Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,779
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ouma Simple
ID: UNCST-2021-R012820
 Harnessing Parental Social Networks to Increase HIV Testing Uptake Among Children of At-Risk Parents in Uganda: A Parallel-Group, Two-Arm Quasi-Experimental Implementation Science Protocol
REFNo: HS5741ES

Objectives:

Main Objective

To Adapt, implement and evaluate maternal SNS to improve access to HIV testing services among children of FSW.

Specific Objectives

1. To adapt SNS that harnesses maternal SN for HIV testing in children of female sex workers
2. To implement the adapted HASHTAG intervention targeting CARP in Gulu City
3. To evaluate the effectiveness and implementation science outcomes of the HASHTAG project
 Uganda 2025-04-11 14:13:08 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Davis Hafashimana Simon
ID: UNCST-2025-R018006
 An investigation into the variability of Hemileia vastatrix on Robusta coffee in Uganda
REFNo: A591ES

Objectives 1. To assess the genetic diversity of Hemileia vastatrix on Robusta coffee in Uganda 2. To make a linkage of any observed diversity to disease distribution in Uganda
Uganda 2025-04-11 14:11:00 2028-04-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Venantius Bbaale Kirwana Bbaale
ID: UNCST-2024-R002370
 RISKY SEXUAL BEHAVIOUR AMONG YOUNG PEOPLE IN UGANDA’S ISLANDS, AN ANALYSIS OF SEXUALITY INFORMATION SOURCES AND COMPLETENESS.
REFNo: SS3785ES

4-Evaluate the level of completeness of sexuality information from various sources to young people in Uganda\'s island communities,3-Compare current and preferred sources of sexuality information sources among young people in the Uganda Island communities,2-Assess the barriers young people in island communities face in accessing sexuality information from different sources.,1-Explore young people’s perceptions of risky sexual behavior in the Uganda Island communities.,Examine young people’s perceptions of risky sexual behavior and how sexuality information sources and completeness influence sexual behavior, in Uganda Island communities.,
 Uganda 2025-04-11 14:09:55 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Javan Tindyebwa
ID: UNCST-2025-R017192
 ETHICAL LEADERSHIP, LEADER ACCOUNTABILITY, STAKEHOLDER PARTICIPATION, AND EDUCATION SERVICE QUALITY AT MAKERERE UNIVERSITY IN UGANDA
REFNo: SS3802ES

To examine the extent to which Stakeholder Participation mediates the relationship between Ethical Leadership and Education Service Quality in MUK in Uganda.,To establish the effect of Ethical Leadership on Education Service Quality in MUK in Uganda. ,To establish the effect of Stakeholder Participation on Education Service Quality in MUK in Uganda., To establish the effect of Leadership Accountability on Education Service Quality in MUK in Uganda,To examine the relationship between ethical leadership and leader accountability, and service quality and how these relationships are mediated by stakeholders at Makerere University.,
 Uganda 2025-04-11 14:04:32 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
EDIMOND SERWANGA
ID: UNCST-2025-R017659
 ASSESSING THE SITUATION OF TEACHERS IN PRIMARY AND SECONDARY SCHOOLS IN UGANDA
REFNo: SS3797ES

General objective To assess the teaching and learning situation of primary and secondary school teachers in both refugee and non-refugee settings across Uganda's West Nile and Karamoja sub-regions. 1.2.2. Specific objectives The study aims to address the following specific objectives: (i) To explore how teachers create, promote and utilise a supportive teaching environment that enhances their professional growth and well-being. (ii) To establish school and community practices that enhance child protection, well-being, and inclusion. (iii) To assess teachers’ practices on classroom management, instruction and assessment. (iv) To establish teachers’ understanding of the curriculum and how it informs teachers’ practices. (v) To establish language support strategies used by teachers to promote learning in schools.
Uganda 2025-04-09 17:19:38 2028-04-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lolem Lucy Chegem
ID: UNCST-2024-R004656
 Nature and Degree of Karamojong Pastoral Community Participation and Integration in Wildlife Conservation Interventions in Kidepo Valley National Park, North Eastern Uganda
REFNo: SS3755ES

1. To conduct a policy review towards the establishment of national (Uganda) wildlife conservation policies and guidelines on community participation and integration of Indigenous peoples' social and cultural practices
2. To examine the Karamojong Indigenous and traditional wildlife conservation values, practices, and livelihood needs associated with KVNP
3. To explore the nature of the Karamojong participation in wildlife conservation practices in the management of KVNP
4. To determine the degree of the Karamojong participation in wildlife conservation activities in KVNP
5. To explore the nature of the Karamojong integration in wildlife conservation practices in the management of KVNP
6. To determine the degree of the Karamojong integration in wildlife conservation activities in KVNP

 Uganda 2025-04-09 17:01:55 2028-04-09 Social Science and Humanities Non-Clinical Trial Degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
 Optimization and testing of ALRITE, a clinical decision support tool for management of respiratory illnesses in young children in primary care health facilities in Uganda
REFNo: HS5721ES

To pilot test ALRITE in 4 Ugandan health facilities after an optimization phase of iterative testing and ALRITE improvement.

1. To optimize ALRITE for health worker use through multiple cycles of reversal single-case experiments29,30* with 6-8 health workers per cycle.
2. Pilot-test study feasibility and the effectiveness of the optimized ALRITE tool on the diagnosis and management of wheezing illness and pneumonia in young children using interrupted time series (ITS) design.
3. Assess outcomes of implementation following ALRITE deployment and determinants of successful adoption using a sequential quant-> QUAL mixed methods design.
 Uganda 2025-04-09 16:40:46 2028-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 Evaluation of NT-proBNP in outpatient heart failure care in southwestern Uganda
REFNo: HS5796ES

Main Objective 1. Create and evaluate an algorithm for nurses using a point-of-care biomarker of heart failure (N-terminal-pro hormone B-type natriuretic peptide, NT-proBNP) to support heart failure management in Uganda. Specific Objectives 1. Identify an average baseline NT-proBNP for patients with HFrEF in the MRRH outpatient cardiology clinic. 2. Develop and compare the use of an algorithm for diuresis based on the NT-proBNP with standard of care diuretic plans for patients with HFrEF in the MRRH outpatient cardiology clinic 3. Evaluate the feasibility and acceptability of implementing an NT-proBNP based algorithm for heart failure care in Uganda
 USA 2025-04-09 16:31:41 2028-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 VacICoP: Chimpanzee Adenovirus Type 3-Vectored Marburg Glycoprotein (GP)-Expressing Vaccine (ChAd3-MARV)-Induced Correlates of Protection
REFNo: HS5469ES

This study aims to identify the immune correlates of protection (ICoPs) against Marburg virus disease (MVD) through comprehensive analyses of humoral and cellular responses in both vaccinated and infected individuals. ICoPs will be identified by studying human and non-human
primates (NHPs) that have either survived infection, succumbed to it, or been successfully immunised. The research aims to expedite regulatory approval and licensure by identifying the most effective and durable ICoPs against MVD.
Key objectives and deliverables include:
1. Identifying the MVD ICoPs
2. Detailed humoral and cellular immune profiles distinguishing protective from nonprotective anti-MARV immunity
3. Reference reagents and scalable high-throughput screening assays
4. Predictive statistical models for forecasting vaccination effectiveness
5. Integrated clinical, immunological, and demographic datasets
6. Regulatory guidance for new vaccines approval
7. Global collaborative data exchange framework
 Uganda 2025-04-09 16:29:46 2028-04-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
 Stakeholder perceptions and ethical considerations in gene therapy clinical trials for sickle cell disease in Uganda
REFNo: SS3570ES

Aim 1: To determine stakeholder perceptions of somatic gene therapy for SCD. We shall engage patient support and advocacy groups to ascertain knowledge gaps, expectations, and preferences regarding gene therapy. This will facilitate patient education and smooth implementation of research and development of affordable and accessible gene therapy in LMICs.

Aim 2: To examine the ethical, legal, and social considerations in somatic gene therapy clinical trials for SCD in a resource-limited setting. We shall use deliberative focus group discussions and key informant interviews to explore the ethical and social considerations in somatic gene therapy research in low-resource settings.

 Uganda 2025-04-09 16:28:31 2028-04-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Willbroad Byamukama
ID: UNCST-2022-R010646
 RURAL LANDLESSNESS AND FOOD INSECURITY IN UGANDA; A CASE OF KIGEZI SUB-REGION (KABALE, RUBANDA, RUKIGA, AND KISORO DISTRICTS)
REFNo: A561ES

iii. To establish workable strategies to address food insecurity in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,ii. To examine the effect of rural landlessness on food insecurity in Kigezi region (Kabale, Rubanda, Rukiga, and Kisoro).,i. To examine the causes of rural landlessness in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,The purpose of the study is to examine the effect of rural landlessness and food insecurity in, Uganda case of Kigezi region and come up with strategies to increase food security in Kigezi sub region with the rural landlessness.,
 Uganda 2025-04-09 16:09:36 2028-04-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
DICKSON NIWASASIRA
ID: UNCST-2024-R003949
 The Effectiveness of Electronic Media on Utilization of Health Services in a Rural Setting
REFNo: SS3705ES

I. Establish the electronic media channels used by different demographic segments of the rural population to access health information.
II. Determine the impact of electronic media on overall utilization of facility- based Health services in a rural setting.
III. Establish the effectiveness of different electronic media channels on utilization of facility-based health services among different demographic segments of the rural population.

 Uganda 2025-04-08 7:35:22 2028-04-08 Social Science and Humanities Non-Clinical Trial Degree Award
Glenn Ogolah
ID: UNCST-2025-R017145
 Asset Financing and Micro Leasing in Agriculture
REFNo: SS3726ES

1. Examining barriers and opportunities in asset financing and micro-leasing
adoption for smallholder farmers and microenterprises:
a. Identifying and analyzing the barriers and opportunities affecting the access of
asset financing solution amongst smallholder farmers
b. Examine gender differences in barriers to accessing asset financing for
smallholder farmers
c. Explore interactions among key stakeholders, including farmers,
microenterprises, SACCOs, and MFIs, to assess their roles and influences in
the asset financing landscape
2. Examining the role of clean energy assets in meeting farmers most urgent needs:
a. Identifying and analyzing the barriers and opportunities affecting the adoption
of clean energy assets by farmers
b. Exploring available productive assets in the market and their distribution
channels for rural farmers

 Kenya 2025-04-07 7:58:51 2028-04-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Josephine  BIRUNGI
ID: UNCST-2024-R003480
 A Roadmap towards the successful deployment of a fixed dose combination of Artemether-Lumefantrine+Amodiaquine (FDC ALAQ) in Uganda (DeTACT Study)
REFNo: SS3706ES

Main Objective: to identify and address obstacles in implementation and deployment of FDC ALAQ at an early stage, and contribute to the smooth introduction of FDC ALAQ in Uganda.
Specific Objectives:
To identify and engage with key national stakeholders involved in Malaria control and introducing new antimalarials in Uganda;
ii. To obtain understanding into relevant policy, regulatory and implementation procedures of new antimalarials and to identify areas that require strategic attention before any new antimalarials are introduced in Uganda;
iii. To develop a practical roadmap that can be used for the effective introduction and deployment of FDC ALAQ in Uganda aiming to control and contain artemisinin resistance in Uganda.

 Uganda 2025-04-03 16:55:55 2028-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robinson Amanyiraho
ID: UNCST-2024-R016357
 Impact of the Growing Expertise in E-health Knowledge and Skills (GEEKS) Program in Reducing Immunization Defaulters and Enhancing Timely Reporting of Vaccine-Preventable Disease Cases in Uganda
REFNo: HS5737ES

Goal:
The goal of this study is to evaluate the contributions and sustainability of GEEKS Cohort 1 projects, while also providing actionable recommendations to enhance the effectiveness of current and future implementations of the GEEKS program.
Specific Objectives
1.
To document and analyze the contributions of GEEKS Cohort 1 projects in strengthening Vaccine Preventable Disease Surveillance (VPDS) and routine immunization coverage.
2.
To assess the sustainability of GEEKS Cohort 1 projects and identify factors influencing their long-term impact.
3.
To provide evidence-based recommendations for strengthening the design and implementation of current and future GEEKS program initiatives.
 Uganda 2025-04-02 9:37:17 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geofrey Musinguzi
ID: UNCST-2024-R015961
 HIV Prevention Program Outcomes: Measurement of accessibility, and utilization of key HIV prevention services and linkage to care among adolescent girls and young women, female sex workers, and people who inject drugs in Uganda – A Rapid Coverage Survey
REFNo: HS5730ES

Main objective
The survey’s main objective is to measure the HIV prevention program outcomes among key and priority populations, particularly the AGYW, FSWs, and PWIDs, to inform ongoing and future HIV prevention programs (among such populations) in Uganda.

Specific objectives
1. To assess access to key HIV prevention services and products among AGYW, FSWs, and PWIDs in Uganda.
2. To assess the utilization of key HIV prevention products and services among AGYW, FSWs, and PWIDs in Uganda.
3. To measure the proportion of HIV-positive AGYW, FSWs, and PWIDs linked to HIV/AIDS, STD care and desired health services.

 Uganda 2025-04-02 9:35:25 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Achen
ID: UNCST-2025-R016855
 PARTICIPATORY INTERVENTION RESEARCH TO ADDRESS CHILD EXPLOITATION IN KARAMOJA, UGANDA
REFNo: SS3733ES

i. Explore the main forms of exploitation and modern slavery in Napak and Moroto Districts;
ii. Assess interventions and program components that should be prioritized concerning child exploitation, bearing in mind the major intersecting issues such as gender discrimination, food security, and climate change;
iii. Explore the traditions, narratives, and cultural beliefs that could be mobilized as assets to the program; and lastly,
iv. Map out the key actors and influencers in the child exploitation debate.

 Uganda 2025-04-02 9:26:44 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sebastian Linnemayr
ID: UNCST-2021-R012696
 R01 Study “INcentives and ReMINDers to Improve Long-term Medication Adherence” (INMIND)
REFNo: SS3732ES

Main Objective
1. We propose to optimize an adaptive intervention using the INMIND approach in a Stage III efficacy randomized trial using a two-stage SMART design in Uganda. All clients (including the control group) will receive information about the importance of behavioral routines, as is part of the standard adherence counseling for treatment initiators and create personalized ART adherence anchoring strategies. We will first enroll patients into an Wisepill use only phase for one month. We will then randomize them to receive either usual care / information only or low-cost daily text messages. All clients will have the opportunity to select a new anchoring plan in the first two months, so that they then have another 4-month period during which to establish a routine. Those who if fail to take their ART pills very regularly, meaning at the same time for at least 80% of the days at the end of month three will be re-randomized to one of two more intensive interventions for the subsequent three months: monthly or monthly escalating prizes.

The Specific Aims are to:
SA1 (Primary): Test the first-stage main effect of Messages vs. Control on the maintenance of ART adherence (primary outcome) and viral suppression (secondary outcome).
SA2 (Secondary): Examine (a) the second-stage main effect of receiving monthly vs. monthly escalating incentives on the primary and secondary outcomes among first-stage non-responders, and (b) whether changing one’s anchoring plan at month two moderates the effect of monthly and monthly escalating incentives.
SA3. Synthesis Phase: Perform a cost-effectiveness analysis including a comparative analysis of the INMIND components among first-stage responders and non-responders and conduct information dissemination activities in Uganda after completion of the trial.

 USA 2025-04-02 9:23:18 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Henry Kyobe Bosa
ID: UNCST-2021-R013941
 UNDERSTANDING THE SOCIO-ECOLOGICAL AND BEHAVIORAL DRIVERS OF MPOX DISEASE IN AFRICA
REFNo: HS5719ES

General Objective
To assess the state of knowledge, attitudes, and practices, including socio-ecological and behavioral determinants of health considerations, regarding MPXV acquisition and vaccine uptake in Uganda.
Specific Objectives
1. To assess the determinants of the Mpox disease spread and modes of transmission
2. To determine the community’s knowledge, attitude, practices, and perception on Mpox disease
3. To evaluate health-seeking behavior for Mpox disease
4. To identify the barriers and facilitators to Mpox vaccine uptake

 Uganda 2025-04-02 9:21:50 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Walter Akwat
ID: UNCST-2024-R003452
 Uganda Multi-Sectoral Needs Assessment (MSNA) 2024
REFNo: SS3727ES

• Conduct a thorough inter-sectoral analysis to assess the magnitude and
severity of humanitarian needs and conditions among refugee and host
community households across all 13 formal refugee settlements across
the country and refugee concentrations in Kampala.
• Identify variations in humanitarian needs across different areas of study,
population groups, and household vulnerability profiles.
• Compare key findings of the 2024 MSNA with the Vulnerability and
Essential Needs Assessment (VENA) (2019) and 2018 MSNA.
• Offer insights into inter-sectoral needs to inform prioritization of refugee
response efforts and strategic planning.
Uganda 2025-04-02 9:20:09 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Agrace Atwikirize
ID: UNCST-2024-R002716
 Stressors, Coping Strategies, Hope and Academic Perfomance of Teacher-Trainees in Universities in Central Region, Uganda
REFNo: SS3485ES

i. To find out the variations of stressors with biodata among teacher-trainees in universities in Central Region, Uganda.
ii. To investigate the relationship between stressors and coping strategies among teacher-trainees in universities in Central Region, Uganda.
iii. To establish the relationship between coping strategies and academic performance among teacher-trainees in universities in Central Region, Uganda.
iv. To assess if the relationship between stress and academic performance is mediated by coping strategies among teacher-trainees in universities in Central Region, Uganda.
v. To determine the mediating effect of coping strategies and hope on the relationship between stressors and academic performance among teacher-trainees in universities in Central Region, Uganda.

Uganda 2025-04-02 9:18:20 2028-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Mohamed  Ali Bashir
ID: UNCST-2024-R002641
 PREVALANCE AND FACTORS ASSOCIATED WITH IMMEDIATE ADVERSE PERINATAL OUTCOMES AMONG WOMEN WITH UNINTENDED PREGNANCIES DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5383ES

General Objectives
To determine prevalence and factors associated with immediate adverse perinatal outcome among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.
Specific Objectives
1. To determine prevalence of immediate adverse perinatal outcomes among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.
2. To determine factors associated with immediate adverse perinatal outcome among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.

 Somalia 2025-04-02 9:16:24 2028-04-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Cecilia Akatukwasa
ID: UNCST-2024-R002112
 Feasibility and acceptability of the Vxnaid-Immunization Information System (Vxnaid-IIS) for improved Immunization Monitoring and Data Management through Digitization in Wakiso district.
REFNo: SS3734ES

4. To explore stakeholder’s insights and perspectives into future use of Vxnaid-Immunization Information System including sustainability,3. To assess the barriers and enablers to implementation of the Vxnaid-Immunization Information System across four HSDs and four Municipal councils in Wakiso district.,2. To explore key stakeholders’ perceptions, attitudes and acceptance of the Vxnaid-Immunization Information System,1. Explore key stakeholders’ perspectives on practicality, ease of use and overall experience with integrating Vxnaid into current Immunization Information systems across four HSDs and four Municipal councils in Wakiso district.,
 Uganda 2025-04-02 9:08:21 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
William Blackmon
ID: UNCST-2025-R017006
 Consumer Protection Surveys - Uganda
REFNo: SS3650ES

The project aims to:
• Measure consumer protection risks associated with digital financial services (DFS) usage in Uganda
• Track consumer protection risks across two survey rounds
• Create a comparable cross-country analysis (the survey is also carried out in 10 other countries)

 USA 2025-04-02 9:06:12 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maxensia owor
ID: UNCST-2021-R014003
 An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase: NeoSep1
REFNo: HS5639ES

In Part 2, a secondary objective is to provide a ranking of clinically relevant antibiotic regimens based on other efficacy and safety secondary outcomes, as well as on health economic measures and the potential selection of resistance. The trial data will provide data to inform the balance between efficacy, safety, costs (and cost-effectiveness and equity, using health economic analysis) and propensity for resistance selection (based on microbiology tests) that will influence facility-level and national decision-making about adoption of studied regimens, and potential future inclusion in WHO guidelines.,In Part 2, the primary objective is to provide a ranking of eight different clinically relevant antibiotic regimens for first-line empiric and second-line (after lack of response/deterioration) treatment in terms of 28-day mortality as the primary outcome measure. It will flexibly compare these multiple different relevant treatment regimens to enable the trial to be run in sites worldwide with very different background rates of different pathogens, of resistance and patterns of routine clinical care by randomising each participant to locally relevant antibiotic regimens agreed prior to site initiation. The trial will ensure generalisability by focusing inclusion based on clinical symptoms associated with high mortality risk in the NeoOBS study, which have been developed into a novel neonatal sepsis severity score – the NeoSep Severity Score.,
 Uganda 2025-04-02 9:04:16 2028-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Gloria Lubega
ID: UNCST-2025-R017180
 A retrospective review of patients admitted with SARS-COV-2 at Entebbe regional referral hospital in Uganda across multiple waves.
REFNo: HS5695ES

I. To evaluate the mortality rate, risk factors associated with mortality and prolonged hospital admission among patients admitted with severe COVID-19 disease at ERRH.
II. To determine the time to discharge of patients admitted with severe COVID-19 disease at ERRH.
III. To describe the characteristics of patients across different age groups admitted with severe COVID-19 at Entebbe Regional Referral Hospital
IV. To describe treatment options offered to patients admitted with severe COVID-19 disease with reference to Uganda MoH and WHO recommended treatment options.
V. To compare characteristics of patients who were vaccinated against COVID-19 admitted with severe disease and unvaccinated patients admitted with severe COVID-19 disease.

