Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Romeo Gichohi wahome
ID:
EFFECTIVENESS OF IMPROVISED CARDBOARD SPLINTS AS AN ALTERNATIVE TO PLASTER OF PARIS IN THE EMERGENCY TREATMENT OF LOWER LIMB FRACTURES
REFNo: HS1357ES

General Objective
1. To determine whether improvised cardboard
splints are a viable effective
alternative to plaster of Paris splints
for lower limb fractures in Mbarara
Regional and Referral
Hospital.
Specific Objectives
1. To compare the clinical effectiveness of immobilization between improvised cardboard
and plaster of Paris splint in lower limb fractures.
2. To compare the time and resource costs between improvised cardboard and plaster of
Paris in splinting of lower limb fractures.
Kenya 2021-06-11 2024-06-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Accelerating Anti-Tick Vaccine Production Using Computational Approaches and Validation with An In-Vivo Model
REFNo: NS165ES

The specific objectives of this study will be to;
i.Create an open access queryable database of candidate anti-tick vaccine protein from I. scapularis proteome
ii.Identify single and chimeric antigenic anti-tick peptides basing on tick-specific amino acid sequences
iii.Evaluate the immunogenicity of five of the most promising antigenic single and chimeric anti-tick peptides in a laboratory animal [three months New Zealand rabbits] model
Uganda 2021-06-10 2024-06-10 Natural Sciences Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
Smart discharges to improve post-discharge health outcomes in children below 6 months old
REFNo: SS855ES

To determine the effectiveness of a Smart Discharge program on post-discharge health seeking behavior and mortality among children under 6 months of age admitted with a proven or suspected infection.
Uganda 2021-06-08 2024-06-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
A multi-Centre, randomised, placebo controlled, double-blind, parallel group study to evaluate the safety, tolerability and immunogenicity of two doses of Group B Streptococcus vaccine (GBS-NN/NN2) in women who are pregnant and living with HIV and women who are pregnant and do not have HIV
REFNo: HS1390ES

Objectives
Primary Objectives:
Safety:
To evaluate the safety and tolerability of the GBS-NN/NN2 vaccine in women living with HIV and women without HIV and their newborn babies from vaccination up to delivery/birth.
Immunological:
To compare the transfer rate of vaccine- specific immunoglobulin G (IgG) antibody concentrations from the mother to the baby at birth in women living with HIV with the transfer rate in women without HIV. This endpoint will be used to determine the sample size calculation.
Secondary Objectives
Safety: The safety and tolerability of the GBS-NN/NN2 vaccine in the mother and baby over the first 6 months post-partum, as assessed at 6 months of age.
Immunological: The secondary immunological objectives are:
• To compare IgG antibody responses, specific to the GBS-NN/NN2 vaccine, induced by the first and second vaccine doses over time in pregnant women living with HIV and pregnant women without HIV.
• To evaluate the concentration of IgG antibodies specific for the GBS-NN/NN2 vaccine up to 6 months post-delivery in the mother and baby in women with and without HIV.
• To determine the concentrations of vaccine specific IgG to GBS-NN/NN2 in cord blood at delivery in babies born to women with and without HIV.
Exploratory Objectives
• To compare between groups the isotype composition of the vaccine specific antibodies; in particular IgG and IgA as well as their subclasses, i.e. IgG1-4, IgA1 and IgA2 in maternal and cord blood.
• To compare between groups the vaccine specific IgG antibodies to Rib, Alp1, Alp2 and AlpC, GBS-NN and GBS-NN2 in maternal and cord blood.
• To compare between groups the functional activity of vaccine specific antibodies from cord blood in an opsonophagocytic killing assay (OPkA) and other in vitro assays in selected samples.

Uganda 2021-06-08 2024-06-08 Medical and Health Sciences Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
Using Recency Assays to estimate incident HIV infections among Adolescent Girls and Young Women in Hoima and Mityana/Mubende Districts, Uganda Version 2.0 dated 14 April 2021: Gilead Protocol Number :CO-US-985-6117(eStimating hIv incidEnce amoNg Agyw (SIENA) Study)
REFNo: HS1439ES

Primary Objective
i) To estimate the proportion of incident recent HIV infections among AGYWs aged 16-25 years in Hoima and Mityana/ Mubende districts, Uganda.
Secondary Objective
ii) To compare HIV incidence estimated using the Asanté™ HIV-1 Rapid Recency POC kit with that obtained using the Sedia™ HIV-1 LAg-Avidity EIA and the Abbott ARCHITECT HIV Ag/Ab Combo assays.
Uganda 2021-06-08 2024-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sifiso Lukhele Mbhekeni
ID:
GENOMIC EVIDENCE OF THE ROLE OF COMMUNICATION SIGNALS IN MEDIATING REPRODUCTIVE ISOLATION AT CONTACT ZONES
REFNo: NS117ES

1. Identify the threshold of variation in communication signals above which species boundaries are maintained.
2. Determine the importance of divergence time and time since secondary contact on levels of interbreeding.
South Africa 2021-06-04 2024-06-04 Natural Sciences Non-Clinical Trial Degree Award
Irene Ayakaka
ID:
Feasibility of integrating Leprosy systematic contact follow up and Post Exposure Prophylaxis (PEP) into the Routine Leprosy Control Program in Uganda: A case study of Arua and Koboko districts
REFNo: HS1046ES

Objectives
The overall goal of the study will be to contribute to the elimination of leprosy in Uganda and to describe how best to carry out PEP with Single Dose Rifampicin (SDR) in Uganda.

Specific objectives
1. To assess the feasibility of leprosy post exposure prophylaxis in Arua and Koboko; two high burden districts in Uganda
2. To administer single dose rifampicin to eligible contacts of leprosy patients at their homes
3. To assess the factors associated with successful contact investigation for Leprosy in Arua and Koboko districts
4. To describe opportunities and synergies that can be leveraged in the districts to integrate contact investigation with other on-going community-based activities

Secondary Objectives
1. To perform leprosy data verification in Arua and Koboko districts in Uganda.
2. To assess acceptability of leprosy-contact investigation in households and in the community in Arua and Koboko districts.
3. To document the contribution of contact tracing to early leprosy diagnosis and prevention of grade2 disabilities

Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-degree Award
Danielle Barrington-Francis Jennifer
ID:
Children and their caregivers’ experiences with incontinence
REFNo: SS806ES

3. Prepare and disseminate results, recommendations and methodologies that can be used in developing more holistic, effective and inclusive humanitarian programming.,2. Collect data on attitudes towards and experiences of incontinence from children (aged five to 11), their caregivers and enabling actors through interviews, focus groups and collaborative story book methodology in Adjumani District; and,1. Develop and assess a collaborative story book methodology to engage children (aged five to 11) in humanitarian contexts in discussions of sensitive topics;,
Australia 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ceriano Mbiika
ID:
Systems Approach to ICT/Telecom Network Energy Management for Sustainability in Sub-Saharan Africa.
REFNo: SIR56ES

