Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Simon  Okongo
ID:
PREVALENCE, ASSOCIATED FACTORS, AND CUTANEOUS EFFECTS OF SKIN LIGHTENING AMONG PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL SKIN CLINIC. RefNO: SS1867ES
REFNo: SS1867ES

To determine the cutaneous effects of skin lightening among MRRH skin clinic patients. ,To identify the factors associated with skin lightening among MRRH skin clinic patients.,To establish the prevalence of skin lightening among MRRH skin clinic patients.,To establish the prevalence, the associated factors, and cutaneous effects of skin lightening among MRRH skin clinic patients.,
 Uganda 2023-08-07 15:22:35 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Juliet Namukasa
ID:
Low-carbon Mobility in Kampala: User perspectives and practices on walking, cycling and public transport.
REFNo: SS1921ES

The following research questions will be addressed: i. What factors have influenced the adoption and non-adoption of low-carbon mobility transport modes by Kampala’s every day travelers? Who is adopting what (choice of modes), how frequently and why? ii. Is there an enabling environment that supports adoption and implementation of low-carbon mobility modes of transport? How are new infrastructures connected to these mobility modes and domesticated? iii. What strategies should be in place to support more widespread usage of low-carbon mobility modes of transport (including shared solutions) and how can the middle class be encouraged to use mass transportation modes? iv. What is the potential of e-mobility being introduced in Uganda to replace the fossil fuelled vehicles?
 Uganda 2023-08-07 15:21:03 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
 A phase 2, partially-blinded, randomised trial assessing the safety and efficacy of TBAJ876 or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis
REFNo: HS2928ES

The objectives of the trial are to evaluate the efficacy, safety, and tolerability of TBAJ876 (3 doses) or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, smear-positive pulmonary DS-TB in comparison to the SOC
 Uganda 2023-08-07 15:20:08 2026-08-07 Medical and Health Sciences Clinical Trial Non-degree Award
Kamada Lwere
ID: UNCST-2022-R009359
 GUT MICROBIOME COMPOSITION, IMMUNE RESPONSE, AND GENETIC PREDISPOSITION TO ALZHEIMER’S DISEASE AND RELATED DEMENTIA IN A UGANDAN POPULATION.
REFNo: HS2930ES

1. To conduct a systematic review of the gut microbiome composition of individuals with Alzheimer’s disease and related dementia. 2. To determine the composition of the gut microbiome and compare individuals with ADRD and their controls. 3. To determine the levels of proinflammatory cytokines and compare individuals with ADRD and their controls. 4. To determine the distribution of ApoE (ApoE2, ApoE3 and ApoE4 variants) and ABCA7(Premature termination codon (PTC) mutations) and Presenilin (PSEN 1, 2 mutations) and compare individuals with ADRD and their controls.
Uganda 2023-08-07 15:12:16 2026-08-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Ephraim Kisangala
ID:
Preferences, value and impact of informal caregivers in the management of chronic diseases in sub-Saharan Africa (SSA)
REFNo: SS1846ES

• To examine the health and economic impact of caregiving on informal caregivers (ICGS) of patients with chronic diseases in sub-Saharan Africa • To understand the factors ICGs consider when making a decision to provide care to a person with a chronic disease in SSA. • To explore how providing informal care affects the lives of informal caregivers. • To determine the most important factors in the decision to provide informal care. • To estimate the monetary value of providing informal care to patients with chronic diseases.
Uganda 2023-08-07 15:04:16 2026-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
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