Karolina Werner
ID:
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From Statebuilding to Localized Governance: Exploring African governance structures
REFNo: SS56ES
The project focuses on understanding the legal integration of informal/traditional authorities into the governance of states in sub-Saharan Africa. The objective is to better understand the unique systems of governance present on the continent, providing a comparative study of four countries (Uganda, Zambia, Mozambique, Botswana) with varying degrees of integration.
|
Canada |
2018-02-13 |
2021-02-13 |
Social Science and Humanities |
|
Degree Award |
|
Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
|
Implementation and Adaptation of a Web-Based Clinical Education Program for Mental Health Providers in Uganda
REFNo: HS59ES
The objective of the study is to assess the acceptability and utility a of western-developed online CBT course in advancing knowledge of cognitive-behavioral interventions among staff and graduate students in the department of psychiatry at Mbarara University/Mbarara Hospital in southwestern Uganda. Because this is the first time the course is being offered in this manner in Uganda, it is necessary to first pilot and adapt the training modules to our local setting.
|
Uganda |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
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Non-degree Award |
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Anna Stadelman Michelle
ID:
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Assessing Lung Function and Quality of Life in Ugandans after Completion of Multi-Drug Resistant Tuberculosis Treatment (ALFU-MDR TB)
REFNo: HS122ES
To evaluate the impact of MDR TB and its treatment on pulmonary
function in survivors of MDR TB.
To establish the impact of MDR TB and its treatment on the quality of life
of MDR TB survivors.
To assess the effect of HIV and MDR TB co-infection on pulmonary
function in MDR TB survivors.
|
USA |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Yahaya Gavamukulya
ID: UNCST-2019-R001017
|
Green Synthesis and Biochemical Evaluation of Anticancer Activities of Silver Nanoparticles Conjugated Ethanolic Extracts of Leaves of Annona muricata (Graviola)
REFNo: NS43ES
General Objective
To undertake green synthesis and biochemical evaluation of anticancer activities of AgNPs-conjugated ethanolic extracts of leaves of Annona muricata (Graviola).
Specific Objectives
1. To conduct LCMS analysis of the ethanolic extracts of leaves of Annona muricata and undertake green synthesis and characterization of the extracts’ mediated AgNPs.
2. To investigate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the biological properties (morphology, migration, growth, and death) of selected cancer cell lines using selected assays.
3. To evaluate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the transcriptome for expression of cancer associated genes in selected cancer cell lines using RNA-Seq analysis.
4. Evaluation of the in vivo anticancer activities of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata against chemically induced tumours in mice models.
|
Uganda |
2018-02-13 |
2021-02-13 |
Natural Sciences |
|
Degree Award |
|
Helen Liebling Jane
ID:
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Sexual and Gender-Based Violence and Torture Experiences of South Sudanese Refugees in Northern Uganda: Health and Justice Responses
REFNo: SS126ES
Specific objectives are to:(1) examine the experiences of South Sudanese refugees and impact of Sexual and Gender-Based Violence (SGBV) and torture on their lives (2) analyse reproductive and psychological health,and justice needs of refugees from their own and service providers’ perspectives
and (3) evaluate responses to refugees by state justice, health services and key
stakeholders.
|
UK |
2018-02-13 |
2021-02-13 |
Social Science and Humanities |
|
Non-degree Award |
|
Helen Byakwaga
ID: UNCST-2019-R001168
|
Study of Newly Diagnosed Kaposi's Sarcoma
REFNo: HS157ES
1) Describe the clinical and laboratory characteristics of HIV-infected patients who develop KS.
2) Determine survival after KS occurrence in both ART-treated and ART-untreated HIV-infected patients.
|
Uganda |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Stephen Kyakulumbye
ID:
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A framework for developing citizen-centric e-government applications in developing contexts: The design-reality gap
REFNo: IS9ES
To document a feasible participatory design methodology for citizen e-government applications.
|
Uganda |
2018-02-13 |
2021-02-13 |
Social Science and Humanities |
|
Degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
Steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily in the presence of rifampicin and isoniazid (Rifinah or the local generics)
REFNo: HS161ES
Primary Objective: To evaluate the steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic)
Secondary Objectives:
1. To assess the safety and tolerability of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic)
2. To investigate the association between genetic polymorphisms in drug disposition genes and drug exposure.
|
Nigeria |
2018-02-06 |
2021-02-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
A PHARMACOKINETIC EVALUATION OF ETONOGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-I)
REFNo: HS145ES
Primary objective:
To compare the PK of ENG (68 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls
Secondary objectives:
(1) To predict the disposition of ENG over the subsequent 2.5 years of intended use through PK modeling of ENG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART
(2) To describe the PK exposure over 12 months of ENG contraceptive implant in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART
(3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with ENG.
(4) To describe the safety and tolerability of combined use of DRV/RTV or RPV and ENG during 12 months of combined use.
(5) To describe the relationship between ENG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
|
Nigeria |
2018-01-29 |
2021-01-29 |
Medical and Health Sciences |
|
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
A PHARMACOKINETIC EVALUATION OF LEVONORGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-II)
REFNo: HS146ES
Primary objective: To compare the PK of LNG (150 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls.
Secondary objectives:
(1) To compare the PK of LNG over 12 months among women receiving DRV-based ART or RPV-based ART versus historical controls
(2) To predict the disposition of LNG over the subsequent 4 years of intended use through PK modeling of LNG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART
(3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with LNG.
(4) To describe the safety and tolerability of combined use of DRV/r or RPV and LNG during 12 months of combined use.
(5) To describe the relationship between LNG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
|
Nigeria |
2018-01-29 |
2021-01-29 |
Medical and Health Sciences |
|
Non-degree Award |
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