Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sebastian Linnemayr
ID: UNCST-2021-R012696
 INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
REFNo: HS1286ES

We propose to test INMIND in a pilot, 3-arm randomized controlled trial (RCT) in Uganda with two intervention groups. All participants (including in the control group) will receive information about the importance of behavioral routines, as is part of the standard adherence counseling for treatment initiators, and create personalized ART adherence anchoring strategies. In the first intervention group, participants will additionally receive text messages to keep adherence and their anchoring strategy salient. In the second group, we add small incentives awarded conditionally on taking ART pills within a time window that corresponds to participants’ personalized anchoring strategy to increase the immediate rewards of adherence.

The Specific Aims
1.Develop the intervention using the ADAPT-ITT framework and evaluate the feasibility and acceptability of INMIND.
2: Test the preliminary effectiveness of the intervention, including the relative effectiveness of two different implementation approaches
3. Collect data in preparation for a subsequent R01 application
 USA 2021-03-15 2024-03-15 Medical and Health Sciences Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
 The effect of psycho-education on clinical outcomes among patients with a first episode psychosis in central Uganda - A pilot randomized control trial
REFNo: HS1026ES

The study objectives are to (a) Conduct formative work and develop a manual for delivering psycho-education messages by Village Health Team (VHTs) members to individuals with first episode psychosis (FEP) and their families in central Uganda. (b) Examine the efficacy of psycho-education on symptom severity, stigma and retention in care. (c) Document feasibility and acceptability of implementing this intervention as well as barriers to its implementation
Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
JOSEPH Ngonzi
ID:
Quality Improvement Initiative in the Department of Obstetrics and Gynaecology
REFNo: HS967ES

1) To measure current health outcomes in the unit
2) To describe and analyze current process, behaviors, resources and availability
3) To develop and implement changes in current practices to improve outcomes while maximizing resources.
4) To monitor and evaluate health outcomes in the department of OB/GYN

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
Margaret Joanita Mutumba Nakalembe
ID:
Multi-level Analysis on Implementation of Low-Cost IVF in Sub-Saharan Africa: A Case Study of Uganda.
REFNo: HS1214ES

The objective of this study is to explore how LCIVF has been implemented in the public health system of Uganda. The more specific questions include; 1) How has LCIVF been operationalized at the micro-level within the clinical practice? 2) How has the public hospital at the meso-level organized itself to facilitate the implementation and provision of LCIVF? 3) How have macro-level factors influenced the implementation of LCIVF within the public health system? 4) How effective has the implementation of LCIVF been in addressing accessibility and affordability of infertility services in Uganda?
 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 MUTATIONAL PROFILE OF TRIPLE NEGATIVE BREAST CANCER IN WOMEN SEEKING CARE AT THE UGANDA CANCER INSTITUTE
REFNo: HS1264ES

1. To describe the mutational profile of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
2. To describe the relationship between the mutational load and the primary tumor size of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
3. To describe the differences in mutational profile by histological type in patients with triple negative breast cancer in women seeking care at the Uganda Cancer Institute

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 An Evaluation of the Pediatric Care Process in Uganda for Improvement of Quality of Care
REFNo: HS1227ES

The primary objective of this study is to evaluate the typical pediatric care process at a representative sample of hospitals in Uganda
 Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Severe MAlaria A Research and Trials consortium: A protocol for a prospective case control observational study
REFNo: HS1231ES

To characterise the contemporary epidemiology (including features at presentation and the diagnostic and treatment pathway) of severe malaria presenting to hospital for admission in children in Africa, through conducting a prospective multicentre observational study across 7 sites in 6 countries, enrolling two cohorts of hospitalised children (i.e. stratified) with severe and non-severe malaria. For this study, severe malaria will be defined as children with a positive POC pHRPT2 test (Paracheck) meeting WHO criteria or Teule criteri. For severe malaria, we will characterise the proportions presenting with different severe complications, or combination of any of or all of these, and compare these proportions across sites. Secondary Objectives i. To compare baseline characteristics of admitted children with severe and non-severe malaria. ii. To document time from presentation to the hospital ‘gateway’ (e.g. outpatients or emergency/triage centre) to ward admission and time to first dose of parenteral artesunate to assess whether delays in initiating definitive antimalarial treatment could contribute to malaria severity. iii. To estimate the incidence of significant post-discharge events to day-180 including readmission (all-cause and for malaria (i.e. relapse)) and all-cause mortality in severe and non-severe malaria. iv. To develop (year 1) and evaluate (years 2 and 3) a point-of-care quantitative plasma Plasmodium falciparum histidine-rich protein2 (pfHRP2) test for estimating total body parasite burden, which could be used to swiftly identify those at greatest risk of poor outcomes.
Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
Tom Lutalo
ID:
Measuring adult health and mortality in Low- and Middle-Income Countries
REFNo: HS640ES

1. To evaluate the accuracy of survey data on adolescent and adult mortality collected retrospectively through siblings’ survival histories (SSH), compared to the reference mortality data collected prospectively.
2. To test whether the siblings of respondents can be reached and interviewed via mobile phone, in order to collect data on the risk factor of adult mortality

 Uganda 2021-03-10 2024-03-10 Medical and Health Sciences Non-degree Award
Levicatus Mugenyi
ID: UNCST-2020-R014759
 Understanding Factors Associated with IPT Completion among Recipients of Care on ART/IPT Aligned Multi-month Refills across the Differentiated Service Delivery Models
REFNo: HS1228ES

The primary objective is to understand factors associated with completion of IPT among clients in MoH’s integrated IPT/ART models.
Specific objectives:
1.To compare IPT completion rates amongst clients across the five DSD models: Facility-Based Individual Management (FBIM), Facility-Based Group (FBG), Fast Track Drug Refill (FTDR), Community Client Led ART Delivery (CDDP), and Community Drug Distribution Points (CCLAD).
2.To understand individual and facility level factors associated with IPT completion across the different DSD models
3.To compare IPT uptake across the different DSD models
4.To compare the frequency of adverse events (AEs) reported by clients on IPT across the different DSD models
5.To document patient and service provider KAP towards the IPT/ART integrated model

 Uganda 2021-03-10 2024-03-10 Medical and Health Sciences Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A Phase 1 Trial of ChAdOx1- and MVA-vectored Conserved Mosaic HIV-1 Vaccines in Healthy, Adult HIV-1-negative Volunteers in Eastern and Southern Africa
REFNo: HS844ES

Safety
ï‚· To evaluate the safety and tolerability of a prime boost vaccine regimen utilizing non-replicating simian adenovirus (ChAdOx1) followed by non-replicating poxvirus modified vaccinia virus Ankara (MVA) in adults in Eastern and Southern Africa
Immunogenicity
ï‚· To evaluate the specific T-cell immune responses induced by the ChAdOx1.tHIVconsv1 followed by MVA.tHIVconsv3&4 vaccines in vaccine recipients.
SECONDARY
ï‚· To assess tHIVconsvX-specific T-cell responses of for their frequency, breadth and duration in vaccine recipients.
ï‚· To assess functional T-cell responses in vaccine recipients that inhibit replication in vitro of viruses of major HIV-1 clades A, B, C and D.
EXPLORATORY
ï‚· To assess induction of plurifunctional tHIVconsvX-specific memory T cells in the vaccine recipients.
ï‚· Characterization of the gut microbiome composition and richness.
 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 USING SHORT MESSAGE SERVICE REMINDERS AND MOBILE MONEY INCENTIVES TO ENHANCE LINKAGE TO CARE OF PRESUMPTIVE TUBERCULOSIS PATIENTS IN UGANDA: A RANDOMISED CONTROLLED TRIAL
REFNo: HS993ES

To evaluate the TB diagnostic process and linkage to care by doing cohort analysis.

2. Develop and adapt an SMS reminders and MM incentives to improve linkage to care among TB patients.

3. Conduct a randomized controlled trial of SMS reminders and MM incentives sent to presumptive and confirmed TB patients to improve linkage to care and treatment.

4. To build sustainable capacity in TB research clinical trials in Uganda.

Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jude Onyango Tadeo
ID:
FAMILY SUPPORT, DIABETES SELF-MANAGEMENT, AND GLYCEMIC CONTROL AMONG PATIENTS ATTENDING DIABETIC CLINICS OF REGIONAL REFERRAL HOSPITALS IN EASTERN UGANDA (FS-DSM-GC STUDY)
REFNo: HS1040ES

Research Study objectives:
General objective:
To examine the association between perceived family support, diabetes self-management behavior and glycemic control among patients attending Regional Referral hospitals in the eastern region of Uganda.
Specific objectives:
1. To determine the association between perceived family support and diabetes self-management behavior among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.
2. To determine association between perceived family support and glycemic control among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.

 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jonathan Mayito
ID:
Utility of the monocyte to lymphocyte ratio in diagnosing latent tuberculosis among HIV-infected individuals with a negative tuberculosis symptom screen.
REFNo: HS1066ES

1. To determine the diagnostic performance of the monocyte to lymphocyte ratio against IGRA in diagnosing latent TB among HIV-infected individuals with a negative tuberculosis symptom screen.
2. To determine the change in the monocytes to lymphocytes ratio measured at baseline, and three months among HIV-infected individuals during tuberculosis preventive therapy.

 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
Evaluation of the Safety and Tolerability of the ‘LeVe CPAP Flow Generator’ in Healthy Volunteers at Mengo Hospital in Kampala Uganda
REFNo: HS1250ES

To determine the safety, tolerability and acceptability of the LeVe CPAP Flow Generator’ among healthy volunteers at Mengo Hospital and to ensure they do not cause harm.
 Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Patrice Mawa Akusa
ID:
Establishing a pool of school-going adolescent girls and boys as immunisation ambassadors in Entebbe, Uganda
REFNo: HS1215ES

Overall rationale One way of engaging and empowering mothers and communities and linking them to immunisation services is by use of their own daughters and sons. The relationship between mother and her daughter is full of learning experiences and one of the strongest bonds. Mothers also have emotional relationship with their sons and will likely listen to them. Objectives The objective of the project is to establish a pool of school-going adolescent girls and boys as‘immunisation ambassadors’ and change agents able to engage and empower mothers and community members and link them to maternal and neonatal immunisation services by training them on vaccines and leadership skills.
Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
 UNDERSTANDING STAKEHOLDER PERSPECTIVES, PREFERENCES AND EXPERIENCES FOR THE RETURN OF PHARMACOGENOMICS RESEARCH RESULTS AMONG PEOPLE LIVING WITH HIV AIDS.
REFNo: SS735ES

GENERAL OBJECTIVE

To explore stakeholder perspectives, preferences and experiences in contribution to development of locally contextualized institutional guidelines for returning individual pharmacogenomics research results to people living with HIV.

SPECIFIC OBJECTIVES

1. To explore stakeholders’ attitudes, perspectives and experiences towards the return of individual pharmacogenomics research results among people living with HIV.

2. To determine factors that influence decisional preferences for receiving individual pharmacogenomics research results among people living with HIV

3. To develop institutional guidelines for the return of individual pharmacogenomics research results to research participants.

 Uganda 2021-03-03 2024-03-03 Social Science and Humanities Degree Award
Patrice Mawa Akusa
ID:
Exploring immune responses in primary and more advanced Schistosoma mansoni infection and treatment of preschool-age children using Aurora spectral flow cytometry
REFNo: HS1223ES

Objective 1: To characterize immune responses of PSAC in primary and more advanced S. mansoni infection

Objective 2: To determine the effect of PZQ treatment of S. mansoni on immune responses in PSAC.

 Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
LYDIA NAKIGANDA JACENTA
ID:
Demographic characteristics, attitudes, behaviours and sexually transmitted infections among female sex workers using HIV Pre- Exposure Prophylaxis living in the fishing communities around Lake Victoria Basin, Uganda.
REFNo: HS813ES

i.To define demographic characteristics
ii.To explore sexual behaviours, in association with PrEP prescription,
iii. To explore self-reported adherence rates and correlates of adherence
iv. To examine the STI disease burden, use of condoms and explore associations between condom use and STIs.
v. To explore factors that might facilitate or challenge PrEP use, such as side effects and stigma, and
vi. To understand FSWs’ experiences, perceptions of & attitudes towards PrEP

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Jaffer Okiring
ID:
Increasing malaria trends amidst routine core interventions among residents of varying transmission settings of Uganda
REFNo: HS1033ES

1) To compare the malaria trends measured using Test Positivity Rate and Total laboratory confirmed cases of malaria relative to incidence in high malaria settings in Uganda
2) To determine household level factors associated with malaria incidence at 68 sites with varying malaria transmission intensity.
3) To investigate the environmental factors associated with malaria incidence and how these factors modify the impact of core vector control interventions in Uganda
4) To develop a model that can predict malaria incidence in different epidemiological settings and how the incidence will vary with the roll out of different core interventions in Uganda.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Evaluation and Scale-up Strategy for the Doctor@Distance Programme in Uganda
REFNo: HS955ES

4.3 General objective
To evaluate the Doctor@Distance programme by identifying current benefits and gaps and exploring the path for further development of the programme and potential embedment of the programme in the larger health system.

4.4 Specific objectives
1.To explore what the multi-stakeholder perceptions are on the design and daily practice of the Doctor@Distance programme
2.To analyse the design and current utilisation of the Doctor@Distance programme and identify potential gaps in its coverage (how often is it used, by whom, for which diseases, etc.)
3.To evaluate the current healthcare gaps in the communities in which the community health entrepreneurs of the Doctor@Distance programme are active
4.To explore how the Doctor@Distance programme can be scaled-up to other districts within Uganda
5.To investigate multi-stakeholder perceptions on the possibility of integration of the Doctor@Distance programme in the larger health system in Uganda


 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
 Pre-hospital exposure to, and antimicrobial drug resistance patterns among febrile children presenting to St. Mary’s Hospital Lacor, northern Uganda
REFNo: HS1091ES

General objective To determine the prevalence of pre-hospital exposures to antibiotics, common bacteria and their susceptibility to microbial drugs among febrile children presenting to a tertiary health facility in northern Uganda. Specific objectives 1. To determine the prevalence of pre-hospital exposures to antibiotics among febrile children presenting at St Mary’s Hospital Lacor 2. To establish the common bacterial isolates among febrile children presenting at St Mary’s Hospital Lacor 3. To determine the microbial resistance patterns among febrile children presenting at St Mary’s Hospital Lacor
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Aidah Nanvuma
ID: UNCST-2024-R015734
 EVALUATING THE CAPACITY BUILDING MODEL USED TO NURTURE INDEPENDENT RESEARCH INVESTIGATORS AT THE INFECTIOUS DISEASES INSTITUTE, UGANDA
REFNo: HS1100ES

Objective 1: To describe Capacity Building Unit support activities and scholarly outputs and outcomes since inception. Objective 2: To determine how particular components of the unit scientific and non-scientific support(Inputs) contribute to scholar (past and present) outputs and outcomes since inception. Objective 3: To identify and address areas of improvement in unit support activities through the engagement of current and former stakeholders (beneficiaries and benefactors).
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 A Study to Validate and Improve an Automated Image Analysis Algorithm to Detect Tuberculosis in Sputum Smear Slides: Version 1.0 dated Nov 2020
REFNo: HS1144ES

1. Validate the platform, and assess efficiency improvements from computerized detection approaches.
a. Perform a slide specimen digitization (400 slides, 98 images/slide, 39,200 images).
b. Classify all images as dark/medium/light based on color histogram data.
c. Assess accuracy vs. manual microscopy, and sensitivity/specificity vs. bacterial culture.
d. Develop a new image analysis algorithm by integrating software applications that include Artificial Intelligence (AI) approaches via Convolutional Neural Networks (CNN).
2. Quantify slide staining quality and variability through the use of novel methods which exploit the color spectra of stained slides.
a. Determine factors which led to poor slide preparation.
b. Test a new quality control method (HistoQC) to standardize clinical slide preparations

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
THOMSON LAKWO LURONI
ID: UNCST-2023-R007843
 Evaluation of the Diagnostic Tests in Areas Hypoendemic for Onchocerciasis –Uganda: a follow-up study.
REFNo: HS1220ES

Objective 1: Evaluate the distribution of anti-OV-16 antibody and other markers of O. volvulus infection in multiple age groups over time in an area of active intervention for onchocerciasis
Objective 2: To determine whether a serologic threshold of 2% that modeling suggested is consistent with interruption of transmission.
Objective 3: Monitor for sero-reversion of OV-16 antibody positivity in a nested cohort of individuals who participated in the previous study.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Predicting the Future: Incipient Tuberculosis (PreFIT)
REFNo: HS1242ES

1.1 Aim:
To validate the clinical performance, cost, and feasibility of a package of ready-to-use new and existing candidate diagnostic assays for the prediction of the development of active TB.
1.2 Objectives:
1. Establish a multi-country diagnostic evaluation cohort of highly exposed TB contacts free of co-prevalent active TB, followed prospectively for active TB development over a 12-months period, and collect and store biological specimens from these contacts at pre-set time-points for laboratory testing; and
2. Validate a package of candidate assays for their predictive accuracy (sensitivity, specificity, positive and negative predictive values) for incident TB, feasibility, and cost. Based on combining results for the different tests, cost-optimised predictive algorithms will be derived.

 Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Miriam Nansunga
ID:
ASSESSMENT OF THE SAFETY AND EFFICACY OF COMMON MEDICINAL PLANTS OF CENTRAL UGANDA ON IMPAIRED LEARNING AND MEMORY IN RATS
REFNo: HS648ES

1. To identify medicinal plants of Central Uganda used in the management of memory impairment.
2. To determine the effect of the aqueous extracts of the 5 most commonly mentioned plants on escape latency in the Morris Water Maze and step down latency in Passive Avoidance test.
3. To determine the effect of the total crude extracts of the two most effective plants on: acetylcholine, glutamate; muscarinic receptor M1, M3 and M5; glutamate receptors AMPA and NMDA in the hippocampus and orbital frontal cortex

4. To establish the safety and toxicity profile of the two most active plants extracts on memory and learning enhancement.

 Uganda 2021-02-26 2024-02-26 Medical and Health Sciences Degree Award
Leevan Tibaijuka
ID: UNCST-2021-R012986
 Predictors for preterm neonatal mortality at Mbarara Regional Referral Hospital
REFNo: HS469ES

General objective
To Describe the Predictors for Preterm Neonatal Mortality among preterm babies delivered at Mbarara Regional Referral Hospital (MRRH).
Specific objectives
1. To describe the neonatal mortality of preterm babies at Mbarara Regional Referral Hospital
2. To describe the association of antenatal care attendance, antenatal corticosteroid use and mode of delivery with preterm neonatal death at Mbarara Regional Referral Hospital

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Francis Ekadu
ID:
Uganda Bribery Index
REFNo: SS392ES

To increase citizens awareness on the prevalence, gravity and impact of corruption in uganda
 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Lucrèce Ahovègbé Yémalin Judith
ID:
Evaluation of two medicinal plants on key factors causing treatment failure in Hepatitis C infection
REFNo: HS1004ES

1. Evaluate the antiviral and anti-mutagenic effect of A. nilotica and T. ciliata on HCV in presence and absence of DAA
2. Evaluate the effect of A. nilotica and T. ciliata on induced mutation in HCV infection in presence and absence of DAA
3. Determine effect of A. nilotica and T. ciliata on immunologic parameters involved in body response to HCV in presence and absence of DAA
4. Investigate the genotypes of HCV circulating in African region (Uganda, Benin) and their response in vitro to DAAs

 Benin 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
PAUL KATO KALYEBARA KALYEBARA
ID:
INCIDENCES OF RE-MARRIAGE, LIVE CHILDBIRTH AND RECURRENCE OF INCONTINENCE AMONG WOMEN THAT UNDERWENT OBSTETRIC FISTULA REPAIR AT MBARARA REGIONAL REFERRAL HOSPITAL FROM 2010 TO 2019
REFNo: HS1060ES

General objective
To determine the incidences of re-marriage, live childbirth and recurrence of incontinence among women who had successful obstetric fistula repair at Mbarara Regional Referral Hospital from 2009 to 2019.
Specific objectives
1. To determine the incidence of re-marriage among women who had successful fistula repair at Mbarara Regional Referral Hospital from 2010 to 2019.
2. To determine the incidence of live childbirth among women who had successful obstetric fistula repair at Mbarara Regional Referral Hospital from 2010 to 2019.
3. To compare recurrence rates of incontinence after childbirth occurring among women who had successful genitourinary and rectovaginal fistula repair at MRRH from 2010 to 2019.

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
 Political Economy Analysis of sub-national health management in Eastern and Southern Africa
REFNo: SS664ES

This study will explore the dynamics taking place at sub-national level (e.g. within counties or districts) as well as between national and sub-national levels along the following objectives:
1. Analyze the environment for decision-making and implementation of health plans at sub-national level, including existing formal and informal processes for decision-making; political, financial, social, and other influences on sub-national prioritization, decision-making and resource allocation, including relevant changes over time (e.g. post-devolution), and how data and evidence play a role.
2. Identify and characterize key stakeholders with a role in sub-national health management and systems—key characteristics will include technical capacity, their use of data and evidence, the relationships and power dynamics between them, and the existing structures for engagements with non-health sector authorities, both formal and informal.
3. Assess existing formal and informal accountability mechanisms for sub-national decision-making for health (both within the health system and for external stakeholders like beneficiary communities, sub-national decision-makers (county/district), and development partners) with a view to identify ways to improve the relative effectiveness of accountability mechanisms in decision processes.
4. Analyze social sector spending trends and beneficiaries, their relation to health sector policies, and how local governance structures influence them, where available.
5. Develop draft plan for piloting strategies to address challenges identified by the PEA, including proposed implementation and monitoring and evaluation approaches, as appropriate.
6. Analyze the policy environment on community health, including key stakeholders, to identify potential approaches for integrating a new community health extension worker program into existing systems, especially at district level
7. Analyze the current digital health innovations governance and accountability structures, (including key stakeholders across sectors and how their responsibilities and priorities overlap,) to identify strategies for strengthening existing structures, enhancing accountability and minimizing duplication

Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Silvia Kahihu Wairimu
ID:
Improving the Impact of VSLAs on Refugees’ and Host Communities’ Self- reliance, Resilience and Economic Capacity
REFNo: SS658ES

Our main objective is to investigate different facets of the VSLA (structure, benefits, and barriers as well as future opportunities) with the aim of optimizing its design. This is because we hypothesize that optimizing the structure of the VSLA will lead to increased financial inclusion of the group members as well as social capital.
 Kenya 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Dianah Ahumuza Ateenyi
ID:
The impact of tax incentives on the realisation of economic and social rights: A focus on tax holidays and the right to basic education in Uganda
REFNo: SS666ES

1. To examine the historical background and justification of tax incentives generally and tax holidays specifically especially in Uganda.
2. To explore the adequacy of the legal and policy framework on tax incentives, especially tax holidays in Uganda and how it impacts revenue for the realisation of ESRs, specifically the right to basic education;
3. To analyse the relationship between government revenue and basic education financing and how it the realisation of the right to basic education.
4. To recommend appropriate legal, policy and administrative reforms for the better management of tax incentives generally and tax holidays specifically for the realisation of Uganda’s international and domestic ESRs obligations, with specific emphasis on the right to basic education.

 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory Viruses (INSIGHT Protocol No. 003 version 3.0, dated 27 August 2013); Flu003 PLUS AND Genomic Study: INSIGHT Protocol No. 004 version 2.0, dated 27 August 2013 -A substudy of qualifying INSIGHT studies
REFNo: HS1108ES

The objectives of this study for participants with confirmed influenza are to:

1. Characterize individuals who are hospitalized with influenza in terms of demographics, co-morbid conditions, prior influenza vaccination (seasonal, including 2009 H1N1) and pneumococcal vaccination, and use of antivirals, overall and according to influenza type, A or B, and influenza A subtype.

2. Estimate the percent who die and who develop a composite outcome, overall and according to the identified influenza type or subtype: death, a requirement for mechanical ventilation or admission to the intensive care unit (ICU), or prolonged hospitalization following enrollment (duration of hospitalization >28 days) at 60 days after enrollment.

3. Study risk factors, (e.g., patient and viral characteristics, geographic location, influenza type and subtype) for mortality and the composite outcome of death, a requirement for mechanical ventilation or admission to the ICU, or prolonged hospitalization following enrollment (duration of hospitalization >28 days).

4. Establish a repository of oropharyngeal, nasal and lower airway samples to determine a laboratory diagnosis; to molecularly characterize the virus, including subtype, antigenic and genetic analyses; to identify known signature mutations for antiviral drug resistance, mutational evolution, and additional re-assortment; and assess possible co-pathogens.

5. In a subset of patients requiring mechanical ventilation, to collect paired upper and lower airway samples to molecularly characterize the virus according to anatomic location, assess the potential emergence of antiviral resistance and assess possible co-pathogens.

6. Establish a repository of serum and plasma for future studies, including measurement of biomarkers that predict disease severity and measures of host response to infection with influenza virus.

7. Compare the characteristics and outcomes of patients infected with different influenza virus types and subtypes, including 2009 H1N1 virus, over time and by geographic region.

8. Identify and characterize other viral and bacterial pathogens, including coinfections.

The objectives of this study for participants with targeted non-influenza viral respiratory infections are to:

1. At enrollment, characterize individuals who are hospitalized with a targeted viral respiratory disease in terms of possible source of infection and mode of transmission, demographics and co-morbid conditions.

2. At 28 and 60 days of follow-up, estimate the percent who die, require admission to the ICU, have prolonged hospitalization, or recover.

3. Establish a repository of prospectively collected serum, plasma and respiratory tract specimens for future studies, including measurement of biomarkers that predict disease severity and measures of host immune response to infection.

 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Non-degree Award
Jane Frances Namatovu
ID: UNCST-2020-R014353
 CONTINUING PROFESSIONAL DEVELOPMENT FOR PRIMARY CARE DOCTORS IN LOW RESOURCE SETTINGS: DEVELOPING A COMPETENCY-BASED FRAMEWORK
REFNo: HS1170ES

1.To determine the CPD training needs of primary care doctors working in public general hospitals (GHs) and health center IVs (HC IVs) of central Uganda
2.To explore the perceived barriers to and facilitators of CPD among primary care doctors working in public GHs and HC IVs of central Uganda
3.To explore the views of key stakeholders on CPD for doctors working in public GHs and HC IVs of central Uganda
4.To develop a competency-based CPD framework for primary care doctors working in public GHs and HC IVs of central Uganda
 Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Targeting Domestic Animals and Tsetse Fly Vectors to Control Nagana and Accelerate Elimination of Acute Sleeping Sickness from Hot Spot Villages of Eastern Uganda
REFNo: A107ES

The main objective of this study will be to determine whether targeting hotspot villages would accelerate elimination of rHAT The specific objectives of this project will be to determine; i. If rHAT hotspot village-based interventions [two doses of diminazene aceturate 40 days apart at the beginning of the intervention and monthly RAP] will progressively reduce T. brucei s.l. reservoir in cattle and hence insidious rHAT transmission. ii. The drivers of insidious rHAT transmission in hotspot rHAT hotspot villages in Dokolo and Kaberamaido districts.
Uganda 2021-02-25 2024-02-25 Agricultural Sciences Non-degree Award
NOLBERT GUMISIRIZA KAGAMBIRWE
ID:
Investigating how the specialized and decentralized treatment healthcare models for all forms of epilepsy in Uganda fared in the covid-19 pandemic
REFNo: HS1156ES

1. To assess the government strategy of decentralized care and treatment for persons with all forms of epilepsy in Uganda, before COVID-19.

2. To assess the effects of the COVID-19 pandemic on access to epilepsy care in Uganda

3. To assess the socio-economic and mental health effects of the COVID-19 pandemic on persons with epilepsy in Uganda.

4. To generate ideas and strategies to improve the existing models for epilepsy care in Uganda∙

Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
 Impact of Covid-19 on maize and dairy value chains in Uganda
REFNo: SS699ES

Specific objective: To assess the impact of Covid-19 on the maize and dairy value chain in Uganda. Specific objective: to determine how the COVID-19 pandemic affected production, marketing/sales and welfare of actors/households along the two value chains.
 Belgium 2021-02-25 2024-02-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 Effectiveness of Inclusive Home-based Early Learning Model in Increasing Access to Early Child Education (ECE) for Children in Marginalised Communities
REFNo: SS740ES

1. To describe contextually relevant pedagogical practices that result into better child school readiness outcomes in home based ECCE centres
2. To compare the impact of the play- based ECCE curriculum model program on children’s school readiness relative to the control group
3. To determine the impact of pedagogical mentorship program on teacher professional well-being, classroom quality, and children’s school readiness relative to a control group

 Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 SITUATION ANALYSIS OF THE IMPACT OF COVID - 19 ON GLOBAL FUND TO END MODERN SLAVERY’S SUPPORTED PROGRAMMES TO END COMMERCIAL SEX EXPLOITATION OF CHILDREN AND ENDING LABOUR EXPLOITATION
REFNo: SS757ES

This is a program evaluation study focusing on CSEC and OLR programs. As a result, the primary questions are divided into two corresponding to the two study sub-components.

Broadly, this study seeks to establish the likely impact of COVID 19 on the implementation of the Commercial and Sex Exploitation programmes supported by the Global Fund to End Modern Slavery, in Kampala and Karamoja areas.
Uganda 2021-02-25 2024-02-25 Social Science and Humanities Non-degree Award
Samwel Wangombe
ID:
INTERNAL CONTROLS, REGULATORY MECHANISMS AND FINANCIAL ACCOUNTABILITY IN INDIGENOUS NON-PROFIT ORGANISATIONS IN UGANDA
REFNo: SS734ES

1. Describe the accounting internal controls applicable to indigenous non-profit organisations.
2. Determine the significance of accounting internal controls on the level of compliance with legal and/or regulatory requirements.
3. Determine the significance of accounting internal controls on the choice of self-regulatory mechanism.
4. Evaluate the extent to which resource dependence theory determines the quality and consistency of financial reporting.
5. Explain the relationship between internal controls, regulatory mechanisms and financial accountability.
Kenya 2021-02-24 2024-02-24 Social Science and Humanities Degree Award
Murungi Elizabeth Mwebesa
ID:
Creating an Ecosystem exemplifying Cross Sector Cooperation Approach towards road safety of motorcycles in Kampala, Uganda
REFNo: SIR43ES

Each safe riding behavior belongs to either Priority (P), Speed (S) or Comprehension (C). So it is imperative to understand which factors affect which behavior and the extent of this effect.Therefore the objectives of this study are;
a)To identify the PPM (Push, Pull, Mooring) factors that promote each of the safe riding behaviors (PSC component).

b)To understand the extent to which push, pull and mooring factors influence the behavior of riders that have had contact with these parameters and those that haven’t.

c)To create a Theory of Change (ToC) model to propose the possible road map to changing the behaviors of riders. Leveraging on these two results above, a proposal of the possible road map to changing the behavior of riders will be made by creating a Theory of Change (ToC) table

 Uganda 2021-02-24 2024-02-24 Engineering and Technology Degree Award
Goretty Nagawa Mary
ID:
Implications of Land Use and Land Cover Changes towards Household Food Security in the Forested and Grassland areas of Mount Elgon Slopes
REFNo: NS122ES

Overall aim of the study
The study seeks to analyze land use and cover changes; and to establish the contribution of this towards carbon emission levels, and climate variations; and to assess the implication towards household food security by looking at the quality, diversity and quantity acquisition procedures within the households of Mount Elgon slopes.
1.3.2 Specific objectives
1. To analyse land use and cover changes on Mt Elgon slopes and assess their impact on CO2 effluxes from the soil in forest and grass land cover/use types.
2. To assess climate variability in relation to land use and land cover changes; and CO2 effluxes in the forested and grassland areas of Mt Elgon Slopes.

3. To assess the impact of land use and cover changes on household food security on Mount Elgon slopes.

 Uganda 2021-02-24 2024-02-24 Natural Sciences Degree Award
Emanuele Colonnelli
ID:
Do Corruption Perceptions Kill Competition?
REFNo: SS654ES

Increasing competition in public procurement is a key priority in many developing countries. High and widespread participation in the public procurement market is crucial to ensure the proper functioning of the procurement system, and ultimately high quality public investment. Public procurement of goods and services represents the primary area of government investment, accounting for 14.5% of GDP in low-income countries.
In this study, which takes place in Uganda, we aim to study the role played by a key potential barrier to competition in the public procurement market: firms' perception of public procurement as a rigged system, driven by bureaucratic corruption and personal connections. If these perceptions are widespread among market participants, governments may find it challenging to increase competition for public procurement. Furthermore, if perceptions spillover across public bodies, perceptions of systemic corruption may negatively affect competition even in those public bodies which manage to achieve high performance standards. This may in turn hinder bureaucrats' incentive to increase the performance of their organization, since efforts to reform a public body may not directly map into better perceptions of it among the public.
 Italy 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A Phase 3b, Randomized, Multicentre, Open-Label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-Acting Cabotegravir Plus Long-Acting Rilpivirine From Current Antiretroviral Regimen in HIV-1 Infected, Virological Suppressed Adults in Sub-Saharan Africa. (Cabotegravir And Rilpivirine: Efficacy and Safety Study: The CARES Study)
REFNo: HS1117ES

1.To demonstrate the non-inferior antiviral
activity of switching to IM RPV LA+CAB
LA administered every 2 months compared
with continuation of cART administered
daily over 12 months in HIV-1 infected
participants in a resource limited setting.
2.To demonstrate the antiviral and
immunologic activity of switching to IM
RPV LA+CAB LA every 2 months
compared to continuation of cART over 12
and 24 months of follow-up
3.To evaluate the safety and tolerability of
switching to RPV LA+CAB LA every 2
months compared to continuation of cART.
4.To assess viral resistance in participants
experiencing protocol-defined confirmed
virologic failure (plasma HIV-1 RNA ≥200
c/mL).
5.To assess the incidence of on-treatment
genotypic resistance to CAB, RPV and
other on-study cART up to Month 12 and
24.
 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Evaluation of the household-level impact of a single round of intermittent preventive treatment of malaria in schoolchildren: A randomized study
REFNo: HS1123ES

1. To determine the impact of intermittent preventive treatment of malaria in schoolchildren on malaria transmission at the household, as measured by the prevalence of parasitaemia at the household level.
2.To determine the impact of intermittent preventive treatment of malaria in schoolchildren on the health of the children as measured by the prevalence of parasitaemia among the children.

Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Cathy Green Louise
ID:
An Investigation into the Impact on Social Inclusion of High Volume Transport (HVT) Corridors and Potential Solutions to Identifying and Preventing Human Trafficking
REFNo: SS704ES

1. To investigate the role played by HVT corridors in human trafficking in Uganda and Tanzania;
2. To explore some of the factors (primarily transport-related and regulatory) that are contributing to human trafficking along HVT corridors (roads);
3. To assess the level of awareness of human trafficking and its impacts among transport providers, the users of HVT corridors, and the communities through which these routes pass;
4. To identify and recommend pilot innovations that can help recognise and counter human trafficking along HVT corridors.

 UK 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Beatrice Achan
ID:
Epidemiology of Invasive Fungal Diseases in Uganda
REFNo: HS1127ES

1. Estimate the prevalence of fungemia due to Candida, Cryptococcus and Aspergillus species.
2. Describe the host and environmental factors associated with fungemia.
3. Determine the antifungal resistance profiles of the isolated fungal pathogens.
4. Determine the molecular ecology of Cryptococcus species causing cryptococcal meningitis.
5. Estimate the prevalence of mycetoma in Uganda.

 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Noble Banadda
ID:
Unlocking resilience benefits from African water resources (RESBEN)
REFNo: A112ES

1. To establish and develop the ARUA Water CoE as an effective, high performance, research hub & nodes network of African researchers & post graduate students
2.To establish a common intellectual grounding and poastgraduate supervision capabilities in complex social ecological systems and transdisciplinarity
3. To recognise the primary and secondary research strength
4. To locate the primary and secondary research strengths in relation to the SDGs
 Uganda 2021-02-24 2024-02-24 Agricultural Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 A phase II trial to describe the pharmacokinetics, safety and efficacy of pharmacogenetics-guided dosing of isoniazid in patients with HIV-associated TB
REFNo: HS1159ES

• To describe the pharmacokinetics of isoniazid, given at a higher dose (10mg/kg) among patients with fast or intermediate NAT2 acetylator status and a standard dose (5mg/kg) among patients with slow NAT2 acetylator status, among patients with HIV and drug sensitive TB.
• To investigate the safety of pharmacogenetically-determined isoniazid dosing among TB-HIV co-infected patients with drug sensitive TB.
• To explore the efficacy of isoniazid among TB-HIV co-infected patients with drug sensitive TB receiving pharmacogenetically-determined dosing, using pharmacokinetic – pharmacodynamic (PK-PD) models.

Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Olive Kobusingye Chifefe
ID:
Observational Studies on Helmet Use, Speeding, Seat-Belt and Child Restraint in Kampala, Uganda
REFNo: HS1178ES

Main objective:
To establish the prevalence of road traffic crash severity risk factors in Kampala city namely speed, use of helmet use, seat-belt use, and drink- driving to generate evidence that can be used to inform policy and implementation strategies to promote road safety.

Specific objectives:
1. To assess the prevalence of seat-belt use and child restraint use among car occupants in Kampala.
2. To determine the prevalence of helmet use among motorcyclists in Kampala
3. To establish the prevalence and extent of speeding in Kampala
4. To determine the level of drink-driving in Kampala


Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Karugahe Wilber
ID:
Identifying psychosocial impact of COVID-19 and promising practices for meeting the mental health and protection needs to SGBV of vulnerable populations during a protracted crisis in Kampala Slums
REFNo: SS721ES

1. Identification of psychosocial and mental health issues/problems for potential SGBV victims as a result of COVID-19 pandemic.
2. To examine the relationship that exists between psychosocial and mental health issues, Sexual Gender based violence and Coping strategies among potential SGBV victims.
3. Identify the coping strategies to help potential SGBV victims to improve their mental health, avoid prevent its occurrence or re-occurrence.

 Uganda 2021-02-24 2024-02-24 Social Science and Humanities Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 COVID-19 in people living with HIV: Evaluation of risk factors and outcomes in resource-limited settings
REFNo: HS1192ES

To characterize the clinical features and course of symptomatic COVID-19 in PLWH, described overall and by HIV and comorbid disease factors including pregnancy status
 Nigeria 2021-02-24 2024-02-24 Medical and Health Sciences Non-degree Award
Dorothy  Nalweyiso Irene
ID:
Enhancing Ugandan undergraduate healthcare students’ application of evidence into practice through the development and evaluation of an Evidence-Based Practice Education Package
REFNo: HS1246ES

The main objective of the study is to determine the impact of an Evidence Based Practice (EBP) educational Package on the knowledge, skills, attitudes and behavior among undergraduate healthcare students in Uganda.
Specific objectives of the study:
i) To assess of the current literature regarding the present approaches for teaching EBP among undergraduate healthcare students.
ii) To explore the views and experiences of lecturers regarding the training and use of EBP in health practice.
iii) To assess the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare students before implementation the educational package.
iv) To develop an Evidence Based Practice (EBP) educational package for Ugandan undergraduate health care professionals.
v) To implement an Evidence Based Practice educational package among undergraduate healthcare students at Makerere university college of health sciences
vi) To compare the perceived knowledge, skills, attitudes and behaviour of EBP among undergraduate healthcare professional students before and after implementation of the educational package

 Uganda 2021-02-24 2024-02-24 Medical and Health Sciences Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Ankle-Brachial Index Screening for Peripheral Artery Disease in Uganda: Building a Training Model and Exploring the Feasibility and Acceptability of Implementation Strategies, Version Date: September 30, 2020
REFNo: HS1028ES

General Objective;
The long-term goal of the project will be to provide insights into the barriers and facilitators of implementing PAD screening interventions in resource-poor settings. Early detection of subclinical cardiovascular disease—including PAD—may be a personalized and cost-effective way to reduce cardiovascular disease burden in low- and middle-income countries worldwide.

Specific aims;
-Assess knowledge of cardiovascular risk and subclinical disease
-Estimate the percentage of participants achieving competency in ABI screening techniques after receiving basic training
-Determine the perceived acceptability and feasibility of a PAD screening implementation strategy within the community


 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Obed Mugisha
ID:
USING REDUCED DOSES OF INTRAVENOUS NEOSTIGMINE/GLYCOPYRROLATE TO REDUCE ITS SIDE EFFECTS IN THE MANAGEMENT OF POST-DURAL PUNCTURE HEADACHE AT MBARARA REGIONAL REFERRAL HOSPITAL: A SINGLE-BLIND RANDOMIZED DOSE-FINDING STUDY
REFNo: HS1075ES

General Objective
To assess the role of Neostigmine/Glycopyrrolate combination dose reduction on the incidence of its associated side effects in the management of PDPH in obstetric post-operative patients at Mbarara Regional Referral Hospital.
Specific Objectives

1. To compare pain scores for PDPH in the three Neostigmine treatment groups (20, 10, and 5mcg/kg).
2. To compare the incidence of Neostigmine/Glycopyrrolate side effects in the standard dose group (20mcg/kg) with the reduced dose groups(10mcg/kg and 5mcg/kg).

 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Degree Award
Immaculate  Atukunda
ID: UNCST-2021-R013573
 WULIRA APP – OCCUPATIONAL HEARING LOSS AMONG INDUSTRIAL WORKERS IN KAMPALA, UGANDA.
REFNo: HS1237ES

1. To determine the prevalence of occupational hearing loss among workers in a steel and iron manufacturing industry in Kampala.
2. To assess the acceptability of using the Wulira App for hearing loss screening among workers in a steel and iron manufacturing industry.

 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 BASELINE ASSESSMENT FOR NUTRITION INTERVENTIONS IN PALORINYA REFUGEE SETTLEMENT, OBONGI DISTRICT
REFNo: HS1241ES

The overall aim of this baseline study will be to assess the current status of nutrition outcomes, infant and young child feeding (IYCF) and livelihoods indicators among children and WRA, household food security and selected livelihood indicators among refugee households in Palorinya Refugee Settlement.

Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Tim Colbourn
ID:
How does a multi-country, multilateral network focused on specific health care improvements evolve and what shapes its ability to achieve its goals?
REFNo: SS659ES

1. To characterise how the QCN initiative was conceptualized and brought together, explore its aims and ethos and understand the global context in which QED arose

2. To explore how the QCN is enacted as a strategy for linking global and national actors

3. To explore case study countries’ contexts and capacities, their interactions with the global QCN and the effects this has on the emergence of the national QCN programme

4. To characterise strategies adopted in countries, their scale, scope and focus, mechanisms of action, the evolution of programmes and what influences them

5. To map the activities of the national programmes at district level and examine the approach to intervention

6. To examine which key data are collected to evaluate the effect of the QCN and assess any effects of network activities


 UK 2021-02-18 2024-02-18 Social Science and Humanities Non-degree Award
Charles Drago Kato Drago
ID: UNCST-2021-R012897
 Establishment of a Biomarker research facility to first track the development of COVID19 novel diagnostics and treatment alternatives in Uganda
REFNo: HS1096ES

1. To establish a biomarker research facility at Makerere University. (Here we shall add more equipment capacity to the existing BSL3 lab at COVAB to execute COVID19 research).
2. To identify and evaluate key SARS-CoV-2 biomarkers in saliva, urine and blood with diagnostic/prognostic or therapeutic potential.
3. To develop biomarker panels (single or multiple analytes) with diagnostic/prognostic or therapeutic potential.

Uganda 2021-02-18 2024-02-18 Medical and Health Sciences Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Mobile Phone enabled Diagnostics for Infectious Disease Diagnosis: Low Cost Tools for Digital Health in Uganda
REFNo: SIR50ES

I. Understanding Digital Health for Infectious Disease in Low Resource Settings
II. Understanding Data Integrity and Security in Digital Health in Africa;
III. Exploring the Relationship between Data and Healthcare Policy;
IV. ICT Devices for Data Acquisition and Communication in East Africa with a focus on Uganda;
V. Capacity Strengthening - Educational Training underpinning Mobile Health.

 Uganda 2021-02-18 2024-02-18 Engineering and Technology Non-degree Award
Christine Aanyu
ID:
Alarm and response systems for addressing maternal and perinatal deaths in Eastern Uganda. A case of re-activation of MPDSR
REFNo: HS635ES

1) To explore the factors that facilitate or constrain the implementation of the MPDSR protocols
2) To develop a collaborative innovation to address the constraints of implementing MPDSR protocols
3) To enhance system wide learning through documenting and sharing of best practices for implementing MPDSR protocols

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Paracetamol for Acute Renal Injury in Severe Malaria Trial (PARIST)
REFNo: HS965ES

1. To conduct pharmacokinetic studies of paracetamol in patients with acute kidney injury in severe malaria.
2. To assess the feasibility of conducting AKI in severe malaria in Eastern Uganda.
3. To conduct safety and preliminary effectiveness study for use of paracetamol in ameliorating AKI in severe malaria.

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Elizabeth Ekong Namukombe
ID:
Work-Based Learning for Baccalaureate Nurses in Uganda: Perception and Current Practice
REFNo: HS810ES

1. Explore the perception of baccalaureate nurses in Uganda on the ease of engaging in Work-based learning. 2. Explore the perception of baccalaureate nurses in Uganda on the usefulness of work-based learning. 3. Describe the current practice of Work-Based Learning among baccalaureate nurses in Uganda. 4. Determine any existing relationship between perceived usefulness and current practice of work-based learning among baccalaureate nurses in Uganda.
Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Jane Namagga Kasozi
ID:
HIV-Associated Neurocognitive Burden: Feasibility of Implementing International HIV Dementia Scale into a Nurse-led HIV Model at TASO centres in southwestern Uganda
REFNo: HS814ES

1.To determine the prevalence of HIV- associated neurocognitive disorders using IHDS among PLWH attending TASO centres in rural Southwestern Uganda.

2.To identify the risk factors associated with HIV- associated neurocognitive disorders among PLWH attending TASO centres in rural Southwestern Uganda.

3.To assess the impact of an education intervention on nurses’ knowledge and skills regarding the use of IHDS in screening and managing HIV- associated neurocognitive disorders

4.To explore nurses' perceptions towards screening and managing HIV- associated neurocognitive disorders using IHDS among HIV positive clients attending TASO centres in rural Southwestern Uganda.

5.To determine the feasibility of implementing IHDS into a nurse-led model of HIV care.

Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Andrew Ssemata
ID: UNCST-2023-R008259
 Exploring and understanding the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability in Sub Saharan Africa; a mixed methods study. (REMHAND)
REFNo: SS703ES

To explore and understand the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability and their significant others (siblings and parents) in Uganda.

Specific objectives
1. Explore and understand the life skills, sexual, reproductive and mental health needs among children and adolescents with disability.
2. Explore the SRH vulnerabilities, and experience (barriers and facilitators) to accessing SRH and mental health services.
3. Explore caregiver (parents and siblings) experiences and perspectives of the health implications of long‐term informal caregiving for children with SBH and disability.
4. Investigate the health, wellbeing and factors affecting the mental health of parents and siblings caring for children with disabilities.

 Uganda 2021-02-15 2024-02-15 Social Science and Humanities Non-degree Award
Bas van Boekholt
ID:
Turn-taking interactions in chimpanzees (Pan troglodytes schweinfurthii) in the wild
REFNo: NS153ES

To shed light on the evolution of language by providing the first systematic insights into the development of turn-taking in chimpanzees
 Netherlands 2021-02-15 2024-02-15 Natural Sciences Non-degree Award
Geoffrey Babughirana Babughirana
ID:
Effect of implementing the timed and targeted counselling (ttC) model on pregnancy outcome and Newborn survival in rural Uganda. A Quaisi experimental study in Hoima and Mansidi district
REFNo: HS574ES

To determine the effect of ttC on pregnancy outcomes and Newborn survival in Rural Uganda

1. To ascertain the extent to which ttC improves uptake of timely Goal Oriented ANC with a focus on the recommended 4 visits
2. To determine whether ttC contributes to the recommended hygienic birthing practices
3. To establish the extent to which ttC improves essential new-born care practices (ENC) during the new born period
4. To ascertain the extent to which ttC fosters positive male involvement in Pregnancy and New Born care
5. To ascertain the relationship between ttC implementation and appropriate pregnancy weight gain by end of Pregnancy.
6. To ascertain the relationship between ttC implementation and appropriate birth weight

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A5379: B-ENHANCEMENT OF HBV VACCINATION IN PERSONS LIVING WITH HIV (BEe-HIVe): Evaluation of HEPLISAV-B
REFNo: HS622ES

• To compare the week 12 seroprotection response (SPR) of a two-dose regimen of HEPLISAV-B (Group A, Arm 1) versus the week 28 SPR of a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in Hepatitis B virus (HBV) vaccine-experienced participants living with HIV (Group A).

• To compare the week 28 SPR of a three-dose regimen of HEPLISAV-B (Group A, Arm 2) versus a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in HBV vaccine-experienced participants living with HIV (Group A).

• To determine the week 28 SPR of a three-dose regimen of HEPLISAV-B in HBV vaccine-naïve participants living with HIV (Group B).

• To describe adverse events (AEs) reported in each study arm (Groups A and B, separately) over the duration of the study.


Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Clare Cheromoi -
ID:
Interrogating Political Corruption in Post-Independent Uganda: A Historical Perspective, 1962-2017.
REFNo: SS488ES

(1) To describe the transhistorical patterns and evolution of political corruption in Uganda between 1962 and 2017.
(2) To examine the political actors involved in the political corruption scandals experienced in post-independent Uganda.
(3) To explore the proximate and underlying causes of political corruption that are transhistorical in post-independent Uganda.
(4) To assess the transhistorical interrelationships between political corruption and anticorruption responses in post-independent Uganda.

Uganda 2021-02-12 2024-02-12 Social Science and Humanities Degree Award
Leonard Omadang
ID:
PREVALENCE, RISK FACTORS AND ECONOMIC IMPACT OF CYSTIC ECHINOCOCCOSIS IN LIVESTOCK HERDS AMONG THE PASTORAL AND AGRO-PASTORAL COMMUNITIES IN UGANDA
REFNo: A87ES

i. To determine the prevalence of Echinococcosis in livestock slaughtered in selected abattoirs in Uganda.

ii. To determine risk factors associated with cystic echinococcosis in livestock in selected pastoral and agro-pastoral communities in Uganda.

iii. To determine the economic losses of CE in livestock kept by the pastoral and agro-pastoral communities in Uganda.

 Uganda 2021-02-12 2024-02-12 Agricultural Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Implementation of a Quality Improvement Intervention to Improve Discharge Practices for Children recovering from Severe Infection Using a District model in Gulu and Rukungiri Districts
REFNo: HS926ES

The main objective in implementing this program is to improve patient outcomes for children recovering from Severe Infection though implementation of a multi-faceted quality improvement intervention targeting health workers, care givers and the community health workers.
Specifically we intend to :
1. Evaluate how a targeted behavior change intervention can affect health worker behaviors and facility readiness to assess and manage children during the discharge process.
2. To evaluate the effectiveness of a facility-based linkage to a community based follow-up system to improve post-discharge care for children recovering from severe infections

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Fred  Bulamba
ID: UNCST-2020-R014888
 The three delays model and Postpartum haemorrhage: a mixed-methods study at a teaching hospital in eastern Uganda
REFNo: HS932ES

Overall aim
The overall aims of this study are to understand how delays impact development of primary PPH (using the three-delays model) and how available preventive and therapeutic interventions are administered.

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Janet Lewis I
ID:
Reducing Prejudice Against Refugees Pilot
REFNo: SS662ES

The vast majority (85%) of the world’s political refugees live in developing countries, according to UNHCR. As of early 2019, Uganda was home to over one million refugees from South Sudan, and had the largest refugee/asylum-seeker population in Africa (ACCORD 2019). Uganda has a strong national commitment to hosting refugees that is reflected in its immigration policies, leading some to call it a “melting pot” of regional nationalities. Still, its population faces challenges absorbing these refugees that are common to host countries. Relations are often strained between the refugee population and Ugandans, some of who perceive refugees as unwelcome competition for local resources and services (World Vision 2018; UNHCR 2018; ACCORD 2019).
This study will allow us to better understand the perceptions of Ugandans towards South Sudanese refugees, and measure both the extent of anti-refugee prejudice there and whether a perspective-taking intervention is effective at reducing prejudice. This knowledge will be crucial for understanding how best to design a later, larger study, which could substantially advance knowledge about prejudice reduction towards refugees in Uganda.
Furthermore, this study will provide a useful indication about whether our full version of this study will be able to measure spillover of the treatment through social networks; we will ask respondents in our endline survey about whether and with whom respondents discussed the intervention. Prejudicial attitudes are socially reinforced; changing one person’s mind may be difficult if that person’s peers still hold prejudicial beliefs. Likewise, if many of one’s peers have begun to reconsider their own prejudices, one may be encouraged to do so as well. Our prior work leads us to expect the information to spread widely, and some change in attitudes and behavior, but only for those connected to a treatment recipient via certain kinds of social ties (Larson and Lewis 2017, 2018). Practitioners often assume that interventions spread from a subset of individuals to their broader community through felicitous spillovers. If this pilot is successful, our full study will be among the first to measure whether and how this occurs for prejudice reduction through networks. This knowledge could, among other things, lead to more efficient designs of community prejudice-reduction projects. Moreover, even if spillover effects are not present, the full study will be able to detect how news of the intervention spreads through local networks. Doing so will provide rare, direct evidence of information dissemination through word-of-mouth networks, which is useful for the design of programs aimed at seeding any type of public service message – from news intended to diffuse conflicts, to information about a new technology that promises to better hold politicians accountable or improve public health.

Our pilot study therefore addresses four questions:
(1) What is the extent of anti-refugee prejudice among Ugandans living in villages in West Nile?
(2) Do positions towards refugees correlate with their positions in village social networks?
(3) Can a brief conversation oriented towards taking the perspective of South Sudanese refugees reduce Ugandans’ prejudice toward them? If so, does the effect persist after 2-3 weeks?
(4) To what extent does news spread about this perspective-taking exercise, and through which types of contacts?
 USA 2021-02-12 2024-02-12 Social Science and Humanities Non-degree Award
AGGREY DHABANGI
ID:
Hemolytic Disease of the Newborn in Uganda: Burden and Clinical Characteristics (Short title: HDN in Uganda)
REFNo: HS1089ES

To determine the prevalence of HDN due to RhD among newborn infants with jaundice admitted to Kawempe National Referral hospital in Uganda.
 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 PREVALENCE AND RISKS ASSOCIATED WITH METABOLIC SYNDROME IN CHILDREN AND ADOLESCENTS LIVING WITH HIV IN UGANDA. A PILOT STUDY
REFNo: HS1128ES

i To determine the prevalence of MetS among children and adolescents living with HIV in Uganda.
ii To identify risks factors for the development of MetS in children and adolescents living with HIV.

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Abner Tagoola
ID:
A phase 2b study to Evaluate the safety and efficacy of IMR-687 in subjects with sickle cell disease.
REFNo: HS1092ES

1. To evaluate the fetal Hb (Hbf) response to IMR-687 versus placable.

2. To evaluate of IMR-687 versus placable
 Uganda 2021-02-11 2024-02-11 Medical and Health Sciences Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
 A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease
REFNo: HS1150ES

Objectives:
Primary Objectives
• To evaluate the fetal hemoglobin (HbF) response to IMR-687 versus placebo
• To evaluate the safety of IMR-687 versus placebo Seconduy Efficacy Objectives
• To evaluate the effect of IMR-687 versus placebo on HbF-associated biomarkers
• To evaluate the effect ofIMR-687 versus placebo on indices of red cell hemolysis
• To evaluate the effect ofIMR-687 versus placebo on indices of white blood cell (WBC) adhesion
To evaluate the effect of IMR-687 versus placebo on the incidence of vaso-occlusive crises (vocs)
• To evaluate the effect of IMR-687 versus placebo on quality of life measures Pharmacokinetic•Óbjectives
• To evaluate the PK ofIMR-687 and any major circulating metabolites
Exploratory Efficacy Objectives
To evaluate the effect of IMR-687 versus placebo on changes in red blood cell (RBC) characteristics and total Hb e To evaluate the effect of IMR-687 versus placebo on renal function
• To evaluate the effect of IMR-687 versus placebo on indices associated with cardiovascular pathophysiology and ischemic stroke risk

 Uganda 2021-02-11 2024-02-11 Medical and Health Sciences Non-degree Award
Casim Tolo Umba
ID: UNCST-2021-R012658
 Action Towards Reducing Aquatic snail-borne Parasitic diseases (ATRAP)
REFNo: NS128ES

The main objective of the project is to improve Health through the prevention and mitigation of risks that originate at the interface between humans, animals and the environment. In this project we want to increase the capacity to prevent infections by snail-borne diseases in western Uganda. The strategic objectives are as follows:
1. To strengthen scientific research capacity.
2. To strengthen physical and virtual diffusion of scientific research
results to the larger scientific community
3. To raise awareness about snail borne diseases to the general public.
4. To support good governance, based on the scientific results.
5. To develop synergies and complementary activities among partners through multi-partner governance and coordination


 Uganda 2021-02-10 2024-02-10 Natural Sciences Degree Award
MIRIAM NAKALEMBE
ID: UNCST-2019-R000824
 Designing and Piloting of a Mobile-based Transport Technology linking Mothers to Health Facilities to Reduce Maternal and New-born Deaths in Uganda during the COVID-19 Pandemic.
REFNo: HS1148ES

1. To identify the existing automated maternal services apps and assess the extent to which they provide near real-time information and communication between mothers and the transporters at community level.
2. To develop a mobile-based transport technology that improves two-way communication between mothers and the transporters at community levels
3. To pilot the mobile-based transport technology for its usability and acceptability

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."

NRIMS