Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Barbara Nayebare Baturaine
ID: UNCST-2025-R021900
AN ASSESSMENT TO UNDERSTAND THE DIFFERENT TARGET AUDIENCE NEEDS (INCLUDING THEIR KNOWLEDGE, ATTITUDES, BELIEFS, AND PRACTICES), AND DEVELOP APPROPRIATE BEHAVIOR CHANGE COMMUNICATION AND MARKETING STRATEGIES
REFNo: SS4464ES

The objective of the survey is to carry out a detailed Knowledge, attitude and Practice survey and design of an evidence-based National FMNR Social Marketing and Behavioral Change Communications Strategy (2023-2028). This document is to be used for communication, marketing and implementation of programs to promote socially beneficial behavior change towards the adoption and scale up of FMNR. This will be informed by primary data collection to inform the development of the strategy.
Uganda 2025-11-04 13:44:41 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
VICTORIA NAKAGIMU MWAZI
ID: UNCST-2025-R020484
FOOD ENVIRONMENT, DIETARY PATTERNS AND NUTRITIONAL STATUS OF SECONDARY SCHOOL TEACHERS IN KAMPALA CITY
REFNo: HS6358ES

To assess the food environment of secondary school teachers in Kampala City, Uganda.
(ii) To analyse the food consumption patterns of secondary school teachers in Kampala City, Uganda.
(iii) To assess the nutritional status and associated factors of secondary school teachers in Kampala city.
(iv) To explore the perceptions of stakeholders on the food environment, diet and the nutritional status of secondary school teachers in Kampala City.

Uganda 2025-11-04 13:42:47 2028-11-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Opportuna Kweka Leo
ID: UNCST-2025-R021025
STRENGTHENING KNOWLEDGE, EVIDENCE USE AND LEADERSHIP IN THE GLOBAL SOUTH ON FORCED DISPLACEMENT: WITH A FOCUS ON EAST AFRICA
REFNo: SS4309ES

Conduct research on forced displacement, namely refugees, internally displaced persons and development/conservation/disaster and climate changed induced displacement). (ii) Build capacity on forced displaced issues through seminars, training of masters, PhD and postdoctoral students doing research on forced displacement. (iii) Work with policy makers to discuss the state of the knowledge, constraining factors and possible angles for inclusion of those marginalized. (iv) Work with NGOs to conduct outreach activities either expanding and upscaling existing outreach activities (originating from refugees or external actors) or start new empowerment programmes on social and legal inclusion. (v) Develop a master’s programme on forced displacement, which will be offered in the Department of Geography at the University of Dar es Salaam
Tanzania 2025-11-04 13:40:10 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Alinda
ID: UNCST-2025-R020482
PHYSICAL PLANNING AND URBANIZATION IN UGANDA: A CASE OF FORT PORTAL CITY, CENTRAL DIVISION
REFNo: SS4377ES

General Objective (Purpose) of the Study The study is to evaluate the effect of physical planning on urbanization in Fort Portal City, Uganda. Specific Objectives of the Study i.To assess the effect of Urban Design on urbanisation in Fort Portal City. ii.To examine the influence of Enforcement Mechanism on Urbanisation in Fort Portal City. iii.To evaluate the contribution of Monitoring & Evaluation on urbanisation in Fort Portal
Uganda 2025-11-04 13:37:44 2028-11-04 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Amplifying Community Voices and Lived Experience of the Perceived Impact of Climate Change on Health among Community Health Workers in Namayingo District, Uganda
REFNo: SS4546ES

1.Document CHW experiences of the intersection between climate change and health among individuals, families, and communities.
2.Assess CHW experiences of how climate change affects their role and the health system more broadly.
3.Describe CHW perspectives on community strength and resilience in the face of the climate crisis, including local solutions.
4.Explore CHW recommendations for developing a climate-informed health workforce and climate-resilient health systems and communities.
Uganda 2025-11-04 13:34:31 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Prosper Behumbiize
ID: UNCST-2025-R019986
Uganda’s Digital Mental Health Leap Harnessing DHIS2 for Data-Driven Insights
REFNo: HS6407ES

The project seeks to address Uganda's mental health data quality, access and utilisation gap by leveraging the DHIS2 platform to digitise the depression and anxiety facility data pipeline, from data generation to analysis and insight generation. Primary objectives The specific objectives are; - Create a harmonised, digitised dataset to enable access of individual granular longitudinal mental health data. - Design and deploy an open-access digital tool and dataset repository to ensure transparency, scalability, and ease of access to analytical outputs. - Engage stakeholders in capacity-strengthening activities. Secondary objectives - Conduct secondary data analysis using open-source Artificial Intelligence (AI) and Machine Learning (ML) models to derive actionable insights from standardised datasets. - Generate policy-relevant outputs, including dashboards, open-source publications, and policy briefs, to inform decision-making at various levels.
Uganda 2025-11-04 13:33:24 2028-11-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HOPE KANSIIME
ID: UNCST-2024-R004499
Designing an optimised framework for effective usage and efficient access of Electronic resources in the consortium of Ugandan university libraries
REFNo: SIR561ES

To establish the acceptability and usability of the developed framework designed to enhance the access and usage of e –resources within the consortium of Uganda university libraries,To design and develop an optimised framework aimed at improving the accessibility and utilization of e-resources within the consortium of Uganda university libraries,To determine the necessary prerequisites for creating an optimized framework that will improve the accessibility and utilization of e-resources in the consortium of Uganda university libraries?,To conduct a cross-sectional study to evaluate how E-resources are utilised, examine access patterns and identify barriers and challenges to their usage within the consortium of Uganda university libraries,To optimise Electronic resource utilisation in Ugandan university consortium by developing an efficient access and usage framework,
Uganda 2025-11-04 13:31:17 2028-11-04 Engineering and Technology Non-Clinical Trial Degree Award
Edwin Nuwagira
ID: UNCST-2021-R013488
Improving Diagnostic Strategies for Post-Tuberculosis Lung Disease in Ugandan Primary Health Care Settings (IMPULSE-TB)
REFNo: HS6402ES

To test the feasibility and acceptability of the diagnostic algorithm in facilitating timely post-TB lung diseasediagnosis at primary healthcare facilities,To use qualitative methods to identify barriers and facilitators of diagnosis to post-TB lung disease,To develop, test and validate a clinical algorithm for diagnosing post-TB lung disease based on clinical and sociodemographic characteristics,
Uganda 2025-11-04 13:29:51 2028-11-04 Medical and Health Sciences Non-degree Award
Francis Pebalo Pebolo
ID: UNCST-2022-R010630
Incidence, risk factors and clinical outcomes of neonatal sepsis among HIV-exposed infants of mothers on dolutegravir-based antiretroviral therapy in Uganda
REFNo: HS6486ES

Comparing 28-day clinical outcomes of mothers with HIV on DTG-based ART compared with their HIV negative counterparts.,To compare 28-day clinical outcomes among HIV-exposed neonates of mothers on DTG-based ART and HIV-unexposed neonates.,To compare sepsis incidence risk factors among HIV-exposed neonates of mothers on DTG-based ART and HIV-unexposed neonates,To conduct a scoping review to describe the epidemiology of neonatal sepsis of neonates born to mothers with HIV comparing outcomes on DTG- and non-DTG-containing regimens,
Uganda 2025-11-04 13:00:07 2028-11-04 Medical and Health Sciences Degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
Phase I/II Dose Finding, Safety and Tolerability Study of Daily Rifapentine Combined with Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age with and without HIV
REFNo: HS6555ES

Primary Objectives
Cohort 1 and Cohort 2
• To determine the weight-band dosing of RPT taken as part of the 1HP regimen by evaluating:
⎯ PK RPT exposures among children with and without HIV
⎯ Safety and tolerability of the 1HP regimen among children with HIV while receiving twice-daily DTG and children without HIV through 28 days of dosing
Cohort 2
• To evaluate the effect of RPT taken as part of the 1HP regimen on the PK of DTG
Secondary Objectives
Cohort 1 and Cohort 2
• To evaluate the effect of covariates including age, weight, sex, ethnicity, nutritional status, and HIV-1 status on the PK of RPT taken as part of the 1HP regimen
• To evaluate the safety of the 1HP regimen through 24 weeks of follow-up
• To evaluate the palatability and acceptability of the 1HP regimen
• To evaluate adherence to the 1HP regimen
Cohort 2
• To evaluate the safety and tolerability of twice-daily DTG through 42 days among children with HIV who are receiving 1HP
• To evaluate virologic control (less than 200 copies/mL) at Day 42 among children taking a DTG-based ARV treatment regimen co-administered with 1HP