 Uganda 2025-04-02 9:01:54 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Kaddumukasa
ID: UNCST-2020-R001798
 Building a Collaborative Research and Training Platform for HIV and Rheumatic and Musculoskeletal Diseases in Uganda
REFNo: HS5606ES

Objective 1. Establish the Ugandan Registry of RMDs in HIV (GEMINI), to create a foundation for future prospective studies on HIV and RMDs.
Objective 2. In a pilot study, among a subset of participants from GEMINI with both RA and HIV, compared to participants with HIV only and RA only, explore the impact of co-morbid disease status on markers of bone metabolism, bone mineral density, as well as quality of life and functional disability.
Uganda 2025-04-02 9:00:14 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sylvia Kusemererwa
ID: UNCST-2019-R001717
 A phase III, multi-center, randomized, placebo-controlled, double-blind study to assess efficacy and safety of crizanlizumab (5 mg/kg) versus placebo, with or without hydroxyurea/hydroxycarbamide therapy, in adolescent and adult Sickle Cell Disease patients with frequent vaso-occlusive crises
REFNo: HS5607ES

To assess the efficacy and safety of crizanlizumab (5 mg/kg) versus placebo, with or without
hydroxyurea (HU)/hydroxycarbamide (HC) , on VOC rate in Sickle Cell Disease (SCD) patients aged 12 years and older who experience frequent vaso-occlusive crises (VOCs)
Primary Objective
1. To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of VOCs* that are HCP managed (including VOCs leading to management at a health care facility or those via remote consultation) over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in 12 months prior to the screening visit).
Secondary Objectives
1. To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without
hydroxyurea/hydroxycarbamide, on the annualized rate of all VOCs including VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) and VOCs that are self-managed without recommendations from HCP during the event over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in the 12 months prior to the screening visit).
2. To evaluate the annualized rate of VOCs by type of management between treatment arms over the planned 52-week treatment period:
 VOCs that are HCP-managed at a health care facility
 VOCs that are HCP-managed via remote consultation
Page 4 of 18
 VOCs that are self-managed without recommendations from HCP during the event
 VOCs that are HCP-managed via remote consultation or self-managed without recommendations from HCP during the event
 Uganda 2025-04-02 8:58:47 2028-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Aloysious Ssemaganda
ID: UNCST-2023-R008046
 Clinical Performance of i.Mune CD4 diagnostic assay amongst people living with Human immunodeficiency virus (HIV) in Uganda (CPHL-CPSP_001)
REFNo: HS5680ES

The primary objective of this study is to evaluate the clinical performance and validity of the i.Mune CD4 diagnostic assay compared to WHO pre-qualified and CE-marked Abbott PIMA CD4 test using matched liquid and dried venous blood as well as capillary dried blood specimen
collected from people living with HIV in Uganda.

Secondary objectives of this study are:
-To validate the i.Mune CD4 diagnostic assay using the Applied Biosystems™ QuantStudio 5 PCR System in Uganda to support WHO pre-qualification.
-To establish trueness of measurement of the i.Mune CD4 diagnostic assay using the LightCycler 480 Instrument II and the LightCycler PRO in comparison to the reference method (Abbott CD4 PIMA) to support CE-marking of the assay.
 Uganda 2025-04-02 8:53:21 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CAROLYNE OLEO
ID: UNCST-2024-R003845
 CHARACTERIZATION OF CLINICAL OUTCOMES AMONG AMBULATORY GYNECOLOGY SURGERY RECIPIENTS AT KYABIRWA SURGICAL CENTER, BUDONDO SUB COUNTY, JINJA CITY
REFNo: HS5656ES

3. To disaggregate the clinical outcomes of among ambulatory gynecological surgery recipients at Kyabirwa surgical center, with their characteristics ,2. To develop a typology of the clinical outcomes among ambulatory gynecological surgery recipients at Kyabirwa surgical center, Budondo sub county, Jinja city,1. To classify the clinical outcomes among ambulatory gynecological surgery recipients at Kyabirwa surgical center, Budondo sub county, Jinja city,To characterize the clinical outcomes among ambulatory gynecological surgery recipients at kyabirwa surgical center, Budondo sub county, Jinja city,
 Uganda 2025-04-02 8:52:03 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Assessing durability of PermaNet Dual and PermaNet 3.0 under field conditions in Northern Uganda.
REFNo: HS5657ES

1. To compare the attrition and physical integrity of PermaNet Dual nets to PermaNet 3.0 nets in multiple locations across Northern Uganda over a three-year period, and to estimate median LLIN survival.
2. To characterize the chemical and entomological attributes of PermaNet 3.0 and PermaNet Dual nets over a period of three years after the mass distribution campaign.
3. To provide insight into the community acceptance of PermaNet Dual relative to PermaNet 3.0, and describe social and behavioural aspects related to net use and net care.
4. To assess the impact of net use and net care practices on the functional survival and insecticidal activity of the LLINs across the districts and across time.

 Uganda 2025-04-02 8:50:02 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Asiimwe
ID: UNCST-2019-R000059
 Uganda Lung Health Study
REFNo: HS5678ES

To identify individuals at highest risk for COPD early in the disease course and intervention targets for preventing disease progression among young adults.
 Uganda 2025-04-02 8:46:08 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
 A phase III, Multicenter, Randomized, Placebo Controlled, Double-blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises
REFNo: HS5274ES

Primary Objective: To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of VOCs* that are HCPmanaged (including VOCs leading to
management at a health care facility or those managed via remote consultation) over the planned 52-week treatment period in SCD
patients aged 12 years and older with a history of frequent VOCs (4-12 events in 12 months prior to the screening visit).

Secondary Objective: Key secondary objective:

To compare the efficacy of 5 mg/kg of
crizanlizumab versus placebo, with or without
hydroxyurea/hydroxycarbamide, on the
annualized rate of all VOCs including VOCs that are HCP-managed (including VOCs leading to
management at a health care facility or those managed via remote consultation) and VOCs that are self-managed without recommendations from HCP during the event over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in the 12 months prior to the screening visit).

To evaluate the annualized rate of VOCs by type of management between treatment arms over the planned 52-week treatment period:
VOCs that are HCP-managed at a health
care facility
• VOCs that are HCP-managed via remote
consultation
• VOCs that are self-managed without
recommendations from HCP during the
event
• VOCs that are HCP-managed via remote
consultation or self-managed without
recommendations from HCP during the
event

• To evaluate the time to first VOC that is HCPmanaged (including VOCs leading to
management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.

To evaluate the proportion of participants free from VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.

To evaluate the duration of VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.

To evaluate the safety and immunogenicity of crizanlizumab 5 mg/kg over the 2-year study
period.

To explore the efficacy of crizanlizumab 5 mg/kg over the 2-year study period.

To explore the proportion of VOCs that are selfmanaged without recommendations from HCP during the event, versus VOCs that are HCP-managed (including VOCs leading to
management at a health care facility or those managed via remote consultation) between treatment arms over the planned treatment period of 52 weeks.

To explore the proportion of VOCs that are HCP-managed via remote consultation versus VOCs that are HCP-managed at a healthcare facility between treatment arms over the planned 52-week treatment period.

To explore the incidence rates of all VOCs,
VOCs that are HCP-managed at a healthcare
facility, VOCs that are HCP-managed via remote consultation, VOCs that are HCP-managed,VOCs that are self-managed without
recommendations from HCP during the event,
VOCs that are HCP-managed via remote
consultation or self-managed without
recommendations from HCP during the event, by treatment arm.

To explore quality of life in each treatment arm (ASCQ-Me Short Forms: emotional impact, sleep impact, and joint stiffness).

To explore healthcare facility resource utilization (inpatient hospital admission, emergency room visit, urgent care/clinic visit, infusion center visit)between treatment arms over
the planned 52-week treatment period.

To explore the pharmacokinetics (PK) profile of crizanlizumab at 5 mg/kg.

To explore the pharmacodynamics (PD) (Pselectin inhibition) of crizanlizumab at 5 mg/kg.

To explore biomarkers [p-selectin (free and
total)] and CRP].

To explore exposure-response relationship.
 Uganda 2025-04-02 8:43:56 2028-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Taremwa Danison Danison
ID: UNCST-2024-R002981
 AN OPTIMIZED ENSEMBLE DEEP LEARNING MODEL FOR MAIZE YIELD PREDICTION
REFNo: SIR375ES

General Objective of the Study

The general objective of the study will be to develop an optimized ensemble deep learning model to improve the accuracy of maize yield prediction, thereby enhancing decision-making by stakeholders in the agriculture sector.
Specific Objectives of the Study

i. To investigate the challenges of the current yield forecasting models and remote sensing technologies that will be used to generate variables for predicting maize yields using remote sensing data.
ii. To design and develop an optimized CNN-LSTM model using Bayesian approaches for the prediction of maize yields in Uganda.
iii. To evaluate the performance of the developed model for maize yield estimation.

 Uganda 2025-04-02 8:32:18 2028-04-02 Engineering and Technology Non-Clinical Trial Degree Award
Moses Sembatya Nixon
ID: UNCST-2024-R015771
 Baseline Study of Norms and Behavioral Drivers of Child Marriage and Female Genital Mutilation in Uganda
REFNo: SS3765ES

This study aims to provide crucial insights into the prevalence, drivers, and consequences of child marriage (CM) and female genital mutilation (FGM) in Uganda through a comprehensive baseline study. By assessing social norms, knowledge, attitudes, and practices related to CM and FGM, the study seeks to inform targeted interventions and policy decisions.
Uganda 2025-04-02 10:33:36 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rogers Ssebunya
ID: UNCST-2025-R016712
 Supporting Health System Readiness and Quality for Scaled Delivery of Self-Injectable Contraception: The Delivering Innovation in Self-Care (DISC) 2.0 Study Version 1.1
REFNo: HS5767ES

1. To describe health facility readiness to provide voluntary DMPA-SC SI within the existing contraceptive method mix in DISC-supported facilities in Uganda.
2. To describe quality of contraceptive counseling and client experiences among clients receiving injectables at DISC-supported facilities in Uganda.
3. To understand clients’ self-efficacy and confidence around DMPA self-injection immediately post-training and at 4-months follow-up in Uganda.
4. To improve understanding of DMPA-SC ‘take home’ units, including dispensation practices, provider and client preferences, storage, and usage, and disposal at initiation and 4-months follow-up.
 Uganda 2025-04-02 10:31:32 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Field Performance Evaluation of the Genbody ConfiSign HIV Self-Test in Uganda
REFNo: HS5760ES

To evaluate the field diagnostic performance and operational characteristics; usability, acceptability, and feasibility of the Genbody ConfiSign HIV ST in Uganda.

Specific objectives
a) To determine the field diagnostic accuracy (sensitivity, specificity, positive predictive value, and negative predictive value) of the Genbody ConfiSign HIV Self Test compared with the Wondflo HIV Self test (Guangzhou, China).

b)To evaluate the operational characteristics; feasibility, acceptability, and usability of the Genbody ConfiSign HIV ST in selected health facilities.

 Uganda 2025-04-02 10:25:15 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Odendi Gideon
ID: UNCST-2024-R002130
 MENTAL HEALTH CHALLENGES, ADVERSE CHILDHOOD EXPERIENCES AND INTERPERSONAL PSYCHOTHERAPY AMONG ADOLESCENTS AT KAMPIRINGISA NATIONAL REHABILITATION CENTER, CENTRAL UGANDA
REFNo: HS5763ES

1. To determine the prevalence of mental health challenges (Depression, PTSD, and alcohol substance use disorders) and adverse childhood experiences (ACEs) among adolescents at Kampiringisa National Rehabilitation Centre (KNRC).
2. To examine the relationship between ACEs and mental health challenges, with social support as a mediator among adolescents at KNRC.
3. To explore the experiences and perceptions of adolescents regarding the effectiveness of existing counseling practices in reducing depressive symptoms among adolescents at KNRC.
4. To identify the socio-cultural factors, institutional policies, and individual characteristics that influence the feasibility, acceptability, and effectiveness of Group Interpersonal Therapy (Group IPT) in reducing depressive symptoms at KNRC.
5. To evaluate adolescents' experiences and perceptions of the feasibility, acceptability, and effectiveness of Group IPT compared to the existing counseling practices at KNRC.

 Uganda 2025-04-02 10:00:01 2028-04-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Felix Bongomin
ID: UNCST-2020-R014224
 Chronic Pulmonary Aspergillosis: Optimization of Therapy, Immunogenetic Screening, and Diagnosis in Uganda [CPA_OPTIONS_Phase I: A Prospective Cohort Study]
REFNo: HS5799ES

The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,
 Uganda 2025-04-01 17:44:43 2028-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 The Integrated Management of Chronic Lung Illnesses in Uganda
REFNo: HS5728ES

Aim 1: To determine the prevalence of and factors associated with chronic respiratory illnesses e.g., asthma, chronic obstructive pulmonary disease among presumptive TB patients who test negative for TB on GeneXpert testing

Aim 2: (a) To determine the prevalence of, factors associated with post TB lung disease (PTLD) among patients who complete TB treatment (b) To determine the effect of post TB lung care on health related QoL among patients with PTLD

Aim 3: To determine barriers and facilitators for linkage to treatment for patients referred for chronic lung care

Aim 4: To document the cost per asthma/COPD case found during integrated community-based screening.
 Uganda 2025-04-01 17:31:43 2028-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
george paasi
ID: UNCST-2020-R014619
 THE CLINICAL SPECTRUM, GEOSPATIAL DISTRIBUTION AND GENETIC MODIFIERS OF SEVERE MALARIA AMONG CHILDREN WITH SICKLE CELL DISEASE IN EASTERN UGANDA.
REFNo: HS5714ES

i) To determine the effect of host RBC polymorphisms on the risk and severity of malaria.
ii) To determine the Geospatio-temporal distribution of the malaria-sickle cell disease syndemic in Uganda.
iii) To determine the clinical spectrum of severe malaria among children with SCA in eastern Uganda.

 Uganda 2025-04-01 17:21:57 2028-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ERICK SSEGUJJA
ID: UNCST-2021-R012964
 Partnerships for Stronger Knowledge Systems in Africa (KNOSA): Lessons from Uganda
REFNo: HS5716ES

Specifically, the implementation research has the following objectives;
1. To characterise the nature and functioning of the different components of the current national knowledge system, ??with a focus on the health sector.
2. To explore constraints and challenges affecting the capacity of Uganda’s national knowledge systems.
3. To document and assess the current interventions to strengthen the national knowledge system?
4. To explore opportunities for strengthening the capacity of the national knowledge system to advance evidence-informed decision making in Uganda’s health sector.

Uganda 2025-03-25 11:14:05 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
 INTEGRATED FEMALE SEXUALLY TRANSMITTED INFECTION TESTING FOR HIV EPIDEMIC CONTROL THROUGH PREP (IN-STEP)
REFNo: HS5715ES

a) To conduct an individually randomized effectiveness implementation trial of SRST plus cSTI testing to increase PrEP use among African women at high HIV risk.
b) To perform a mixed-methods, implementation science evaluation of female cSTI testing for improving PrEP use for HIV prevention.
c) To determine the most efficient, population-level female cSTI testing strategies to reduce HIV incidence in African settings.

Uganda 2025-03-25 11:13:20 2028-03-25 Medical and Health Sciences Clinical Trial Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
 Developing a robust interdisciplinary-informed WASH framework for the prevention and elimination of the wicked public-health problem of schistosomiasis (WickedSchisto)
REFNo: HS5707ES

I. What are the true health, economic and societal impacts of schistosomiasis?
a) Characterise what quality of life means to individuals living in Schistosoma endemic areas in Cameroon and Uganda, and how this is affected by infections, WASH access, environmental, spatial, social and other determinants.
b) Measure the diverse impact of schistosomiasis on individual’s and household’s quality of life.
c) Quantify the economic costs associated with schistosomiasis to individuals and society.
d) Develop and validate a field-suitable morbidity marker for mapping and monitoring disease resolution.
II. What are the most cost-effective combinations of WASH and MDA interventions?
a) Test the hypothesis that MDA refusal, due to fear of side effects, is linked with latrine access.
b) Characterise relative contributions of existing WASH on reducing reinfection post MDA: risk to self.
c) Quantify environmental force-of-infection and the impact of ‘risk to self’ and ‘risk to
Uganda 2025-03-25 11:11:44 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Riley Derby Nicholas
ID: UNCST-2025-R017680
 Impacts of early social life on social and physical development in mountain gorillas
REFNo: NS946ES

Study social and physical change in immature mountain gorillas in Bwindi Impenetrable National Park, in collaboration with Bwindi Gorilla Project, through combining behavioral, hormonal, and non-invasive growth measures
 USA 2025-03-25 11:02:11 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Erika Sininärhi
ID: UNCST-2025-R017295
 Physiological correlates of variation in personality traits in the banded mongoose Mungos mungo
REFNo: NS942ES

1) To determine the relationship between social rank, prenatal androgen exposure, and personality. 2) To investigate whether individual differences in facial thermal patterns are connected to personality, behaviour and stress reactivity.
Finland 2025-03-25 11:01:27 2028-03-25 Natural Sciences Non-Clinical Trial Degree Award
David Hayman T. S.
ID: UNCST-2023-R006403
 One Health, multiple factors: an interdisciplinary investigation of emerging infectious disease
REFNo: NS924ES

Infectious diseases significantly impact global health, affecting both humans and animals. Zoonotic diseases, which are transmitted between animals and humans, pose particular risks in regions with high human-wildlife interaction. One such region is Uganda, specifically around Bwindi Impenetrable National Park (BINP), where communities live in close proximity to domestic and wild animals.

The objectives of this research are to:

Identify and quantify zoonotic pathogens in fecal samples from various animal species.

Assess pathogen prevalence across different species.

Analyze microbial community structures and antimicrobial resistance genes.
 New Zealand 2025-03-25 11:00:19 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
 Using patient journey mapping approach to understand and improve post-abortion care within routine health care services
REFNo: HS4137ES


General objective

The general objective of this study is to use a journey mapping approach to understand client experiences as they navigate abortion services, and gaps in services, in order to improve PAC service delivery, client experiences and outcomes within the health care system.
Specific objectives

The specific objectives of the journey mapping approach include:

1. To document client experiences at different stages of post-abortion care-seeking.
2. To understand the current service provision processes for clients seeking post-abortion care services and identify gaps and unmet needs in these services.
3. To evaluate comprehensiveness of care and identify interventions to improve care.
4. To compare patient experiences with established standards of care

The specific objectives of the survey include:
1. To characterize the type and range of contraceptive and abortion-care services available for women who seek care at health facilities.
2. To determine whether women, including young women, receive comprehensive counseling on choices related to manual vacuum aspiration (MVA), medical abortion (MA) and contraception and which factors are related to receipt of such counselling.
3. To determine whether family planning and abortion services are provided with respect and compassion.

 Uganda 2025-03-25 10:56:04 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Karen Bailey M.
ID: UNCST-2024-R003544
 Understanding invisible socio-environmental systems through pesticides across human-wildlife interactions
REFNo: SS3710ES

To model simulations of the interactions within the SES, illustrating the feedback mechanisms between pesticide use, environmental changes, and human-wildlife well-being,To quantify pesticide exposure and associated health outcomes in humans and wildlife, with a focus on spatial and temporal trends,To assess socio-economic and environmental factors influencing farmers\' decisions regarding pesticide use,To investigate the socio-environmental drivers and molecular-level impacts of pesticide use in a tropical forest-agricultural mosaic and develop strategies that balance agricultural productivity with biodiversity conservation among communities around the Kibale National Park ,
 USA 2025-03-25 10:53:06 2028-03-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Integrating management of alcohol use, intimate partner violence, and menopausal transition into HIV care for women living with HIV in Uganda
REFNo: HS5750ES

To explore the unique health challenges faced by women living with HIV in Uganda related to intimate partner violence, menopausal transition, and alcohol use disorder (AUD), focusing on distinct age groups to inform targeted health interventions
 Uganda 2025-03-19 13:02:04 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5638ES

To estimate the site-specific IR of P. falciparum infection by rapid diagnostic test (RDT) testing, overall and by age group (5-11 years, 12-17 years, 18-60 years) during the active detection of infection period.
 Uganda 2025-03-19 12:57:39 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 Clonal Hematopoiesis: A Global Perspective on the Impact of CH on Alzheimer’s Disease in Sub-Saharan Africa
REFNo: HS5533ES

Main Objective
1. The aim of this proposed work is to compare the frequency and type of clonal hematopoiesis (CH) mutations in age-matched African American and Ugandan populations. We intend to determine the correlation between specific CH-associated mutations and development of Alzheimer’s Disease in both a Ugandan and African-American population.

