reproductive age (15-49 years) and men age 18 years and above. 2. To describe FP self-care behaviors and preferences among women of reproductive age (15-49 years) and men age 18 years and above. 3. To examine provider perspectives on FP self-care
Uganda 2022-04-20 2025-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 Effect of maternal exposure to air pollution on birth weight outcomes: A cohort Study among Urban Communities in Wakiso District, Uganda
REFNo: HS2141ES

To describe the association between maternal exposure to air pollution and pregnancy complications of antepartum haemorrhage and pre-eclampsia.,To describe the factors associated with the levels of PM 2.5 personal exposure among pregnant women in Urban Communities in Wakiso District, Uganda,To describe the association between maternal air pollution exposure (PM 2.5 and birth weight of their babies.,To assess the effect of maternal exposure to particulate matter on birth outcomes in Urban Communities in Wakiso District, Uganda,
 Uganda 2022-04-20 2025-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janepher Nyakake
ID:
Supporting young and female entrepreneurs for SME growth in Uganda and Somalia
REFNo: SS1256ES

To analyze the “potential impacts” of the interventions of these two innovation agencies on their supported SME clients to develop a package for rigorous evaluation.
 Uganda 2022-04-20 2025-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca PAHULJE Rose
ID:
Examining the northward shift in the distribution of African fishes in association with climate change
REFNo: NS345ES

To understand how climate is affecting the physiology and distribution of tropical fishes.

Specifically;
- To quantify the thermal limits and hypoxia tolerance of tropical fishes and the degree to which these limits are plastic
- To understand and predict how tropical fishes will respond to climate change – either via persistence in situ or changing their distribution by moving to more favourable thermal/oxygen regimes.
 Canada 2022-04-20 2025-04-20 Natural Sciences Non-Clinical Trial Degree Award
ALBERT KABANDA
ID:
Dry Rifting In the Albertine-Rhino Graben, Uganda (DRIAR)
REFNo: NS342ES

Objectives: A geophysical, geochemical, geological, and geodynamic investigation of the Albertine-Rhino Graben in western and northwestern Uganda to improve our understanding of continental rifting in areas where volcanic activity is minimal.
Uganda 2022-04-19 2025-04-19 Natural Sciences Non-Clinical Trial Degree Award
Susan Nakireka Tumwesigye
ID:
DETERMINANTS OF COVID-19 OUTCOMES IN UGANDA: A MULTICENTRE, MIXED-METHODS STUDY
REFNo: HS2090ES

Broad Objective
To describe the determinants of COVID-19 outcomes in Uganda
Specific Objectives
1.To describe the clinical characteristics and co-morbidities among patients hospitalized with COVID-19.
2.To determine the clinical outcomes (mortality, ICU admissions, length of stay) following hospitalization for COVID-19
3.To describe radiological patterns of COVID-19
4.To describe outcome of COVID-19 patients managed at home.
5.To explore the experience of patients managed with COVID-19 at home.
?

 Uganda 2022-04-19 2025-04-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gerald Mboowa
ID:
PATHOGEN DETECTION IN CHILDREN LIVING WITH HIV PRESENTING WITH NON-MALARIAL FEBRILE ILLNESS USING METAGENOMIC SEQUENCING AT BAYLOR-UGANDA
REFNo: HS2140ES

Primary objective: This project aims to utilise Shotgun metagenomic sequencing (sMGS) to comprehensively characterize microbial pathogens in Children Living with HIV Presenting with Non-Malarial Febrile Illness attending Baylor College of Medicine Children's Foundation –HIV treatment clinic
Secondary objectives:
1. To identify and characterize microbial pathogens in Ugandan children and adolescents living with HIV attending Mulago National Referral Hospital, Baylor-Uganda clinic with non-malarial febrile illness (NMFI)

2. To identify and describe the frequency of comorbidities in children with perinatally acquired HIV-infection with NMFI in Uganda
 Uganda 2022-04-19 2025-04-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Nahwera Loyce
ID:
EFFECTS OF 12-WEEKS AEROBIC DANCE ON BLOOD PRESSURE, PERCENT BODY FAT AND hs-CRP IN HYPERTENSIVE PATIENTS ATTENDING KYAMBOGO MEDICAL CENTRE, UGANDA
REFNo: HS2202ES

1. To establish the baseline systolic and diastolic blood pressure, percent body fat and hs-CRP levels in stage 1 hypertensive patients attending Kyambogo University Medical Centre in Kampala, Uganda.
2. To determine the effect of a 12-week aerobics dance programme on Systolic Blood Pressure (SBP) levels in stage 1 hypertensive patients attending Kyambogo University Medical Centre in Kampala, Uganda.
3. To determine the effect of a 12-week aerobics dance programme on Diastolic Blood Pressure (DBP) levels in stage 1 hypertensive patients attending Kyambogo University Medical Centre in Kampala, Uganda.
4. To establish the effect of a 12-week aerobics dance programme on percent body fat in stage 1 hypertensive patients attending Kyambogo University Medical Centre in Kampala, Uganda.
5. To determine the effect of a 12-week aerobics dance programme on hs-CRP levels in stage 1 hypertensive patients attending Kyambogo University Medical Centre in Kampala, Uganda.