Uganda 2025-11-04 12:59:17 2028-11-04 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ConfiSign HIV/Syphilis Combo Self-Test: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6687ES

Untrained users will either take part in the label comprehension study and results interpretation study (part A) or in the observed untrained user study (part B). Untrained users enrolled for the label comprehension and results interpretation study (part A), shall not participate in the observed user study (part B) and vice versa.,The primary and overall objective of this study is to evaluate the performance and the usability of the ConfiSign HIV/Syphilis Combo Self-Test in the hands of untrained users from a low prevalence HIV region (< 5%) who have no, or limited experience in self-testing. ,
Uganda 2025-10-29 16:22:26 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Specioza Namakula
ID: UNCST-2025-R021710
EMPOWERING MOBILITY: Assessing the Impact of Buffalo Bicycles on Refugee and host Communities in Uganda. A case study of Bidi Bidi, Rhino Camp and Palabek refugee settlements
REFNo: SS4566ES

I. To generate data that will support Learning and evidence-based decision making.
II. To provide systematic and objective information for bicycle usage in refugee communities.
III. Generating information that is required to inform advocacy and further bicycle provision for vulnerable communities.
IV. To determine the effectiveness, efficiency and relevance of bicycles in improving accessibility to essential services like education, health and economic empowerment.
Uganda 2025-10-29 16:20:00 2028-10-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victor Musiime
ID: UNCST-2021-R013794
Enhancing Novel Research for Inflammation and Cognitive Health among Adolescents and Young Adults Living with Perinatally Acquired HIV and Adversity (ENRICH+)
REFNo: HS6607ES

Specific Aim 1: Investigate differences in ID and NCI in demographically matched, virally suppressed PHIV and HHIV, as well as HUU AYA (15-25 years old) in Uganda while controlling for chronic adversities. Hypothesis 1 (H1): Both ID and NCI will be respectively higher in PHIV vs. HHIV vs. HUU AYA. H2: Within the two HIV groups, those with delayed ART initiation and lower nadir CD4 cell count at ART initiation will have higher ID and worse NCI.

Specific Aim 2: Investigate the relationship between ID and NCI in AYA within all three groups (PHIV, HHIV and HUU) controlling for chronic adversities. H3: There will be a positive association between ID and NCI in each group. H4: In a subset of PHIV and HUU AYA with prior repeated measures of ID, worsening trajectories of ID in PHIV across 6 years will be associated with worse NCI.

Specific Aim 3: Investigate the effects of co-occurring adversities (i.e., profiles) on the relationships between HIV, ID, and NCI. H5: Adversity profiles will be more severe respectively in PHIV vs. HHIV vs. HUU. H6: The strength of association between medical and psychosocial (e.g., stigma, mental health) adversities, ID and NCI will be strongest in PHIV vs. HHIV vs. HUU, respectively.


Uganda 2025-10-29 16:07:10 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
A5402 An Open-Label, Randomized Controlled Trial of Pramipexole versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD with Mild Neurocognitive Disorder (MND) in Persons with HIV
REFNo: HS6604ES

1.2 Primary Objectives

1.2.1 To compare pramipexole to escitalopram in the treatment of MDD (and comorbid MDD with MND) based on the Beck Depression Inventory-II (BDI-II/BDI-2) total score [Beck 1996] from baseline to week 24.

1.2.2 To evaluate the safety of pramipexole and escitalopram in PWH having MDD (and comorbid MDD with MND) from baseline to week 24.

1.3 Secondary Objectives

1.3.1 To compare pramipexole to escitalopram in the treatment of MDD using MDD caseness, neurocognitive outcomes, and functional status from baseline to week 24.

1.3.2 To compare the depression, neurocognitive, and functional status outcomes in PWH with MDD alone and with comorbid MDD with MND treated with pramipexole versus escitalopram from baseline to week 24.

1.3.3 To compare the impact of pramipexole and escitalopram on all outcomes above by female versus male sex (assigned at birth) from baseline to week 24.

1.3.4 To determine the impact of pramipexole compared to escitalopram on the measure of HIV-1 RNA viral load in the peripheral blood.

1.4 Exploratory Objectives

1.4.1 To characterize associations between escitalopram trough concentrations and treatment efficacy (BDI-II/BDI-2 total score) as well as participant adverse events (adverse event frequency, severity, and discontinuation rates).

1.4.2 To characterize associations between escitalopram trough concentrations and genetic polymorphisms that affect metabolizing enzymes of escitalopram (known metabolizing enzymes include CYP2C19, CYP2D6, and CYP3A4).

1.4.3 To explore associations between cerebrospinal fluid (CSF) concentrations of escitalopram and BDI-II/BDI-2 total score.

1.4.4 To evaluate adverse events potentially related to drug interactions between antiretroviral therapy (ART) and escitalopram and pramipexole, respectively.

1.5 Substudy Objective

1.5.1 CSF Substudy

To compare the impact of pramipexole and escitalopram on biomarker outcomes in a CSF substudy of participants with MDD alone.

Uganda 2025-10-29 16:04:25 2028-10-29 Medical and Health Sciences Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Dihydroartemisinin-piperaquine plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone for the prevention of febrile illnesses in children with sickle cell anemia: a double-blind randomized controlled trial
REFNo: HS6294ES

1.
To compare the incidence of all-cause febrile illness among children with sickle cell anemia randomized to receive monthly SP vs. monthly DP+SP.
2.
To compare the incidence of adverse events among children with sickle cell anemia randomised to receive monthly SP vs. monthly DP+SP.
3.
To compare the prevalence of markers of antimalarial resistance, including those associated with SP and DP resistance, among parasitemic children with sickle cell anemia randomized to receive monthly SP vs. monthly DP+SP.
Uganda 2025-10-29 15:55:44 2028-10-29 Medical and Health Sciences Clinical Trial Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
Peerled Dynamic Choice HIV Prevention for Women. The Peer-led DCP Study
REFNo: HS6556ES

To refine and pilot test a Peer-led Dynamic Choice HIV Prevention intervention for women at elevated HIV risk in southwestern Uganda
Uganda 2025-10-29 12:53:43 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Tusabe Not Applicable
ID: UNCST-2025-R022045
EXPLORING THE IMPLEMENTATION OF EARLY GRADE READING METHODOLOGY IN UGANDA PRIMARY SCHOOLS
REFNo: SS4540ES

1.3.1 Main Objective

To explore the implementation of Early-Grade Reading Methodology in primary schools in Uganda.

1.3.2 Specific Objectives

To establish the current practices of Early-Grade Reading methodologies by teachers in primary schools in Uganda.

To identify the challenges teachers face in implementing Early-Grade Reading methodologies in their classrooms.

To determine strategies that can be adopted to improve the implementation of Early-Grade Reading methodologies in Ugandan primary schools.
Uganda 2025-10-29 12:51:10 2028-10-29 Social Science and Humanities Non-Clinical Trial Degree Award
richard kasirye
ID: UNCST-2025-R018157
Instructional Technologies for Teacher Education at Busitema University: Application of Skills to Practice
REFNo: SS4450ES

The study aims to answer: How do Busitema University’s teacher education alumni apply ICT knowledge and skills in the secondary schools where they teach? What are their experiences in using ICT in their classrooms? How can the university improve the teacher education program to better prepare graduates for technology-enhanced teaching?
Uganda 2025-10-29 12:48:06 2028-10-29 Social Science and Humanities Non-Clinical Trial Degree Award
ALEX KAYONGO
ID: UNCST-2019-R001641
Clonotyping Airway T-cells to Uncover Microbiome-Specific Inflammotypes in HIV-Associated COPD
REFNo: HS6625ES

Study Aim:
To investigate the airway microbiome-specific inflammotypes in COPD among HIV-infected individuals in a rural Uganda.

Specific objectives
1.To determine, in vitro, the CD4+T-cell clonotypic library specific to airway bacterial species associated with COPD among HIV-infected individuals in rural Uganda.

2.To determine, ex vivo, the microbiome-specific clonotypic landscape of BAL-derived CD4+T cells from a cohort of individuals stratified by HIV and COPD in rural Uganda.

3.To validate airway microbiome-specific inflammotypes among individuals with COPD transitioning from stable disease to exacerbation and back to stable disease.

