Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
CHARLES LUGERO
ID:
A global registry to study the demographics, socioeconomic and clinical factors, etiologies, pathophysiology, management, barriers to care, and outcomes of heart failure patients
REFNo: HS144ES

Study 1. Estimate the incident rate of outcomes in HF patients in world Objectives regions and overall, and assess social and lifestyle factors (demographics, socioeconomic variables, clinical risk factors, diet, medication use, and health‐related quality of life), etiologies and variations in treatment patterns that might influence mortality and morbidity. 2. Describe determinants of different HF phenotypes (HFpEF, HFrEF, HF due to valvular disease, ALVD) in these world regions, and their management and outcomes. G‐CHF Protocol Page 3 2016‐09‐26 Version 1.2 3. Describe the potential role of biomarkers (BNP/NT‐proBNP and troponin, as available), related genetic determinants, and their relation to clinical factors, treatments, and type of HF 4. Assess non‐cardiac co‐morbidities at enrolment, their incidence during the study and how they influence outcomes from both cardiovascular and non‐cardiovascular mortality and morbidity. 5. In a sub‐study of approximately 4000‐5000 patients, perform measures of frailty, cognitive and lung function, mental health, adherence to medication, and dietary assessment, with collection of blood and urine samples for central analysis, to further understand the pathophysiologic changes in HF and their relation to outcomes. 6. Describe patient and system barriers to HF care in a global HF population.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Clémence Bonneaud
ID:
Pant-hoot call in immature chimpanzees
REFNo: NS40ES

We will describe the age at which pant-hoot production starts. We will examine the order in which the four phases of the pant-hoot call develop. For example: is development sequential with the order of the final pant-hoot call, or do later phases (the climax) develop before early ones. We will investigate at what point multiple elements are produced within a call, and whether the sex differences seen in the pant-hoot calls of adults are also seen during development.
France 2018-04-04 2021-04-04 Natural Sciences Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Clinical and genetic factors influencing variability in warfarin dose requirements in Sub-Saharan African patients: An observational study
REFNo: HS164ES

1. To determine demographic and clinical factors that determine individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care 2. To identify ethnic-specific genetic factors influencing individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care
UK 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Agnes Kiragga
ID:
Locating disengaged HIV positive women on Option B+ and ascertainment of outcomes among their infants
REFNo: HS175ES

1. To describe the pregnancy outcomes and HIV care status among women (and their exposed infants) who initiate Option B+ 2. To correct 6 week and 18 month estimates of MTCT through tracing of a random sample of HIV positive women who initiated Option B+ during pregnancy and disengaged from care. 3. To identify factors associated with HIV sero-positivity among infants born to women initiated on Option B+. 4. To establish the frequency of Multiclass Resistance among HIV positive infants born to women initiated on Option B+ 5. To estimate the proportion of disengaged women with viral failure and correct estimates of viral suppression (3 rd UN 90 goal) in the facilities.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
ANNET MAGOLO KISAKA
ID:
INFLUENCE OF ORGANISATIONAL CULTURE ON EMPLOYEE PERFORMANCE IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS155ES

1. To examine the extent to which organizational mission influences employee performance in public Universities in Uganda 2.To assess the extent to which consistency affects employee performance in public Universities in Uganda 3. To establish how employee involvement influences performance in public universities
Uganda 2018-04-04 2021-04-04 Social Science and Humanities Degree Award
Erik Serrao
ID:
A Clinical Study to Validate the Accuracy and Usability of HemoTypeSCTM, Which is a Novel, Low-Cost, Rapid Diagnostic Test for Sickle Cell Disease
REFNo: HS158ES

The objective of this evaluation protocol is to determine the clinical accuracy of HemoTypeSC in diagnosing SCD-relevant Hb phenotypes (A/A, A/S, A/C, S/S, S/C, and C/C) as compared to “gold standard” HPLC/IEF laboratory testing methodology.
USA 2018-03-27 2021-03-27 Medical and Health Sciences Non-degree Award
Richard Batamwita
ID:
Utilization of obulamu interventions by sex workers and men who have sex with men: a retrospective analysis of services delivery data.
REFNo: HS189ES

To determine changes in the levels of utilization of HIV and STI services by MSM and FSW before and after OBULAMU campaign in Uganda and to compare their utilisation levels with those of the general population (non-MSM and non-FSW population).
Uganda 2018-03-27 2021-03-27 Medical and Health Sciences Non-degree Award
CORDELIA MBOIJANA KATUREEBE
ID:
Developing and Validating a Pediatric and Adolescent HIV Testing Eligibility Screening Tool for Health Care Providers in Uganda
REFNo: HS155ES

General Objective 1) To develop, validate and field test a Pediatric and Adolescent HIV Testing Eligibility Screening Tool (PATEST) for use in outpatient departments within health facilities in Uganda Specific Objectives 1) To develop a Pediatric and Adolescent HIV Testing Eligibility Screening Tool (PATEST) for use in outpatient departments within health facilities in Uganda. 2) To determine the sensitivity, specificity, positive predictive value and negative predictive value of the PATEST among individuals aged 18 months to 19 years in selected study health facilities in Uganda. 3) To assess the perceptions and experiences of use of the PATETST among health care workers, caregivers and adolescents attending outpatient departments within selected study health facilities in Uganda.
Uganda 2018-03-15 2021-03-15 Medical and Health Sciences Non-degree Award
Joanne Corbin Nancy
ID:
Effects of armed conflict and displacement on men's socio-cultural and economic roles in northern Uganda
REFNo: SS119ES

• To examine the impact of armed conflict and internal displacement on men’s socio-cultural and economic roles in Northern Uganda. • To examine this phenomenon from subjective experiences. • To explore the adaptations that men have made to deal with any socio-cultural and economic impacts from armed conflict and internal displacement. • To disseminate the findings from this study in appropriate venues as recommended by Ugandan colleagues and produce an article on the results of this research.
USA 2018-03-14 2021-03-14 Social Science and Humanities Non-degree Award
Innocent Besigye Kabahena
ID: UNCST-2019-R001025
Identifying gaps in screening, diagnosis, clinical practice guidelines and improving hypertension management in primary care facilities in Tororo District
REFNo: HS176ES

1. To identify the gaps in the health facility minimum requirements for successful screening, diagnosis and management of hypertension in Tororo district primary care facilities. 2. To establish the gap between hypertension management guidelines and clinical practice in Tororo district primary care facilities 3. To describe what needs to change for improved care of hypertension in primary care facilities in Tororo District.
Uganda 2018-03-14 2021-03-14 Medical and Health Sciences Non-degree Award
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