Specific Objectives
1. Compare the frequency of CH in an elderly African American versus elderly Ugandan population.
2. Compare the types of CH mutations in an elderly African American versus elderly Ugandan population.
3. Determine the correlation between specific CH-associated mutations and the development of AD in a Ugandan population.
 Uganda 2025-03-19 12:53:37 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
 PARTICIPATION OF FEMALE DOCTORATE HOLDERS IN SCIENCE, TECHNOLOGY AND INNOVATION: AN EXAMINATION ON GENDER EQUITY, INCLUSIVITY AND INTERSECTIONALITY IN UGANDA
REFNo: SS3712ES

a) To examine the demographic and professional characteristics of female doctorate holders in Uganda
b) To assess the intersectional challenges faced by female doctorate holders in Uganda
c) To provide data-driven insights for integrating intersectionality into UNCST’s grants system
 Uganda 2025-03-18 13:09:22 2028-03-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Wismayer
ID: UNCST-2019-R000483
 The microbiome as an aetiological factors in colorectal carcinoma in Ugandan patients
REFNo: HS5644ES

1. To investigate the frequency of carriage of faecal P. micra in Ugandan CRC patients and controls by 16S rRNA sequencing and PCR and assess its potential as a non- invasive biomarker compared to other bacteria (Study 1).

2. To explore the associations of P.micra and F.nucleatum, the general tumour microbiome, the intra-tumour immune response and the tumour MSI status within the tumour itself. P.micra and F.nucleatum will be determined by PCR, the tumour microbiome by 16S rRNA sequencing and the tumour immune response both pathologically and by the numbers of infiltrating lymphocytes a key prognostic marker. MSI and MSS status will also be identified (Study 2).

3. To analyse the bacterial content of faeces using 16S rRNA sequencing in relation to the clinical features and MSI/MSS status of CRC in Ugandan patients and controls using network analysis in Ugandan patients. To identify bacteria positively and negatively associated with Ugandan bowel cancer carriage (Study 3).

4. To determine the prevalence of cancer related stool toxins, pks, FadA, and ETBF in Ugandan colorectal cancer patients and controls using quantitative PCR assays on faeces (Study 4).

5. To compare the above findings with those of CRC patients and controls from the international microbiome network in Ghana, India, Vietnam, Argentina and England (Study 5).

 Malta 2025-03-18 13:03:54 2028-03-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shahiid Kiyaga
ID: UNCST-2021-R007055
 Genetic Diversity and Transmission Intensity Heterogeneity of Plasmodium falciparum in Malaria Endemic Regions in Uganda
REFNo: HS5697ES

General Objective
To analyze the genetic diversity of P. falciparum and the heterogeneity in malaria transmission intensity in high-endemic areas of Uganda.
Specific Objectives
1. To assess the genetic diversity and population substructure of P. falciparum in high endemic areas of Uganda by quantifying allelic variation and estimating population structure parameters using F_ST (fixation index) and principal component analysis (PCA).
2. To characterize the heterogeneity in transmission intensity in high endemic areas of Uganda using P. falciparum targeted amplicon genomic data and malaria epidemiological parameters.
3. To develop and apply advanced machine learning models to predict geographical origins of P. falciparum parasites in Uganda using whole-genome sequence data.
 Uganda 2025-03-14 19:14:47 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Racheal Ninsiima
ID: UNCST-2020-R014564
 Effect of blockchain technology on the performance of barley farmers in eastern Uganda
REFNo: A536ES

i) To determine farmers’ behavioural intention to accept BCT in Uganda’s eastern barley producing region.
ii) To examine the factors that influence adoption and extent of use of BCT among barley farmers in eastern Uganda.
iii) To determine the effect of BCT on barley farmers’ productivity and gross margin in eastern Uganda
iv) To develop suitable BCT implementation framework among barley farmers in eastern Uganda.

 Uganda 2025-03-14 19:13:35 2028-03-14 Agricultural Sciences Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 SURVEY, SAFETY AND EFFICACY OF HERBAL PRODUCTS USED FOR MALARIA PROPHYLAXIS AND TREATMENT IN UGANDA.
REFNo: HS5468ES

To conduct a survey of herbal medicinal products used for malaria prophylaxis and treatment, evaluate their safety and prophylactic efficacy among school-age children (8-15yrs) in Kibuku district, Uganda.
1. To identify herbal medicinal products used by communities for malaria prophylaxis and treatment in Uganda.
2. To evaluate the artemisinin content of herbal medicinal products used by communities for malaria prophylaxis and treatment in Uganda.
3. To determine the antiplasmodial activity (IC50) of herbal medicinal products used for malaria prophylaxis and treatment in Uganda.
4. To evaluate the safety of herbal medicinal products used for malaria prophylaxis among school age children (8-15 years) in Kibuku district in eastern Uganda.
5. To determine malaria incidence among school age children (8-15 years) receiving selected herbal medicinal products for malaria prophylaxis compared to monthly Dihydroartemisinin-Piperaquine (DP) in Kibuku district in eastern Uganda.
6. To determine prevalence of parasitaemia among school age children (8-15 years) receiving selected herbal medicinal products for malaria prophylaxis compared to monthly Dihydroartemisinin-Piperaquine (DP) in Kibuku in eastern Uganda.

 Uganda 2025-03-14 19:08:33 2028-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
Irene  Vries de
ID: UNCST-2024-R003372
 A pilot Study for introducing a Point of Care Ultrasound (POCUS) device (Baby Checker), supported by Artificial Intelligence (AI), in peri-urban UgandaVersion 1.3 August
REFNo: SS3581ES

Objective and Research Questions
The objective of this research is to assess the technical performance and health outcomes resulting from the introduction of the BabyChecker device in peri-urban Uganda. Specifically, the study aims to evaluate its impact on enhancing timely ANC, including routine care and referrals, thereby potentially reducing maternal and perinatal morbidity and mortality rates. This evaluation will inform developers and implementers on the effective and responsible deployment of the BabyChecker Point-of-Care Ultrasound Scan (POCUS).

2.1 Research Questions per Component
A. Technical Performance
Health Worker performance research questions:
1. What is the initial scanning performance of health workers by cadre on their first day of using BabyChecker?
2. What is the average scanning performance over the study period for health workers by cadre (e.g., certificate, diploma, degree nurses, midwives, clinical officers)?
3. Is there a correlation between the average scanning performance of health workers and their cadre or years of experience?
4. How much time do health workers require to navigate the BabyChecker application and complete a scan on their first day?
5. What is the average time required by health workers to navigate the BabyChecker application and complete a scan over the study period?
6. How well is the BabyChecker equipment maintained throughout the study period?
Artificial Intelligence (AI) research questions:
1. What is the specificity and sensitivity of BabyChecker's AI in estimating gestational age during the first and second trimesters?
2. What is the specificity and sensitivity of BabyChecker's AI in identifying non-cephalic fetal presentation and low placental localization or placenta previa during the third trimester (36+ weeks)?
B. Health Effectiveness
The hypothesis posits that the introduction of BabyChecker will increase ANC attendance during the first trimester and improve access to imaging services, leading to early detection of risk factors and subsequent referrals. The study focuses on observing changes in ANC attendance, risk factor identification, and referral initiation as direct outcomes of the POCUS intervention.
Health Effectiveness of BabyChecker (AI + Remote Read Results) research questions:
1. Does the introduction of the BabyChecker and other VHE community interventions contribute to an increase in pregnant women first attending ANC during the first trimester?
2. Does the introduction of the BabyChecker and mobilization contribute to an increase in pregnant women that come for the 8th ANC visits?
3. Does the introduction of BabyChecker contribute to an increased overall number of ANC visits?
4. Does the introduction of BabyChecker increase the detection rate of pregnancy risk factors such as multiple pregnancies, placenta previa, breech presentation, or non-longitudinal fetal positions?
5. Does the introduction of BabyChecker increase referrals for multiple pregnancies, placenta previa, breech presentation, or non-longitudinal fetal positions?
6. Do women follow through on referrals, and do these referrals lead to improved health outcomes among women in the private sector?

 Netherlands 2025-03-14 18:58:29 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Mugwano
ID: UNCST-2024-R002967
 IMMEDIATE AND LONG TERM OUTCOMES OF PATIENTS WITH SEVERE MITRAL STENOSIS UNDERGOING BALLOON MITRAL VALVULOPLASTY (BVM) AT THE UGANDA HEART INSTITUTE.
REFNo: HS5507ES

1. To describe the immediate (post-operative) outcomes of patients who underwent BMV at UHI during the study period.

2. To describe the long term (1 year and 5 year) outcomes of patients with severe mitral stenosis who underwent BMV at Uganda heart institute during the study period.

Uganda 2025-03-14 18:51:15 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Fiona  Nakabugo Kabuuka
ID: UNCST-2024-R003631
 UTILIZATION AND DETERMINANTS OF HIV TESTING AND COUNSELING SERVICES AMONG YOUTH IN KAWAALA VILLAGE, LUBAGA PARISH, LUBAGA DIVISION
REFNo: HS5339ES

To assess the health-facility determinants influencing the utilization of HIV Testing and Counseling services among youths in Kawaala village, Lubaga Parish, Lubaga Division in May 2024.,To assess the environmental related determinants influencing the utilization of HIV Testing and Counseling services among among youths in Kawaala village, Lubaga Parish, Lubaga Division in May 2024.,To determine the individual determinants influencing the utilization of HIV Testing and Counseling services among youths in Kawaala village, Lubaga Parish, Lubaga Division in May 2024.,To determine the level of utilization of HIV Testing and Counseling services among youths in Kawaala village, Lubaga Parish, Lubaga Division in May 2024.,To assess the utilization and determination of HIV testing and Counseling services youths in Kawaala village, Lubaga Parish, Lubaga Division in Kampala District in May 2024.,
 Uganda 2025-03-14 18:37:36 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Murezi Mereth
ID: UNCST-2023-R007640
 Effects of Lifestyle and Environmental Change on the Human Epigenome
REFNo: HS5243ES

To advance our understanding of the epigenomic mechanisms that mediate the acclimatization to major transitions in lifestyle and environment to understand how populations adapt, both in the past and in the future.
Characterize how extreme lifestyle and environmental transitions affect patterns of gene regulation.

 Uganda 2025-03-14 18:36:41 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 International classification, cancer and care: Accounting for the diagnostic potential of low- and middle-income countries
REFNo: SS3561ES

NOTES: The overall project is guided by three research questions, given here with their related objectives. Specific objectives for research activities in Uganda are also described. RESEARCH OBJECTIVE 1: What are the “on-the-ground realities” of brain tumour diagnosis and care in Sub-Saharan Africa and how does diagnostic practice in brain tumours differ across the region? OBJECTIVE 1: To develop three detailed empirical case studies of diagnostic work and brain tumour care in Uganda, Nigeria and South Africa that are embedded in understandings of care23, national policy, socio-technical infrastructures, and international classification. OBJECTIVE 2: To compare empirical case studies to develop rich understandings of how practitioners in Sub-Saharan Africa use, refuse, or adapt WHO classifications, or mobilise to establish their own terms of reference. OBJECTIVE 3: To generate critical perspectives on diagnostic value, where diagnosis might not be assumed an essential condition of good care. RESEARCH QUESTION 2: How are the diagnostic contexts of LMICs considered by experts writing international cancer classifications? OBJECTIVE 4: To examine how international cancer classifiers understand diagnostic approaches and infrastructures in LMICs. OBJECTIVE 5: To examine the individual values and institutional principles that guide how classifiers consider these approaches in their decision-making about cancer classification. RESEARCH OBJECTIVE 3: How are local medical practitioners, cancer advocates, and international organisations mobilising in a regional network to improve brain tumour outcomes across Sub-Saharan Africa? OBJECTIVE 6: To explore how local medical practitioners, advocates, and international organisations in Sub-Saharan Africa are collaborating in a new professional network, Society for Neuro-Oncology Sub-Saharan Africa (SNOSSA), to improve brain tumour diagnosis and care across Sub-Saharan Africa. OBJECTIVE 7: To examine how members understand unity and diversity among Sub-Saharan African countries, and establish common aspirations and strategies concerning diagnosis and classification. OBJECTIVE 8: To explore how members understand their work on a disease which is considered rare, yet its true incidence unknown, and which is de-prioritised in national and international funding. The specific research objective for research conducted in Uganda is to develop a thorough ethnographic understanding of how brain tumour diagnosis happens in practice; how diagnostic work relates to local sociotechnical infrastructure, national policy, and international classification; and how diagnosis relates to care and treatment decision-making.
 Uganda 2025-03-14 18:29:40 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
ssonko jackson
ID: UNCST-2022-R009683
 SOCIAL SECURITY POLICY IMPLEMENTATION AND CLIENTS' SATISFACTION: A CASE OF NATIONAL SOCIAL SECURITY FUND BENEFICIARIES IN UGANDA .
REFNo: SS2326ES

To investigate the contribution of the Social Security Policy Implementation on NSSF Clients’ Satisfaction in Uganda,To assess the influence of Legal framework for social security on NSSF clients’ satisfaction in Uganda.,To analyze the congruence between of Social Security Policy Implementation andLegal framework for social security with particular reference to NSSF in Uganda,To investigate the contribution of the Social security policy to NSSF clients’ satisfaction. The donation is regarded as mediating the Legal Framework for Community Safety with a particular focus on Kampala and the surrounding areas of Uganda.,
 Uganda 2025-03-14 18:26:08 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
GWOKYALYA EDITH BAAGALA
ID: UNCST-2023-R005596
 Academic staff workload and Quality management in private chartered universities in Uganda
REFNo: SS3509ES

i. To examine the effect of the academic staff workload on total quality management in Private chartered universities in Uganda.
ii. To evaluate the effect of academic staff workload on faculty development programs in private chartered universities in Uganda.
iii. To examine the effect of faculty development programs on total quality management in Private chartered universities in Uganda.
iv. To assess the mediating effect of faculty development programs in the relationship between academic staff workload and total quality management in Private chartered universities in Uganda

 Uganda 2025-03-14 18:24:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Paulous Serugo
ID: UNCST-2023-R005541
 EFFECT OF BIOTECHNOLOGY-GENERATED CROPS ON SOCIALAND ECONOMIC JUSTICE OF SMALLHOLDER FARMERS IN CENTRAL UGANDA
REFNo: SS2560ES

To evaluate the benefits and costs of biotechnology-generated crops on the social justice of smallholder farmers.,To investigate the effect of biotechnology-generated crops on improved food availability for smalljholder farmers,To analyse the effect of biotechnology-genrated crops on the growing and utilization of indigenous crops,To assess the adoption process of biotechnology generated crops among smallholder farmers in cnetral Uganda,Investigate the effect of biotechnology-genrated crops on social and economic justice of smallholder farmers in central Uganda,
 Uganda 2025-03-14 18:22:43 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Brenda Ainomugisha
ID: UNCST-2021-R013462
 EFFECT OF POINT-OF-CARE CONTRACEPTIVE PROVISION ON MODERN METHODS UPTAKE AMONG WOMEN DELIVERING BY CESAREAN SECTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS4718ES

MAIN OBJECTIVE
To describe patterns of immediate postpartum contraceptive uptake, evaluate the effect of point-of-care
provision on uptake, and identify factors influencing uptake among women delivering by cesarean
section at Mbarara Regional Referral Hospital.

SPECIFIC OBJECTIVES
1. To determine the prevalence of immediate postpartum modern contraception uptake among women
delivering by cesarean section at Mbarara Regional Referral Hospital
2. To determine the factors associated with immediate postpartum modern contraception uptake among
women delivering by cesarean section at Mbarara Regional Referral Hospital
3. To evaluate the effect of point-of-care contraceptive provision intervention on immediate postpartum
modern contraceptive uptake among women delivering by cesarean section at Mbarara Regional
Referral Hospital
4. To explore the barriers and facilitators of point-of-care contraceptive provision on immediate
postpartum modern contraceptive uptake among women delivering by cesarean section at Mbarara
Regional Referral Hospital
5. To describe postpartum modern contraceptive uptake among women who experienced the point of care
provision of contraceptive methods up to one year of follow-up
 Uganda 2025-03-14 18:18:20 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Alex Muheesi Gerald
ID: UNCST-2024-R002585
 PUBLIC PROCUREMENT MANAGEMENT PRACTICES AND SERVICE DELIVERY
REFNo: SS3520ES

General objective
To examine the effect of procurement management practices on service delivery by Ugandan Cities
Specific objectives
i. To examine the effect of procurement planning on service delivery
ii. To assess the effect of transparency and accountability on service delivery
iii. To evaluate the effect of competitive bidding on service delivery
iv. To examine the effect of contract management on service delivery
v. To assess the role of leadership and politics on service delivery

Uganda 2025-03-14 18:15:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Musa Sekamatte
ID: UNCST-2024-R016555
 Understanding Multisectoral Collaboration for Strengthening Antimicrobial Resistance Interventions in Uganda.
REFNo: HS5641ES

1. To examine how MSC for strengthening AMR interventions occurs
2. To determine the barriers for facilitators for strengthening MSC of AMR interventions
3. To describe features of a desirable MSC model for strengthening AMR interventions

 Uganda 2025-03-14 18:11:39 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Jessica Lambert Elisabeth
ID: UNCST-2024-R003524
 Tracing the Pathways
REFNo: SS3347ES

 To identify barriers and enablers to successful program implementation, To evaluate the cost-effectiveness of the interventions, To compare the outcomes of different interventions and identify key factors contributing to well-being and self-reliance., To evaluate the current mental health status and self-reliance of former beneficiaries of TPO_Uganda’s programming,
 USA 2025-03-14 18:07:03 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Innocent kemigisha
ID: UNCST-2024-R003156
 EVALUATING THE EFFICACY OF CONTINUOUS PROFESSIONAL DEVELOPMENT PROGRAMMES FOR TRAINERS IN TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING IN UGANDA
REFNo: SIR423ES

iv. Determine professional development needs of TVET trainers in Uganda.,iii. Ascertain the challenges that were met when implementing these programs.,ii. Determine the impact of CPD on TVET trainers in Uganda.,i. Find out the features of the CPD programs that have been conducted for TVET trainers in Uganda.,The research will analyze continuous professional development (CPD) programmes for TVET trainers in Uganda to determine their effectiveness,
 Uganda 2025-03-14 18:05:40 2028-03-14 Engineering and Technology Non-Clinical Trial Degree Award
Richard MIGISHA
ID: UNCST-2024-R002154
 Enhancing Zoonotic One Health Engagement and Communication (ZOHEC) and Non-communicable diseases (NCDs) intervention in selected districts of Southwestern Uganda
REFNo: HS5420ES

To enhance the prevention, detection, and control of zoonotic diseases, diabetes and hypertension by strengthening risk communication, community engagement, surveillance systems, and the capacity of health workers, while fostering collaboration across human, animal, and environmental health sectors,
 Uganda 2025-03-14 18:02:18 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Steven Bulega Elijah
ID: UNCST-2024-R003520
 FACTORS ASSOCIATED WITH IMMEDIATE ADVERSE MATERNAL AND NEONATAL OUTCOMES OF OBSTRUCTED LABOR AT KAYUNGA REGIONAL REFERRAL HOSPITAL IN UGANDA
REFNo: HS5564ES

1. To identify the prevalence of obstructed labor at KRRH among women that delivered there from January to December 2023
2. To assess the factors associated with the immediate adverse maternal and neonatal outcomes of obstructed labor at KRRH among women that delivered there from January 2023 to December 2023
3. To explore the immediate adverse maternal and neonatal outcomes of obstructed labor at KRRH among women that delivered there from January 2023 to December 2023
 Uganda 2025-03-14 18:00:07 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lynn Atuyambe Atuyambe
ID: UNCST-2021-R012602
 Exploring the facilitators and barriers of coverage, access, and use of HPV vaccination services among girls aged 10-14 years in Uganda
REFNo: SS3473ES

4. Determine the overall national performance of HPV vaccination in Uganda,3. Describe Uganda’s overall context of cervical cancer and HPV vaccination in cancer prevention and adolescent health,2. To document the challenges facing the least performing 12 districts, the interventions applied through the World Bank Group grant-funded activities,1. To explore the facilitators and barriers of coverage, access, and use of HPV first and second dose (full dose vaccination) services among girls aged 10-14 years in Uganda ,
 Uganda 2025-03-14 17:53:23 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
 Impact of an outreach program on reduction of pediatric surgical disease in a refugee population
REFNo: HS5568ES

Aim 1: Evaluate the impact of an outreach program on reduction of pediatric surgical disease and averted disability (a) in comparison to a historical cohort (b). Aim 2: Assess acquisition of knowledge and behavior change of refugee settlement healthcare providers in identifying and referring pediatric patients with surgically treatable disease.
Uganda 2025-03-14 17:50:38 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
 Field clinical evaluation of the NG-Test Point of Care lateral flow device (LFD) for monkeypox diagnosis in Uganda
REFNo: HS5602ES

To evaluate detection performance and clinical agreement of Rapid Point of Care (POC) antigen assay for diagnosis of mpox among clinically suspected patients in healthcare facilities in Kampala, Wakiso, Mukono, and Nakasongola districts in Uganda.

