Pavel Reppo Aleksandrovich
ID:
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Implementing the MANAS trial in Uganda (MAN U) - The Pilot Phase
REFNo: HS134ES
Research Question & Specific Objectives
Question: How will implementing a trained Community Health Worker (CHW)-led Collaborative Stepped Care Intervention (CSCI) lead to an improvement in recovery from depression among patients within general outpatient attending public primary care facilities in Uganda?
Aim 1: To determine whether treatment from trained CHWs leads to 1) patient recovery from MDD as defined by the DSM-IV at 6 months, and 2) the proportion of patients with above threshold scores (PHQ-9 score of ≥10). Hypothesis: Constituents of collaborative care interventions predicted a favorable outcome.
Aim 2: To increase awareness of CHW-led, collaborative stepped care as a viable option of treatment for depression among trainees, study participants, the community and stakeholders. Relevance: Community views and input are essential to inform the development of a culturally appropriate training curriculum for CHWs.
Aim 3: To determine the outcome of the CHW training on retention of knowledge and skills in competencies required to deliver the stepped care intervention among trainees after the training. Hypothesis: Trained CHWs will demonstrate increased level of knowledge and skills in competencies required to deliver collaborative stepped care after the training.
Aim 4: To determine the perceptions of CHWs, study participants, the community and stakeholders towards the process of integrating CHW-led, collaborative stepped care into community based mental healthcare. Relevance: There is a need to understand the views of participants and stakeholders pre and post to determine project efficacy.
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USA |
2017-10-31 |
2020-10-31 |
Medical and Health Sciences |
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Non-degree Award |
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Anaclet Namanya Mutiba
ID:
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Teachers' Understanding and Classroom Practices of Quality Education in Ugandan Primary Education: A Case of Bushenyi District
REFNo: SS124ES
The main study objective is to find out how teachers understand and practice quality education in Ugandan primary education.
The specific objectives are:
(i) To find out how teachers understand neoliberal policies in relation to quality education.
(ii) To establish how teaching and instruction processes reflect quality education.
(iii) To find out factors that influence teaching and instructional processes and methodology.
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Uganda |
2017-10-31 |
2020-10-31 |
Social Science and Humanities |
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Degree Award |
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KOHJUN HORI
ID:
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Land use and Soil erosion in high populated region in southwestern Uganda
REFNo: A21ES
The area of southwestern Uganda lies along the border with Rwanda and is characterized by high population density, despite the fact that it is a rural area. The area is a highland ranging in altitude from 1,200 to 2,350 m. People have been forced to use limited areas of farmland because of the population increase. In the slope areas of this Area, the shapes of the crop fields are irregular depending on the landform. This feature exacerbates soil loss and agricultural production. There is a high risk of collapse of embankment due to heavy rain. In the previous study, it is pointed out using questionnaire survey as a measure to prevent soil erosion carried out by local residents, but it is not clear by investigate scientifically that the usefulness to prevent soil erosion possessed by terrace farming. It is suggested that soil degradation is accelerating due to short fallow and sudden heavy rain due to climate change. It is expected that the population increase will continue in the future, and it will be necessary to prepare the environment that can sustain livelihood even in the situation of decreasing the per capita area of farm land. Therefore, I will clarify in detail the natural environment aspects that have a big influence on the livelihood activities of the local residents and verify the land use form of the local residents. In discussing soil erosion in mountainous regions of Africa, it is essential to verify sustainable land use that can withstand the effects of climate change. In this study, scientific verification of soil erosion possessed by terrace farming will be carried out in the mountainous area in southwestern Uganda, where land shortage and soil deterioration become serious. Finally I devise a method of land use to prevent soil degradation and aim to improve residents' livelihoods. This research is composed of three main research.
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Japan |
2017-10-31 |
2020-10-31 |
Agricultural Sciences |
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Degree Award |
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Adrian Muwonge
ID:
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The dynamics of antimicrobial resistance (AMR) genes in the pig and human gut microbiome in Uganda
REFNo: HS103ES
The hypothesis to be tested is that people in contact with pigs in peri-urban settings are at higher risk of acquiring AMR genes across this interface than people in rural settings.
The specific objectives are:
1. To identify significant changes in taxonomic and AMR genes in gut microbiomes of people and their pigs in peri urban and rural settings over a one-year period using 16SrRNA, AMR gene probes and real time PCR.
2. To conduct forensic investigations of the significant changes detected in objective 1 using sequence based metagenomics on the corresponding gut microbiomes in parallel with whole genome sequencing and phenotypic AMR testing of sentinel bacteria to understand the underlying dynamics.
3. To predict, estimate and make inferences on AMR gene occurrence, taxa-linked within and between host exchange and their potential phenotypic effects using bioinformatic, statistical and support vector machine approaches on the data generated in 1&2.
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Uganda |
2017-10-11 |
2020-10-11 |
Medical and Health Sciences |
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Non-degree Award |
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Gladys Tugume T
ID:
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Predictors and Outcomes of patients lost to follow-up from HIV care and treatment in Uganda
REFNo: HS130ES
1. To describe outcomes (HIV-related &other death, self-transfers and disengaged from care) of PLHIV LTFU from HIV care and treatment.
2. To describe the change in cumulative incidence of mortality, retention and ART initiation of HIV-infected patients in Pre-ART care after incorporating outcomes of LTFU patients.
3. To describe the change in cumulative incidence of mortality and retention of HIV-infected patients on ART after incorporating outcomes of LTFU patients.
4. To determine predictors of loss to follow-up among PLHIV in HIV care and treatment at Jinja, Lira, Mubende RRH’s.
5. To determine reasons for engagement or disengagement from HIV care and treatment
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Uganda |
2017-10-11 |
2020-10-11 |
Medical and Health Sciences |
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Non-degree Award |
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Sylvester Onzivua
ID:
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Postmortem study on patients with neuropsychiatric manifestations of unknown etiology, nodding syndrome, and other forms of epilepsy who died in Gulu, Kitgum, Lamwo and Pader
REFNo: HS64ES
• Use postmortem examination to determine cause of death in a selected study population.
• Use histopathology to describe the post-mortem findings of individuals who die of neuropsychiatric manifestations of unknown origin, NS and other forms of epilepsy in villages with high epilepsy prevalence in Gulu, Kitgum, Lamwo and Pader.
• Use histopathology to investigate whether Ov microfilariae are able to penetrate the brain by evaluating histologic tissue for the products of Ov microfilariae
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Uganda |
2017-10-03 |
2020-10-03 |
Medical and Health Sciences |
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Non-degree Award |
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othiniel musana mambya
ID: UNCST-2019-R001339
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Prospective, Single Arm, Pivotal Clinical Trial Designed to Assess the Safety and Effectiveness of the InPress Device In Treating Primary Postpartum Hemorrhage
REFNo: HS92ES
Evaluate the safety and effectiveness of the InPress Device in the control and reduction of primary postpartum hemorrhage.
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Uganda |
2017-10-03 |
2020-10-03 |
Medical and Health Sciences |
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Non-degree Award |
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Christopher Mayanja Samuel
ID:
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Leadership and Gender: Exploring female students’ lived experiences in leadership in Ugandan public University Councils
REFNo: SS117ES
The main research question of the study is: What are the lived leadership experiences of female student leaders who are members of public university councils in Uganda?
1. Who are female student leaders participating in public university councils in Uganda?
2. How do female student leaders who participate in public university councils in Uganda experience their relations with other council members?
3. What challenges (if any) do female student leaders face on public university councils in Uganda?
4. What lessons can be drawn about gender and leadership from the experiences of female student leaders participating in public university councils in Uganda?
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Uganda |
2017-10-03 |
2020-10-03 |
Social Science and Humanities |
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Degree Award |
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Moses Kamya R
ID:
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Cohort and entomology studies to estimate longitudinal changes in malaria metrics in Nagongera, Uganda
REFNo: HS119ES
Objectives of epidemiology studies
1. To estimate the incidence of malaria, parasite prevalence, and the molecular force of infection among cohort study participants.
2. To characterize factors determining the malarial force of infection.
3. To determine factors affecting the duration, density, and clinical consequences of blood stage malaria infection.
4. To assess the associations between overnight travel and the risk of malaria infection.
5. To estimate measures of transmission intensity including the human biting rate, sporozoite rate, and the entomological inoculation rate at the household level.
6. To characterize the species composition of mosquito vectors and the host source of mosquito blood meals.
Objectives of transmission studies
7. To characterize factors associated with gametocyte production.
8. To evaluate the impacts of human, parasite, and mosquito factors on parasite infectivity to mosquito vectors.
9. To characterize the human infectious reservoir for malaria.
Objectives of immunology studies
10. To measure antibody responses to malaria antigens and associations between antibodies responses and protection from /exposure to infection with malaria parasites.
11. To characterize malaria specific cellular immune responses in naturally exposed children and adults.
Objectives of resistance studies
12. To assess the impact of genotypic markers of antimalarial drug resistance on malaria transmission.
13. To assess the impact of genotypic markers of insecticide resistance on malaria transmission.
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Uganda |
2017-09-29 |
2020-09-29 |
Medical and Health Sciences |
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Non-degree Award |
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Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
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The Link Between Tuberculosis Infection and Type-2 Diabetes Mellitus: Contribution of Innate Lymphoid Cells
REFNo: HS66ES
Primary objective: To investigate the exposure prevalence of latent and active tuberculosis among newly diagnosed type 2 diabetes mellitus (T2DM) patients attending the diabetic clinic at Mulago National Referral Hospital (MNRH)-Kiruddu, compared to healthy non diabetic community controls in Kampala, Uganda
Nested Secondary objective: To assess the frequency of innate lymphoid cells (ILCs), T-helper (Th)17, Th1 cells, and immune responses among T2DM patients.
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Uganda |
2017-09-26 |
2020-09-26 |
Medical and Health Sciences |
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Non-degree Award |
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