Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Marvious Kiwanuka
ID: UNCST-2023-R006348
Surveillance of human and vector behaviors to understand malaria transmission at sentinel sites in Uganda
REFNo: HS6483ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda in relation to human behaviors and vector bionomics.
Uganda 2025-09-30 14:43:46 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Judith Nanyondo Semanda
ID: UNCST-2025-R019750
Design and Evaluation of Human-Centred, Data-Driven Bundles for Improving Hand and Surface Hygiene Practices in Ugandan Health Facilities
REFNo: HS6507ES

1. To explore the barriers and facilitators to hand and surface hygiene compliance among clinical staff and cleaners in the health facilities of Masaka region.
2. To design data-driven hand and surface hygiene care bundles using a human centered design approach.
3. To assess the effectiveness of hand and surface hygiene care bundles in improving compliance with hand and surface hygiene practices among clinical staff and cleaners.

Uganda 2025-09-30 14:41:24 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JAMES KAWUKI STEPHEN
ID: UNCST-2025-R019616
ENERGY POVERTY, HOUSEHOLD HEALTH STATUS AND HEALTH EXPENDITURE: A STRATEGIC MANAGEMENT AND POLICY IMPLICATION IN UGANDA’S ENERGY AND HEALTH SECTORS
REFNo: SS4396ES

i. To examine the relationship between energy poverty and Household health expenditure. ii. To evaluate the relationship between energy poverty and Household health status, with specific attention the role of gender and energy usage behaviour. iii. To establish the relationship between Household health expenditure and Household health status. iv. To develop a strategic management model that incorporates affordability sensitivity and gender- responsive interventions to mitigate energy poverty and improve health outcomes.
Uganda 2025-09-30 14:40:12 2028-09-30 Social Science and Humanities Non-Clinical Trial Degree Award
Apolo Balyegisawa P
ID: UNCST-2025-R017645
Evaluation of the XF 300 Flow Cytometer, CD4 easy count kit, CD4% easy count kit and CD4/CD8 easy count kit in Tests 1112 - Explorative External Method Comparison Study and 1149.2 - Clinical Performance Study
REFNo: HS6435ES

Test 1112 - Compare the results from the XF-300 Flow Cytometer and its reagent kits with the comparator device (FACSLyric) and reagent kits Test 1149.2 - Investigate the clinical performance of the XF-300 Flow Cytometer in combination with the three kits CD4, CD4% and CD4/CD8 easy count kit.
Uganda 2025-09-30 14:39:06 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daisy Aliwaru
ID: UNCST-2025-R018043
University Management And Pedagogical Innovations In Education: A Comparative Study Of Public And Private Universities In Uganda
REFNo: SS4340ES

1. To analyse the university management structures and practices that support pedagogical innovations in education at Muni University and Uganda Christian University. 2. To examine the effect of resource allocation for pedagogical innovations in education at Muni University and Uganda Christian University. 3. To determine the effect of incentives on pedagogical innovations in education at Muni University and Uganda Christian University. 4. To examine the effect of academic freedom for pedagogical innovations in education at Muni University and Uganda Christian University.
Uganda 2025-09-30 14:36:34 2028-09-30 Social Science and Humanities Non-Clinical Trial Degree Award
Emmanuel  Arinaitwe
ID: UNCST-2021-R011754
THE SPREAD OF ARTEMISININ RESISTANCE IN AFRICA(SPARTAN 3); A longitudinal study to determine the fitness of artemisinin resistant parasites among asymptomatic infections
REFNo: HS6215ES

To detect a difference in the duration of ΔPfK13 versus wildtype infections. In addition to infection duration and parasite half-life as main outcomes of interest, we will compare ΔPfK13 and wildtype infections in terms of: - gametocyte commitment and gametocyte production - gametocyte half-life,
Uganda 2025-09-30 14:35:17 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
A Phase III/IV factorial randomised double-blind trial to compare the addition of dapagliflozin versus placebo, and rosuvastatin/ezetimibe versus pitavastatin, in patients with HIV on integrase strand transfer inhibitor-based antiretroviral therapy with elevated metabolic risk (Optimising metabolic management on integrase-based antiretroviral therapy – the OPTIMAR Study)
REFNo: HS5819ES

To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe from baseline to 48 weeks on: fasting lipids, cardiovascular disease risk assessment measures; inflammatory biomarkers; and safety and tolerability,To assess the impact of dapagliflozin vs. placebo from baseline to 48 weeks on: intermediate markers of cardiovascular disease risk; cardiovascular disease risk assessment measures; clinical consequences of increased body weight; and safety and tolerability of dapagliflozin,To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe on LDL concentration change from baseline to week 24,To assess the impact of dapagliflozin vs. placebo on absolute weight change from baseline to week 24,The overall objective of the study is to examine the impact of dapagliflozin vs. placebo on metabolic parameters in PWH with high metabolic risk who are on INSTI-based ART.,
Uganda 2025-09-30 14:11:23 2028-09-30 Medical and Health Sciences Clinical Trial Non-degree Award
Melody Niwamanya
ID: UNCST-2019-R000928
Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit Pilot in Uganda
REFNo: SS4458ES

5. Produce a refined set of tools and practical implementation guidance to inform subsequent pilots and eventual scale-up.,4. Verify that safeguarding, consent/assent, referral pathways, and data protection procedures function effectively and safely in this setting.,3. Assess data quality and preliminary measurement performance of the toolkit to identify items and scales that need refinement for clarity and consistency.,2. Establish cultural and linguistic appropriateness of items across respondent groups and identify questions that require revision based on respondent understanding and contextual fit.,1. Determine feasibility and acceptability of administering the GEEWG toolkit to learners, caregivers, teachers, school committee members, and community leaders in Kyangwali (including length, language, flow, and field logistics).,To pilot and validate a flexible, context-sensitive Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit within Kyangwali Refugee Settlement to assess its relevance, accuracy, and usability for capturing gender-transformative outcomes in MYRP-supported education interventions.,
2025-09-29 16:30:10 2028-09-29 Social Science and Humanities Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
The feasibility, acceptability and health impact assessment of the co-administration of ivermectin and albendazole vs albendazole alone, in the frame of mass drug administration to school-aged children in Uganda: A large-scale distribution
REFNo: HS6511ES

To assess the health impact of both treatment schemes and compare prevalence reduction of soil-transmitted helminth infections at school level by treatment arm ,To document safety of routine ivermectin-albendazole administration,To document the performance (i.e., coverage and reach) of the two treatment arms,To collect data on implementation-related costs and assess the additional resource needs and costs for the co-administration of ivermectin and albendazole compared to albendazole alone ,To evaluate the acceptability of sensitization and distribution strategies informed by the pilot study of co-administered ivermectin and albendazole among receiving communities,To assess the feasibility (including aspects of training, materials and processes) of the co-administration of ivermectin and albendazole compared to albendazole alone at large-scale in the frame of school-based MDA in Uganda,To assess the feasibility and acceptability of the co-administration of ivermectin and albendazole compared to albendazole alone during school-based MDA in Uganda.,
Uganda 2025-09-29 16:25:20 2028-09-29 Medical and Health Sciences Non-degree Award
MARIA NAMULWANA LOUISE
ID: UNCST-2025-R019516
Evaluating the durability of the immune response to fractional and full dose Yellow Fever vaccination (YEFE/NIFTY Extension Study )
REFNo: HS6461ES

• To describe the current age-stratified seropositivity rates in YEFE and NIFTY participants at 2-8 years after initial vaccination by vaccine dose received, and to compare seropositivity rates across trials and groups including shared data from the MRCG trial.
Uganda 2025-09-26 18:39:14 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Orodriyo
ID: UNCST-2024-R002224
PROCUREMENT MONITROING PRACTICES AND ROAD TRANSPORT SERVICE DELIVERY IN LOCAL GOVERNMENTS IN UGANDA: A CASE STUDY OF ROAD CONSTRUCTION IN ARUA CITY.
REFNo: SS4296ES

1. To assess the impact of performance score cards on road transport service delivery in Arua city.
2. To evaluate the contribution of supervision reports towards road transport service delivery in Arua city.
3. To assess the effectiveness of capacity building on road transport service delivery in Arua city.
4. To examine the moderating effect of procurement monitoring practices on road transport service delivery in Arua city.
Uganda 2025-09-26 18:35:57 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Tadeo   Nsubuga
ID: UNCST-2023-R007982
Factors associated with non-uptake and perceptions about TB preventive therapy among household contacts of TB patients in Moroto district, Uganda.
REFNo: SS4269ES

2. To understand individual and community perceptions about TPT among household contacts of bacteriologically confirmed TB patients ,1. To determine the factors associated with non-uptake of TB preventive therapy among household contacts of bacteriologically confirmed TB patients ,The overall objective is to determine the factors associated with non-uptake and perceptions about TPT among household contacts of bacteriologically confirmed TB patients in Moroto district, Karamoja sub-region, Uganda. ,
Uganda 2025-09-26 18:34:54 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eleanor Matthews
ID: UNCST-2024-R003472
Assessing development of reciprocity among juvenile chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS1024ES

This project assesses the extent to which juvenile chimpanzees use strategies of imitation and observation to learn to reciprocate cooperative behaviors common among adults i.e. grooming and coalitionary action. This project also aims to assess the extent to which cooperative tendency is observable during the juvenile life history phase, and to what extent juvenile cooperative behaviors may predict adult behavioral phenotypes.
USA 2025-09-26 18:30:33 2028-09-26 Natural Sciences Non-Clinical Trial Degree Award
ATWIINE CHRISS
ID: UNCST-2025-R018550
ASSESSMENT OF RISK FOR INDUSTRIAL SORTING MACHINE FAILURES CAUSED BY VOLTAGE FLUCTUATIONS AND STRATEGIES TO IMPROVE POWER QUALITY MANAGEMENT
REFNo: SIR551ES

iTo identify the primary causes of voltage fluctuations affecting industrial sorting machines at ACPCU Ltd in Sheema District by analyzing power supply logs and equipment response data collected over a three-month period August–October 2025. ii. To assess the impact of voltage fluctuations on the operational performance of industrial sorting machines by conducting real-time performance monitoring and error tracking from August to October 2025. iii. To evaluate the risk levels associated with voltage fluctuations using Probabilistic Risk Assessment (PRA), and to simulate potential failure outcomes using MATLAB and Monte Carlo analysis, in order to recommend mitigation strategies by November 2025.
Uganda 2025-09-26 18:29:20 2028-09-26 Engineering and Technology Non-Clinical Trial Degree Award
Stephen Gray Blair
ID: UNCST-2025-R019416
Understanding the Role of Play in Promoting Psychosocial Well-being and Learning Among Children in Refugee and Host Communities: A Contextual Study in Adjumani and Obongi Districts
REFNo: SS4275ES

