Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Margaret Bryer
ID: UNCST-2024-R016311
 Social nutrition in guenons in Uganda
REFNo: NS895ES

I will investigate the effects of conspecific sociality on nutritional intake and nutrient balance in two forest guenon species in Uganda. Though we will investigate the nutrition of both sexes, we will start by examining adult female guenon social nutrition. Female guenons may face a tradeoff between (1) competition with conspecifics, potentially in the context of shallow dominance hierarchies, and with other monkey species and (2) their own nutritional goals. I will examine conspecific social behavior and nutrition at Kanyawara site, Kibale National Park, where I will continue my redtail nutrition work (Bryer 2020) examining nutrient intake and balance of female redtails in the context of conspecific and heterospecific feeding competition. I will also examine diet, then nutrition, and social behavior of females in one L’Hoest’s monkey group.
USA 2025-03-10 16:19:38 2028-03-10 Natural Sciences Non-Clinical Trial Non-degree Award
KAJJABWANGU RONALD
ID: UNCST-2024-R003479
 UTILIZATION OF PRECONCEPTION CARE AMONG WOMEN OF REPRODUCTIVE AGE ATTENDING ANTE-NATAL CLINIC SERVICES AT ANYEKE HEALTH CENTER IV, OYAM DISTRICT, NORTHERN UGANDA
REFNo: HS5626ES

To determine the health system factors associated with utilization of preconception services among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District.,To determine the socio Demographic factors associated with utilization of preconception services among women attending ANC services at Anyeke Health Center IV of Oyam District ,To determine the level of knowledge on PCC among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District ,To determine the level of uptake of preconception care services among women age attending ANC services at Anyeke Health Center IV of Oyam District ,To assess the level of Utilization of preconception care among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District ,
 Uganda 2025-03-10 16:18:19 2028-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
 Feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting.
REFNo: HS2676ES

Our aim is to explore the feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting. The specific objectives will be:
1. To explore the feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
2. To explore the safety of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
3. To understand the and acceptability of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
4. To generate a list of the most robust clinical outcome measures for a future effectiveness evaluation

 Uganda 2025-03-10 16:14:38 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Femke Bannink Mbazzi Bannink
ID: UNCST-2023-R008308
 Disability Inclusive Youth (DIY) research: an innovative and co-creative study to improve inclusion of children and youth with disabilities in health research in East Africa
REFNo: SS3665ES

The aim of this study is to explore barriers and facilitators to the inclusion of children and youth with disabilities in health research, co-create solutions to make health research in East Africa disability disability-inclusive, and create a disability knowledge and research centre to inform and support inclusive health research in the region. In this study, we will use the African Youth’s Charter’s definitions of children (0-18 years) and youth (15-35 years). The study has 3 core objectives: 1) co-creative innovative participatory disability health research with youth with disabilities to understand the barriers and facilitators of inclusion of children and youth with disabilities in health research, 2) co-design solutions to make health research inclusive of children and youth with disabilities, 3) capacity building of research teams, co-production and sharing of knowledge with youth with disabilities
Netherlands 2025-03-10 16:13:24 2028-03-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Betty Akwongo
ID: UNCST-2021-R003759
 BIOACTIVITY AND SAFETY OF MEDICINAL PLANTS USED IN THE MANAGEMENT OF CANDIDIASIS IN PADER DISTRICT, NORTHERN UGANDA
REFNo: NS929ES

Main objective: To document and investigate the efficacy and safety of medicinal plants used for treatment of candidiasis in Pader district.

Specific objectives:
1.Document medicinal plant species used to treat candidiasis in Pader District
2.Determine the antifungal activity of priority plants against Candida albicans, Candida glabrata and Candida tropicalis.
3.Evaluate the acute and subacute toxicity of the most active plant species used for treatment of candidiasis.

 Uganda 2025-03-10 16:12:24 2028-03-10 Natural Sciences Non-Clinical Trial Degree Award
Betty Akwongo
ID: UNCST-2021-R003759
 Inventory of Medicinal and Nutraceutical Plants of West Nile Region for Establishment of Botanical Garden in Muni University, Northern Uganda
REFNo: NS931ES

1. To carry out ethno-botanical survey of medicinal and nutraceutical plants used for management/ treatment of various diseases in West Nile region, Northern Uganda.
2. To document usage of medicinal and nutraceutical plants of West Nile region so as to conserve and preserve the traditional indigenous knowledge
3. To find out the ecology of the medicinal and nutraceutical plants of West Nile region to guide future creation of botanical garden

 Uganda 2025-03-10 13:46:41 2028-03-10 Natural Sciences Non-Clinical Trial Non-degree Award
Okello Ronald
ID: UNCST-2024-R002778
 Board of Governors Outlook and the Educational Performance of Catholic-Founded Schools in Uganda
REFNo: SS3659ES

i) To establish the influence of board independence on the educational performance of Catholic founded Grant Aided Secondary Schools in Uganda.
ii) To determine the influence of board composition on the educational performance of Catholic founded Grant Aided Secondary Schools in Uganda.
iii) To examine the head teacher’s role duality and its influence on the educational performance of Catholic founded Government Aided Secondary Schools in Uganda.

 Uganda 2025-03-10 13:44:32 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Kishaija Noel
ID: UNCST-2024-R004309
 Assessing the impact of climate change on farming systems and livelihoods of smallholder coffee farmers in Southwestern Uganda
REFNo: A551ES

i. To document production systems, livelihood sources, and climate change adaptation practices among smallholder coffee farmers in Southwestern Uganda
ii. To determine how climate change has changed coffee farming systems among smallholder coffee farmers in Southwestern Uganda
iii. To determine the relationship between livelihood components and climate change adaptation strategies among smallholder coffee farmers in Southwestern Uganda
iv. To determine the relationship between gender and climate change adaptation strategies among smallholder coffee farmers in Southwestern Uganda
v. To recommend policy interventions that will enhance the sustainability of smallholder coffee production

 Uganda 2025-03-10 13:29:02 2028-03-10 Agricultural Sciences Non-Clinical Trial Degree Award
Josephine Akellot
ID: UNCST-2024-R016329
 Applying findings from prior mental health training and supervision research in rural Ugandan settings: a transdisciplinary research proposal
REFNo: SS3626ES

1. To explore retrospective and future-looking stakeholders’ perspectives on the scope and complexity of task-shifting training and supervision in mental health care
2. To explore retrospective and future-looking policy voice-over the strategy to follow before, during and after task-shifting training and supervision in mental health care

Uganda 2025-03-10 13:24:40 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Elizabeth Ekirapa
ID: UNCST-2020-R014390
 Opt-AMR: Optimizing Antibiotic Usage to Mitigate AMR
REFNo: HS5547ES

Aim: To develop a metric and evidence use process for improving the management of childhood febrile illness in community settings.

Objectives
1) Investigate associations of QoC in a sample of healthcare facilities (HCFs) with AMR to key antibiotics used for febrile illnesses in children.
2) Assess the risk of AMR development through analysis of genomic traits from samples collected in study sites; determine future risk of resistance development.
3) Use mixed methods to investigate community level health system drivers of ABU and AMR at the district level with particular focus on febrile illnesses.
4) Develop a rapid and recurrent surveillance system of ABU and AMR prevalence and of community voices in districts for evidence-based improvement of health system strategies and policies.
 Uganda 2025-03-10 13:18:54 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jamil Wesigomwe Mohammed
ID: UNCST-2024-R015957
 Understanding Conflicts in the Management of Construction of Public Water Works Projects in Uganda
REFNo: SS3725ES

vi. To develop a robust model for efficient and effective conflict management in construction of public water works projects in Uganda,v. To assess the effectiveness of the existing conflict management approaches in the management of construction of public water works projects in Uganda.,iv. To examine the consequences of administrative conflict in the management of construction of public water works projects in Uganda.,iii. To assess the effect of technical conflict in the management of construction of public water works projects in Uganda.,ii. To evaluate the influence of contractual conflict in the management of construction of public water works projects in Uganda.,i. To determine the effect of behavioural conflict in the management of construction of public water works projects in Uganda.,The main objective is to investigate the sources of conflicts in the management of construction of public water works projects in Uganda and devise effective conflict management strategies. ,
 Uganda 2025-03-10 13:13:56 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 Reducing violence against children and intimate partner violence in Uganda: Feasibility Study of Digital Delivery of the Parenting for Respectability Programme
REFNo: HS5488ES

Overall research objective
The overarching objective of the study is to test the readiness, feasibility, and initial effectiveness of the PfR-App in reducing VAC, IPV, and optimising male engagement in order to lay grounds for a Randomised Controlled Trial (RCT) and eventual wider scale-up of the programme.
The specific objectives are to:
1. Assess users’ and facilitators’ perspectives and experiences, acceptability and satisfaction with the PfR-App functionality across contexts and sub-populations.
2. Use the in-app data collection tool to measure evidence of the initial effectiveness of the app by evaluating at the immediate post-test the effect of the digital intervention on knowledge, attitude and practices in parenting.
3. Compare different population characteristics and different delivery options on parents’ engagement with the App and evidence of initial effectiveness, acceptability, attrition, relevance, engagement, usability, and satisfaction.
4. Test the impact of the design features and content of the PfR-App on initial parental engagement and retention in order to achieve the highest possible fidelity/participation rates in the one month after enrolment and use it to improve the App experience for target users.
5. Test the impact of various factors including the timing, frequency, length and order of sessions, push notifications and in-App survey questions on engagement and response rates in order to implement the most effective strategies to achieve the highest possible engagement and retention rates, including optimising male engagement.


Uganda 2025-03-10 13:12:40 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KEVIN ABER
ID: UNCST-2024-R002518
 Microservice Framework for Research Data Management: A Case of Interdisciplinary Research Project-UPCHAIN
REFNo: SIR465ES

To validate MF-RDM using the RDMS,To implement the Research Data Management System (RDMS) based on the developed MF-RDM framework.,To design a Microservice Framework for Research Data Management (MF-RDM).,To determine data requirements for RDM based on the work package in the UPCHAIN interdisciplinary research project.,To develop a scalable Microservice Framework for Research Data Management (MF-RDM).,
 Uganda 2025-03-10 13:02:30 2028-03-10 Engineering and Technology Non-Clinical Trial Degree Award
Robert Odendi Gideon
ID: UNCST-2024-R002130
 ALCOHOL USE, COGNITIVE FUNCTIONS, AND DEMENTIA SUSCEPTIBILITY AMONG ADOLESCENTS IN IBANDA AND LIRA DISTRICTS, UGANDA
REFNo: HS5517ES

4. To explore the proposed approaches to address adolescent alcohol use in Uganda.,3. To explore the perceptions regarding alcohol use among adolescents in Uganda. ,2. To assess the factors associated with cognitive impairment and risky behavioural patterns among adolescents with alcohol use in selected regions of Uganda,1. To determine the prevalence of cognitive impairment and risky behavioural patterns among adolescents who use alcohol in selected regions of Uganda.,To determine the prevalences and factors associated with cognitive impairment and risky behavioral patterns among adolescents who use alcohol, and explore the perceptions of alcohol use among adolescents, and proposed interventions to address adolescent alcohol use in Uganda,
 Uganda 2025-03-10 12:54:08 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Nkangi
ID: UNCST-2021-R012153
 ASSESSMENT OF VACCINE RESPONSES IN 3D TONSIL CULTURES
REFNo: HS5501ES

1. Assess humoral and cellular responses to vaccines and evaluate the vaccine induced metabolic profiles.
2. Modulate vaccine responsiveness using metabolic and immunologic modulatory compounds.
 Uganda 2025-03-10 12:47:51 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Defining the Risk Factor Cascade in Rheumatic Heart Disease
REFNo: HS5503ES

