Munezero Jonasi
ID: UNCST-2025-R023113
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ELUCIDATING THE THERAPEUTIC POTENTIAL OF Markhamia lutea ETHANOLIC AND AQUEOUS EXTRACTS IN A TESTOSTERONE-INDUCED RAT MODEL OF BENIGN PROSTATIC HYPERPLASIA
REFNo: NS1315ES
Main Objective
To elucidate the therapeutic potential of Markhamia lutea ethanolic and aqueous extracts in a testosterone-induced rat model of benign prostatic hyperplasia
Specific objectives
The specific objectives of this study are to:
1.Determine the phytochemical compounds of Markhamia lutea ethanolic and aqueous extracts using liquid chromatography-mass spectrometry
2. Determine the safety of the aqueous and ethanolic bark extracts of Markhamia lutea in testosterone-induced rat model of benign prostatic hyperplasia (BPH) using biochemical tests, hematological and histopathological examination of tissues
3. Assess the therapeutic efficacy of the aqueous and ethanolic bark extracts of Markhamia lutea in testosterone-induced rat model of Benign Prostatic Hyperplasia (BPH) using oxidative, hormonal, and inflammatory markers
4. Elucidate the mechanism of action of the identified bioactive compound using Androgen Receptor (AR) and 5α-Reductase (SRD5A2) proteins.
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Uganda |
2026-07-24 8:27:19 |
2029-07-24 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Peter Kisaakye
ID:
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Co-designing Health Innovations to reach Mobile Men with Co-Morbidities in Uganda
REFNo: HS8036ES
Building on promising approaches to men’s health in sub-Saharan African countries, the HIMM project aims to co-design and validate the feasibility of an intervention to improve men’s access to care for NCD-ID co-morbidity within mobility contexts. Our objectives and research questions are:
1. To explore the spaces, mobility patterns, actors, and livelihood assets shaping men’s access to care for NCD-ID co-morbidities in urban settlements and border towns
RQ1: What social, spatial, and infrastructural factors shape men’s mobility cycles, and how do livelihood assets along these cycles influence health-seeking for NCD-ID co-morbidities?
2. To assess the burden of diabetes, hypertension, and HIV among mobile men and their reported access to screening and treatment
RQ2: What is the burden of diabetes, hypertension, and HIV among mobile men and what are the associations between patterns of mobility and self-reported co-morbidities with clinical assessments of diabetes, hypertension, and HIV?
3. To examine how the evolving agenda on NCD-ID integration is being implemented at the health systems and services level, and experienced by mobile men
RQ3: How responsive are evolving NCD-ID integration policies to men’s mobility in Uganda?
4. To adapt promising strategies for delivering health care services to men for NCD-ID co-morbidities among mobile men
RQ4: How can co-design methodologies be adapted to engage mobile men in developing interventions for their unmet NCD/ID care needs?
5. To validate the feasibility and acceptability of the co-designed intervention and explore contextual factors likely to affect implementation and engagement.
RQ5: What is the perceived feasibility and acceptability of a co-designed intervention to improve access to NCD/ID screening and care for mobile men and what contextual factors are likely to influence implementation and engagement with the intervention?
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Uganda |
2026-07-24 8:25:43 |
2029-07-24 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Rukundo vicent
ID: UNCST-2025-R023088
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TERPENOID QUANTIFICATION AND PRODUCT FORMULATION FROM AERIALPARTS OF
AMARANTHUS VIRIDIS FOR THE MANAGEMENT OF SITOPHILUS ZEAMAIS
REFNo: NS1254ES
i. To isolate triterpenoids from aerial parts of A. viridis extracts.
ii. To determine the insecticidal repellency of the isolated triterpenoids against S. zeamais.
iii. To determine the composition and quantity of triterpenoids from aerial parts of A. viridis.
iv. To characterize the chemical structure of the isolated triterpenoids for repelling S. zeamais.
v. To formulate a product using the isolated triterpenoids for the management of S. zeamais.
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Uganda |
2026-07-24 8:02:57 |
2029-07-24 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Alfred Yayi
ID: UNCST-2025-R019850
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Prevalence, Attitudes, and Use of Complementary and Alternative Medicine (CAM) Among Medical Doctors in Asia and Africa.
REFNo: HS7686ES
1.To survey CAM use among Medical Doctors in selected hospitals in Asia and Africa.
2.To investigate Medical Doctors’ attitudes toward CAM in both regions.
3.To examine Medical Doctors’ perceptions of CAM safety, effectiveness, and clinical utility.
4.To compare cross-regional differences in CAM use and predictors of Medical Doctors recommendation.
5.To explore how Medical Doctors’ perceptions and attitudes influence their communication with patients regarding CAM.
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Uganda |
2026-07-24 8:01:37 |
2029-07-24 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Kemigisha Grace
ID:
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Determinants of malaria vaccine acceptability in a pre-introduction setting: A Baseline study among caregivers in Mpererwe, Kawempe Division, Kampala District.
REFNo: HS7730ES
The main objective is to assess the determinants of malaria vaccine acceptability among children’s caregivers in Mpererwe Parish, Kawempe Division, Kampala District.
Specific objectives
1. To evaluate the level of knowledge regarding the malaria vaccine among caregivers in a pre-introduction setting.
2. To determine the prevalence of vaccine acceptability (behavioural intent) among caregivers before the commencement of the immunisation programme.
3. To explore the perceived barriers and facilitators that influence a caregiver's decision to accept a prospective malaria vaccine.
4. To identify factors associated with the acceptability of malaria vaccine among the child caregivers in Mpererwe Parish.
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Uganda |
2026-07-24 7:55:53 |
2029-07-24 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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