Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
owino ambrose
ID:
“Exploration of mathematics teachers’ pedagogical content knowledge for teaching subtraction strategy: A case study in Kwania District, Uganda”
REFNo: SS554ES

The purpose of this study is to explore mathematics teachers’ pedagogical content knowledge for teaching subtraction strategies.
 Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Richard Mugambe Kibirango
ID:
The impact of an mhealth and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area. A cluster randomised trial.
REFNo: HS882ES

1. To explore the opportunities for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
2. To explore the barriers for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
3. To compare the impact of mobile phone WASH text messages with that of environmental cues on hand hygiene practice among health workers in HCFs in the GKMA.

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Emma Ariyo S
ID:
Examination of Sociocultural Boundaries and Gender construction in Women’s Rugby in Uganda
REFNo: SS579ES

1. Contributing to the body of literature on women rugby players’ use of sport to navigate socio-cultural structures in society.

2. Providing an in-depth understanding of how female participation in sport impacts multiple identities [relations] and relationships [social positioning] in reference to young women and their families and communities.

3. Inform educators, activists, policy makers and sport administrators’ decisions about developing sport opportunities for women in Uganda.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Edith Akankwasa
ID:
Implementing a child disability prevention, detection and rehabilitation project in central Uganda: Learning and experiences from the field
REFNo: HS896ES

i. To establish if amongst the intervention districts, those districts that show stronger implementation of birth defect and child disability prevention, child disability detection, management and rehabilitation interventions as envisaged perform better on key birth defect detection and child disability rehabilitation indicators compared to those intervention districts with “a lower level of implementation” (i.e., evidence of “dose-response”).
ii. To determine if, after three years, districts in project overall intervention area will show more improvement in coverage from baseline on key birth defect and child disability prevention, disability detection, management and rehabilitation indicators compared with those districts in the comparison area.
iii. To appraise the processes used in enhancing the delivery of the birth defect and child disability prevention, detection and rehabilitation services where they are being implemented.
iv. To explain in detail how and why the strategies employed led to the observed coverage in access to and utilization of the CDR project services in the implementation districts.
v. To characterize the stakeholders for birth defect and child disability prevention, detection and rehabilitation services.
vi. To document the barriers and facilitators used in the implementation of the CDR project along with how the barriers can be addressed

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
WINTERS MUTTAMBA
ID:
Exacerbation of Chronic Bronchial Sepsis (ECBS): A study of the role of key bacteria in exacerbations of COPD and bronchiectasis
REFNo: HS921ES

SECONDARY OBJECTIVES
i. To compare bacterial loads at presentation with time to first exacerbation.
ii. To assess the relationship of bacterial loads of specific bacteria with emergency attendance.
iii. To compare bacterial loads at presentation with time-to-clinical-stability (TCS), CRP response and length of antibiotics.
iv. To assess the relationship of specific bacterial loads with quality of life (QoL) scores.
v. To assess the microbiome dynamics during- and after- treatment.

EXPLORATORY OBJECTIVES
1. To compare bacterial loads with Bronchiectasis Severity Index (BSI) in those with a clinical diagnosis of bronchiectasis.
2. To compare admission bacterial loads with baseline FEV for relationship with key clinical outcomes.
3. To compare key clinical outcomes based upon initial counts of neutrophils, lymphocytes, platelets and eosinophils, and their ratios (including principally neutrophil-lymphocyte ratio, NLR, and platelet-lymphocyte ratio, PLR).
4. To compare bacterial loads with bronchiectasis severity index (BSI) in those with a clinical diagnosis of bronchiectasis.


 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Reducing Tobacco use among the In- and Out-of-School youths in Moroto district, Uganda
REFNo: HS1021ES

General objective:
The general objective is to assess tobacco use among the youth in Moroto district.

Specific objectives:
1)Explore perceptions of tobacco use among youth in and out of school in Moroto district

2)Determine the factors associated with tobacco use among youth in and out of school in Moroto district

3)Describe the perceptions regarding tobacco use among the school teachers and administrators

4)Explore the cultural role that tobacco use plays in the lives of the youth in Moroto district.

5)Assess adherence to the tobacco control Act within bars and restaurants in Moroto district.

6)Assess youth access to tobacco in Moroto district.

7)Describe the perception of the implementation of tobacco control activities in Moroto district by enforcement officers.

 Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Shaheen Memon Mohamed Zahiruddin
ID:
APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES

1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.

Kenya 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
Harriet Opondo
ID: UNCST-2022-R010927
 Counselors’ Experiences of HIV Status Disclosure to Children living with HIV in Uganda
REFNo: SS626ES

-To explore subjective experiences of counselors during the process of status disclosure to children living with HIV
-To find out how counselors are prepared and trained to conduct status disclosure to children living with HIV.
-To establish the current interventions used by counselors in HIV disclosure process to children.
-To find out self-identified training needs of counselors during and after status disclosure to children living with HIV.

 Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
REFNo: SS632ES

Suubi4Stigma will address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV/AIDS-associated stigma and its negative impact on child health and psychosocial well-being. Specifically, the proposed study will examine two evidence-based interventions used in mental health settings, schools, and communities: 1) group cognitive behavior therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level; and 2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH and their families.