Aim 1: Identify modifiable risk factors for developing RHD using prospective population case-control methodologies. Aim 2: Determine the independent and joint contributions of multi-level risk factors for RHD among children and adults in Uganda. Aim 3: Establish a biobank of RHD patients' tissue samples for future RHD research studies.
Uganda 2025-03-10 12:29:08 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Schola  Matovu Nakachwa
ID: UNCST-2022-R011040
 Development and Testing of BAJJAJJA: An Intervention to Promote Economic Empowerment and Health of Grandmothers who Provide Primary Care for Grandchildren in Uganda
REFNo: SS3611ES

Main Objective
The study’s objective is to refine and test the feasibility and acceptability of my innovative intervention, BAJJAJJA: Building A Joint Action for JaJJAs which couples an income- generating activity (IGA) with nurse-facilitated group health coaching. This objective is informed by the NIH Stage Model of behavioral intervention development.

Specific Objectives
Aim 1: To refine and adapt the BAJJAJJA intervention through a collaborative and iterative feedback process with a diverse community group of 18 members. In a series of sessions, I will iteratively engage diverse community groups (nurses, local officials, IGA experts, and GMCs) and use cognitive interviewing to gain feedback on the appropriateness of study measures, content, delivery, and intervention format.
Aim 2: To test the feasibility, acceptability, and preliminary efficacy of the BAJJAJJA intervention in improving economic and health outcomes among 24 Ugandan GMCs. Over a 12-month period and at three time points of assessment, I will use a mixed methodology with a quasi-experimental design to collect data that will be examined to assess the feasibility, acceptability, and preliminary efficacy of the intervention on participants’ household income and health outcomes.
Aim 3: To explore the barriers and facilitators to (3a) maintenance of the BAJJAJJA individual intervention benefits (e.g., physical activity level and frequency) and (3b) sustainability of the IGA activities (e.g., grandmothers’ accessing external supports such as community resources) at 6 months post-intervention. Following a mixed methods approach, the 24 GMCs from Aim 2 will be interviewed to further evaluate the long-term maintenance and sustainability of the intervention. Health assessments, interviews, and IGA site visits will be used to explore the intervention outcomes and benefits at 6 months post-intervention.

USA 2025-03-10 12:23:29 2028-03-10 Social Science and Humanities Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Randomized trial to evaluate the efficacy and safety of select therapeutic agents in the treatment of Ebola Disease (TOKOMEZA - Ebola Disease Therapeutics)
REFNo: HS5686ES

This is an open-label, adaptive, randomised platform clinical trial to evaluate the impact of 278 potential treatments on mortality in patients with Ebola Disease
 Uganda 2025-03-07 18:39:19 2028-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Shillah  Kwikiiriza
ID: UNCST-2021-R012682
 Entrepreneurship among rural youth in the Kamuli district, Uganda,
REFNo: A575ES

I. Identify the specific entrepreneurship opportunities available for youth in the Kamuli district
II. Inform YEP of the potential entrepreneurship opportunities for improved and sustained youth livelihoods in Kamuli district.
 Uganda 2025-03-07 18:36:02 2028-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Andrew Kanyike Marvin
ID: UNCST-2020-R014554
 Exploring Fund-Pooling Peer-led Patient Support Groups among Hypertension and Diabetes Mellitus Patients in Public Health Facilities in Uganda.
REFNo: HS5668ES

1. To map out fund-pooling peer-led patient support groups for hypertension and diabetes patients at public health facilities in Uganda.

2. To explore the operational mechanisms faced by fund-pooling peer-led patient support groups for hypertension and diabetes patients at public health facilities in Uganda.

3. To explore the barriers and facilitators to hypertension and diabetes patient involvement in fund-pooling peer-led patient support groups at public health facilities in Uganda.
 Uganda 2025-03-07 18:34:54 2028-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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