Specific objective 1
To determine the diagnostic sensitivity, specificity, & predictive values of the Rapid NG-Test antigen
assay in comparison to PCR and sequencing among patients with mpox
Specific objective 2
To identify MPXV clade (s) circulating among patients with mpox through virologic metagenomic
sequencing

 Uganda 2025-03-14 17:48:15 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOLLY KAKKAYI NYESIGIRE
ID: UNCST-2024-R004296
 TALENT MANAGEMENT PRACTICES AND EMPLOYEE PERFORMANCE IN SELECTED PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS3682ES

The objectives of this study are:
1. To examine the influence of talent attractiveness on employees performance in Public Universities;
2. To investigate the effect of talent motivation on employees performance in Public Universities;
3. To explore the effect of talent development on the performance of employees in Public Universities;
4. To establish the relationship between talent retention and employees performance in Public Universities.
5. To examine the moderation effect of employee commitment on the relationship between talent management practices and employee performance.

Uganda 2025-03-14 17:45:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 A global phase 3, randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in adolescents and adults with sickle cell disease
REFNo: HS5637ES

1. To demonstrate superiority of
treatment with etavopivat
versus placebo in adolescents
and adults with SCD.
2. To evaluate clinical efficacy
measures of etavopivat treatment
versus placebo in adolescents
and adults with SCD
3. To assess clinically meaningful
improvement in fatigue and
functional exercise capacity
and QOL measures of
adolescents and adults with
SCD taking etavopivat
treatment compared to placebo
 Uganda 2025-03-14 17:26:26 2028-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
UMI BUNU OMAR
ID: UNCST-2024-R002604
 ASSESSMENT OF THE IMPACT OF SUBSTANCE OF ABUSE AMONG YOUTH IN BUSHENYI DISTRICT, WESTERN UGANDA.
REFNo: HS5415ES

i) Determining the prevalence and associated factors of substance of abuse among youth in Bushenyi District, Western Uganda.
ii) Assess the patterns of abused substances among the youth in Bushenyi District, Western Uganda.
iii) Determine the impact of substance of abuse on the youth in Bushenyi District, Western Uganda.
iv) Evaluate interventions implemented against abused substances among youth in Bushenyi District, Western Uganda

Kenya 2025-03-14 16:57:28 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Okello
ID: UNCST-2019-R000024
 Understanding the economic impact of universal household hand hygiene in children under five in Uganda
REFNo: HS3181ES

To explore the health inequality impact of providing alcohol-based hand rub to mothers enrolled in the Babygel trial.,To determine the association between catastrophic health expenditure and under-five mortality in Uganda.,To estimate the extent to which handwashing with soap offers financial risk protection from out-of-pocket expenditure for treatment of diarrheal disease in children under five in Uganda. ,The main objective is to assess the benefits of household hand hygiene practices in terms of financial risk protection and reduction of health inequality. Furthermore, we will explore the association between under-five mortality and catastrophic health expenditure.,
 Uganda 2025-03-14 16:38:36 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Nagawa
ID: UNCST-2022-R009705
 EARLY NUTRITIONAL INTERVENTION FOR NUTRITIONALLY AT-RISK INFANTS UNDER 6 MONTHS OF AGE TO REDUCE MALNUTRITION IN THE FIRST YEAR OF LIFE
REFNo: HS3503ES

5. To assess the maternal and health worker perceptions on the integrated intervention package.,4. To assess the effect of an early integrated family intervention program for LBW and undernourished children u6m on growth in the first year of life.,3. To understand the barriers and facilitators to the integration of maternal mental health care and community-based management of malnutrition in infants u6m of age.,2. To assess the prevalence of maternal mental health among caregivers of u6m infants.,1. To determine the factors associated with malnutrition among infants u6m of age and challenges caregivers of LBW and undernourished infants face. ,2. To assess the prevalence of malnutrition among infants u6m and their associations, To assess the effect of an early integrated nutrition intervention for nutritionally at-risk infants u6m of age in reducing malnutrition in the first year of life. ,
 Uganda 2025-03-14 16:37:34 2028-03-14 Medical and Health Sciences Clinical Trial Degree Award
Joseph Mukasa
ID: UNCST-2024-R015786
 Youth with Disabilities in Local Government Development Implementation: Exploring the Inclusivity of Mainstream Livelihoods Programmes in South-Western Uganda
REFNo: SS3674ES

The objectives of the research project are to:
1.Conduct a scoping review on the inclusion of youth with disabilities in mainstream livelihood programmes.
2.Determine the participation of youth with disabilities in the implementation of mainstream livelihood programmes.
3.Investigate the factors influencing the inclusion of youth with disabilities in mainstream livelihood programmes.
4.Explore the role played by Organisations of Persons with Disabilities in promoting the inclusion of youth with disabilities in mainstream livelihood programmes.
5.Propose a framework for practicing disability inclusive youth livelihoods development in local government.

 Uganda 2025-03-10 18:06:19 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
 EFFECT OF VIDEO-BASED PATIENT EDUCATION ON PATIENT ANESTHESIA, ENDOSCOPY LITERACY, AND SHOW-UP FOR THEIR INTENDED PROCEDURES AT KYABIRWA SURGICAL CENTER – JINJA CITY
REFNo: HS4465ES

To evaluate the effect of video-based education on surgical procedure attendance among patients at Kyabirwa Surgical Center ,To evaluate the effect of video-based education on the level of patient knowledge about endoscopy among patients at Kyabirwa Surgical Center,To evaluate the effect of video-based education on the level of patient knowledge about anesthesia among patients at Kyabirwa Surgical Center,To determine the level of patient knowledge about, and uptake of their scheduled procedure after reception of conventional and video-based patient education at Kyabirwa Surgical Center,The goal of this research is to evaluate the effect of video-based education on patient literacy about endoscopy and anesthesia, and surgical procedure attendance (show up) at Kyabirwa Surgical Center, Jinja.,
 Uganda 2025-03-10 18:03:34 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dithan Kiragga
ID: UNCST-2024-R004458
 Project Evaluation Protocol for the ACE-BUNYORO Project, Titled: “Accelerating and Sustaining HIV Epidemic Control and Related Diseases in Hoima (Bunyoro) Region in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)” _{ACE-Bunyoro}.
REFNo: HS5579ES

Evaluation objectives: The evaluation will assess;
a) The extent to which the project achieved its specific objectives as stated in the grant application. b) The relevance of ACE Bunyoro project in i) accelerating and sustaining HIV epidemic control
and strengthening regional, district, and community system capacities to achieve and sustain
HIV epidemic control, as perceived by government, district, health facility and project stakeholders, ii) addressing the health needs of its direct beneficiaries (clients) in Bunyoro region
c) The potential for sustainability of project components, results achieved and other efforts aimed at achieving HIV epidemic control in Bunyoro region.

 Uganda 2025-03-10 18:01:54 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laura Munro Catherine
ID: UNCST-2025-R016668
 Investigating the differences in bark feeding behaviour between two wild chimpanzee communities
REFNo: NS918ES

1. To provide new insights into the potential environmental and social drivers of self- medication behaviour in wild chimpanzees, and specifically examine whether community plays a role
2. To provide further evidence of self-medication behaviour in chimpanzees at BCFS
3. To produce more accurate forest compositional data of BCFS for future research and
conservation purposes
4. To add to the evidence of urinalysis as an effective non-invasive health monitoring
method for wild chimpanzees

 UK 2025-03-10 17:57:11 2028-03-10 Natural Sciences Non-Clinical Trial Degree Award
Mark Buntaine Thomas
ID: UNCST-2024-R015926
 Empowering Local Communities to Oversee Waste Management Services
REFNo: SS3614ES

The open burning of household waste is a major public health challenge throughout the Global South, since it creates a direct route of exposure to concentrated air pollution. One reason why people turn to open burning is that the collection of household waste is unreliable. In the context of our study (Nansana Municipality / Wakiso District), municipal and district governments write contracts with private companies to collect waste from specific neighborhoods, but have trouble overseeing those contracts to ensure that pickup schedules are appropriate and that services are reliable. This prevents residents from using services and creates barriers to meeting national goals of reducing the informal disposal of plastic wastes. We will conduct a randomized experiment where the treatment will involve granting authority for the oversight and monitoring of waste services to zones (LC1s), which are the lowest level jurisdiction in Uganda. Specifically, we will provide training to chairpersons in treated zones about (1) new authority for oversight of contractors, including the ability to recommend dismissal of existing contractors who do not meet their obligations; and (2) new responsibilities for recommending contractors in the case of openings. The control zones will continue to have their waste collection contracts centrally managed by municipal or district authorities. Decentralizing authority for waste management may improve the fit of contracts to local conditions. However, the devolution of oversight authority may also raise risks of inefficiency and decreased professionalism in management. We will build upon a previous project with the Nansana Municipal Government and utilize a vetted data collection protocol for measuring informal waste disposal (Buntaine et al. 2024). We will conduct transects through both treatment and control neighborhoods to document the amount of household waste that is disposed informally. The key outcome targeted in the experiment is a decrease in the informal disposal of household waste. We will specifically evaluate whether decentralizing oversight authority decreases the amount of solid waste that is burned in sample zones. Our project aligns with national priorities to decrease the informal disposal of plastic waste.
 USA 2025-03-10 17:55:47 2028-03-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Okello Eri
ID: UNCST-2024-R016563
 SUPPLY CHAIN MANAGEMENT PRACTICES, MARKETING STRATEGIES AND FINANCIAL PERFORMANCE AMONG CEMENT MANUFACTURERS IN TORORO, UGANDA
REFNo: SS3632ES

i. To determinethe effectof inventory management on financial performance among cement manufacturers in Tororo, Uganda.
ii. To assess the influence of logistics management on financial performance among cement manufacturers in Tororo, Uganda.
iii. To examine theeffectof customer relationship management on financial performance among cement manufacturers in Tororo, Uganda.
iv. To evaluate the effect of supply chain integration on financial performance among cement manufacturers in Tororo, Uganda.
v. To analyze the moderating effect of marketing strategies on the relationship between supply chain management practices and financial performance among cement manufacturers in Tororo, Uganda.

Uganda 2025-03-10 17:53:25 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Evelyn LanyeroGrace
ID: UNCST-2024-R016478
 Factors influencing attrition in online continuous professional development in National Teachers Colleges in Uganda
REFNo: SS3645ES

i. To examine the individual, external and internal factors contributing to attrition in Online Continuous Professional Development programs among lecturers in National Teachers' Colleges in Uganda.
ii. To explore time related challenges that influence attrition in online CPD programs among lecturers in National Teachers' Colleges in Uganda
iii. To identify effective strategies for reducing attrition in online CPD programs among lecturers in National Teachers' Colleges in Uganda

 Uganda 2025-03-10 17:50:17 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Elly Katsigaire Atuhereze
ID: UNCST-2024-R002236
 INSTITUTIONAL CAPACITY AND SUCCESS OF SAVINGS AND CREDIT COOPERATIVE SOCIETIES (SACCOs) IN MBARARA DISTRICT
REFNo: SS3619ES

1. To investigate the institutional capacity functions of SACCOs in Mbarara district
2. To examine the effectiveness of SACCOs in addressing the financial needs of members in Mbarara District.
3. To examine the moderating effect of Non-Banking Financial Policy on institutional capacity and success of SACCOs in Mbarara District

 Uganda 2025-03-10 17:48:51 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Eve Katushabe
ID: UNCST-2023-R006183
 Experiences and Satisfaction of Mothers and Midwives for Intrapartum Care Services in South Western Uganda: A mixed methods study
REFNo: HS5048ES

1. To determine the mothers’ level of satisfaction with intrapartum care services in South western Uganda 2. To identify the factors influencing the mothers’ level of satisfaction with intrapartum care services received in South western Uganda 3. To understand the quality of intrapartum care services provided by the midwives in selected health facilities. 4. To explore mothers’ experiences of intrapartum care services in South western Uganda. 5. To explore midwives’ experiences of providing intrapartum care services in South Western Uganda
 Uganda 2025-03-10 17:35:19 2028-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
EVARIST TURYAHABWA RUTAHWEIRE SILVER
ID: UNCST-2023-R007726
 Estimation of cancer risk due to radionuclides in food and water in Kilembe mines area, Western Uganda
REFNo: NS542ES

1. Determine radionuclide concentrations in samples of soil, pyrite wastes, staple food crops, and surface water in the Kilembe mines area.
2. Measure radon concentration in indoor air of residences.
3. Estimate radionuclide transfer factors to maize crops locally grown in the Kilembe mines area.
4. Model radionuclide transfer to maize crops locally grown in the Kilembe mines area.
5. Measure the heavy metal elements in food crop and water in the Kilembe mines area.

 Uganda 2025-03-10 17:22:53 2028-03-10 Natural Sciences Non-Clinical Trial Degree Award
Moses Okumu
ID: UNCST-2023-R008457
 Twendee (let’s go in Swahili): Digital health technologies to promote the sexual health, resilience, and agency of slum-dwelling youth in Uganda
REFNo: SS3631ES

identify resilience and digital health factors to inform the development of future strengths-based interventions for slum-dwelling youth,understand ecological resilience-based factors associated with sexual health inequities ,
 Uganda 2025-03-10 17:01:24 2028-03-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ddamulira
ID: UNCST-2023-R005533
 Endoscopic Third Ventriculostomy(ETV)+/-Choroid Plexus Cauterization(CPC)in treating Infantile Hydrocephalus: A study to Assess the Success and Failure rates of ETV+/-CPC in Children Under 6 months of Age in Uganda
REFNo: HS5446ES

Primary Objective
To describe the outcomes of ETV±CPC performed as index definitive surgical procedure for children less than 6 months of age with hydrocephalus at CCHU from January 2020 to December 2021
Specific Objectives.
1. To determine the ETV±CPC success and failure rates among hydrocephalus patients who had index ETV±CPC at CCHU at less than 6 months of age.
2. To determine the average time to failure for hydrocephalus patients who had index ETV±CPC at CCHU at less than 6 months of age
3. To determine the clinical and radiological characteristics of patients who had index ETV±CPC at CCHU at less than 6 months of age
4. To determine the factors associated with ETV±CPC success or failure among children with hydrocephalus treated with ETV±CPC as index definitive surgery when less than 6 months of age.

 Uganda 2025-03-10 16:56:18 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geofrey Musinguzi
ID: UNCST-2024-R015961
 Monitoring and Evaluation of the Health Facility-level Implementation of the D-Card Project in Uganda
REFNo: HS5573ES

Main objective
To conduct baseline, mid-term and endline data collection and analysis for D-Card project evaluation on availability, utilization, and quality of care of NCD healthcare delivery in primary healthcare facilities in Uganda.

Specific objectives
1. To assess changes in the availability of medicines, technologies, screening, and treatment services for hypertension and diabetes at baseline, mid-term and endline across selected health facilities.
2. To evaluate the quality of care for hypertension and diabetes at the facility and population levels at baseline, mid-term and endline.
3. To identify challenges and barriers affecting the implementation of D-Card project from the perspectives of health professionals, district managers, and national health
authorities.
4. To assess the impact of the D-Card project on health system performance including service delivery and integration, based on views of key stakeholders.
5. To assess the affordability and accessibility of insulin, including cost per unit, injection frequency, and barriers to procurement, to inform strategies for improving diabetes care.
 Uganda 2025-03-10 16:47:41 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Rose  Nagita
ID: UNCST-2024-R004180
 Perceptions Of Academic Staff On Retention Approaches In Church Founded Higher Education Institutions In Uganda: A Qualitative Study
REFNo: SS2766ES

3. To discover the expectations of academic staff for their retention in Church-founded Universities in Uganda.,2. To analyze the views of academic staff towards the staff retention approaches applied in Church of Uganda founded Universities in Uganda. ,1. To establish the staff retention approaches applied by Church-founded Universities in Uganda.,
 Uganda 2025-03-10 16:28:25 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Hellen Mshilla Mghoi
ID: UNCST-2024-R004481
 Social Integration of Youth Born in Lord's Resistance Army Captivity in Gulu District, Uganda
REFNo: SS3041ES

3. To find out the meanings of the access to social integration resources by YBLC living in Gulu district to youth and their communities.,2. To analyze how YBLC living in selected parishes in Gulu districts in the Acholi sub region of northern Uganda access resources for their social integration.,1. To examine resources needed for the social integration of YBLC living in the Acholi sub region of Uganda access.,The main objective of the study will be to contribute to knowledge on the access to resources for social integration by youth born in LRA captivity (YBLC) in the Acholi sub-region of Northern Uganda. ,
 Kenya 2025-03-10 16:25:49 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Christine Nimwesiga
ID: UNCST-2024-R015680
 AN ACTION PLAN TO IMPROVE COMPLIANCE WITH NURSING AND MIDWIFERY REGULATIONS IN UGANDA
REFNo: HS5554ES

1. To assess the prevalence of compliance to registration and licensing standards of nurses and midwives in Uganda over the past 5 years.
2. To determine the factors associated with nurses' and midwives' compliance to registration and licensure standards in Uganda.
3. To explore the challenges faced by nurses and midwives in complying with the registration and licensure standards in Uganda
4. To develop an action plan to facilitate compliance with registration and licensure standards for nurses and midwives in Uganda.
5. To validate the action plan to facilitate compliance of nurses and midwives with registration and licensure standards.

 Uganda 2025-03-10 16:21:52 2028-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Erick OKEK Jacob
ID: UNCST-2023-R007305
 BURDEN, HUMORAL IMMUNE RESPONSE AND MULTIPLICITY OF PLASMODIUM FALCIPARUM INFECTIONS STRAIN AMONG CHILDREN IN NORTHERN UGANDA
REFNo: HS5306ES

i) Malaria burden in settings (Gulu and Yumbe districts) receiving different combinations of mosquito vector control measures ii) Explore variability of Plasmodium falciparum parasite characteristics in settings (Gulu and Yumbe districts) receiving different combinations of mosquito vector control measures for malaria control
iii) To conduct a systematic reviews and meta-analysis on the effects of age and exposure on development of Naturally acquired immunity against malaria among children in settings receiving different combinations of malaria control measures across Sub-Saharan Africa
 Uganda 2025-03-10 16:20:59 2028-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Bryer
ID: UNCST-2024-R016311
 Social nutrition in guenons in Uganda
REFNo: NS895ES

I will investigate the effects of conspecific sociality on nutritional intake and nutrient balance in two forest guenon species in Uganda. Though we will investigate the nutrition of both sexes, we will start by examining adult female guenon social nutrition. Female guenons may face a tradeoff between (1) competition with conspecifics, potentially in the context of shallow dominance hierarchies, and with other monkey species and (2) their own nutritional goals. I will examine conspecific social behavior and nutrition at Kanyawara site, Kibale National Park, where I will continue my redtail nutrition work (Bryer 2020) examining nutrient intake and balance of female redtails in the context of conspecific and heterospecific feeding competition. I will also examine diet, then nutrition, and social behavior of females in one L’Hoest’s monkey group.
USA 2025-03-10 16:19:38 2028-03-10 Natural Sciences Non-Clinical Trial Non-degree Award
KAJJABWANGU RONALD
ID: UNCST-2024-R003479
 UTILIZATION OF PRECONCEPTION CARE AMONG WOMEN OF REPRODUCTIVE AGE ATTENDING ANTE-NATAL CLINIC SERVICES AT ANYEKE HEALTH CENTER IV, OYAM DISTRICT, NORTHERN UGANDA
REFNo: HS5626ES

To determine the health system factors associated with utilization of preconception services among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District.,To determine the socio Demographic factors associated with utilization of preconception services among women attending ANC services at Anyeke Health Center IV of Oyam District ,To determine the level of knowledge on PCC among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District ,To determine the level of uptake of preconception care services among women age attending ANC services at Anyeke Health Center IV of Oyam District ,To assess the level of Utilization of preconception care among women of reproductive age attending ANC services at Anyeke Health Center IV of Oyam District ,
 Uganda 2025-03-10 16:18:19 2028-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
 Feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting.
REFNo: HS2676ES

Our aim is to explore the feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting. The specific objectives will be:
1. To explore the feasibility of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
2. To explore the safety of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
3. To understand the and acceptability of using the BabySaver Tray and NeoBeat together for neonatal resuscitation in a low resource setting
4. To generate a list of the most robust clinical outcome measures for a future effectiveness evaluation

 Uganda 2025-03-10 16:14:38 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Femke Bannink Mbazzi Bannink
ID: UNCST-2023-R008308
 Disability Inclusive Youth (DIY) research: an innovative and co-creative study to improve inclusion of children and youth with disabilities in health research in East Africa
REFNo: SS3665ES

The aim of this study is to explore barriers and facilitators to the inclusion of children and youth with disabilities in health research, co-create solutions to make health research in East Africa disability disability-inclusive, and create a disability knowledge and research centre to inform and support inclusive health research in the region. In this study, we will use the African Youth’s Charter’s definitions of children (0-18 years) and youth (15-35 years). The study has 3 core objectives: 1) co-creative innovative participatory disability health research with youth with disabilities to understand the barriers and facilitators of inclusion of children and youth with disabilities in health research, 2) co-design solutions to make health research inclusive of children and youth with disabilities, 3) capacity building of research teams, co-production and sharing of knowledge with youth with disabilities
Netherlands 2025-03-10 16:13:24 2028-03-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Betty Akwongo
ID: UNCST-2021-R003759
 BIOACTIVITY AND SAFETY OF MEDICINAL PLANTS USED IN THE MANAGEMENT OF CANDIDIASIS IN PADER DISTRICT, NORTHERN UGANDA
REFNo: NS929ES

Main objective: To document and investigate the efficacy and safety of medicinal plants used for treatment of candidiasis in Pader district.

Specific objectives:
1.Document medicinal plant species used to treat candidiasis in Pader District
2.Determine the antifungal activity of priority plants against Candida albicans, Candida glabrata and Candida tropicalis.
3.Evaluate the acute and subacute toxicity of the most active plant species used for treatment of candidiasis.

 Uganda 2025-03-10 16:12:24 2028-03-10 Natural Sciences Non-Clinical Trial Degree Award
Betty Akwongo
ID: UNCST-2021-R003759
 Inventory of Medicinal and Nutraceutical Plants of West Nile Region for Establishment of Botanical Garden in Muni University, Northern Uganda
REFNo: NS931ES

1. To carry out ethno-botanical survey of medicinal and nutraceutical plants used for management/ treatment of various diseases in West Nile region, Northern Uganda.
2. To document usage of medicinal and nutraceutical plants of West Nile region so as to conserve and preserve the traditional indigenous knowledge
3. To find out the ecology of the medicinal and nutraceutical plants of West Nile region to guide future creation of botanical garden

 Uganda 2025-03-10 13:46:41 2028-03-10 Natural Sciences Non-Clinical Trial Non-degree Award
Okello Ronald
ID: UNCST-2024-R002778
 Board of Governors Outlook and the Educational Performance of Catholic-Founded Schools in Uganda
REFNo: SS3659ES

i) To establish the influence of board independence on the educational performance of Catholic founded Grant Aided Secondary Schools in Uganda.
ii) To determine the influence of board composition on the educational performance of Catholic founded Grant Aided Secondary Schools in Uganda.
iii) To examine the head teacher’s role duality and its influence on the educational performance of Catholic founded Government Aided Secondary Schools in Uganda.

 Uganda 2025-03-10 13:44:32 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Kishaija Noel
ID: UNCST-2024-R004309
 Assessing the impact of climate change on farming systems and livelihoods of smallholder coffee farmers in Southwestern Uganda
REFNo: A551ES

i. To document production systems, livelihood sources, and climate change adaptation practices among smallholder coffee farmers in Southwestern Uganda
ii. To determine how climate change has changed coffee farming systems among smallholder coffee farmers in Southwestern Uganda
iii. To determine the relationship between livelihood components and climate change adaptation strategies among smallholder coffee farmers in Southwestern Uganda
iv. To determine the relationship between gender and climate change adaptation strategies among smallholder coffee farmers in Southwestern Uganda
v. To recommend policy interventions that will enhance the sustainability of smallholder coffee production

 Uganda 2025-03-10 13:29:02 2028-03-10 Agricultural Sciences Non-Clinical Trial Degree Award
Josephine Akellot
ID: UNCST-2024-R016329
 Applying findings from prior mental health training and supervision research in rural Ugandan settings: a transdisciplinary research proposal
REFNo: SS3626ES

1. To explore retrospective and future-looking stakeholders’ perspectives on the scope and complexity of task-shifting training and supervision in mental health care
2. To explore retrospective and future-looking policy voice-over the strategy to follow before, during and after task-shifting training and supervision in mental health care

Uganda 2025-03-10 13:24:40 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Elizabeth Ekirapa
ID: UNCST-2020-R014390
 Opt-AMR: Optimizing Antibiotic Usage to Mitigate AMR
REFNo: HS5547ES

Aim: To develop a metric and evidence use process for improving the management of childhood febrile illness in community settings.

Objectives
1) Investigate associations of QoC in a sample of healthcare facilities (HCFs) with AMR to key antibiotics used for febrile illnesses in children.
2) Assess the risk of AMR development through analysis of genomic traits from samples collected in study sites; determine future risk of resistance development.
3) Use mixed methods to investigate community level health system drivers of ABU and AMR at the district level with particular focus on febrile illnesses.
4) Develop a rapid and recurrent surveillance system of ABU and AMR prevalence and of community voices in districts for evidence-based improvement of health system strategies and policies.
 Uganda 2025-03-10 13:18:54 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jamil Wesigomwe Mohammed
ID: UNCST-2024-R015957
 Understanding Conflicts in the Management of Construction of Public Water Works Projects in Uganda
REFNo: SS3725ES

vi. To develop a robust model for efficient and effective conflict management in construction of public water works projects in Uganda,v. To assess the effectiveness of the existing conflict management approaches in the management of construction of public water works projects in Uganda.,iv. To examine the consequences of administrative conflict in the management of construction of public water works projects in Uganda.,iii. To assess the effect of technical conflict in the management of construction of public water works projects in Uganda.,ii. To evaluate the influence of contractual conflict in the management of construction of public water works projects in Uganda.,i. To determine the effect of behavioural conflict in the management of construction of public water works projects in Uganda.,The main objective is to investigate the sources of conflicts in the management of construction of public water works projects in Uganda and devise effective conflict management strategies. ,
 Uganda 2025-03-10 13:13:56 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 Reducing violence against children and intimate partner violence in Uganda: Feasibility Study of Digital Delivery of the Parenting for Respectability Programme
REFNo: HS5488ES

Overall research objective
The overarching objective of the study is to test the readiness, feasibility, and initial effectiveness of the PfR-App in reducing VAC, IPV, and optimising male engagement in order to lay grounds for a Randomised Controlled Trial (RCT) and eventual wider scale-up of the programme.
The specific objectives are to:
1. Assess users’ and facilitators’ perspectives and experiences, acceptability and satisfaction with the PfR-App functionality across contexts and sub-populations.
2. Use the in-app data collection tool to measure evidence of the initial effectiveness of the app by evaluating at the immediate post-test the effect of the digital intervention on knowledge, attitude and practices in parenting.
3. Compare different population characteristics and different delivery options on parents’ engagement with the App and evidence of initial effectiveness, acceptability, attrition, relevance, engagement, usability, and satisfaction.
4. Test the impact of the design features and content of the PfR-App on initial parental engagement and retention in order to achieve the highest possible fidelity/participation rates in the one month after enrolment and use it to improve the App experience for target users.
5. Test the impact of various factors including the timing, frequency, length and order of sessions, push notifications and in-App survey questions on engagement and response rates in order to implement the most effective strategies to achieve the highest possible engagement and retention rates, including optimising male engagement.


Uganda 2025-03-10 13:12:40 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KEVIN ABER
ID: UNCST-2024-R002518
 Microservice Framework for Research Data Management: A Case of Interdisciplinary Research Project-UPCHAIN
REFNo: SIR465ES

To validate MF-RDM using the RDMS,To implement the Research Data Management System (RDMS) based on the developed MF-RDM framework.,To design a Microservice Framework for Research Data Management (MF-RDM).,To determine data requirements for RDM based on the work package in the UPCHAIN interdisciplinary research project.,To develop a scalable Microservice Framework for Research Data Management (MF-RDM).,
 Uganda 2025-03-10 13:02:30 2028-03-10 Engineering and Technology Non-Clinical Trial Degree Award
Robert Odendi Gideon
ID: UNCST-2024-R002130
 ALCOHOL USE, COGNITIVE FUNCTIONS, AND DEMENTIA SUSCEPTIBILITY AMONG ADOLESCENTS IN IBANDA AND LIRA DISTRICTS, UGANDA
REFNo: HS5517ES

4. To explore the proposed approaches to address adolescent alcohol use in Uganda.,3. To explore the perceptions regarding alcohol use among adolescents in Uganda. ,2. To assess the factors associated with cognitive impairment and risky behavioural patterns among adolescents with alcohol use in selected regions of Uganda,1. To determine the prevalence of cognitive impairment and risky behavioural patterns among adolescents who use alcohol in selected regions of Uganda.,To determine the prevalences and factors associated with cognitive impairment and risky behavioral patterns among adolescents who use alcohol, and explore the perceptions of alcohol use among adolescents, and proposed interventions to address adolescent alcohol use in Uganda,
 Uganda 2025-03-10 12:54:08 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Nkangi
ID: UNCST-2021-R012153
 ASSESSMENT OF VACCINE RESPONSES IN 3D TONSIL CULTURES
REFNo: HS5501ES

1. Assess humoral and cellular responses to vaccines and evaluate the vaccine induced metabolic profiles.
2. Modulate vaccine responsiveness using metabolic and immunologic modulatory compounds.
 Uganda 2025-03-10 12:47:51 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Defining the Risk Factor Cascade in Rheumatic Heart Disease
REFNo: HS5503ES

Aim 1: Identify modifiable risk factors for developing RHD using prospective population case-control methodologies. Aim 2: Determine the independent and joint contributions of multi-level risk factors for RHD among children and adults in Uganda. Aim 3: Establish a biobank of RHD patients' tissue samples for future RHD research studies.
Uganda 2025-03-10 12:29:08 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Schola  Matovu Nakachwa
ID: UNCST-2022-R011040
 Development and Testing of BAJJAJJA: An Intervention to Promote Economic Empowerment and Health of Grandmothers who Provide Primary Care for Grandchildren in Uganda
REFNo: SS3611ES

Main Objective
The study’s objective is to refine and test the feasibility and acceptability of my innovative intervention, BAJJAJJA: Building A Joint Action for JaJJAs which couples an income- generating activity (IGA) with nurse-facilitated group health coaching. This objective is informed by the NIH Stage Model of behavioral intervention development.

Specific Objectives
Aim 1: To refine and adapt the BAJJAJJA intervention through a collaborative and iterative feedback process with a diverse community group of 18 members. In a series of sessions, I will iteratively engage diverse community groups (nurses, local officials, IGA experts, and GMCs) and use cognitive interviewing to gain feedback on the appropriateness of study measures, content, delivery, and intervention format.
Aim 2: To test the feasibility, acceptability, and preliminary efficacy of the BAJJAJJA intervention in improving economic and health outcomes among 24 Ugandan GMCs. Over a 12-month period and at three time points of assessment, I will use a mixed methodology with a quasi-experimental design to collect data that will be examined to assess the feasibility, acceptability, and preliminary efficacy of the intervention on participants’ household income and health outcomes.
Aim 3: To explore the barriers and facilitators to (3a) maintenance of the BAJJAJJA individual intervention benefits (e.g., physical activity level and frequency) and (3b) sustainability of the IGA activities (e.g., grandmothers’ accessing external supports such as community resources) at 6 months post-intervention. Following a mixed methods approach, the 24 GMCs from Aim 2 will be interviewed to further evaluate the long-term maintenance and sustainability of the intervention. Health assessments, interviews, and IGA site visits will be used to explore the intervention outcomes and benefits at 6 months post-intervention.

USA 2025-03-10 12:23:29 2028-03-10 Social Science and Humanities Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Randomized trial to evaluate the efficacy and safety of select therapeutic agents in the treatment of Ebola Disease (TOKOMEZA - Ebola Disease Therapeutics)
REFNo: HS5686ES

This is an open-label, adaptive, randomised platform clinical trial to evaluate the impact of 278 potential treatments on mortality in patients with Ebola Disease
 Uganda 2025-03-07 18:39:19 2028-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Shillah  Kwikiiriza
ID: UNCST-2021-R012682
 Entrepreneurship among rural youth in the Kamuli district, Uganda,
REFNo: A575ES

I. Identify the specific entrepreneurship opportunities available for youth in the Kamuli district
II. Inform YEP of the potential entrepreneurship opportunities for improved and sustained youth livelihoods in Kamuli district.
 Uganda 2025-03-07 18:36:02 2028-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Andrew Kanyike Marvin
ID: UNCST-2020-R014554
 Exploring Fund-Pooling Peer-led Patient Support Groups among Hypertension and Diabetes Mellitus Patients in Public Health Facilities in Uganda.
REFNo: HS5668ES

1. To map out fund-pooling peer-led patient support groups for hypertension and diabetes patients at public health facilities in Uganda.

2. To explore the operational mechanisms faced by fund-pooling peer-led patient support groups for hypertension and diabetes patients at public health facilities in Uganda.

3. To explore the barriers and facilitators to hypertension and diabetes patient involvement in fund-pooling peer-led patient support groups at public health facilities in Uganda.
 Uganda 2025-03-07 18:34:54 2028-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shillah  Kwikiiriza
ID: UNCST-2021-R012682
 Assessment of Vegetable Seed Production and Management Practices in Uganda
REFNo: A566ES

1. Determine and assess the existing seed production and management practices by local seed business owners and small-holder individual seed producers in Uganda.
2. evaluate opportunities and limitations associated with vegetable seed production, management, and marketing within seed sources that are readily available to smallholder vegetable growers in Uganda.

 Uganda 2025-03-07 18:30:46 2028-03-07 Agricultural Sciences Non-Clinical Trial Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF INAVOLISIB IN COMBINATION WITH PHESGO→ VERSUS PLACEBO IN COMBINATION WITH PHESGO→ AS MAINTENANCE THERAPY AFTER FIRST LINE INDUCTION THERAPY IN PARTICIPANTS WITH PIK3CA‑MUTATED HER2‑POSITIVE LOCALLY ADVANCED OR METASTATIC BREAST CANCER (INAVO122)
REFNo: HS5649ES

This study will enrol particpants
Uganda 2025-03-07 18:26:49 2028-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
ADENGO EMMANUEL
ID: UNCST-2024-R016315
 EXPLORING THE FOSTERING OF GENERIC SKILLS AMONGST LEARNERS USING THE COMPETENCE-BASED CURRICULUM IN UGANDA: A CASE STUDY OF IGANGA DISTRICT
REFNo: SS3675ES

This study will be guided by the following research questions
i. How do lower secondary teachers perceive generic skills in the competence-based curriculum in Uganda?
ii. What pedagogical strategies are teachers employing in fostering generic skills using the competence-based curriculum in Uganda?
iii. What are the learners’ experiences in learning generic skills using the competence-based curriculum in Uganda?
 Uganda 2025-03-06 15:52:22 2028-03-06 Social Science and Humanities Non-Clinical Trial Degree Award
DOROTHY ATUHURA
ID: UNCST-2024-R002023
 A Study of the Lived Experiences of African Intersex Lives
REFNo: SS3670ES

1. Generate Indigenous Epistemologies: To cultivate and document local and indigenous knowledge and cultural perspectives surrounding biological variations in sex development.
2. Analyze Sociocultural Lived Experiences: To understand the lived experiences and sociocultural ramifications for individuals born with differences in sex development, highlighting their interactions within societal structures
3. Produce Knowledge and Create Awareness about Harmful Cultural Practices and Traditions: The study aims to document the harmful cultural practices surrounding variations in sex development and to contribute to the deconstruction of harmful stereotypes, stigmas, and cultural practices (including infanticide, exploratory rape and “breast ironing”) that adversely affect the quality of life for individuals with sex development differences
 Uganda 2025-03-06 10:58:58 2028-03-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kemigisha Richardson Maria
ID: UNCST-2024-R016057
 Reconceptualizing Inclusion through the Lived Experiences of Students with Disabilities in Contexts of Forced Displacement: A Comparative Case Study
REFNo: SS3649ES

1. To explore how inclusion is understood and experienced by students with disabilities in contexts of forced displacement, centering their lived experiences and perspectives. 2. Investigate the factors, practices, and policies that promote or hinder inclusion for these students in educational settings. 3. To bridge the gap between theory and practice to inform policies, programming, and discourses on inclusive education among stakeholders at the school, national, and international levels. 4. To contribute to the advancement of accessible, participatory, and transformative learning environments for all students. 5. To inform future educational research, policies, and programming related to inclusion.
USA 2025-03-04 19:32:02 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Rawlance  Ndejjo
ID: UNCST-2022-R010993
 Cities of Youth: Drivers and the gendered impact of climate-induced migration on livelihoods, health and well-being, and system capacity in secondary cities in Uganda
REFNo: HS5619ES

4. To document the impact of youth climate migration on the demand and functional capacities of the health and social system of host communities.,3. To evaluate the impact of climate migration and subsequent livelihood transformations on the physical, mental, and sexual and reproductive health of youth migrants and host communities by gender and age.,2. To investigate how youth climate migration transforms livelihoods in new cities by gender and age, by different types of migrants and hosts,1. To explore the role of climate change in driving youth migration and identify the patterns of migration by gender and age.,To assess the drivers and patterns of climate youth migration and its gendered impact on livelihoods and health of youth migrants and host communities, and the system capacity in secondary cities in Uganda to inform preparedness and response interventions to minimize the negative impact of climate youth migration.,
 Uganda 2025-03-04 19:29:55 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nantale  Ritah
ID: UNCST-2021-R012439
 Reducing newborn deaths by improving intrapartum fetal heart rate monitoring using the Moyo device in a low resource setting
REFNo: HS3196ES

To assess the effect of introducing the MOYO device as a means of continuous intrapartum fetal heart rate monitoring on the detection of abnormal FHR patterns.,To assess the effect of introducing the MOYO device as a means of continuous intrapartum fetal heart rate monitoring on the reduction of intrapartum perinatal mortality.,
 Uganda 2025-03-04 19:19:48 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Leela Channer Winstanley
ID: UNCST-2022-R009457
 The evolution and maintenance of an interspecific mutualism between warthogs and banded mongooses
REFNo: NS927ES

The objectives are to understand: 1) Individual variation in mongoose and warthog cleaning engagement 2) How mongooses and warthogs signal to each other to initiate cleaning interactions 3) How cleaning behaviour is transmitted within and and between groups 4) Why cleaning behaviour is restricted to certain populations
 UK 2025-03-04 19:18:04 2028-03-04 Natural Sciences Non-Clinical Trial Degree Award
Angelina Kakooza-Mwesige
ID: UNCST-2020-R014529
 EVALUATION OF THE IMPACT OF THE THREE TIER INTERVENTIONS FOR DISABILITY IN EARLY CHILDHOOD (IDEC) PROGRAMME IN UGANDA
REFNo: HS5596ES

GENERAL OBJECTIVE

The overall aim of this study is to evaluate the impact of the three-tier IDEC model piloted in the two districts of Mubende and Kassanda in Uganda, with a twofold purpose: (1) to improve intervention design and management and (2) to inform decisions about future investment and scale-up by establishing evidence and impact.

SPECIFIC OBJECTIVES.

Primary objectives
1. To determine the coverage of vision screening at 0-3 months and developmental screening at 9 and 18 months in the study sites.
2. To determine the change in functional abilities in children receiving the Tier 2 intervention.
3. To evaluate effects of the individualised (Tier 3) program at regular intervals (at least every 3 months) on child and family functioning, well-being and participation.
Secondary objectives
1. To determine the change in knowledge and skills in parental/caretaker after the Tier 2 interventions.
2. To determine the change in parental/caretaker level of stress after Tier 2 interventions.
3. To determine the change in parental/caretaker level of stress after Tier 3 interventions.

