Robert Odendi Gideon
ID: UNCST-2024-R002130
|
MENTAL HEALTH CHALLENGES, ADVERSE CHILDHOOD EXPERIENCES
AND INTERPERSONAL PSYCHOTHERAPY AMONG ADOLESCENTS AT KAMPIRINGISA
NATIONAL REHABILITATION CENTER, CENTRAL UGANDA
REFNo: HS5763ES
1. To determine the prevalence of mental health challenges (Depression, PTSD, and alcohol substance use disorders) and adverse childhood experiences (ACEs) among adolescents at Kampiringisa National Rehabilitation Centre (KNRC).
2. To examine the relationship between ACEs and mental health challenges, with social support as a mediator among adolescents at KNRC.
3. To explore the experiences and perceptions of adolescents regarding the effectiveness of existing counseling practices in reducing depressive symptoms among adolescents at KNRC.
4. To identify the socio-cultural factors, institutional policies, and individual characteristics that influence the feasibility, acceptability, and effectiveness of Group Interpersonal Therapy (Group IPT) in reducing depressive symptoms at KNRC.
5. To evaluate adolescents' experiences and perceptions of the feasibility, acceptability, and effectiveness of Group IPT compared to the existing counseling practices at KNRC.
|
Uganda |
2025-04-02 10:00:01 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Felix Bongomin
ID: UNCST-2020-R014224
|
Chronic Pulmonary Aspergillosis: Optimization of Therapy, Immunogenetic Screening, and Diagnosis in Uganda [CPA_OPTIONS_Phase I: A Prospective Cohort Study]
REFNo: HS5799ES
The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,
|
Uganda |
2025-04-01 17:44:43 |
2028-04-01 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
|
The Integrated Management of Chronic Lung Illnesses in Uganda
REFNo: HS5728ES
Aim 1: To determine the prevalence of and factors associated with chronic respiratory illnesses e.g., asthma, chronic obstructive pulmonary disease among presumptive TB patients who test negative for TB on GeneXpert testing
Aim 2: (a) To determine the prevalence of, factors associated with post TB lung disease (PTLD) among patients who complete TB treatment (b) To determine the effect of post TB lung care on health related QoL among patients with PTLD
Aim 3: To determine barriers and facilitators for linkage to treatment for patients referred for chronic lung care
Aim 4: To document the cost per asthma/COPD case found during integrated community-based screening.
|
Uganda |
2025-04-01 17:31:43 |
2028-04-01 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
george paasi
ID: UNCST-2020-R014619
|
THE CLINICAL SPECTRUM, GEOSPATIAL DISTRIBUTION AND GENETIC MODIFIERS OF SEVERE MALARIA AMONG CHILDREN WITH SICKLE CELL DISEASE IN EASTERN UGANDA.
REFNo: HS5714ES
i) To determine the effect of host RBC polymorphisms on the risk and severity of malaria.
ii) To determine the Geospatio-temporal distribution of the malaria-sickle cell disease syndemic in Uganda.
iii) To determine the clinical spectrum of severe malaria among children with SCA in eastern Uganda.
|
Uganda |
2025-04-01 17:21:57 |
2028-04-01 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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|
ERICK SSEGUJJA
ID: UNCST-2021-R012964
|
Partnerships for Stronger Knowledge Systems in Africa (KNOSA): Lessons from Uganda
REFNo: HS5716ES
Specifically, the implementation research has the following objectives;
1. To characterise the nature and functioning of the different components of the current national knowledge system, ??with a focus on the health sector.