• To analyze the strategic, policy and regulatory frameworks employed by other countries and borrow ideas to address energy management challenges for Telecom networks in SSA. • To investigate the weaknesses in the current telecom network energy management approaches across SSA and explore complex emergent properties. • To investigate the effects and influences of economic-socio-ecological factors on the management of telecom power across Sub-Saharan Africa. • To investigate and analyze a suitable methodology and technique from the field of systems thinking that can be applied for problem structuring of current telecom network energy management across SSA. • To formulate a novel framework for guiding the management of sustainable/efficient energy solutions in ICT/Telecom networks across SSA • To use the proposed framework to contribute innovative solutions and suggestions to the energy complex problems in order to achieve holistic benefits to all the energy system’s stakeholders.
Uganda 2021-06-04 2024-06-04 Engineering and Technology Non-Clinical Trial Degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination in Uganda
REFNo: SS822ES

This protocol is solely for text and voice phone message and intervention development for a subsequent feasibility trial to improve adherence to HPV vaccination schedules in Kampala City., 2: Develop and pre-test HPV vaccine reminders with the target population, 1: Identify desired HPV vaccine text message reminder content (and parallel automated phone reminders) using key informant interviews ,
Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINTERS MUTTAMBA
ID:
A HEALTH SYSTEMS ANALYSIS AND MODELLING OF METHODS TO MAXIMIZE UPTAKE AND UTILIZATION OF ADVANCED DIAGNOSTICS IN LOW- AND MIDDLE-INCOME COUNTRIES – THE CASE OF COVID-19
REFNo: HS1337ES

1.To quantify the degree of uptake & utilization of COVID-19 diagnostic tests in Uganda, Rwanda, Kenya and UK
2.Map the pathways of uptake and ramping up COVID-19 testing in the study countries.
3.To characterise micro level and macro level factors affecting uptake and utilisation of COVID-19 diagnostic tests in Uganda, Kenya, Rwanda and UK
4.Modelling data obtained in 1) and 2) to identify best models for maximizing uptake of advanced diagnostic tests in health emergencies.
Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-degree Award
Ivaibi Charles
ID:
SELECTED CORRELATES OF WORK ENVIRONMENT AND HEALTH SERVICES DELIVERY IN HEALTH CENTRES IN BUSOGA REGION,EASTERN UGANDA
REFNo: SS798ES

(a) To establish the relationship between Support Supervision and Health Services Delivery at Health Centers in Busoga region.
(b) To study the relationship between Physical Work Environment and Health Services Delivery at Health Centers in Busoga region.
(c) To get in-depth information about the relationship between Information Management and Health Services Delivery at Health Centers in Busoga region.
(d) To design a model that will guide effective Health Services Delivery at Health Centers in Busoga region.
Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Namuga
ID:
INVESTIGATING THE POTENTIAL OF BIOACTIVE GAUZE DRESSING IMPREGNATED WITH HERB-LOADED NANOPARTICLES IN FACILITATING WOUND HEALING
REFNo: HS1393ES

The main aim of this work is to functionalise the gauze dressing using herb loaded nanoparticles to enable faster wound healing in excision wound models established in rats.

Specific objectives
1) To determine the antibacterial activity of Bidens pilosa L., Hoslundia opposita Vahl and Ageratum conyzoides L., plant extracts.
2) To determine the effect of the most efficacious antibacterial herbal extract on wound healing rate using excision wound models in rats.
3) To determine the effect of nano encapsulation of the herbal extract using biopolymers, on its antibacterial activity and wound healing rate.
4) To evaluate the effect of incorporating herb loaded nanoparticles into the gauze dressing on its antibacterial activity and wound healing rate.
5) To assess the effect of the herb loaded nanoparticles on the performance characteristic of the gauze dressing.

Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Patrick  Ogwok
ID:
Validation of the food literacy questionnaire among the adult population (18 to 69 years) living in urban Uganda
REFNo: HS1415ES

To evaluate the concurrent validity, assessing capacity of the food literacy questionnaire to distinguish between subgroups with a higher or lower food literacy.,To evaluate criterion validity by exploring associations of the food literacy questionnaire with fruit and vegetable consumption and healthy eating self-efficacy,To evaluate the reliability of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda,To evaluate the construct validity of a food literacy questionnaire against Prime Diet Quality Score within the adult population (18 to 69 years) living in urban Uganda.,To evaluate the face validity of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda ,To evaluate the content validity of a food literacy questionnaire (18 to 69 years) living in urban Uganda,To validate the food literacy questionnaire with respect to healthy eating within the adult population (18 to 69 years) living in urban Uganda. ,
Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
OTIM   ANYONI GODFREY
ID:
EFFECT OF TILLAGE AND SOIL COVER ON WEEDS IN SMALL HOLDER CONSERVATION AGRICULTURAL SYSTEMS
REFNo: A128ES

1- To compare three seed bank estimation techniques for determining weed seed density and species composition under different tillage practices and soil cover
2- To determine the effect of tillage practice on weed density, diversity and crop performance under CA systems
3- To assess the influence of crop residue and cover crop on weed density, diversity and crop performance under CA systems
4- To determine the effect of the intercrops on overall crop performance under CA systems


Uganda 2021-06-01 2024-06-01 Agricultural Sciences Non-Clinical Trial Degree Award
Pauline Harding
ID:
Ritual, Identity and Ideology: Constructing the Past in Sub-Saharan Africa
REFNo: SS258ES

I am investigating how the past is manipulated to support present-day ideological agendas in sub-Saharan Africa, in order to understand the ways in which new histories are constructed to reinforce and legitimate group identities and ideologies. I will assess where such constructions ¬– for example at museums, educational institutions and heritage sites, and through intangible heritage displays and local neo-traditional (ritual) activities – reveal disparities between academic renderings of the past and histories that are generated by, and for the use of, the public. I will also assess the active role of heritage sites and intangible heritage practices – and therefore the social responsibilities of archaeologists and heritage workers – in shaping societies in sub-Saharan Africa today; and help archaeologists to recognise and appreciate that the past is evolving in the present, independent of their own work and an aging base of historical knowledge. Uganda is a particularly interesting example of this because, while recent historical work there has been limited, an explosion of newly constructed local histories serves increasingly to distort the historical record. The research will generate important information which will be useful to sites including the Uganda Museum as a source of data and debate as they plan their future development.
UK 2021-05-28 2024-05-28 Social Science and Humanities Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
Describing the effect of the covid-19 pandemic on tuberculosis care in Uganda
REFNo: SS820ES

To determine the association between access to TB inpatient care services, respiratory symptoms and QoL of patients diagnosed with TB during different phases of the COVID19pandemic,To assess barriers and enablers to accessing TB diagnostic and treatment services during the different phases of the pandemic.,To assess sociodemographic differences between patients accessing TB care services during different phases of the COVID 19 pandemic ,To describe characteristics of patients accessing TB care during different phases theCOVID19 pandemic and to identify enablers and barriers to care seeking during the different phases of the pandemic.,
Uganda 2021-05-28 2024-05-28 Social Science and Humanities Non-degree Award
Hamson Kanyesigye
ID:
ASSESSMENT OF INTRAPARTUM REFERRALS AND USE OF MOBILE PHONE TECHNOLOGY TO IMPROVE MATERNAL-FETAL OUTCOMES IN SOUTH WESTERN UGANDA
REFNo: HS543ES

General Objective
To assess Maternal Referral processes between Health centre IVs and Mbarara Regional Referral Hospital, and effect of mobile phone technology on maternal and fetal outcomes among referred patients.
Specific objectives
1. To describe patient referral processes between Health centre IV in Isingiro district and Mbarara Regional Referral Hospital.
2. To establish acceptability of phone based intervention among health workers at lower level health units

3. To establish the effect of a phone based intervention on maternal and perinatal deaths among Intrapartum referrals

4. To compare the rates of maternal near-miss conditions and other poor fetal outcomes besides death across study arms

5. To identify the causes of delay following a phone based intervention

Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
Alcohol and Social Media use among university students: Perceptions, patterns and experiences, and the feasibility of social media based interventions for alcohol prevention
REFNo: HS849ES

1. To assess prevalence, patterns and associations of alcohol and social media use among university students
2. To explore university students’ perceptions about alcohol and social media use
3. To explore experiences of university students regarding alcohol and social media use
4. To explore student perspectives on possibilities and opportunities of using social media based interventions for alcohol prevention among university students

Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Agapitus Kato Babumba
ID: UNCST-2021-R013866
Evaluation of the feasibility of SumiShield™ 50WG Insecticide use in the control of malaria vectors in COVID-19 patients’ isolation centres in Uganda
REFNo: HS1256ES

1. To determine the efficacy and residual activity of SumiShieldâ„¢ 50WG insecticide against malaria mosquitoes on plastered and painted wall surfaces in COVID-19 isolation centres in Uganda.

2. To determine the susceptibility of wild Anopheles gambiae mosquitoes to SumiShieldâ„¢ 50WG and other commonly used mosquito insecticides in the study area.
Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Irene Kahimakazi
ID:
Prevalence and factors associated with gestational diabetes mellitus among women attending antenatal care at Mbarara Regional Referral Hospital
REFNo: SS854ES

1. To determine the prevalence of gestational
diabetes mellitus among women attending antenatal
care clinic at Mbarara Regional Referral
Hospital South Western Uganda
2. To establish the factors associated with
gestational diabetes mellitus among women
attending antenatal care clinic at
Mbarara Regional Referral Hospital, south
western Uganda

Uganda 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Phocas Nyandwi -
ID:
Effect of Firm Financial Strength Factors on Income Retention of General Insurers in East Africa
REFNo: SS829ES

To determine the moderating effect of firm size on the relationship between firm financial distress factors and income retention of General insurers in East Africa,To establish the effect of earnings volatility on income retention of General insurers in East Africa,To assess how liquidity affects income retention of General insurers in East Africa,To investigate the effect of leverage on income retention of General insurers in East Africa,To determine the effect of capital adequacy on income retention of General insurers in East Africa,The general objective of the study is to investigate the effect of firm financial strength factors on income retention of General insurers in East Africa.,
Burundi 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Arunga
ID:
Management of microbial keratitis by private pharmacies in Uganda: a study of knowledge, attitude and practice
REFNo: HS1082ES

1. To determine the Knowledge of private pharmacy workers in Uganda in the management of Microbial Keratitis.
2. To describe the current practice for the management of Microbial Keratitis among private pharmacies in Uganda .
3. To explore ways to engage local pharmacy attendants to improve referral of patients with suspected Microbial Keratitis.

Uganda 2021-05-25 2024-05-25 Medical and Health Sciences Non-degree Award
Dao Ho
ID:
Palliative Care Needs Assessment in the Emergency Department in Kiruddu Hospital
REFNo: SS796ES

Objective 1: Describe the prevalence of palliative care needs among emergency care patients. In order to assess this objective, we will conduct a palliative care needs survey with patients and health care workers in the Kiruddu Hospital Emergency Department. Objective 2: Explore and illustrate identifiable strengths as well as barriers to delivery of palliative care in the emergency department. In order to assess this objective, we will conduct one-on-one interviews with health care workers in the Emergency Department to further explore this topic.
USA 2021-05-24 2024-05-24 Social Science and Humanities Non-Clinical Trial Degree Award
Gilbert Sendugwa Sendugwa
ID:
Towards Gender Balance: Understanding the Barriers and Solutions to Include Women-Led Businesses in East Africa
REFNo: SS712ES

This research will document policies and practices that exclude and include women-led businesses in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda. Specifically, it aims to: - Understand the participation of and challenges facing women-led businesses and sole proprietorships in the five countries and regionally. - Identify measures being implemented or tested to improve fairness and inclusion of women in public procurement in the selected countries. - Assess the effectiveness of the measures put in place by specific governments to improve fairness and inclusion. - Recommend actionable changes to improve the current situation, based on the findings of the research and international best practice.
Uganda 2021-05-21 2024-05-21 Social Science and Humanities Non-degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
GROUP B STREPTOCOCCUS GENITAL COLONIZATION PATTERNS AMONG NON- PREGNANT WOMEN OF REPRODUCTIVE AGE AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: HS728ES

General objective
To determine how colonization with GBS changes over time among non-pregnant women of reproductive age and how the changes correlate with the host immunity
Specific objectives
1. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were uncolonized at baseline
2. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were colonized at baseline

3. To determine whether the concentration of GBS IgG in serum correlates with the concentration of GBS IgG at the vaginal mucosa
4. To determine whether we can predict colonization from GBS IgG concentration in blood
5. To determine whether we can predict colonization from GBS IgG concentration in the vaginal mucosa

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Kinyi Wambui
ID:
“Effect of varying ratios of dietary macronutrients on immune system function of Swiss albino mice”
REFNo: NS159ES

i. To assess the effects of varying macronutrient ratios on the nutrition status of Swiss albino mice
ii. To evaluate the effects of varying macronutrients ratios on leucocyte count, neutrophil adhesion and cytokine production of Swiss albino mice
iii. To determine the effects varying ratios of macronutrients on the production of pro-inflammatory (TNF-α, IFN-γ, IL-6) and anti-inflammatory (IL-10) cytokines in Swiss Albino mice challenged with lipopolysaccharide
iv. To evaluate the effects of varying macronutrients ratios on delayed -type hypersensitivity and antibody titers of Swiss albino mice challenged with cow red blood cells (CRBC)

Kenya 2021-05-20 2024-05-20 Natural Sciences Degree Award
Enock Matovu
ID:
Development and Evaluation of Recombinant SARS-CoV-2 Spike and Membrane Protein-Based Sub-Unit Vaccines
REFNo: NS146ES

(i) To express recombinant subunits of the RBD region of the spike protein and the M protein
(ii) To characterize the humoral and cell mediated immune response generated by the RBD region and the M protein in mouse models
(iii) To determine the safety of the vaccine candidates in mouse models
(iv) To determine the efficacy of the potential candidate vaccine in mice

Uganda 2021-05-20 2024-05-20 Natural Sciences Non-degree Award
Lena Mpalampa
ID:
FACTORS ASSOCIATED WITH PROVISION OF PHYSICAL ACTIVITY IN PRIMARY SCHOOLS IN MAKINDYE DIVISION IN KAMPALA
REFNo: SS768ES

5. To establish the school related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,4. To establish the class related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,3. To ascertain the teacher related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,2. To describe the various types of physical activity offered in primary schools in Kampala during the school term,1. To determine the proportion of schools offering sufficient time for PA among primary schools in Kampala during the school term,To analyse the factors associated with insufficient physical activity offered in primary schools in Makindye Division in Kampala during the school term.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Degree Award
Katelin Wilton
ID:
Supporting Families through Community Health Workers during COVID: A feasibility and acceptability study
REFNo: SS752ES