4. To establish the extent to which children with developmental delay and disability Tier 1 are included in ECD programmes
5. To establish the extent to which children with developmental delay and disability tier 2 are included in ECD programmes. (This could be a compliance or fidelity issue
6. To determine how well (fidelity) the health workers provided the Tier 2 and 3 interventions.
7. To determine compliance with Tier 2 and Tier 3 interventions by the caregivers.
8. To determine family satisfaction with all three tiers of the program, including both children that failed and children who passed the screening assessment (Tier I).
9. To determine the costs and cost-effectiveness of the entire program.
10. To assess the likelihood of continuation
Uganda 2025-03-04 13:40:10 2028-03-04 Medical and Health Sciences Clinical Trial Non-degree Award
Apollo Okello
ID: UNCST-2024-R015725
 DEBT FINANCING, DEBT MANAGEMENT BEHAVIOR AND GROWTH SUSTAINABILITY OF SMALL AND MEDIUM-SIZED ENTERPRISES IN LIRA CITY
REFNo: SS3676ES

1. To examine the relationship between debt financing and growth sustainability;
2. To establish the relationship between debt management behaviour and growth sustainability;
3. To establish the moderating effect of debt literacy on the relationship between debt financing and growth sustainability;
4. To examine the moderating effect of debt literacy on the relationship between debt management behaviour and growth sustainability;
5. To examine the nature of debt financing terms, debt management behaviour, and growth sustainability
 Uganda 2025-03-04 13:32:06 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Optimising dissemination mechanisms for Malaria clinical practice guidelines in the evidence ecosystem. (MARC-SE-MAGIC)
REFNo: HS5591ES

To study different dissemination mechanisms, customized to health care professionals or other end users of clinical practice guidelines.
Uganda 2025-03-04 13:11:00 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kayabula  Alex
ID: UNCST-2023-R005649
 Leaders' Personality, Leadership Styles, and Employee Retention in Selected Universities in Central Uganda
REFNo: SS3673ES

Specific Objectives

1. To examine the relationship between introversion and employee retention in in selected universities in central Uganda.

2. To investigate the influence of extroversion on employee retention in selected universities in central Uganda

3. To explore the impact of democratic leadership style on employee retention in selected universities in central Uganda

4. To assess the combined effect of leaders’ personality and leadership styles on employee retention in selected universities in central Uganda

5. To analyze the moderating role of work environment on the relationship between leaders’ personality, leadership styles, and employee retention in selected universities in central Uganda.

 Uganda 2025-03-04 13:03:54 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Antibiotic Resistance Surveillance and Antimicrobial Stewardship Strengthening in the Karamoja Sub-region (ARSK)
REFNo: HS5566ES

2.2.1 To determine the patterns and prevalence of antimicrobial resistance (AMR) in Napak and Moroto districts of Uganda.
2.2.2 To evaluate the knowledge, attitudes, and practices (KAP) related to antimicrobial resistance (AMR), antibiotic use, and antimicrobial stewardship (AMS) among healthcare workers (HCWs), patients, and their caretakers in Napak and Moroto districts.

 Uganda 2025-03-04 13:01:32 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lorna Atikoro
ID: UNCST-2024-R002527
 Improving diagnostics of Antimicrobial Resistance (AMR) in Sub-Saharan Africa- A multicenter project of the COMBAT AMR in Africa network
REFNo: HS5555ES

. To determine the concordance of the point of care tests NG-Test CTX-M MULTI©, NGTest CARBA 5© and NG Test MCR-1© in the diagnosis of extended spectrum beta
lactamases, carbapenemases and colistin resistant bacteria respectively with conventional
phenotypic culture.
• To determine the 28- day clinical outcomes of patients with multi drug resistant gram negative bacteria.
• To identify the mechanisms leading to inconsistent results between the POCTs and
conventional phenotypic culture.
 Uganda 2025-03-04 12:23:18 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 Orthopaedic trauma, infections and cancer care in Uganda - Disease panorama, management and barriers to care
REFNo: HS5535ES

Investigate complication rates after orthopaedic surgery performed in the study hospitals.,To investigate the proportion of patients with traumatic, infectious and malignant orthopaedic conditions that receive surgical versus non-surgical treatment in the study hospitals,The main objective of the study is to study the management and outcomes of a variety of traumatic, infectious and malignant orthopaedic conditions that are common in secondary and tertiary level hospital settings,To identify current health care gaps in the provision of management of traumatic, infectious and malignant orthopaedic conditions in Uganda. ,To investigate barriers and promoting factors to accessing care for pathological fractures ,Identify rates of complications (revision due to malalignment, infection, technical error) from surgery performed in low-resource settings.,Compare patient functional outcomes if the patient is treated non-surgically, treated surgically within 2 weeks of injury or treated surgically later than 2 weeks after the injury.,
 Sweden 2025-03-04 11:09:42 2028-03-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
 Observational Study to Assess the Incidence of Malaria among Children Living with Sickle Cell Disease in Jinja Regional Referral Hospital Eastern Uganda.
REFNo: HS5583ES

General Objective
To describe the epidemiology of malaria in SCD patients in Uganda.

Specific objectives:
Primary Objective
1. To determine the incidence of malaria cases in SCD patients over a 12-month period.
1. Secondary objectives
2. To determine the incidence of asymptomatic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
3. To determine the incidence of submicroscopic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
4. To determine the severity of malaria in SCD patients, including the prevalence of WHO-defined severe malaria complications such as cerebral malaria, respiratory distress, and severe anemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
5. To determine the frequency of sickle cell disease complications associated with a malaria case.
6. To identify temporal patterns in malaria incidence aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period
7. To examine the risk and protective factors associated with malaria susceptibility and severity among malaria-infected SCD patients using malaria chemoprophylaxis.

Exploratory endpoints:

8. To investigate and determine the parasite molecular diversity among SCD patients attending Jinja Regional Referral Hospital?
9. To examine and determine the antimalarial parasite drug resistance patterns among SCD patients


 Uganda 2025-03-04 10:54:17 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HIRALY ASABAHEBWA
ID: UNCST-2024-R016374
 A QUALITATIVE STUDY EXPLORING THE EXPERIENCES OF UNIVERSITY STUDENTS LIVING WITH HIV AND COMPLETING A UNIVERSITY-LEVEL QUALIFICATION IN KAMPALA, UGANDA
REFNo: SS3684ES

To explore the experiences of newly HIV-diagnosed university students in Kampala, Uganda ,
 Uganda 2025-03-04 10:29:29 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
ISMAHIL ADENIYI ADEKUNLE
ID: UNCST-2024-R002602
 EFFECTS OF ETHYL-ACETATE FRACTION OF Bidens pilosa LEAVES ON TESTES AND PITUITARY GLAND OF MALE MICE EXPOSED TO BISPHENOL A
REFNo: HS5372ES

The purpose of this study is to evaluate the impact of B. pilosa on testicular integrity and the pituitary gland of male mice exposed to BPA.
1.3.1 Specific Objectives
i. To assess the effect of B. Pilosa on spermatogenic metrics of the testes such as sperm motility, sperm count, morphology, agglutination, and vitality using routine and extended semen analysis.
ii. To determine the impact of B. pilosa on serum concentration of follicle-stimulating hormone, testosterone, and luteinizing hormone using enzyme-linked immunosorbent assay (ELISA) following BPA exposure.
iii. To assess the changes in testicular oxidative stress biomarkers (such as CAT, SOD, and GSH) and lipid peroxidation using MDA.
iv. To assess the histology, histochemical, and immunohistochemical changes in the testes and pituitary gland following treatment with B. pilosa in BPA exposure using Masson Trichrome, Periodic Acid Schiff (PAS), Hematoxylin and Eosin (H&E), Caspase 3, antiproliferating cell nuclear antigen (PCNA), Bcl-2, alpha-smooth muscle actin (α-SMA), and Bax.

 Nigeria 2025-03-03 11:40:21 2028-03-03 Medical and Health Sciences Clinical Trial Degree Award
Agapitus Kato Babumba
ID: UNCST-2021-R013866
 Linking infectious disease front-liners control efforts with central public health authorities in the African Great Lakes region (Great-Life) project
REFNo: HS5293ES

Study Objectives: The study objectives and their specific objectives are outlined in A to D below. OBJECTIVE A – CAPACITY BUILDING This objective involves testing the integrated nanopore sequencing capacity (DNA and RNA—single isolates and metagenomics) in the study area. Specific objectives: ● Set -up sampling, sequencing, and simple bioinformatic/epidemiological capacity in Bidibidi Health Centre. ● Set up advanced bioinformatics/ epidemiological capacity at UVRI and cascade it to the study area health facilities ● Build capacity in genomic data interpretation and risk communication in genomic epidemiology. OBJECTIVE B - BIOINFORMATICS, EPIDEMIOLOGY, AND INFRASTRUCTURE This objective involves the testing of standardized laptop analysis and compression of the data generated from nanopore runs, including base calling and standard analysis for use at the frontline health facility (Bidibidi HC III). Following analysis, the analytic data (now the size of kilobytes) can be easily and in real-time shared with stakeholders. Specific objectives: ● Develop a common understanding of the key data analytics and infrastructure needs. ● Set up a project-specific frontline laptop-based data-entering and bioinformatic pipeline. ● Set up a central data portal for storing, aggregating, and sharing raw data and analytic output. ● Provide operational user support to the use-case scenarios and external users ● Support high-throughput computation capacity OBJECTIVE C – TRAINING IN RESEARCH TRANSLATION SKILLS, AND EQUITABLE PARTNERSHIP One of the key elements of this project is to generate data that should be transformed into information that will result in public health actions and social impact in the country. The project will involve key stakeholders from the health facility and local and central governments to meet this goal. The stakeholders will be trained in research data interpretation and utilization. The stakeholders will use the training obtained from this project to develop measures and policies. Specific objectives: ● Conduct training of public health authorities and researchers in public health uptake of genomic epidemiological data ● Determine how obtained data will result in local and national guidelines for individual patient treatment ● Determine how data will influence local, national, and regional public health interventions ● Investigate how cross-border disease outbreaks can be coordinated between national and regional authorities OBJECTIVE D - EPIDEMIOLOGICAL AND GENOMIC INVESTIGATIONS The objectives will be fulfilled by conducting three use cases ● Real-time diagnostic and characterization of diarrheal and persistent malaria cases ● Environmental surveillance for antimicrobial resistance genes in the study area. ● Horizon scanning for pathogens of novel unknown infections of epidemic nature (Disease X identification)
Uganda 2025-02-28 17:30:31 2028-02-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Karim Nanyiri
ID: UNCST-2024-R002952
 Role of Mother Tongue in Learning Productive and Receptive Skills in English language: An Analysis of Perceptions of Stakeholders in Secondary Schools of Bugisu Sub-Region, Eastern Uganda
REFNo: SS3393ES

Objectives of the Study

The study will be guided by the main objective and specific objectives.

Main Objective of the Study

The main objective of the study is to investigate the role of mother tongue in learning productive and receptive skills in English language through the analysis of perceptions of stakeholders in secondary schools of Bugisu sub-region, eastern Uganda.

Specific Objectives of the Study

The study will be conducted with the following specific objectives;

1. To determine the influence of students’ productive skills in mother tongue on the learning of productive skills in English language.
2. To determine the influence of students’ receptive skills in mother tongue on the learning of receptive skills in English language.
3. To explore students’ perception of the role of mother tongue in learning productive skills in English language.
4. To explore students’ perception of the role of mother tongue in learning receptive skills in English language.
5. To explore teachers’ perception of the role of mother tongue in learning productive skills in English language.
6. To explore teachers’ perception of the role of mother tongue in learning receptive skills in English language.
7. To explore the barriers encountered by lower secondary school students in the learning of productive and receptive skills in English language.

Uganda 2025-02-28 16:02:44 2028-02-28 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 Molecular, Serological and Immunological Characterisation of Clade 1b Mpox to Improve Diagnostics for Local and Regional Epidemic Response.
REFNo: NS934ES

1. Genetic and Immunological Characterisation of Mpox Clade 1b: To characterise the genetic profile and immunological responses associated with the Clade 1b Mpox virus circulating in Uganda and neighbouring high-risk regions. This objective seeks to identify the molecular adaptations and immune response profiles associated with the virus's transmission dynamics and its ability to evade immunity, a critical component in understanding the virus’s spread.
2. Establish Molecular Linkage and Epidemiologic Pathways for Targeted
Interventions: To utilise molecular linkage studies to map transmission chains and epidemiologic pathways of Mpox Clade 1b within and across Uganda, the DRC, Burundi, and South Sudan. This objective will pinpoint high-risk transmission clusters and guide targeted public health interventions, particularly in vulnerable communities such as border regions and fishing populations.
3. Correlating Viral Load with Antibody Dynamics in Clade 1b Cases and Contacts:To comprehensively analyse viral load dynamics across multiple body compartments in Mpox-infected individuals and correlate these findings with IgM, IgG and IgA antibody responses, including both binding and neutralising antibodies. This investigation aims to elucidate the predictive value of antibody kinetics in Clade 1b Mpox infections, including in cases with low or undetectable viral loads. By integrating virological and immunological parameters, this study will enhance our
understanding of host-virus interactions, inform diagnostic sensitivity thresholds, and provide critical insights into the immunopathogenesis of Clade 1b Mpox.
4. Optimisation of Diagnostic Tools for Regional Mpox Response: To optimise, and validate advanced diagnostic methods, integrating molecular and serological tools tailored to Mpox Clade 1b. By leveraging UVRI's Mpox sample repository, this objective will enhance the diagnostic accuracy and timeliness essential for immediate outbreak containment, enabling Uganda and partner nations to identify cases and reduce transmission risk rapidly.
5. Facilitate Global Access to Clade 1b Resources for Vaccine and Diagnostic Development: To enhance global Mpox preparedness, this study will share well-characterized Clade 1b specimens with trusted international collaborating research partners, including World Health Organisation (WHO) and United Kingdom Health Security Agency (UKHSA), after putting in place all necessary material transfer agreements ironing outall policicies and legal issues concerning sample sharing.
These specimens will support the development of standardized reference panels for molecular and serological diagnostics, assay comparability, and the establishment of anti-Mpox reference materials to strengthen global surveillance and response efforts.
This objective aims to support global efforts in vaccine development and diagnostic advancements by providing access to Clade 1b isolates, thereby fostering robust Mpox response capacity worldwide and contributing substantially to epidemic containment.
6. Strengthening Regional Preparedness through Strategic Collaboration: To promote a coordinated Mpox surveillance network with neighbouring countries (DRC, Burundi, and South Sudan) for improved outbreak detection, data sharing, and joint response strategies. This objective aligns with regional health security goals and strengthens collaborative frameworks to combat the Mpox epidemic more effectively across East and Central Africa.
 Uganda 2025-02-25 18:19:08 2028-02-25 Natural Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 RE-IMAGINING TB CARE: TRANSFORMING WHEN, WHERE, AND HOW TB SERVICES ARE ACCESSED AND DELIVERED IN UGANDA
REFNo: HS5570ES

Main Objective
1. To evaluate the effectiveness, implementation and cost of an Intervention strategy to improve Tuberculosis community awareness, screening, testing and linkage to care for TB and comorbidities
Specific Objectives
1. Develop a digital and AI-based strategy (intervention strategy) to enhance CHWs capacity to conduct community awareness, screening, testing and linkage to care for TB and other co- morbidities
2. Determine whether an intervention strategy improves awareness, screening, testing, and linkage to care for TB and other comorbidities
3. Evaluate reach, adoption and implementation of the Intervention strategy
4. Evaluate the incremental costs, outcomes, and cost-effectiveness associated with the Intervention strategy as compared to the Standard of care strategy from the health systems and participant perspectives
 Uganda 2025-02-24 12:02:35 2028-02-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jakyoung Lee
ID: UNCST-2024-R016191
 The Evaluation of the Capacity Building for Community Health Workers (CHWs) in Central Region of Uganda
REFNo: HS5548ES

● Assess progress relative to the project plan and suggest improvements in project execution. ● Establish strategies to enhance the quality of health worker training, community health activities, and other related actions. ● Review and adjust performance indicators based on the Project Design Matrix (PDM) and develop new key performance indicators. ● Formulate an exit strategy from a health system strengthening perspective to enhance the project's sustainability and effectiveness
South Korea 2025-02-20 18:53:36 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 COBIHA- A COMMUNITY BASED INTERVENTION AGAINST HARMFUL USE OF ALCOHOL IN A RURAL SETTING: A pilot study around lake Bunyonyi in Kigezi, Uganda
REFNo: HS5521ES

2.To explore reasons for harmful use of alcohol, and perceptions on effective and acceptable ways of reducing this.,1.To conduct a pilot survey to establish the level of harmful use of alcohol and factors associated with the behaviour , to fill the evidence gap on effective community interventions, the current burden of harmful use of alcohol, and community perceptions of the burden of harmful alcohol use in rural Uganda,
 Uganda 2025-02-20 18:51:21 2028-02-20 Medical and Health Sciences Clinical Trial Non-degree Award
Alfred Jatho
ID: UNCST-2021-R011710
 A Focus on Breast Cancer: Decentralizing Breast Cancer Early Detection through addressing barriers to accessing timely and quality care in Uganda and Zambia
REFNo: HS5551ES

How effective is the developed generic breast cancer training package in equipping
Primary and Community Health Workers with knowledge and skills to train, handle and
refer cases of Breast cancer in Arua and Mbarara health regions?
2. How effective is support supervision and mentorship towards improving the quality of
breast cancer services at primary and community health level?
3. What is the level of awareness and practice of breast self-examination by women
attending HFs in Mbarara and Arua health regions?
4. What is the association between breast cancer screening knowledge and practices of
women attending health facilities ?
 Uganda 2025-02-20 18:31:56 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlotte Bednarski Marie
ID: UNCST-2024-R003417
 Transnational networks of care: international NGO management in Iganga, Uganda
REFNo: SS3628ES

PhD pre-dissertation research
 USA 2025-02-20 18:29:52 2028-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
KOBUSIINGYE FLORAH
ID: UNCST-2024-R001996
 A MOBILE TEACHING-LEARNING FRAMEWORK FOR BRIDGING THE AGRICULTURAL EXTENSION GAP IN RESOURCE CONSTRAINED AREAS. A CASE STUDY OF KIGEZI SUB-REGION
REFNo: SIR464ES

Main Objective -To produce a comprehensive teaching-learning framework aimed at reducing the agricultural extension gap in the Kigezi region.

specific objectives
1. To evaluate current agricultural extension frameworks, identifying their strengths and weaknesses.
2. To design a mobile application framework that facilitates access to information, skills, and technology for farmers, extension officers, and other value chain actors.
3. To assess the feasibility and acceptability of the developed mobile agricultural extension application among farmers, extension officers, and other value chain actors.
 Uganda 2025-02-20 18:27:15 2028-02-20 Engineering and Technology Non-Clinical Trial Degree Award
LOIS BAYIGGA
ID: UNCST-2024-R004310
 PRE-CLINICAL TESTING OF FORWARD-ORIENTED GLOBIN-EXPRESSING LENTIVIRAL VECTOR
REFNo: HS5513ES

e) To determine the efficiency of magnetically assisted transduction in gene modified CD34+ cells, isolated from individuals with sickle cell disease or trait, using flow cytometry and real-time polymerase chain reaction (RT-PCR),d) To compare the efficiency of standard transduction to magnetically assisted transduction in CD34+ cells, isolated from individuals with sickle cell disease or trait, using a forward-oriented globin-expressing lentiviral vector using flow cytometry and real-time polymerase chain reaction (RT-PCR),c) To determine the presence of HbS mutation in the CD34 negative cells isolated from cord blood and red blood cell exchange products using hemoglobin electrophoresis.,b) To determine the yield, purity, and viability of CD34+ cells isolated from cord blood and red blood cell exchange products using multicolor flow cytometry ,a) To isolate hematopoietic stem and progenitor cells (CD34+) from cord blood and red blood cell exchange products using immunomagnetic-based method,To determine the efficacy of the forward-oriented globin-expressing lentiviral vector in HSPCs isolated from individuals with sickle cell disease or trait in Uganda,
 Uganda 2025-02-20 18:26:20 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Effect of non-communicable disease multimorbidity on TB treatment outcomes amogn TBHIV co-infected patients in Uganda
REFNo: HS5506ES

a) To determine the prevalence of, and factors associated with multimorbidity among people with TB and HIV
b) To determine the effect of NCD Multimorbidity on TB treatment outcomes among persons co-infected with HIV.

