Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
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IDENTIFICATION OF VIRULENCE FACTORS, TRANSMISSION PATTERNS AND ANTIBIOTIC RESISTANCE MECHANISMS OF EAST AFRICAN Vibrio cholerae ISOLATES BY WHOLE GENOME SEQUENCING
REFNo: HS338ES
Aim: To obtain whole genome sequences (WGS) of Vibrio cholera O1 isolated in various parts of Uganda from 2014 to 2018 and use the data to determine the evolution, spread, antimicrobial resistance mechanisms and pathogenesis of the isolates
Specific objectives:
1. Determine patterns of spread of V.cholerae O1 in Uganda and within the East African region using WGS
2.Infer relatedness and evolution of strains of V.cholerae O1 isolated in Uganda and the East African region from WGS data
3.Identify any uniqueness in virulence genes or their expression among strains of V.cholerae isolated in Uganda and the East African region from WGS data
4.Identify genes of antimicrobial resistance and infer prevailing mechanisms of antimicrobial resistance among V. cholerae O1 isolated in Uganda
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Uganda |
2019-05-14 |
2022-05-14 |
Medical and Health Sciences |
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Non-degree Award |
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Catriona Waitt John
ID: UNCST-2019-R001068
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INVESTIGATION OF THE PHARMACOKINETICS OF ATAZANAVIR IN PREGNANT WOMEN, INDIVIDUALS AT EXTREMES OF BMI, CHILDREN AND ADOLESCENTS. AN OBSERVATIONAL STUDY NESTED WITHIN THE VIRTUAL CONSORTIUM
REFNo: HS351ES
Primary Objectives
1. To describe the pharmacokinetic parameters of ATV currently used in the clinical care of HIV-infected pregnant and postpartum women, children and adolescents, and individuals with obesity or malnutrition.
2. To compare these parameters to those observed in non-pregnant HIV-infected adults on second-line ART who enter a dose escalation study of ATV/r + RIF as WP2 of the VirTUAL programme
Secondary Objectives
1. To use nonlinear mixed-effects modelling to describe sources of variability on the pharmacokinetics of ATV
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UK |
2019-05-14 |
2022-05-14 |
Medical and Health Sciences |
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Non-degree Award |
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PALLAVI PRABHAKAR
ID:
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Reproductive and maternal health care provision for refugees and host populations in Northern Uganda
REFNo: SS296ES
This study aims to undertake:
1.A policy analysis to examine access and health financing arrangements for Sexual
, Reproductive and Maternal Healthcare (SRMH) and the delivery of these services for refugees and host populations in Uganda, in the context of transition from an acute emergency to a development response model.
2.An impact , process and economic evaluation of the BRAC ELA programme which aims to train the adolescent girls on issues related to health, nutrition, financial literacy, and life skills.
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India |
2019-05-14 |
2022-05-14 |
Social Science and Humanities |
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Non-degree Award |
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Daniel Atwine Warren
ID:
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Community Intervention for Tuberculosis Active Contact Tracing and Preventive Therapy - A Cluster Randomized Study (CONTACT)
REFNo: HS329ES
To compare the proportion of household child TB contacts eligible for PT (<5 years and HIV-infected children 5-14 years without active TB) who initiate and complete PT using facility-based and decentralized community-based models of care for contact screening and management.
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Uganda |
2019-05-07 |
2022-05-07 |
Medical and Health Sciences |
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Non-degree Award |
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Shallon Atuhaire
ID:
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Self-fulfilling Prophecies and Self-efficacy: Association with Community Reintegration and Rehabilitation of Obstetric Fistula Patients in Kitovu Hospital, Uganda
REFNo: HS361ES
i. To identify self-fulfilling prophecies among repaired and unrepaired obstetric fistula patients in Kitovu Mission Hospital.
ii. To assess the highest level of self-efficacy among repaired and unrepaired obstetric fistula patients in Kitovu Mission Hospital.
iii. To determine the role played by self-fulfilling prophecies in community reintegration and rehabilitation of obstetric fistula in Kitovu Mission Hospital.
iv. To measure the association between obstetric fistula patients’ levels of self-efficacy and their rehabilitation in Kitovu Mission Hospital.
v. To explore the extent to which obstetric fistula patients of different fistula repair statuses are involved in rehabilitation in Kitovu Mission Hospital.