Main objective/ purpose
The main objective of this study is to better understand coping strategies of frontline health workers, feasibility and acceptability indicators of messaging success.
Specific Objectives
The specific objectives of this study are to:
• Understand frontline health workers perspective on their stress and psychosocial wellbeing
• Understand the feasibility and acceptability of behaviorally-informed SEL and MHPSS messaging targeted at adult and child clients delivered through frontline health workers
• Determine whether such messaging targeted at clients may also improve frontline health worker coping strategies

USA 2021-05-20 2024-05-20 Social Science and Humanities Non-degree Award
Paul Atherton
ID:
Girls’ Education Challenge Phase II: Continued Access and Learning during Covid-19 in GEC-II PEAS treatment and control schools in Uganda
REFNo: SS764ES

The final research questions for the proposed study are listed below:

a) How have PEAS sought to provide continued access to learning opportunities during school closures?
b) How are the PEAS supporting girls to return to school, and with what effects on girls’ access to learning opportunities?
c) How are PEAS identifying which girls are most at risk of not returning to school? Can a scorecard approach help projects identify those most at risk within projects in a cost-effective way?
d) How have girls’ learning levels changed during the COVID-19 period?

UK 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINNIE NAMBATYA
ID:
Evaluation of the complexity of medicine regimens and drug therapy problems among children with sickle cell anemia in Jinja Regional Referral Hospital: A prescription audit
REFNo: HS1299ES

• To determine the complexity of medication regimens prescribed to the patients with SCA.
• To determine the incidence of DTPs among medications prescribed to children with SCA.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
ALERT – ACTION LEVERAGING EVIDENCE TO REDUCE PERINATAL MORTALITY AND MORBIDITY IN SUB-SAHARAN AFRICA
REFNo: HS1324ES

To develop and evaluate a multifaceted intervention to i) strengthen the implementation of evidence-based interventions and responsive care and ii) reduce in-facility perinatal mortality and morbidity through a multidisciplinary approach in Benin, Malawi, Tanzania and Uganda.
Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
Mark Okwir
ID: UNCST-2021-R013417
Spectrum, Outcomes, and Factors Associated with the Liver disease in a Tertiary Care Hospital, Northern Uganda: a 5 Year Retrospective Study.
REFNo: HS1333ES

General Objectives
To determine the spectrum, outcome, and factors associated with liver disease in patients admitted at Lira hospital in northern Uganda over the last five years.

Specific Objectives:
1. To describe the spectrum of liver disease among patients admitted to Medical wards in Lira Regional Referral Hospital over the last five years.
2. To determine the factors associated with liver disease among patients admitted with liver disease at Lira Hospital in the last five years.
3. Determine the admission outcomes (mortality and survival) of liver diseases among patients admitted at Lira Reginal Referral Hospital in the last five years.
4. To determine the factors associated with the admission outcomes (mortality and survival) of patients admitted with liver disease at LRRH in the last five years.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
SHAMIM NAMUKASA
ID:
Prevalence of Sickle Cell Trait and Needs Assessment for Up-Take of Sickle Cell Screening Among Secondary School Students in Kampala City
REFNo: SS818ES

To explore the stakeholders' perceptions regarding the uptake of sickle cell screening among secondary school students in Kampala City,To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,To determine the prevalence of sickle cell trait among secondary school students in Kampala City,Determine the prevalence of sickle cell trait among secondary school students and identify student-related and stakeholders' factors influencing up-take of sickle trait screening,3. To Explore the stakeholders' perspectives regarding the uptake of sickle cell screening services among secondary school students in Central Uganda.,2. To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,1. To determine the proportion of sickle cell among secondary school students in Central Uganda.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Lubega Biyinzika
ID: UNCST-2020-R014149
Perceptions and adherence to preventive measures for Coronavirus Disease 2019 among rural community households in Wakiso district, Uganda.
REFNo: SS819ES

3. To explore community barriers and facilitators of adherence to COVID-19 preventive measures among rural community households.,2. To assess adherence to COVID-19 preventive measures as issued by the Government of Uganda among rural community households.,1. To assess perceptions towards COVID-19 preventive measures among rural community households. ,To assess community perceptions and adherence to COVID-19 preventive measures in rural community households of Wakiso district, Uganda in order to provide essential information needed by public health officials and other stakeholders to make an informed decision on the most effective strategy for reduced community transmission.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
Prevalence of Polymorphic genes of Alzheimer disease in Nodding disease Tauopathy.
REFNo: HS726ES

To determine if polymorphisms in the eight common genes associated with Alzheimer Disease (APP, MAPT, PREN-1, PREN-2, BACE-1, BACE-2, IDE, and APOE-ε4) are present in DNA of Nodding Disease patients
Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
Selecting Single Component Adjuvants for Vaccine Formulations
REFNo: HS821ES

1. To determine if adjuvants induce maturation of dendritic cells from healthy donors, LTBI and asymptomatic VL
2. To determine if adjuvants induce antigen-independent proliferation of different lymphocyte populations from healthy donors, LTBI and asymptmatic VL.
3. To measure levels of cytokine production induced by the different adjuvants
4. To determine if adjuvants induce cytotoxicity (as measured by annexin V).

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
Neurodevelopmental, Behavioural and Physical Growth Outcomes of Children born to Mothers with Nodding Syndrome in Northern Uganda.
REFNo: HS852ES

Primary Objective
To determine the neurodevelopmental and behavioural outcomes of children born to mothers suffering from nodding syndrome compared to children of healthy mothers.

Secondary Objectives
1.To describe adverse medical conditions children of mothers of nodding syndrome have experienced from birth
2.To determine physical growth outcomes among children born to NS patients.
3.To determine the effect of seizure burden (frequency and duration) during pregnancy on child neurodevelopmental outcomes.
4.To determine the effect of caregiver emotional wellbeing on child neurodevelopmental outcomes.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Wilson  Tumuhimbise
ID:
A mobile health framework for public private mix in Tuberculosis prevention and care in Uganda
REFNo: HS963ES

1). To explore the barriers and motivators to private hospital engagement in TB care among private healthcare workers with particular focus on understanding the current Public Private Mix frameworks utilized.
2). To develop a mobile phone based framework for enhancing the tracking of TB patients referred from private to public hospitals and assess its initial acceptability and feasibility
3). To assess the preliminary impact of the mobile phone based framework on TB patients’ adherence to referrals for TB diagnosis and treatment in public hospitals.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
Catalyzing Change in Education through a Transformative Learning Collaborative: Scaling-Up of a Social Emotional Learning Curriculum in Uganda A Phase III Randomized Control Trial
REFNo: HS1189ES

Specific Objectives
1. To identify effective strategies to integrate the PD-SEL curriculum into Nakaseke Core Primary Teachers College by applying a learning collaborative approach
2. To carry out additional Professional development adaption of a behavioral management program (PARENT-CORPS) enhancement by integrating teacher/adult SEL training and gender equity. (the PARENT-CORPS program is being adapted at Kibuli CPTC and Bulera CPTC in Hoima but without the SEL component)
3. To evaluate the effectiveness of PD-Enhanced on teachers’ and students’ SEL/SEC when implemented using a task-shifting model with PTC tutors and incorporating a gender-sensitive approach