Uganda 2022-04-19 2025-04-19 Medical and Health Sciences Clinical Trial Degree Award
Frederick GOGARTEN Jan
ID:
Comparing traditional monitoring of Kibale wildlife population abundance and health with molecular based environmental DNA based approaches
REFNo: NS343ES

To test the use of air DNA and fly-derived DNA for describing mammal and parasite communities by using the long-term monitoring efforts across transects in Kibale National Park.
Specifically aim to explore the role of flies in disease ecology in and around groups of primates in Kibale National Park, and their potential role as vectors at the human-wildlife interface, including the exploration of changes in fly density and disease prevalence.
Germany 2022-04-19 2025-04-19 Natural Sciences Non-Clinical Trial Non-degree Award
HAMEL Fortin Liana
ID:
Interaction between hypoxia and thermal tolerance in the cyprinid fish (Enteromius neumayeri)
REFNo: NS346ES

To look at the interaction between hypoxia (low oxygen) adaptation and thermal tolerance in tropical African fishes, of particular interest in Kibale National Park.

The project will specifically investigate how local adaptation to hypoxia affects the thermal and hypoxia tolerance of Enteromius neumeyari before and after acclimating fish to elevated water temperature
 Canada 2022-04-19 2025-04-19 Natural Sciences Non-Clinical Trial Degree Award
Matthieu Chemin
ID:
Lawyers for Consumer Protection: Evidence from a Field Experiment in Uganda
REFNo: SS1255ES

3.The UCC would be especially important in this context, as they serve as the telecom regulator for mobile money transactions. Furthermore, the UCC is currently developing plans for the creation of a “communications tribunal”, which is the ideal endpoint for those in the treatment group to have their disputes resolved.,2.This intervention would also be informative to consumer protection agencies simply so that they are made aware of both how prevalent the problem of mobile money fraud is, and how they can most effectively address it.,1.Findings of this intervention would be relevant to policymakers on several levels. First, conclusions from CTDR-U’s platform would be of utmost interest to regulators who are involved with fraud, especially when it relates to mobile money agent fraud such as in Buku and Mazer (2017).,
 Canada 2022-04-14 2025-04-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elisam Magara
ID:
PRESERVATION OF ORAL HISTORY IN THE MINISTRY OF THE WORD: BRIDGING EVANGELICAL GAP IN THE MARKETPLACE AMONG THE BANYANKOLE IN UGANDA
REFNo: SS1248ES

Purpose of the Study
Preserving of oral history restores the identity as one way to claim back the lost identity. As Marcus Garvey asserts, “a people without knowledge of the past history, origin and culture is like a tree without toots”. Therefore, careful effort is needed in assessment of oral history genres that best suits the ministration of the Word in the market place. This study aims at establishing strategies for applying Oral History in the Ministry of the Word in the Marketplace in Uganda.

Specific Objectives
This study shall be able to:
1. Establish the kind of oral history practices among the Banyankole available for the ministry of the Word.
2. Analyze the techniques in the ministration of the Word in the marketplace in Uganda.
3. Develop strategies for applying oral history in the Ministry of the Word for the Kingdom of God.

 Uganda 2022-04-14 2025-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
Sebastian Linnemayr
ID: UNCST-2021-R012696
 Goals for Adherence with Low-cost Incentives (GOALS)
REFNo: HS2207ES

The objective in year 1 is to identify the incentive design most effective for improving adherence.
The objective in year 2 is to maintain adherence improvements at the clinically optimal level of 90 percent and achieve viral suppression.
The objective in year 3 is to measure adherence for 12 months after the intervention ends to assess the impact of the different treatment arms on behavior change once incentives are withdrawn (persistence).

USA 2022-04-14 2025-04-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benon Zebosi
ID:
Factors associated with functional capacity and nutritional status among community dwelling elderly aged 65 to 85 in Lugazi municipality, Buikwe district
REFNo: SS1031ES

1. To assess the nutritional status of the elderly persons aged 65 to 85 in Lugazi municipality, Buikwe district.
2. To assess the functional capacity of the elderly persons aged 65 to 85 in Lugazi municipality, Buikwe district.
3. To investigate the association between functional capacity and nutritional status of the elderly persons aged 65 to 85 in Lugazi municipality, Buikwe district.

 Uganda 2022-04-13 2025-04-13 Social Science and Humanities Non-Clinical Trial Degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
 Alternative Dosing And Prevention of Transfusions (ADAPT): A prospective study to reduce transfusion requirements for children with sickle cell anemia using pharmacokinetics-based hydroxyurea dosing
REFNo: HS2093ES

Primary Objective • To compare the rates of blood transfusions overall and by specific indications in children with sickle cell anaemia (SCA), prior to and during hydroxyurea treatment Secondary Objectives • To determine clinical and laboratory factors associated with reduction in blood transfusions for children with SCA on hydroxyurea treatment
• To assess the feasibility and safety of a pharmacokinetic (PK)-based hydroxyurea dose within the predicted treatment range for Uganda
• To quantify rates of SCA-related complications (including stroke, sepsis, and pain) in participants receiving PK-guided hydroxyurea dosing and within the overall cohort on hydroxyurea treatment

 Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
 Adherence to Malaria Treatment Guidelines among Health Care Workers in Private Health Facilities in Kampala’s informal Settlements, Uganda
REFNo: HS2161ES