Aim 1: Pilot test the feasibility, acceptability, and preliminary impact of innovative G-CBT and MFG on reducing HIV/AIDS-associated (internalized and family-level) stigma and its’ impact on youth and family-level outcomes (stigma, trauma symptoms, depression, sexual risk, family/social support and adherence to medication) compared to: 1a) usual care vs G-CBT; b) Usual care vs MFG; c) G-CBT vs. MFG;

Aim 2: Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to G-CBT and MFG intervention implementation and participation.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Joseph Oloro
ID: UNCST-2024-R004525
 Toxicological study of the antimalarial remedy (Artavol®) and its flavonoid isolate from artemesia annua
REFNo: HS540ES

To determine acute toxicity of Artavol® and of its isolated flavonoids
ii. To investigate the sub-acute and sub-chronic toxicity potential of Artavol® and of its isolated flavonoids.
iii. To evaluate the effects of Artavol® and of its isolated flavonoids on the fetus.
iv. To examine the mutagenic potential of Artavol® and of its isolated flavonoids.

 Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Characteristics of persons screened, tested and diagnosed with corona virus disease-19 at health facilities in Uganda
REFNo: HS657ES

Main objective:
To estimate the cumulative incidence of a composite treatment outcome of admission to intensive care unit, mechanical ventilation or death among COVID-19 confirmed patients attending health facilities in Uganda for COVID-19 care.

Secondary objectives:
1. To describe the socio-demographic, behavioral and clinical characteristics of patients screened for and or receiving COVID-19 care at health facilities in Uganda
2. To determine the screening and testing outcomes of COVID-19 infections among patients at health facilities in Uganda

 Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 DECENTRALIZATION OF BENZATHINE PENICILLIN G BEST PRACTICES: BUILDING THE TOOLS FOR A SUSTAINABLE AND SCALABLE PROGRAM
REFNo: HS835ES

(1) Develop materials that can be used across Uganda and East Africa to strengthen BPG administration skills in the health worker community,
(2) Test this package of materials in Lira and Mbarara, areas with high BPG demands, and
(3) Evaluate the immediate and 3-month results of the educational program on proper BPG delivery, health worker comfort, and patient satisfaction.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Firminus  Mugumya
ID:
Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES

The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?

The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?

 Uganda 2020-11-25 2023-11-25 Social Science and Humanities Non-degree Award
Ronald Mulondo Mulondo
ID:
Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES

1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.

 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Benjamin Atwine
ID:
Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES

General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
 Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES

To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES

1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.

 Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Viola Karungi
ID:
Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES

The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?


Uganda 2020-11-23 2023-11-23 Social Science and Humanities Degree Award
Stella Neema
ID: UNCST-2019-R000814
 Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES

The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.

 Uganda 2020-11-23 2023-11-23 Social Science and Humanities Non-degree Award
DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES

a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
 Uganda 2020-11-23 2023-11-23 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

 Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
Barbara Mukasa
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES

(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS

 Uganda 2020-11-20 2023-11-20 Social Science and Humanities Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES

-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas

 Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
 Predictors of indoor air quality in Kisenyi-Mugunu a slum settlement in Fort Portal Municipality, Uganda
REFNo: HS695ES

General objective
To assess predictors of indoor air quality so as to promote the health of children under five dwelling in Kisenyi-Mugunu, Fort Portal Municipality.
Specific objectives
1. To determine the level of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
2. To establish the predictors of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
3. To explore the barriers and facilitators to uptake of healthier household energy options in Kisenyi-Mugunu.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Characterizing Determinants of Primary KSHV Infection among Children and Adolescents in Uganda
REFNo: HS735ES

1. To determine the incidence and to define the viral, immunologic, and clinical features of primary KSHV infection.
2. To identify the biologic and behavioral risk factors associated with primary KSHV infection.
3. To develop mathematical models that characterize KSHV shedding dynamics and virologic drivers required for transmission.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 Machine Learning and Secondary Data Analyses of the RASHOTS Database to Guide Clinical Decision Making and Predict Patient Prognosis at Kiruddu National Referral Hospital, Uganda
REFNo: HS745ES

The primary project objectives are:
1. To utilise ML methods to estimate the risk of mortality on the ID wards at Kiruddu National Referral Hospitals using the RASHOTS medical database
2. To develop prognosis prediction scores for survival on the ID wards using ML methods on the RASHOTS medical database based on clinical prognostic factors

The secondary project objectives are:
1. To estimate the prevalence of major mortality drivers such as tuberculosis, tetanus using the RASHOTS medical database
2. To create a prognosis prediction protocol for risk of tuberculosis related mortality as a computer application for use by clinicians on ID wards
3. To use the RASHOTS database for quality improvement in clinical care and practice in the department of Internal Medicine

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Annette Namugaya Mugabe Jane
ID: UNCST-2020-R014795
 TRENDS AND INDICATIONS FOR CAESAREAN SECTION IN MBALE REGIONAL REFERRAL HOSPITAL A CROSS SECTIONAL STUDY
REFNo: HS777ES

General Objective
To determine the trends and indications for caesarean section delivery in MRRH (Eastern Uganda) during the study period (July 2013 to June 2018)

Specific Objectives
1. To determine the trend for caesarean section in MRRH (Eastern Uganda) over the study period
2. To identify the indications for CS delivery in MRRH (Eastern Uganda) over the study period

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Next Generation Nutrition in Uganda: Enhancing Dietary Intake of Iron and Folic Acid in a Culturally Acceptable Food Product for Pregnant Women to Improve Maternal and Child Outcomes
REFNo: HS828ES

Evaluate the effect of the innovative product on the health outcomes of the infants at birth,Investigate the efficacy of this innovative product to reduce iron and folic acid deficiency in pregnant women.,Develop a culturally acceptable and quality assured iron bio-fortified beans and silverfish pre-cooked instant sauce fortified with iron and folic acid to meet nutritional needs for pregnancy.,
 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
 Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

 Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
 UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 “Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
 ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Jonathan Nsamba
ID: UNCST-2024-R003888
 Body composition and muscular health of children and adolescents diagnosed with type 1 diabetes mellitus in Uganda
REFNo: HS759ES

1. To determine the body composition of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
2. To determine the hand grip strength of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
3. To examine the associations between dietary intake patterns, physical activity, nutrition status and body composition among children and adolescents diagnosed with T1DM
4. To understand the perceptions of newly diagnosed Type 1 Diabetes Mellitus children and adolescents about their disease status, barriers and facilitators to self-care.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
FADHIL GERIGA
ID: UNCST-2022-R011524
 Optimizing Nephroblastoma treatment outcomes in Uganda
REFNo: HS822ES

Primary Objectives:
o To determine the one-year survival of children with pathology confirmed nephroblastoma treated with multidisciplinary, stage-based care in Uganda.
o Assess the factors associated with morbidity and mortality among children with nephroblastoma.

Secondary Objectives:
o Characterize the frequency and spectrum of other malignancies that present similar to Nephroblastoma
o Characterize the social needs and health literacy of nephroblastoma patients and their caregivers at the UCI
o Assess quality measures of a multidisciplinary care, including:
- Treatment timing benchmarks following guidelines developed for UCI
- Adherence to treatment plan and elimination of loss to follow-up
o Assess social needs and provide a patient navigator for families of children with nephroblastoma and reduce the non-clinical barriers to care for children with nephroblastoma

Exploratory Objectives:
o To collect plasma for future studies evaluating circulating tumor DNA as a tool for diagnosis of pediatric kidney cancers and monitoring of patients with nephroblastoma.
o Collect stool specimens for future studies to define baseline factors in the stool microbiome that are associated with neutropenic fevers, sepsis and 12 months survival using combination of sequencing methods and stool ova and parasites evaluation.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 EXPLORING CHILDREN’S UNDERSTANDING OF COVID-19 AND ITS PREVENTIVE STRATEGIES IN UGANDA: A CROSS SECTIONAL STUDY AMONG CHILDREN AGED 10-13 YEARS IN HOIMA DISTRICT
REFNo: HS830ES

General objective

To explore children’s understanding of COVID-19 disease and related preventive measures, in order to generate information that will guide the development of evidence-based strategies for strengthening and improving children safety and wellbeing during and after the COVID-19 crisis.

Specific objectives

1.To establish the children’s knowledge of COVID-19 transmission and its preventative measures in Hoima Municipal Council

2.To describe how the COVID-19 preventative measures are understood and practiced by children aged 10 to 13 years in Hoima Municipal Council

3.To explore the enablers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

4.To explore the barriers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Formative Study to Understand Drivers and Barriers to Uptake of Permanent Methods of Family Planning Among Men and Women in Busoga Sub region
REFNo: HS862ES

The overall objective is to understand the factors that influence women, men and providers in Busoga region during the journey to access PMs to enable PSIU to design interventions.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
NAUME MUYANGA
ID:
UNDERSTANDING THE IMPACT OF GENDER BASED VIOLENCE ON HIV/AIDS PREVENTION AND TREATMENT HEALTH SEEKING BEHAVIORS AMONG TRANSWOMEN IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA.
REFNo: SS557ES

Broad objective:
To understand the impact of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Specific objectives:
1. To document the lived gender-based violence experiences among the transwomen in the greater Kampala metropolitan area, Uganda.
2. To explore the existing gender-based violence referral pathways used by the transwomen in the greater Kampala metropolitan area, Uganda.
3. To explore the impacts of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Uganda.
4. To identify priority issues for advocacy and programming in prevention and response to gender-based violence among the transwomen in the greater Kampala metropolitan area, Uganda.

 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Susanna (Zanna) Clay
ID:
The origins of empathy- Investigating empathy development in the first two years of life
REFNo: SS596ES

Empathy – the sharing and understanding others’ emotions and thoughts – is an essential part of what it means to be human. While empathy underpins our most meaningful social interactions, we lack knowledge about its developmental and evolutionary origins. Thus far, research on empathy development remains limited, something which may have led to inaccurate conclusions that infants lack the capacity for empathy before their second year.. Although the view that infants lack empathy has recently been challenged, current research remains constrained by a lack of research attention as well as suitable methodologies to study early empathy. A key goal of this project is to address these limitations by conducting the first major study of empathy development across the first 2 years of life. By combining observations with novel experimental techniques our goal is study how the cognitive and affective components of empathy emerge.

Another objective is to investigate the impact that the social and cultural environment have on infant socio-emotional development. Research indicates that caregiving and the socio-cultural environment shape infant development, however, there is little research looking into how these factors shape empathy development. In addition, most developmental research so far has been conducted on infants from Western societies, also denoted as WEIRD (Western Educated Industrialised Rich Democratic) whilst ignoring cross-cultural variability. By focusing on a subset of Western societies, current developmental research is thus not representative of global diversity; ignoring insights from cross-cultural variation may lead to inaccurate interpretations.

In order to address this and understand how the socio-cultural environment shapes empathy development, it is essential to study how empathy develops in a more diverse cross-cultural sample. Through doing so, we can also address which aspects of empathy may be learned or socially-mediated, and which might reflect human universals. The current project aims to address this by studying the development of empathy and the influence of the socio-cultural environment. The capacity for empathy has far reaching consequences for how we function as a species and interact with others. A lack of capacity to care about others (empathy) can have many negative consequences for individuals and our societies, including reduced wellbeing, quality of social relationships, crime and mental health. Given the importance of empathy for our social and societal functioning, it is essential to know where empathy comes from and how it is shaped by social and cultural experiences.