Uganda 2025-10-29 12:47:04 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AGNESS NATABA
ID: UNCST-2024-R002018
Reclaiming Rights:Bunyoro Kitara Kingdom Women and their Quest for Reparative Justice from British Colonialism
REFNo: SS4501ES

1. To examine how historical injustices faced by women in the Bunyoro Kitara Kingdom during British colonial rule affected their cultural setting. 2. To evaluate existing reparative justice efforts for women in the Bunyoro Kitara Kingdom. 3. To assess how gender-responsiveness the existing reparative efforts are in fostering inclusive justice, healing, and environmental justice for women in the Bunyoro Kitara Kingdom.
Uganda 2025-10-29 12:44:59 2028-10-29 Social Science and Humanities Non-Clinical Trial Degree Award
JACOB BIBOHERE
ID: UNCST-2025-R021298
Assessment of CDC Data Triangulation Activities to Enhance Immunization and Vaccine-Preventable Disease Surveillance Programs in Selected African Countries
REFNo: HS6596ES

1.To assess the extent to which data triangulation has been integrated into the existing immunization and/or VPD surveillance staff workload, program processes, and practices at national and sub- national levels. 2.To identify programmatic successes, challenges, enabling factors, and innovations reported by immunization and/or VPD program staff through the application of triangulation analytic tools. 3.To examine the immunization programmatic decisions, actions, and outcomes that have been informed by the use of data triangulation concepts. 4.To explore and identify sustainability strategies and recommendations for ensuring that data triangulation and existing tools remain integrated into routine program activities.
Uganda 2025-10-29 12:42:52 2028-10-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shivan Kamugisha Kaitesi
ID: UNCST-2025-R019815
Socio-Ecological Systems Assessment of Factors Influencing the Lion population in the Greater Virunga Landscape
REFNo: NS989ES

1. Develop a population dynamics model for lions in the Greater Virunga Landscape 2. Assess the functionality of lion movement corridors within GVL 3. Examine the impacts of land use and climate change on the suitable habitat for lions 4. Evaluate factors of human-lion conflict and develop strategies for conflict mitigation and coexistence.
Uganda 2025-10-29 12:41:40 2028-10-29 Natural Sciences Non-Clinical Trial Degree Award
Michael Harvey
ID: UNCST-2025-R022115
HERPETOFAUNAL DIVERSITY AND BASELINE ECOLOGICAL ASSESSMENT IN SELECT SITES OF NORTHERN AND WESTERN UGANDA
REFNo: NS1049ES

• Generate a list of reptiles and amphibians inhabiting Mount Kadam and surrounding areas
• Compare the distributions of reptiles and amphibians across different habitats within the boundaries of the research site.
• Establish a reference collection of vouchered specimens from the reserve in a local international research collection/museum.
• Tabulate baseline ecological data for each species (see data collection for details)
• Involve local community, students, and other stakeholders in survey methods and data recording
• Publish results of survey in peer-reviewed scientific journals

USA 2025-10-24 17:36:31 2028-10-24 Natural Sciences Non-Clinical Trial Non-degree Award
DENISH  ONGOL OGWANG
ID: UNCST-2025-R022077
THE IMPLEMENTATION OF THE PRISONERS’ RIGHT TO VOTE IN UGANDA. A CASE STUDY OF LUZIRA PRISONS, 1995-2021
REFNo: SS4502ES

1. To assess the adequacy of the legal framework for the implementation of prisoners’ right to vote in Uganda.
2. To identify the challenges that Luzira Prisons face in the implementation of the prisoners’ right to vote
3. To develop a framework for the implementation of the prisoners’ right to vote in Uganda.

Uganda 2025-10-24 17:35:10 2028-10-24 Social Science and Humanities Non-Clinical Trial Degree Award
Mudarshiru Bbuye
ID: UNCST-2025-R019080
EXPLORING THE ASSOCIATION BETWEEN AIR QUALITY AND THE BURDEN OF RESPIRATORY TRACT INFECTIONS IN KAMPALA, UGANDA
REFNo: HS6603ES

General objective To explore the impact of ambient air pollution on the incidence, prevalence, and severity of respiratory tract infections, and the extent of enforcement of air quality control policies and regulations in Kampala, Uganda, a low-resourced urban setting Specific Objectives 1.To conduct a systematic review and meta-analysis to quantify the association between ambient air pollution and respiratory tract infections in low- and middle-income countries (LMICs). 2. To characterise the spatial variation in ambient PM2.5 exposure and its correlation with respiratory tract infection health effect among sub-populations in Kampala, Uganda 3.To determine the effect of air quality policies and regulations on the long-term ambient PM2.5 levels and the respiratory tract infections health effects in Kampala, Uganda. 4. To explore the limitations of adaptation and enforcement of air pollution control policies and regulations to reduce the ambient air pollution health effects in Kampala, Uganda.
Uganda 2025-10-24 17:34:12 2028-10-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Dr. James Wasike Mangeni Byanasaye
ID: UNCST-2020-R008019
DENTAL ANTIMICROBIAL STEWARDSHIP IN UGANDA - DEVELOPING AN EVIDENCE BASED INTERVENTION
REFNo: HS6561ES

Aim: To develop evidence-based, behaviour science informed antimicrobial stewardship intervention aimed at reducing antibiotic prescribing to adult patients for dental issues.
Objectives:
1. To understand the factors that influence antibiotic prescribing by health care practitioners to adult patients for dental issues.
2. To explore the perspectives of patients seeking dental care on the use of antibiotics for dental issues.
3. To explore community stakeholders' perspectives on the use of antibiotics for dental issues
4. To co-produce an evidence-based, behaviour science informed dental antibiotic stewardship intervention for Uganda.


Uganda 2025-10-24 17:32:56 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Deogratius Ssemwanga
ID: UNCST-2025-R021563
Performance Evaluation for Diagnostic Tests
REFNo: HS6649ES

Primary Objective

The overall objectives of this performance evaluation are:

• To verify the performance characteristics of new on-the-market NAATs and antigen RDTs.
• To establish well-characterized viral pathogen sera/plasma reference panels to support evaluation efforts and quality assurance.

• To evaluate the performance characteristics of new, on-the-market, EIAs and RDTs (IgA, IgG and IgM).
• To train laboratory and POC staff in biosecurity and the required technical skills to perform diagnostic testing.

Specific Objectives:

• To confirm whether or not a new NAAT complies with the manufacturer’s specifications,
• To determine the performance equivalence of new on-the-market NAATs, including POC devices, using available gold standards (or any other comparatively/equally as good WHO/FDA approved NAAT),
• To determine the performance equivalence of new on-the-market antigen tests against the gold-standard NAAT,
• To determine the sensitivity and specificity of new on-the-market diagnostic EIAs and RDTs against a gold-standard method,
• To evaluate the operational characteristics of new on-the-market immunoassays. Operational utility characteristics that may be considered include;
o ease of performance
o specimen type utility
o inter-reader variability
o reaction endpoint stability
o suitability for use in facilities with limited infrastructure (no/limited electricity, no/limited clean water)
• To document SOPs and train laboratory staff in performing testing using recommended diagnostic tests,
• To establish a repository of well-characterized natural infection and vaccination sera/plasma as well as swabs/extracted RNA to support future evaluation and verification of immunoassays.
• To establish a cohort of natural infection and vaccinated cases in the country whose samples and demographic characteristics will be used to help understand the dynamics of human immunity development to viral infection in order to inform the clinical interpretation of the various diagnostic assays.

