Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Rebecca Nerima
ID: UNCST-2024-R015736
A QUALITATIVE STUDY EXPLORING FACTORS AFFECTING MULTIPLE MICRONUTRIENT SUPPLEMENTS (MMS) ADHERENCE AMONG PREGNANT WOMEN IN SOUTH CENTRAL AND BUSOGA REGION IN EASTERN UGANDA.
REFNo: HS5478ES

4. To make recommendations to public health stakeholders and decision-makers on strategies to enhance the uptake of MMS among pregnancy women in Uganda in the context of south and central Uganda.,3. Employ thematic analysis to examine healthcare providers\' perspectives on barriers and facilitators to pregnant women\'s adherence to MMS, as well as their insights into the strengths and weaknesses of existing strategies aimed at improving adherence.,2. Explore, through semi-structured interviews, the perspectives of healthcare providers in Uganda on factors influencing pregnant women\'s adherence to MMS, including their insights into the effectiveness and compliance of existing strategies, policies, interventions, and approaches.,1. 1. To explore existing knowledge on factors influencing pregnant women\'s adherence to multiple micronutrient supplementation.,
Uganda 2025-02-14 16:15:37 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
kamya Damiano Damiano
ID: UNCST-2024-R002433
"REMOTELY TEACHING CHILDREN WITH NEURODEVELOPMENTAL PROBLEMS: EXPERIENCES OF TEACHERS, SCHOOL MANAGERS AND PARENTS IN CENTRAL UGANDA"
REFNo: SS3556ES

Purpose of the Study.
The purpose of this study is to explore teachers’, school managers’ and parents’ experiences in remotely teaching children with neurodevelopmental problems in Central Uganda.
Specific Objectives
1. To examine,
a) teachers’
b) school managers’
c) and parents’ experiences on remotely taught children with neurodevelopmental problems.
2. To evaluate the opportunities of remotely teaching children with neurodevelopmental problems.
3. To examine the challenges faced by;
a) teachers
b) school managers
c) parents while remotely teaching children with neurodevelopmental problems.
4. To examine the interventions that can enhance experiences of remote teaching of children with neurodevelopmental problems.

Uganda 2025-02-14 16:10:11 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Gal Badihi
ID: UNCST-2024-R016596
Sociality and communication dynamics in grey-cheeked mangabeys (Lophocebus albigena) in the Bugoma Forest Reserve, Uganda
REFNo: NS911ES

The project aims to describe the communicative repertoire and social function of communication in grey-cheeked mangabeys
UK 2025-02-14 16:05:25 2028-02-14 Natural Sciences Non-Clinical Trial Non-degree Award
SAMSON OKUNG
ID: UNCST-2024-R003644
COMPETENCE-BASED TRAINING OF AUTOMOTIVE STUDENTS IN TECHNICAL TRAINING INSTITUTES IN THE EASTERN REGION OF UGANDA
REFNo: SIR434ES

(iv) To assess the financial adequacy on competence-based training of Automotive students in Uganda. , (iii) To establish the influence of human resource capacity on competence-based training of Automotive students in Uganda. ,(ii) To examine infrastructure relevance on competence-based training of Automotive students in Uganda.,(i) To determine the influence of instructional resources on competence-based training of Automotive students in Uganda.,The main objective is to investigate the effectiveness of competence-based training of automotive students in technical training institutes in the eastern region of Uganda.,
Uganda 2025-02-14 15:56:43 2028-02-14 Engineering and Technology Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of the Safety, Efficacy and Stability of SangaSupa®-30% Emulsifiable Concentrate [EC]: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricide Field Trial
REFNo: NS910ES

General objectives
To determine the efficacy, safety, and stability of SangaSupa® (Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control.
Specific objectives
The specific objectives of this acaricide field trial will to determine;-
i. efficacy of SangaSupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
ii. safety of Sangasupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
iii. Stability of Sangasupa® when applied onto cattle by plunge dipping for tick control.
Uganda 2025-02-14 15:53:01 2028-02-14 Natural Sciences Clinical Trial Non-degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
A Qualitative Study on Challenges and Opportunities for Non-Surgeons in Providing Inguinal Hernia Surgery in Uganda
REFNo: HS5363ES