To explore barriers and facilitators towards malarial treatment guidelines among HCWs in private health facilities,To assess the factors associated with adherence to malaria treatment guidelines among HCWs in private health facilities,To establish the level of adherence to malaria treatment guidelines among HCWs in private health facilities,To assess adherence to malaria treatment guidelines and associated factors among HCWs in private health facilities in Kampala's informal settlements, Uganda,
 Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rachel Nankanja Babirye
ID:
FIGO/AOGU Advocacy for the Prevention of Maternal Mortality and Morbidity in Uganda (APMM) due to unsafe abortion –end evaluation of a three years’ multi-country capacity building project
REFNo: SS1249ES

1. To document the results and achievements achieved by FIGO and the member societies
2. To analyse the contribution of the project in strengthening the societies and the results achieved
3. To assess the project implementation by FIGO and the member societies, including lessons learned.
4. To extract lessons learned – “understanding enabling and hindering factors in advocacy for CAC, including safe abortion within the context of the law”

 Uganda 2022-04-13 2025-04-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Enhancing prediction of adverse pregnancy outcomes in Africa through partnerships and innovation
REFNo: HS2195ES

4. Calibrate the intersection between socio-epidemiological, clinical and laboratory parameters of the GOS using artificial intelligence.,3. To generate a resource of data and biological samples to facilitate hypothesis driven and discovery based approaches to identifying novel predictors and/or mechanisms of pre-eclampsia and the other GOS. ,2. To determine the positive predictive value of screening using biomarkers (soluble Flt-1 and placental growth factor) and serial ultrasound for the different adverse pregnancy outcomes in (1) above.,1. To determine the exposures (epidemiological, social, demographic, clinical, laboratory) linked to the different outcomes - pre-eclampsia, stillbirth, preterm birth and fetal growth restriction.,To enhance prediction of adverse pregnancy outcomes in Africa through partnerships and innovation,
 Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jörg Wiegratz
ID:
Changing the game: The dynamics of the commercialisation of football in Eastern Africa
REFNo: SS1246ES

This project is a comparative study of the ongoing and intensifying dynamics of commercialisation of football in East Africa. The aim is to empirically investigate and map the major drivers, characteristics and repercussions (also in terms of development of football, i.e. professionalism, performance, club management, fan experience, popularity etc.) of the commercialisation in two countries: Kenya and Uganda. It aims to capture stakeholders’ experiences, insights and views concerning commercialisation of football. The overall question is: what changes are triggered by the commercialisation of local football? I will talk to various stakeholders and gain some insights into developments at different clubs and commercial developments in Kampala/the country. These case studies will allow me to explore the dynamics of introducing cutting-edge commercial models in sports leagues on a continent that has had – compared to other regions – relatively low levels of commercialisation until recently. This will enable a better understanding of commercialisation-in-practice – and respective similarities and differences across the two sites - in a key football region in the Global South. The findings will inform relevant public/policy debates in the two countries, the region generally and beyond (e.g. at global level) regarding various aspects of the commercialisation of soccer. The study will contribute to the relatively nascent literature on commercialization in Africa generally. It will also draw lessons regarding commercialisation processes and issues that might be applicable to other countries in Africa and beyond.
 Germany 2022-04-12 2025-04-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julius Magala
ID:
Using Data to Catalyze Energy Investments
REFNo: SIR98ES

Main Objective: The overarching goal is to provide improved data on demand for productive energy use across Uganda to inform future actions/investments by the Ugandan Government as well as other stakeholders.
Specific Further Objectives: Our methods will capture data related to agricultural conditions and practices, complemented by spatial analysis. Respondent interviews will focus primarily on cropping and irrigation seasonality. These will be used in combination with numerous field observations (taken without interviews). Finally, the outputs of the CWP effort will emphasize statistical analysis and machine learning in order to make geospatial predictions, identifying areas where a combination of factors establish a higher probability for presence of and success in irrigation.

Uganda 2022-04-12 2025-04-12 Engineering and Technology Non-Clinical Trial Non-degree Award
Shelley Jones
ID:
COVID-19 as an urgent call for commitment to women's resilience and empowerment: A participatory action research project with vulnerable women in Uganda
REFNo: SS1207ES

The objectives of this project are to work with women in Uganda to develop and pilot a contextually- and culturally-responsive Resiliency and Empowerment Framework (REF) that will foster a community of support that encourages women to self-inventory their skills, knowledge, abilities, and experiences as well as identify and access resources they require to exercise empowerment and work collectively to transform their societies. The REF will be adaptable for women living in diverse contexts throughout the world. As part of REF, participants will create and implement their own, personal multi-stage Resiliency and Empowerment Plans (REPs) that will reflect their own aspirations. These REPs may represent individualistic or collaborative trajectories.
Canada 2022-04-12 2025-04-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Impacts of Covid-19 on Provision of Essential Healthcare Services and on Community Networks in Uganda
REFNo: HS2181ES

General Objective
To evaluate the Impact of COVID-19 on provision of essential Healthcare services and on the community networks in Uganda
Specific objectives
1. To determine the Impact of COVID-19 on essential health service delivery in Regional Referral Hospitals in Uganda.
2. To evaluate the actual local activities and collaboration of key stakeholders involved in CES in response to COVID-19 pandemic Uganda.


 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 A Randomized, Double-Blinded, Placebo-Controlled, Phase III, Clinical Trial of SARS-CoV-2 Vaccine, Inactivated (Vero Cell) in Adults Aged 18 Years and Above
REFNo: HS2185ES

Safety: To evaluate adverse events from the first dose and the booster dose to Day 28 after the whole-course immunization and serious adverse events from the first dose and the booster dose to at least 12 months after the whole-course immunization,Efficacy: To evaluate the efficacy of the SARS-CoV-2 Vaccine, Inactivated (Vero Cell) for symptomatic and laboratory-confirmed (RT-PCR method) COVID-19 cases caused by different SARS-CoV-2 variants,Immunogenicity: To evaluate the immune persistence of the investigational vaccine,Immunogenicity: To demonstrate the consistency of 3 lots of investigational vaccine in terms of GMT 14 days after the whole-course immunization,Immunogenicity: To evaluate the levels of neutralizing antibody and IgG antibody against SARS-CoV-2 14 days after the whole-course and after the booster immunization,Efficacy: To evaluate the efficacy of the SARS?CoV?2 Vaccine, Inactivated (Vero Cell) against symptomatic and laboratory-confirmed (RT?PCR method) severe COVID-19 disease,Efficacy: To evaluate the efficacy of the SARS?CoV?2 Vaccine, Inactivated (Vero Cell) after at least one dose, 2 doses, and after the booster dose of immunization,To evaluate the efficacy, safety and immunogenicity of the SARS?CoV?2 Vaccine, Inactivated (Vero Cell) in adults aged 18 years and above after a 2-dose schedule, and after booster vaccination,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Clinical Trial Non-degree Award
Aloysius Ssennyonjo Ssennyonjo
ID: UNCST-2021-R013504
 Evaluating the Impact of the Health Sub-District Strategy on Maternal and Neonatal Health Outcomes in Uganda (2000-2020)
REFNo: HS2169ES

4.To examine lessons learnt, opportunities and recommendations for optimizing the impact of HSD strategy on and health system performance (MNH) in Uganda,3.To explore the mechanisms through which the HSD strategy (and its adaptions) impacted maternal and neonatal health (MNH) outcomes,2.To determine the impact of the HSD strategy on MNH outcomes in Uganda over time and across geographical settings. a)To describe the trends in key health system performance indicators (focusing on MNH) over the same time frame. b) To determine the associations between the HSD strategy and health system performance (MNH outcomes) ,1. To explore how the HSD strategy evolved from 2000 to 2020 and why? a) To describe the critical timelines of the evolution of the HSD strategy. b)To analyze the processes, mechanisms and dynamics that explain the evolutionary process of the HSD strategy,To analyse the impact and underlying mechanisms of the health sub-district strategy on maternal and neonatal health (MNH) outcomes in Uganda from 2000 to 2020. ,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
 REDUCTION OF MATERNAL AND PERINATAL MORTALITY DUE TO PRE-ECLAMPSIA & ECLAMPSIA
REFNo: HS1473ES

OBJECTIVES

1. To conduct a needs assessment on the management of mothers with pre-eclampsia in select Health centre IIIs, IVs, District Hospitals, Regional Referral Hospitals and National Referral Hospitals in greater Kampala and other regions of the country in the calendar year 2020.
2. To analyse data generated in objective 1with a purpose of getting scalable interventional framework on reduction of maternal and perinatal motility and severe morbidity due to pre-eclampsia and eclampsia
3. To address preventable maternal and perinatal mortality and severe morbidity due to pre-eclampsia and other HDP through implementing the pre-eclampsia interventional framework for a period of one year.
4. Propose key recommendations to the Ministry of Health on identified system challenges that are hindering the accelerated reduction of maternal and newborn morbidity and mortality due to pre-eclampsia

 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jessica Kakesa
ID:
Barriers and opportunities to safe abortion in humanitarian settings in Bidibidi Settlement, Uganda
REFNo: HS2130ES

The aim of this study is to describe the abortion experiences of women and girls living in humanitarian contexts, and to generate a representative estimate of the abortion incidence, rate, and ratio.
Democratic Republic of Congo 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Herbert  Ainamani ELVIS
ID:
Exploring parenting styles and children’s task accomplishments during mother-child interactions in southwestern Uganda
REFNo: HS2060ES

1. To assess different parenting styles employed by mothers living in both rural and urban settings of Southwestern Uganda.
2. To examine the association between multivariate factors and parenting styles among the mothers living in Southwestern Uganda.
3. To examine the association between parenting styles and accomplishment of different tasks by the children in Southwestern Uganda.

 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
 Smart Discharges for Mom & Baby: A cohort study to develop prognostic algorithms for post-discharge readmission and mortality among mother-infant dyads..
REFNo: HS2174ES

To identify gaps and opportunities during in-hospital, discharge, and post-discharge care to inform the future development of an evidence-and risk-based bundle of interventions to improve postnatal care (PNC) for dyads.,To inform the development of an integrated maternal and newborn risk-based post-discharge care program.,To develop and internally validate clinical risk prediction models for identifying dyads at high-risk of death or hospital readmission in the 6 week post-delivery post-discharge period.,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annet Nakaganda
ID:
Vaginal stenosis in patients treated with Radiotherapy for cancer of the cervix in Uganda
REFNo: HS2150ES

To assess the incidence, risk factors and clinical manifestation(s), of radiation-induced vaginal stenosis in patients with cancer of the cervix at Uganda Cancer Institute.
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Arineitwe Kibonire Arineitwe Kibonire
ID:
Strategies to enhance indigenous men’s support for utilisation of long-acting reversible contraceptives amongst rural women in Uganda
REFNo: HS2152ES

The objective of this study is to:

•Explore and describe the perceptions of rural indigenous Ugandan men regarding the use of LARCs.