Objectives of the Study This context study aims to generate evidence on how children, parents and guardians, and educators in Adjumani and Obongi districts understand, perceive, and practice play and its implications for education and psychosocial well-being. In particular, this study aims to: ● Understand the cultural and contextual meanings of play and well-being among children, parents and guardians, ECD caregivers and teachers, and community members in West Nile, ● Explore the perceptions of the role of play in supporting children’s psychosocial well-being and learning, ● Document existing practices and norms related to play and psychosocial well-being within families/at home, schools, and communities, and ●Identify barriers and enablers to using play-based learning to support children’s psychosocial well-being.
New Zealand 2025-09-26 18:28:13 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maryvian Owomugisha
ID: UNCST-2025-R017422
Financial Inclusion, Investment Acumen, Government Interventions and Financial well-being of Ugandan women
REFNo: SS4428ES

1. To examine the extent at which specific financial services have influenced the Financial Well-being of women in Western Uganda.
2. To establish whether government interventions, significantly moderate the relationship between Financial Inclusion and financial well-being of women in Western Uganda.
3. To identify a mediating effect of Investment Acumen on the relationship between financial inclusion and financial well-being of women in western Uganda

Uganda 2025-09-26 18:25:37 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Jackson Musiime Selwano
ID: UNCST-2025-R017885
Enhancing patient flow and quality of care among the edlerly within outpatient clinics of Kabale and Kitagata Hospitals in Southwestern Uganda
REFNo: HS6348ES

Research Questions 1.What are the strengths and weaknesses of the existing elderly patients’ flow management mechanisms in outpatient clinics? 2.How do elderly patients perceive their experiences within the current outpatient flow system? 3.What are the essential components of an optimized patient flow framework for elderly care? 4.How does the implementation of the new patient flow framework impact wait times, efficiency, and patient satisfaction in the pilot clinics?
Uganda 2025-09-26 18:24:27 2028-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
Impact of a Cascading Health Worker Mentorship Project on Pediatric Quality-of-Care in Busoga hospitals, Uganda – a Pre-Post Evaluation
REFNo: HS6427ES

To evaluate the perceptions from the role of mentors and mentees on the impact and sustainability of mentorship,To assess the impact of a structured mentorship program on the quality of pediatric care,To develop and evaluate a mentorship tool as a structure for quality care improvement,To assess the change in selected indicators for quality of pediatric care in six district hospitals in Uganda following the implementation of a structured and regular mentoring program ,
Uganda 2025-09-26 18:21:31 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angella Mirembe Nanteza
ID: UNCST-2022-R008741
NEURODEVELOPMENTAL OUTCOMES AND ASSOCIATED FACTORS AMONG CHILDREN BORN TO MOTHERS LIVING WITH HIV IN UGANDA.
REFNo: HS6380ES

General objective: To determine the neurodevelopmental outcomes and associated factors among children born to MLHIV in Uganda.
Specific objectives
1. To determine the neurodevelopmental outcomes of children born to MLHIV in the first 18 months of life.
2. To determine the factors associated with neurodevelopmental outcomes of children born to MLHIV in the first 18 months of life.

Uganda 2025-09-26 18:15:44 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
Effect of consumption of cape gooseberries on blood glucose control among patients with type 2 diabetes mellitus in Kampala, Uganda
REFNo: HS6017ES

To evaluate patient adherence to dietary interventions involving gooseberries,To compare change in glycated hemoglobin (HbA1c) levels among T2DM patients consuming gooseberries regularly as part of their diet with those following a regular diet. ,To assess the effect of regular consumption of gooseberries on fasting blood glucose levels in T2DM patients.,To evaluate the effect of cape gooseberries on blood glucose control among patients with T2DM in Kampala, Uganda.,
Uganda 2025-09-26 18:13:11 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Hawa Nalwoga
ID: UNCST-2021-R012081
Innovative Breast Cancer Screening to Increase Early Detection in Uganda Short title: BSESuG Research project
REFNo: HS6166ES

1. To increase knowledge about breast self-examinations (BSE) and BSE practical skills and BSE practise among women in Buhanika subcounty, Hoima district Uganda by at least 50% over a 12-month period
2. To evaluate the effectiveness of the innovative Breast Self-Examination Support Groups (BSESuG) approach in increasing the rate of detecting breast anomalies among women in Buhanika subcounty, Hoima district of Uganda by at least 30% within a 12-month period.
3. To assess the acceptability of the innovative Breast Self-Examination Support Groups (BSESuG) approach for early detection of breast cancer among women in Buhanika subcounty, Hoima district
Uganda 2025-09-26 18:11:17 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CAROLYNE OLEO
ID: UNCST-2024-R003845
DETERMINANTS OF DELAYED HEALTHCARE SEEKING AMONG PATIENTS WITH ABDOMINAL SYMPTOMS AT KYABIRWA SURGICAL CENTER, UGANDA
REFNo: HS6014ES

Main objective/ purpose:
To assess factors influencing decision to seek care in a timely manner among patients presenting with abdominal symptoms at KSC, Budondo sub county

Specific objectives:
1. To determine the median time from symptom onset to presentation among patients presenting with abdominal symptoms to KSC, Budondo sub county
2. To identify factors influencing decision to seek care in a timely manner among patients presenting with abdominal symptoms at KSC, Budondo sub county
3. To understand consequences of delayed presentation, such as increased treatment complexity or cost

Uganda 2025-09-26 18:09:15 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Okema
ID: UNCST-2025-R019099
Insulin storage in low resource settings, impact on the glycated hemoglobin.
REFNo: HS6078ES

To determine the modalities of insulin storage in children and adolescents with T1D in low resource settings and the effects on their Hemoglobin A1C (HbA1C) in northern Uganda
Uganda 2025-09-26 18:07:55 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Jef VanPuyenbroeck
ID: UNCST-2025-R017911
Monitoring anthelmintic resistance in goats in Nwoya District, Uganda
REFNo: A617ES

Main objective:
To assess the efficacy of anthelmintics commonly used by goat farmers in Nwoya district.
Specific Objectives:
1. To determine the prevalence of GIN infesting goats in Nwoya district.
2. To determine nematode species infesting goats in Nwoya district, through coproculture and molecular speciation.
3. To compare the expenses to perform routine FECRT, with McMaster and Mini-FLOTAC, for monitoring anthelmintic resistance in Uganda.
4. To assess the efficiency of survey designs and fecal egg count methods to determine drug efficacy at a certain cost and endemicity.
Belgium 2025-09-26 18:06:25 2028-09-26 Agricultural Sciences Clinical Trial Degree Award
Leah Goldmann
ID: UNCST-2024-R016618
Politicizing The Male Engagement Agenda in Feminist Movements to End Violence Against Women
REFNo: SS3930ES

This research project does not contest the strategy of engaging men in global efforts to EVAW, but rather seeks to investigate the implications of the shift in global emphasis to forwarding men as leaders, authorities, and key actors in efforts to prevent VAW in ways that could have unintended consequences for social justice movements, organizations and institutions that have been historically women-centered, women-led, and survivor-focused.

The research questions include:

Based on the gaps in the literature as described above, we propose the following

Primary Research Question:
What are the implications of the male engagement agenda on local organizations working to end violence against women in the Global South?
Secondary Research Questions:
a. Using women-led organizations working in Kampala, Uganda as a local case study, what are the impacts of the male engagement agenda on funding and programming for these organizations?
b. What is the extent of this impact? How have these organizations experienced this impact?
c. How have organizations navigated these impacts?
d. Using Men Engage Uganda as a comparative site, how and to what extent do members identify both opportunities and challenges in their relationship with feminist organizations?

USA 2025-09-26 18:05:35 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
Digital Evidence Synthesis Tool Innovation Yielding Improvements in Climate and Health
REFNo: SS4343ES

To assess the impact of the evidence products generated using digital tools on climate-health decision-making in Uganda,To assess the use of digital tools in supporting climate-health evidence to policy processes in Uganda,To identify gaps within evidence synthesis processes that necessitate the development of digital tools,To profile the evidence needs of decision makers at the climate-health nexus in Uganda,To comprehensively investigate and enhance the integration of digital tools in climate-health evidence synthesis and decision-making processes in Uganda by profiling decision makers’ evidence needs, identifying gaps in current synthesis methods, evaluating the role of digital solutions, and assessing their impact on policy outcomes.,
Uganda 2025-09-26 18:04:12 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
Applying human-centered design to develop promising Hepatitis B Birth Dose vaccine delivery models for out-of-facility and facility deliveries in Uganda
REFNo: SS4277ES

(1) To develop optimal service delivery model prototypes that enable timely administration of the HepB BD vaccine for both facility and out-of-facility births, thereby increasing vaccination coverage
Uganda 2025-09-26 17:59:03 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Denis Mpairwe
ID: UNCST-2021-R012444
Building inclusive knowledge sharing hubs (Livestock Cafés) for resilient pastoral livelihoods and rangeland restoration in East African drylands (Include2Restore)
REFNo: A621ES

The objective of Include2Restore project is to investigate how rangeland restoration can become sustainable: not only ecologically, but also socially and economically.
The project targets four main objectives:
(1) co-identify rangeland management and restoration practices that will safeguard inclusive and equitable restoration long-term on household and community levels;
(2) co-identify ways to realize new financial returns from rangeland restoration that will safeguard and promote inclusive restoration outcomes long-term;
(3) support and strengthen identified practices within local management structures by integrating them into the Livestock Cafés;
(4) co-test the potential of inclusive, rangeland restoration and sustainable management to build peace through scaling identified best practices by innovating Next Generation Livestock Cafés.
Uganda 2025-09-26 17:52:38 2028-09-26 Agricultural Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
An open-label, randomised, controlled, non-inferiority trial to compare the efficacy, safety and tolerability of a fixed dose Triple Artemisinin-based Combination Therapy (TACT) artemether-lumefantrine-amodiaquine versus first-line Artemisinin-based Combination Therapies (ACTs) for the treatment of uncomplicated Plasmodium falciparum malaria
REFNo: HS6344ES

To compare the efficacy of ALAQ vs AL and ALAQ vs ASAQ as defined by the 28-day PCR corrected adequate clinical and parasitological response (ACPR).
Uganda 2025-09-26 17:41:17 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
A Feasibility and Safety Study of the KeySuite Laparoscopic Devices for Cancer Diagnosis in Uganda
REFNo: SIR493ES

1. To evaluate potential safety issues associated with the use of the KeyScope in patients with intra-abdominal cancers or suspected cancers .
2. To determine the clinical performance of the KeyScope in viewing tissue masses in the abdomen.
3. To determine the clinical performance of the KeyLoop in retraction of the abdominal wall during laparoscopic surgery
4. To determine the acceptability of KeySuite laparoscopic devices in aiding to obtain laparoscopic biopsies

Uganda 2025-09-26 17:12:49 2028-09-26 Engineering and Technology Clinical Trial Non-degree Award
Martin Galiwango
ID: UNCST-2025-R017447
Image Classification in Dermatology: Real Time diagnosis of DCPA using edge computing
REFNo: SIR549ES

1. To identify the most optimal tier in the healthcare system where a DCPA diagnostic device would improve the diagnosis of DCPA based on health workers’ diagnostic accuracy and resource availability. 2. To train a deep learning model that can accurately diagnose DCPA. 3. To validate the deep learning model. 4. To implement the deep learning model on an edge-computing device that ensures data privacy.
Uganda 2025-09-26 16:31:26 2028-09-26 Engineering and Technology Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Focal mass drug administration for the prevention of malaria in pregnancy: a pilot randomized controlled trial.
REFNo: SS4303ES

1. Determine the feasibility and acceptability of a fMDA program with dihydroartemisinin-piperaquine (DP) as a novel component of the MiP prevention package. 2. Estimate the efficacy of fMDA to create a “safe zone” in the immediate home environment and ultimately prevent MiP. ,The scientific objective of this pilot study is to demonstrate the feasibility, acceptability, and preliminary effectiveness of a focal mass drug administration (fMDA) program for household members of pregnant women to protect against malaria in pregnancy (MiP).,
Uganda 2025-09-26 16:24:58 2028-09-26 Social Science and Humanities Non-degree Award
Abdullah Wailagala
ID: UNCST-2025-R019096
Anticipatory Action for Health Service Resilience and Detection (AHEAD) Discovery and Design Study
REFNo: HS6471ES

2) To understand the current and ideal approaches, practices, and perceptions of health workers regarding using risk data and/or information to trigger anticipatory actions.3) To collaboratively co-design, tools and frameworks for anticipatory epidemic risk monitoring and response, drawing on healthcare worker insights, existing workflows, and routine data systems at the primary health care level. 1) To assess the effectiveness and perceived impact of the cIDSR Ebola module released in response to the most recent Ebola outbreak in January 2025 in enhancing health facility readiness and response.
Uganda 2025-09-24 16:38:20 2028-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID  MUBIRU
ID: UNCST-2021-R013091
Epidemiology of Banana Bunchy Top Disease (BBTD) in Uganda: A recently discovered viral disease threatening banana production
REFNo: NS1028ES

1. To determine the genetic diversity of Banana Bunchy Top Virus variants in Uganda. 2. To screen for natural resistance of selected banana accessions against BBTV. 3. To compare the proteomic expression in the BBTV-infected banana in response to varying temperature and drought conditions.
Uganda 2025-09-24 16:36:26 2028-09-24 Natural Sciences Non-Clinical Trial Degree Award
Latim Emmanuel
ID: UNCST-2025-R019539
CONTINUOUS PROFESSIONAL DEVELOPMENT PROGRAMS, ORGANIZATIONAL LEARNING AND JOB PERFORMANCE OF REGISTERED ACCOUNTANTS IN UGANDA’S PUBLIC SECTOR
REFNo: SS4314ES

To examine the effect of workshops and seminars on the job performance of registered accountants in Uganda’s public sector.

To assess the effect of webinars on the job performance of registered accountants in Uganda’s public sector.

To evaluate the effect of mentoring and coaching on the job performance of registered accountants in Uganda’s public sector.

To evaluate the moderating effect of organizational learning on the job performance of registered accountants in Uganda’s public sector.

To advance a model necessary for improving the job performance of registered accountants in Uganda’s public sector.

Uganda 2025-09-24 16:35:28 2028-09-24 Social Science and Humanities Non-Clinical Trial Degree Award
Victoria Nzarubara Patricia
ID: UNCST-2024-R015837
Digital Transformation, Quality of Work Life, Subjective Well-Being and Coping strategies in the Uganda Police Force
REFNo: SS3574ES

7. To identify the most prevalent coping strategies adopted among police officers in the UPF.,6. To assess the perceptions of the police officers towards the digital transformation in the UPF.,5. To examine the experiences of the police officers in the UPF regarding their SWB. ,4. To determine whether coping strategies moderates the association between digital transformation and SWB among police officers in the UPF. ,3. To examine the association between digital transformation and SWB among police officers in the UPF.,2. To investigate the relationship between QWL and SWB among police officers in the UPF.,1. To assess the association between digital transformation and QWL among police officers in the UPF.,
Uganda 2025-09-24 16:30:15 2028-09-24 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Clinical Performance Evaluation of Alinity m HIV-1 Assay Using Plasma Separation Cards (PSC) versus Plasma Testing in Uganda
REFNo: HS6500ES

The primary objective of this protocol is to evaluate the performance, bias and correlation of quantitative measurement of HIV-1 RNA, of the investigational Alinity m HIV-1 assay viral load using PSC as compared with Alinity m HIV-1 assay viral load using plasma.
The secondary objective of this protocol is to evaluate the performance, bias and correlation of quantitative measurement of HIV-1 RNA, of the investigational Alinity m HIV-1 assay viral load using PSC as compared with cobas HIV-1 Quantitative nucleic acid test for use on cobas 6800/8800 systems using PSC samples.

Uganda 2025-09-23 11:10:47 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Chidiebere  Adim Victor
ID: UNCST-2025-R018777
Borderless Hustle: Kinship, Trust, and Economic Dependency in African Refugee Entrepreneurship
REFNo: SS4082ES

This study addresses a critical gap by examining how African refugee entrepreneurs mobilize kinship networks to build trust, mitigate risk, and secure the resources necessary to navigate unfamiliar and frequently hostile entrepreneurial terrains.
Nigeria 2025-09-23 11:09:24 2028-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nakayiki Lilian Nyanzi
ID: UNCST-2025-R019152
Determinants of Indigenous Fruit and Vegetable Consumption among Adults in the Rwenzori Region, Uganda
REFNo: HS6387ES

Main Objective The study aims to assess the determinants (enablers and barriers) of indigenous fruit and vegetable consumption among adults in the Rwenzori region of Uganda. Specific Objectives include; 1. To assess the availability and diversity of Indigenous Fruits and Vegetables in food markets within the Rwenzori region. 2. To determine the total intake of fruit and vegetables (and other foods consumed) by adults (18 years and above) in the Rwenzori region. 3. To develop and validate a quantitative questionnaire for assessing the determinants (barriers and enablers) of indigenous fruit and vegetable consumption among adults. 4. To assess the barriers and enablers of indigenous fruit and vegetable consumption among adults in selected communities within the Rwenzori region using the questionnaire in objective 3.
Uganda 2025-09-23 11:07:15 2028-09-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
Is Healthcare a Common Good? Philosophical Perspectives and Clinical Practices in Boston and Kampala
REFNo: SS4184ES

1. To develop a philosophical framework for conceptualizing healthcare as a
common good by drawing on African and North Atlantic philosophical traditions.
2. Explore clinicians’ conceptions of health, the common good, and professional
practice.
3. To analyze how differing conceptions of healthcare affect experiences of burnout and moral injury.
Uganda 2025-09-23 10:58:51 2028-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Honoka Yokoyama
ID: UNCST-2024-R002478
A Study of the Educational Relationship between Teachers and Students in Ugandan Secondary Schools
REFNo: SS3639ES

The purpose of this study is to clarify how the educational relationship between teachers and students is constructed in diverse relationships under the respective rationales of teachers and students, focusing on situations such as daily student guidance and learning.
Japan 2025-09-23 10:52:39 2028-09-23 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Namatovu
ID: UNCST-2025-R017197
ASSOCIATION OF INFANT AND YOUNG CHILD FEEDING PRACTICES AND NUTRITION STATUS OF CHILDREN 6-23 MONTHS IN BIDIBIDI REFUGEE SETTLEMENT –YUMBE DISTRICT-UGANDA.
REFNo: HS6243ES

General Objective
To determine the association of Infant and young child feeding practices and nutrition status of children 6-23 months in Bidibidi refugee settlement-Yumbe District Uganda.
4.2Specific Objectives

I.To determine the nutrition status (Stunting, wasting, underweight) of children aged 6-23 months in Bidibidi refugee settlement.

II.To assess the feeding practices (IYCF) (exclusive breastfeeding, continued breast feeding, introduction of solid foods, minimum dietary diversity, minimum meal frequency and minimum acceptable diet) in relation to nutrition status of children 6-23 months in Bidibidi refugee settlement.

III.To identify barriers and facilitators influencing infant and young child feeding practices of children 6-23 months in Bidibidi refugee settlement.

Uganda 2025-09-23 10:50:34 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bambeiha Asiimwe Stephen
ID: UNCST-2024-R003555
A National Survey on Health Status, Risk Behaviors and Health-Related Policies and Practices in Primary and Secondary Schools in Uganda
REFNo: HS5927ES

1. To describe the current health status in terms of physical, social, and mental well-being, among students in primary and secondary schools in Uganda 2. To describe health-related knowledge, attitudes, and practices and evaluate behavioral risk and protective factors for health among students in primary and secondary schools in Uganda 3. To assess the quality and scope of school-based health services and evaluate for disparities in these services between rural versus urban schools and private versus public schools 4. To describe challenges and good practices in school-based health services and identify opportunities for improvement
Uganda 2025-09-23 10:45:31 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAPHTAL BAGUMA
ID: UNCST-2025-R020055
CREATING AN EFFECTIVE CIVIL SOCIETY ECOSYSTEM AND BOARDROOM PROTOCOLS TO ENHANCE FINANCIAL SUSTAINABILITY OF UGANDAN NGOs
REFNo: SS4209ES

Specific Objectives 1. To investigate the relationship between civic space and the perceived financial sustainability of NGOs in Uganda 2. To investigate the relationship between funding strategies and the perceived financial sustainability of NGOs in Uganda. 3. To investigate the relationship between managing donor trust and the perceived financial sustainability of NGOs in Uganda 4. To investigate the relationship between incubation and acceleration activities and the perceived financial sustainability of NGOs in Uganda. 5. To investigate the relationship between the choice of location and events, on the one hand, and the perceived financial sustainability of NGOs in Uganda, on the other hand. 6. To investigate the relationship between talent management and the perceived financial sustainability of NGOs in Uganda. 7. To investigate the relationship between training and the perceived financial sustainability of NGOs in Uganda. 8. To investigate the relationship between access to government support and the perceived financial sustainability of NGOs in Uganda. 9. To investigate the relationship between technology usage and the perceived financial sustainability of NGOs in Uganda. 10. To investigate the relationship between the management of partnership and networks, on the one hand, and the perceived financial sustainability of NGOs in Uganda, on the other hand.
Uganda 2025-09-17 15:45:17 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
KYOMUGISHA AGATHA agathakyomugisha3@gmail.com
ID: UNCST-2025-R017288
TEACHING METHODS, PERSONALITY TRAITS MONITORING AND EVALUATION AND STUDENTS’ ACADEMIC PERFORMANCE AT NATIONAL TEACHERS COLLEGES IN UGANDA.
REFNo: SS4279ES

To examine how monitoring and evaluation practices mediate the relationship between personality traits and academic performance,To explore the mediating role of monitoring and evaluation practices in the relationship between teaching methods and academic performance,To evaluate the combined effect of monitoring and evaluation practices, personality traits, and teaching methods on academic performance in Uganda’s National Teacher Colleges.,To assess the impact of teaching methods on academic performance in Uganda’s National Teacher Colleges.,To investigate how personality traits influence academic performance in Uganda’s National Teacher Colleges.,To analyze the relationship between monitoring and evaluation practices and academic performance in Uganda’s National Teacher Colleges.,
Uganda 2025-09-17 15:43:55 2028-09-17 Social Science and Humanities Degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Harnessing DNA Methylation Variation Between Populations to Understand Disease Discordance Across Ancestries
REFNo: HS6352ES

i. Create a comprehensive mQTL resource: We aim to expand the diversity of methylation quantitative trait loci (mQTL) resources by incorporating genetic data from underrepresented populations, including Africa. The study will compare genetic architecture and selection signatures across populations and use mQTLs as instruments to identify causal relationships between DNA methylation (DNAm), genome-wide association studies (GWAS), and epigenome-wide association studies (EWAS) signals.

ii. Conduct multi-ancestry epigenetic analyses: We aim to explore disease discordance mechanisms between populations by conducting multi-ancestry EWAS with a focus on cardiometabolic and blood cell phenotypes. This will include cell-type-specific EWAS and variance EWAS analyses to understand differences across global populations.

iii. Improve disease and exposure prediction models: We will refine existing predictors of disease risk or exposure (such as smoking and alcohol use) by including data from multi-ancestry participants. This approach will help develop predictive models that are either generalizable across populations or optimized for specific ancestries.

iv. Form equitable partnerships: The study will foster global collaboration through co-developed training resources and shared analytical tools, ensuring that the research benefits a wide range of stakeholders across various regions

Uganda 2025-09-17 15:40:49 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AKANKWASA ALEX
ID: UNCST-2025-R018808
INTERNAL CONTROL SYSTEMS AND LOCAL GOVERNMENTS’ PERFORMANCE IN UGANDA; RUBANDA DISTRICT LOCAL GOVERNMENT
REFNo: SS4182ES

To examine the effect of financial controls on financial performance of Rubanda District Local Government.
(ii) To determine the influence of human resource controls on the staff satisfaction in Rubanda District Local Government.
(iii) To explore the relationship between systems control on the levels of customer satisfaction in Rubanda District Local Government.
(iv) To evaluate the moderating effect of staff retention on internal control systems and Performance of Rubanda District Local Government.

Uganda 2025-09-17 15:37:56 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
LYDIA NAKIGANDA
ID: UNCST-2025-R016917
A Qualitative Study Exploring the Role of Peer Navigators in Supporting PrEP Adherence and Retention Among Female Sex Workers in South-Western Uganda.
REFNo: HS6339ES

i. To examine the roles, characteristics, and relationship-building qualities of peer navigators in supporting FSW and integrating into health systems.
ii. To investigate the mechanisms and activities of peer navigation in community and healthcare settings that enhance retention and adherence to PrEP care among FSW.
iii. To explore the lived experiences of peer navigators as they balance community-based and professional identities in delivering healthcare services.
iv. To understand the socio-ecological factors that facilitate or hinder the success of peer navigation programs in supporting PrEP care for FSW.

Uganda 2025-09-17 15:35:04 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Obadia Mugabirwe
ID: UNCST-2024-R002359
CREATIVITY, INNOVATION, SKILLS DEVELOPMENT, AND YOUTH EMPLOYABILITY AMONG VOCATIONAL TRAINEES. A CASE OF VOCATIONAL AND SKILLS TRAINING INITIATIVES IN UGANDA (WESTERN REGION)
REFNo: SS3587ES

The main objective of this study is to assess the impact of creativity, innovation, and skills development on youth employability in Western Uganda, focusing on how vocational training programs can enhance employability outcomes by enhancing technical and soft skills, promoting career adaptability, and aligning training with labor market demands to improve job readiness and long-term career success. Specific Objectives 1. To assess the role of vocational training in enhancing the creativity of youth in Western Uganda and its contribution to employability. 2. To examine how vocational training influences the innovation capabilities of youth and their ability to adapt to evolving job market demands. 3. To evaluate the effectiveness of vocational training in equipping youth with both technical skills and essential soft skills such as communication, teamwork, and problem-solving. 4. To analyze how skills development mediates the relationship between creativity, innovation, and youth employability in Western Uganda. 5. To identify and measure key employability indicators—such as career adaptability, job search skills, career identity, and career proactivity—among vocational training graduates in Western Uganda. 6. To investigate barriers faced by vocational training graduates in transitioning to meaningful employment and propose strategies to enhance job placement and employability outcomes.
Uganda 2025-09-17 15:28:06 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
Endline evaluation of the Rights, Autonomy and Choice project (INTPA) in Kamuli & Buyende districts
REFNo: SS4170ES

1. To assess the extent to which the project\'s objectives were achieved, using the OECD DAC criteria and measuring the status of the project\'s outcome and output indicators, providing contextualized analysis of the progress achieved against the expected results, through a gender transformative and inclusive lens.
2. To foster learning from experience, capturing project challenges, lessons learnt and best practices to inform future programming in similar intervention area.
3. To assess project performance on the project indicators as indicated in the Monitoring and Evaluation Framework
Uganda 2025-09-17 14:28:07 2028-09-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daudi Hasahya-Mulongo
ID: UNCST-2025-R017131
Predictors of Retirement Readiness, and Planned Coping Strategies among Headteachers of Public Secondary Schools in Uganda
REFNo: SS4330ES

1. To assess the level of retirement readiness among headteachers of public secondary schools in Uganda.
2. To examine the predictors of retirement readiness among pre-retiring headteachers of public secondary schools in Uganda.
3. To explore the planned retirement coping strategies among pre-retiring headteachers of public secondary schools in Uganda, in managing transition into mandatory retirement.

Uganda 2025-09-17 14:00:17 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
ARTHUR KICONCO
ID: UNCST-2025-R018937
Type 2 diabetes self-management in resource limited settings: family support, self-efficacy, self-management practices, and readiness to implement Diabetes Self-Management Education and Support in informal settlements in Kampala, Uganda
REFNo: HS6253ES

i. To validate the diabetes management self-efficacy scale in Uganda Hypotheses
ii. To assess the joint association between diabetes knowledge and family support, and diabetes self-management among people with type 2 diabetes in informal settlements in Kampala Uganda
iii. To evaluate the causal effect of family support on self-efficacy among people with type 2 diabetes in informal settlements in Kampala Uganda.
iv. To explore the perceived readiness to implement DSMES for patients with type 2 diabetes in informal settlements in Kampala, Uganda using the Consolidated Framework for Implementation Research (CFIR).
Uganda 2025-09-17 13:59:03 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
ASINAI LILIAN
ID: UNCST-2024-R016497
STRATEGIC FINANCIAL MANAGEMENT PRACTICES AND SERVICE DELIVERY IN NATIONAL WATER AND SEWERAGE CORPORATION: THE CASE OF KAMPALA METRO-POLITAN REGION
REFNo: SS4102ES

Main objective: The study's general objective is to examine the effect of strategic financial management practices on service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region. Specific objectives i. To determine the significant effect of strategic planning on service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region. ii. To identify the significant effect of strategic budgeting on service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region. iii. To investigate the significant effect of strategic managing of risks and service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region. iv. To assess the significant effect of strategic ongoing procedures on service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region. v. To examine the moderating role of staff commitment on strategic financial management practices and service delivery at National Water and Sewerage Corporation, Kampala Metropolitan Region.
Uganda 2025-09-17 13:30:37 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
MARILYN BAKO ARUMADRI
ID: UNCST-2024-R002256
IMPLEMENTATION OF THE UNITED NATIONS SECURITY COUNCIL RESOLUTION 1325 AND REPRESENTATION OF WOMEN IN LEADERSHIP POSITIONS IN SECURITY INSTITUTIONS IN UGANDA
REFNo: SS4324ES

3. Identify challenges perceived and related to women involvement in decision-making leadership positions in security institutions in Uganda.,2. Examine the impact of the implementation of UNSCR 1325 on women’s representation in the security institutions in Uganda; and,1. Examine the adoption and implementation of UNSCR 1325 in the security institutions in Uganda;,The broad aim of the study is to examine the implementation of UNSCR 1325 and representation of women in decision-making leadership positions in the security institutions of Uganda.,
Uganda 2025-09-17 13:29:27 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
PACO Heart Evaluation and Risk Tracking (PACO-HEART)
REFNo: HS5985ES

Main objective: 1. Determine whether women with HIV taking DTG during pregnancy are more likely to experience hypertension, have elevated cardiovascular disease risk factors, and demonstrate vascular dysfunction postpartum.

Sub-Objectives:
1. Prospectively assess postpartum cardiovascular disease risk factors in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
2. Assess vascular function in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
3. Quantify and compare biomarkers of cardiovascular disease in peripheral plasma in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
4. Examine association between placenta pathological features (already measured in PACO cohort participants) and postpartum hypertension, vascular function, and biomarkers of cardiovascular disease


Uganda 2025-09-17 13:26:00 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Kyohairwe Baketuraki
ID: UNCST-2024-R004001
The Cost of Doing Politics: Gender Aspects of Political Violence
REFNo: SS3887ES

Aim/Overall objective: This project aims to better understand how gender shapes the scope, form, and consequences of political violence targeted at politicians, as well as to develop response strategies to reduce the problem.
RQ 1: How does gender shape the scope and form of political violence? What are the gendered dimensions of violence in political parties’ election campaigns and in the parliamentary arena?
RQ2: What are the gendered consequences of political violence on political representation in political party recruitment – and at parliamentary arenas?
RQ 3: What are the most effective and gender-sensitive responses to different forms of political violence in political party recruitment -and in the parliamentary sphere?
Uganda 2025-09-17 13:24:26 2028-09-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
NORBERT BYARUHANGA MUSISI
ID: UNCST-2024-R002079
PREVALENCE AND FACTORS ASSOCIATED WITH ADVERSE PERINATAL OUTCOMES AMONG WOMEN WITH LATE ANTENATAL CARE BOOKING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5772ES

1. To determine the prevalence of adverse perinatal outcomes among women with late ANC booking at Mbarara regional referral hospital.
2. To determine the factors associated with adverse perinatal outcomes among women with late ANC booking at Mbarara regional referral hospital

Uganda 2025-09-17 13:22:53 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Drug Optimisation for LMICs in Pregnant HIV mothers and their INfants: temporary switch to CAB/RPV long acting injections in postpartum period
REFNo: HS5982ES

To characterise drug exposure in breast milk, and drug transfer to infants through breastfeeding, as well as infant drug elimination. To characterise the elimination of CAB/RPV by describing PK profiles of IM CAB/RPV LA after last injection between 48 and 96 weeks. To establish strategies on how to safely re-establish oral ART after discontinuation of IM CAB/RPV LA at 48 weeks and switch back to daily oral ART. To explore early postpartum PK of CAB/RPV in maternal plasma and breastmilk. To demonstrate antiviral activity and impact on retention in HIV care of temporarily switching to CAB/RPV LA compared with continuation of daily oral ART over 48 weeks.,
UK 2025-09-17 13:21:16 2028-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Acceptability and feasibility of long-acting injectable antiretroviral therapy (LAI-ART) as a bridging strategy for postpartum mothers living with HIV in South Africa and Uganda
REFNo: HS5944ES

3. To assess the feasibility of adopting LAI-ART into national ART programmes and healthcare facilities, identifying programmatic considerations for optimal LAI-ART deployment.,2. To explore patient acceptability of LAI-ART during breastfeeding and as a postpartum bridging strategy to enhance adherence.,1. To develop and validate a tool for identifying and supporting women at risk of poor ART adherence postpartum.,
UK 2025-09-17 13:19:23 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
Feasibility of clinical nuance implemented using value-based community financing for the management of diabetes and hypertension in primary health care in rural South-Western Uganda
REFNo: HS6153ES

3. To assess the willingness of the community to contribute to risk pooling towards clinically nuanced VBID,2. To understand the perspectives of health workers in implementing clinically nuanced care for diabetes and hypertension in the community.,1. To explore the community’s perception of clinically nuanced VBID in the prevention and management of diabetes and hypertension.,To investigate the potential of a community-level, value-based insurance design (VBID) in enhancing clinical management and prevention of hypertension and diabetes within primary health care,
Uganda 2025-09-17 13:17:21 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Mercy Wanyana Wendy
ID: UNCST-2025-R016999
Barriers and facilitators to implementing one health approach for visceral leishmaniasis control in the Karamoja Region.
REFNo: HS6125ES

To examine barriers and facilitators to implementing one health approach for visceral leishmaniasis control in the Karamoja,2025.
Uganda 2025-09-17 13:05:50 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lillian Mugisha
ID: UNCST-2025-R018187
Impact of a Co-designed School-Based Intervention on 24-Hour Movement Behaviour and Selected Health Indicators Amongst Female Adolescents in Wakiso District, Uganda
REFNo: SS3966ES

1. Determine the level of adherence to 24-HMB guidelines among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda.
2. Explore the determinants of adherence to 24-HMB guidelines among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda.
3. Co-design a SBMB intervention with adolescent girls and teachers, targeted to enhance 24-HMB among adolescent girls aged 15-18 years in secondary schools in Wakiso District, Uganda.
4. Determine the association between accelerometer-measured 24-HMB and selected health indicators (CRF, BMI, WHtR, and BP) among adolescent girls aged 15-18 years in secondary schools in Wakiso District, Uganda.
5. Determine the impact of a co-designed SBMB intervention program on 24-HMB, and selected health indicators (CRF, BMI, WHtR and BP) among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda

Uganda 2025-09-17 13:03:31 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Mugumya  Kabaja Lawrence Kabaja
ID: UNCST-2024-R002956
Evaluating the effect of Caregiver DOTs on viral re-suppression among children in Kigezi region
REFNo: HS6505ES

1. To establish the viral re-suppression rates among children on the CAGDOTS strategy in Kigezi Region. 2. To find out the factors associated with viral load re-suppression among the CALHIV) in Kigezi region.
Uganda 2025-09-17 12:36:18 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Timothy Makumbi Kabanda
ID: UNCST-2021-R011760
MICRO RNAS PROFILING: BIOPATHOLOGIC CHARACTERIZATION AND SURVIVAL OF EARLY ONSET BREAST CANCER AMONG UGANDAN Ref No. Mak-SOMREC-2021-272
REFNo: HS3699ES

iii) To correlate aberrantly expressed miRNAs profiles with associated survival among women with EOBC.,ii) To determine the association between MicroRNAs dysregulation and the clinical pathological characteristics among women with EOBC. ,i) To determine the prevalence of dysregulated MicroRNAs expression profiles among women with EOBC.,To determine the prevalent profiles of aberrantly expressed(dysregulated) miRNAs and how they influence the specific pathological characteristics, and survival after mastectomy breast surgery for early onset breast cancer (EOBC),
Uganda 2025-09-17 12:32:26 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Integrating HIV prevention with TB household contact evaluation in Uganda (TB PrEP)
REFNo: HS6341ES

Aim 1: Assess the implementation and effectiveness of home- based HIV self-testing and PrEP initiation versus clinic referral on PrEP initiation and continuation during household TB contact investigation.

Aim 2: Examine processes of implementing HIV self-testing and PrEP initiation during household TB contact evaluation using qualitative methods.

Aim 3: Estimate the cost-effectiveness of implementing home- based HIV testing and PrEP initiation for household members of people with TB in Uganda compared to clinic referral.

Uganda 2025-09-17 12:30:43 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NUWAGIRA KENETH
ID: UNCST-2025-R016664
FINANCIAL INCLUSION AND GROWTH OF MICRO, SMALL AND MEDIUM-SIZED ENTERPRISES (MSMES) IN KAMPALA CITY, UGANDA.
REFNo: SS3991ES

Main Objectives
The purpose of the study is to investigate the effect of financial inclusion on growth of micro, small and medium-sized enterprises (MSMEs) in Kampala City, Uganda.

1.4 Specific objectives
i) To determine the effect of credit accessibility on the growth of MSMEs in Kampala City, Uganda.
ii) To establish the effect of mobile money services on the growth of MSMEs in Kampala City, Uganda.
iii) To explore the effect of financial literacy on the growth of MSMEs in Kampala City, Uganda.

Uganda 2025-09-17 12:28:56 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Twinamasiko Specioza
ID: UNCST-2022-R008954
Empowering Ugandan Refugee–Host Communities in Becoming Climate Resilient: The Case Studies of Nakivale and Rhino Camp Refugee Settlements
REFNo: NS983ES

1. To assess the resilience of refugees and their host communities to water access and land tenure in Nakivale and Rhino Camp
2. To monitor water quality within the refugee settlements and host communities of Nakivale and Rhino Camp.
3. To analyze hazards and farming practices within the refugee settlements and host-communities of Nakivale and Rhino Camp refugee-host communities
4. To document the different traditional practices and indigenous knowledge on agriculture, water source preservation and forest conservation prevalent among the refugee and host communities of Nakivale and Rhino Camp Refugee settlements.
5. To identify ways in which traditional environmental practices and indigenous knowledge can complement the contemporary modern scientific policies of environmental conservation and protection in refugee-host communities

Uganda 2025-09-17 12:27:48 2028-09-17 Natural Sciences Non-Clinical Trial Degree Award
Sadia Mohamed Mahad
ID: UNCST-2024-R004826
Prevalence and Factors Associated with Substance Use Among Refugees In Nakivale Settlement South-Western Uganda
REFNo: HS6217ES

i. To determine the prevalence of substance, use among refugees in Nakivale Refugee Settlement. ii. To identify and describe the modifiable and non-modifiable factors associated with substance use among refugees in Nakivale Refugee Settlement.,
Somalia 2025-09-17 12:08:46 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jazira Tumusiime
ID: UNCST-2024-R003664
EXPLORING CAREGIVERS AND HEALTH WORKERS’ PERCEPTIONS TOWARDS HPV VACCINATION AT MBARARA REGIONAL REFERRAL HOSPITAL ADOLESCENT CLININC AND BWIZIBWERA HEALTH CENTRE IV, UGANDA
REFNo: HS6193ES

To identify the barriers and facilitators influencing the uptake of HPV vaccination among adolescents at Mbarara Regional Referral Hospital and Bwizibwera Health Centre IV in southwestern Uganda.,To assess caregivers\' and healthcare workers\' knowledge and perceptions about HPV vaccination at Mbarara Regional Referral Hospital and Bwizibwera Health Centre IV in southwestern Uganda.,To explore caregivers’ and healthcare workers’ perceptions of HPV vaccination and identify the barriers and facilitators affecting the uptake of the HPV vaccine among adolescents at Mbarara Regional Referral Hospital and Bwizibwera Health Centre IV in southwestern Uganda.,
Uganda 2025-09-17 11:22:16 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Miria Nandera
ID: UNCST-2021-R012140
SCHOOL CLIMATE AND WORK ENGAGEMENT MEDIATED AND MODERATED BY WORK-LIFE BALANCE AND JOB EMBEDDEDNESS OF PRE-PRIMARY TEACHERS IN CENTRAL UGANDA
REFNo: SS4033ES

1. To examine the influence of school climate on teacher work engagement of pre-primary teachers in Central Uganda.
2. To assess the influence of school climate on work-life balance of pre-primary teachers in Central Uganda.
3. To analyse the influence of work-life balance on teacher work engagement of pre-primary teachers in Central Uganda.
4. To test the mediating role of work-life balance on the influence of school climate on teacher work engagement of pre-primary teachers in Central Uganda.
5. To find out the moderating effect of job embeddedness on the influence school climate on teacher work engagement of pre-primary teachers in Central Uganda.
Uganda 2025-09-17 11:19:34 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Ibrahim Adabara
ID: UNCST-2025-R019039
AGENTIC AI FOR CYBERSECURITY: A FRAMEWORK FOR THE DESIGN AND GOVERNANCE OF RESILIENT AUTONOMOUS DEFENSE SYSTEMS
REFNo: SIR547ES

1.3 Main Objective

The primary objective of this research is to construct a theoretically grounded and ethically aligned framework for conceptualizing, simulating, evaluating, and governing AAI systems in cybersecurity. The framework will serve as a strategic model for autonomous defensive agents, focusing on secure, transparent, and accountable operation in adversarial environments, in alignment with legal and normative expectations.

1.4 Specific Objectives

i. To develop a reference model for agentic AI systems integrating autonomy, ethical responsiveness, and adaptive reasoning by synthesizing existing literature and formalizing the framework within the first phase of the study.

ii. To design and implement a simulation-based methodology that models adversarial threat scenarios and tests agentic AI responses within a defined experimental period, using performance and ethical indicators as measurable outputs.

iii. To construct a multi-criteria evaluation framework that defines and measures agentic system performance in terms of transparency, latency, proportionality, and normative alignment, validated through simulated test cases in the second phase.

iv. To propose and validate a governance and ethical oversight model for agentic AI deployment, incorporating regulatory review, stakeholder auditability, and normative safeguards by the final phase of the project, following empirical evaluation.
Nigeria 2025-09-17 11:18:20 2028-09-17 Engineering and Technology Non-Clinical Trial Degree Award
Ronald Bisegerwa
ID: UNCST-2022-R011022
Accuracy of Pulse Oximeters with Profound Hypoxia
REFNo: HS6506ES

To generate two to three evidence-based recommendations to regulatory and procurement bodies within six months of study completion to guide pulse oximeter selection for diverse populations.,To collect and contribute data on pulse oximeter accuracy across diverse skin tones to an open-access device performance database by the study’s end, enabling manufacturers to refine pulse oximeter technology and ensure equitable performance across all skin tones, especially in low-resource settings.,To replicate the UCSF Hypoxia Lab in Uganda by establishing a fully equipped and operational facility within a year to evaluate pulse oximeter accuracy across diverse skin tones and hypoxia levels.,To evaluate the accuracy of pulse oximeters under controlled hypoxic conditions in a diverse population in Uganda, with a focus on understanding and addressing disparities in device performance related to skin pigmentation.,
Uganda 2025-09-12 17:03:12 2028-09-12 Medical and Health Sciences Clinical Trial Non-degree Award
Pauline Amuge Mary
ID: UNCST-2023-R005532
LC-REVITALIZE – A Long Covid Repurposed Drug Study
REFNo: HS6370ES

-To assess the efficacy of repurposed drugs compared to their
respective placebos in reducing standardized symptom severity scores
in participants with Long Covid.
-To compare the symptom burden (e.g., anxiety, depression, overall
well-being) in participants with Long Covid treated with repurposed
drugs versus their respective placebos.
- To assess whether symptom burden worsens in participants with Long
Covid treated with study drugs versus placebo, specifically when
symptoms are reported across multiple scales.
- To assess changes in exercise capacity over time of participants with
Long Covid treated with study drugs versus their respective placebos.
- To measure specific Long Covid pathophysiological biomarkers of study
drugs versus their respective placebos.

Uganda 2025-09-12 17:00:13 2028-09-12 Medical and Health Sciences Clinical Trial Non-degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
Caregiver-Adolescent Sexuality Communication among Refugee and Host Communities in Southwestern and Northern Uganda (CONNECT)
REFNo: SS4216ES

3. Policy and community engagement objective: To establish and evaluate the contribution of multi-sectorial and development partners’ working committee in translation, sustainability, and scalability of the impacts of the caregiver-adolescent SRH communication intervention with resultant improvement in adolescent SRH policy and programming within refugee and host communities’ context in Southwestern and Northern Uganda. ,2. Gender Transformative Objective: To assess the social, economic, and cultural factors that influence the effective implementation of a gender-equitable caregiver-adolescent SRH communication and family functioning intervention within a multinational and multicultural refugee and host community context in Southwestern and Northern Uganda. ,1. Research objective: To contextualize, design, implement, and evaluate the effectiveness of caregiver-adolescent SRH communication intervention in refugee and host communities’ settings in Southwestern and Northern Uganda. ,The general objective of the project is to implement and evaluate a parent/caregiver-adolescent communication intervention on sexual and reproductive health (SRH), targeting social and cultural gender norms that hinder parental involvement in sexuality education among refugees and host communities in Nakivale and Bidi Bidi Refugee Settlements, Uganda. The project will assess the intervention\'s effectiveness in addressing the challenges faced by displaced and dysfunctional families in refugee and host community settings.,
Uganda 2025-09-12 16:55:54 2028-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Barnabas Atwiine
ID: UNCST-2022-R010629
Status of Haemophilia Care and Management in Uganda: A Situation Analysis
REFNo: HS6293ES

3. To explore health workers’ knowledge and attitudes towards haemophilia care and management in Uganda. ,2. To assess the availability of equipment, supplies, and medicines used in the diagnosis and management of Haemophilia patients in Uganda.,1. To assess the proportion of health facilities that care for people with haemophilia in Uganda.,To assess the status of haemophilia care and management among health facilities in Uganda.,
Uganda 2025-09-12 16:54:23 2028-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnifred Namazzi Birabwa
ID: UNCST-2025-R017998
AN ASSESSMENT FOR THE APPROPRIATE CULTURALLY RESPONSIVE PEDAGOGY IN IMPLEMENTING THE COMPETENCY BASED CURRICULUM AMONG INDIGENOUS BATWA COMMUNITIES IN UGANDA
REFNo: SS4097ES

1. What Batwa culturally responsive learning experiences can teachers integrate in teaching to effectively implement the CBC in Batwa heterogeneous classrooms? 2. How can the teachers utilize Batwa learners’ cultural backgrounds to address their learning needs when implementing the CBC in Batwa heterogeneous classrooms? 3. How can teachers integrate culturally responsive teaching methods to enable effective implementation of the CBC in Batwa heterogeneous classrooms? 4. What are the challenges of integrating CRP into the implementation of the competency based curriculum in Batwa heterogeneous classrooms?
Uganda 2025-09-12 16:53:22 2028-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Grace Ahimbisibwe Miriam
ID: UNCST-2021-R012129
Assessing the Effects of Immune Suppression of Pregnancy on the HIV Latent Reservoir in African Women with HIV Participating in P1078 (IMPAACT NWCS 663).
REFNo: HS6371ES

1.Evaluate changes in inflammation and immune activation markers in black African WWH from the antepartum through 48 weeks postpartum periods.
a. Describe participant level changes in inflammation and immune activation markers from the antepartum through 48 weeks postpartum periods.
2.Evaluate changes in the HIV latent Reservoir (LR) size in black African WWH from the antepartum through 48 weeks postpartum periods.
a. Describe participant level changes in HIV LR size from the antepartum through 48 weeks postpartum periods.
3.Identify immune correlates of the HIV LR from the antepartum through 48 weeks postpartum periods in black African WWH.

Uganda 2025-09-12 16:50:35 2028-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS WENANI MWISAKA
ID: UNCST-2025-R018729
ENHANCING TVET- INDUSTRY COLLABORATION FOR MARKETABLE SKILLS DEVELOPMENT IN EASTERN UGANDA.
REFNo: SIR542ES

1. To identify industry-specific skill gaps and requirements to guide collaborative training initiatives.
2. To assess the effectiveness of existing partnerships between TVET institutions and industries in fostering market-relevant skills.
3. To explore barriers to effective collaboration between TVET institutions and industries

4. To design a strategic framework for strengthening partnerships and aligning training programs with industry needs.


Uganda 2025-09-12 16:42:50 2028-09-12 Engineering and Technology Non-Clinical Trial Degree Award
Doreen Kirungi
ID: UNCST-2025-R019078
AN EXPLORATION OF THE POTENTIAL OF DIGITAL NOMADS AS A VIABLE MARKET SEGMENT FOR UGANDA: A CASE STUDY OF SOUTHWESTERN UGANDA
REFNo: SS4069ES

1. To profile digital nomads in South Western Uganda. 2. To assess the availability, quality, and accessibility of services and facilities offered in Southwestern Uganda. 3. To design a framework for creating awareness about digital nomads as a viable market segment in southwestern Uganda.
Uganda 2025-09-12 16:41:54 2028-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Mariam Nanteza Ssesanga
ID: UNCST-2025-R020432
Research Funding for Ugandan Institutions (2015-2025): A decadal analysis and an exploration of institutional sustainability and individual experiences amid recent global funding Cuts.
REFNo: SS4186ES

i. To analyze research funding patterns and trends for Ugandan institutions from 2015 to 2025, examining changes in funding sources, volumes, and allocations.
ii. To explore the perspectives and lived experiences of individual researchers in Uganda regarding the impact of recent funding cuts by the US and other global north funders.
iii. To investigate the actions, strategies, and adaptability measures adopted by Ugandan research institutions to sustain operations and research activities in response to recent global funding reductions.

Uganda 2025-09-12 16:40:30 2028-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Julius Lwanga
ID: UNCST-2022-R010322
THE RELATIONSHIP BETWEEN NUTRITIONAL STATUS AND DIETARY PATTERNS AMONG PATIENTS WITH CHRONIC KIDNEY DISEASE AND ASSOCIATED COMORBIDITIES ATTENDING OUT-PATIENT CLINICS IN KAMPALA
REFNo: HS2888ES

IV. Assess the relationship of dietary patterns and nutritional status with CKD and associated comorbidities management,III. Evaluate the comorbidities in patients with CKD attending out-patient clinics in Kampala.,II. Assess the dietary patterns of patients with CKD attending out-patient clinics in Kampala.,I. Determine the nutrition status of patients with CKD attending out-patient clinics in Kampala.,The general objective of the study is to determine the relationship of nutritional status and dietary patterns among patients with Chronic Kidney Disease and associated comorbidities management attending out-patient clinics of Mulago Renal Clinic, Kiruddu Renal Clinic and Panorama Medical Center Kampala.,
Uganda 2025-09-12 16:39:09 2028-09-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Constance Nakato Nakimuli
ID: UNCST-2024-R003618
Predicting the quality of biomass briquettes using a machine learning approach
REFNo: SIR459ES

i. To develop a comprehensive dataset that accurately characterizes biomass briquettes, briquetting processes, and feedstock properties, providing a strong foundation for machine learning model development
ii. To develop robust machine learning models capable of accurately predicting the key quality parameters of biomass briquettes, enabling informed decision-making for process optimization
iii. To empirically validate the practical feasibility of biomass briquettes for diverse cook stoves, focusing on the relationship between briquette characteristics and cook stove efficiency through data visualization techniques

Uganda 2025-09-12 16:37:50 2028-09-12 Engineering and Technology Non-Clinical Trial Degree Award
Ronald Opito
ID: UNCST-2022-R011357
PROFILING THE DISEASE BURDEN IN TESO THROUGH COMMUNITY BASED MEDICAL EDUCATION AND RESEARCH SERVICES AT SOROTI UNIVERSITY, A PROSPECTIVE STUDY. (PRODIB_COBMERS).
REFNo: HS6508ES

1. Assess the prevalence of common non-communicable disease (NCDs) in Teso subregion and the capacity of the health workers to diagnose them.
2. To determine the trends of common infectious diseases over a period of 10 years. (TB, Malaria, UTIs, hepatitis B, STIs, RTIs etc) within the Teso sub-region and assess the effectiveness in the preventive measures over the same period.
3. To establish the prevalence of common NTDs (Schistosomiasis, Onchocerciasis, trypanosomiasis etc) around wetland communities in eastern Uganda and the effectiveness of control measures.
Uganda 2025-09-12 16:20:07 2028-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Seju Kang
ID: UNCST-2024-R015536
Developing Environmental Wastewater-Based Surveillance in Non-Sewered Areas in Low-Income Contexts
REFNo: HS5809ES

Research questions: To develop and validate a community-based environmental surveillance approach to detect infectious disease pathogens in urban areas with non-sewered sanitation. Objective 1: To design and implement a sampling plan that identifies high-risk locations for pathogens in non-sewered urban environments. Objective 2: To analyze pathogen levels and correlate findings with demographic and spatial data.
South Korea 2025-09-12 16:17:44 2028-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
alice namatovu
ID: UNCST-2025-R017415
EVALUATION OF THE EFFECTIVENESS OF BACTERIOPHAGE COCKTAILS AGAINST MULTI-DRUG-RESISTANT BACTERIA ON PATIENTS WITH DIABETIC FOOT ULCERS ATTENDING SELECTED REFERRAL HOSPITALS IN UGANDA
REFNo: HS5652ES

Main objective:
To assess the efficacy of bacteriophages in the management of diabetic foot wounds/ulcers in animal models and among patients attending the selected referral hospitals in Uganda.

Specific Objectives
i) To determine the biological and genotypic characteristics of lytic bacteriophages against the MDR- bacteria isolated from diabetic wounds of patients.

ii) To determine the virulence genes of the bacteria isolated from DFU patients and those genes associated with antimicrobial resistance.
iii) Determine the phage receptor genes on the MDR bacteria isolated from DFU patients.

iv). To evaluate the effectiveness of the identified Bacteriophage preparation/cocktail in the healing of induced diabetic wounds in mice.
v). To evaluate the effectiveness of the identified bacteriophage preparation/cocktail in the healing of diabetic foot wounds on patients in selected referral hospitals in Uganda.

Uganda 2025-09-12 16:14:57 2028-09-12 Medical and Health Sciences Clinical Trial Non-degree Award
Solomon Mbina Adomi
ID: UNCST-2024-R015658
EFFECTS OF LYOPHILIZED LEAF EXTRACT OF KHAT (Catha edulis Forsk) ON HEPATORENAL SYSTEM AND LIPID METABOLISM IN HIGH FAT DIET INDUCED HYPERLIPIDEMIC MALE ALBINO WISTAR RATS
REFNo: HS5753ES

1. To characterize the bioactive compounds in lyophilized Catha edulis leaf extract using Gas chromatography-mass spectrometry (GC-MS) technique. 2. To determine the molecular interactions between bioactive compounds of Catha edulis leaf extract. and key proteins involved in lipid metabolism (leptin, adiponectin, and HMG-CoA reductase) using molecular docking analysis. 3. To determine the effect of lyophilized Catha edulis leaf extract on serum liver function parameters, (Alanine aminotransferase (ALT), Aspartate aminotransferase (AST) and Alkaline Phosphatase (ALP), bilirubin, Albumin). in HFD-induced hyperlipidemic male albino Wistar rats. 4. To evaluate the effect of lyophilized Catha edulis leaf extract on kidney function indices (Urea, creatinine, serum electrolytes) in HFD-induced hyperlipidemic male albino Wistar rats. 5. To determine the effect of lyophilized Catha edulis leaf extract on serum leptin and adiponectin hormones levels in HFD-induced hyperlipidemic male albino Wistar rats. 6. To evaluate the effect of lyophilized Catha edulis leaf extract on serum lipid profile (Total cholesterol, High-density lipoprotein, low-density lipoproteins, and triglycerides) in HFD induced hyperlipidemic male albino Wistar rats. 7. To examine the effect of lyophilized Catha edulis leaf extract on the histology of the liver and kidney of HFD induced-hyperlipidemic male albino Wistar rats.
Nigeria 2025-09-12 16:13:25 2028-09-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Magololo Mutesi Fiona
ID: UNCST-2024-R015533
Changes in inpatient antibiotic use and antimicrobial resistance rates, through a collaborative quality improvement intervention: a study on adult surgical wards at Mulago National Referral Hospital.
REFNo: HS6321ES

4.1 Objectives. 4.1.1 General objective To reduce irrational inpatient antibiotic use by at least 10% in the adult surgical wards of Mulago National Referral Hospital using a collaborative quality improvement intervention approach. 4.1.2 Specific Objectives. 4.1.2.1 Specific Primary objectives. 1. To determine baseline and closeout rates of irrational inpatient antibiotic use in the adult surgical wards of Mulago National Referral Hospital at Month one and Month seven respectively. 2. To describe antimicrobial resistance rates and drug susceptibility patterns of commonly isolated bacterial pathogens obtained from patients admitted to the adult surgical wards of Mulago National Referral Hospital during the 24 months preceding this study (July 2023-June 2025). 3. To determine monthly rates of irrational antibiotic use on the adult surgical wards of Mulago National Referral Hospital from Month two to Month six, during the QI intervention implementation. 4. To explore health worker perceptions and lived experiences on antimicrobial resistance, antibiotic prescription and antimicrobial stewardship as well as the impact of AMR on the adult surgical wards of Mulago National Referral Hospital, at Month one and Month seven. 5. To reduce irrational antibiotic use by 10%, through developing and implementing a collaborative quality improvement intervention to on antimicrobial stewardship on the adult surgical wards of Mulago National Referral Hospital. 5.1.2.2 Specific Secondary objectives. 6. To describe the change in monthly rates of irrational inpatient antibiotic use following a quality improvement intervention in the adult surgical wards of Mulago National Referral Hospital. 7. To describe the relationship between irrational inpatient antibiotic use rates and antimicrobial resistance rates in adult gastrointestinal surgical wards of Mulago National Referral Hospital. 8. To describe the change in antimicrobial resistance rates and drug susceptibility profiles of isolates obtained from patients admitted to the adult surgical wards of Mulago National Referral Hospital during this study, compared to those of patients admitted in 24 months before this study (24 months preceding month 1).
Uganda 2025-09-12 12:24:29 2028-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jerry Okal Okoth
ID: UNCST-2025-R016719
Evaluation of the Challenge Initiative (TCI)
REFNo: SS3773ES

The objective of the deep dive is to assess whether and to what extent TCI inputs and activities have led to or contributed to intended IOs in Uganda, and the process for how those IOs were achieved. ,
Kenya 2025-09-10 12:20:33 2028-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Othman Kakaire
ID: UNCST-2019-R000359
Monitoring, Learning and Evaluation for the Commercial Introduction and Scale-up of DMPA-SC in East Africa (DMPA SC MLE STUDY)
REFNo: HS6422ES

General objective: To support the monitoring, learning and evaluation of the commercial introduction of DMPA-SC in the private sector in Uganda, including identifying scalable strategies for increasing uptake of DMPA-SC. Specific objectives: To determine the value proposition of commercially available DMPA-SC To explore the effective strategies to increase awareness, acceptability, and uptake of DMPA-SC and SI at pharmacies and drug shops To understand how DMPA-SC and related services are being managed and delivered by pharmacy and drug shop providers/outlets (staffing and training, counselling, supportive supervision, etc.) To understand the strategies and approaches that are effective in driving quality of service delivery and counselling
Uganda 2025-09-09 8:31:27 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
WEB-BASED INTERVENTION FOR ALCOHOL AND SUBSTANCE ABUSE AMONG YOUNG UNIVERSITY STUDENTS
REFNo: SS1785ES

To assess feasibility and effectiveness of the web-based intervention for prevention and treatment of ASUD problems among youth 18-24 years attending Universities in Uganda,To develop a web-based intervention for prevention and treatment of ASUD problems among youth 18-24years attending Universities in Uganda,To establish the prevalence of ASUD problems among youth 18-24years in selected Universities,To contribute to the improvement of the quality of ASUD treatment services in Uganda among the youth through the development of a web-based intervention and assess its feasibility and effectiveness for the prevention and treatment of ASUD among University students in Uganda,
Uganda 2025-09-09 8:17:25 2028-09-09 Social Science and Humanities Clinical Trial Non-degree Award
SHARON NAMIIRO MIRIAM
ID: UNCST-2023-R006661
Prevalence of Human Papilloma Virus in lung cancer tumors of adult people with and without HIV, and its association with lung cancer stage at diagnosis.
REFNo: HS6375ES

1. To determine the prevalence of Human Papilloma Virus (HPV) in primary lung cancer tumors of adult patients living with and without HIV 2. To compare the most prevalent HPV subtypes in the primary lung cancer samples of adult people living with and without HIV in Uganda. 3. To determine the association of HPV with lung cancer stage among adults with and without HIV.
Uganda 2025-09-09 16:45:06 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Blasio BWAMBALE Bisereko
ID: UNCST-2020-R014574
Influence of Terrestrial and Wetland Ecosystems on Species occurrences of Aedes and Culex Mosquitoes as vectors of Arboviruses in Northern Uganda
REFNo: NS1003ES

(i) To determine the occurrence and abundance of the species of Aedes and Culex mosquitoes in selected terrestrial ecosystems of districts in West Nile and the Acholi Sub-region in Northern Uganda
(ii) To determine the composition and abundance of the species of Aedes and Culex mosquitoes in selected wetland ecosystems of districts in West Nile and the Acholi Sub-region in Northern Uganda
(iii) To determine the prevalence of occurrence of arboviruses in the species of Aedes and Culex mosquitoes from the mentioned selected ecosystems of districts of West Nile and the Acholi Sub-region in Northern Uganda

Uganda 2025-09-09 16:43:05 2028-09-09 Natural Sciences Non-Clinical Trial Degree Award
Adoke Yeka
ID: UNCST-2021-R004300
Randomised controlled trial to assess the efficacy of artemisinin combination therapies in a setting of emerging artemisinin resistance in Uganda.
REFNo: HS6327ES

To assess the 42-day clinical and parasitological efficacy of artemether-lumefantrine (AL) and pyronaridine-artesunate (PA) for the treatment of uncomplicated P. falciparum malaria in Uganda.
Uganda 2025-09-09 16:41:47 2028-09-09 Medical and Health Sciences Clinical Trial Non-degree Award
Mike Mugude
ID: UNCST-2022-R010442
FEASIBILITY AND ACCEPTABILITY OF USING THE LONG-ACTING CABOTEGRAVIR-RILPIVIRINE INJECTIONS AMONG HIV-INFECTED ADOLESCENTS ATTENDING BOARDING SCHOOLS IN KAMPALA CITY, UGANDA
REFNo: SS4300ES

Primary objective: To understand how the implementation of long-acting
injectable antiretroviral therapy programs can be carried out among
ALHIV who attending boarding school education in Kampala city”.
Secondary objectives:
I. To determine the willingness to use the LA-ART among ALHIV
in boarding schools in Kampala.
II. To determine the acceptability of the LA-ART among ALHIV in
boarding schools in Kampala.
III. To explore the lived experiences of ALHIV regarding the uptake of
oral ART and factors that may influence the use of the LA-ART
boarding schools.
Uganda 2025-09-09 14:18:00 2028-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deogratius Okengo
ID: UNCST-2025-R017738
Youth Participation in Akiriket Activities: Pathways to Sustainable Peace in Kotido Municipality Karamoja Uganda.
REFNo: SS4252ES

i. To investigate the roles of youth within Akiriket assemblies in Kotido, Karamoja Uganda
ii. To examine the contributions of youth to sustainable peace by their participation in Akiriket
iii. To identify the challenges for youth to sustain their engagement in Akiriket peace activities

Uganda 2025-09-09 14:06:52 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
EVALUATION OF COMMUNITY-BASED INTEGRATED SCREENING AND DIAGNOSIS OF TUBERCULOSIS, ASTHMA AND COPD, AND ITS IMPACT ON ANTIBIOTIC PRESCRIPTIONS IN SELECTED COMMUNITIES IN UGANDA
REFNo: HS6308ES

Sub – study one Primary objective 1. To evaluate the barriers and facilitators of integration of community-based TB, asthma and COPD screening and diagnosis in selected rural and urban communities of Masaka and Wakiso districts. Secondary objective 2. To describe the implementation outcomes of integrating community-based TB, asthma and COPD screening and diagnosis in selected communities of Masaka and Wakiso districts using the RE-AIM framework. Sub – study two Primary Objective 1. To determine the effect of referral of patients, through community screening initiatives, on antibiotics prescriptions patterns and practices in primary health care facilities. Secondary objectives 2. To identify factors influencing provider decisions to prescribe antibiotics to people who screen negative for TB at selected primary health facilities in Masaka, Wakiso and Rakai districts in Uganda. 3. To evaluate patients’ understanding of antibiotics prescription following a negative TB screen in selected communities in Masaka, Wakiso and Rakai districts in Uganda.
Uganda 2025-09-09 14:03:21 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Akulume
ID: UNCST-2023-R005452
THE USE OF MICRO-ENTREPRENEURSHIP TO STRENGTHEN THE COMMUNITY HEALTH WORKER PROGRAM IN RURAL UGANDA
REFNo: HS6368ES

To describe the access to health care services and products within the study districts To determine the factors that affect how CHEs execute their duties To map geographical information on access to healthcare providers and products in selected clusters. To determine how CHWs execute their work and the factors that affect them. To explore stakeholder�s perception regarding the contribution of community health entrepreneurship to the community health work program To estimate the frequency of use of CHE-services in general and for children <5 suffering from acute fever or diarrhoea To describe the role of CHEs in the care-trajectories for children suffering from acute fever or diarrhoea
Uganda 2025-09-09 14:02:05 2028-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Martha Naluwende
ID: UNCST-2025-R019681
End Term Evaluation of the Make Way Programme in Uganda
REFNo: SS4114ES

The study aims to evaluate the relevance, effectiveness, coherence, and sustainability of the Make Way programme in Uganda. It will assess how well the programme addressed the SRHR needs of marginalized youth, the impact of its advocacy and capacity-building efforts, and the strength of its partnerships—especially the implementation of the “Leading from the South” approach. Additionally, the study will document lessons learned and good practices to inform future SRHR programming and policy.
Uganda 2025-09-09 13:59:55 2028-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
MARY MUGABEKAZI
ID: UNCST-2024-R002638
Prevalence and Risk Factors Associated with Recent and Long-Term HIV Infections Among Newly Identified HIV Positive Clients in Kyenjojo District, Western-Uganda
REFNo: HS6381ES

To find out the prevalence and risk factors associated with recent & long-term HIV infections among newly identified HIV positive clients in Kyenjojo District, Western-Uganda.,
Uganda 2025-09-09 13:48:40 2028-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Atuhaire Rosemary
ID: UNCST-2024-R003132
Parenting Styles, Students’ Connectedness and Academic Adjustment among Pre- Service Teachers in Universities of South Western Uganda
REFNo: SS3370ES

7. To evaluate the mediating role of student connectedness in the associations between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,6. To investigate the relationship between student connectedness and academic adjustment among pre-service teachers in universities in south western Uganda.,5. To explore the correlation between parenting styles and student connectedness among pre-service teachers in universities in south western Uganda.,4. To examine the relationship between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,3. To assess the levels of academic adjustment among pre-service teachers in universities in south western Uganda.,2. To identify prevalent parenting styles among pre-service teachers in universities in south western Uganda.,1. To investigate how academic adjustment varies across demographic variables among pre-service teachers in universities in south western Uganda.,To investigate the associations between parenting styles, students\' connectedness, and academic adjustment among pre-service teachers in the universities of south western Uganda.,
Uganda 2025-09-09 13:44:49 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
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