Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eugene Ruzagira
ID: UNCST-2023-R008282
 Extended monitoring of HIV status and vaccine-induced seropositivity among PrEPVacc trial participants (PrEPVacc Extension Study).
REFNo: HS7676ES

1. To provide comprehensive HIV testing and counseling services to PrEPVacc trial participants, including virus detection and prevention of the misdiagnosis of HIV infection among individuals with VISP.
2. To facilitate and support participants who wish to take up PrEP to reduce their risk of acquiring HIV.
3. To facilitate linkage to care for participants who acquire HIV and support their timely initiation of antiretroviral therapy.
4. To explore participants’ and trial staff’s reflections on trial participation and outcomes, including their lived experiences of VISP and perceptions of oral PrEP offered within the trial.

Uganda 2026-06-01 18:05:24 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur Sekiziyivu
ID: UNCST-2026-R023989
 EVALUATION of HEALTH CARE WORKERS’ ADHERENCE to MALARIA CASE MANAGEMENT GUIDELINES (HAMG) IN MAYUGE DISTRICT.
REFNo: HS7648ES

Aim 1: To assess HCWs’ adherence to the 2023 UCG in the treatment of patients with confirmed uncomplicated malaria at Mayuge HC IV for the three months preceding this study, and the facility-level factors that influence adherence. Aim 2: To explore behavioural determinants of HCWs’ adherence to the 2023 UCG in the treatment of uncomplicated malaria at Mayuge Health Centre IV. Aim 3: To develop an implementation strategy aimed at improving HCWs’ adherence to the 2023 UCG in the treatment of uncomplicated malaria in Mayuge District.
Uganda 2026-05-28 17:53:46 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Ainembabazi Hebert
ID: UNCST-2026-R024520
 Reducing Food Loss and Waste of Fruits and Vegetables in Uganda’s Food Markets
REFNo: A760ES

Reduce post harvest losses of fruits and vegetables among retail traders in Kampala markets through access to cold storage services
 Uganda 2026-05-28 16:53:16 2029-05-28 Agricultural Sciences Non-Clinical Trial Non-degree Award
Gertrude Nakigozi
ID: UNCST-2025-R022719
 The Many faces of Trauma and Recovery around the World: Mapping Experiences in Cultural Context (Matrix) Pilot Study
REFNo: HS7621ES

1. Assess the cultural relevance, feasibility and acceptability of the study design and instruments (survey and in-depth interview questionnaire) to inform implementation feasibility in Phase II of the project. 2. Preliminarily explore cross-cultural experiences of traumatic events, including individual psychological and somatic responses to PTEs, their perceived causes, approaches to coping and healing, subjective wellbeing and functioning, and the role of culture, context and identity. 3. Identify cross-cultural conceptualizations and expressions of trauma, including convergences and divergences in traumatic experiences, trauma sequelae, idioms of distress, and cultural scripts, their subjective interpretation and the meaning attributed to these. 4. Investigate culturally-specific healing and coping strategies, including individualistic vs collective approaches.
Uganda 2026-05-28 16:43:56 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 UCatchUp cost-effectiveness evaluation
REFNo: SS5226ES

Understand the potential to scale up the UCatchUp program,
 Uganda 2026-05-28 16:42:20 2029-05-28 Social Science and Humanities Non-degree Award
Florence Kyoheirwe Muhanguzi
ID: UNCST-2021-R002777
 Climate Resilience Solutions in the West Nile Region of Uganda (CARIS)
REFNo: SS5142ES

The primary objective of CARIS is to investigate the complex interplay of hydrological, ecological, and socioeconomic factors in the West Nile region of Uganda, focusing on the Enyau River catchment within the context of climate change.
Uganda 2026-05-28 16:39:51 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Namulema Edith
ID:
Exploring the feasibility and safety of using the ‘LeVe Neonatal CPAP System’ to assist neonates with signs of respiratory distress at Mengo Hospital
REFNo: HS7747ES

