Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,299
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
John William Okello
ID: UNCST-2024-R004558
 Learning Entrepreneurship and Agriculture Practically - LEAP Programme
REFNo: SS3039ES

The longitudinal follow-up study will measure and analyse the self-efficacy in teaching of agriculture and entrepreneurship student-teachers/instructors and newly qualified teachers/instructors (NQTs/NQIs) over time – in particular, their self-efficacy in using gender responsive project-based learning (PBL), study and career guidance (SCG) and, in the case of instructors also work-based learning (WBL) (internships) in collaboration with the agri-WoW. This is one of the core outcomes of LEAP interventions with NTC Mubende, NTC Unyama, NICA and Gulu University related to their school practice and industrial training trajectories. Besides self-efficacy, career commitment to teaching will also be measured, to explore its’ interplays with self-efficacy.,
 Uganda 2024-09-10 12:36:56 2027-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mutiu Bakare Mutiu
ID: UNCST-2024-R004123
 AN OPTIMIZED ANFIS WITH GENE EXPRESSION PROGRAMMING BASED DEMAND SIDE ENERGY MANAGEMENT CONTROLLER WITH GRID AND SOLAR PV/BATTERY ENERGY SOURCES
REFNo: SIR393ES

V. To compare and validate the models developed in II and III using ANFIS and HOMER software.,IV. Assessment of the optimal system configuration to determine the techno-economic analysis to quantify Solar PV to save the cost of Energy of the proposed system configuration.,III. To develop a GEP-ANFIS energy management scheme for operation of industrial loads while ensuring maximum user comfort without waiting time;,II. To use (GEP-ANFIS) model and historical load data to accurately forecast the energy consumption and renewable energy generation;,I. To integrate MPPT Algorithms into the system design,The aim of this research is to examine the potential of applying optimization-based TOU DSM in the industrial sector by utilizing grid-connected solar and battery energy sources to reduce peak electricity demands as well as the costs associated with annual electricity consumption,
 Nigeria 2024-09-10 11:07:47 2027-09-10 Engineering and Technology Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Assessing the reliability and test performance of malaria rapid diagnostic tests after expiration.
REFNo: HS4760ES

AIM 1: Estimate the reliability, defined as the proportion of malaria RDTs that function (i.e., appearance of control band) at various time-points up to one year after expiration. AIM 2: Determine the test performance (e.g., sensitivity, specificity) of malaria RDTs for the diagnosis of P. falciparum malaria at various time-points up to one year after expiration compared to non-expired RDTs and routine light microscopy performed in parallel. AIM 3: Estimate the time-to-negativity after treatment among participants with a positive RDT on enrollment.,The primary objective of the proposed project is to evaluate the performance of malaria RDTs at various states of expiration (e.g., 1-, 2-, 3-months post-expiration) compared to non-expired RDTs in routine use. If our hypothesis is correct, our results may facilitate (i) use beyond the stated expiration and/or production of RDTs with longer expiration periods, both of which could reduce medical waste. ,
 Uganda 2024-09-10 11:02:24 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MICHAEL KAWOOYA GRACE
ID: UNCST-2020-R014672
 The African Breast Imaging Dataset for Equitable Cancer Care (The ABreast Data set)
REFNo: HS4709ES

1. To train community health workers to conduct breast examination using hand held ultrasound machines in the community
2. To develop the first publicly available expert-labelled ultrasound imaging data with mammograms, a wealth of clinical profiles, and where available biopsy pathology data.
3. Introduce the Abreast Challenge, as a new image segmentation grand challengevii at the 2024 Medical Image Computing and Computer Assisted Intervention Society (MICCAI) annual meeting, happening for the first time in Africa (Morocco).
4. Introduce a baseline state of the art (SOTA) model of a deep learning approach for lesion detection of breast lesions on low-cost (also low-resolution) POC-US for wider screening accessibility.
5. Train up to 70 African clinicians and researchers to develop SOTA ML lesion detection methods to ensure that SSA retains a local community of skilled experts who are knowledgeable on how to use ML data to solve local health needs.
 Uganda 2024-09-10 10:56:03 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 Evaluating the Impact of DESC Approach: Comparative Quasi-Experimental Study of Community Health Worker Performance in Moyo and Adjumani Districts, West Nile Uganda
REFNo: HS4756ES

1) To evaluate the impact of the DESC Approach on CHW performance metrics, including CHW reporting rates, household visits, health services provided, and engagement in activities.
2) To generate evidence on performance-based pay options to inform policies on CHW compensation at the district level by October 2024
3) To compare CHW performance between intervention (Moyo District) and non-intervention (Adjumani District) areas.
4) To assess the effectiveness of mobile technology utilization, training, and performance-based incentives in enhancing CHW performance.
 Uganda 2024-09-10 10:52:55 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDITH AWACORACH
ID:
GREEN FINANCE INCENTIVES AND SUSTAINABLE LIVELIHOOD OUTCOMES IN UGANDA
REFNo: SS2993ES

To examine the mediating role of competitive advantage of green charcoal value chain in the relationship between Green Finance incentives and sustainable Livelihood outcomes in Uganda,To examine the mediating roles of green charcoal value chain in the relationship between Green Finance incentives and sustainable livelihood outcomes of green charcoal production in Uganda.,To examine the competitiveness of green finance incentive for green charcoal in sustainable livelihood outcomes in Uganda,To assess the contributions of green finance incentives in the green charcoal value chain to enhance sustainable livelihood outcomes in Uganda.,To assess the green finance use in green charcoal production to enhance sustainable livelihood outcomes in Uganda,To assess availability and accessibility of green finance incentives and its contributions to sustainable livelihood outcomes in Uganda,
 Uganda 2024-09-10 10:49:52 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
 OBTAINING SINGLE-CELL LEVEL INSIGHTS INTO THE IMMUNOLOGICAL AND METABOLIC PATHWAYS ASSOCIATED WITH VACCINE HYPO-RESPONSIVENESS [REVERSE]
REFNo: HS4782ES

1. To measure the SARS-CoV-2 antibody response at baseline, 3 months after prime vaccination and 1 month after boost vaccination in European and Ugandan adults. 2. To characterise peripheral blood mononuclear cells (PBMCs) and their response to prime/booster vaccination with the AstraZeneca ChadOx1 nCoV-19 vaccine in European and Ugandan adults using single-cell technologies
UK 2024-09-10 10:45:15 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brandon Maser
ID: UNCST-2024-R005142
 Understanding How Policies, Politics, and National Contexts Influence Access to Opioid Medicines in Uganda
REFNo: HS4768ES

1) To elucidate the policy mechanisms that are used by policymakers to govern access to and safe use of opioid medicines in Uganda. 2) To understand how political factors and national context influence the political priority for improving access to opioid medicines within Uganda’s national government’s policy agenda. 3) To understand how political factors and national context influence how governmental, non-governmental, and transnational actors formulate alternative policy options for ensuring access to opioid medicines in Uganda. 4) To understand how policies governing opioid analgesics and those governing OAT have been uniquely influenced by political factors and national contexts during Uganda’s opioid policy reforms.
 Canada 2024-09-10 10:26:35 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Busiku
ID:
Validity, Feasibility and Acceptability of digital x-ray Computer Aided Diagnosis for Tuberculosis by Village Health Teams in Bududa District- a cross-sectional study
REFNo: HS4792ES

3. To determine the feasibility and acceptability of portable Digital Chest X-ray CAD4TB version 7 by VHTs in Bududa District.,2. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to ZN in Bududa District.,1. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to X-pert MTB/RIF (x-pert) in Bududa District.,To evaluate the diagnostic accuracy of portable CXR CAD4TB as Community TB diagnostic tool in Bududa District in Uganda.,
 Uganda 2024-09-10 10:17:27 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Peer-led Implementation of TB-HIV Education and Adherence Counselling in Uganda
REFNo: HS4801ES

To evaluate the implementation fidelity and context of a peer-navigation strategy for TB-EC to improve TB treatment and ART outcomes, To determine the feasibility, acceptability, and appropriateness of a peer-navigation strategy for TB-EC and explore the social-behavioral mechanisms for improving adherence and clinical outcomes. ,To evaluate the implementation of a peer-navigation strategy for TB-EC to improve TB treatment completion and ART retention. , To evaluate the effectiveness and implementation of a novel, peer-led TB education and counseling strategy to improve outcomes among persons with tuberculosis (TB) with and without HIV/AIDS and assess the social-behavioral mechanisms underlying the observed treatment effects. ,
 Uganda 2024-09-10 10:03:57 2027-09-10 Medical and Health Sciences Clinical Trial Non-degree Award
Okumu Tendo Ivan
ID:
Assessment and remediation of selected heavy metals contaminants in tannery wastewater from selected tanneries in Jinja city and Wakiso district,Uganda
REFNo: NS795ES

Prepare and characterize biochar using green banana peels and coffee husks ,Evaluate the concentration levels, speciation and toxicity of selected heavy metals( Cr,Cu,NI,Pb and Zn) in tannery wastewater.,To assess the concentration levels and to bioremediate selected heavy metals contaminants in tannery wastewaters from designated tanning industries in Uganda,
 Uganda 2024-09-10 10:01:32 2027-09-10 Natural Sciences Non-Clinical Trial Degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
 Community Development Intervention Strategies and Poverty Alleviation in Wakiso District
REFNo: SS3067ES

(iv) Explore how interactions among development actors affect poverty alleviation in Wakiso district,(iii) Assess if, and to what extent, multipurpose cooperative societies leverage community development intervention strategies in poverty alleviation in Wakiso District,(ii) Analyse the relationship, if any, between the various development strategies and the selected poverty outcomes (income, food security, household assets, agency),(i) Understand how the communities in Wakiso district perceive poverty and development,To generate, using a systems approach, more contextualized knowledge on the effects of skills acquisition, transfers and financial inclusion supported by non-governmental organisations through cooperatives on household income, assets, food security and agency. ,
 Uganda 2024-09-10 10:00:24 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Riccardo Durini
ID:
Comparison in sociality in snared and non-snared chimpanzees
REFNo: NS861ES

