Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joseph  Matovu KB
ID: UNCST-2020-R014654
Enhancing communication on relationship preservation, safer conception, and pre-exposure prophylaxis (PrEP) to promote HIV testing
REFNo: HS3025ES

Conduct a pilot trial of “PrEPing Healthy Families” with intervention sites implementing the novel communication,Conduct formative research to expand a communication strategy focused on relationship preservation and safer conception into a multi-component intervention with broader reach,To leverage the growing availability of PrEP to determine if and how a communication strategy focused on relationship preservation and safer conception can increase testing and entry into treatment (ART) or prevention (PrEP) among couples in Uganda,
Uganda 2023-08-25 8:26:15 2026-08-25 Medical and Health Sciences Clinical Trial Non-degree Award
Christine  Muhumuza
ID: UNCST-2023-R008646
Uptake, cost-effectiveness, and experiences with HIV testing services among adolescent girls and young women in Greater Rakai, Central, Uganda
REFNo: HS2980ES

i.To assess trends of HTS uptake among adolescent girls and young women (15-24) before and after the targeted testing policy using the Rakai community cohort data from 2013 to 2022.
ii.To identify the factors associated with HTS uptake among adolescent girls and young women in Rakai using the Rakai community cohort data from 2013 to 2022.
iii. To explore experiences and preferences of adolescent girls and young women regarding HTS uptake in greater Rakai
iv. To explore the perceptions of key stakeholders regarding HTS in greater Rakai.
v. To determine the cost-effectiveness of HTS strategies in identifying HIV-positive adolescent girls and young women in greater Rakai.

Uganda 2023-08-25 8:23:39 2026-08-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
The effect of previous active tuberculosis on cardiometabolic profiles of people with HIV at an urban HIV clinic in Uganda
REFNo: HS2991ES

1. To determine the association between previous active TB and each of hypertension, dyslipidemia, elevated FBG, central obesity, and high BMI among PLHIV in Uganda, 2. To compare the frequency of each of hypertension, dyslipidemia, elevated FBG, central obesity, and high BMI among PLHIV with and without previous active TB in Uganda.,
Uganda 2023-08-25 8:21:00 2026-08-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Ajal
ID: UNCST-2023-R008516
Network for building resilience and sustainability among smallholder vegetable farmers in East Africa
REFNo: A329ES

Development of capacity for indigenous vegetables research.,Development of IPM packages for sustainability of small-holder vegetable farmers.,Identification of causal agents for key biotic constraints in African indigenous vegetables.,The main research objective is to generate eco-friendly solutions to pest and disease constraints for sustainable production of indigenous vegetables in East Africa,
Uganda 2023-08-25 8:19:01 2026-08-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
SickleInAfrica Protocol for Clinical and Implementation Research in Newborn Screening for Sickle Cell Disease Using Dried Blood Spots for Point of Care Tests.
REFNo: HS2951ES

1. To evaluate the performance characteristics of DBS POCT against IEF/HPLC.
1b. To evaluate the cost of DBS POCT against IEF/HPLC.
2. To determine the knowledge of the availability of POCTs and acceptability of the use of DBS POCT to health-care workers and parents versus standard POCT for screening in Lira Regional Referral Hospital.
3. To determine the cost of DBS POCT for NBS and confirmatory testing using POCT versus conventional NBS and confirmatory testing with IEF/HPLC: i. Apply DBS POCT in NBS versus Early Infant Diagnosis and compare the number of babies identified in each platform who enroll in comprehensive care.
ii. Train study SPARCO Lira Regional Referral Hospital health care workers on the use of DBS for POCT in newborn screening and follow up of babies identified in the programme using standardised guidelines.
iii. Screen 1000 babies in Ghana, Tanzania, Mali, Lira Regional Hospital, Uganda, Zambia and Zimbabwe while -Nigeria which has 25 subsites will screen 2,500 babies using DBS POCT and enter the identified babies into REDCap using SPARCO CRF.
` iv. Assess the implementation outcomes using CFIR
a. Assess the adoption of DBS for NBS using the three technologies POCT, IEF, HPLC among providers (i.e. midwives, physicians, nurses, councillors) in Lira Regional Referral Hospital.
b. Evaluate the appropriateness of the 3 technologies implemented at Lira Regional Referral Hospital across implementing sites and assess the barriers and facilitators guided by CFIR, inner and outer settings.
c. Assess the technology and implementation costs and sustainability of the three technologies in the various healthcare centres among the six countries.



Uganda 2023-08-25 8:13:57 2026-08-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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