Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ASUMAN KHAMIS SHAFI
ID:
Timing Of Neurosurgical Intervention And Short-term Outcome Of Patients With Traumatic Brain Injury Admitted To Mulago Hospital Emergency Department
REFNo: HS4610ES

1. To determine the average decision-to-intervention time among patients with TBI admitted at MNRH ED. 2. To determine factors associated with the neurosurgical intervention among patients with TBI admitted to the MNRH ED. 3. To determine the 72-hour outcome mong patients with TBI requiring neurosurgical intervention admitted to MNRH ED.
Uganda 2024-08-26 18:24:09 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Patience Kinengyere Bemanya
ID: UNCST-2024-R004964
PROJECT EVALUATION FOR THE INCREASING EQUITABLE ACCESS TO EFFECTIVE CATARACT SERVICES IN WEST, SOUTH, AND SOUTH-WESTERN UGANDA PROJECT
REFNo: SS2923ES

6. To evaluate the impact on the broader health system, including the referral system and the ability to handle increased demand for eye health services. ,5. To analyse the efficiency of operational processes within the project, including infrastructure development, capacity-building initiatives, and improvements in surgical procedures. ,4. To assess the extent of integrating health services for women with eye care services, its merits and demerits, challenges encountered, and the factors for scalability/sustainability. ,3. To evaluate the project’s success in promoting equity and inclusivity in health service delivery, mainly focusing on gender-specific barriers and access challenges marginalised populations face. ,2. To examine the effectiveness of community engagement strategies and awareness activities in increasing eye health awareness, improving access to services, increasing uptake of eye care services and reducing barriers to access to eye health services.,1. To evaluate overall project impact and effectiveness in terms of increasing equitable access to adequate services, improving service quality, achieving gender equity in eye health and reducing cataract-related blindness in the project area. ,To assess the extent to which the project\'s two components have met their objectives, key outputs, outcomes, and overall impact. It will also validate the monitoring data collected by in-country program teams during implementation. It will contribute to improvement by extracting valuable lessons from each part of the project. These insights will be instrumental in enhancing current and future programming within the region, guiding the development of future projects, and evaluating the potential scalability of the project to improve eye health.,
Uganda 2024-08-26 18:22:11 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
Tailoring community ART delivery to the needs and preferences of people living with HIV in refugee settlements in Uganda
REFNo: HS4193ES

The overarching objective of the proposed study is to evaluate how community ART delivery can be optimized for people living with HIV (PLHIV) in refugee settlements in Uganda.
Specific aims:
Aim 1A: To identify key barriers to community antiretroviral therapy (ART) delivery participation and implementation in refugee settlements experienced by PLHIV, health workers, and expert clients.
Aim 1B: To characterize perspectives of PLHIV, health workers, and expert clients on the optimal design of community ART delivery for refugee settlements.
Aim 2: To quantify community ART delivery preferences among PLHIV in refugee settlements and identify demographic groups with similar preference profiles.

Uganda 2024-08-26 18:17:13 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
Estimating the cost of introduction, delivery and budget impact of malaria vaccine introduction in Uganda (A prospective projection)
REFNo: HS4096ES

4. To determine the budget impact of introducing and delivering Malaria vaccine among children under five years in Uganda. ,3. To estimate and compare the cost of delivering the malaria vaccine under different vaccination modalities/approaches,2. To estimate the additional resource requirements for the introduction and rollout of the malaria vaccine into Uganda’s routine immunizations programme.,1. To explore perspectives of key stakeholders on Uganda’s plan to introduce the malaria vaccine among children under five years.,To estimate the incremental resources (cost) and budget impact of introducing the new malaria vaccine in Uganda to inform the country decision-making regarding the introduction, delivery, national scale-up, as well as impact of the malaria vaccine on other vaccines in the routine immunization system.,
Uganda 2024-08-26 18:14:03 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kisembo Vincent
ID: UNCST-2024-R003679
NATURAL RESOURCE GOVERNANCE AND HUMAN-ECOLOGICAL WELLBEING IN THE OIL AND GAS SUB SECTOR IN BUNYORO SUB-REGION
REFNo: SS2971ES

the study's main objective is to assess natural resource governance and human-ecological wellbeing in the oil and gas sub sector in Bunyoro sub-region, specifically in the districts of Hoima, Kikuube and Buliisa.
Specifically, the study aims to;
1. To analyse the established legal and institutional framework for oil natural resource governance in ensuring the well-being of human -ecological wellbeing in Buliisa, Hoima and Kikuube districts
2. To examine the policies on human wellbeing to the communities in the Oil and Gas sub sector in Buliisa, Hoima and Kikuube districts
3. To analyze the implications of oil and gas sub sector activities on ecological wellbeing in Buliisa, Hoima and Kikuube districts.
4. To examine social and environmental challenges emanating from Oil and gas activities in Buliisa, Hoima and Kikuube districts

Uganda 2024-08-26 15:11:29 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Teopista Akoyi Kevin
ID: UNCST-2024-R004534
AfriFoodLinks Project - Mbale City Research
REFNo: SS2990ES

d. Actively engage government actors, creating a project feedback mechanism. ,c. Engage other project work packages towards constructing positions on multi-level governance, agri-food system entrepreneurship and innovation and urban food environments,b. Actively contribute to development of urban food system researcher network in partner African cities,a. Support the generation of new and path-leading urban food systems knowledge,to generate scientific evidence to inform actions geared towards transforming urban food systems in such a manner that tackles the systemic foundations of food insecurity and environmental impact.,
Uganda 2024-08-26 15:00:52 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Herbert Ainamani Elvis
ID: UNCST-2020-R014674
The Impact of Self Help Plus and Climate Smart Agriculture on Mental Health and Food Security in the Rhino and Nakivale Refugee Settlements of Uganda
REFNo: HS4691ES

To compare the uptake of HGI between the mothers in the combined intervention group (HGI & SH+) with those in the HGI group living in Nakivale refugee settlement,To assess the effect of SH+ on the development of children aged 3-6 years belonging to participating mothers living in Rhino and Nakivale refugee settlements,To assess the effect of SH+ on the mental health of mothers with children aged 3-6 years living in Rhino and Nakivale refugee settlements ,To assess the perceptions and attitudes towards a home gardening intervention (HGI) among participating mothers living in Nakivale refugee settlement,To assess the effectiveness of Self Help Plus (SH+) and home gardening on maternal mental health, food security and child development in the Rhino and Nakivale refugee settlements of Uganda,
Uganda 2024-08-26 14:58:27 2027-08-26 Medical and Health Sciences Clinical Trial Non-degree Award
Richard Mayanja Weazher
ID:
cultural practice and consumption of indigenous iron artifacts of the Baganda people in Uganda
REFNo: SS2942ES

3. To analyze the extent to which indigenous knowledge of ironworks of the Baganda in Central and Southern Uganda has survived.,2. To examine the historical and contemporary relevance of Indigenous iron implements to the Baganda in Central and Southern Uganda.,1. To document the indigenous knowledge embedded in the design production of the indigenous ironworks of the Baganda in Central and Southern Uganda.,The purpose of this study is to document the cultural practice and consumption of the indigenous iron art forms of the Baganda in central and southern Uganda for posterity. ,
Uganda 2024-08-26 14:55:51 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Claire Norcross Valerie
ID: UNCST-2024-R004641
An observational study evaluating archived and emergent HIV drug resistance in people with a history of sub-optimal HIV control in East and Southern Africa
REFNo: HS4761ES

1. To describe archived resistance mutation patterns (major/minor mutations and minority variants) in adults in East and Southern Africa with a recent history of sub-optimal adherence to dolutegravir-based ART; through next-generation sequencing of pro-viral DNA 2. To describe emergent resistance patterns (major/minor mutations and minority variants) in people living with HIV (PLWH) who fail treatment with long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) and the implications for future treatment, and in those who experience blips on LAI-CAB/RPV, through next-generation sequencing on stored plasma 3. To identify predictors of treatment failure on LAI-CAB/RPV in PLWH in East and Southern Africa, and consider how these predictors can influence policy
UK 2024-08-26 14:52:18 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okimait
ID: UNCST-2019-R000095
We Can Work Baseline for Youth With Disability
REFNo: SS3023ES

To provide relevant recommendations and insights that will further inform the program design and adaptation during the implementation period.,To measure all goal, outcome, and output level indicators as a benchmark for purposes of setting performance targets and measurement of the program progress,The overall purpose of this baseline survey is to establish a benchmark of the program indicators across all five outcomes to inform implementation. This will enable systematic measurement of progress towards the intended results annually and at final evaluation,
Uganda 2024-08-26 14:45:41 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
Rapid Assessment of Bottlenecks Inhibiting the Scale-up of Evidence-based Family Planning Practices in Uganda
REFNo: HS4723ES

Broad objective To understand enablers and inhibitors to the scale-up of three EBPs (PPFP, task sharing/expansion, and SBCC) and FP broadly through a BNA approach to inform strategies that can accelerate the uptake of family planning services and programme implementation in Uganda. Specific objectives 1.To synthesize what is known about scaling up FP EBPs and broader FP in Uganda, including implementation status, alignment of guidance with national and international standards, and the lessons learned from successful implementation (including approaches that aim to address gender norms and inequalities) 2.To understand the perspectives of key stakeholders (policymakers, programme managers, healthcare managers, service providers and civil society) on the various health systems factors inhibiting the scale-up of the EBPs. 3.Build consensus among key stakeholders on the most important bottlenecks to EBP scale-up and on solutions that address the root causes inhibiting scale-up
Uganda 2024-08-26 14:41:30 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
What works to prevent and respond to childhood sexual violence in resource-constrained settings: The Case of the 3RT Model implemented by The Remnant Generation in Uganda
REFNo: SS3005ES

4. To study the contribution of girls’ agency in promoting social norms change to prevent childhood sexual violence.,3. To identify critical enablers for effective implementation of interventions to prevent and respond to childhood sexual violence.,2. To explore the role of communities in leading sustainable change for safe environments free from childhood sexual violence. ,To document the effectiveness of the 3RT model in preventing and responding to childhood sexual violence among adolescents in Uganda.,To scientifically examine what works in preventing and responding to childhood sexual violence in resource-constrained settings using the 3RT model of the Remnant Generation as a case. ,
Uganda 2024-08-26 14:40:04 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Warren Aryeija
ID:
Experiences of People with Infertility in Uganda: Empirical Study of Couples with Infertility Challenges at Selected Hospitals in Kampala City
REFNo: SS2807ES

1. Assess knowledge about the causes of infertility among infertile male and female couples. 2. Identify socio-economic challenges experienced by infertile male and female couples. 3. Examine the psycho-emotional impact of infertility on infertile male and female couples. 4. Explore Coping strategies used by infertile male and female couples in living and dealing with infertility. 5. Determine the Socio-demographic correlates of Coping Strategies adopted by infertile male and female couples.
Uganda 2024-08-26 14:21:31 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Monicah Agaba
ID: UNCST-2024-R004221
The Health-Beauty Paradox among Women in Mbarara City Uganda
REFNo: HS4708ES

iii. To characterise the cardio-metabolic profile of WRA.,ii. To document the risk behaviours and their factors related to these societal beauty perceptions.,i. To document societal beauty perceptions and their determinants.,To understand what, why and how the health-beauty paradox is so deeply entrenched in the culture.,
Uganda 2024-08-26 10:18:37 2027-08-26 Medical and Health Sciences Clinical Trial Degree Award
George William Ddaaki
ID: UNCST-2022-R009216
Exploring perceptions, concerns, and perceived benefits of pregnant women and those intending to become pregnant towards participating in HIV cure research.
REFNo: SS2866ES

a) To identify concerns and perceived benefits among women in south central Uganda regarding their participation in HIV cure studies.
b) To explore the perceptions and attitudes of pregnant women and those intending to become pregnant in south central Uganda towards participating in a study focused on impact of pregnancy on the HIV viral reservoir and HIV cure.

Uganda 2024-08-26 10:14:01 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Implementing comprehensive malaria surveillance at sentinel sites in Uganda
REFNo: HS4692ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda.
Uganda 2024-08-26 10:12:47 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
GENDER REFORMS AND POLITICAL SYSTEMS IN UGANDA
REFNo: SS2985ES

The broad objective is to put in context the emerging gender programming reforms in Uganda, particularly the persistent narrative that despite the success in policies that promote women in governance, leadership and employment roles, women voices continue to lag behind.

As a secondary objective, the survey also seeks to increase our understanding of how physical and psychological violence targeting political candidates impacts adult Ugandans’ willingness to engage in electoral politics.


Uganda 2024-08-22 16:38:35 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mutuzo Esther
ID:
Usability Context and Adoption of Human Capital Management Systems in Ugandan Public Universities: Application of the Unified Theory of Acceptance and Use of Technology
REFNo: SS2972ES

Purpose
This study aims to investigate the influence of usability context on the adoption of HCMS in Ugandan Public Universities by using variables from Venkatesh et al.’s (2003) UTAUT theory.

Objectives
The study will focus on the following objectives:
1. To investigate the influence of performance expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
2. To assess the influence of effort expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
3. To investigate the influence of social influence on Ugandan public university staff behaviour intention to adopt HCMS.
4. To examine the influence of facilitating conditions on Ugandan public university staff’s actual use of HCMS.
5. To investigate the influence of Ugandan public university staff behaviour intention on their actual use of HCMS.
6. To investigate the moderating effect of user background characteristics (gender, voluntariness of use, age, and experience) on the relationship between usability context constructs and the adoption of HCMS among Ugandan public university staff.

Research Questions
The study will focus on the following research questions:
1. What are the obstacles impeding the adoption of HCMS in Ugandan public universities, and how can they be addressed?
2. What are the enabling factors facilitating the adoption of HCMS in Ugandan public universities, and how can they be enhanced?

Uganda 2024-08-22 16:35:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jose Rubio Valverde Ricardo
ID:
Evaluation of the Pathways out of Poverty (POP) project in the Kitagwenda and Rakai districts of Uganda
REFNo: SS3052ES


1. Assessing the achievement of objectives: The evaluation aims to assess whether POP\'s objectives are achieved, including increasing household income to $2.25/day, reducing the average household Poverty Probability Index score to 22 or less, and ensuring that 60% of households feel their quality of life has improved within 24 months of each cohort\'s initiation.

2. Estimating causal impact: On priority outcomes for HWG - including grow and net household income, household asset endowment, coffee revenue and profits, best practice adoption and yield – the goal is to determine whether it is possible to establish causal inference on the effects of the program on these variables.

3. Conducting heterogeneous treatment effects analysis: The evaluation will analyze variances in the estimated treatment effect across different demographic groups, with a focus on geographic, economic, social and gender factors.

4. Understanding pathways of change: Core to HWG’s agenda is identifying which project components are vital for driving primary outcomes. The evaluation will aim to dissect the project’s multifaceted initiatives to delineate the most impactful pathways tied to changes in income and agricultural productivity.

5. Determining the importance of coffee: With HWG placing a strong emphasis on the role of coffee in household income, the evaluation will focus on measuring how coffee-centered interventions contribute to the broader project outcomes, tying coffee profit and revenue analyses to holistic changes in income.

6. Identifying unintended consequences: The evaluation should also scrutinize potential negative impacts on the environment, health, human rights, community dynamics, and gender equity, such as the effects of agrochemical use, deforestation, community conflicts, labor issues, and changes in household dynamics and resource control.

7. Suggesting operational improvements: Finally, the evaluation should provide actionable insights and recommendations during the implementation period, to increase the efficacy of POP.

Netherlands 2024-08-22 16:33:12 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSEPH  MURANGIRA
ID:
STRATEGIC MANAGEMENT PRACTICES AND LEGAL CERTAINTY IN UGANDA JUDICIARY
REFNo: SS2917ES

i. To evaluate the effect of strategy formulation on legal certainty in Uganda Judiciary.
ii. To assess the effect of strategy implementation on legal certainty in Uganda Judiciary.
iii. To assess the effect of strategy evaluation on legal certainty in Uganda Judiciary.
iv. To investigate the effect of strategic control on legal certainty in Uganda Judiciary.


Uganda 2024-08-22 16:30:00 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
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