2. To explore constraints and challenges affecting the capacity of Uganda’s national knowledge systems.
3. To document and assess the current interventions to strengthen the national knowledge system?
4. To explore opportunities for strengthening the capacity of the national knowledge system to advance evidence-informed decision making in Uganda’s health sector.
|
Uganda |
2025-03-25 11:14:05 |
2028-03-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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|
Ronald Moses Galiwango
ID: UNCST-2024-R015239
|
INTEGRATED FEMALE SEXUALLY TRANSMITTED INFECTION TESTING FOR HIV EPIDEMIC CONTROL THROUGH PREP (IN-STEP)
REFNo: HS5715ES
a) To conduct an individually randomized effectiveness implementation trial of SRST plus cSTI testing to increase PrEP use among African women at high HIV risk.
b) To perform a mixed-methods, implementation science evaluation of female cSTI testing for improving PrEP use for HIV prevention.
c) To determine the most efficient, population-level female cSTI testing strategies to reduce HIV incidence in African settings.
|
Uganda |
2025-03-25 11:13:20 |
2028-03-25 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Prudence Beinamaryo
ID: UNCST-2023-R007239
|
Developing a robust interdisciplinary-informed WASH framework for the prevention and elimination of the wicked public-health problem of schistosomiasis (WickedSchisto)
REFNo: HS5707ES
I. What are the true health, economic and societal impacts of schistosomiasis?
a) Characterise what quality of life means to individuals living in Schistosoma endemic areas in Cameroon and Uganda, and how this is affected by infections, WASH access, environmental, spatial, social and other determinants.
b) Measure the diverse impact of schistosomiasis on individual’s and household’s quality of life.
c) Quantify the economic costs associated with schistosomiasis to individuals and society.
d) Develop and validate a field-suitable morbidity marker for mapping and monitoring disease resolution.
II. What are the most cost-effective combinations of WASH and MDA interventions?
a) Test the hypothesis that MDA refusal, due to fear of side effects, is linked with latrine access.
b) Characterise relative contributions of existing WASH on reducing reinfection post MDA: risk to self.
c) Quantify environmental force-of-infection and the impact of ‘risk to self’ and ‘risk to
|
Uganda |
2025-03-25 11:11:44 |
2028-03-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Riley Derby Nicholas
ID: UNCST-2025-R017680
|
Impacts of early social life on social and physical development in mountain gorillas
REFNo: NS946ES
Study social and physical change in immature mountain gorillas in Bwindi Impenetrable National Park, in collaboration with Bwindi Gorilla Project, through combining behavioral, hormonal, and non-invasive growth measures
|
USA |
2025-03-25 11:02:11 |
2028-03-25 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Erika Sininärhi
ID: UNCST-2025-R017295
|
Physiological correlates of variation in personality traits in the banded
mongoose Mungos mungo
REFNo: NS942ES
1) To determine the relationship between social rank, prenatal androgen exposure, and personality.
2) To investigate whether individual differences in facial thermal patterns are connected to personality, behaviour and stress reactivity.
|
Finland |
2025-03-25 11:01:27 |
2028-03-25 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
David Hayman T. S.
ID: UNCST-2023-R006403
|
One Health, multiple factors: an interdisciplinary investigation of emerging infectious disease
REFNo: NS924ES
Infectious diseases significantly impact global health, affecting both humans and animals. Zoonotic diseases, which are transmitted between animals and humans, pose particular risks in regions with high human-wildlife interaction. One such region is Uganda, specifically around Bwindi Impenetrable National Park (BINP), where communities live in close proximity to domestic and wild animals.
The objectives of this research are to:
Identify and quantify zoonotic pathogens in fecal samples from various animal species.
Assess pathogen prevalence across different species.
Analyze microbial community structures and antimicrobial resistance genes.
|
New Zealand |
2025-03-25 11:00:19 |
2028-03-25 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
|
Using patient journey mapping approach to understand and improve post-abortion care within routine health care services
REFNo: HS4137ES
General objective
The general objective of this study is to use a journey mapping approach to understand client experiences as they navigate abortion services, and gaps in services, in order to improve PAC service delivery, client experiences and outcomes within the health care system.
Specific objectives
The specific objectives of the journey mapping approach include:
1. To document client experiences at different stages of post-abortion care-seeking.
2. To understand the current service provision processes for clients seeking post-abortion care services and identify gaps and unmet needs in these services.
3. To evaluate comprehensiveness of care and identify interventions to improve care.
4. To compare patient experiences with established standards of care
The specific objectives of the survey include:
1. To characterize the type and range of contraceptive and abortion-care services available for women who seek care at health facilities.
2. To determine whether women, including young women, receive comprehensive counseling on choices related to manual vacuum aspiration (MVA), medical abortion (MA) and contraception and which factors are related to receipt of such counselling.
3. To determine whether family planning and abortion services are provided with respect and compassion.
|
Uganda |
2025-03-25 10:56:04 |
2028-03-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Karen Bailey M.
ID: UNCST-2024-R003544
|
Understanding invisible socio-environmental systems through pesticides across human-wildlife interactions
REFNo: SS3710ES
To model simulations of the interactions within the SES, illustrating the feedback mechanisms between pesticide use, environmental changes, and human-wildlife well-being,To quantify pesticide exposure and associated health outcomes in humans and wildlife, with a focus on spatial and temporal trends,To assess socio-economic and environmental factors influencing farmers\' decisions regarding pesticide use,To investigate the socio-environmental drivers and molecular-level impacts of pesticide use in a tropical forest-agricultural mosaic and develop strategies that balance agricultural productivity with biodiversity conservation among communities around the Kibale National Park ,
|
USA |
2025-03-25 10:53:06 |
2028-03-25 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Kamya Moses
ID: UNCST-2020-R014203
|
Integrating management of alcohol use, intimate partner violence, and menopausal transition into HIV care for women living with HIV in Uganda
REFNo: HS5750ES
To explore the unique health challenges faced by women living with HIV in Uganda related to intimate partner violence, menopausal transition, and alcohol use disorder (AUD), focusing on distinct age groups to inform targeted health interventions
|
Uganda |
2025-03-19 13:02:04 |
2028-03-19 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Abel Kakuru
ID: UNCST-2022-R009193
|
Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5638ES
To estimate the site-specific IR of P. falciparum infection by rapid diagnostic test (RDT) testing, overall and by age group (5-11 years, 12-17 years, 18-60 years) during the active detection of infection period.
|
Uganda |
2025-03-19 12:57:39 |
2028-03-19 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Noeline Nakasujja
ID: UNCST-2019-R001428
|
Clonal Hematopoiesis: A Global Perspective on the Impact of CH on Alzheimer’s Disease in Sub-Saharan Africa
REFNo: HS5533ES
Main Objective
1. The aim of this proposed work is to compare the frequency and type of clonal hematopoiesis (CH) mutations in age-matched African American and Ugandan populations. We intend to determine the correlation between specific CH-associated mutations and development of Alzheimer’s Disease in both a Ugandan and African-American population.
Specific Objectives
1. Compare the frequency of CH in an elderly African American versus elderly Ugandan population.
2. Compare the types of CH mutations in an elderly African American versus elderly Ugandan population.
3. Determine the correlation between specific CH-associated mutations and the development of AD in a Ugandan population.
|
Uganda |
2025-03-19 12:53:37 |
2028-03-19 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
STEVEN SEBBALE
ID: UNCST-2023-R006063
|
PARTICIPATION OF FEMALE DOCTORATE HOLDERS IN SCIENCE, TECHNOLOGY AND INNOVATION: AN EXAMINATION ON GENDER EQUITY, INCLUSIVITY AND INTERSECTIONALITY IN UGANDA
REFNo: SS3712ES
a) To examine the demographic and professional characteristics of female doctorate holders in Uganda
b) To assess the intersectional challenges faced by female doctorate holders in Uganda
c) To provide data-driven insights for integrating intersectionality into UNCST’s grants system
|
Uganda |
2025-03-18 13:09:22 |
2028-03-18 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Richard Wismayer
ID: UNCST-2019-R000483
|
The microbiome as an aetiological factors in colorectal carcinoma in Ugandan patients
REFNo: HS5644ES
1. To investigate the frequency of carriage of faecal P. micra in Ugandan CRC patients and controls by 16S rRNA sequencing and PCR and assess its potential as a non- invasive biomarker compared to other bacteria (Study 1).
2. To explore the associations of P.micra and F.nucleatum, the general tumour microbiome, the intra-tumour immune response and the tumour MSI status within the tumour itself. P.micra and F.nucleatum will be determined by PCR, the tumour microbiome by 16S rRNA sequencing and the tumour immune response both pathologically and by the numbers of infiltrating lymphocytes a key prognostic marker. MSI and MSS status will also be identified (Study 2).
3. To analyse the bacterial content of faeces using 16S rRNA sequencing in relation to the clinical features and MSI/MSS status of CRC in Ugandan patients and controls using network analysis in Ugandan patients. To identify bacteria positively and negatively associated with Ugandan bowel cancer carriage (Study 3).
4. To determine the prevalence of cancer related stool toxins, pks, FadA, and ETBF in Ugandan colorectal cancer patients and controls using quantitative PCR assays on faeces (Study 4).
5. To compare the above findings with those of CRC patients and controls from the international microbiome network in Ghana, India, Vietnam, Argentina and England (Study 5).
|
Malta |
2025-03-18 13:03:54 |
2028-03-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Shahiid Kiyaga
ID: UNCST-2021-R007055
|
Genetic Diversity and Transmission Intensity Heterogeneity of Plasmodium falciparum in Malaria Endemic Regions in Uganda
REFNo: HS5697ES
General Objective
To analyze the genetic diversity of P. falciparum and the heterogeneity in malaria transmission intensity in high-endemic areas of Uganda.
Specific Objectives
1. To assess the genetic diversity and population substructure of P. falciparum in high endemic areas of Uganda by quantifying allelic variation and estimating population structure parameters using F_ST (fixation index) and principal component analysis (PCA).
2. To characterize the heterogeneity in transmission intensity in high endemic areas of Uganda using P. falciparum targeted amplicon genomic data and malaria epidemiological parameters.
3. To develop and apply advanced machine learning models to predict geographical origins of P. falciparum parasites in Uganda using whole-genome sequence data.
|
Uganda |
2025-03-14 19:14:47 |
2028-03-14 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Racheal Ninsiima
ID: UNCST-2020-R014564
|
Effect of blockchain technology on the performance of barley farmers in eastern Uganda
REFNo: A536ES
i) To determine farmers’ behavioural intention to accept BCT in Uganda’s eastern barley producing region.
ii) To examine the factors that influence adoption and extent of use of BCT among barley farmers in eastern Uganda.
iii) To determine the effect of BCT on barley farmers’ productivity and gross margin in eastern Uganda
iv) To develop suitable BCT implementation framework among barley farmers in eastern Uganda.
|
Uganda |
2025-03-14 19:13:35 |
2028-03-14 |
Agricultural Sciences |
Non-Clinical Trial |
Degree Award |
|
Bruce Kirenga J
ID: UNCST-2019-R001460
|
SURVEY, SAFETY AND EFFICACY OF HERBAL PRODUCTS USED FOR MALARIA PROPHYLAXIS AND TREATMENT IN UGANDA.
REFNo: HS5468ES
To conduct a survey of herbal medicinal products used for malaria prophylaxis and treatment, evaluate their safety and prophylactic efficacy among school-age children (8-15yrs) in Kibuku district, Uganda.
1. To identify herbal medicinal products used by communities for malaria prophylaxis and treatment in Uganda.
2. To evaluate the artemisinin content of herbal medicinal products used by communities for malaria prophylaxis and treatment in Uganda.
3. To determine the antiplasmodial activity (IC50) of herbal medicinal products used for malaria prophylaxis and treatment in Uganda.
4. To evaluate the safety of herbal medicinal products used for malaria prophylaxis among school age children (8-15 years) in Kibuku district in eastern Uganda.
5. To determine malaria incidence among school age children (8-15 years) receiving selected herbal medicinal products for malaria prophylaxis compared to monthly Dihydroartemisinin-Piperaquine (DP) in Kibuku district in eastern Uganda.
6. To determine prevalence of parasitaemia among school age children (8-15 years) receiving selected herbal medicinal products for malaria prophylaxis compared to monthly Dihydroartemisinin-Piperaquine (DP) in Kibuku in eastern Uganda.
|
Uganda |
2025-03-14 19:08:33 |
2028-03-14 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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