Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 Uganda’s SafeStart+ EMTC Commodity Assessment
REFNo: HS6803ES

To assess the availability of essential health commodities across different levels of the health system, identifying areas of consistent supply, stockout patterns, and supply chain strengths or weaknesses.

ii) To evaluate the accessibility of health commodities by examining geographic coverage, service delivery points, and equity of access among different population groups, highlighting both successes and barriers.

 Uganda 2025-12-18 17:31:55 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rawlance  Ndejjo
ID: UNCST-2022-R010993
 MENTAL HEALTH POLICY IMPLEMENTATION IN UGANDA: INDICATORS, BARRIERS, AND ENABLERS
REFNo: HS6868ES

To document the barriers and enablers of mental health policy implementation and monitoring in Uganda.,To evaluate the feasibility of the proposed global-level mental health indicators for tracking policy implementation in Uganda and prioritize a contextual country list. ,To document current mental health data sources and examine their potential for tracking mental health policy implementation and monitoring.,To map mental health policies and indicators for their implementation in Uganda. ,To map mental health policy indicators, examine the potential of existing data sources to inform policy monitoring and implementation as well as explore needs, gaps and opportunities in policy implementation in Uganda providing a foundation for a comprehensive monitoring framework.,
 Uganda 2025-12-18 17:26:47 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
 Baseline Assessment of Basic Health Knowledge, Attitudes, Behaviours and Practices in Namanve Industrial Park and Surrounding community to Inform a Champion-Led Multimedia Health Education Intervention
REFNo: HS6818ES

1.3.1 General Objective To assess the baseline knowledge, attitudes, behaviours, and practices on basic health among workers and surrounding communities in Namanve Industrial Park and to use the findings to design a champion-led multimedia health education intervention. 1.3.2 Specific Objectives 1. To assess the current level of knowledge, attitudes, behaviors, and practices related to cervical cancer, first aid, nutrition, and WASH among workers and surrounding communities. 2. To identify barriers and facilitators influencing health-seeking behaviors and health information uptake among Namanve Industrial Park workers and surrounding communities. 3. To determine preferred communication channels and formats for health education among workers and surrounding communities. 4. To establish baseline indicators for evaluating the impact of the proposed health education intervention and informing the design of multimedia video content and training materials for the presentation champions
 Uganda 2025-12-18 17:20:35 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clara Kansiime
ID: UNCST-2020-R014325
 DECOLONISING ACCOUNTABILITY PRACTICES IN NGOS: INSIGHTS FROM UGANDA
REFNo: SS4671ES

1. To review existing debates on downward accountability within the Ugandan NGO sector, exploring how accountability practices are conceptualized and implemented. 2. To examine the perspectives of local NGO practitioners, beneficiaries, and relevant stakeholders on accountability in their contexts, capturing how these practices are experienced and understood on the ground. 3. To identify and document community practices, values, and participatory approaches that could inform culturally and contextually relevant accountability mechanisms in Ugandan NGO management. 4. To propose context-sensitive accountability pathways that challenge colonial legacies and promote sustainable, equitable, and community-owned development practices
Uganda 2025-12-18 17:12:50 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
KYOMUHENDO ROSARIA
ID: UNCST-2025-R022215
 DETERMINANTS OF TRACHOMA PREVENTION IN LOTISAN SUBCOUNTY, MOROTO DISTRICT
REFNo: HS6853ES

1. To assess the awareness of trachoma prevention practices among the people of Lotisan Subcounty, Moroto District.
2. To examine environmental factors influencing trachoma prevention practices in Lotisan subcounty
3. To determine the health-related factors associated with trachoma prevention.

 Uganda 2025-12-18 16:48:56 2028-12-18 Medical and Health Sciences Non-Clinical Trial Degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
 KNOWLEDGE PRODUCTION PRACTICES AND COMMUNITY ENGAGEMENT OUTCOMES: A CASE OF SELECTED UNIVERSITIES IN CENTRAL UGANDA
REFNo: SS4134ES

a) To analyze the influence of research activities on community engagement outcomes of selected universities in central Uganda
b) To examine the effect of teaching on community engagement outcomes in selected universities in Central Uganda
c) To evaluate the mediating role of knowledge translation mechanisms on knowledge production practices and community engagement outcome
 Uganda 2025-12-10 20:31:20 2028-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 Assessing Local Needs and Potential Usability of Machine Learning-Based TBI Care Tools in Uganda: A Qualitative Improvement Initiative
REFNo: HS6782ES

To assess whether the current application meets the participants\' identified needs. ,To evaluate the effectiveness and usability of the proposed mobile application by gathering feedback from healthcare professionals after hands-on experience.,To identify current challenges and areas for improvement in TBI management from the perspectives of Ugandan healthcare professionals.,To identify current challenges in TBI management and assess the effectiveness, usability, and alignment of a proposed mobile application with the needs of Ugandan healthcare professionals,
 Uganda 2025-12-10 20:23:51 2028-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Banturaki
ID: UNCST-2024-R015929
 EFFECT OF THE COMMUNITY-BASED HEALTH EDUCATION INTERVENTION ON PERCEPTIONS AND SHOW-UP FOR AMBULATORY SURGERY AMONGST PATIENTS AT KYABIRWA SURGICAL CENTER, BUDONDO SUB COUNTY, JINJA CITY
REFNo: HS6619ES

