Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Henry Mugerwa
ID: UNCST-2019-R000420
PLATINUM: A multi-part, multi-center PLATform study to assess the efficacy, safety, tolerability and pharmacokinetics of anti-malarial agents administered as monotherapy at multiple dose levels and/or combination therapy IN patients with Uncomplicated Plasmodium falciparum Malaria
REFNo: HS2748ES

Main Objectives:
1. Part A: To assess the parasite clearance time (PCT) of oral doses of an anti- malarial agent administered as monotherapy in patients with uncomplicated P. falciparum malaria
2. Part B: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as combination therapy versus the standard of care (SoC) in patients with uncomplicated P. falciparum malaria

Secondary Objectives
1. Part A: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as monotherapy in patients with uncomplicated P. falciparum malaria
2. Part B: To assess the parasite clearance time (PCT) of oral combinations of anti-malarial agents versus SoC in patients with uncomplicated P. falciparum malaria
3. To characterize PK of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy [Part B] in patients with uncomplicated P. falciparum malaria
4. To assess the safety and tolerability of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy versus SoC [Part B] in patients with uncomplicated P. falciparum malaria
Uganda 2023-08-10 13:49:44 2026-08-10 Medical and Health Sciences Clinical Trial Non-degree Award
ANITA MUHAIRWE
ID:
CORPORATE GOVERNANCE ROLES AND EMPLOYEE SATISFACTION IN HIGHER EDUCATION INSTITUTIONS: A CASE OF SELECTED PRIVATE UNIVERSITIES IN UGANDA
REFNo: NS618ES

iii. To assess the effect of corporate governance roles on employee satisfaction in selected private universities in Uganda ,ii. To analyze the contribution of work environment to employee satisfaction in selected private universities in Uganda.,i. To assess the relationship of corporate governance roles and work environment in selected private universities in Uganda. ,
Uganda 2023-08-08 15:05:06 2026-08-08 Natural Sciences Non-Clinical Trial Degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
Assessing the effect of mealworm consumption and production on nutrition and health status of children in refugee and host communities in Western Uganda, a Refugee Insect Production For Food and Feed ( RefIPro) Project
REFNo: HS3071ES

D. To assess child anthropometrics/growth and dietary intake over 6 months in preparation for a mealworm-based school meal intervention study,C. To develop a nutritious school meal enhanced with mealworm and with high acceptability among the target group of school children,B. To assess the progress of building the capacity for scaling up mealworm production including identifying local feed substrate and assess the implementation processes in the local context ,A. To assess barriers and drivers among key stakeholders (farmers, farmers associations, school heads/teachers/parents/children) of mealworm consumption and production for sale ,Improving nutrition and health of refugee and host community children through the production of mealworm,
Uganda 2023-08-08 12:45:34 2026-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Effect of an interactive SMS system in improving the reporting of adverse drug reactions among people living with HIV in Tanzania and Uganda: a randomized controlled trial: The REMIND ADR TRIAL
REFNo: HS2922ES


To investigate the effectiveness of SMS reminders on improving ADR reporting compared to no SMS among people living with HIV in Tanzania and Kampala Uganda.
To describe the most commonly reported ADR profiles among people living with HIV in Tanzania and Uganda.
To determine the most common routes/ methods of reporting ADR used by PLHIV.
To explore the causal relationship between the commonly reported ADRs and ART.
To improve treatment options for participants who reported ADR.
To explore the technical feasibility and acceptability of the intervention in reporting ADR among PLHIV.

Uganda 2023-08-08 12:42:32 2026-08-08 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE)
REFNo: HS2703ES

Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE) is a master protocol being conducted in many countries around the world, and funded by the National Institutes of Health, USA. STRIVE will evaluate the safety and effectiveness of unlicensed and licensed treatments and different combinations of treatments, to improve the health outcomes of adults
hospitalised with acute respiratory infections, like COVID-19 or influenza.
Uganda 2023-08-08 12:39:21 2026-08-08 Medical and Health Sciences Clinical Trial Non-degree Award
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