Uganda 2025-10-24 17:31:36 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Muzanyi
ID: UNCST-2021-R013731
Exploration Of the Correlation Between Active TB Immunological Markers and Sputum Culture: A Cytokine TB (CYTO-TB) Study
REFNo: HS6426ES

Main Objective
1. To explore the correlation of TB immunological markers (IL-2, IL-2Ra, I-P10, MIP-β, MCP-1) and TB sputum cultures at five-time points: before the start of treatment (Month 0), then Months 1, 2, 5, and 6.
Specific Objectives
1. 1. To assess the level of each or a combination of cytokines at the time points of active TB diagnosis, months 1, 2, 5, and 6, and how they relate to sputum culture on liquid (days to positivity) and solid (quantitative colony counts) media
2. 2. 2. To assess the baseline level of each cytokine or a combination and how it correlates with (a) the clinical response to TB treatment at months 1, 2, 5, and 6; (b) the clinical severity, and radiographic extent (severity) of TB disease at diagnosis and end of treatment.
3. 3. To evaluate the differences in the TB cytokine levels between active and latent TB during treatment with ERHZ (for active TB), and 6H (for latent TB), stratified by HIV status
4. 4. To evaluate the TB cytokine levels across three populations of active TB, Latent TB, and TB-exposed healthy volunteers who are TST/IGRA negative
5. 5. To compare the cost-effectiveness of TB immunological markers against sputum culture (standard of care).
Uganda 2025-10-24 17:30:54 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
UNDERSTANDING INFECTIOUS AND NON-INFECTIOUS DISEASE TRENDS IN KANUNGU DISTRICT TO INFORM PUBLIC HEALTH PLANNING AND INTERVENTIONS
REFNo: HS6462ES

1. Determine types and trends of diseases in Kanungu from 2015–2025.
2. Compare quality and quantity of HCF records with MoH’s DHSI data.

Uganda 2025-10-24 17:28:54 2028-10-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Agatha Nakibuule Martha
ID: UNCST-2024-R016574
EXPLORING HIV SELF-TESTING: PERCEPTIONS AND EXPERIENCES OF SEX WORKERS AND MALE CLIENTS ON KOOME ISLAND, UGANDA
REFNo: HS6306ES

1.3 Objectives
1.3.1 General objective
The overall objective of this study is to increase the adoption and use of HIVST kits among sex workers and their clients on Koome Island, by qualitatively exploring their perceptions, preferences and experiences of using HIVST kits for HIV prevention, and assessing how HIVST may influence status disclosure, behaviour change and linkage to care.
1.3.2 Specific objectives
1. To explore the perceptions, preferences and experiences of HIV self-testing among sex workers on Koome Island.
2. To explore the perceptions, preferences and experiences of HIV self-testing among male clients of sex workers on Koome Island.
3. To assess perceptions, practices, and norms of sex worker peers and healthcare providers that may influence HIVST scale-up and implementation for sex workers and their clients in island fishing communities.


Uganda 2025-10-24 17:27:53 2028-10-24 Medical and Health Sciences Non-Clinical Trial Degree Award
MUGISHA BRIAN
ID: UNCST-2025-R017969
Evaluating Health Workers' Competence in Utilizing Electronic Health Records Systems for Quality Service Delivery in Hospitals: Greater Bushenyi, Uganda
REFNo: SIR541ES

Major Objective
-The purpose of this study is to Evaluate Health Workers' Competence in Utilizing Electronic Health Records Systems for Quality Service Delivery in Selected Hospitals in Greater Bushenyi, Uganda.

Specific Objective
1.To establish the current state of Electronic Health Records within hospitals in the Greater Bushenyi region, Uganda.
2.To establish essential requirements for the development of a comprehensive framework model, focusing on the evaluation of effective usage of EHRs.
3.To develop a competence-based framework tailored for evaluating the usage of EHRs in hospitals in the Greater Bushenyi region, Uganda.
4.To Evaluate and validate the effectiveness of the developed framework for assessing EHRs within hospitals in the Greater Bushenyi region, Uganda.

Uganda 2025-10-24 17:15:31 2028-10-24 Engineering and Technology Non-Clinical Trial Degree Award
AISHA NAJJUMA
ID: UNCST-2025-R017830
CONFLICT RESOLUTION STRATEGIES AND ACADEMIC STAFF PERFORMANCE OF PRIVATE CHARTERED UNIVERSITIES IN KAMPALA, UGANDA
REFNo: SS4149ES

i) To evaluate the effect of competitive strategy on academic staff performance of private chartered universities in Kampala, Uganda ii) To examine the effect of collaborative strategy on academic staff performance of private chartered universities in Kampala, Uganda iii) To assess the effect of accommodating strategy on academic staff performance of private chartered universities in Kampala, Uganda iv) To examine the effect of negotiation strategy on academic staff performance of private chartered universities in Kampala, Uganda v) To evaluate the effect of confrontation strategy on academic staff performance of private chartered universities in Kampala, Uganda. vi) To assess the moderating effect of leadership styles in the relationship between conflict resolution and academic staff performance of private chartered universities in Kampala,
Uganda 2025-10-24 17:10:26 2028-10-24 Social Science and Humanities Non-Clinical Trial Degree Award
Peter  Babyenda
ID: UNCST-2023-R007975
Energy Demand and Efficiency among Households and Small and Medium Scale Industries in Uganda
REFNo: SS4418ES

To understand the interlinkages in energy demand, efficiency, and productivity of households and small and medium-scale industries in Uganda.,Determine the impact of energy efficiency on Productivity of Households and Small and Medium Scale Industries. ,Identify the determinants of energy efficiency among small and medium scale industries in Uganda. ,Establish factors influencing energy demand and efficiency among households in Uganda ,
Uganda 2025-10-21 9:27:02 2028-10-21 Social Science and Humanities Non-degree Award
Alen Musisi
ID: UNCST-2022-R009338
Exploring the Frequency and Perceived Scope of Radiation Protection Information in Continuous Medical Education Among Radiation Workers in Uganda
REFNo: HS6455ES

To explore the frequency and perceived scope of radiation protection information provided through continuous medical education programs for radiation workers in Uganda
Uganda 2025-10-21 9:22:28 2028-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Park
ID: UNCST-2025-R019397
Global Governance, Ecojustice and the Independent Accountability Mechanisms
REFNo: SS4370ES

This project uses an eco-justice frame to analyse publicly available submissions by communities seeking recourse for environmental and social harm as a result of the pipeline financed by the World Bank Group and the Multilateral Development Banks (MDBs) to investigate whether they lead to improvements for people and ecosystems at project sites.
Australia 2025-10-21 9:17:15 2028-10-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alex Semusu
ID: UNCST-2025-R018018
CREDIT RISK MANAGEMENT POLICIES AND LOAN PERFORMANCE IN THE BANKING SECTOR OF CENTRAL UGANDA
REFNo: SS4123ES

1.4 General Objectives
To investigate the relationship between Credit Risk Management Policies and Loan Performance in the banking sector in Central Uganda.
1.4.1 Specific Objectives
i. To assess the relationship between the Credit Limit policy and Loan Performance in the banking sector of Central Uganda.
ii. To explore how the Credit Collection policy relates to Loan Performance in the banking sector of Central Uganda.
iii. To investigate the relationship between Credit Monitoring policy and Loan Performance in the banking sector of Central Uganda.
iv. To ascertain the influence of government policies on credit risk management policies and loan performance in the banking sector of Central Uganda.

Uganda 2025-10-21 9:10:22 2028-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Kyambadde Ronald
ID: UNCST-2025-R016678
HIGH DOSE VS STANDARD DOSE CAFFEINE THERAPY FOR APNEA OF PREMATURITY: A RANDOMISED CONTROL TRIAL.
REFNo: HS5776ES

To compare the efficacy and safety of high-dose caffeine citrate (loading dose 40 mg/kg/day, and maintenance of 20mg/kg/day), versus standard dose (loading dose of 20 mg/kg/day, maintenance of 10mg/kg/day), in preventing the occurrence and reducing the frequency of apneas among preterm infants ≤ 34 weeks’ gestation with Apnea Of Prematurity in the first 7 days of life.


Specific Objectives

1. To determine the effect of high dose compared to standard dose of caffeine on the incidence of apnea of prematurity among preterm babies at St. Francis Hospital, Nsambya, and Uganda
Martyrs’ Hospital Lubaga.

2. To determine the side effects of high dose compared to standard dose caffeine in preterm infants.
Uganda 2025-10-21 9:08:50 2028-10-21 Medical and Health Sciences Clinical Trial Degree Award
Sulaiman Kiggundu
ID: UNCST-2025-R017887
Enhancing early childhood education through use of low-cost instructional resources: A case study in Nsangi subcounty, Wakiso district.
REFNo: SS3748ES

Understanding how best to support ECD teachers in using low-cost instructional resources Explore strategies for supporting ECD teachers in Nsangi Subcounty to effectively utilize low-cost instructional resources
Uganda 2025-10-21 9:05:46 2028-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Raymond  Chisara
ID: UNCST-2024-R004454
Digital Business Leadership Framework for Successful Digital Transformation In Africa: A Case Study of African Companies
REFNo: SS3647ES

Main Objectives
1. To develop a digital business leadership framework for Africa. Delete
Specific Objectives
1. To conceptualise digital business leadership in Africa. Delete
2. To critically review the impact of values and culture on digital business leadership in Africa Delete
3. To compare digital leadership in Africa and the rest of the world. Delete
4. To discover the challenges faced by digital leaders in Africa. Delete
5. To analyse the impact of extreme contexts on the emergence, viability, and sustainability of digital leadership in Africa.