1. To determine the proportion of patients who positively perceive ambulatory surgery, following reception of community-based education or non-reception of it.
2. To determine the proportion of patients who show up for surgery at Kyabirwa surgical center, following reception of community-based education or non-reception of it.
3. To evaluate the effect of the community-based health education intervention on perceptions towards ambulatory surgery at Kyabirwa surgical center, Budondo sub county, Jinja city.
4. To analyze the effect of the community-based health education intervention on show-up for ambulatory surgery at Kyabirwa surgical center, Budondo sub county, Jinja city.
 Uganda 2025-12-10 20:20:52 2028-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eunice Muyama
ID: UNCST-2024-R015299
 Evidence based strategies to enhance adaptation to climate variability and change among smallholder farmers in Mbale District
REFNo: SS4544ES

Determine patterns of rainfall and temperature to establish the incidence of climate variability and change in Mbale district. Establish the effects of rainfall and temperature patterns on smallholder farmers in Mbale district. Identify the adaptation strategies used by smallholder farmers in Mbale district. Evaluate the challenges faced by smallholder farmers in implementing these adaptation strategies in Mbale district.
Uganda 2025-12-10 20:15:43 2028-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
Akankwatsa Dickson
ID: UNCST-2025-R020428
 ASSESSING CAPACITIES OF BORDER PROXIMAL HEALTH FACILITIES TO TACKLE EPIDEMIC PRONE DISEASES: A CASE STUDY OF THE WEST NILE REGION OF UGANDA
REFNo: HS6771ES

1. To assess the preparedness and response capacities of border proximal health facilities to manage ill travellers suspected of epidemic prone diseases along the West Nile region, Uganda. 2. To establish the challenges faced by boarder health facilities along the West Nile region of Uganda, in detection and management of ill travellers suspected of epidemic prone diseases
Uganda 2025-12-10 20:11:42 2028-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ASINGWIRE JENINAH FLAVIA
ID: UNCST-2024-R003589
 Perceived Psychosocial Classroom Learning Environment, Academic Interest and Academic Achievement in Mathematics among students in Secondary Schools in Greater Mbarara Region
REFNo: SS4695ES

1. To evaluate the influence of changes in the perceived classroom learning environment on academic achievement in mathematics among secondary school students in Greater Mbarara.
2. To examine the relationship between changes in the perceived classroom learning environment and changes in academic interest in mathematics among secondary school students in Greater Mbarara.
3. To assess whether change in academic interest mediates the relationship between changes in the perceived classroom environment and change in academic achievement in mathematics among secondary school student in greater Mbarara.
4. To compare changes in academic interest and changes in academic achievement in mathematics between groups of students categorized by their perceived classroom learning environment quality

Uganda 2025-12-10 20:07:48 2028-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
INNOCENT BWENGYE
ID: UNCST-2025-R019226
 OPTIMIZATION OF FEW-SHOT LEARNING MODELS FOR CLASSIFICATION AND RANKING OF BIOMATERIALS FOR BONE TISSUE ENGINEERING
REFNo: SIR592ES

The general objective of this study is to improve the process of selecting biomaterials for bone tissue engineering by developing a few-shot learning model that leverages Bayesian optimization to identify optimal hyperparameters, addressing data scarcity challenges and enhancing model accuracy, generalizability, and computational efficiency.

SPECIFIC OBJECTIVES
I. To critically evaluate existing few-shot learning techniques, analyzing their architectures, strengths, and limitations, with a specific focus on their applicability to biomaterial classification and ranking in bone tissue engineering.
ii.To design and implement a Bayesian-optimized few-shot learning model that effectively learns from limited data and provides robust uncertainty quantification in predictions for BTE applications.
iii.To integrate transfer learning techniques into the Bayesian-optimized few-shot learning framework to enhance its performance and adaptability to biomaterial datasets with diverse mechanical properties.
iv.To evaluate the performance of the proposed model on classification and ranking tasks specific to bone tissue engineering

 Uganda 2025-12-10 19:58:41 2028-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Empowering Women for Better Reproductive Health Outcomes (EMPOWER): Monitoring, Evaluation, Research and Learning
REFNo: SS4684ES

4. To generate rapid operational research and learning agenda.,3. To assess the quality and completeness of programme data by conducting periodic data quality assessments (DQA) and verifying the accuracy and attribution of results reported,2. To determine baseline values for key RMNCAH service coverage, quality-of-care, and health system indicators across participating facilities, providers, and client populations.,1. To validate EMPOWER’s Theory of Change, Results Framework and Logframe to ensure that indicators, assumptions, and data sources are appropriate, measurable, and aligned with national RMNCAH priorities.,The purpose of this study is to monitor, evaluate, and generate evidence on the design, implementation, and outcomes of the EMPOWER programme in order to strengthen accountability and inform adaptive management to improve RMNCAH outcomes in Uganda.,
 Uganda 2025-12-08 12:54:10 2028-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
 High-Performance, Multivariate, Accessible Tools for Early HMB Identification and Iron Deficiency Risk Prediction (VITAL-HMB)
REFNo: HS6715ES

1. to develop and validate biomarkers and risk factors that accurately identify women at risk of heavy HMB and iron deficiency complications, thereby enabling earlier diagnosis, targeted intervention and improved health outcomes for HMB affected women across diverse healthcare settings.
 Uganda 2025-12-08 12:43:39 2028-12-08 Medical and Health Sciences Non-degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
 Investment in Research and National Development in Uganda: A Case of projects in the Science Granting Councils Initiative
REFNo: SS4681ES

1. To Classify Uganda's research by field and type and examine the contribution of research indicators such as employment, innovation and knowledge development
2. To Estimate Return on Investment of Research by type in scientific field as well as national level
3. Predict Return on Investment for a given range of investment amounts over 5, 10 and 15 year periods
 Uganda 2025-12-05 19:24:37 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Barriers to effective utilization of vaccines and immunization services In Uganda- A qualitative Assessment
REFNo: HS6784ES

a) To explore socio-demographic characteristics affecting access to immunization services in Uganda.
b) To explore health facility characteristics affecting access to immunization services in Uganda.
c) To explore geographical and community level characteristics affecting access to immunization services in Uganda.
d) To explore and identify policy gaps affecting access to immunization services in Uganda.