This project represents a continuation and extension of the research activities of a current and approved research project, led by Professor Katie Slocombe, running on infant development in the Masindi district of Uganda. This project was approved by UNCST and UVRI (UVRI-045/2017). Our current project uses very similar methods and is planned to be conducted with the same local research assistants and communities who have participated in this research.

UK 2020-11-17 2023-11-17 Social Science and Humanities Degree Award
Kenneth Katumba Rogers
ID:
Developing a country-specific EQ-5D-5L value set and an inequality parameter for Uganda
REFNo: SS597ES

The primary objective of this study is to develop an EQ-5D value set for Uganda,

secondary objectives are:
● To explore the feasibility of a ‘lite’ valuation protocol in the LMIC setting
● To elicit a health inequality aversion parameter for Uganda
 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Understanding Self Injection of DMPA-SC: Provider Research Uganda 2020
REFNo: HS938ES

The study is aimed at gaining a deep understanding of the consumer and health care provider journey is critically important to the introduction of family planning products into new districts. through answering the following questions:
1. What is the value proposition of self-inject for them?
2. What would increase their level of trust in women’s ability to successfully self-inject?
3. What would enable them to support consumers on the self-injection journey?
o What would be included in an optimal consumer initial training experience?
o What factors would support them to provide ongoing support for consumers who inject at home and experience side-effects?
o How could they better help consumers overcome barriers to access, including ensuring stock of DPMA-SC for client’s re-supply of product?
4. What factors would optimize provider training for self-injection?
o How could training be more convenient, effective, and of higher perceived value?
o What are the opportunities and barriers to using digital channels to learn and attend training on self-inject?
o What are the opportunities and barriers to using digital channels to train and support clients in using self-inject?

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Theoretical analysis of the pediatric discharge process in Uganda: A process evaluation
REFNo: HS929ES

The primary objective of this study is to build a theoretical model of the current pediatric discharge pathway from the time of admission until post-discharge follow-up.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Co-infection of SARS-CoV-2 with M. tuberculosis & other respiratory pathogens (SARS-CoV-2-
REFNo: HS940ES

(1) Estimate the prevalence of coinfection of SARS-CoV-2 with other respiratory pathogens, (2) Investigate the impact of coinfections on molecular testing for COVID-19 infection and, (3) Apply metagenomics whole genome sequencing for unbiased detection of respiratory pathogens directly in respiratory samples
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 Rapid Assessment of COVID-19 Impact on Family Planning Access and Use
REFNo: HS952ES

1. Document the proportion of Viamo 3-2-1 users who have their demand for family planning satisfied by modern methods during the pandemic and the recovery process;
2. Measure the proportion of current modern contraceptive users who have obtained their preferred contraceptive method among women who initiated or resupplied their method during the pandemic and the recovery process;
3. Describe barriers in accessing family planning services to ensure voluntary method use and choice during the pandemic and the recovery process.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 International Registry of Healthcare Workers Exposed to COVID-19 Patients (UNITY Global) at Selected Health facilities in Uganda
REFNo: HS964ES

Primary Objective
To assess the association of potential prophylactic treatments with reduced risk of COVID-19 (or SARS-CoV-2 infection) in HCWs caring for COVID-19 patients at selected health facilities in Uganda.

Secondary objectives
i) To characterize the type of potential prophylactic treatments, by dose and duration, overall, and by region and or selected health facilities (sites) in Uganda.
ii) To explore the key factors (for example, use of PPE, HCW and healthcare facility characteristics, underlying co-morbidities, household history and COVID-19 exposure) modifying the risk of COVID-19 among HCWs at selected health facilities (sites) in Uganda.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
 Antibacterial activity of Rosmarinus officinalis L. and Curcuma longa against bacteria from clinical specimens in Uganda- A therapeutic option for multidrug resistant bacteria (ARC study)
REFNo: NS141ES

Main objective
To determine the activities of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts against bacteria isolated from clinical specimens at the Makerere University Microbiology Clinical Laboratory (MUCML) from January 2018 to December 2019

Specific objectives
1. To develop the chemical composition of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts
2. To determine the Minimum Inhibitory Concentration of plant extracts from Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) against bacteria isolated from clinical specimens
3. To determine the synergistic effects of combination of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) and antibiotics against bacteria isolated from clinical specimens in the MUCML
Uganda 2020-11-17 2023-11-17 Natural Sciences Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
 The Effect COVID-19 Pandemic on the Management and Control of Diabetes in Patients Receiving Support from a Life for a Child-Supported Diabetes Program in Kasese District, Western Uganda
REFNo: HS987ES

• To describe problems and challenges experienced by patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To explore personal experiences of health workers and primary caregivers regarding diabetes management and control of patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To document mechanisms used to solve problems and overcome challenges encountered by patients with insulin-requiring diabetes, caregivers and health workers during the COVID-19 pandemic.
• To describe the perceived support needs for patients with insulin-requiring diabetes during the COVID-19 pandemic period and post the COVID-19 period.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Interventions for Improved Post-partum ART Continuation and HIV Testing of Male Partners of Women in PMTCT B+ in Uganda
REFNo: HS991ES

Aim 1: To evaluate whether the proportion of male partners of pregnant HIV-positive women who test for HIV, is improved after distribution of a letter of invitation to a wellness visit (dual syphilis and HIV rapid test, blood pressure, visual acuity screening and COVID-19 screening) to their female partners compared to the standard of care (standard of care invitation letter from the clinic).

Aim 2: To evaluate whether POC viral load testing with same day ART adherence support improves viral suppression among pregnant and post-partum women living with HIV compared to standard of care lab-based HIV VL testing.

Aim 3: To assess the proportion of HIV-negative male partners who initiate PrEP and HIV positive men who initiate ART among male partners who test for HIV through a wellness visit or standard of care letter from the clinic.

Aim 4: To evaluate acceptability and preferences for HIV testing and other health services among pregnant women and male partners using mixed methods.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
EARLY RESUMPTION OF SEXUAL INTERCOURSE IN THE PUERPERIUM AMONG MOTHERS IN UGANDA: BURDEN AND THE EFFECT OF HEALTH EDUCATION ON PUERPERAL ABSTINENCE
REFNo: HS1050ES

1)To establish the burden and factors associated with of early resumption of sexual intercourse within the puerperium (ERSP) among new mothers in Kawempe National Referral Hospital (Kawempe NRH) and Mengo Hospital.
2)To explore the perceptions, attitudes, experiences and actions towards the ERSP among new mothers and their partners in Kawempe NRH and Mengo Hospital.
3)To explore how health care workers in Kawempe NRH and Mengo Hospital perceive the level of puerperal sexual health care services provided to couples with new babies.
4)To identify strategies that may delay the early resumption of sexual intercourse among new mothers at Kawempe NRH and Mengo Hospital and design an appropriate psycho-sexual educational intervention to reduce ERSP.
5)To evaluate the effect of psycho-sexual health educational intervention on reducing ERSP among couples with new babies at Kawempe NRH and Mengo Hospital.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
Joseph Musaazi
ID:
USING ROUTINELY COLLECTED SECONDARY DATA TO ESTIMATE UPTAKE AND EFFECT OF ISONIAZID PREVENTIVE THERAPY ON TUBERCULOSIS INCIDENCE AND PREGNANCY OUTCOMES AMONG PEOPLE LIVING WITH HIV RECEIVING CARE IN PUBLIC HEALTH FACILITIES IN UGANDA.
REFNo: HS729ES

1) To determine trends of IPT uptake and completion rates among PLHIV receiving HIV care at public health facilities in Uganda.
2) To determine the effect of IPT on TB incidence among PLHIV receiving care at public health facilities in Uganda.
3) To estimate the effect of IPT on pregnancy outcomes among women living with HIV (WLHIV) receiving care at public health facilities in Uganda.

 Uganda 2020-11-16 2023-11-16 Medical and Health Sciences Non-degree Award
Jamila Nansimbe
ID:
UNDERSTANDING THE MEDICAL SUPPLY CHAIN BOTTLENECKS IN THE PUBLIC HEALTH SECTOR IN UGANDA (CASE OF KAMPALA CAPITAL CITY AUTHORITY HEALTH CENTERS)
REFNo: HS939ES

1. To examine the main causes of stock-outs of medicine and health supplies.

2. To examine the main causes of expiry of medicines and health supplies.

3. To recommend supply chain interventions to improve availability of medicines and health supplies.

 Uganda 2020-11-13 2023-11-13 Medical and Health Sciences Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A5372: Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals
REFNo: HS624ES

Primary Objectives;

-To determine the dosing for DTG that, when given together with 1HP, achieves target exposures (Ctrough) of standard-dose DTG when it is given without RPT.
-To estimate the steady state plasma pharmacokinetics (PK) of DTG when DTG 50 mg is dosed twice daily (BID) with 1HP.
-If Arm 2 opens, to estimate the steady state plasma PK of DTG when DTG 50 mg is dosed once daily (QD) with 1HP.

Secondary Objectives;

-To evaluate the safety of coadministration of DTG based ART with 1HP.
-To evaluate the tolerability of coadministaration of DTG based ART with 1HP
-To estimate the proportion of participants who maintain virologic suppression when DTG based ART is coadministered with 1HP

 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Pauline Amuge Mary
ID:
Community-based initiation and delivery of isoniazid preventive therapy (IPT) among household TB contacts in Uganda: A pilot project in Southwestern Uganda. Short Title: Community-Based TB prevention (Acronym: COMBAT TB).
REFNo: HS768ES

Primary Objective:
To assess the uptake of IPT among household TB contacts <5 years of age receiving IPT in the community delivery approach.

Specific Objectives:
1. To determine IPT completion rates among household TB contacts <5years of age enrolled in community-based delivery approach compared to those in the health facility-based IPT delivery approach.
2. To identify the factors that facilitate or hinder IPT uptake in the community-based delivery for household TB contacts <5years of age.

3. To determine the feasibility of community-based IPT delivery for household TB contacts <5years of age.
4. To determine the factors that facilitate or hinder IPT completion among household TB contacts <5years of age who initiate IPT.