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Uganda |
2019-05-07 |
2022-05-07 |
Medical and Health Sciences |
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Degree Award |
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Musa Kayondo
ID:
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PELVIC ORGAN PROLAPSE IN SOUTHWESTERN UGANDA: PATTERNS, IMPACT ON QUALITY OF LIFE, SURGICAL OUTCOMES AND THE PREDICTING FACTORS, OF PATIENTS ATTENDING MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS368ES
1. To determine the patterns of POP in the Gynecology department of MRRH.
2. To establish the quality of life (physical, social, emotional and sexual function) before and after surgery among women with POP at MRRH.
3. To determine the outcomes of surgical treatment and related prognostic factors of POP at MRRH.
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Uganda |
2019-05-07 |
2022-05-07 |
Medical and Health Sciences |
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Degree Award |
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Katia Peterson
ID:
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A quasi-experimental study of Interpersonal Group Therapy (IPT) treatment attribution on decreasing depression severity among depressed women in Iganga District, Makuutu Sub County and Mukono District, Kimenyedde Sub Counties
REFNo: SS297ES
General objective
To establish a baseline prevalence of depression and determine the period and treatment effects of depression severity between depressed women in Iganga (Makuutu Sub County) and Mukono District (Kimenyedde Sub Counties).
Specific objectives
1. Determine the prevalence of depression in Makuutu Sub County (Iganga) and Kimenyedde Sub Counties (Mukono).
2. Determine the change in depression severity, as measured by the PHQ-9, within control subjects at six months and one year follow up.
3. Determine the change in depression severity, as measured by the PHQ-9, between control and treatment subjects at six months and one-year follow up.
4. Determine the change in well-being as measured by the “Well-being Indicator Survey” within control subjects and between control and treatment subjects at six months and one year follow up.
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USA |
2019-05-07 |
2022-05-07 |
Social Science and Humanities |
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Non-degree Award |
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NICHOLAS BARI NDAHURA BARI
ID:
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EFFECTIVENESS OF NUTRITION EDUCATION ON GLYCAEMIC CONTROL IN PEDIATRIC TYPE 1 DIABETES MELLITUS PATIENTS IN UGANDA
REFNo: HS186ES
1. To assess the level of knowledge of nutrition management of T1DM among caregivers of T1D children (3-12 years) at selected T1DM clinics in Uganda.
2. To determine the dietary intake and adequacy of T1D children (3-12 years) at selected T1DM clinics in Uganda.
3. To develop a nutrition education training module for caregivers and T1D children (3-12 years) at selected T1DM clinics in Uganda.
4. To determine the effectiveness of nutrition education on HbAlc levels, knowledge of nutrition management of T1DM and dietary practices among caregivers and T1D children (3-12 years) at selected T1DM clinics in Uganda.
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Uganda |
2019-04-30 |
2022-04-30 |
Medical and Health Sciences |
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Degree Award |
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Isaac Kimbowa
ID:
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ANTIMICROBIAL STEWARDSHIP PRACTICES AND QUALITY OF ANTIBACTERIAL USE IN CHILDREN UNDER-FIVE IN SELECTED HEALTH FACILITIES IN UGANDA
REFNo: HS339ES
1. To determine the structure and functional roles of MTCs in optimizing antibacterial use in management of childhood infections in under-five children in selected RRHs and PNFP health facilities in Uganda (sub-study I).
2. To determine stewardship practices guiding optimizing antibacterial use in management of infections in under five children in selected Health facilities in Uganda (sub-study II)
3. To determine extent of off-label and unlicensed use of antibacterial among children -five in paediatrics wards of selected RRHs and PNFPs in Uganda (Study III)
4. To determine the extent of antibacterial exposure to neonates during perinatal period among women delivering in selected regional referral hospitals in Uganda (Study IV).
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Uganda |
2019-04-24 |
2022-04-24 |
Medical and Health Sciences |
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Degree Award |
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Julia Downing
ID:
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Children’s, Adults and Health Professionals Understanding Illness, Death and Dying in Uganda
REFNo: HS276ES
The study aims to gain an understanding of children, adults and health professionals understanding of illness, death and dying in order to inform the provision of palliative care services in Uganda. The objectives of the study are to understand the following questions:
I. What are Ugandan adults understanding of illness, death and dying?
II. What are Ugandan children’s understanding of illness, death and dying?
III. What is the understanding of Ugandan health professionals with regards to illness, death and dying?
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UK |
2019-04-16 |
2022-04-16 |
Medical and Health Sciences |
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Non-degree Award |
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