 Uganda 2025-12-05 19:19:05 2028-12-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Developing and refining REConneCteD: a digitally integrated post-discharge care intervention for children in East Africa
REFNo: HS6806ES

Iteratively test and refine the integrated post-discharge care intervention and associated implementation resources through usability assessments and pilot testing,Build the necessary technical components and implementation resources (such as training materials and counseling guides) to enable functionally effective integration of the intervention within both facility and community settings,Develop the community-based post-discharge bundle of interventions, including workflows, care delivery materials, and associated training material, Develop the facility-based post-discharge bundle of interventions, including workflows, care delivery materials, and associated training material,The main objective of this formative research phase is to develop and refine a comprehensive, integrated post-discharge bundle of interventions for high-risk children that spans both facility and community settings,
 Uganda 2025-12-05 19:15:17 2028-12-05 Medical and Health Sciences Non-degree Award
AMPAIRE WYCLIFFE
ID: UNCST-2025-R017187
 SOURCE APPORTIONMENT AND BIODEGRADATION OF PAHs AND PFAS FROM WATER AND SEDIMENTS ALONG L. ALBERT
REFNo: NS1070ES

i. To determine the concentrations of 25 selected PAHs and 18 PFAS in water and sediment samples from Lake Albert using GC-MS/MS and LC-MS/MS, respectively.
ii. To identify the potential sources and spatial distribution patterns of PAHs and PFAS in Lake Albert using principal component analysis (PCA), HCA multivariate statistical techniques, and a fugacity-based model.
iii. To evaluate the human and ecological health risks posed by combined PAH and PFAS contamination in Lake Albert, using the US EPA Exposure Factors Handbook for risk characterization.
iv. To come up with potential biodegradation pathways for one selected PAH and one selected PFAS compound identified in water and sediment samples.

 Uganda 2025-12-05 19:12:24 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
JESSE LIMO MWANGA
ID: UNCST-2025-R019331
 Development of a web-based project management application to enhance construction project performance
REFNo: SS4618ES

I. To determine the gaps in existing project management applications based on stakeholder requirements. II. To design a prototype web-based project management application that addresses the gaps in existing applications based on stakeholder requirements. III. To assess the effectiveness of the prototype web-based project management application in addressing the gaps in existing applications and enhancing construction project performance in Uganda.
Uganda 2025-12-05 19:08:11 2028-12-05 Social Science and Humanities Non-Clinical Trial Degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
 Prescribing and dispensing practices of antimicrobials and drivers for inappropriate use among staff in licensed private retail pharmacies in Kampala and Mbarara cities, Uganda
REFNo: HS6581ES

o explore drivers of inappropriate use of antimicrobials in licensed private retail community pharmacies in Kampala and Mbarara cities,To assess antimicrobial prescribing and dispensing practices among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To determine the level of knowledge and perceptions on antimicrobial resistance among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To assess antimicrobial prescribing and dispensing practices and drivers of inappropriate use among staff in selected licensed private retail community pharmacies in Kampala and Mbarara cities in Uganda so as to add on the available evidence for fostering antibiotic stewardship in private pharmacies.,
 Uganda 2025-12-05 18:44:34 2028-12-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Wamono
ID: UNCST-2025-R017178
 Impact of anthropogenic stressors on ecosystem health and potential in-stream restoration measures of river Manafwa catchment in eastern Uganda
REFNo: NS993ES

I.Examine the influence of anthropogenic stressors on Physico-chemical water quality parameters in river Manafwa catchment in eastern Uganda. II.Analyse the influence of anthropogenic stressors on the macroinvertebrate assemblages in river Manafwa catchment in eastern Uganda. III.Asses the community perception on how their activities affect aquatic ecosystem health in river Manafwa catchment in eastern Uganda. IV.Establish and asses the performance of selected restoration measures in enhancing river ecosystem health in river Manafwa catchment in eastern Uganda.
Uganda 2025-12-05 18:39:17 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
Emmanuel  Luyirika BK
ID: UNCST-2025-R021521
 Destigmatizing Breast Cancer: Village Health Teams Using a Video Education Tool
REFNo: SS4394ES

1)Improve knowledge about breast cancer among VHTs 2)Evaluate if community members found this video tool to be an acceptable and helpful way to learn more about breast cancer. 3)Evaluate if VHTs found this video tool to be an acceptable and helpful way to share information about breast cancer.
Uganda 2025-12-05 18:37:27 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening (SIMCS)- A Cluster Randomized Trial
REFNo: HS6567ES