Uganda 2025-02-20 17:58:06 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Okech Apio
ID: UNCST-2022-R011031
 Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5543ES

Primary Objective
1.To estimate the site-specific IR of
P. falciparum infection by rapid
diagnostic test (RDT) testing,
overall and by age group (5-11
years, 12-17 years, 18-60 years)
during the active detection of
infection period.
Secondary objectives
1.To evaluate the agreement
between RDT and thick blood
smear (TBS), and to evaluate the
sensitivity and specificity of RDT
and TBS using quantitative
polymerase chain reaction (qPCR)
as the gold standard for the
identification of P. falciparum
infection, at baseline and at two
and six months after enrolment.
2.To estimate the site-specific IR of
P. falciparum infections detected
by both active and passive
surveillance over the complete follow-up period (0-6 months),
overall and by age group (5-11
years, 12-17 years, 18-60 years).
Uganda 2025-02-20 17:55:11 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RITAH KICONCO
ID: UNCST-2021-R013263
 MOLECULAR CHARACTERIZATION OF ANGIOTENSIN CONVERTING ENZYME GENE POLYMORPHISMS AMONG TYPE 2 DIABETES MELLITUS NEPHROPATHY IN SOUTHWESTERN UGANDA
REFNo: HS5520ES

Objectives:

Main Objective
1. To characterize angiotensin-converting enzyme gene polymorphisms and determine their relationship with the biomarkers of nephropathy and metabolic indicators as well as explore the barriers and motivators to screening for nephropathy among individuals with type 2 diabetes mellitus living in southwestern Uganda.
Specific Objectives
1. To conduct a systematic review on the ACE I/D polymorphisms and the urine albumin-to-creatinine ratio as predictive markers of nephropathy among adult type 2 diabetes mellitus patients.
2. To establish the ACE alleles and genotypes present in the genome of patients with T2D at the MRRH in SW in Uganda.
3. To determine the association between ACE gene polymorphisms and nephropathy biomarkers among T2D patients at the MRRH in SW Uganda.
4. To determine the association between ACE gene polymorphisms and metabolic indicators among T2D patients at the MRRH in SW Uganda.
5. To explore the barriers and motivators to screening for nephropathy as a health-seeking behavior among T2D patients receiving healthcare at the DM clinic in MRRH in SW Uganda.
 Uganda 2025-02-20 17:50:43 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
VINCENT MUBANGIZI
ID: UNCST-2024-R004232
 RAMPS: REDUCING ALCOHOL PROBLEM DRINKING AND MALNUTRITION THROUGH INCOME-GENERATING PEER SUPPORT GROUPS
REFNo: HS5394ES

To document and evaluate the first peer support groups for men with alcohol problem drinking in Isingiro district
 Uganda 2025-02-20 17:49:15 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eva  Laker Odongpiny Agnes
ID: UNCST-2024-R004807
 Lived Experiences of Mixed Groups of Patients on Dolutegravir after Gaining Clinically Significant Weight.
REFNo: HS5195ES

A) Primary objective (Objective 1)
To explore the lived experiences of PLWH who gained weight after starting dolutegravir and whether these experiences vary among different subgroups.
B) Secondary objective (Objective 2)
To examine the sources of information PLWH have on weight gain and how that shapes their
perceptions.
C) Secondary objective (Objective 3)
To explore how the knowledge of the health risks of excessive weight gain and the willingness of patients to take measures to lose weigh
 Uganda 2025-02-20 17:47:39 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Katie Slocombe
ID: UNCST-2024-R016225
 Development of cognition and communication from infancy to late childhood across different societies
REFNo: SS3663ES

The overall objective of this project is to understand the impact of the socio-cultural environment on the development of communication and social cognition and the developmental processes that lead to similarities and differences in adult human behaviour across the globe. The specific objectives are to address the three research questions below with the Ugandan sample: 1. To understand how aspects of physical, emotional and social cognition, and communication develop from infancy through childhood into adult-like forms within in a rural population of Uganda 2. To understand the socio-cultural context that the participants are developing in. 3. Does individual variation in socio-cultural environmental factors predict individual variation in performance in social cognition tasks?
UK 2025-02-20 17:46:27 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 Understanding barriers and Strengthening Services for HPV vaccination among adolescents living with HIV in Kampala Metropolitan.
REFNo: HS5254ES

4. To document lessons and experiences drawn from piloting outreach HPV vaccine services at Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,3. To pilot HPV vaccination outreach service and education for adolescents living with HIV and attending HIV care and treatment at the Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,2. To determine the knowledge, attitude and practices that influence HPV vaccine uptake among adolescents living with HIV and attending HIV care at Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg). ,1. To estimate the HPV vaccine coverage among adolescents living with HIV attending Joint Clinical Research Centre (JCRC) and Mildmay Uganda (MUg).,
 Kenya 2025-02-20 17:45:09 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Baker Lukwago
ID: UNCST-2021-R013259
 Implementation Study: Introducing a Point of Care Ultrasound (POCUS) Device (Baby Checker), Supported by Artificial Intelligence (AI), in peri-urban Uganda. An Acceptability Study with Providers, Consumers, and Decision Makers September 2024_Version
REFNo: SS3496ES

1.2 Main objective of the research
This research aims to understand the feasibility of implementation of the BabyChecker Ultrasound scan in private health facilities in Uganda. The research will assess the BabyChecker pilot from the perspective of providers, pregnant women, and key decision makers. Among providers, the study will investigate providers’ behaviors and challenges during 1st month of using the tool and shift or maintenance of these behaviors, practices, and challenges after 5 months of implementation attributed to the project interventions. The study will explore pregnant women’s experiences with the BABYCHECKER & preferences for the BabyChecker features. Among decision-makers, the study will explore potential use cases for BabyChecker in Uganda, including the potential for public sector expansion, public private partnership, and private sector referral mechanisms.

The specific aims are as follows:
A: What are experiences, perceptions, barriers and attitudes towards BabyChecker Scan among providers using it?
1. What are the providers' practices on how they conduct the BabyChecker scans and how the tool is positioned to the consumer?
2. How are providers integrating BabyChecker into ANC service provision?
3. What are the motivators & barriers providers are experiencing with the BabyChecker tool and implementation?
4. How much are the providers willing to pay to purchase the BabyChecker scan, and what payment modalities are acceptable?
B: What are the pregnant womens experiences and acceptability of the BABYCHECKER scans among pregnant women receiving them?
1. How was Babychecker introducted to pregnant women offered the service? (What did pregnant women understand regarding the purpose of BabyChecker? Did providers respond to questions raised during the introduction of BabyChecker?)
2. What is the experience of pregnant women during the administration and in the reception of results ofthe BabyChecker scan after 24 hours?
3. What are pregnant women’s stated preferences regarding BabyChecker product attributes?
4. What is pregnant women’s willingness to pay for BabyChecker services?
5. What are pregnant women’s willing to pay for preferred BabyChecker features?
C: What is the acceptability of the BabyChecker technology among Decision makers in Uganda?
1. What are the perceptions of key stakeholders about the BabyChecker Scan and recommended use cases for Uganda? What are their barriers and motivators to scaling BabyCheckers further in Uganda?


 Uganda 2025-02-20 17:43:29 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Twalib Aliku Olega
ID: UNCST-2019-R000474
 LEVERAGING RHEUMATIC HEART DISEASE SCREENING PROGRAMS TO IMPROVE OUTCOMES FOR CONGENITAL HEART DISEASE IN NORTHERN UGANDA
REFNo: HS5492ES

1) To improve the quality of life for families living with CHD in Uganda. Our overarching hypothesis is that building a system centered on the needs of patients and providers at the community level will improve care and quality of life for many while simultaneously building the case to invest in more resource intensive tertiary infrastructure.
Our project leverages our team’s expertise and established government and community collaborations to improve CHD care by accomplishing following specific aim as the first step to delivering and testing an evidence-based primary Health Center (HC) driven program - Congenital Heart Interventions for Primary care Systems (CHIPS) - to care for children with CHD incidentally identified through RHD screening.

2) Identify needs, gaps, and capacities in CHD care to co-design the CHIPS technical package with end-users (patients, caregivers and community providers) by collecting quantitative and qualitative data on current care, care needs, access, and affordability and perspectives on proposed components of CHIPS to co-design content and delivery.
 Uganda 2025-02-20 17:26:59 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Developing and Testing a Package of Interventions to Improve Patient Engagement in Rheumatic Heart Disease Care in Northern Uganda: A mixed Methods Study
REFNo: HS5605ES

Objective 1: To describe the treatment cascade of RHD care in Kitgum district and determine the associated factors.
Objective 2: To explore the barriers and facilitators of patient engagement in RHD care in Kitgum district.
Objective 3: To co-develop a package of interventions to improve patient engagement in RHD care.
Objective 4: To evaluate the effectiveness of a package of interventions to improve patient engagement in RHD care in Kitgum district.
 Uganda 2025-02-20 17:21:09 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 WOMEN’S INCLUSIVE SERVICES FOR HEALTH ACCESS TO QUALITY HEALTHCARE FOR PREGNANT AND BREASTFEEDING WOMEN WITH DISABILITIES IN UGANDA
REFNo: HS5552ES

1. To identify and understand the existing disparities in HIV and maternal healthcare services affecting pregnant and breastfeeding mothers with disabilities
2. To elicit the perceptions and experiences of people with disabilities that affect their health-seeking behavior, especially for HIV, maternal, and reproductive health services.
3. To promote awareness and education among women about their healthcare rights and available services.
4. To collaborate with relevant stakeholders, including healthcare providers, policymakers, and community organizations, to implement sustainable changes.


 UK 2025-02-20 17:18:32 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PRECIOUS NATUHWERA
ID: UNCST-2024-R003154
 Clinical presentations, prevalence and factors associated with cranial hemorrhages among neonates admitted at Mbarara Regional Referral Hospital
REFNo: HS5377ES

General objective
To determine the clinical presentations, prevalence and factors associated with cranial haemorrhages among neonates admitted at Mbarara Regional Referral Hospital.
Specific objectives
1.To determine the prevalence of extracranial and intracranial haemorrhages among neonates admitted to the NICU of Mbarara RRH.
2.To describe the clinical profiles of neonates with cranial haemorrhages admitted to the NICU at Mbarara RRH
3.To determine the factors associated with cranial haemorrhages among neonates admitted to the NICU at Mbarara RRH.

 Uganda 2025-02-20 17:16:30 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Ashirafu  kule masudi
ID: UNCST-2024-R004729
 TEACHER’S COMMITMENT AND STUDENTS’ ACADEMIC PERFORMANCE IN PUBLIC SECONDARY SCHOOLS IN KASESE DISTRICT, UGANDA
REFNo: SS3529ES

i. Examine the relationship between teachers’ job satisfaction and students’ academic performance in public secondary schools in Kasese District, Uganda.
ii. To determine the relationship between work environment and students’ academic performance in public secondary schools in Kasese District, Uganda.
iii. Establish the relationship between teacher’s level of professional training and development on students’ academic performance in public secondary schools in Kasese District, Uganda
iv. Evaluate the relationship between school leadership and students’ academic performance in public secondary schools in Kasese District, Uganda.

 Uganda 2025-02-20 17:15:03 2028-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Naomi Nsubuga
ID: UNCST-2024-R003628
 School Eye Health Rapid Assessment (SEHRA) to review the policy environment and determine the magnitude and patterns of eye health conditions among public primary school children in select regions in Uganda.
REFNo: HS4803ES

2. To determine the magnitude, characteristics and any patterns of eye health conditions among children in selected public primary schools across the six selected regions in Uganda.,1. To conduct a rapid review of the policy, strategy, institutional and service delivery environment for a school eye health programme in Uganda. ,To review the policy environment on school eye health and determine the magnitude and patterns of eye health conditions among public primary school children in selected regions in Uganda,
 Uganda 2025-02-20 17:12:48 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Byarugaba
ID: UNCST-2024-R004225
 Midterm evaluation of Our Rights, Our Future PLUS (O3PLUS)
REFNo: SS2565ES

The evaluation objectives are to:
1. Ascertain the relevance, coherence, effectiveness, efficiency, and sustainability of the O3PLUS Project.
2. Assess progress against targets set at baseline, validate, and populate the results framework.
3. Identify opportunities, challenges, innovative practices, and lessons that will be useful for strengthening and enhancing the implementation of the remaining project period.
4. Provide conclusions and actionable recommendations to shape future programming and implementation of similar initiatives.

Uganda 2025-02-20 17:11:11 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Muhumuza
ID: UNCST-2023-R008646
 Improving Family Wellness for Couples in Central Uganda 2024-2029
REFNo: HS5523ES

The study aims are to:

(1) In a cluster randomised trial, compare the efficacy of the FH=FW intervention vs. a time/attention matched comparator intervention at increasing modern contraceptive use and reducing unintended pregnancy among couples with an unmet need for family planning through 24-months, and identify potential mediators of the intervention effect.

(2) Determine the intervention’s effect on, and determinants of, contraceptive continuation.

(3) Through a mixed-methods process evaluation, explore factors affecting the implementation of the intervention in order to improve feasibility, acceptability, and the likelihood of future adoption and sustainment
 Uganda 2025-02-20 17:09:28 2028-02-20 Medical and Health Sciences Clinical Trial Non-degree Award
Sally Andersson Lova Sofia
ID: UNCST-2024-R002577
 Agrarian Governmentality & Interacting Policies: Young Farmers' Subjectivity and Agency in the Gulu District, Uganda
REFNo: SS3634ES

To gain knowledge on how young farmers in Uganda socially navigate the subjectivities constructed in the policies, using their agency to internalise, adopt, or adapt them, or to create counter-conduct subjectivities. ,To understand how young farmers experience challenges and opportunities in farming, and how they view the solutions to these challenges offered in various interacting agrarian policies. ,To explore the various subjectivities for young farmers found within problem representations in the governmental policies, illuminating possible synergies and discords between policies attempting to solve different challenges, as subjectivities offer different possible courses of actions to young farmers.,To explore how young farmers in Uganda interact with synergies and discords in governmental policy responses to climate change and the associated challenges and opportunities facing young farmers. ,
 Sweden 2025-02-14 17:37:37 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 ConfiSign HIV Self-Test: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS5545ES

The objective of this study is to evaluate the clinical performance and the usability of the ConfiSign HIV Self-Test in the hands of untrained users from a low prevalence HIV region and having no experience in HIV self-testing (HIVST).
The following specific studies will be conducted:
Part 1: Results Interpretation Study
Part 2: Observed untrained user study

 Uganda 2025-02-14 17:33:35 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Asiimwe
ID: UNCST-2019-R000059
 Clinical Spectrum and Societal Impact of Cognitive Impairment, Alzheimer’s and Related Dementias Among People with HIV in Uganda
REFNo: HS5493ES

1. Determine the prevalence and classification of MCI/ADRDs (1A) and compare trajectories of cognitive performance (1B) between older PWH in Uganda and demographically similar HIV-negative individuals.
2. Identify pathophysiologic contributors to MCI/ADRDs in older adults in Uganda by performing deep phenotyping with novel plasma biomarkers and neuroimaging.
3.Discover and validate novel, multilevel mechanistic models of MCI/ADRDs among older PWH by employing ML methods.
 Uganda 2025-02-14 17:30:42 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laura Keihäs Anna Maria
ID: UNCST-2024-R015717
 Exploring the Role of Expressive Arts in the Emancipation and Well-being of Girls. Case Study from Kabale, Uganda
REFNo: SS3612ES

- to gather new information on the relationship between expressive arts, emancipation and well-being of youth, especially Ugandan girls in vulnerable life situations
- to gain a better understanding of the Ugandan and African approaches to well-being and emancipation
- to get new decolonial, Ugandan and African perspectives on global youth research and critical social pedagogy
The study aims to contribute to planetary social pedagogy and global youth research. It will provide new insights and African perspectives on the potential of creative expression to support youth well-being in Uganda and beyond.
 Finland 2025-02-14 17:24:47 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Mugisha
ID: UNCST-2024-R002496
 VICARIOUS TRAUMA AND JOB PERFORMANCE OF WORKERS IN SELECTED HUMANITARIAN ORGANIZATIONS IN SOUTH WESTERN UGANDA
REFNo: SS3592ES

1. To examine the effects of emotional distress on job performance of workers in humanitarian
organizations of Southwest Uganda.
2. To explore effects intrusive thoughts on job performance of workers within humanitarian
organizations of Southwest Uganda
3. To investigate the moderating effects of social support on job performance of workers in
humanitarian organizations of Southwest Uganda.
4. To analyze the moderating effects of self-esteem and gender on the relationship between vicarious
trauma and job performance of workers in humanitarian organizations of Southwest Uganda.
5. To establish the relationship between vicarious trauma and job performance of workers in
humanitarian organizations of Southwestern Uganda
 Uganda 2025-02-14 17:21:36 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Mark Jordans
ID: UNCST-2020-R014861
 POPULATION-LEVEL EVALUATION OF A MENTAL HEALTH CARE PACKAGE FOR CHILDREN IN SELECTED REFUGEE SETTLEMENTS IN UGANDA (PAMOJA TUNAWEZA): A CLUSTER RANDOMIZED CONTROLLED TRIAL (cRCT)
REFNo: SS3571ES

To evaluate the impact of a mental health care system on improving population level mental health of children in refugee settlements, with the following guiding research questions and hypotheses:
 Netherlands 2025-02-14 16:25:24 2028-02-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Diana Namuddu
ID: UNCST-2024-R003660
 Knowledge, attitudes, and practices of healthcare workers regarding the use of standard malaria management guidelines
REFNo: HS5458ES

1) To explore healthcare workers’ knowledge, attitudes, and practices regarding malaria management guidelines in Adjumani and Kitgum districts. 2) To investigate the behavioural and social factors influencing malaria case management among healthcare workers in Adjumani and Kitgum districts. 3) To evaluate healthcare workers' willingness to recommend the malaria vaccine for preventing malaria in children once it becomes available in Adjumani and Kitgum districts. 4) To identify facilitators and barriers affecting the adoption of malaria management guidelines among health workers in Adjumani and Kitgum districts
 Uganda 2025-02-14 16:17:09 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nerima
ID: UNCST-2024-R015736
 A QUALITATIVE STUDY EXPLORING FACTORS AFFECTING MULTIPLE MICRONUTRIENT SUPPLEMENTS (MMS) ADHERENCE AMONG PREGNANT WOMEN IN SOUTH CENTRAL AND BUSOGA REGION IN EASTERN UGANDA.
REFNo: HS5478ES

4. To make recommendations to public health stakeholders and decision-makers on strategies to enhance the uptake of MMS among pregnancy women in Uganda in the context of south and central Uganda.,3. Employ thematic analysis to examine healthcare providers\' perspectives on barriers and facilitators to pregnant women\'s adherence to MMS, as well as their insights into the strengths and weaknesses of existing strategies aimed at improving adherence.,2. Explore, through semi-structured interviews, the perspectives of healthcare providers in Uganda on factors influencing pregnant women\'s adherence to MMS, including their insights into the effectiveness and compliance of existing strategies, policies, interventions, and approaches.,1. 1. To explore existing knowledge on factors influencing pregnant women\'s adherence to multiple micronutrient supplementation.,
 Uganda 2025-02-14 16:15:37 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
kamya Damiano Damiano
ID: UNCST-2024-R002433
 "REMOTELY TEACHING CHILDREN WITH NEURODEVELOPMENTAL PROBLEMS: EXPERIENCES OF TEACHERS, SCHOOL MANAGERS AND PARENTS IN CENTRAL UGANDA"
REFNo: SS3556ES

Purpose of the Study.
The purpose of this study is to explore teachers’, school managers’ and parents’ experiences in remotely teaching children with neurodevelopmental problems in Central Uganda.
Specific Objectives
1. To examine,
a) teachers’
b) school managers’
c) and parents’ experiences on remotely taught children with neurodevelopmental problems.
2. To evaluate the opportunities of remotely teaching children with neurodevelopmental problems.
3. To examine the challenges faced by;
a) teachers
b) school managers
c) parents while remotely teaching children with neurodevelopmental problems.
4. To examine the interventions that can enhance experiences of remote teaching of children with neurodevelopmental problems.

 Uganda 2025-02-14 16:10:11 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Gal Badihi
ID: UNCST-2024-R016596
 Sociality and communication dynamics in grey-cheeked mangabeys (Lophocebus albigena) in the Bugoma Forest Reserve, Uganda
REFNo: NS911ES

The project aims to describe the communicative repertoire and social function of communication in grey-cheeked mangabeys
 UK 2025-02-14 16:05:25 2028-02-14 Natural Sciences Non-Clinical Trial Non-degree Award
SAMSON OKUNG
ID: UNCST-2024-R003644
 COMPETENCE-BASED TRAINING OF AUTOMOTIVE STUDENTS IN TECHNICAL TRAINING INSTITUTES IN THE EASTERN REGION OF UGANDA
REFNo: SIR434ES

(iv) To assess the financial adequacy on competence-based training of Automotive students in Uganda. , (iii) To establish the influence of human resource capacity on competence-based training of Automotive students in Uganda. ,(ii) To examine infrastructure relevance on competence-based training of Automotive students in Uganda.,(i) To determine the influence of instructional resources on competence-based training of Automotive students in Uganda.,The main objective is to investigate the effectiveness of competence-based training of automotive students in technical training institutes in the eastern region of Uganda.,
 Uganda 2025-02-14 15:56:43 2028-02-14 Engineering and Technology Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Evaluation of the Safety, Efficacy and Stability of SangaSupa®-30% Emulsifiable Concentrate [EC]: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricide Field Trial
REFNo: NS910ES

General objectives
To determine the efficacy, safety, and stability of SangaSupa® (Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control.
Specific objectives
The specific objectives of this acaricide field trial will to determine;-
i. efficacy of SangaSupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
ii. safety of Sangasupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
iii. Stability of Sangasupa® when applied onto cattle by plunge dipping for tick control.
Uganda 2025-02-14 15:53:01 2028-02-14 Natural Sciences Clinical Trial Non-degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 A Qualitative Study on Challenges and Opportunities for Non-Surgeons in Providing Inguinal Hernia Surgery in Uganda
REFNo: HS5363ES

To identify facilitators for non-surgeons in providing inguinal hernia surgery in Uganda.,To identify barriers for non-surgeons in providing inguinal hernia surgery in Uganda.,To identify existing barriers and facilitators in implementing task sharing for inguinal hernia surgery by non-surgeons and to explore potential strategies for enhancing surgical care delivery through task sharing in Uganda,To propose recommendations to further strengthen the quality of surgical task sharing in inguinal hernia repair in Uganda. ,
 Sweden 2025-02-14 15:48:55 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
sharot kintu
ID: UNCST-2024-R016314
 CARING FOR CHILDREN WITH SICKLE CELL DISEASE: A QUALITATIVE STUDY OF PARENTS/CAREGIVERS’ EXPERIENCES IN WAKISO DISTRICT
REFNo: SS3536ES

The study seeks to achieve four primary aims/objectives: 1.To understand and document the experiences of parents/carers in looking after children with SCD in Wakiso District. 2.To assess the ways in which the social cultural context in Wakiso affects the ability of the parents to care for children with SCD. 3.To explore the care related needs of the parents that can help them improve their role performance. 4.To identify SCD related with Gender Based violence against caregivers/parents in the community
Uganda 2025-02-14 15:44:16 2028-02-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Byamukama James Adonia
ID: UNCST-2024-R016133
 Assessing the Distribution of Biological Indicators Along Altitude Gradient for Ecological Health of River Ishasha, western Uganda
REFNo: NS886ES

i) To document the anthropogenic activities along the altitude gradient of River Ishasha
ii) To determine selected physicochemical parameter along altitude gradient of River Ishasha
iii) To determine the distribution of periphytons and macro-invertebrates along altitude gradient of River Ishasha
 Uganda 2025-02-14 15:36:06 2028-02-14 Natural Sciences Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Exploring gendered pathways to strengthen the involvement of TB survivors in the Uganda TB response: A Photovoice Study
REFNo: HS5241ES

General objective The aim of this study is to identify gendered pathways for strengthening the involvement of TB survivors, including from key populations1, in the TB response by documenting opportunities, challenges, and preferences to meaningful engagement from the perspective of female and male TB survivors in urban Central Uganda region. Specific objectives The specific objectives of this study are: Objective 1: To use photovoice as a platform for female and male TB survivors to visualise/document their contributions towards ending TB in their families and communities in urban Central Uganda (Q1). Objective 2: To engage female and male TB survivors in photovoice to explore the challenges they face in their efforts to end TB in their families and communities in urban Central Uganda (Q2). Objective 3: To use photovoice as a vehicle for female and male TB survivors to document their preferences for their meaningful involvement in the TB response in urban Central Uganda (Q3-4). Objective 4: To facilitate dialogue between photovoice participants and TB survivors on the photo stories to identify steps towards creating a gender-responsive supportive environment for TB survivors’ actions towards ending TB in Central Uganda (Q5-6). Objective 5: To assess the benefits and challenges of applying photovoice methodology to identify and promote gendered pathways for the meaningful involvement of TB survivors (Q7).
 Uganda 2025-02-14 15:34:56 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayomide Atoki Victor
ID: UNCST-2022-R008808
 BIOMEDICAL EVALUATION OF HESPERIDIN AND NARINGENIN ON NEUROLOGICAL INDICES IN DROSOPHILA MELANOGASTER MODEL OF ALZHEIMER’S DISEASE
REFNo: HS3813ES

Assess the expression of genes relevant to neuronal function in flavonoid-treated flies,Evaluate quantitatively the level of amyloid precursor protein in the flies,Determine the influence of Hesperidin and Naringenin on in vivo antioxidant status in the flies,Assess the effect of Hesperidin and Naringenin on activities of critical enzymes relevant to Alzheimer’s disease in the flies ,Evaluate the effect of Hesperidin and Naringenin on geotaxis, memory and life span in both wild (Harwich strain) and transgenic (Bloomington stock P{UAS-APP695-N-MYC}, P{UAS:BACE1}) Drosophila melanogaster,The main objective of the study is to assess the effect of Hesperidin and Naringenin on biomarkers of neurodegeneration in transgenic D. melanogaster model of Alzheimer’s disease.,
 Nigeria 2025-02-14 15:22:49 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Reducing hazardous alcohol use and optimizing treatment as prevention among men living with HIV in risk environments
REFNo: HS5558ES

Understand barriers and facilitators in the inner and outer context for implementing the components of Kisoboka within the routine clinical setting to inform future widespread implementation guided by the Exploration, Preparation, Implementation and Sustainment (EPIS) framework and documentation of intervention and implementation costs. ,Assess the impact of the Kisoboka intervention and its components on measures of psychological, physical, and socioeconomic well-being that capture frequent comorbidities of people living with HIV and are associated with achieving successful treatment as prevention,Determine the efficacy of the Kisoboka intervention and its components on alcohol and HIV outcomes among hazardously drinking men living with HIV in Uganda in a 2x2 factorial RCT. ,Assess the efficacy of Kisoboka and its components (BE & MI) to gain insight into Kisoboka’s potential effect, determine if BE and MI interact and examine barriers and facilitators for implementing Kisoboka within routine clinical settings to inform future widespread implementation.,
 Uganda 2025-02-14 15:19:41 2028-02-14 Medical and Health Sciences Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 A Prospective, Clinical Trial Examining the Immune Response of Participants Receiving Modified Vaccinia Ankara (MVA) Vaccine in Africa,”-Mpox Vax Africa
REFNo: HS5575ES

To determine:

the development of MVA-BN-specific antibodies at week 6 post-first vaccination with MVA-BN in
a population recruited in Africa, and compare to a population recruited in Europe.

Durability of MVA-BN-specific antibodies at week 24 post-first vaccination with MVA-BN.
● Factors associated with MVA-BN-specific antibody responses at week 48 post-first
vaccination with MVA-BN.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination between a
population recruited in Africa and a population recruited in Europe.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination with MVA-BN in
understudied populations (women and PLWH).
● Prevalence of asymptomatic seroconversion to mpox by week 48 post-first vaccination
 Uganda 2025-02-08 13:35:10 2028-02-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 THE SECOND UGANDA TB PREVALENCE SURVEY (TBPS2)
REFNo: HS5269ES

Estimating the sizes of key and vulnerable TB populations as defined in the national gender and key and vulnerable populations assessment report nationally and sub nationally,Evaluating factors associated with TB including HIV, diabetes, undernutrition, tobacco smoking, alcohol ab use, and socio-economic status,,Updating population-based estimates of TB burden using results from the prevalence survey ,Assessing healthcare-seeking behaviors and understand where individuals with TB symptoms seek medical care,The secondary objectives of TBPS2 in Uganda encompass: The prevalence of symptoms suggestive of pulmonary tuberculosis (PTB) and determining radiological abnormalities among individuals aged ≥15 years, ,The primary objective is to determine the national and subnational prevalence of bacteriologically confirmed pulmonary TB among the general population aged ≥15 years,The goal of the survey is to enable the country (MOH/NTLP and partners) to gain a better understanding of the current burden of TB, health-seeking behavior and health system response in order to identify ways of improving TB programming towards ending TB in the country.,
 Uganda 2025-02-07 18:27:07 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DANIEL KIIZA
ID: UNCST-2024-R004044
 Retrospective chart review of patients with Laboratory-Confirmed Sudan Virus Disease Hospitalized in Two Ebola Disease Treatment Units in Uganda (September 2022 to January 2023)
REFNo: HS5541ES

To evaluate the safety and clinical course of patients receiving investigational treatments for SVD,To identify host and disease factors associated with outcomes from SVD,To characterize the natural history and outcomes of Sudan virus disease (SVD) among hospitalized patients with RT-PCR detected Orthoebolavirus sudanense (SUDV) RNA,
 Uganda 2025-02-07 18:10:59 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 AN OUTCOME RESEARCH ON THE WESTERN UGANDA BANTWANA PROGRAM ON VIOLENCE AGAINST CHILDREN IN SCHOOLS AND SURROUNDING COMMUNITIES (VACiSC) IN THE THREE DISTRICTS OF KABAROLE, KYENJOJO and BUNYANGABU
REFNo: SS3625ES

The study aims to assess the effectiveness of the Western Uganda Bantwana Program (WUBP) in preventing and responding to Violence Against Children (VAC), including child sexual abuse (CSA), in schools and surrounding communities in the three Districts of Kabarole, Kyenjojo, and Bunyangabu

Specific Objectives
1. To measure the change in knowledge, attitude and practices on risks exposures to VACiSC including CSA with focus on prevention and response among children, young adults, caregivers and teachers.
2. To assess how the WUBP aligned to the needs of communities and existing practices (structures and approaches) on prevention and response to VACiSC including CSA.
3. To evaluate the role of caregivers, teachers, para-social workers, and community leaders in creating and maintaining safe environments for children.

 Uganda 2025-02-07 18:09:14 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eva Smallegange Sophia
ID: UNCST-2023-R005788
 Effectiveness of PlayMatters in Uganda: a teacher professional development programme aiming to integrate Learning through Play as pedagogical approach in the classroom
REFNo: SS3617ES

1. To study the effectiveness of PlayMatters Teacher professional Development program on teacher practices and teacher wellbeing.
2. To study how do the effects of the intervention vary by teachers’ age, gender, displacement status, level of education and professional experience?
3. To study how do effects of the intervention vary by differences in adherence to implementation of the Teacher Continuous Professional Development (TCPD) component of the intervention?
4. To study the effectiveness of the PlayMatters Teacher professional Development program at child outcome level (cognitive, social, emotional, physical and creative skills and on their mental health and wellbeing).
5.To study the cost-effectiveness of the PlayMatters intervention.
 Netherlands 2025-02-07 18:07:38 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 Evaluation of the One Acre Fund project - making 34,000 coffee farmers more resilient by 2027
REFNo: A560ES

To establish whether all household members are equally benefiting from the impacts of the project and how? ,To determine which pursued pathways of change are the main drivers in delivering outcome and impact? ,To establish the causal effects of the project for direct project participants? ,
 Uganda 2025-02-07 18:04:15 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Michelle Brown
ID: UNCST-2022-R009670
 Describing the vocal repertoire of L’Hoest’s monkeys
REFNo: NS410ES

To test whether L’Hoest’s monkeys (Allochrocebus lhoesti) contradict the ‘social complexity hypothesis’ by determining whether they communicate in frequencies too low for human hearing.
 USA 2025-02-07 18:02:59 2028-02-07 Natural Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 Incidence and economic impacts of bovine mastitis in smallholder dairy farms in Kenya and Uganda
REFNo: A564ES

To assess knowledge of bovine mastitis, its control and treatment among smallholder dairy farmers.
To assess the effectiveness of using cell phone technology as a method of disseminating information on udder health to farmers.
To estimate the incidence rate of clinical and subclinical mastitis among recently-calved dairy cows (≤4 weeks prior to baseline data collection).
To determine the drivers of bovine mastitis among sampled dairy cows.
To estimate the monthly and annual financial losses attributed to clinical and subclinical mastitis.
 Uganda 2025-02-07 18:01:56 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Assessment of the functionality of health unit management committees in primary healthcare health facilities in Uganda: a case of health center IIIs
REFNo: HS5407ES

a) To determine the presence and functionality of HUMCs in HCIIIs
b) To determine the factors influencing the functionality status of HUMCs in HCIIIs
c) To identify any interventions needed to strengthen the performance of HUMCs in HCIIIs.

 Uganda 2025-02-07 17:59:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Factors influencing the Functionality of Medicines and Therapeutic Committees in Public Health Facilities in Uganda: A Longitudinal Assessment
REFNo: HS5391ES

a) Provide the current functionality of MTCs in public HFs
b) Determine the factors associated with the functionality of MTCs in public HFs

 Uganda 2025-02-07 17:56:57 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve Nakabembe
ID: UNCST-2024-R015226
 PReparing for OptimalPhase III/IV maTErnal Group B StreptococCal vaccine Trials in Africa
REFNo: HS5463ES

1. To generate longitudinal cohort data on pregnancies, deliveries and infant outcomes for maternal Group B Streptococcus vaccine safety assessment
2. To develop and strengthen capacities for Group B Streptococcus disease surveillance in infants less than 90 days old at Kawempe National Referral Hospital, using microbiological and molecular detection methods.
3. To explore the perceptions of pregnant women, health care providers, community members and other relevant stakeholders about the barriers and drivers for pregnant women to participate in Group B Streptococcus vaccine trials.
4. To co-create a communication/education toolkit to enhance understanding of the importance of maternal Group B Streptococcus vaccine trials and improve enrolment of pregnant women in vaccine trials in Uganda.

 Uganda 2025-02-07 17:52:29 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Okecha
ID: UNCST-2022-R011105
 CLINICOPATHOLOGICAL AND MOLECULAR PROFILE OF MALE BREAST CANCER AT THE UGANDA CANCER INSTITUTE
REFNo: HS5435ES

2. To describe the mutational profile of male breast cancer at the Uganda Cancer Institute.,1. To describe the clinico-pathological features of male breast cancer at the Uganda Cancer Institute,To describe the clinicopathological and molecular profile of male breast cancer at the Uganda Cancer Institute.,
 Uganda 2025-02-07 17:49:22 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrea Spray Lynn
ID: UNCST-2023-R007304
 Maternal mental health and early childhood development in Kawempe
REFNo: HS5448ES

PRIMARY: To assess the associations between symptoms of common MMH conditions (depression and anxiety) and child care practices and outcomes (physical growth and ECD) in the Kawempe Division of Kampala, Uganda.
SECONDARY: To assess the associations between symptoms of common MMH conditions (depression and anxiety) and underlying individual, interpersonal, and household factors.
SECONDARY: To explore what "mental health" means to mothers of children under two years of age currently living in Kawempe, how their mental health effects their daily life; the activities they do that contribute to "good" and "bad" mental health.
TERTIARY / EXPLORATORY: To determine the prevalence of common MMH conditions (depression and anxiety) in the KYC catchment area.
TERTIARY / EXPLORATORY: To create Luganda versions of the CREDI, GSED, RSES, PSS, and CFAT.
TERTIARY / EXPLORATORY: To compare the CREDI and GSED tools for measuring ECD in this context.
USA 2025-02-07 17:47:50 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MIRIAH KEMIGISHA
ID: UNCST-2022-R009927
 Evaluating Ventricle Size and Shunt Failure Rates in Ugandan Children Shunted Early in Life
REFNo: HS5382ES

General objective
To study proximal shunt obstruction and its predictors among patients with hydrocephalus secondary to myelomeningocele or encephalocele at CCHU from 2010 to 2023.

Specific Objectives.

1.To determine the rate of proximal obstruction among shunted patients with hydrocephalus secondary to myelomeningocele or encephalocele.
2.To determine the incidence of small ventricles among shunted patients with hydrocephalus following myelomeningocele or encephalocele closure.
3.To assess if ventricle size and catheter environment can predict proximal shunt failure in shunted patients with hydrocephalus secondary to myelomeningocele or encephalocele.

 Uganda 2025-02-07 17:46:28 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOYCE NAMWASE
ID: UNCST-2024-R005002
 ACCEPTABILITY, FEASIBILITY AND EFFECTIVENESS OF INVOLVING LAY HEALTH WORKERS IN RECOGNIZING AND LINKING PEOPLE WITH ALCOHOL USE DISORDER TO PRIMARY HEALTH CARE PROVIDERS
REFNo: HS5364ES

1.
To explore the perceived capability, opportunities, and motivation of LHWs to identify AUD in Ibanda district, southwestern Uganda.
2.
To implement a strategy of training lay health workers in the use of CAGE screening tool to identify AUD in Ibanda district, southwestern Uganda.
3.
To evaluate the acceptability, appropriateness, and feasibility of involving LHWs in screening for AUD in the community of Ibanda district, southwestern Uganda
 Uganda 2025-02-07 17:44:48 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 UBUMWE 2.0 Integrating Arts for Education and Psychosocial Support with Children & Youth affected by Displacement in Uganda
REFNo: SS3567ES

1. To document how the Ubumwe curriculum influenced the roles and responsibilities of the teachers;
2. To identify additional teacher professional development opportunities that teachers feel are needed to be successful in teaching the Arts;
3. To explore the ways in which the art curriculum impacted Learners’ academic and psychosocial development;
4. To assess overall feasibility, acceptability, strengths and limitations of the Ubumwe curriculum for teachers.

 Uganda 2025-02-07 17:43:07 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Factors influencing the availability and use of Electronic Medical Records Systems in Public Health Facilities in Uganda: A landscape assessment
REFNo: HS5379ES

i. Assess the extent of EMR adoption in public health facilities.
ii. Identify the types of EMR systems currently in use.
iii. Evaluate the functionality and integration of existing EMR systems.
iv. Understand the challenges and barriers to effective implementation of EMR integration.
v. Identify the factors influencing the use and adoption of EMR systems in public health facilities.
vi. Provide recommendations for enhancing EMR adoption and utilization.

 Uganda 2025-02-07 17:42:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Prossy Bibangambah Kyasimire
ID: UNCST-2024-R002215
 Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
REFNo: HS5418ES

Aim 1: Perform CCTA -based segmentation of PCAT (1a) and compare the density between PWH and PWOH (1b) in Uganda.
Aim 2: Extract PCAT radiomics features (2a) and compare differences in PCAT radiomics signatures between PWH and PWOH (2b) in Uganda.
Aim 3: Determine whether the PCAT density (from Aim 1) or radiomics signatures (from Aim 2) improve the performance of cardiovascular risk prediction in Uganda.
Uganda 2025-02-07 17:38:35 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
 Bone Health in Older Ugandan Women with and without HIV
REFNo: HS5455ES

To examine bone mineral density (BMD) and body composition in older (peri-menopausal and postmenopausal) African women who are living with HIV and taking antiretroviral therapy (ART) drugs compared to women representing similar age and background characteristics who are HIV-negative.
Uganda 2025-02-07 17:30:13 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
 Universal Protocol for Standardizing emerging Assays and Advancing vaccine Immunogenicity Assessments for Emerging and Re-emerging viral Threats through UVRI’S Partnership with the coalition for Epidemic Preparedness Innovations (CEPI)’s Centralized Clinical Laboratory Network (CLN).
REFNo: HS5330ES

To standardize and accelerate the evaluation of vaccine candidates against CEPI priority diseases, including Ebola, Marburg, Lassa, Nipah, Rift Valley Fever, SARS-CoV-2, MPOX and unidentified emerging threats, by leveraging UVRI's infrastructure and expertise.

To contribute to accelerated global vaccine development and licensure by ensuring rapid, accurate, and consistent data generation, while enhancing regional outbreak preparedness through technology transfer and capacity building.
 Uganda 2025-02-04 8:15:09 2028-02-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald  Bahati
ID: UNCST-2023-R007024
 NAVIGATING MENTAL HEALTH IN SCHOOLS PROJECT: EDUCATORS’ MENTAL HEALTH LITERACY CONCERNING ANXIETY, DEPRESSION AND NON-SUICIDAL SELF INJURY
REFNo: HS5381ES

To ascertain the educators’ confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,3. To assess educators’ level of mental health literacy about non-suicidal self-injury among school aged adolescents in selected schools in southwestern Uganda.,2. To assess educators’ level of mental health literacy about depression among school aged adolescents in selected schools in southwestern Uganda,1. To assess educators’ level of mental health literacy about anxiety among school aged adolescents in selected schools in southwestern Uganda,To assess educator’s mental health literacy about anxiety, depression and non-suicidal self-injury and their confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,
 Uganda 2025-01-31 8:00:54 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS