Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
An Open-label, Single-arm Study to Provide Continued Access to Study Drug to Participants Who Have Completed Pediatric Clinical Studies Involving Gilead HIV Treatments.
REFNo: HS5804ES

The primary objective of this trial is to provide continued access to the study medication received in the parent protocol or switch to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF; coformulated; Biktarvy®) for participants who completed a Gilead parent study evaluating medications for HIV treatment.
Uganda 2025-04-11 16:20:58 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
STEPHEN DUSENGIMANA
ID: UNCST-2025-R017043
COST MANAGEMENT PRACTICES AND FINANCIAL PERFORMANCE OF PRIVATE SECONDARY SCHOOLS IN UGANDA: ACASE STUDY OF KAGADI DISTRICT, WESTERN REGION
REFNo: SS3722ES

1. To assess the contribution of budgeting in terms of Timeliness, Variance Analysis, transparency on financial performance of Private Secondary Schools in Kagadi District, western region, Uganda
2. To examine the effect of Financial reporting in terms of completeness, compliance and consistency on financial performance of Private Secondary Schools in Kagadi District, western region, Uganda
3. To analyze the level of cost control in terms of cost reduction and cost variance on financial performance of Private secondary schools Kagadi District, western region, Uganda
4. To investigate the moderating effect on the relationship between cost management practices and financial performance of private secondary schools in Kagadi, western region, Uganda

Uganda 2025-04-11 16:07:56 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
TESTING MULTI-LEVEL SCALE-UP STRATEGIES TO IMPLEMENT A SCHOOL-BASED POPULATION APPROACH OF MENTAL HEALTH PREVENTIVE INTERVENTION: UGANDA
REFNo: HS5647ES

General Objective
The overall goal of this study is to address vertical and horizontal scale-up implementation framework gaps in Uganda. This study will test new recommended vertical scale-up and sustainability implementation strategies and study impact and underlying mechanisms when the new scale-up model is applied.
This research will guide the development of evidence-informed theoretical frameworks and processes to effectively institutionalize EBIs in LMICs such as Uganda. To achieve this goal, we will carry out 4 sequential steps (4 aims).
Specific Objectives
1.
To establish a cross-level partnership and strengthen stakeholders/leaders’ advocacy capacity to make evidence-based informed children’s mental health policy and practice decisions and to facilitate the EBI institutionalization through the educations system illustrated in figure 1.
2.
To develop implementation Protocols in collaboration with cross level partners (established in Aim 1) based on a new multilevel train-the-trainer scale-up framework to support the EBI/PD scale-up.
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3.
Implement the new Protocols for scale-up and test the relative value of additional implementation supports intended to sustain teacher EBI practices through a Hybrid III cRCT.
4.
To explore underlying scale-up and sustainability implementation mechanisms.
Uganda 2025-04-11 16:03:54 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
Impact Evaluation of Childcare Services for Kampala Market Women Study
REFNo: SS3696ES

Primary objectives:
a. To assess the labour market effects (labour force participation and productivity) of gaining access to childcare services by women working in markets in Kampala.
b. To assess the effects of gaining access to childcare services on the well-being of women working in markets in Kampala.
c. To assess the effects of gaining access to childcare services on the well-being of children of women working in markets in Kampala.

Secondary objective:
d. To assess important dimensions of heterogeneity, related to accessibility, wealth levels, women’s agency, and child’s age.
e. To explore secondary outcomes of access to childcare services by women working in markets in Kampala including spillover effects on other household members, and changes in mobility.


Uganda 2025-04-11 16:00:39 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deborah Nakalyowa Luggya
ID: UNCST-2024-R003382
Menstrual Hygiene Management and materials: Experiences of Adolescent Girls with Disability in Kamuli District, Uganda
REFNo: SS3523ES

a) To examine the current state of menstrual hygiene management among adolescent girls with disabilities in Kamuli district.
b) To identify the unique needs and challenges of adolescent girls with different disabilities in managing menstruation in Kamuli district.
c) To assess the factors influencing availability, accessibility, and affordability of reusable sanitary wear for adolescent girls with disabilities in Kamuli district.
d) To explore the socio-cultural factors influencing menstrual hygiene practices among adolescents with disabilities in Kamuli district.
e) To assess the effects of inadequate menstrual hygiene management on the overall health, well-being, and participation of adolescent girls with disabilities in Kamuli district.