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Josephine  Ndagire
ID:
Assessment of Justice Delivery for Children Victims of Defilement
REFNo: SS744ES

The main objective of the research is to assess the response of the justice sector in Uganda to the issue of defilement throughout the justice chain in the last decade and the role that the legal framework particularly the law on defilement (as amended in 2007) has played in facilitating or impeding the actions by the sector and ultimately make recommendations on policy and institutional reforms to address the high defilement rates in the face of strong legal guarantees.
Uganda 2021-05-18 2024-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Steven Ndugwa Kabwama
ID:
Risk Factors for Non-Communicable Diseases among Adults in a District with a High Prevalence of Schistosomiasis
REFNo: HS1289ES

1. To estimate the prevalence of risk factors for NCDs such as alcohol intake, tobacco use, fruit and vegetable intake, obesity and physical activity among adults in Buyende District.
2. To determine the prevalence of schistosomiasis infection among adults in Buyende District.
3. To assess the factors associated with the risk factors for non-communicable diseases (alcohol use, tobacco use, fruit and vegetable intake, obesity) among persons presenting with or without schistosomiasis infection.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Johnbosco Turyasingura
ID:
Community participation and sustainability of donar funded potato projects in Kabale district
REFNo: SS758ES

i. To examine effect of project design and implementation of donor funded potato projects in Kabale District.
ii. To determine the effect of project resourcing on sustainability of donor funded potato projects in Kabale District.
iii. To determine the effect of project monitoring and evaluation on the implementation of donor funded potato projects in Kabale District

Uganda 2021-05-18 2024-05-18 Social Science and Humanities Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
Novel and Optimized Diagnostics in Pediatric Tuberculosis in Kampala, Uganda(NOD)
REFNo: HS1341ES

The study has the following objectives:
Objective 1: Evaluate and develop novel assays that diagnose TB by detecting Mycobacterium tuberculosis (MTB) bacterial products in non-sputum body fluids. Objective 2: Evaluate and develop novel assays that diagnose TB by detecting host biomarkers in non-sputum body fluids.
Objective 3: Identify combinations of assays that applied together could be used to diagnose TB among children with unconfirmed.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
Impact and process Evaluation of the Health-Professional Education Partnership Initiative – Transforming Ugandan Institutions Training Against HIV/AIDS
REFNo: HS1351ES

1. To evaluate the acceptability, appropriateness, feasibility, and implementation process of the HIV curriculum
2. To evaluate the acceptability, appropriateness, feasibility, and implementation process of building capacity of primary health care (PHC) providers to provide comprehensive HIV services and strengthen bidirectional linkages between health facilities and communities
3. To evaluate the acceptability, appropriateness, feasibility, and implementation process of the micro-research program

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
A phase I study to determine the safety and immunogenicity of the candidate Rift Valley Fever Virus (RVFV) vaccine ChAdOx1 RVF among healthy adult volunteers in Uganda.
REFNo: HS793ES

The primary objective of this study is to assess the safety profile of the candidate vaccine ChAdOx1 RVF in healthy adult volunteers in Uganda. This will be assessed through comparing the frequency of solicited, unsolicited and serious adverse events and changes from the baseline of laboratory safety measures between participants who will receive the active vaccine and those who will receive the placebo.
The Secondary objective is to assess the immunogenicity of the candidate vaccine ChAdOx1 RVF in healthy adult volunteers in Uganda. This will be assessed through quantification of antibodies to the GnGc proteins using ELISA, RVFV neutralising antibody titres and Ex vivo ELISpot and flow cytometry responses to GnGc.
Uganda 2021-05-17 2024-05-17 Medical and Health Sciences Non-degree Award
Allen Kabagenyi
ID:
Impoverishing and Catastrophic health expenditure on cancer care among persons affected by cancer in Uganda
REFNo: SS851ES

1. To determine the out of pocket expenditure associated with cancer care for persons affected by cancer, by type and stage;
2. To determine the proportion of cancer patients and or their families that experience catastrophic or impoverishing expenditure due to cancer related expenses by cancer type and stage;
3.To characterize the socio-economic interruptions experienced by persons affected by cancer in Uganda.
4.To examine the sociodemographic characteristics associated with cancer care burden in Uganda
5.To assess patients and care givers perceptions and attitudes of cancer care expenditures and health care in Uganda


Uganda 2021-05-17 2024-05-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
Integration of buprenorphine into a multi-component harm reduction program for people who inject drugs in Kampala, Uganda
REFNo: HS1229ES

To develop a combination HIV prevention intervention for PWID in Kampala Uganda, using the Consolidated Framework for Intervention Research. The combination intervention includes social network HIV/HCV testing, linkage to care for PWID and PrEP for HIV negative PWID. All participants will be offered safe injection equipment, condoms and HIV risk reduction education, and naloxone, buprenorphine, and CBT4CBT for heroin users.
2. To refine the intervention iteratively through implementation cycles using the CFIR framework to identify barriers and find solutions to implementation and scale-up.
3. To assess feasibility, acceptability and initial promise of the intervention with a 6-month pilot test.

USA 2021-05-10 2024-05-10 Medical and Health Sciences Non-degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
Engaging Young People in the Development of Digital Mental Health Innovation in Africa
REFNo: SS795ES

To build a network of experts and stakeholders to develop a framework for responsible and relevant digital mental health interventions for young people in African countries
Uganda 2021-05-10 2024-05-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
Management of Lower Respiratory Tract Infections in Sub-Saharan Africa, a Pragmatic Approach
REFNo: HS1160ES

Primary objective: To define aetiology and resistance patterns of clinically diagnosed CAP among hospitalized individuals using a comprehensive microbiological approach.

Secondary objectives:
1.To determine the level of agreement between molecular and conventional laboratory testing for the diagnosis of CAP.
2.To determine clinical predictors of treatment outcomes (early treatment failure, mortality) in patients hospitalized with CAP.
3.To determine the role of the CURB-65 severity score and biomarkers (CRP and PCT) in predicting treatment outcomes (early treatment failure, mortality) of patients hospitalized with CAP in a high HIV burden setting.

Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-degree Award
Kenneth Mutesasira
ID:
Patient perspectives and reasons for interruption of TB treatment within central Uganda.
REFNo: HS1383ES

-The overall aim of the study is to understand patient reasons for treatment interruption to inform the interventions for improving TB patient retention and final treatment outcomes.
- The second objective is to explore patient's suggestions for improving their adherence throughout the course of treatment.
Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Semitala Fred
ID: UNCST-2020-R014202
An assessment of current hypertension care (HTN) practices, routines, barriers, and facilitators for people living with HIV at selected health facilities in Kampala and Wakiso Districts in Uganda. A Formative Study
REFNo: SS808ES

Objective 1: To assess for knowledge, attitudes and practices of hypertension management and control.
Objective 2: To document existing guidelines and recommended routines for HTN-HIV integration in HIV clinics.Objective 3: To assess the current practice, routines, barriers and facilitators of HTN-HIV integration in HIV clinics.
Objective 4: To explore key stakeholders’ perspectives on HTN-HIV integration in HIV clinics in Kampala and Wakiso Districts.


Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-degree Award
James Nyonyintono Mwangwa
ID: UNCST-2023-R005636
Reporting neonatal demographics, clinical characteristics and outcomes using the deidentified Kiwoko Hospital newborn care unit database
REFNo: SS813ES

Aim 1- Describe demographics, clinical characteristics and outcomes of neonates Aim 2- Describe mortality by birthweight and birth location Aim 3- Evaluate the changes to growth and length of stay after introduction of cue-based feeding in 2019 Aim 4- Evaluate the short-term clinical correlates to a diagnosis of birth asphyxia Aim 5- Determine if frequency of low birthweight admissions correlates to transmission of p. falciparum and decreased use of insecticide treated nets
Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Task Shifting Screening and Measurement of Blood Pressure and Blood Sugars by Community Health Workers for Early Detection and Referral of Hypertension and Diabetes in Rural Uganda.
REFNo: SS821ES

1. To train CHWs in detection, referral, and promotion of continuity for diabetes and
hypertension care among community members in Nakaseke district, Uganda.
2. To assess the ability of trained CHWs to detect and refer patients with diabetes and or hypertension in Nakaseke district.
3. To determine compliance to diabetes and hypertension referral care among community
members in Nakaseke district
Uganda 2021-05-07 2024-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
VACCINATION COVERAGE AND ITS DETERMINANTS AMONG CHILDREN AGED 0 TO 59 MONTHS IN KENYA / UGANDA: A HOUSEHOLD SURVEY
REFNo: HS1391ES

STUDY OBJECTIVES

Broad Objective
The main objective of the baseline and endline surveys is to determine the current status and uptake of immunization services in Living Goods’ focus areas in Kenya and Uganda.
Specific Objectives
The specific objectives of the baseline and endline surveys in Kenya and Uganda are to:
1. Determine the percentage of children (aged 0-59 months) fully vaccinated before and after implementation of the program.
2. Determine the equity or lack thereof in immunization coverage.
3. Assess knowledge, skills (CHWs only) and attitudes of CHWs and caregivers of children aged ≤59 months before and after the intervention.
4. Determine health system factors (stock outs, outreaches, micro-plans, etc.) that facilitate or deter vaccine uptake.

Uganda 2021-05-07 2024-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Namugumya
ID:
TALENT MANAGEMENT IN UNIVERSITIES IN UGANDA
REFNo: SS681ES

1. To examine the relationship between self-organisation and talent management.

2. To examine the relationship between organisational culture and talent management.
3. To examine the relationship between emotional intelligence and talent management.
4. To examine the relationship between adaptability and talent management

5. To examine the relationship
between self-organisation and Adaptability.
6. To examine the relationship between organisational culture and adaptability.
7. To examine the relationship between emotional intelligence and adaptability.
8. To examine the mediating role of adaptability on the relationship between self -organisation and talent management.

9. To examine the mediating role of adaptability on the relationship between organisational culture and talent management.

10. To examine the mediating role of adaptability on the relationship between emotional intelligence and talent management.
Uganda 2021-05-05 2024-05-05 Social Science and Humanities Degree Award
Ezekiel Mupere
ID: UNCST-2021-R011972
Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children PB-SAM.
REFNo: HS1193ES

General Objective
• To determine whether treatment with pancreatic enzymes or bile acids reduce mortality in acutely ill hospitalized children with severe malnutrition compared to placebo.

Specific Objectives
To determine:
1. Rate and type of SAEs (including readmissions to hospital)
2. Safety: rate of grade 3 or 4 toxicity events whilst receiving investigational products
3. Intestinal function: number of days with diarrhoea during admission.
4. Use of second and third-line antibiotics during admission and readmission
5. Number of days from enrolment to discharge during admission
6. Growth: (MUAC, weight-for-length, length-for-age) to day 60.

Uganda 2021-05-05 2024-05-05 Medical and Health Sciences Non-degree Award
Engineer  Bainomugisha
ID: UNCST-2023-R005928
End-to-end Artificial Intelligence (AI) and data systems for targeted surveillance and management of COVID-19 and future pandemics affecting Uganda (COAST)
REFNo: SIR61ES

1.To strengthen data systems for usable and equitable datasets for AI-driven COVID-19 responses and future pandemics

2.To model and evaluate COVID-19 interventions for targeted government responses.

Uganda 2021-05-05 2024-05-05 Engineering and Technology Non-Clinical Trial Non-degree Award
Anna Vitali
ID:
Why do firms in Low-Income Countries grow slowly? An Investigation of Demand Side Mechanisms
REFNo: SS711ES

Why do firms in low-income countries grow slowly? My research will provide new evidence on demand-side constraints, that is the challenges that firms face in building a customer base. Specifically, I will study how limited information on product quality restricts the ability of high-quality firms to attract consumers.

Accessing new customers may be especially difficult in developing countries due to high search costs and the lack of institutions that can enforce quality standards. High search costs make it hard for consumers to learn about the existence and the quality offered by different sellers in the market. At the same time, the lack of institutional capacity to enforce quality standards increases the probability of meeting extremely low-quality sellers in the market, thus reducing consumers’ willingness to try out new firms. This type of frictions significantly restricts the ability of high-quality producers to capture customers from lower-quality firm, allowing for the survival of a mass of small, unproductive businesses in the economy.

Customers’ limited ability to observe goods quality can also lead to discrimination against particular groups. For instance, recent studies have shown that individuals tend to underestimate the ability of women relative to men in male-typed domains. If the quality of goods is hard to observe and customers believe that, on average, men have higher ability than women in male-dominated sectors, female entrepreneurs may face significant discrimination from customers when entering male-dominated, high-productivity industries. This could contribute to gender-based employment segregation, one of the leading causes of gender disparity in the labour market.

The findings from my research will shed light on the mechanisms through which policies aimed at improving information on product quality may stimulate firm expansion and employment creation, as well as reduce gender-based employment segregation in low-income economies.

Italy 2021-04-29 2024-04-29 Social Science and Humanities Degree Award
Tonny Kiyimba
ID:
Dietary pattern and cardio-metabolic profiles of HIV positive Ugandans
REFNo: HS1355ES

3. Assess the association between lifestyle factors (smoking, alcohol consumption and physical activity) and metabolic health of HIV positive Ugandans,2. To assess the association between ART regimen and duration and metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of patients with HIV in Uganda,1. To assess the association between dietary intake and metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of patients with HIV in Uganda ,To assess the dietary patterns and cardio-metabolic risks of HIV positive Ugandan adults,
Uganda 2021-04-28 2024-04-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Tumwerinde Emmanuel Aturinde
ID:
Towards a Regendered Military and Women Participation in the AMISOM
REFNo: SS723ES

i. Explore the nature of gender relations in the military institution and its influence on selection, training and deployment of women in peace operations
ii. Analyse the history of women participation in peace operations with reference to the Kenya and Uganda as AMISOM Troop Contributing countries
iii. Examine the roles and experiences of women combatants in peace operations.
iv. Analyse how women participation and experiences in peace operations have contributed to change in gendered military relations in the context anti-antiterrorism Missions.

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
The gendered price of precarity. Young women navigating workplace sexual harassment.
REFNo: SS608ES

Principal aim
The principal aim of the project is to contribute to an understanding of the processes of empowerment of young females in response to (vulnerability to) WSH, in order to inform policy directions and civil society efforts aimed at empowering young workers.

Specific objectives are:
1) To contribute to a better understanding of processes of gaining voice and empowerment in response to WSH in different precarious labour settings, by highlighting variation between the formal and informal sector.
2) To contribute to empirical knowledge about WSH in sectors for which limited research exists, and from a youth perspective.
3) To raise awareness among relevant policy actors about the specific conditions that create vulnerability to WSH for young women working in selected formal and informal sectors, and help them design strategies to address this within employment interventions.
4) To contribute to policy development for addressing sexual harassment in the informal sector, in support of implementing Article 8 of ILO Convention 190.
5) To contribute to the development of an ‘everyday language’ in local vernacular in Uganda and Bangladesh, which policy actors, civil society, and young women can comfortably use to articulate WSH.

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Olivia Kituuka
ID:
INFORMED CONSENT PROCESS FOR EMERGENCY SURGERY AT PUBLIC AND PRIVATE HOSPITAL SURGICAL EMERGENCY UNITS IN THE URBAN UGANDAN SETTING
REFNo: HS1208ES

i. To explore and describe patients’ experiences and satisfaction with the informed consent process for emergency surgery, at both public and private not for profit teaching hospitals in Uganda
ii. To explore the roles, perceptions and experiences of the next of kin of patients who have undergone emergency surgery on the informed consent process at both public teaching hospital and private not for profit teaching hospitals in Uganda.
iii. To determine the factors that influence informed consent practices of emergency department staff involved in the informed consent process for emergency surgery in public and private not for profit teaching hospitals in Uganda

Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Degree Award
Jenna Grzeslo
ID:
Exploring the Feasibility of Empowerment and Livelihood for Adolescents (ELA) in an Afterschool Setting: Formative Research to Inform Programming and Policy in Uganda
REFNo: SS693ES

1. BRAC would like to explore the feasibility of school and government uptake of the programming.

2. Finally, to inform future experimental evaluations, we seek to understand the role of dosage (e.g., the number and frequency of meetings) in designing the updated ELA curriculum.
USA 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Pakoyo Kamba Fadhiru
ID:
A prospective cohort study of oral morphine self-medication by caregivers of paediatric patients at Mulago National Referral Hospital, Kampala
REFNo: HS1331ES

To determine the effect of diversion of patients’ oral morphine by caregivers on their health related quality of life and that of patients in paediatric clinics at Mulago National Referral Hospital,To determine the prevalence and compliance with necessary written internal controls for prescribing, dispensing and administration of oral morphine by paediatrics clinics at Mulago National Referral Hospital,To determine the effect of home-based oral morphine use in palliative care on drug use disorders among caregivers of paediatric patients at Mulago National Referral Hospital. This will be achieved by comparing the prevalence and incidence of self-medication with oral morphine and other controlled drugs between caregivers of paediatric patients with and without prescribed oral morphine.,To determine the factors associated with self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital,To determine the prevalence and incidence of self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital. This will be achieved through a baseline survey of prevalence followed by longitudinal evaluation of incidence of self-medication at endline.,To understand the compliance of paediatric clinics with oral morphine controls and the effect of diversion of patients’ oral morphine by caregivers on the quality of life of paediatric patients and caregivers,4. To determine the effect of diversion of patients’ oral morphine by caregivers on their health related quality of life and that of patients in paediatric clinics at Mulago National Referral Hospital.,3. To determine the prevalence and compliance with necessary written internal controls for prescribing, dispensing and administration of oral morphine by paediatrics clinics at Mulago National Referral Hospital.,2. To determine the effect of home-based oral morphine use in palliative care on drug use disorders among caregivers of paediatric patients at Mulago National Referral Hospital. This will be achieved by comparing the prevalence and incidence of self-medication with oral morphine and other controlled drugs between caregivers of paediatric patients with and without prescribed oral morphine.,1. To determine the prevalence and incidence of self-medication with oral morphine among caregivers of paediatric patients on prescribed oral morphine in paediatrics clinics at Mulago National Referral Hospital. This will be achieved through a baseline survey of prevalence followed by bimonthly longitudinal monitoring of incidence of self-medication.,
Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-degree Award
Sophie Mylan Katherine Hardman
ID:
Epidemics in Refugee Settlements: An ethnographic exploration of ‘Preparedness’ in Palabek Refugee Settlement, Northern Uganda, during times of COVID-19
REFNo: SS745ES

The objective of this study is to understand how epidemic ‘preparedness’ in refugee settlements can pay greater attention to histories, ideas and practices from refugees themselves. Through ethnographic research, including, but not restricted to, fieldwork in Palabek Refugee Settlement, northern Uganda, during times of COVID-19, the connections and disconnections between global policy, biomedical approaches, and ‘preparedness from below’ will be explored as equal objects of study.
UK 2021-04-27 2024-04-27 Social Science and Humanities Degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
PRELIMINARY INVESTIGATIONS TO SUPPORT COVID-19 VACCINE ROLL-OUT IN UGANDA [CO-ROLL]
REFNo: SS767ES

The study objectives are
1. To assess uptake of COVID-19 vaccination and associated factors among HCWs and older (>50 years) persons in Uganda
2. To describe the knowledge and attitudes towards COVID-19 vaccines among HCWs and older (>50 years) persons in Uganda
3. To describe the profile of anti-SARS-CoV-2 IgG antibodies before and after vaccination in HCWs and older (>50 years) persons in Uganda.
4. To describe cellular immune responses to SARS-CoV-2 antigens before and after vaccination in HCWs and older (>50 years) persons in Uganda.
5. To describe pre-COVID-19 immunisation innate response profiles, and relate these to the antigen specific vaccine responses in HCWs and older (>50 years) persons in Uganda
6. To determine the social and structural factors that influence uptake of COVID-19 vaccines in HCWs and older (>50 years) persons in Uganda

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Mangeni
ID:
Utility of pooled sputum samples for Tuberculosis screening in a high TB burden setting.
REFNo: HS1329ES

- The overall aim of this study is to determine sensitivity and specificity of pooled sputum samples in the diagnosis of TB in a healthcare setting in Uganda

Secondary objectives
- To determine the effect of varying bacterial loads on the sensitivity and specificity of sputum pooling
- To determine the effect of different pooling ratios on the sensitivity and specificity of sputum pooling
Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-degree Award
FREDRICK MAKUMBI
ID:
Understanding how information on abortion is shared in social networks: a mixed-methods follow up study to refine two social network-based methods for measuring abortion incidence
REFNo: SS814ES

This study aims to understand how information on pregnancy termination is shared within social networks and use this information to assess and improve the use of two social-network based methods for estimating abortion incidence.

Specific objectives
(1) Improve the robustness and accuracy of the estimate of abortion incidence in Uganda
(2) Assess how diffusely information about pregnancy termination is shared within women’s social networks in Uganda
(3) Provide detailed information on the timing and purpose of pregnancy termination disclosure

Uganda 2021-04-27 2024-04-27 Social Science and Humanities Non-degree Award
Martha Mulerwa
ID:
Inter-rater reliability and comparison of the repeatability of four different approaches to setting up goniometers and torsiometers to measure forearm and wrist kinematics.
REFNo: SIR60ES

General objective: Compare the four different approaches to setting up an electro-goniometer and torsiometer listed above in order to determine the most appropriate procedure for wrist kinematics measurements.

Specific Objectives:
To evaluate the repeatability of the four setup procedures
To evaluate inter-rater reliability when setting up the electro-goniometer and torsiometer using the four setup procedures during wrist kinematics
To evaluate intra-rater reliability when setting up the electro-goniometer and torsiometer using the four setup procedures during wrist kinematics

Uganda 2021-04-27 2024-04-27 Engineering and Technology Non-Clinical Trial Degree Award
Chaning Jang Ahn Wong
ID:
Contextualizing Moral Foundations Theory for Better Messaging in Uganda
REFNo: SS797ES

General Objective:
This study seeks to contextualize the Moral Foundation Theory to the Ugandan context through various instruments to have a better understanding of the social, and personal values of its population.
Specific and Achievable Objectives:
The breakdown of the general objective of this project is as follows:
Adapt the moral foundation research process, as laid out by Knutson and Haidt, to the Ugandan context through exploratory and confirmatory analysis
Diagnose the distribution of moral decision-making across five themes by examining respondents’ classifications of moral violations.
Seeking to understand how the foundations are distributed across the general population.
Use the validated set of moral foundations to inform behavioral change communication/messaging campaigns.

USA 2021-04-27 2024-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Enock Matovu
ID:
Development of Indirect Enzyme Linked Immunosorbent Assay [ELISA] for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Surveillance in Uganda
REFNo: HS1382ES

i. To evaluate commercially available formulations of the spike and nucleocapsid antigens derived from E. coli, insect and human cell expression systems to determine the best performer
ii. To determine the diagnostic sensitivity and specificity of the spike and nucleocapsid antigens-based indirect ELISA for diagnosis and community sero-surveillance of SARS-COV2

Uganda 2021-04-27 2024-04-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Roy Mayega William
ID: UNCST-2022-R010983
Differences in the formation and development of informal settlements and their effects on residents’ health and safety.
REFNo: SS715ES

General objective
The objective of the proposed research is to conduct formative research in Kampala, Uganda as part of a larger research agenda to compare informal settlements in four countries in East Africa, Uganda, Rwanda, Tanzania and Kenya to determine how history of formation, government strategies to improve settlements and the kinds of improvements that have been made affect the health and well-being of residents.
Specific objectives
Specific objectives of the proposed research include the following.
1. To explore how informal settlements in Kampala, Uganda are formed and how this may cause differences in the settlement’s health hazards.
2. formal To explore strategies that Uganda has taken to improve informal settlements and the health effects of these efforts for the families and children who live in informal settlements.
3. To qualitatively identify the most pressing health needs of families and children in the selected informal settlements within Kampala.

Uganda 2021-04-26 2024-04-26 Social Science and Humanities Non-degree Award
John Storey Douglas
ID:
Understanding factors that influence people's health-seeking behavior to inform a social and behavior change communications campaigns in Uganda
REFNo: SS761ES

The overall objective of this research is to suggest ways of improving the OBULAMU brand and to develop a set of recommendations
to inform a national-level social and behavior change communication strategy for the Ministry of Health in Uganda. In order to achieve this objective, the following smaller objectives will be met:
a)To identify the characteristics and behaviors of different brand users.
b)To understand the barriers and levers to improve past communication efforts.
c)To understand baseline attitudes, perceptions and the socio-ecological context which influences users' health-related decisions.
d)To identify the critical moments in people’s lives across which different health needs become salient
e)To design and test solutions to address the barriers faced by end-users and provide holistic recommendations that can inform the redesigning efforts of the OBULAMU campaign and provide inputs into the national SBC strategy.

USA 2021-04-26 2024-04-26 Social Science and Humanities Non-degree Award
Gerald Mboowa
ID:
Assessing knowledge, attitudes, perceptions, and skills towards the use of face masks: A community-level perspective
REFNo: SS489ES

i. To assess knowledge, attitudes, and perceptions towards the use of face masks by high- risk groups in Kampala district, Uganda.
ii. To assess skills towards the use of face masks, evaluate the face masks for safety and fitness-for-use, and provide a classification for those commonly circulating on the Ugandan market.
iii. To educate and skill high- risk groups in Kampala district on the rational use and disposal of face masks.

Uganda 2021-04-22 2024-04-22 Social Science and Humanities Non-degree Award
Lillian Tindyebwa --
ID:
Gender Dynamics - Analysis of Convicts in selected Prisons in Kigezi Region
REFNo: SS521ES

1. To explore gender dynamics of crimes for convicts in major prisons at selected districts in the Kigezi region
2.To identify types of crimes committed by men and women convicts in major prisons in the Kigezi region
3. To establish the gendered patterns formed in committing crimes by convicts in major prisons in the Kigezi region.
4.To explore the underlying motives to commit various crimes by the convicts in major prisons at districts in the Kigezi region.
5.To establish the influence of community that could cause the person to commit a crime.
Uganda 2021-04-22 2024-04-22 Social Science and Humanities Non-degree Award
Anthony Kadoma
ID:
Understanding stakeholder perceptions on wetland ecosystem services to support conservation and restoration activities
REFNo: SS705ES

To establish past, present, and future wetland conservation and restoration activities in Wakiso district

Identify the stakeholders involved and their roles and motivations

Document and analyze the perceptions stakeholders have on wetland ecosystem services and

To synthesize stakeholders' perceptions and their integration into wetland conservation and restoration activities.
Uganda 2021-04-22 2024-04-22 Social Science and Humanities Degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
Understanding differential effects of lipid lowering agents on lipid isoforms: a multi-center retrospective study in Uganda
REFNo: HS1292ES

a. To determine the patterns of dyslipidaemia among patients who present with dyslipidaemia at primary care and specialist hospitals in Uganda
b. To describe the patient characteristics that are associated with different patterns of dyslipidaemia
c. To determine the commonly used lipid lowering agents
d. To examine the differences in response to lipid lowering therapy
e. To determine the proportion of optimal control among individuals taking lipid-lowering agents
f. To examine the times to optimal LDL-C control among individuals taking lipid-lowering agents

Malawi 2021-04-22 2024-04-22 Medical and Health Sciences Non-degree Award
Elizabeth Brannon Lynn
ID:
The Role of Former Female Fighters in the National Resistance Movement
REFNo: SS791ES

During conflict, women step into a number of roles that were traditionally reserved for men--with some women joining rebel forces to fight, others taking up peace activism to combat such fighting, and many stepping into roles that were traditionally held by men. A strong literature has emerged detailing women's violent participation in conflict, as well as the motivations, dynamics, and implications of their action. Through their participation, women are able to experience greater equality with men, in addition to building critical skills and networks. However, little is known about how former rebel women build on these experiences post-conflict. Instead, much of the literature suggests that former rebel women experience significant marginalization after conflict, minimizing their future opportunities. Such patterns seem further at odds with patterns of rebel-group-to-political-party transformations. In this project, I have two main objectives. I seek to understand the post-conflict fate of former female fighters and how it relates to former rebel party politics. I ask if and how former female fighters are able to build on their conflict experiences and networks to access positions of political power in the post-conflict environment. Further, I seek to understand broader patterns in which women are elected after conflict. To understand these dynamics, I intend to collect systematic candidate data in Uganda and will complement this will a qualitative analysis based on interviews with former female combatants for the National Resistance Army.
USA 2021-04-22 2024-04-22 Social Science and Humanities Non-Clinical Trial Degree Award
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"A prosperous Science and Technology Led Ugandan Society."