(ii) To evaluate the impact of the SCD SIMCS on access to screening and care and outcomes of children with SCD,
 Uganda 2025-12-05 18:30:02 2028-12-05 Medical and Health Sciences Clinical Trial Non-degree Award
Julius Ssendiwala
ID:
EVALUATION OF HIV INTEGRATION INTO ROUTINE CARE AT HEALTH FACILITIES IN UGANDA: LESSONS LEARNT FROM -THE COVID-19 HIV SERVICE DELIVERY ADAPTATIONS AND THE US PRESIDENT EXECUTIVE ORDERS
REFNo: HS6720ES

1. To document the health system adaptations that occurred during the COVID-19 pandemic, and the recent US President Executive Orders and how are they are being utilized for current HIV integration efforts?
2. To document the various models of HIV integration currently being implemented, and the factors that facilitate or hinder their successful implementation
3. To assess the uptake, feasibility, and acceptability of integrating HIV services into routine healthcare services

 Uganda 2025-12-03 18:46:20 2028-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 VALIDATION OF AN OFFLINE DEEP – LEARNING AI MODEL FOR ESTIMATING FVC AND FEV₁ FROM CHEST X‑RAYS IN A RESOURCE‑LIMITED UGANDAN CLINICAL SETTING.
REFNo: HS6703ES

Primary Objective
To evaluate the accuracy of an offline, deep-learning AI model in estimating forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁) by comparing AI-predicted values against spirometry-measured values.

Secondary Objective
To determine the agreement between AI-derived and spirometry-derived FEV₁/FVC ratios, and assess its utility for identifying airflow obstruction (i.e., FEV₁/FVC < 0.70).
 Uganda 2025-12-01 22:01:17 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 Exploring Factors Influencing COVID-19 Vaccination Uptake: A Qualitative Study in Uganda
REFNo: SS4582ES

To explore the factors and contextual differences that influenced COVID-19 vaccination uptake in Uganda, to compare these with experiences in Burundi and Rwanda, and to identify key predictors and opportunities for regional learning
 Kenya 2025-12-01 21:44:17 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
STELLA NABIRYE
ID: UNCST-2024-R003637
 Evaluation of outcomes of anticoagulation and factors associated with Time in Therapeutic Range among Rheumatic heart disease patients on vitamin K antagonists attending care at the Uganda Heart institute
REFNo: HS6728ES

General objective
To evaluate the outcomes of anticoagulation and factors associated with time in therapeutic range among Rheumatic heart disease patients on vitamin K antagonist attending care at Uganda Heart Institute

specific objectives
1.To determine the clinical outcomes of anticoagulation among Rheumatic heart disease patients on vitamin K antagonists attending care at Uganda Heart Institute

2.To determine the factors associated with time in therapeutic range among Rheumatic disease patients on vitamin K antagonists attending care at Uganda Heart Institute

3.To explore patients’ attitudes and knowledge on the use of vitamin K antagonists among Rheumatic heart disease patients attending care at Uganda Heart Institute

4.To explore clinicians’ perception of the use of vitamin K antagonists in managing patients with Rheumatic heart disease attending care at Uganda Heart Institute
 Uganda 2025-12-01 21:35:22 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
 Improving the quality of face sheet completion at Mulago National Referral Hospital
REFNo: HS6627ES

1. To determine the proportion of face sheet that are not complete at Mulago National Referral Hospital. 2. To identify the factors that contribute to failure of doctors to complete face sheet at Mulago National Referral Hospital. 3. To identify the measures that can be put forward towards completion of face sheet at Mulago National Referral Hospital.
Uganda 2025-12-01 21:28:40 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mirembe SarahAngella
ID: UNCST-2025-R021000
 Influence of Women's Participation In The Rice Value Chain on Household Dietary Diversity in Eastern Uganda
REFNo: SS4586ES

1. To examine the extent of women’s participation in the rice production, processing, and marketing activities within selected rice-oriented households in Namasagali sub-county, Eastern Uganda. 2. To identify the institutional factors that influence women’s participation as rice value chain actors at the household level. 3. To assess the dietary diversity of rice-oriented households in Namasagali sub-county, Eastern Uganda. 4. To establish a relationship between women’s participation and household dietary diversity.
 Uganda 2025-12-01 21:16:33 2028-12-01 Social Science and Humanities Degree Award
Nambusi Kyegombe Davina Ndibalekera
ID: UNCST-2022-R009559
 Ethics in Action in Low and Middle-Income Settings (EALMIC) Study: Challenges faced by researchers in applying ethical principles in Uganda
REFNo: SS4624ES

This aim of this study is to explore the emotional and psychological challenges faced by health researchers in Uganda working with vulnerable populations and on sensitive topics, in order to inform ethical guidelines and support strategies for enhancing researchers' well-being.
The study will be guided by five main objectives:
1. To explore researchers’ experiences of conducting research with vulnerable populations and on sensitive topics.
2. To explore how researchers’ experiences affect their wellbeing.
3. To identify coping and support mechanisms used by researchers to respond to their experiences.
4. To assess the ethical challenges faced when working with vulnerable populations.
5. To explore researchers’ perceptions of the role of cultural factors, including ubuntu principles, patriarchal gender norms, respect for elders and social hierarchies, on researchers’ experiences.

 Uganda 2025-12-01 21:13:31 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Atwebembeire John Mushomi
ID: UNCST-2025-R022006
 Evaluation of the ASRH Gatherings for Young Mother Gardeners Program
REFNo: SS4584ES

To assess the short- and medium-term impacts of the ASRH Gatherings and integrated livelihood support on young mothers in Kasese District.1. i. Examine how the program addresses challenges faced by adolescent mothers. 2. ii. Document transformative changes in participants’ lives, including aspirations, health, and livelihoods. 3. iii. Provide evidence-based recommendations for strengthening and scaling the program.
 Uganda 2025-12-01 21:05:46 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
 Rheumatic Heart Disease among Pregnant women in Northern Uganda: Prevalence, Impact on Pregnancy Outcomes and Strategy for Early Identification.
REFNo: HS6717ES

General Objectives
To determine the prevalence of RHD in pregnancy in Northern Uganda, the maternal and fetal outcomes and use this data to develop and validate clinical risk scores that predict presence of RHD in pregnancy and those at increased risk for adverse maternal outcomes.
Specific Objectives
Objective 1
A. To determine the prevalence of RHD among pregnant women in a community setting in Northern Uganda.
B. To design a diagnostic risk score that predicts presence of RHD in early pregnancy in Northern Uganda
Objective 2
A. To determine the maternal, and fetal outcomes of pregnant women with RHD in a community setting in Northern Uganda.

Uganda 2025-12-01 20:59:51 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Cromwell Okello
ID: UNCST-2025-R021939
 Rethinking the Potential of Formal Education in Buttressing the Peace–Economic Development Nexus among Karamojong Pastoralists in Moroto District, Uganda.
REFNo: SS4615ES

The study aims to critically examine the interconnections between formal education, peacebuilding, and economic development among the Karamojong pastoralist communities in Moroto District, Northeastern Uganda. Specifically, it seeks to understand how formal education can be strategically leveraged to promote social cohesion, gender equity, and sustainable livelihoods, while interrogating the socio-cultural, political, and economic dynamics that influence its implementation and outcomes.
Anchored in Pierre Bourdieu’s Theory of Practice, the study explores how education operates as both a field of social reproduction and a potential catalyst for transformation within a historically marginalised pastoralist society.
Research Objectives:
To realise the overarching aims of the study, the following research objectives have been framed:
1. To explore how Karamojong pastoralists experience and perceive access to formal education across different levels (primary, secondary, tertiary, and vocational), focusing on the social, cultural, economic, and geographical factors that shape participation and exclusion.
2. To examine the extent to which formal education, in its current form and cultural relevance, contributes to conflict mitigation, peacebuilding, social cohesion, and economic resilience among Karamojong pastoralists.
3. To analyse how the socio-cultural, political, and economic characteristics of the Karamojong people influence the formulation and implementation of educational policies and strategies within their region.
4. To investigate how formal education shapes gender relations, power dynamics, and opportunities for both women and men in the Karamojong community, particularly in relation to peacebuilding and economic development.
5. To co-develop culturally relevant educational strategies and curriculum innovations that integrate indigenous knowledge and support peacebuilding, gender equity, and sustainable development in pastoralist contexts.
6. To formulate evidence-based policy recommendations that align educational policies and practices with the socio-cultural realities, aspirations, and economic needs of the Karamojong pastoralist communities.
 Uganda 2025-12-01 20:53:21 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Assessing Willingness to Pay (WTP) for Family Planning Products in Uganda: Insights into consumer demand and affordability
REFNo: HS6749ES

Study Aim:
The overall aim of this study is to assess and understand the factors influencing willingness to pay for the different FP products in the Ugandan Market and barriers to WTP for the contraceptive’s products from all key stakeholders in the current market. Development of the study aims was guided by a series of consultative meetings with key stakeholders including program implementers and review of the recent literature on WTP studies. The study generates evidence to fill key gaps identified from the previous studies conducted on WTP focusing on the underlying factors to client WTP for FP products and services.
1.4 Specific Objectives:
1. To assess the current willingness to pay for Family Planning products among different population segments in Uganda.
2. To identify socio economic and demographic factors influencing willingness to pay for contraceptives
3. To integrate findings from previous WTP studies to provide a comprehensive -analysis and holistic understanding of pricing dynamics.
4. To identify key factors influencing pricing decisions, including cost-to-delivery and market affordability.

 Uganda 2025-12-01 20:44:08 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Akampurira
ID: UNCST-2025-R019367
 Stakeholder Engagement, Entrepreneurship Education, and Entrepreneurial Intention among Business Graduates of Chartered Universities in Southwestern Uganda
REFNo: SS4425ES

1. To determine the relationship between stakeholder engagement and entrepreneurial intention among university business graduates. 2. To assess the relationship between stakeholder engagement and entrepreneurship education among university business graduates. 3. To evaluate the relationship between entrepreneurship education and the entrepreneurial intention of university business graduates. 4. To analyse the mediating role of entrepreneurship education on the relationship between stakeholder engagement and entrepreneurial intention among university business graduates.
Uganda 2025-12-01 20:37:44 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Nasal Microbiome, Inflammatory Markers, and Infectious Agents among individuals with Biomass Fuel COPD in Uganda ACRONYM: ASCENT–NASAL Study
REFNo: HS6748ES

Aim 1: Characterize the nasal microbiome composition among individuals with and without COPD who
have different levels of air pollution exposure.

Aim 2: Assess nasal inflammatory marker differences among individuals with and without COPD who
are exposed to different levels of air pollution.