Uganda 2025-04-11 15:55:45 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
ATURINDA JOSHUA
ID: UNCST-2024-R002017
NARRATIVES OF RESILIENCE: KIGA FOLKTALES IN CULTIVATING SUSTAINABLE CULTURAL IDENTITY
REFNo: SS3803ES

i. To establish the historical moral and educational value embedded within Kiga traditional folktales.
ii. To analyze the importance of Kiga folktales in cultivating sustainable Cultural Identity
iii. To design innovative interventions that ensure sustainability of traditional Kiga folktales.

Uganda 2025-04-11 15:53:53 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Okethwangu
ID: UNCST-2024-R004883
Health system resilience in the context of infectious disease outbreaks: Exploring concepts and experiences, frameworks and tools in Uganda
REFNo: HS5718ES

1. Explore the understanding of the concept of health systems resilience, and determinants that influence building a health system resilient to infectious disease epidemics in Africa.
2. Critically assess the JEE and GHSI tools for their appropriateness to measure resilience to infectious disease outbreaks in Uganda and based on the results adapt/develop a context-specific tool for measuring HSR to infectious disease outbreaks.
3. Assess the resilience of the health systems of Mubende and Kassanda Districts during response to the Ebola virus disease outbreak in 2022 using the context-specific tool and design interventions or strategies to address identified gaps towards building a resilient health systems to infectious disease outbreaks.
4. Identify enablers and barriers to the implementation of proposed strategies and interventions aimed at building a resilient health system to infectious disease epidemics.
Uganda 2025-04-11 15:28:50 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Awal
ID: UNCST-2024-R016231
DEVELOPMENT OF POWER FLOW ANALYSIS TECHNIQUE OF 132-KV POWER TRANSMISSION GRID: A CASE STUDY OF UGANDA\'S ELECTRIC POWER SECTOR
REFNo: SIR483ES

PID parameter optimization using water cycle algorithm (WCA).,The current state of AGC in interconnected power systems.,
Uganda 2025-04-11 15:27:19 2028-04-11 Engineering and Technology Non-Clinical Trial Degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
PERFORMANCE OF SELECTED NOVEL MOLECULAR POINT OF CARE DIAGNOSTICS FOR EMERGING AND ONGOING EPIDEMICS AND ANTIMICROBIAL RESISTANCE IN UGANDA (PREPARE-TID)
REFNo: A584ES

General Objective To validate novel rapid molecular assays in nucleic acid extraction, point of care testing and One health surveillance of AMR, CCHF, RVF and other arthropod borne pathogens responsible for emerging and ongoing epidemics in Uganda Specific Objectives (i) To determine the prevalence of Congo Crimean Haemorrhagic fever (CCHF) in different tick species collected at Kampala City Abattoir. (ii) To determine the diagnostic performance of a novel NA extraction on selected Assays for rapid detection of CCHF, RVF and AMR. (iii) To determine the diagnostic performance the multiplex qPCR-based Point of Care diagnostic assay for detection of CCHF, RVF and AMR. iv) To appraise the existing one health point of care diagnostics for detection of zoonotic pathogens using a meta-analysis. (v) To determine the reliability of novel next generation sequencing platform for detection of AMR markers for Staphylococcus aureus, E. coli, Klebsiella, Pseudomonas aeruginosa from waste water samples.
(vi) To document the conditions required for the optimal performance of the test protocols.
(vii) To evaluate the field performance of the Multiplex qPCR one Health point of care diagnostic and the reliability of novel Next Generation platform in an emergency outbreak situation.

Uganda 2025-04-11 15:16:42 2028-04-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Dialogues of Delivery: Fine-Tuning Large Language Models for Prenatal and Perinatal Care in East African Languages
REFNo: HS5739ES

General Objective
To develop, evaluate, and deploy an open-source fine-tuned Large Language Model capable of answering prenatal and perinatal care questions in Luganda, Runyankore-Rukiga, and Swahili, thereby enhancing access to relevant health information among expectant mothers.
Specific Objectives
1. Collect, curate, and build high-quality clinical text corpora and datasets specific to these languages and healthcare needs.
2. Develop a pipeline for fine-tuning domain-specific LLMs to support prenatal and perinatal care in Luganda, Runyankore-Rukiga, and Swahili.
3. Deploy and evaluate the effectiveness of the fine-tuned domain-specific LLMs in community health settings, ensuring linguistic, cultural, and contextual relevance.

Uganda 2025-04-11 15:13:35 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Omulepu Isaac
ID: UNCST-2022-R003531
PREVALENCE AND FACILITATORS OF RESPECTFUL MATERNITY CARE DURING CHILDBIRTH AMONG WOMEN IN IN KAYUNGA REGIONAL REFERRAL HOSPITAL AND IMPACT OF DISRESPECTFUL AND ABUSIVE CARE ON MATERNAL HEALTH SEEKING BEHAVIOR
REFNo: HS5710ES

1. To determine the prevalence of RMC during childbirth among women in Kayunga RRH .
2. To assess for the facilitators of RMC during childbirth among women in Kayunga RRH
3. To explore the impact of disrespectful and abusive care of women during childbirth to maternal health seeking behavior.

Uganda 2025-04-11 14:48:37 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nicolas Laing
ID: UNCST-2024-R015317
The impact of patient preferences, knowledge and attitudes on the demand for and supply of formal health care in Uganda
REFNo: SS3699ES

Objecitve,
New Zealand 2025-04-11 14:45:57 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Japheth Noel
ID: UNCST-2021-R013959
The Role of Inclusive Practices on Academic Resilience and Retention among Refugee Secondary School Students: A case of Nakivale Refugee Settlement Camp, Uganda
REFNo: SS3750ES

To examine the role of inclusive practices on academic resilience and retention among refugee secondary school students in Nakivale refugee settlement camp in Uganda.,(v) To analyze the relationship between academic inclusive practices and retention among secondary school students in Nakivale refugee settlement camp.,To determine the relationship between social inclusive practices and retention among secondary school students in Nakivale refugee settlement camp.,To analyze the relationship between academic inclusive practices and academic resilience among secondary school students in Nakivale refugee settlement camp.,To examine relationship between social inclusive practices and academic resilience among secondary school students in Nakivale refugee settlement camp.,To explore social and academic inclusive practices among secondary schools in Nakivale refugee settlement camp, in Uganda.,
Uganda 2025-04-11 14:40:49 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
EDWIN AKUGIZIBWE
ID: UNCST-2024-R003785
Data-driven trauma and surgery care in remote Africa: Socioeconomic insights, outcome models and equity recommendations
REFNo: SS3606ES

Develop an innovative app to enhance tracking and prediction of follow-up-treatment of trauma/surgery cases for improved health equity in Uganda and Africa at large.,Identify patterns and trends and develop models that classify and predict trauma related cases, with a particular focus on disparities in healthcare delivery.,Assess the impact of socioeconomic factors on access to surgical care for trauma patients in remote regions of Uganda ,The key aim of this study is to develop predictive models for health equity in remote African regions. These models will integrate data on SES, healthcare infrastructure, and past healthcare outcomes to anticipate potential areas of need and vulnerability (Ranapurwala et al., 2019). By proactively identifying and addressing disparities, the study seeks to contribute to the establishment of a more equitable and resilient healthcare system capable of responding effectively to trauma incidents.,
Uganda 2025-04-11 14:37:25 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Ebbs
ID: UNCST-2021-R012328
A Risk Prediction Model for Prehospital Identification of Seriously Ill Children in Resource Limited Settings
REFNo: HS5672ES

Develop a risk prediction model for the early identification of serious illness in the prehospital setting. , Determine the ability of CHWs to collect new clinical exam parameters in the prehospital setting utilizing mHealth for training. ,
USA 2025-04-11 14:34:43 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tadeo Winyi
ID: UNCST-2024-R002357
FINANCIAL RESOURCE MANAGEMENT AND THE QUALITY OF EDUCATION IN HIGHER INSTITUTIONS: A CASE OF PRIVATE UNIVERSITIES IN CENTRAL UGANDA
REFNo: SS3719ES

The study's objectives are:
i. To assess the role of revenue streams in promoting quality of education in private universities in central Uganda.
ii. To determine the extent to which financial budgeting influences the quality of education in private universities in central Uganda.
iii. To analyze the effect of financial monitoring and control in the promotion of quality of education in private universities in central Uganda.
iv. To explore the mediating role of financial management practices between financial resource management and quality of education in private universities in central Uganda.


Uganda 2025-04-11 14:31:27 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
FRED TWINOMUGISHA
ID: UNCST-2024-R003414
THE ROLE OF INVOLVING PATIENTS IN PROMOTING HAND HYGIENE PRACTICES AMONG HEALTHCARE WORKERS IN MUKONO AND KAGADI DISTRICTS: A MIXED METHODS STUDY
REFNo: HS5449ES

1)To determine the level of knowledge and practice on hand hygiene among patients and health workers in selected healthcare facilities in Mukono and Kagadi districts, Uganda.
2)To explore the barriers and facilitators of involving patients in promoting hand hygiene practices among healthcare workers in selected healthcare facilities in Mukono and Kagadi districts, Uganda.
3)To explore the perceptions of healthcare workers on involving of patients in promoting hand hygiene practices in selected healthcare facilities in Mukono and Kagadi districts, Uganda.
4)To design and evaluate an intervention to improve hand hygiene among health workers.

Uganda 2025-04-11 14:30:15 2028-04-11 Medical and Health Sciences Clinical Trial Degree Award
Jessica Perkins M
ID: UNCST-2021-R013564
Perceived Norms About Alcohol Use and HIV/STI Prevention among Adolescents and Young Adults in Rural Uganda (Y-SNAPS)
REFNo: HS5650ES

1. To Use qualitative methods to explore perceived norms around alcohol, HIV/STI transmission risk behavior, and HIV prevention among adolescents and young adults (AYA) in Rwampara District, Uganda. 2. To estimate the causal effects of perceived norms around alcohol use and HIV/STI transmission risk behavior on HIV/STI prevention among AYA in Rwampara District and conduct survey experiments to assess how different data collection methods affect responses. 3. To conduct a mixed-methods, randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among AYA in Rwampara District.
USA 2025-04-11 14:27:29 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Namakula
ID: UNCST-2022-R006923
Antibiotic prescription patterns among inpatients at Mulago National Referral Hospital, Uganda. Incidence, UCG compliance and associated factors
REFNo: HS5646ES

To determine the incidence of antibiotic prescription among inpatients at Mulago National Referral Hospital, Uganda.
Uganda 2025-04-11 14:26:00 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lucy Aciro
ID: UNCST-2023-R007829
Income Diversification and Climate Change Adaptation among smallholder farmer in Northern Uganda
REFNo: A567ES

1. To determine the alternative livelihood strategies among smallholder wood charcoal producers
2. To analyze the effect of income diversification options on food security and living standards of the smallholder wood charcoal producers
3. To assess the climate change adaptation strategies adopted by smallholder wood charcoal producers
4. To determine the willingness of the farmers to adopt different strategies or productions process that enhances sustainability

Uganda 2025-04-11 14:24:32 2028-04-11 Agricultural Sciences Non-Clinical Trial Degree Award
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