 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Denis Kyabaggu Senkandwa
ID: UNCST-2023-R005881
 INFLUENCE OF SP110 POLYMORPHISMS IN HUMAN MACROPHAGES ON PULMONARY TUBERCULOSIS DISEASE AMONG UGANDANS
REFNo: HS870ES

-To identify, using Next Generation DNA Sequencing (NGS) technology, the SP110 gene polymorphisms among adult Ugandan pulmonary tuberculosis (PTB) disease patients reporting to Mulago National Referral hospital TB clinic.
-To determine the effect of the commonest SP110 SNPs identified in Ugandans on in vitro infection kinetics of MTB as measured by confocal microscopy techniques, in human monocytic leukemia THP-1 macrophage tissue cultures.
-To determine the in vitro effect of the top 3 SP110 SNPs among Ugandans on infection kinetics of MTB lineages 2, 3, 4 and H37Rv isolates in human monocytic leukemia THP-1 macrophage tissue cultures using confocal microscopy.
-To determine the SP110 SNPs present among TB patients co-infected with HIV at Mulago National Referral Hospital TB clinic.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 PILOT OF A NETWORK-DRIVEN, ADVOCACY INTERVENTION TO PROMOTE CERVICAL CANCER SCREENING IN UGANDA
REFNo: HS943ES

The proposed intervention development study seeks to improve cervical cancer screening in Uganda by engaging and training local public health researchers and program implementers, and empowering women living with cervical cancer risk (WLCCR), defined as women who have ever received treatment for pre-cancerous or cancerous lesions, to advocate for CC screening and early treatment among women in their social networks. Specifically, the study will aim to: 1. Assess the feasibility and acceptability of implementing a cervical cancer screening advocacy intervention with WLCCR, who will be trained to be advocates for CC screening and treatment behaviors in their social networks. 2. Assess preliminary intervention effects on the CC screening (primary outcome) and treatment behaviors of women in contact with the WLCCR advocates and diffusion of anti-stigma messages across social networks. 3. Explore characteristics of women who more effectively engage in screening advocacy (in terms of socio-demographics, network characteristics, and type of social network members receiving advocacy). 4. Increase capacity among local researchers and program implementers to conduct public health research on cervical cancer control and use social network-based intervention and measurement methods. The intervention will be implemented in three phases, and for each phase, we will seek ethical clearance and approval prior to data collection. At the moment, we are seeking ethical clearance for the first phase where we intend to conduct focus group discussions to obtain women's perceptions and suggestions about the intervention to inform the development of the intervention.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Amon Agaba
ID:
The quality and safety standards of herbal medicine production and vending in greater Mbarara District
REFNo: HS720ES

General Objective:
To document the adherence and practice required to maintain the quality and safety of herbal medicine production and vending in Mbarara District.

Specific Objectives:
I.To document the adherence to standard herbal medicine production guidelines by herbal medicine producers and vendors in Mbarara District
II.To explore the enablers and barriers to adherence to the recommended guidelines that govern the production and vending of herbal medicine in Mbarara District.

 Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Josephine Nabukenya Kwagala
ID:
ASSESSING THE POTENTIAL FOR TRANSFORMING HEALTH IN UGANDA THROUGH AN ELECTRONIC HEALTH DATA SHARING PLATFORM AND DATA SCIENCE
REFNo: HS1005ES

General Objective:
To explore the readiness malaria and HIV as potential demonstrator conditions for an EHR data capturing and processing system infrastructure and analytical methods that could support Uganda’s Ministry of Health and related health institutions to provide responsive care and interventions based on real-time surveillance.

Specific Objectives:
Objective 1: To (a) develop a complete understanding of the routine care data currently captured and all surrounding dynamics including timing of capture by whom and how and what the current state of onward use is and (b) determine how these will influence data capture with electronic point of care capture systems.

Objective 2: To determine what technical, ethical/governance and workforce infrastructure are required for a timely model data capture system that addresses medical, public health and research needs of stakeholders.

Objective 3: In order to determine readiness, we will (a) model the cost of each proposal/ model system and determine on-going cost and potential cost recovery, including the cost of all other components (i.e., Buy-in, Timeliness, Capability) and determine what would be required to eliminate key barriers; and (b) map our data to EHR data capture and processing readiness frameworks.


Objective 4: To provide examples of cost effectiveness by determining how much additional malaria and/or HIV control would be required to offset the cost of the system over various time periods.

Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
 National Study on the impact of contentious issues and masculinities on the realization of Sexual and Reproductive Health and Rights in Uganda
REFNo: SS537ES

General Objective: To generate evidence for SRHR advocacy and programming in Uganda
Specific objectives are;
1. To document the journey of the Sexual and Reproductive Health and Rights movements in Uganda
2. To explore the relationship between masculinities and sexual reproductive health and rights
3. To examine the influence of contentious issues like abortion, and LGBTQI on the realization of SRHR

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
 Evaluation of the Clinical Performance of a Plastic Capillary Tube with the Determine HIV-1/2, Determine HIV Early Detect and Determine HBsAg 2 Rapid Tests
REFNo: HS895ES

The primary objective of this study is to evaluate the performance of a new plastic capillary tube for the transfer of a capillary finger-stick blood sample to 3 rapid test platforms; the Determine HIV-1/2 test platform, the Determine HIV Early Detect test platform and the Determine HBsAg 2 platform. The HIV and HBsAg results obtained using the new plastic capillary tubes to transfer capillary whole blood to the test devices will be evaluated against the HIV and HBsAg results obtained using a micropipette to transfer a whole blood venous sample from the EDTA Vacutainer tube to the same testing platforms, with discrepant result resolution where required. The new plastic capillary tubes have been verified in an internal performance study at the Abbott laboratories.
 UK 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Edward  Bitarakwate
ID:
Evaluation of Patient and Program Outcomes Achieved through EGPAF-supported Integrated HIV and TB Prevention, Care, and Treatment Programs in Uganda
REFNo: HS930ES

Primary Objectives:
1.To determine patient and program outcomes for children, adolescents and adults receiving HIV and TB services in EGPAF supported facilities and through EGPAF supported programs.

Secondary Objectives:
1. To determine outcomes of HIV testing strategies targeted at identifying HIV positive children, adolescents, and adults in facilities and the community including the number and proportion identified as HIV-positive, linked to HIV services, and initiated on ART in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome along the testing to treatment cascade.

2. To determine clinical and laboratory outcomes among HIV-positive children, adolescents and adults enrolled in HIV services such as morbidity (including coinfections), mortality, ART regimen, ART adherence, retention in care, viral suppression, and disease progression in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome, including baseline clinical characteristics before initiating ART.

3. To determine the outcomes of HIV prevention activities (including PMTCT) among pregnant women, discordant couples, adolescents and other key and priority populations in facilities and the community including the number accessing prevention services by risk category, retention in services, and seroconversion rates.
a. To determine individual, population, and program characteristics/factors associated with the HIV prevention outcomes.

4. To determine clinical and laboratory outcomes among children, adolescents and adults accessing TB screening/diagnosis, prevention, and treatment services such as HIV/TB coinfection rates, initiation and adherence to IPT, initiation and adherence to TB treatment, retention in care, treatment outcomes for drug resistant TB, mortality.
a. To determine individual, population, and program characteristics/factors associated with each outcome.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
 “Assessment of circulating proteins in Ugandan tuberculosis household contacts for latent TB infection biomarker development: Version 1.0 dated 14 Sept 2020”
REFNo: HS958ES

Refine our protein signature to function in HIV-positive persons, incorporating cytokine and chemokine markers as needed.
2. Refine our protein signature to identify Mtb infection that has developed within a 6-month timeframe.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Esther Nanfuka Kalule
ID:
Livelihood Resilience During the COVID-19 Lockdown: Practices of Informal Sector Populations in the Urban and Peri-urban Settings of Kampala and Wakiso Districts
REFNo: SS619ES

The study will specifically:
• Examine the current livelihood practices and resources among urban informal sector workers in the context of restricted mobility and social distancing
• Examine the opportunities and challenges for vulnerable urban informal sector workers to negotiate and reconfigure livelihood sources including social networks and social capital for support in a lockdown situation
• Assess the most valued livelihood sources (assets, capabilities, activities) under the lockdown and preferred areas of allocating available resources among different categories of the informal urban population
• Examine the potential and perceived risks (including public health) of the livelihood activities undertaken during the COVID-19 lockdown

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
ARTHUR  SEKIZIYIVU BRIAN
ID:
END-LINE EVALUATION OF AN HIV PREVENTION PROJECT IMPLEMENTED BY UGANDA PEOPLE’S DEFENSE FORCES AND PACE
REFNo: HS989ES

I. Measure changes in the knowledge, attitudes and practices among the military and AGYW to adopt and sustain positive behavior change.
II. Identify challenges, innovations, lessons, and success stories across the interventions
III. Identify the opportunities to integrate prevention interventions within (into) an HIV care program

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Hannington Odongo Jawoko
ID: UNCST-2024-R002457
 The Relationship between Social Governance and Smallholder Farmer Socio-Economic Resilience: Moderating Effects of Pluralistic Agriculture Extension Service Provision in Northern Uganda
REFNo: A78ES

To investigate the moderating effects of perceptions of the quality of pluralistic agricultural extension services provision on social governance exhibited in participatory local government planning and budgeting process.

To examine the influence of social governance exhibited in participatory local government planning and budgeting process on the values and needs of smallholder farmers in northern Uganda.

To assess the impacts of perceptions of the quality of pluralistic agricultural extension services provision on socio-economic resilience of smallholder farmers in northern Uganda.

To examine the impacts of social governance exhibited in participatory local government planning and budgeting process on smallholder farmer’s socio-economic resilience in northern Uganda.

 Uganda 2020-11-09 2023-11-09 Agricultural Sciences Degree Award
Anthony Mugeere Buyinza
ID:
THE IMPRINT OF EDUCATION: A LONGITUDINAL COHORT STUDY OF AFRICAN ALUMNI OF THE MASTERCARD FOUNDATION SCHOLARS PROGRAM
REFNo: SS543ES

(i) To provide evidence at multiple levels on the individual, structural, contextual and programmatic factors that mediate Scholars’ outcomes especially with regards to “return”, “giving back”, “transformative and ethical leadership”

(ii) To assess the imprint of education on the lives of individuals, communities and societies in contexts such as those on the African continent in which Mastercard Foundation (MF) provides scholarships.

(iii) To examine the links between socio-economic inclusion, education and development.

(iv) To understand what works and why, as well as what might be done to improve the MSP and maximise the impact of Scholars as agents in the social and economic transformation of the African continent (by considering their social networks, support and training received, the way in which institutions contributed to their success, and their employment and employment creation trajectories).
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Non-degree Award
Augustine Ssevviri Kaddu Musisi
ID:
Using the Health Belief model to increase the level of knowledge, attitudes and practices of COVID-19 prevention measures in Wakiso district, Uganda
REFNo: HS883ES

1.0 Main Objective
To understand the level of adherence towards the COVID-19 guidelines and assess the knowledge and attitudes regarding COVID 19 in order design a behavioral change intervention that enhances knowledge and promotes compliance to the prescribed COVID-19 practices at the grassroots level in Wakiso district, Uganda
1.1 Specific Objectives
• To determine the level of knowledge about the prevention of COVID-19 among the people in Wakiso district
• To understand community attitudes towards the prevention of COVID-19 in Wakiso district
• To determine the level of adherence to COVID-19 prevention guidelines among community members in Wakiso District
• To design a behavioral change communication intervention for improving people’s knowledge, attitudes and level of adherence towards COVID-19 guidelines

Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
willy waninga
ID:
The use of ICT in the teaching of integrated science in Primary Teachers' Colleges in Uganda: A case of Four Primary Teachers' Colleges
REFNo: SS594ES

1. To find out ICT tools used by science tutors in teaching integrated science education
2. To find out how science tutors use technological content knowledge in planing integrated science education lessons.
3. To find out how integrated science education tutors integrate technological content knowledge in the pedagogy of science education.
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Degree Award
Herbert Kayiga Kayiga
ID:
IMPACT OF COVID-19 PANDEMIC ON MATERNAL AND NEWBORN HEALTHCARE SERVICE DELIVERY IN PRIVATE AND PUBLIC FACILITIES IN UGANDA
REFNo: HS924ES

STUDY OBJECTIVE:
To determine the impact of COVID-9 pandemic on the provision of maternal and newborn services in Kampala, Uganda

SPECIFIC OBJECTIVES:
1. To determine the quality of maternal and newborn service provision in Kampala, Uganda before the COVID-19 pandemic.
2. To determine the quality of maternal and newborn service provision in Kampala, Uganda during the COVID-19 pandemic.
3. To seek understanding of the experiences of the health workers as they provide maternal and newborn services in Kampala, Uganda.
4. To seek understanding of the pregnant and breastfeeding mothers’ experience as they seek maternal and newborn services in Kampala, Uganda.

 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Matthew  Cotten Louis
ID:
Local sequencing of SARS-CoV-2 from Uganda COVID-19 cases
REFNo: HS936ES

To document the transmission dynamics of COVID-19 in Uganda using full viral genome sequencing
 USA 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Title: Analysis of A Tool To Assess Psycho Social Spiritual Healing: Cognitive Interviewing
REFNo: HS957ES

1. To determine the face and content validity of the NIH-HEALS

2. To determine the comprehensiveness, comprehensibility and acceptability of the NIH HEALS in Uganda
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
 Leveraging the HIV platform for hypertension control in Uganda (INTEGRATED HIV/HTN)
REFNo: HS979ES

1 To determine the effectiveness of an integrated HIV/HTN care model on HTN and dual
HIV/HTN control among adult patients in HIV clinics.
2 To assess the barriers and facilitators of the integrated HIV/HTN care model for HIV
patients at different levels.
3 To determine the cost, cost-effectiveness and incremental gain costs of the integrated
HIV/Hypertension care model approach
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Grace Edwards
ID:
An exploration of the need for Nursing and Midwifery Leadership Capacity Building in Uganda
REFNo: HS562ES

The study is aimed at exploring the leadership training needs for nurses and midwives in Uganda, in order to develop recommendations for developing nursing and midwifery leaders in Uganda and draft a leadership training programme.
 UK 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
 INCIDENCE & PREDICTORS OF ABNORMAL RENAL FUNCTION THREE MONTHS AFTER DELIVERY AMONG PREECLAMPSIA SURVIVORS AT MULAGO HOSPITAL
REFNo: HS341ES

To determine the incidence and predictors of abnormal renal function three months after delivery among preeclampsia survivors at Mulago Hospital.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Kintu  Mugagga
ID:
Comparative Assessment of Anatomical and Neuro-Cognitive Characteristics Between Vaginally And Caesarean Section Delivered Children of 1-2 years Age At Mbarara Regional Referral Hospital, South-Western Uganda
REFNo: HS397ES

i) To describe the differences in the head-size and body height between VD and CSD children at 1-2 years of age born at Mbarara Regional Referral Hospital.


ii)To describe the differences in neurocognitive characteristics between VD and CSD children at 1-2 years of age born atMbarara Regional Referral Hospital.


iii)To describe the perinatal and socio-demographic characteristics of the mothers to the VD and CSD childrenof 1-2 years of age delivered at Mbarara Regional Referral Hospital.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Owning our future through community engagement: enhancing uptake of COVID-19 prevention and mitigation measures”
REFNo: HS858ES

Specific Objectives
1. Ascertain the:
a) Prevailing attitudes and perceptions towards COVID-19 mitigation measures and community response and adaptation (behaviours, practices) to the “new social norms” imposed by the emergency response;
b) Short-term socioeconomic impact and community coping mechanisms
2. Develop and implement a community engagement intervention for enhancing uptake of the recommended COVID-19 public health and social mitigation measures.
3. Evaluate the effects of the intervention developed in 2 above on acceptance and uptake of the COVID-19 prevention and mitigation measures.

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Martha Nabadda
ID:
A qualitative case study exploring health workers’ perspectives on facilitators and barriers to comprehensive management of sickle cell disease in young adults aged 18 – 25 years accessing primary care in Uganda.
REFNo: HS616ES

i. To investigate the facilitators and barriers to comprehensive management of sickle cell disease, using a focused group discussion and ten semi-structured, in-depth interviews with healthcare workers at three sickle cell clinics in Uganda.

ii. To explore the care and support needs specific to young adults with sickle cell disease accessing the health system at the point of primary care.

iii. To make care and policy recommendations for the Ministry of Health to improve guidelines for the provision of sickle cell disease care in public health facilities in Uganda.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Abner Tagoola
ID: UNCST-2021-R013446
 Enhancing maternal participation in neonatal hospital care using an adapted Family Integrated Care (FICare) program
REFNo: HS632ES

The purpose of this study is to adapt and test a model of enhanced maternal participation (FICare) in a neonatal hospital unit in Uganda. This is with the goal of increasing the level of patient monitoring and ultimately improving the quality of care that sick and small newborns receive in the hospital. Specifically, the study is
1. To determine the acceptability of implementing an adapted FICare model, specifically maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase I)
2. To test the feasibility of implementing maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase II)

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
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