Zimbabwe 2025-10-21 9:02:19 2028-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Allen Kabagenyi
ID: UNCST-2019-R000665
An Empirical Evaluation of The Impact of The Pre-entry Exams at Makerere University School of Law: A Case Study of The Legal, Policy and Regulatory Implications
REFNo: SS4301ES

1. The overall performance of students at MAKSOL in the five academic years since inception of the pre-entry exams in academic year 2012/13
4 (in comparison to overall performance in the five academic years preceding academic year 2012/13)
2. Any correlation (whether positive or negative) between the top percentile
of the pre-entry exam and the top percentile of the CGPA at graduation from MAKSOL;
3. To infer as to whether the relationship between pre-entry exams and FYGPA is consistent across the subsequent academic years for the
different cohorts of the enrollees.
4. To explore the trainers and students’ perceptions and attitudes towards
pre-entry exams assessment as s requirement for admission into the MAKSOL
5. To examine the extent of diversity in admission based on the schools which have sent students to MAKSOL and to compare this with the
diversity prior to the introduction of the pre-entry exam.
Uganda 2025-10-21 9:00:06 2028-10-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Herbert Ainamani Elvis
ID: UNCST-2020-R014674
Exploring the Psycho-therapeutic Approaches utilized by Psychotherapists practicing from in Central and Western Uganda
REFNo: SS3492ES

To understand Psychological approaches utilized by psychotherapists in Uganda and how these approaches these therapies have been adapted to suit the Ugandan culture,4.4. To understand how the Ugandan Psychotherapists have modified the western therapies to suit the Ugandan culture,3. To explore Psychotherapeutic treatment approaches utilized by Psychotherapists in western and central Uganda ,2. To understand the common mental health disorders diagnosed by psychotherapists in western and central Uganda. ,1. To explore Psychotherapeutic treatment approaches utilized by Psychotherapists in western and central Uganda ,To understand how the Ugandan Psychotherapists have modified the western therapies to suit the Ugandan culture.,To explore Psychotherapeutic approaches utilized by Psychotherapists in Uganda,1)To evaluate the baseline knowledge of diagnostic procedures and various treatment approaches used by Psychotherapists in Uganda.,
Uganda 2025-10-21 8:55:28 2028-10-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gloria Abura-Meerdink Akello
ID: UNCST-2023-R007309
A Community Engaged Approach to Investigating the Transferability of Youth Readiness Intervention (YRI) for Adolescents facing Adversity in Post conflict School-Based Settings in Northern Uganda: Barriers and Strategies to Increase Adoptability, Acceptability, and Usefulness
REFNo: SS4496ES

To identify barriers and strategies to inform a culturally sensitive and context-appropriate adaptation of YRI for adolescents in Northern Uganda. ,To develop a regional Youth Mental Health Research-Community-Practice-Policy Collaborative in Northern Uganda that includes youth and multi-disciplinary stakeholders from communities, schools, and regional education and mental health systems (n = 10). ,
Uganda 2025-10-20 11:54:44 2028-10-20 Social Science and Humanities Non-degree Award
Yueh-ya Hsu
ID: UNCST-2025-R021249
The Impact of Microcredit for Refugees and Host Communities
REFNo: SS4473ES

The aim of this project is to provide some of the first evidence on the benefits of extending credit to refugees, with a focus on documenting both financial and psychosocial gains. The team's close partnership with the UNHCR and the World Bank ensures that the results can be quickly disseminated to key actors in this space. UNHCR operates in over 136 countries and collaborates closely with implementing partners to develop and disseminate impactful programs. They are eager to build a body of evidence to inform the pursuit of certain policies over others, and facilitate discussions with local governments about implementing these policies.
Taiwan 2025-10-17 19:36:16 2028-10-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Phillip Kasirye Kasirye
ID: UNCST-2022-R011083
mHealth-enabled User-friendly Light-based Stroke Screening and Assessment in Pediatric Sickle Cell Disease in Uganda (MULISA)
REFNo: HS6657ES

1. Evaluate the preliminary performance of CW-NIRS/SCOS in children with sickle cell disease
2. Identify user needs to inform the design of a mobile health-enabled stroke screening tool.

Uganda 2025-10-17 19:33:45 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
Vitamin D and Gut Microbiota and Dementia rick in older adults with chronic HIV infection and demographically matched community controls. Adverse Synergy of Gut Dysbiosis and Vitamin D Deficiency in Alzheimer’s Disease and Related Dementia among Community Controls and Older Adults with Chronic HIV-infection
REFNo: HS6600ES

2) To interrogate the potential for heightened ADRD risk in sub-groups that differ according to co-prevalent chronic HIV infection, NCD (specifically high blood pressure), as well as genetic risk such as APOE e4. ,1) To investigate how changes in the composition and metabolic capacity of the gut microbiota contribute to dysregulations in the metabolome of VD and impact ADRD, through an enhanced inflammatory response (systemic, intestinal and CNS). ,
Uganda 2025-10-17 19:32:06 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Apeta
ID: UNCST-2025-R021698
Historicising Gender Socialisation of Children In Lango Culture
REFNo: SS4515ES

I. To trace the evolution of gender roles, gender expectations, and social practices in Lango culture before the 19th century through to 2025.
II. To analyse how the evolution of children’s gender socialisation in Lango culture has influenced their gender identity.
III. To investigate the current perceptions of the Lango regarding traditional gender socialisation practices.
IV. To examine changes and continuity of gender-related cultural practices that foster or challenge gender equality among children.

Uganda 2025-10-17 19:28:23 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Beatrice Kimono Washi
ID: UNCST-2025-R016727
EXPLORING ADOLESCENT AUTONOMY IN HIV RESEARCH PARTICIPATION: PERCEPTIONS, BARRIERS, AND RECRUITMENT STRATEGIES IN KALUNGU DISTRICT.
REFNo: HS6504ES

Main Objectve:
To evaluate adolescents’ perceptions of autonomy in HIV research participation, identify the barriers that limit this autonomy, and assess research recruitment strategies used in Kalungu district.
specific objectives:
1. To assess adolescents’ perceptions of autonomy in making decisions about HIV research participation in Kalungu district.
2. To identify the barriers to adolescent autonomy during HIV research participation in Kalungu district.
3. To examine the strategies used to recruit adolescents into HIV research in Kalungu district.


Uganda 2025-10-17 19:26:25 2028-10-17 Medical and Health Sciences Degree Award
Mercy Wanyana Mugonola
ID: UNCST-2023-R006482
INNOVATIVE WORK BEHAVIOR AMONG ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS4389ES

Generally, the study seeks to explore strategies for enhancing innovative work behavior among academic staff in public universities. The study's major objective is to improve innovative work behaviors (IWB) by developing an IWB model that integrates the constructs of servant leadership, perceived organizational support, organizational culture, and employee empowerment from three different theories: social exchange, Denison's Organizational Culture Model, and Spritzer's empowerment theory. Specifically, eight objectives underpin this study namely: 1) to examine the relationship between servant leadership and IWB among academic staff of public universities, 2) to examine the correlation between perceived organization support and IWB of academic staff of public universities, 3) to assess the association between psychological empowerment and IWB among academic staff of public universities, 4) to examine the degree of association between servant leadership and psychological empowerment, 5) to determine the relationship between perceived organizational support and psychological empowerment among academic staff of public universities, 6) to examine the mediating influence of psychological empowerment in the relationship between servant leadership and IWB, 7) to examine the relationship between psychological empowerment and academic staff IWB and finally, 8) to assess how the relationship between perceived organizational support and IWB among staff of public universities is mediated by psychological empowerment.
Uganda 2025-10-17 19:24:25 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
LYDIACATRINA NAKIBWAMI
ID: UNCST-2024-R015974
Perceptions And Experiences Of Married People Regarding Socioeconomic Status And Marital Happiness In Kawempe Division
REFNo: SS4328ES

I. To explore married people’s understanding of marital happiness
II. To examine the lived experiences of married people regarding socioeconomic status and marital happiness.
III. To discover the perceptions of married people regarding socioeconomic status and marital happiness.