1) Feasibility Objective - To determine the proportion of neonates in whom the LeVe CPAP device can be successfully initiated and maintained for the entire study duration.
2) Safety Objective - To determine the incidence of CPAP-related adverse events occurring within the first 7 days of CPAP therapy.
3) Respiratory Effectiveness Objective - To assess the early respiratory response to CPAP within 2 hours of initiation and for the entire study duration using SpO?, FiO? measures and the Silverman-Andersen respiratory distress score.
4) Prematurity-Related Outcome Objective - To determine the incidence of survival to discharge, bronchopulmonary dysplasia, and retinopathy of prematurity.
5) To explore healthcare workers' perceptions and experiences regarding CPAP training adequacy, their confidence in using neonatal CPAP, and their views on how CPAP implementation influences neonatal respiratory outcomes within their clinical setting

 Uganda 2026-05-28 16:35:26 2029-05-28 Medical and Health Sciences Clinical Trial Non-degree Award
Martin Bakunda
ID: UNCST-2025-R022360
 FINANCIAL LITERACY AND FINANCIAL WELLBEING A MODERATED MEDIATED RELATIONSHIP OF SOCIAL CAPITAL AND FINANCIAL STRESS AMONG MICRO AND SMALL BUSINESS OWNERS IN KAMPALA, UGANDA
REFNo: SS5363ES

I. To examine the effect of Financial Literacy on Financial Wellbeing II. To determine the effect of Financial Stress on Financial Wellbeing III. To assess the effect of Social Capital on Financial Wellbeing IV. To examine the effect of Financial Literacy on Financial Stress V. To examine the mediation effect of Financial Stress on the relationship between Financial Literacy and Financial wellbeing VI. To examine the moderating effect of social capital on the relationship between financial literacy and financial stress VII. To assess the moderating effect of social capital on relationship between financial literacy and financial wellbeing VIII. To examine the moderating effect of social capital on the relationship between financial stress and financial wellbeing IX. To analyze the moderation effect of social capital on the indirect relationship between financial literacy and financial wellbeing through financial stress
Uganda 2026-05-28 16:33:41 2029-05-28 Social Science and Humanities Degree Award
Elly Atuhumuza
ID: UNCST-2024-R002706
 Evaluating the Active Ingredients and Dose Response Effects of Group Interpersonal Psycho-therapy Components on Depression
REFNo: HS7468ES

1. To determine the comparative effectiveness of each core IPT-G component (psychoeducation, peer support, and problem-solving skills) in reducing depression symptoms (as measured by the PHQ-9) from baseline to post treatment, when delivered as a single session. 2. To determine feasibility and acceptability of each individual arm. 3. To assess the effect of session intensity (duration) on the efficacy of each core component by comparing outcomes across low, medium, and high intensity doses for a single session. 4. To evaluate the effect of treatment frequency (number of sessions) on the efficacy of each core component by comparing outcomes from a single session, 2, 4, and 6 sessions with enhanced treatment as usual. duration. 5. To identify interaction effects between the type of active ingredient, session intensity, and treatment frequency to determine if certain components benefit more from increased duration, increased number of sessions, or a specific combination of both. 6. To develop an optimized therapy model by synthesizing the findings to propose a stream- lined protocol that specifies the most potent components and their minimal effective dosage for reducing depression symptoms in low resource settings.
Uganda 2026-05-28 16:30:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Cust
ID: UNCST-2025-R021803
 Empirical Insights into the Real Cost of PEPFAR and USAID HIV Funding Cuts in sub-Saharan Africa
REFNo: SS4802ES

1) To assess the impact of the US budget cuts on HIV service provision and health outcomes in sub-Saharan Africa. 2) To assess the reallocation of resources through the change in relative service provision priorities following the US budget cuts.
 UK 2026-05-28 16:09:44 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
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