Aim 3: Determine the prevalence of viral and bacterial respiratory pathogens among individuals with
and without COPD and their association with PM2.5 exposure.
 Uganda 2025-12-01 14:33:20 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Safety, preliminary efficacy, and Pharmacokinetics of Herbal/Natural/ Traditional therapeutic products for the management of Diabetes Mellitus in Uganda.
REFNo: HS6530ES

Main Objective
1. To evaluate the safety, effectiveness and pharmacokinetics of 3 selected NDA- notified herbal/natural/traditional therapeutic products in Uganda, designated IMP1, IMP2, and IMP3.
2. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of natural therapeutics in Uganda.

Specific Objectives
1. To determine the efficacy of selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the treatment of diabetes mellitus in adult patients in Uganda
2. 2. To assess the effect of the selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) on specific cardio-metabolic characteristics of adult patients with DM in Uganda.
3. To assess clinical and laboratory adverse events associated with selected NDA- notified herbal/natural/traditional therapeutic products, specifically IMP1, IMP2 and IMP3 in adult patients with DM in Uganda.
4. To investigate the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.
5. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of herbal/natural/traditional therapeutics in Uganda.e the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.

Uganda 2025-12-01 14:19:22 2028-12-01 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Matovu Wasswa
ID: UNCST-2025-R021145
 Understanding Power, Institutions, and Policy Dynamics: A Political Economy Analysis of Youth Employment in Uganda
REFNo: SS4607ES

Research Questions The political economy analysis aims to answer two overarching research questions: I. How can current policies and regulatory frameworks be activated and enhanced to provide dignified and fulfilling work opportunities for youth in Uganda? II. What industrial and trade policies and/or plans will enable Uganda to leverage its demographic transition, the 4th industrial revolution, and the evolving digital economy to create adequate opportunities for dignified and fulfilling work for Ugandan youth? Purpose and Objectives The main purpose of this study is to examine how political, institutional, and economic structures interact to shape youth employment outcomes in Uganda. Specifically, the research seeks to: • Map the formal and informal policy, regulatory, and institutional frameworks governing youth employment. • Analyse the interests, incentives, and power dynamics of key actors who influence or obstruct youth employment reforms. • Understand the lived experiences, perceptions, and aspirations of young people in relation to work, inclusion, and voice. • Identify enablers and constraints to the implementation of effective and inclusive employment strategies. • Generate context-sensitive, actionable recommendations for policy and institutional reform.
Uganda 2025-11-26 14:32:03 2028-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sarah Wilker
ID: UNCST-2025-R019791
 One size fits all? Towards individual prediction of treatment success for posttraumatic stress disorder in post-conflict settings (TRAUMA-FIT)
REFNo: HS6712ES

Main Objective 1. to identify individual predictors of treatment response to two different treatments in survivors with PTSD in a post-conflict setting Specific Objectives 1. Investigate whether NET is, on average, more effective than PM+ for the treatment of PTSD 2. Identify predictors of optimal response in the two conditions, and thereby identify predictors of treatment success in a trauma-focused versus present-focused treatment 3. Investigate the explanatory role of socio-ecological factors in PTSD treatment response
 Germany 2025-11-26 14:28:24 2028-11-26 Medical and Health Sciences Clinical Trial Degree Award
Pamela Atim
ID: UNCST-2020-R014964
 Effects of biomass fuel usage on indoor air quality and associated respiratory health of women and children in Northern Uganda
REFNo: HS6606ES

1.To analyse the trends of biomass fuel usage in Uganda from 2001 to 2022. 2.To determine the factors associated with respiratory symptoms among women and children in rural and urban areas of Northern Uganda. 3.To quantify the levels of personal exposure of women to air particles (PM2.5, PM10) in the different micro-environments. 4.To explore the perspectives of the community and stakeholders regarding the impacts of cooking fuels.
Uganda 2025-11-26 14:26:18 2028-11-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Muzaale tonny
ID: UNCST-2023-R005970
 THE CONTRIBUTION OF ALTERNATIVE ASSESSMENT APPROACHES IN ENHANCING THE ASSOCIATION BETWEEN TEACHING AND LEARNING: THE CASE OF SELECTED PUBLIC UNIVERSITIES IN CENTRAL UGANDA. -
REFNo: SS4469ES

i. To establish the relationship between lecture-based instruction and learning in Public Universities in Central Uganda
ii. To establish the relationship between student centered learning and learning in Public Universities in Central Uganda
iii. To establish the relationship between technology based instruction and learning in Public Universities in Central Uganda
iv. To assess the extent to which alternative assessment moderates the association between dynamics of teaching and learning in selected higher institutions of learning
v. To assess the extent to which effective assessment policy implementation moderates the association between teaching and learning in selected higher institutions of learning

Uganda 2025-11-26 14:24:34 2028-11-26 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Gobo
ID: UNCST-2025-R018025
 Factors Influencing Adoption of Renewable Energy Interventions: A case of Refugees and Host Communities in Terego District Northern Uganda
REFNo: SS4489ES

1) To determine attitudes towards renewable energy interventions among refugees and the host communities in Terego District. 2) To examine the relevance of renewable energy interventions to refugees and the host communities in Terego District. 3) To determine the effectiveness of renewable energy interventions to refugees and the host communities in Terego District.
Uganda 2025-11-26 14:21:52 2028-11-26 Social Science and Humanities Degree Award
PAUL OPIO
ID: UNCST-2025-R019548
 EFFECT OF SPORTS PARTICIPATION ON RETENTION AND ACADEMIC ACHIEVEMENT OF PRIMARY SCHOOL GOING CHILDREN IN KARAMOJA REGION OF UGANDA
REFNo: NS1008ES

To investigate the effect of Sports Participation on retention of Primary School children in Karamoja Region of Uganda.
To examine the effect of Sports Participation on literacy and numeracy of Primary School children in Karamoja Region of Uganda.
To explore the relationship between Sports participation and completion rates of Primary School children in Karamoja Region of Uganda.
To assess the effect of Sports Participation on regular school attendance of Primary School children in Karamoja Region of Uganda.
 Uganda 2025-11-26 14:02:49 2028-11-26 Natural Sciences Non-Clinical Trial Degree Award
Julius Tabi Izza
ID: UNCST-2022-R009052
 A Theological Reappraisal of Bride Wealth: The Practice of Oku Jeza among Lugbara Christians in the Diocese of Ma'di-West Nile
REFNo: SS4590ES

The study will seek to analyze the challenges of oku jeza, a practice among Lugbara Christian community in the Diocese of Ma’di-West Nile on church marriage and frame theological approach to revisit the practice while maintaining its intended role.
Uganda 2025-11-21 15:07:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Zaina Nabirye Lubwama
ID: UNCST-2025-R022146
 The Persistance of Indian Built Heritage in Busoga, Eastern Uganda, 1903-2023.
REFNo: SS4509ES

1. To examine the evolution of Indian-built heritage in Busoga from 1903 to 1962.
2. To analyze how and why Indian-built heritage adapted and maintained its vitality from 1962 to 1979.
3. To examine the changes and continuities of Indian built heritage in Busoga from 1979 to 2023.

 Uganda 2025-11-21 14:58:05 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Sofia Fernandez
ID: UNCST-2025-R019676
 Investigating the lack of male involvement in community based agricultural education programs in Kamuli, Uganda
REFNo: SS4581ES

1. Examine the man's perception of their role in family nutrition and agriculture.
2. Identify the social and cultural barriers to involvement for men.
3. Collect ideas for solutions that could increase male participation.
 USA 2025-11-21 14:52:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ahimbisibwe
ID: UNCST-2025-R018434
 Co-ethnic Peers in Higher Education. Surname-ethnicity connection and validation exercise
REFNo: SS4575ES

1. This project will evaluate the effectiveness of using surname-based machine learning models in predicting identity with a focus on ethnic peer effects.

2. Also, we will evaluate how High-ability and co-ethnic peer networks may shape career opportunities and national identity and pride
 Uganda 2025-11-21 14:50:09 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Micheal Ivan Lyazi Micheal Ivan
ID: UNCST-2025-R021640
 An Assessment of Gender Integration in Equity Accelerator Fund (EAF) Implementation in Uganda
REFNo: SS4547ES

1. 1. To describe the specific gender-related barriers to immunization access among Uganda’s zero-dose population archetypes. 2. 2. To assess the implementation of EAF gender integration strategies. 3. 3. To identify gaps in the implementation of EAF gender integration strategies. 4. 4. To explorer how gender integration influences the number of ZD/ under immunized cases across the different population architypes in the study Geographies.
 Uganda 2025-11-21 14:44:56 2028-11-21 Social Science and Humanities Non-degree Award
MALLON TUSUUBIRA
ID: UNCST-2025-R021850
 SURVEY ON PARATUBERCULOSIS IN SLAUGHTERED GOATS AT KAMPALA CITY ABATTIOR
REFNo: A654ES

General objective
To establish the prevalence of Mycobacterium avium subsp. paratuberculosis infection in goats
Specific Objectives
i. To determine the prevalence of the gross and microscopic lesions associated with paratuberculosis in the ileocecal junction and associated lymph nodes of goats slaughtered at Kampala city abattoir
ii. To establish the prevalence of Mycobacterium avium sub species paratuberculosis in suspected cases using polymerase chain reaction (PCR)

 Uganda 2025-11-21 14:36:09 2028-11-21 Agricultural Sciences Clinical Trial Degree Award
Martin Origa Jobson Ariel
ID: UNCST-2022-R010809
 Validation of cervical cancer screening methods in Uganda: The National Cancer Management and Capacity building Project in Uganda (CANCAP UG) experience.
REFNo: HS6635ES

To assess multiple screening methods: VIA, PAP smear, HPV, and colposcopy, plus or minus biopsy.,To evaluate the indicators of screening accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of Visual Inspection with Acetic acid (VIA) test by comparing with the gold standard of disease status confirmed via histological results.,
 Uganda 2025-11-21 14:33:45 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Etheldreda Nakimuli-Mpungu
ID: UNCST-2020-R014808
 Secondary Data Analyses of the Predictors of Depression Treatment Outcomes and Mechanisms of Group Support Psychotherapy in the SEEK-GSP Trial and Translating Findings Through an Upgraded Online Training
REFNo: HS6789ES

Objective 1: Identify predictors of early treatment non-response to depression therapy among people living with HIV (PLWH). Objective 2: Identify psychological and behavioral mechanisms mediating the effect of Group Support Psychotherapy on depression outcomes. Objective 3: Strengthen and upgrade the existing SEEKGSP Academy digital training portal to enhance mental health support for people living with HIV (PLWH).
 Uganda 2025-11-21 14:31:49 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KASIMU SENDAWULA
ID: UNCST-2025-R019643
 Industrial Symbiosis and Scalability of Smallholder Farms in Uganda
REFNo: SS4430ES

To explore the perception of the smallholder farmers regarding the concept of scalability in Uganda

To identify the industrial symbiotic practices being undertaken by smallholder farmers in Uganda.