To identify facilitators for non-surgeons in providing inguinal hernia surgery in Uganda.,To identify barriers for non-surgeons in providing inguinal hernia surgery in Uganda.,To identify existing barriers and facilitators in implementing task sharing for inguinal hernia surgery by non-surgeons and to explore potential strategies for enhancing surgical care delivery through task sharing in Uganda,To propose recommendations to further strengthen the quality of surgical task sharing in inguinal hernia repair in Uganda. ,
Sweden 2025-02-14 15:48:55 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
sharot kintu
ID: UNCST-2024-R016314
CARING FOR CHILDREN WITH SICKLE CELL DISEASE: A QUALITATIVE STUDY OF PARENTS/CAREGIVERS’ EXPERIENCES IN WAKISO DISTRICT
REFNo: SS3536ES

The study seeks to achieve four primary aims/objectives: 1.To understand and document the experiences of parents/carers in looking after children with SCD in Wakiso District. 2.To assess the ways in which the social cultural context in Wakiso affects the ability of the parents to care for children with SCD. 3.To explore the care related needs of the parents that can help them improve their role performance. 4.To identify SCD related with Gender Based violence against caregivers/parents in the community
Uganda 2025-02-14 15:44:16 2028-02-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Byamukama James Adonia
ID: UNCST-2024-R016133
Assessing the Distribution of Biological Indicators Along Altitude Gradient for Ecological Health of River Ishasha, western Uganda
REFNo: NS886ES

i) To document the anthropogenic activities along the altitude gradient of River Ishasha
ii) To determine selected physicochemical parameter along altitude gradient of River Ishasha
iii) To determine the distribution of periphytons and macro-invertebrates along altitude gradient of River Ishasha
Uganda 2025-02-14 15:36:06 2028-02-14 Natural Sciences Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Exploring gendered pathways to strengthen the involvement of TB survivors in the Uganda TB response: A Photovoice Study
REFNo: HS5241ES

General objective The aim of this study is to identify gendered pathways for strengthening the involvement of TB survivors, including from key populations1, in the TB response by documenting opportunities, challenges, and preferences to meaningful engagement from the perspective of female and male TB survivors in urban Central Uganda region. Specific objectives The specific objectives of this study are: Objective 1: To use photovoice as a platform for female and male TB survivors to visualise/document their contributions towards ending TB in their families and communities in urban Central Uganda (Q1). Objective 2: To engage female and male TB survivors in photovoice to explore the challenges they face in their efforts to end TB in their families and communities in urban Central Uganda (Q2). Objective 3: To use photovoice as a vehicle for female and male TB survivors to document their preferences for their meaningful involvement in the TB response in urban Central Uganda (Q3-4). Objective 4: To facilitate dialogue between photovoice participants and TB survivors on the photo stories to identify steps towards creating a gender-responsive supportive environment for TB survivors’ actions towards ending TB in Central Uganda (Q5-6). Objective 5: To assess the benefits and challenges of applying photovoice methodology to identify and promote gendered pathways for the meaningful involvement of TB survivors (Q7).
Uganda 2025-02-14 15:34:56 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayomide Atoki Victor
ID: UNCST-2022-R008808
BIOMEDICAL EVALUATION OF HESPERIDIN AND NARINGENIN ON NEUROLOGICAL INDICES IN DROSOPHILA MELANOGASTER MODEL OF ALZHEIMER’S DISEASE
REFNo: HS3813ES

Assess the expression of genes relevant to neuronal function in flavonoid-treated flies,Evaluate quantitatively the level of amyloid precursor protein in the flies,Determine the influence of Hesperidin and Naringenin on in vivo antioxidant status in the flies,Assess the effect of Hesperidin and Naringenin on activities of critical enzymes relevant to Alzheimer’s disease in the flies ,Evaluate the effect of Hesperidin and Naringenin on geotaxis, memory and life span in both wild (Harwich strain) and transgenic (Bloomington stock P{UAS-APP695-N-MYC}, P{UAS:BACE1}) Drosophila melanogaster,The main objective of the study is to assess the effect of Hesperidin and Naringenin on biomarkers of neurodegeneration in transgenic D. melanogaster model of Alzheimer’s disease.,
Nigeria 2025-02-14 15:22:49 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
Reducing hazardous alcohol use and optimizing treatment as prevention among men living with HIV in risk environments
REFNo: HS5558ES

Understand barriers and facilitators in the inner and outer context for implementing the components of Kisoboka within the routine clinical setting to inform future widespread implementation guided by the Exploration, Preparation, Implementation and Sustainment (EPIS) framework and documentation of intervention and implementation costs. ,Assess the impact of the Kisoboka intervention and its components on measures of psychological, physical, and socioeconomic well-being that capture frequent comorbidities of people living with HIV and are associated with achieving successful treatment as prevention,Determine the efficacy of the Kisoboka intervention and its components on alcohol and HIV outcomes among hazardously drinking men living with HIV in Uganda in a 2x2 factorial RCT. ,Assess the efficacy of Kisoboka and its components (BE & MI) to gain insight into Kisoboka’s potential effect, determine if BE and MI interact and examine barriers and facilitators for implementing Kisoboka within routine clinical settings to inform future widespread implementation.,
Uganda 2025-02-14 15:19:41 2028-02-14 Medical and Health Sciences Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
A Prospective, Clinical Trial Examining the Immune Response of Participants Receiving Modified Vaccinia Ankara (MVA) Vaccine in Africa,”-Mpox Vax Africa
REFNo: HS5575ES

To determine:

the development of MVA-BN-specific antibodies at week 6 post-first vaccination with MVA-BN in
a population recruited in Africa, and compare to a population recruited in Europe.

Durability of MVA-BN-specific antibodies at week 24 post-first vaccination with MVA-BN.
● Factors associated with MVA-BN-specific antibody responses at week 48 post-first
vaccination with MVA-BN.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination between a
population recruited in Africa and a population recruited in Europe.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination with MVA-BN in
understudied populations (women and PLWH).
● Prevalence of asymptomatic seroconversion to mpox by week 48 post-first vaccination
Uganda 2025-02-08 13:35:10 2028-02-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
THE SECOND UGANDA TB PREVALENCE SURVEY (TBPS2)
REFNo: HS5269ES

Estimating the sizes of key and vulnerable TB populations as defined in the national gender and key and vulnerable populations assessment report nationally and sub nationally,Evaluating factors associated with TB including HIV, diabetes, undernutrition, tobacco smoking, alcohol ab use, and socio-economic status,,Updating population-based estimates of TB burden using results from the prevalence survey ,Assessing healthcare-seeking behaviors and understand where individuals with TB symptoms seek medical care,The secondary objectives of TBPS2 in Uganda encompass: The prevalence of symptoms suggestive of pulmonary tuberculosis (PTB) and determining radiological abnormalities among individuals aged ≥15 years, ,The primary objective is to determine the national and subnational prevalence of bacteriologically confirmed pulmonary TB among the general population aged ≥15 years,The goal of the survey is to enable the country (MOH/NTLP and partners) to gain a better understanding of the current burden of TB, health-seeking behavior and health system response in order to identify ways of improving TB programming towards ending TB in the country.,
Uganda 2025-02-07 18:27:07 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DANIEL KIIZA
ID: UNCST-2024-R004044
Retrospective chart review of patients with Laboratory-Confirmed Sudan Virus Disease Hospitalized in Two Ebola Disease Treatment Units in Uganda (September 2022 to January 2023)
REFNo: HS5541ES

To evaluate the safety and clinical course of patients receiving investigational treatments for SVD,To identify host and disease factors associated with outcomes from SVD,To characterize the natural history and outcomes of Sudan virus disease (SVD) among hospitalized patients with RT-PCR detected Orthoebolavirus sudanense (SUDV) RNA,
Uganda 2025-02-07 18:10:59 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
AN OUTCOME RESEARCH ON THE WESTERN UGANDA BANTWANA PROGRAM ON VIOLENCE AGAINST CHILDREN IN SCHOOLS AND SURROUNDING COMMUNITIES (VACiSC) IN THE THREE DISTRICTS OF KABAROLE, KYENJOJO and BUNYANGABU
REFNo: SS3625ES

The study aims to assess the effectiveness of the Western Uganda Bantwana Program (WUBP) in preventing and responding to Violence Against Children (VAC), including child sexual abuse (CSA), in schools and surrounding communities in the three Districts of Kabarole, Kyenjojo, and Bunyangabu

Specific Objectives
1. To measure the change in knowledge, attitude and practices on risks exposures to VACiSC including CSA with focus on prevention and response among children, young adults, caregivers and teachers.
2. To assess how the WUBP aligned to the needs of communities and existing practices (structures and approaches) on prevention and response to VACiSC including CSA.
3. To evaluate the role of caregivers, teachers, para-social workers, and community leaders in creating and maintaining safe environments for children.

Uganda 2025-02-07 18:09:14 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eva Smallegange Sophia
ID: UNCST-2023-R005788
Effectiveness of PlayMatters in Uganda: a teacher professional development programme aiming to integrate Learning through Play as pedagogical approach in the classroom
REFNo: SS3617ES

1. To study the effectiveness of PlayMatters Teacher professional Development program on teacher practices and teacher wellbeing.
2. To study how do the effects of the intervention vary by teachers’ age, gender, displacement status, level of education and professional experience?
3. To study how do effects of the intervention vary by differences in adherence to implementation of the Teacher Continuous Professional Development (TCPD) component of the intervention?
4. To study the effectiveness of the PlayMatters Teacher professional Development program at child outcome level (cognitive, social, emotional, physical and creative skills and on their mental health and wellbeing).
5.To study the cost-effectiveness of the PlayMatters intervention.
Netherlands 2025-02-07 18:07:38 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Evaluation of the One Acre Fund project - making 34,000 coffee farmers more resilient by 2027
REFNo: A560ES

To establish whether all household members are equally benefiting from the impacts of the project and how? ,To determine which pursued pathways of change are the main drivers in delivering outcome and impact? ,To establish the causal effects of the project for direct project participants? ,
Uganda 2025-02-07 18:04:15 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Michelle Brown
ID: UNCST-2022-R009670
Describing the vocal repertoire of L’Hoest’s monkeys
REFNo: NS410ES

To test whether L’Hoest’s monkeys (Allochrocebus lhoesti) contradict the ‘social complexity hypothesis’ by determining whether they communicate in frequencies too low for human hearing.
USA 2025-02-07 18:02:59 2028-02-07 Natural Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Incidence and economic impacts of bovine mastitis in smallholder dairy farms in Kenya and Uganda
REFNo: A564ES

To assess knowledge of bovine mastitis, its control and treatment among smallholder dairy farmers.
To assess the effectiveness of using cell phone technology as a method of disseminating information on udder health to farmers.
To estimate the incidence rate of clinical and subclinical mastitis among recently-calved dairy cows (≤4 weeks prior to baseline data collection).
To determine the drivers of bovine mastitis among sampled dairy cows.
To estimate the monthly and annual financial losses attributed to clinical and subclinical mastitis.
Uganda 2025-02-07 18:01:56 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Assessment of the functionality of health unit management committees in primary healthcare health facilities in Uganda: a case of health center IIIs
REFNo: HS5407ES

a) To determine the presence and functionality of HUMCs in HCIIIs
b) To determine the factors influencing the functionality status of HUMCs in HCIIIs
c) To identify any interventions needed to strengthen the performance of HUMCs in HCIIIs.

Uganda 2025-02-07 17:59:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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