•Understand the belief systems that rural indigenous Ugandan men have regarding the use of LARCs

•Develop strategies to enhance indigenous Ugandan men’s support for utilisation of LARCs amongst rural women in Uganda

 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 A Study to Improve Understanding of Viral Load Suppression in Children Living with HIV in Uganda.
REFNo: HS2188ES

To establish factors associated with viral load suppression in children 0-14 years using the LIMS.,To determine the extent to which viral load suppression rates differ by demographic characteristics (age group, ART regimen, duration on ART, and region) using Laboratory Management Information System (LIMS) data.,To determine the trends in paediatric (0-14years) viral load suppression rates from 2016 to 2020.,To determine the proportion of children aged 0-14 years living with HIV that underwent a viral load test in 2016, 2017, 2018, 2019 and 2020 and are virally suppressed.,
 Uganda 2022-04-07 2025-04-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hellen Nabayiga
ID: UNCST-2022-R011299
 modelling the antibiotic supply chain. A case of Uganda
REFNo: SS1240ES

To develop an understanding of appropriate antibiotic availability in Uganda public health facilities
 Uganda 2022-04-07 2025-04-07 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Investigating the Relationship of Low-HDL as a Risk Factor for Development of Rheumatic Heart Disease
REFNo: HS2085ES

General Objective;
The objective of this project is to explore the relationship between Rheumatic Heart Disease (RHD) and high-density lipoprotein cholesterol (HDL-c) levels in a high risk pediatric population in Uganda.

Specific Objectives;
1)To evaluate whether or not low HDL-c is associated with the diagnosis of RHD.

2)To evaluate whether a lower HDL-c level is associated with more severe RHD.

 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Kutensa
ID:
Health care workers\' and mothers\' perspectives on the experiences and challenges with maternal health care services in rural areas of Uganda during the COVID-19 pandemic. A qualitative study.
REFNo: HS2134ES

1. To explore the mothers’ experiences and challenges with utilization of maternal health care services during COVID-19.

2. To explore health care providers’ perspectives and challenges regarding the delivery and mothers’ use of maternal health care services during COVID-19
 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Degree Award
twinamasiko nelson
ID: UNCST-2021-R013346
 MULTIDRUG RESISTANT BACTERIA CONTAMINATION OF CLINICAL ATTIRE OF MEDICAL DOCTORS IN MULAGO NATIONAL REFERRAL HOSPITAL.
REFNo: HS2177ES

Primary objective
1. To determine the prevalence of pathogenic bacteria on clinical attires of medical doctors in Mulago National referral hospital.
Secondary Objectives
1. To determine the prevalence of multidrug resistant bacteria on clinical attires of medical doctors in Mulago National referral hospital.
2. To determine the level of knowledge and attitudes on IPC among medical doctors in Mulago National referral hospital.
3. To determine the level of practice of IPC measures among medical doctors in Mulago National referral hospital.

 Uganda 2022-04-04 2025-04-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damian Kajunguri
ID:
Assessing the effectiveness of alternative science education teaching methods during and after COVID-19 lockdown in Kigezi region, Western Uganda
REFNo: SS928ES

The main objective of the research is to determine how the different learning approaches impacted science education during and after COVID-19 induced lockdown. The specific objectives are to: i) Establish the type and extent of coverage of the science-based learning that took place during and after lockdown. ii) Determine how practical aspects were handled in the alternative learning processes that were provided during and after lockdown. iii) Ascertain the uniformity of syllabus coverage of science subjects before-during- and after lockdown. iv) Assess students’ responses towards the various science-based learning processes during and after lockdown in respect of gender, age groups and school status.
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Michael Mutyaba
ID:
The Politics of Uganda's Refugee Policy
REFNo: SS1066ES

To investigate the political economy of the relationship between Uganda's refugee policy and its political system
To understand the needs, incentives and logics behind Uganda's liberal refugee policy
To examine how liberal Uganda's refugee policy is, compared with her neighbours Rwanda, Tanzania and Kenya
To explore the constraints that politic imposes upon the implementation of Uganda's refugee policy in the context of decentralisation
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Simplified Treatment for Eclampsia Prevention using Magnesium sulfate: A phase III, randomized, open label, active controlled, multicountry, multicentre, non-inferiority trial of simplified magnesium sulfate regimen for eclampsia prophylaxis (The STEP-Mag Trial).
REFNo: HS2076ES

The primary objective of this trial is to evaluate non-inferiority of magnesium sulfate 10g IM administered 12 hourly x 2 doses compared with a standard IV (Zuspan) or IM (Pritchard) magnesium sulfate regimen1 in the prevention of maternal eclamptic seizure.

The secondary objective of this trial is to evaluate superiority of magnesium sulfate 10g IM administered 12 hourly x 2 doses compared with a standard IV (Zuspan) or IM (Pritchard) magnesium sulfate regimen in the proportion of women experiencing adverse events indicative of magnesium toxicity.
 Uganda 2022-04-02 2025-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Patrick OJOK
ID:
Exploratory study on the implementation Status of inclusive education policies in Uganda
REFNo: SS1202ES

4. Identify and document best practices and lessons that can be up-scaled to improve the implementation of inclusive education in Uganda and at the sub-regional level (EAC). ,3. Explore the perceptions of education stakeholders in Uganda towards inclusive education and the appropriate model for implementing inclusive education.,2. Explore the facilitators and barriers to implementing inclusive education policies in Uganda.,1. Determine the implementation status of existing inclusive education policies in Uganda.,The purpose of the proposed study is to ascertain the implementation status of inclusive education policies in Uganda, explore the factors that influence their implementation and document best practices and lessons to reinvigorate inclusive education at a sub-regional level.,
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lydia Nakiyingi
ID:
Exploring immune mechanisms among persons with MTB infection or TB disease, compared to no MTB infection in an endemic setting
REFNo: HS2125ES

General objective:
•To understand the immune mechanisms that underlie TB infection and TB disease compared to those with neither state in an MTB endemic setting using samples collected from individuals with either latent or active TB infection and those without-MTB infection for comparison.
Specific objectives:
• To define the immunological mechanism(s) in MTB using samples from individuals with latent infection, active TB or no MTB infection.
•To identify correlates of immune protection against TB infection and disease in adults in high TB endemic settings; an important pre-requisite in responses to newer TB vaccines
•To compare genetic sequences between adults with active TB, latent TB and no MTB infection in order to delineate genetic mechanisms of protection or disease

 Uganda 2022-04-02 2025-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Teddy Nakubulwa
ID:
Sexual and Reproductive Health and Economic Empowerment –Supporting Out-of-school Adolescent girls’ Rights and Skills (SHE SOARS) Program
REFNo: SS1225ES

4) Identify programmatic priorities and approaches through key informant interviews with stakeholders such as government staff, community leaders, health care providers and staff from other sexual reproductive health rights projects.,3) Contribute to the evidence base surrounding Gender Equality and Sexual Reproductive Health outcomes for adolescent s through documenting evidences of how the project is rendering effective, relevant, efficient and sustainable solutions to target project participants. ,2) Examine the current knowledge, attitudes and practices related to sexual reproductive health and gender equality among adolescents, particularly out-of-school adolescents, to inform project implementation ,1) Establish baseline, mid term and endline values for all indicators for the SHE SOARS project.,
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ninsheka  Leonard
ID:
Analysis of the Effects of the Forms and Drivers of Urban Agriculture on the socio-Economic Status of Farmers in Kampala and Mbarara Cities, Uganda
REFNo: A172ES

1) Examine the forms of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
2) Examine the Drivers of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
3) Establish appropriate policy directions of urban agriculture on the socio-economic status
of urban farmers in Kampala and Mbarara Cities.
4) To establish the influence of socio-demographic characteristics on the socio-economic
status of urban farmers in Kampala and Mbarara Cities

 Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alinda  Fred
ID:
ADVANCING AGRICULTURAL INSURANCE IN UGANDA’S CLIMATE CHANGE ADAPTATION: DETERMINANTS AND STRATEGIES FOR INSURANCE UPTAKE
REFNo: A181ES

1. To assess the agricultural insurance positioned in the climate change adaptation framework for Uganda and what are the critical gaps
2. To assess the demand and supply side constraints to adoption of agricultural insurance in Uganda borrowing insights from empirical literature in other countries
3. To identify the existing strategies to promoting agricultural insurance as an overarching climate change adaptation strategy.
4. To identify strategies that Uganda can adapt to effectively promote agricultural insurance as a climate change adaptation strategy.

Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alfred Jatho
ID: UNCST-2021-R011710
 Barriers to and Facilitators of Prostate Cancer Screening among Men in Uganda Prisons
REFNo: HS2128ES

The goal of this study is to examine the perceptions, attitudes and beliefs of men in Uganda Prisons regarding barriers to and facilitators of PCa screening. This will enable the research team to identify potential interventional strategies to promote PCa screening among men in Uganda prisons.,
 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Optimizing the use of SARS-Cov-2 antigen rapid diagnostic tests (Ag-RDT) for timely detection and effective response to COVID-19 in key border communities in Uganda
REFNo: HS2050ES

To evaluate the feasibility of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

To determine the yield of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in the border districts of Tororo and Busia districts

To assess the acceptability of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
helen harrison
ID:
A grounded theory epistemological exploration of wellbeing for women with lived experience of conflict-affected trauma, based in Uganda
REFNo: HS2148ES

- To use thematic-induced analysis to develop a theory relating to the epistemology of wellbeing that is grounded in the interview data,- To conduct semi-structured interviews with six – eight female participants from each of the communities.,- To explore the epistemology of wellbeing for women from three specific Uganda-based communities, each of whom has lived experience of conflict-affected trauma, and who are linked through trauma counselling,
 UK 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 Diabetes in African Youth: Improving Glucose Time-In-Range (DAY Time) Randomized Clinical Trial.
REFNo: HS2129ES

Primary Study Objectives
1. To determine if patient ability to continuously observe plasma glucose levels for 6 months using a flash intermittently scanned CGM improves glucose TIR compared to baseline. The change in glucose TIR while wearing the unblinded CGM will be compared to change in TIR in patients performing 3x/day SMBG (wearing a blinded CGM for endpoint measurement).
2. To perform a cost analysis on flash glucose monitoring compared to 3x/day SMBG, to determine whether this technology is cost effective in the setting of a low-resource nation.
Secondary Objectives: To assess the change-from-baseline impact of unblinded CGM on:
1. Percent time-in-range at 12 months
2. Percent time with glucose 180-250, >250, <70, and <54 mg/dl at 6 and 12 months
3. HbA1c at 6 and 12 months
4. Patient satisfaction and quality of life at 6 and 12 months
5. Glucose variability (coefficient of variation, CV) at 6 and 12 months

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Performance evaluation of the CheckNOW™ HIV Self-Test study
REFNo: HS2170ES

1. To evaluate the performance (Sensitivity and specificity) of the CheckNOW™ HIV SELF TEST when compared to the Genscreen ULTRA HIV1/2 Ag/Ab EIA followed by the Murex diasorin HIV1/2 Ag/Ab combination (reference testing) in the laboratory and the national testing algorithm.

2. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the professional users, when compared to the reference testing and the national testing algorithm.

3. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the lay users, when compared to the reference testing and the national testing algorithm.

4. To assess the accuracy of the lay user interpretation of the HIVST result. This will be compared with the interpretation by the RA.
5. To assess the usability of the CheckNOW™ HIV SELF TEST. The usability of the test will be evaluated by questionnaires completed by the study staff observers and by the lay users.



Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Clinical Trial Non-degree Award
Samson Okello
ID: UNCST-2019-R001580
 Epidemiology of cardiac dysfunction in sub-Saharan Africa: Heart Failure Registry of HIV-infected and HIV-uninfected persons in Uganda and Zambia
REFNo: HS788ES

1. To describe the clinical characteristics, treatment outcomes, and predictors of all-cause and CV mortality among HIV-infected and HIV-uninfected heart failure adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
2. To describe echocardiographic etiology of heart failure among HIV-infected and uninfected adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
3. To determine the differences in the serum markers of cardiac fibrosis, cardiac injury, oxidative stress, and hypercoagulability in HIV-infected and HIV-uninfected individuals hospitalized with heart failure at Mbarara Regional Referral Hospital and the University of Zambia Hospital.

 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-degree Award
Jennifer Ross
ID:
Modeling Approaches to Prioritize TB Prevention in Uganda
REFNo: HS1981ES

1. Estimate national, regional- or district-level patterns in prevalence, incidence, and mortality of TB and TBHIV using a geospatial model to identify geographic areas with higher versus lower infection burden.

2. Quantify the potential impact in disease burden and cost for PT scale-up in regionalized versus uniform implementation.

3. Engage stakeholders to inform model development and evaluate strategies to improve the acceptability and feasibility of modeled strategies for TB prevention.

 USA 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Utility of using C - reactive protein (CRP) in identifying bacteremia in children below five years presenting with fever at the Kawempe National Referral hospital.
REFNo: HS2038ES

1. To assess the performance of CRP in identifying bacterial infection among children less than 5 five years presenting with fever Kawempe National Referral Hospital
2. To assess the performance of Neutrophilia in identifying bacterial infection among children less than 5 five years presenting with fever Kawempe National Referral Hospital
3. To compare the two diagnostic criteria in identifying children with bacteremia at Kawempe National Referral Hospital

 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET NANKYA
ID:
Toward effective community engagement for genomics research in Uganda
REFNo: SS1172ES

1. To assess Genomics Researchers’ perspectives and practices on CE for genomics research in Uganda.
2. To explore Community Stakeholders’ experiences and perspectives on CE for genomics research in Uganda.
3. To assess research regulators’ perspectives on what constitutes effective community engagement for genomics research in Uganda.
4. To develop a framework for effective community engagement for genomics research in Uganda.

 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Non-Clinical Trial Degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
 Development and validation of a Medical Internship Experience Scale (MIES) for low- and middle-income countries.
REFNo: HS2062ES

4.2 General Objective
To develop and validate the Medical Internship Experiences Scale in Uganda, so as to contribute to the understanding of internship experiences for the health workforce in low- and middle-income countries.
4.3 Specific Objectives
1) To draft a Medical Internship Experiences Scale (MIES) for testing in Uganda alongside other LMICs.
2) To develop and test the Medical Internship Experiences Scale (MIES) among intern doctors in Uganda.
3) To evaluate the experiences of intern doctors and 3-year post internship doctors with their medical internship, using the MIES in Uganda.
4) To explore the perceptions of intern doctors, and intern doctor supervisors regarding the wellbeing of intern doctors during the medical internship training in Uganda.

UK 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANITA ARINDA
ID: UNCST-2020-R014158
 AN EDUCATION PROGRAM FOR IMPROVEMENT IN HIV KNOWLEDGE FOR ADOLESCENTS WITH INTELLECTUAL DISABILITY IN ENTEBBE, UGANDA
REFNo: HS2159ES

To estimate the retention of HIV knowledge and change in attitudes to HIV of adolescents with mild-to-moderate ID at 3 months following an HIV education program.,To estimate the change in HIV knowledge and attitudes of adolescents with mild-to-moderate ID following an HIV education program education intervention.,To determine the feasibility and acceptability of the HIV education program for adolescents with mild-to-moderate intellectual disability in Entebbe.,To conduct a pilot study of an HIV education intervention program for adolescents with mild-to-moderate intellectual disability (ID) and to assess its feasibility, acceptability and ability to increase HIV knowledge at baseline and 3 months.,
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
 Understanding the Strategies, policies and stakeholders perspectives on air quality management: towards improving air quality pollution in urban settings in Uganda.
REFNo: HS2097ES

To conduct a scoping review to synthesize air quality management strategies in Africa with a focus on who is involved, what works and why.

To assess the knowledge and perspectives of stakeholders whose roles influence air pollution and related health outcomes in Kampala and Jinja Cities.
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bukenya Fred
ID:
Evaluation of a Public-Private Partnership project of indoor residual spraying on malaria prevalence in urban slum areas of Kampala
REFNo: HS2099ES

To evaluate the effectiveness of the PPP project vector control strategies (IRS) on: 1. malaria prevalence 2. trends in catchment area health facility malaria burden indicators (e.g. test positivity rates, proportion of malaria outpatient visits) before and after implementation of IRS in 8 urban/slum areas.
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominic Bukenya Yiga
ID:
Comparison of perceptions of diabetes amongst Ugandans with low and high BMI: a qualitative study
REFNo: SS1200ES

i)To describe the perceptions of the causes of the diabetes and impact of the
condition in both rural and urban populations
ii) To compare and contrast the views of those with low BMI and high BMI
iii) To develop an understanding of the interactions between patients and their
healthcare providers and whether the information provided differs in relation
to their location and BM
The overall aim of this study is to investigate perceptions of diabetes amongst Ugandan
adults with type 2 diabetes with and without obesity, and those living in rural and urban
locations
 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Ndungutse
ID: UNCST-2022-R011044
 BURDEN OF PNEUMOCOCCAL DISEASE AMONG CHILDREN BELOW FIVE YEARS OLD FOLLOWING PNEUMOCOCCAL CONJUGATE VACCINATION: ANALYSING LOCAL SURVEILLANCE DATA IN UGANDA
REFNo: HS2102ES

The project’s overall Goal is: To contribute to the understanding of the morbidity, mortality and disability due to Pneumococcal Disease among children below five years in Uganda. The project objectives;
1. Document the burden of pneumococcal disease (invasive and non-invasive) in under 5years old children in Uganda
2. Identify and determine the distribution of the pneumococcal serotypes in under-5yrs old children and the risk factors before, during and after PC Vaccination rollout in Uganda
3. Establish the PVC coverage rates by reviewing data pertaining vaccination and adverse events following immunization (AEFI) through using the available data source documents and reporting mechanisms.
4. Document the gaps in the surveillance data that need further intervention by comparing data available with standard case definitions

Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4Stronger Families: Addressing Child Behavioral Health by Strengthening Financial Stability and Parenting among Families in Uganda
REFNo: SS1205ES

The study examines the mechanisms by which economic empowerment (EE) and family strengthening (FS) interventions targeting social, familial and context-specific drivers affect childhood behavioral health.

Specific aims of the study are:

Aim 1: Examine the impact of EE only, MFG-based FS only, and combined EE+MFG-based FS on children’s DBD symptoms and behavioral functioning.

Aim 2: Test the influence of EE only, MFG-based FS only, and combined EE+MFG-based FS on family financial stability (e.g., food and housing stability, material assets, savings), parenting and protective family
processes (e.g., family organization, caregiver/child interaction, cohesion, support) and perceptions related to
help seeking (e.g., stigma) on CBH and functioning; and assess whether these change mechanism mediate intervention effects on DBD symptoms and behavioral functioning, and explore moderation by context specific moderators of intervention effects.

Aim 3: Qualitatively examine participants’ experiences with each intervention arm.
 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Clinical Trial Non-degree Award
Julian Bagyendera Kobutungi
ID:
Endline Survey of the Education Response Plan for Refugees and Host Communities (ERP)
REFNo: SS1234ES

Establish inclusion and contextualization of the impact level indicators, as assessed through baseline 2.0 for which data was collected in March 2021.,vi. Assess percentage of teachers that have the professional competency required for implementing the programme ,Identify opportunities to improve both the cooperation and coordination between the key stakeholders and their support aimed at the improved delivery of the education services in a set of concrete and actionable recommendations. ,Identify lessons and good practices from the implementation of the ERP I. ,Assess the sustainability of the results achieved by the ERP at national and district levels.,ii. Assess the effectiveness and efficiency of the implementation of the ERP at national and district levels; also, but not exclusively, with regard to: - Achievements of the Plan regarding increase access to education, improve quality of education for both refugee and host community children. - Strengthening of the national and district systems for effective delivery of education services considering the COVID –19 impact. - Assess the extent to which issues of gender equality, and equity have been taken into consideration. Special attention will be given to learners with disabilities from both the refugee and host communities to ensure that access to school, teacher’s capacity (training, capacity to identify needs they may have, materials) and identification methods are assessed during the evaluation. ,i. Assess the relevance and coherence of the objectives and the approach of the ERP at national and district levels.,2) To assess and validate the results partners have achieved during the implementation period as a way to ensure and support accountability for ERP support. ,1) Provide information to support learning among key stakeholders from the experience of implementing the ERP at national and district levels, with a view to informing the ERP II and similar initiatives. ,
 Uganda 2022-03-29 2025-03-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
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