The goal is to analyse social behavioural differences between snared and healthy chimpanzee individuals. The comparison focuses on certain traits related to sociality, such as the number and quality of bonds with other individuals, party formation, grooming partners and others.
 Switzerland 2024-09-09 14:54:20 2027-09-09 Natural Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of the performance of HIV rapid diagnostic tests on Oral Fluid and Urine for WHO prequalification assessment.
REFNo: HS4871ES

To describe and assess the operational characteristics and ease of use of HIV RDTs on urine or oral fluids and its suitability for use in countries with limited infrastructure (no/limited electricity, no/limited clean water, and inadequate means of biosafety disposal).,To assess inter-reader variability (for subjectively read assays),To assess analytical performance of HIV RDTs for the detection of antibodies to HIV in oral fluid and urine: ● Sensitivity on seroconversion panels compared to a benchmark assay ● Performance on mixed-titer panels ● Subtype detection ● Lot-to-lot variation ,To determine the sensitivity and specificity of HIV RDTs for the detection of antibodies to HIV in oral fluids and urine as compared to a reference algorithm (two EIAs followed by a line immunoassay) in blood- derived specimen and compare them to predefined acceptance criteria for prequalification,The overall objective is to evaluate and compare the accuracy of HIV rapid tests for the detection of HIV antibodies in oral fluids and urine against established performance criteria. ,
 Uganda 2024-09-04 18:43:09 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY NUWA
ID: UNCST-2022-R011102
 Using behavioural insights to design a behavioural intervention to accelerate malaria mosquito net use in Uganda: The Be In A Net study
REFNo: SS3095ES

1. The aim of this study is to understand the behaviours, barriers, and facilitators affecting the use of insecticide-treated nets (ITNs) in selected areas of Uganda in order to develop a behavioural intervention to increase ITN use,To design and refine a behavioural intervention to increase mosquito net use based on behavioural science principles.,To conduct exploratory research to examine the role of psychological, cognitive, emotional, cultural and social factors impacting ITN use to inform the design of a behavioural intervention to encourage mosquito net use.,
 Uganda 2024-09-04 18:41:43 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
molly naisanga
ID: UNCST-2023-R005602
 Mental Health and Psychosocial Support Services for Refugee Children and Adolescents with HIV in West Nile Uganda.
REFNo: HS4486ES

2. To explore experiences with available mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda.,1. To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda,To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda and to explore their experiences with available mental health and psychosocial support services.,
 Uganda 2024-09-04 13:33:35 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olak Ongaya Denis
ID:
Scaling-up innovative Gender, Inclusion and Safeguarding Approaches: Evidence from Malawi, Uganda and Ethiopia
REFNo: SS2919ES

• Strengthen capacities of education managers at all levels to identify and address bottlenecks in the delivery of equitable and quality education at the school level.,• To Mobilize knowledge on optimal use of school-based data for education decision-making, policy and management amongst education stakeholders.,• To gather and develop guidelines on best practices of scale-up, which will be adopted and resourced by the government to develop capacity, influence, and improve education policy and practice on scale-up of GEI interventions,• To generate knowledge that contributes to a broader understanding of the factors of scale-up to guide stakeholders, including policymakers and other researchers on future GEI education interventions and scale-up strategies. ,To contribute to the understanding and improvement of scale-up practices of GEI-focused education projects at local, regional, and international levels.,
 Uganda 2024-09-04 12:57:16 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Katende
ID:
Characterization of New Childhood HIV Infections in USAID supported regions in Uganda (NCHiS)
REFNo: HS4857ES

The assessment aims to characterize those children newly diagnosed with HIV in terms of their demographics, geography, access to care, care continuum and social determinants, to inform child HIV services on targeted and effective case finding and treatment services that can support the reversal of sub-optimal case finding and viral load suppression, and the stagnation in the overall rate of new vertical infections.
a. Primary objective
To describe the determinants or associated risk factors of persisting vertical HIV infections among children.
b. Secondary objectives
i. To report on the perspectives of key stakeholders on the utilization of child HIV services from implementor to the recipient.
ii. To describe the distribution of HIV seropositive children by HIV acquisition mode e.g., vertical MTCT (PMTCT and non-PMTCT), BF, through sex, trauma/GBV.
iii. To establish the proportion of uniquely identified HIV seropositive children in the survey region.

 Uganda 2024-09-04 11:10:19 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Understanding the causes of deaths amongst persons with Rheumatic Heart Disease in Uganda
REFNo: HS4663ES

Main objective: To identify the causes of death among RHD registrants in the National RHD registry in Uganda
 Uganda 2024-09-02 15:12:28 2027-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Babirekere Iriso
ID: UNCST-2024-R005372
 International Investigation into the Genetics of Severe Acute Malnutrition in Children
REFNo: HS4569ES

Determine the contributions of genetic markers to the development of ESAM vs NESAM and its clinical characteristics Elucidate the role of epigenetic mechanisms in the development of ESAM vs NESAM
 Uganda 2024-08-30 15:11:38 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS