Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
Promoting education and child well-being through the Education for Protection and Well-being model in Sironko and Budaka districts, Uganda: A cluster non-randomised controlled trial (EPW – Study)
REFNo: HS6277ES

4.1 General Objective
The purpose of this study is to assess the effectiveness of the EPW Program on children, caregivers, and teachers.
4.2 Specific Objectives
1. To assess the effectiveness of the EPW program by comparing intervention and control schools in terms of Student social-emotional learning (SEL) practices, Caregiver-child relationships and positive parenting practices and Teachers’ positive classroom management practices
2. To assess the prevalence of secondary outcomes for each participant group
3. To determine implementation factors (e.g., attendance, fidelity) that influence program effectiveness.
4. To establish the level of satisfaction, barriers and facilitators to participation in the program up to endline in intervention group.
Uganda 2025-11-07 5:10:34 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Caroline Agabiirwe Noel
ID: UNCST-2025-R020394
Development and effectiveness of the Better Health media campaign on maternal and child health-seeking behaviours in Uganda.
REFNo: HS6737ES

1. To explore the knowledge, attitudes, and practices among the target audiences related to ANC, PNC, malaria vaccine and diarrhoea management in children. 2. Assess the acceptability of the campaign among the target audience, exploring attitudes of the target audience towards the campaign and mechanisms of campaign impact. 3. Run a controlled quantitative evaluation study to assess the impact of the campaign on knowledge, beliefs, intentions and behaviours related to ANC, PNC and malaria vaccine. 4. To complement the quantitative study with controlled time series analysis of routine DHIS2 data, to examine shifts in trends in treatment seeking, ANC uptake, PNC uptake, and malaria vaccine uptake that may be attributable to the campaign.
Uganda 2025-11-07 5:08:21 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
VICTORIA NYAITEERA
ID: UNCST-2021-R011699
Knowledge, attitudes, practices, and moderators of Competency Based Medical Education: A needs assessment and faculty development in CBME delivery at Mbarara University of Science and Technology
REFNo: HS4973ES

5. To suggest appropriate adjustments to curricula implementation process for fidelity improvement.,4. To determine the moderators (facilitators and barriers) of competency based medical training in post graduate programs,3. To train the faculty involved in postgraduate medical training on CBME implementation.,2. To identify MUST FOM faculty development/training needs for successful CBME implementation.,1. To assess the knowledge attitudes and practices of faculty towards competency-based training in medical post graduate programs at MUST,To improve the fidelity of competency based medical training curricula for postgraduates at MUST by training the faculty in CBME delivery and making faculty training in CBME a MUST institutional priority.,
Uganda 2025-11-07 5:06:17 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Igaga Namugaya
ID: UNCST-2022-R011354
Advancing Health and Leadership: A Wellbeing Toolkit for Women in Anesthesia and Surgery in Uganda
REFNo: HS6633ES

General Objective To determine the state of wellbeing among the women in the Anesthesia and Surgical Specialties in Uganda Specific Objectives To understand how women in the Anesthesia and Surgical Specialties in Uganda define wellbeing. To determine the state of well-being among women in the Anesthesia and Surgical Specialties in Uganda.
Uganda 2025-11-07 5:05:10 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NANCY MITAKI Bonareri
ID: UNCST-2024-R003431
Biochemical Studies and Anti-diabetic mechanism of Cucurbita maxima Duchesne (Pumpkin) fruit extracts in diabetic Rats
REFNo: NS970ES

6. Determine the stability, structure’s function, and behavior of the bioactive compounds from the most active fraction of C. maxima and the target proteins,5. Predict interactions between active compounds (ligands) and diabetic target proteins such as Fibroblast growth factor 21 (FGF21), alpha-amylase and alpha-glucosidase.,4. Identify the bioactive components in the most active fraction of C. maxima fruits.,3. Determine the effects of fractions of C. maxima fruit on oxidative stress markers (Superoxide dismutase, Catalase, Glutathione peroxidase, and malondialdehyde) in diabetic rats.,2. Evaluate the effects of fractions of C. maxima fruit on liver biomarkers (Aspartate transaminase, Alanine transaminase, Alkaline phosphatase) and kidney biomarkers (Urea and Creatinine) , and histology of the liver and kidneys in diabetic rats.,1. Determine the effects of fractions of C. maxima fruit on levels of blood glucose, insulin, and activities of serum amylase and histology of pancreatic cells in diabetic rats.,To investigate the biochemical effects and antidiabetic mechanism of Cucurbita maxima Duchesne fruit extracts in diabetic rats.,
Kenya 2025-11-07 5:02:42 2028-11-07 Natural Sciences Non-Clinical Trial Degree Award
Beatrice Arwenyo
ID: UNCST-2025-R018319
Nutrient enriched biochar Fertilizer innovation from agricultural feedstock for climate smart farming. VERSION 2.0
REFNo: NS1046ES

The overall objective of the research is to produce Nutrient enriched biochar fertilizer from agricultural waste as an alternative to synthetic fertilizer. Specifically, the study intends to: i) Characterize agricultural waste for their potential use as feedstock ii) Develop Nutrient enriched biochar Fertilizer from selected agricultural waste iii) Validate the efficacy of the Nutrient enriched biochar fertilizer in pilot plots
Uganda 2025-11-07 5:01:35 2028-11-07 Natural Sciences Non-Clinical Trial Non-degree Award
Gertrude Nakigozi
ID: UNCST-2025-R022719
Pregnancy to Protection: Enhancing Vaccine Confidence for Lifelong Family Health
REFNo: HS6734ES

1. Identify factors that influence vaccine confidence among pregnant women and mothers to enhance immunization uptake at the family level, creating a positive ripple effect across the lifespan. 2. Identify opportunities for and barriers to expanding maternal vaccination coverage through evidence-based community focused approaches. For objective two we will utilize qualitative methods to understand key stakeholder level perspectives on overcoming barriers related to the 3c’s and the acceptability, feasibility, and appropriateness (implementation outcomes, operationalized as defined by proctor et al. (60)) of mass education and vaccination campaigns that reach pregnant women outside of ANC facilities to expand vaccine access and catalyze uptake within the family unit. We will also explore how other routine immunization delivery across the lifespan can be similarly optimized. Key informant participants will be identified through existing relationships with the MOH (in the case of policy level stakeholders) and community leaders (in the case of traditional birth attendants and village health team members).
Uganda 2025-11-07 5:00:01 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muzaale tonny
ID: UNCST-2023-R005970
Linking Educational Resources to Competence-Based Curriculum Implementation in Uganda’s Lower Secondary Education: The Role of Instructional Adaptability.
REFNo: SS4467ES

iii. To establish the extent to which instructional expertise in secondary schools mediates the relationship between infrastructural resources availability and competence-based curriculum implementation in lower secondary schools in Uganda ,ii. To establish the extent to which school change educational receptivity mediates the relationship between human resources quality, availability, and competence-based curriculum implementation in lower secondary schools in Uganda ,i. What is the relationship between educational resources and competence-based curriculum implementation in lower secondary schools in Uganda?,
Uganda 2025-11-07 4:57:22 2028-11-07 Social Science and Humanities Degree Award
Claire Biribawa
ID: UNCST-2023-R008347
Advancing the QUALity and EFFectiveness of alcohol and drug treatment services in Uganda (AQUALEFF - Study) through measurement of Patient reported outcomes
REFNo: HS6699ES

To assess the implementation of routine patient-reported outcome measurement and evaluate patient reported outcomes and experiences among individuals receiving treatment services for substance use disorders in Uganda
Uganda 2025-11-07 4:50:35 2028-11-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
The potential of egg powder supplementation, combined with Behaviour Change Communication, to enhance nutrition outcomes during complementary feeding in stunting-endemic areas of Kamwenge District
REFNo: HS6296ES

To develop a Theory of Change for the egg powder initiative, outlining the pathways through which the intervention is expected to improve nutrition outcomes for children 6-17 months in stunting-endemic areas in Kamwenge district.,To project trends in nutrition outcomes with prolonged egg powder supplementation among children 6-17 months in stunting-endemic areas in Kamwenge district.,Determine the change in caregiver nutrition knowledge, attitudes, and practices related to feeding of children 6-17 months receiving egg powder supplementation and social behaviour change communication in stunting-endemic areas in Kamwenge district.,Assess the change in nutrition outcomes of children 6-17 months receiving egg powder supplementation and social behaviour change communication in stunting-endemic areas in Kamwenge district,To assess the potential of egg powder supplementation combined with social behaviour change communication to improve nutrition outcomes during complementary feeding in stunting-endemic areas in Kamwenge district. ,
Uganda 2025-11-07 4:48:44 2028-11-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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