Uganda 2025-10-17 19:22:52 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Anthony  Batte
ID: UNCST-2022-R011127
Assessing Worldwide Acute Kidney Injury Epidemiology in Neonates( AWAKEN) 2.0 Study
REFNo: HS6568ES

Determine if AKI can predict chronic kidney disease, recurrent AKI and hypertension during early childhood,Determine if AKI is independently associated with mortality, length of stay, and discharge serum creatinine (SCr). ,Describe prevalence of AKI in a multi-national multi-center retrospective cohort, 5 years after the original AWAKEN study,
Uganda 2025-10-17 19:20:52 2028-10-17 Medical and Health Sciences Non-degree Award
Martin Mutambuka
ID: UNCST-2025-R020119
A comparative assessment of workload and resource utilization among Ugandan women associated with cooking of selected commercial beans
REFNo: A645ES

(1) To determine the Cooking Times of selected popular, commercial bean varieties (both Biofortified and non Biofortified) under a controlled laboratory environment. (2) To determine the Cooking Times and Costs of Resources used for selected commercial bean varieties under Household Field Kitchen environments (using firewood, charcoal and briquettes). (3) To determine how time saved from various activities translates into women’s ability to undertake additional productive ventures. (4) To determine Consumer Acceptability of selected Biofortified bean varieties by Rural and Urban consumers.
Uganda 2025-10-17 19:10:57 2028-10-17 Agricultural Sciences Non-Clinical Trial Non-degree Award
Dreck Ayebare
ID: UNCST-2025-R019088
Delivery and use of poultry vaccines in Uganda: A systems mapping and field-level study
REFNo: A655ES

Overall Aim To map and analyse the poultry vaccine supply system in Uganda, examining both upstream supply chain structures and downstream use behaviours, in order to identify institutional, logistical, and behavioural barriers to effective, equitable, and sustainable vaccine-based disease prevention. Specific Objectives Part A: Systems mapping 1. To map the structural and logistical flow of poultry vaccines in Uganda, from importation through distribution to the point of administration. 2. To examine institutional roles, interdependencies, and governance arrangements that influence vaccine regulation, quality control, and coordination. 3. To assess inequities in vaccine availability, cold chain access, pricing, and service delivery across geographic regions, institutional levels, and actor groups. 4. To co-develop stakeholder-informed recommendations for improving supply chain efficiency, regulatory coordination, and equitable vaccine access. Part B: Field-level practices 1. To identify the most used poultry vaccines and their sourcing patterns at the farm level. 2. To evaluate compliance with recommended vaccine handling and administration practices among farmers, veterinary workers, and agro vets. 3. To explore behavioural drivers—including knowledge, perceptions, motivations, and decision-making—that influence vaccine uptake and misuse. 4. To assess the role of agro-vet shop interactions, veterinary advice, packaging/labelling, and social norms in shaping field-level behaviours. To quantify key knowledge gaps, operational challenges, and access barriers that limit effective poultry vaccine use at the farm level.
Uganda 2025-10-17 19:09:27 2028-10-17 Agricultural Sciences Non-Clinical Trial Degree Award
Lydia Mwikali
ID: UNCST-2021-R012798
PERFLUOROALKYL SUBSTANCES IN SOURCE AND TREATED DRINKING WATER, AND THEIR REMOVAL USING CORNCOB-DERIVED BIOCHAR
REFNo: NS1042ES

vi. To elucidate the adsorption mechanisms of PFAS removal by corncob-derived biochar and MOFs, v. To determine the adsorption capabilities of the corncob biochar and MOFs for PFAS removal,iv. To prepare, synthesize and characterize corncob-derived biochar and MOFs for PFAS removal,iii. To estimate exposure and human health risk assessment of PFNA, PFHxS, PFOS and PFOA,ii. To determine spatial distribution of PFAS in water sources.,i. To determine the concentration of PFAS in source and treated drinking water,To determine the occurrence and human health risk assessment of PFAS in source and treated drinking water and evaluate the efficacy of corncob-derived biochar, and metal organic frameworks (MOFs) in PFAS removal.,
Kenya 2025-10-17 19:08:34 2028-10-17 Natural Sciences Non-Clinical Trial Degree Award
Judith Owokuhaisa
ID: UNCST-2022-R011528
ISOLATION AND CHARACTERIZATION OF BACTERIOPHAGES FROM WASTE WATER WITH BACTERICIDAL EFFECT ON ANTIBIOTIC RESISTANT ESKAPEE PATHOGENS IN SOUTH WESTERN UGANDA
REFNo: HS6636ES

1.) To determine the phenotypic and genotypic characteristics of bacteriophages isolated from surface and waste water in south western Uganda.
2.) To identify antibiotic resistance genes in bacteriophages and antibiotic resistant ESKAPEE pathogens.
3.) To assess the effect of isolated bacteriophages on antibiotic resistant ESKAPEE isolates.


Uganda 2025-10-17 19:07:48 2028-10-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
Determinants and Strategies for Childhood Immunization among Populations Facing Rural and Low-Income Vulnerabilities in Uganda
REFNo: HS6548ES

1.To identify the barriers to and facilitators of childhood routine immunization programs among populations facing low-income urban and rural vulnerabilities in Uganda; 2.To determine how the most significant facilitators and barriers to vaccination perceived by knowledge holders could be enhanced and mitigated, respectively; 3.To understand current vaccination strategies used to address barriers and to enhance facilitators for childhood vaccination programs; and 4.To highlight opportunities for enhancing current implementation strategies and map out priority areas based on knowledge holders’ perspectives.
Kenya 2025-10-17 19:06:55 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
HPV subtypes and pap smear findings among women screened for cervical cancer at Uganda Cancer Institute (UCI), Uganda
REFNo: HS3830ES

To determine the association between demographic characteristics, HPV positivity, and Pap smear findings among women seeking cervical cancer screening services in Uganda,4) To describe the findings from Pap smear among women seeking cervical cancer screening in Uganda,3) To determine the prevalence of HPV positivity among women living with HIV, seeking cervical cancer screening in Uganda,2) To determine the prevalence of HPV subtypes among women seeking cervical cancer screening in Uganda.,1) To describe the demographic characteristics of women seeking cervical cancer screening in Uganda,To determine the prevalence of HPV subtypes, and the association with demographic characteristics and Pap smear findings among women attending cervical cancer screening in Uganda.,
Uganda 2025-10-17 19:05:45 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MBABAZI GRACEMARY
ID: UNCST-2025-R017863
DYNAMIC CAPABILITIES AND FINANCIAL PERFORMANACE OF MICROFINANCE INSTITUTIONS IN UGANDA
REFNo: SS4124ES

1) To find out the relationship between dynamic capabilities and the financial performance of Tier 4 MFIs in Uganda.

2) To find out the relationship between dynamic capabilities and innovation among Tier 4 MFIs in Uganda

3) To establish the relationship between innovation and the financial performance of Tier 4 MFIs in Uganda.

4) To examine the mediating effect of innovation in the relationship between dynamic capabilities and the financial performance of Tier 4 MFIs in Uganda.

Uganda 2025-10-17 19:04:48 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
JOHNBOSCO NDINAWE
ID: UNCST-2025-R018067
QUALITY OF LIFE AND USE OF mHEALTH AMONG CANCER PATIENTS RECEIVING PALLIATIVE CARE IN WESTERN UGANDA
REFNo: HS6248ES

1.4 Research objectives: 1.4.1 Main Objective: To examine the quality of life (QOL), associated factors, and use of mHealth interventions among cancer patients receiving palliative care in Western Uganda. 1.4.2 Specific Objectives: 1) To examine the nature and use of mHealth interventions for PC for cancer patients in SSA based on the available literature. 2) To determine the level of QOL and associated factors among cancer patients under PC in Western Uganda. 3) To establish the effect of a text message-based intervention on the QOL of cancer patients receiving PC in Western Uganda.
Uganda 2025-10-17 19:03:25 2028-10-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda (WLLDC-SP)
REFNo: HS4371ES