To investigate the influence of industrial symbiosis on scalability of smallholder farmers in Uganda.

Uganda 2025-11-21 14:20:24 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gladness Mtango E
ID: UNCST-2025-R017177
 The Nurses’ Perception of Their Immediate Supervisors’ Servant Leadership Behaviors and Their Sense of Work Effectiveness in Selected Ugandan Public Hospitals
REFNo: SS4419ES

•To explore the relationship between nurses’ perception of servant Leadership and their perceived access to work information such as willingness to share information.,•To determine the relationship between nurses’ perception of Servant Leadership and their perceived access to work resources such as needed equipment and materials.,•To explore the relationship between nurses’ perception of Servant Leadership and their perceived access to work opportunities such as challenging work and opportunities to learn new skills.,To explore if there are differences in job outcomes due to differences in the sizes of hospitals or the tenure of the nurse employee.,To survey and explore the perception of the nurses in the selected public hospitals in Uganda to determine if there is a relationship between their immediate supervisor’s servant leadership behavior and their job outcomes,
 USA 2025-11-21 14:16:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
BANGIRANA SEPHAS
ID: UNCST-2025-R020094
 USAGE OF PATIENT RECORDS MANAGEMENT SYSTEM, PSYCHOSOCIAL WORK ENVIRONMENT, WORK TEAM STABILITY, HEALTH CENTRE CHARACTERISTICS, AND QUALITY OF HEALTH CARE IN HEALTH CENTRE IVS IN SOUTH WESTERN UGANDA
REFNo: SS4395ES

General Objective
The aim of the study is to examine the relationship between usage of patient records management system, psychosocial work environment, work team stability, and the quality of health care in HC IVs in South Western Uganda, with health centre characteristics as a moderating variable.
Specific Objectives
i. To establish the relationship between usage of patient records management system usage and the quality of health care among the HC IVs in South-Western Uganda.
ii. To examine the relationship between psychosocial work environment and the quality of health care at HC IVs in South-Western Uganda.
iii. To assess the relationship between work team stability and the quality of health care HC IV in South-Western Uganda.
iv. To examine the combined effect of patient records management, psychosocial work environment, and team stability on the quality of health care at HC IVs in South-Western Uganda.
v. To assess the moderating effect of health centre characteristics in the relationship between psychosocial work environment and quality of health care in HC IVs in South Western Uganda.
 Uganda 2025-11-21 14:13:43 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 Safety of COVIDEX™ Therapy in adults: in Uganda: A randomized controlled open- label phase 1 clinical trial.
REFNo: HS6540ES

Overall aim
To validate the safety of COVIDEX™ therapy in adult Ugandans.

Specific objectives
Primary objective
To evaluate and document adverse events associated with COVIDEX™ among adults
in Uganda.

Secondary objective:
To determine the plasma concentration of berberine in adults receiving COVIDEX™ at
three different dose levels.
Uganda 2025-11-21 14:11:01 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Candidate Clinical Correlate as Prognostic Outcome for TB (C3PO) Study
REFNo: HS6545ES

Our specific aims are: 1. To evaluate end-of-treatment (EOT) biomarkers as predictors of recurrent TB 2. To evaluate novel cough and activity biomarkers as predictors of post-TB lung health
 Uganda 2025-11-21 13:53:39 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Rubatsimbira Katangaza
ID: UNCST-2024-R004595
 Social economic determinants of energy poverty at household level in Uganda
REFNo: SS4062ES

To what extend do socioeconomic factors determine energy poverty?
What are the energy poverty hotspots in Uganda?
What are the socioeconomic conditions of the most vulnerable households to energy poverty?
 Uganda 2025-11-21 13:49:30 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
DANIEL ELAMU
ID: UNCST-2025-R020928
 PREVALENCE OF MALARIA AND HIV IN UGANDAN CHILDREN WITH TRAUMATIC BRAIN INJURY; AN EARLY OUTCOME STUDY.
REFNo: HS6781ES

Primary objective: To determine the prevalence of malaria (by RDT and PCR) and HIV among children presenting with traumatic brain injury at Mulago National Referral Hospital in 8 months.
Secondary Objective: To assess the impact of malaria parasitemia and/or HIV co-infection on short-term functional recovery, measured by Health-Related Quality of Life (HRQoL) at one-month post-discharge.
Uganda 2025-11-21 13:47:46 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6565ES

To evaluate the efficacy of MK-8527 qm compared to FTC/TDF qd for the prevention of HIV-1 infection as assessed by the incidence rate per year of adjudicated HIV-1 infections To evaluate the safety and tolerability of MK-8527 qm compared to FTC/TDF qd.
 Uganda 2025-11-21 11:18:30 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssebiryo
ID: UNCST-2019-R001250
 Mid-Term Evaluation for the Stand Up for Sexual and Reproductive Health Rights Project
REFNo: SS4574ES

To establish a midline value for key performance indicators outlined in the project’s Performance Measurement Framework(PMF), allowing for a direct comparison with the baseline data. To assess progress toward the Outcome Indicators. To establish a midline value for tracking progress against these outcome indicators, as detailed in the project’s Performance Measurement Framework (PMF). To provide recommendations for strategic project improvements
 Uganda 2025-11-19 8:42:04 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
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