Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Lauren Hookham
ID: UNCST-2024-R016386
Characterising colonisation and transmission of Multi-Drug-Resistant Gram-negative organisms in maternal care in Uganda - GRam negative Resistance In Pregnancy (GRIP)
REFNo: HS8128ES

Overall aim: To characterise colonisation and transmission of multi-drug-resistant Gram-negative bacteria (MDR-GNB) within the maternity unit at Kawempe National Referral Hospital (KNRH), Kampala, Uganda, and evaluate interventions to reduce environmental contamination and improve infection prevention and control (IPC) practices.

Work Package 2: Characterise MDR-GNB colonisation in women undergoing elective and emergency caesarean section, their newborns, and the maternity hospital environment at KNRH; identify individual, clinical and environmental risk factors for maternal colonisation; and examine genetic similarity between environmental and patient-derived MDR-GNB strains.

Work Package 3: Explore how systemic and environmental context, resource availability, infrastructure, supervision, attitudes, perceptions, roles, responsibilities, training needs, communication and feedback influence IPC and cleaning practices among healthcare workers, cleaning staff and supervisors.

Work Package 4: Use Intervention Mapping to conduct a needs assessment and identify behavioural and environmental determinants; implement structured training for cleaning staff using the WHO Environmental Cleaning Toolkit; assess changes in the burden of Gram-negative and MDR Gram-negative bacteria in the maternity/postnatal environment before and after training; and explore the feasibility of a contextually appropriate supervision or audit tool.



UK 2026-07-24 11:30:42 2029-07-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Eric Okwir
ID: UNCST-2025-R019992
Greening the tea? Ecolabelling, anticlimax, and the remaking of conservation people in Uganda
REFNo: SS5586ES

Objectives: Main Objective 1. This study interrogates whether and how local tea producers advance beyond the failure of ecolabelling, to adapt its elements into locally-defined environmental ideals that transform tea production and conservation in the KNP landscape. Specific Objectives 1. In what ways do conservation and political-economic processes intersect to produce conditions befitting the introduction of ecolabelling around KNP? 2. How does the nesting of ecolabel discourses with KNP’s contextual discourses produce anticlimax? 3. What rationalities do tea producers draw on to navigate the anticlimax of ecolabelling and does this remake them into new conservation people? 4. In what ways do these alternative rationalities support the transition to more transformative conservation?
Uganda 2026-07-24 10:12:52 2029-07-24 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Hughes David
ID: UNCST-2025-R021951
Hybrid Mobilities in Urban Africa: Congolese Refugees Navigating Environmental Disruption in Kampala, Uganda
REFNo: SS4686ES

Main Objective 1. - To examine how Congolese refugees in Kampala\'s informal settlements navigate environmental flooding through hybrid mobility practices—combining physical movement, digital connectivity, and transnational networks—and how spatial variations between central and peripheral settlements influence livelihood resilience and adaptive strategies. Specific Objectives 1. - To document how environmental flooding events disrupt everyday mobility practices and how refugees adapt to sustain social and economic networks during these disruptions 2. - To analyze spatial and social variations between central (Mengo-Kisenyi) and peripheral (Kawempe I) settlements that influence refugees\' adoption of hybrid mobility strategies and livelihood resilience 3. To examine how gendered, generational, and household dynamics shape refugees’ mobility constraints, risk exposure and adaptive practices during flooding.
UK 2026-07-20 12:12:29 2029-07-20 Social Science and Humanities Non-Clinical Trial Degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
Field clinical evaluation of the point of care diagnostic algorithm combining BBIOxford lateral flow device and Dragonfly molecular diagnostic device for improved Mpox diagnosis in Uganda
REFNo: HS8035ES

Overall Objective
To evaluate the diagnostic performance, operational feasibility, and cost implications of a decentralized two-step mpox point-of-care diagnostic algorithm combining the BBIOxford lateral flow antigen test with the Dragonfly molecular diagnostic platform among clinically suspected mpox patients in Uganda.

Specific Objectives

1. To validate the mpox community testing model at the study sites with key stakeholders.
2. To determine the diagnostic sensitivity, specificity, and predictive values of the BBIOxford rapid diagnostic test alone, the Dragonfly molecular platform alone, and the combined two-step diagnostic algorithm, using PCR as the reference standard.
3. To document and compare the implementation costs of the different diagnostic testing strategies at both per-test and national scale.
4. To identify circulating MPXV clades, detect recombinant strains, and map their prevalence and spatial distribution using PCR and genomic sequencing.
5. To quantify selected MPXV antigens and assess the relationship between antigen load and diagnostic test performance.
6. To assess the operational feasibility, usability, and acceptability of the Dragonfly molecular platform and the two-step diagnostic algorithm among healthcare workers and patients.

Uganda 2026-07-17 19:22:15 2029-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
KOFIH/OPM BUSOGA WASH PROJECT ON WATERBORNE DISEASE REDUCTION AND PREVENTION -AN ENDLINE SURVEY
REFNo: HS8079ES

3.1 General Objective
Assess changes in WASH indicators and waterborne disease outcomes following implementation of project interventions
3.2 Specific objectives
i. Measure project outcomes against baseline data and defined performance indicators;
ii. Evaluate the effectiveness of interventions in improving access to clean water, sanitation, and hygiene practices;
iii. Identify successes, challenges, and gaps in project implementation;
iv. Provide evidence-based recommendations for sustainability, replication, and scaling of interventions;

Uganda 2026-07-17 17:12:16 2029-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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