To build an ecosystem for community engagement and training in suicide prevention in rural Uganda.,To evaluate the feasibility of an implementation strategy consisting of WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda,To co-design an implementation strategy manual for the WHO LIVE LIFE guide with the District Health Management Team as Champions for suicide prevention across the lifespan in rural Uganda. ,To co-design and evaluate the feasibility of a contextually tailored implementation strategy to identify and prepare members of the District Health Management Team (DHMT) as champions: the “WHO LIVE LIFE guide with DHMT as Champions for Suicide Prevention across the lifespan in rural Uganda,
Uganda 2025-10-17 18:59:00 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Ketola Tobias
ID: UNCST-2022-R009343
Establishing baselines in fauna diversity, phenology and abundance in key biodiversity hotspots across Uganda through collaborative research and capacity building
REFNo: NS889ES

Our project will sample birds and bats targeting biodiversity hotspots adjacent to and within
protected areas in Uganda. Through multiple visits across the next six years we plan to sample in
distinct biomes such as the North (Moroto, Kidepo valley, Agoro-agu, Morungole, Achwa)
Northeast (Pian Upe, Nakapiprit, Matheniko-Bokora), East (Mount Elgon, Loporokocho, Bukwo),
Northwest (Otzi forest, Ajai wildlife reserve, Luuku forest) southwest (Mgahinga, Bwindi and
around lake Victoria (Buvuma Island, Kalangala, Bugala). These regions are known to support
unique and often locally endemic species. In addition, many of these areas, such as the Kidepo and
the overall Karamoja regions, are notably understudied compared to regions in Western Uganda
Canada 2025-10-17 18:56:23 2028-10-17 Natural Sciences Non-Clinical Trial Non-degree Award
Hakim  Kalungi
ID: UNCST-2025-R018251
Process evaluation of the She Cares Program model in Uganda.
REFNo: HS6251ES

Study objective 1: Analyze change in FP services among adolescent girls and young women during the She Cares project period.
Study Objective 2: Examine how the She Cares outreach model and solutions were used by
adolescent clients and how clients experienced care with self-care promoters
Study Objective 3: Examine how the She Cares program model was implemented, its feasibility,
acceptability and potential scalability
Study Objective 4: Analyze the cost efficiency of the She Cares program model
Uganda 2025-10-17 18:50:38 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Balinandi Karabyo
ID: UNCST-2023-R007529
Evaluation of OraSure’s OraQuick Ebola Rapid Antigen Test using Sudan Ebolavirus in Preparation for Cadaveric Surveillance
REFNo: HS6258ES

1. To evaluate the performance characteristics (sensitivity, specificity, positive predictive value and negative predictive value of the OraQuick RDT for Sudan Virus detection using archived cadaveric oral swabs.
2. To determine the reliability of the OraQuick RDT in identifying true Sudan virus cases in a controlled laboratory setting before field implementation
Uganda 2025-10-17 18:48:41 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ASIIMWE EMILY
ID: UNCST-2025-R020015
THE ROLE OF MATERNAL EMPLOYMENT IN THE TEACHING AND LEARNING OF YOUNG LEARNERS IN EARLY CHILDHOOD EDUCATION CENTRES IN NANSANA MUNICIPALITY ,WAKISO DISTRICT, UGANDA
REFNo: SS4140ES

1.TO IDENTIFY THE IMPACT OF IMPACT OF MOTHERS' EMPLOYMENT ON CHILDREN'S ACADEMIC PERFORMANCE
2.TO FIND OUT STRATEGIES USED BY FAMILIES IN DEVELOPING THE ACADEMIC POTENTIALS OF THEIR CHILDREN
3.TO ANALYSE CHALLENGES FACED BY WORKING MOTHERS IN BALANCING THEIR DUTIES WITH CHILD CARE
Uganda 2025-10-17 18:46:52 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
LABE HOME-BASED EARLY CHILDHOOD EDUCATION EVALUATION PROJECT
REFNo: SS4168ES

a) What are the components and assumptions of the home based ECD model that make it work?
b) Does the model have correlational/cause outcomes on the community and children in terms of learning outcomes and retention in school?
c) How can LABE scale up with several adopters while maintaining the integrity of the model?

Uganda 2025-10-17 18:42:47 2028-10-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Prossie Nampijja
ID: UNCST-2025-R018736
COMMUNITY PARTICIPATION AND SUSTAINABILITY OF LOCAL GOVERNMENT PROJECTS IN UGANDA; A CASE OF MARKETS AND AGRICULTURAL TRADE IMPROVEMENT PROGRAMME (MATIP) IN LUGAZI MUNICIPALITY
REFNo: SS4427ES

i.To examine the level of community participation in planning on sustainability of local government projects in Lugazi Municipality. ii.To analyse the level of community participation in implementation on sustainability of local government projects in Lugazi Municipality. iii.To assess the significance of community participation in monitoring and evaluation on sustainability of local government projects in Lugazi Municipality.
Uganda 2025-10-17 18:33:25 2028-10-17 Social Science and Humanities Non-Clinical Trial Degree Award
Nathan Ntenkaire
ID: UNCST-2023-R008104
Knowledge and perceptions of local communities towards Guinea worm disease in Mubende district, Uganda
REFNo: HS6415ES

1. What is the extent of awareness and knowledge about Guinea worm disease among local communities in Mubende district? 2. Is there variation in knowledge levels across the different social demographics among local communities in Mubende district? 3. Have there been any reported or suspected cases of Guinea worm disease in the study area, and what evidence supports their occurrence? 4. What are the perception and experiences of local communities in Mubende district about Guinea worm disease? 5. What are the potential barriers that may threaten the sustained eradication of Guinea Worm Disease in Mubende District?
Uganda 2025-10-17 18:30:03 2028-10-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Akampurira Paul
ID: UNCST-2025-R017965
A DEEP LEARNING-BASED USER BEHAVIOR ANALYTICS MODEL FOR PROACTIVE CYBER THREAT DETECTION AND RISK MANAGEMENT AT NITA, UGANDA.
REFNo: SIR554ES

1.3 Major Objective
The major objective of this study is to develop user behavior analytics model based on deep learning that effectively detects anomalies and predicts cyber threats, enabling organizations to proactively perform risk management.
1.3.2 Specific Objectives
1. To establish requirements for designing a deep learning-based user behavior analytics model.
2. To design deep learning models (LSTM, GRU, ESN, and Transformers), tailored for user behavior analytics in cyber threat detection.
3. To evaluate and validate the model for user behavior analytics in cyber threat detection and insider risk management at NITA, Uganda.

Uganda 2025-10-17 17:51:49 2028-10-17 Engineering and Technology Non-Clinical Trial Degree Award
Joan Nakkazi
ID: UNCST-2025-R019521
Maternal Healthcare Service Utilization and Health-related Quality of Life among Young Pregnant Mothers 10-24years, in Eastern Uganda.
REFNo: HS6459ES

The main objective of the study is to evaluate the influence of maternal healthcare service utilization on health-related quality of life (HRQoL), and determine expectant mother factors associated with HRQoL among young pregnant mothers aged 10-24yrs in Eastern Uganda, so as to design strategies that strengthen identification of gaps and to develop an intervention and a MHCSU model to improve utilization of maternal healthcare services and improve HRQoL, for positive maternal and newborn health outcomes.i) To analyse the influence of uptake of ANC services on health-related quality of life among young pregnant mothers aged 10-24yrs in Eastern Uganda ii) To assess the effects of skilled birth attendance during delivery on health-related quality of life among young pregnant mothers aged 10-24yrs in Eastern Uganda iii) To examine the effects of access to postnatal care services on health-related quality of life among young pregnant mothers aged 10-24yrs in Eastern Uganda iv) To evaluate the mediating effect of expectant mother factors on maternal healthcare service utilization and health-related quality of life among young pregnant mothers aged 10-24yrs in Eastern Uganda
Uganda 2025-10-17 17:49:55 2028-10-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
CONFLICT-RELATED ATTACKS ON EDUCATION AND CHILDREN’S LOST LIFE OPPORTUNITIES (EDATTACK)
REFNo: SS4117ES

Study’s Primary objective
To systematically identify patterns of attacks on education (AoE) at the local level and analyze their consequences for individual children’s lost life opportunities.
Study’s Secondary objectives
1. To create a georeferenced dataset on AoE across sub-Saharan Africa, 2000–2025, using state-of-the art machine learning to analyze thousands of text sources
2. To develop innovative tools to model the spatio-temporal diffusion of AoE and similar conflict processes, readily available via GitHub
3. To determine the role played by international and national actors in mediating the consequences of AoE for childrenʼs life opportunities and understand how these dynamics are perceived by local stakeholders
4. To strengthen institutional collaboration with partners from the Global South and contribute to local research capacity building

Uganda 2025-10-17 17:48:05 2028-10-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Anyanzo Philip John
ID: UNCST-2024-R002208
CLASSROOM ASSESSMENT PRACTICES AND DEVELOPMENT OF SOCIAL STUDIES SKILLS IN UGANDA: A CASE OF SELECTED PRIMARY SCHOOLS IN WEST NILE REGION, UGANDA
REFNo: SS4406ES

study will be guided by the following objectives: •To identify the classroom assessment practices used by teachers to assess SST skills in primary schools in West Nile region. •To examine how classroom assessment practices contribute to the development of SST related skills among learners. •To assess the alignment between classroom assessment practices and national summative assessment criteria.
Uganda 2025-10-16 9:16:25 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Annet Nanvubya
ID: UNCST-2025-R015525
Assessing Knowledge, Attitudes and Practices on Ebola Virus Disease in Uganda
REFNo: SS4392ES

1. To determine levels of knowledge towards EVD among individuals living in Luwero and Nakasongola Districts.
2. To explore attitudes and practices towards EVD among individuals living in Luwero and Nakasongola Districts.
3. To create awareness through community sensitization and training on EVD in villages of Luwero and Nakasongola Districts where Ebola was previously diagnosed.

Uganda 2025-10-16 9:14:59 2028-10-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
MUGISA SAMUEL
ID: UNCST-2025-R020107
CAPACITY BUILDING, FIRM CAPABILITIES, GOVERNMENT REGULATIONS COMPLIANCE AND LOCAL CONTENT CONSUMPTION BY UGANDAN FIRMS IN THE OIL AND GAS SECTOR
REFNo: SS4398ES

Objectives The objectives of the study are: 1.To determine the relationship between capacity building and local content consumption of firms in Uganda’s oil and gas sector. 2. To examine the relationship between firm capabilities and local content consumption of firms in Uganda’s oil and gas sector. 3. To establish the moderating effect of government local content regulations compliance on the relationship between capacity building and local content consumption of firms in Uganda’s oil and gas sector. 4. To establish the moderating effect of government local content regulations compliance on the relationship between firm capabilities and local content consumption of firms in Uganda’s oil and gas sector.
Uganda 2025-10-16 9:13:18 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Community Engagement for Improved Ebola Disease Outbreak Prevention and Response in Uganda – Co-design for Future Global and Local Strategies
REFNo: HS6425ES

1.To identify success factors for early detection and response during previous outbreaks of EBD. (WP1)
2.To assess local knowledge of EBD among the community members in Uganda focusing on districts that previously experienced EBD outbreaks. (WP2)
3.To assess social, economic and cultural factors related to EBD-exposure at the wildlife-human interface. (WP2)
4.To co-design interventions for improved early detection and prevention of EBD using participatory and co-creational methods. (WP3)
5.To pilot and evaluate the implementation of the co-designed interventions in the local context. (WP4)


Uganda 2025-10-16 9:12:08 2028-10-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAFARI VIVIAN GORDON
ID: UNCST-2025-R017216
EFFECTIVENESS OF HARNESSING SURFACE RUNOFF WATER FOR SMALLSCALE IRRIGATION IN RUKIGA DISTRICT SOUTHWESTERN UGANDA
REFNo: A620ES

Establish the extent of harnessing surface runoff water for small scale irrigation and on farm activities in ana identified micro catchment in south western Uganda
Determine the costs for establishing a surface runoff water harvesting structure for small scale irrigation
Measure the quantity of surface runoff water collected in the water reservoir from the micro catchment to establish its availability through out the growing season for the selected crops
Establish the productivity of irrigated and non-irrigated crops produced under small scale irrigation during the dry spells and normal seasons
Uganda 2025-10-16 9:11:13 2028-10-16 Agricultural Sciences Non-Clinical Trial Degree Award
Charlotte Komuhangi
ID: UNCST-2025-R018038
A Phenomenological Study of Premarital Counselling Experiences and Challenges among Married Christians in Rubaga Division, Kampala, Uganda.
REFNo: SS4390ES

i. To explore the perceptions about premarital counseling among married Christians in Rubaga division.
ii. To examine the marital experiences of married Christians in Rubaga Division who have gone through premarital counseling.
iii. To analyse the opinion of married Christians in Rubaga Division on what can be done to improve premarital counseling

Uganda 2025-10-16 9:10:29 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Kambugu
ID: UNCST-2019-R000823
Evaluation of the Impact of the Epidemic Ready Primary Health Care Project on Outbreak Preparedness and Response in Primary Healthcare Facilities in Uganda.
REFNo: HS6147ES

To document challenges, best practices, and lessons learned during project implementation,To assess the rollout and the associated change in knowledge of healthcare workers trained using the clinical IDSR (cIDSR)digital training platform. ,To assess health facilities’ epidemic readiness using simulated patient exercises.,To assess the impact of the ERPHC longitudinal health worker capacity building mentorship on epidemic readiness: Surveillance, Infection Prevention and Control, and Case Management.,To evaluate the impact of the Epidemic Ready Primary Health Care project on outbreak preparedness and response in primary healthcare facilities in Uganda. ,
Uganda 2025-10-16 9:09:31 2028-10-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Erasmus Oreret Tukei
ID: UNCST-2024-R002444
PREVENTING ZOONOTIC DISEASE IN UGANDA’S GREAT APES (GORILLAS AND CHIMPANZEES): EVALUATING THE EFFICACY OF DISEASE PREVENTION TRAINING AND RESPONSIBLE TOURISM BEST PRACTICES
REFNo: NS1000ES

The overall objective is to evaluate the effectiveness of ranger trainings, informational tourist videos, and best practices in promoting responsible tourism and disease prevention at Kibale National Park (KNP; chimpanzees) and Bwindi Impenetrable National Park (BINP; gorillas). The research aims to assess changes in knowledge and behavior among rangers, tourists, and tour operators through surveys and behavioral assessments.,To assess the level of satisfaction among the tourist involved in Gorillas and Chimpanzee trekking in Bwindi Impenetrable National Park and Kibale National Park.,To assess knowledge and attitudes related to zoonotic disease risks and prevention best practices among tourists and rangers before and after the training sessions. ,
Uganda 2025-10-16 9:07:32 2028-10-16 Natural Sciences Non-Clinical Trial Degree Award
Justine Okello
ID: UNCST-2024-R005435
Determinants of Rift Valley Fever (RVF) Disease at The Human-Animal-Environment Interface in Lira and Apac Districts of Northern Uganda
REFNo: HS6654ES

To assess the capacity of the study districts to handle any outbreaks of Viral Heamorragic fevers including Rift Valley fever diseaseTo explore the Rift valley disease management in Lira and Apac Districts of Northern UgandaTo determine the sero-prevalence and associated risk factors of RVF disease among humans and domestic livestock at the human-animal and environment interface in Apac and Lira Districts of Northern Uganda
Uganda 2025-10-16 9:05:52 2028-10-16 Medical and Health Sciences Degree Award
KALINDA  PETER
ID: UNCST-2023-R007263
TIER FOUR MICROFINANCE SERVICES AND HOUSEHOLDS’ SOCIAL-ECONOMIC WELL-BEING OF SMALLHOLDER FARMERS IN SOUTHWESTERN UGANDA
REFNo: SS2332ES

4) To examine the mediating effect of financial literacy in the relationship between microfinance services and social-economic wellbeing of smallholder farmers in South Western Uganda.,3) To establish the relationship between financial literacy and social economic wellbeing of smallholder farmers in South Western Uganda.,2) To examine the relationship between microfinance services and financial literacy among smallholder farmers in South Western Uganda.,1) To examine the relationship between microfinance services and social-economic wellbeing of smallholder farmers in South Western Uganda.,The study is set out to examine the mechanism by which microfinance services are related to social-economic wellbeing among smallholder farmers in South Western Uganda. ,
Uganda 2025-10-16 9:02:54 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6666ES

To evaluate the efficacy of MK-8527 qm
compared to FTC/TDF qd for the
prevention of HIV-1 infection as assessed
by the incidence rate per year of adjudicated
HIV-1 infections.
Hypothesis: MK-8527 qm is superior to
FTC/TDF qd with respect to the hazard
ratio for HIV-1 infecti
Uganda 2025-10-16 17:51:09 2028-10-16 Medical and Health Sciences Clinical Trial Non-degree Award
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