Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Napyo Kasede Agnes
ID:
UNIVERSAL ANTIRETROVIRAL THERAPY FOR ELIMINATION OF MOTHER-TO-CHILD TRANSMISSION OF HIV IN LIRA, NORTHERN UGANDA: DETERMINANTS, ADHERENCE, BREASTFEEDING AND VIRAL LOAD
REFNo: HS222ES

1. To determine the prevalence and factors associated with facility deliveries among HIV+ pregnant women receiving antenatal care in Lira Regional Referral Hospital, Lira district 2. To estimate the proportion of babies born to HIV+ mothers that adhere to nevirapine prophylaxis and identify factors contributing to their non-adherence in Lira District. 3. To determine the prevalence and factors associated with exclusive breastfeeding at 14 weeks among HIV+ women enrolled on Option B+ in Lira district. 4. To find out the proportion of HIV+ pregnant women that are virally suppressed and factors associated with viral non-suppression
Uganda 2018-09-24 2021-09-24 Medical and Health Sciences Degree Award
Stanley Asaku Tom
ID:
Perceived Social and Behavioural Determinants of Preventive Health Behaviour among Undergraduate Female Students at Makerere University, Uganda: A cross-sectional study
REFNo: HS229ES

i)To determine and compare the extents to which perceived threats visavie benefits, influence the likelihood of PHB adoption among undergraduate female students at Makerere University. ii)To identify perceived social barriers to PHB adoption among undergraduate female students at Makerere University. iii) To identify self-efficacy perceptions and efficacious cues to action for enhanced adoption of PHB at Makerere University. The study aims to gain an understanding of undergraduate female students’ social and behavioral perceptions that tend to influence the likelihood of adopting multiple preventive health behaviors (PHB).
Uganda 2018-09-24 2021-09-24 Medical and Health Sciences Degree Award
Frederik Leerhoei
ID:
An Assessment Of Entomological Diversity And The Effect of Organic Coffee Farming on Biodiversity In South Western Uganda Along A National Park Gradient.
REFNo: NS63ES

We will go to Bwindi Forest Farm in Uganda to investigate the effects on agro- organic farming. This will be done to analyse what best ways to conserve nature amidst a growing population taking up more space for settlement and agriculture. Here we will look at how effective organic coffee farming is compared to conventional farming in terms of biodiversity seen, incorporation of pollinators and the reduction of coffee's worst enemy, the coffee borer beetle. In this case you will help to support a project where data is collected about renewal of conventional farming into a more agro-organic approach. Project 1 - One of our goals is to investigate how well it is to practice organic farming in relation to conventional agriculture as regards to what supports biodiversity best. In relation to this, we will do some specific studies on the entomologi around organic and conventionel coffee plantations as coffee has a huge economic and cultural significance worldwide. This will be done during the dry season running from september till November and during the rainy season running from November til December. Project 2 - In this project, we look at one of the coffee plant's biggest enemies, Coffee Borer Beetle, which is a pest that drills into coffee beans and lays eggs in it. These beetles have some enemies, which are parasitoid wasps that naturally fight these pests. Here we will examine whether organic or conventional coffee cultivation is most effective in the natural control of these pests, and in this context where the greatest biodiversity of these wasps occurs. The collection of coffee berries will be done 30 different coffee plants on different conventional and organic farms. This will be done during harvest season of ripe coffee berries in October and as well when the immature green berries show up to see if there are seasonal differences in pest presence. Project 3 - In addition, we will look at the effect of organically grown coffee on pollinators of the plant, such as bees, and the conditions that best benefit them. This is done as the number of pollinators worldwide is in decrease, which is a huge problem since pollination- dependent crops, such as the coffee plant, contribute 35 percent of the global crop production volume. This can have a huge impact on the yield and quality of the product, depending on whether it is an organic or conventional farm. This follows the same timeline as project 1.
Denmark 2018-09-24 2021-09-24 Natural Sciences Degree Award
Daniel Oeksnebjerg Bilyeli
ID:
"An Assessment Of Entomological Diversity And The Effect Of Organic Coffee Farming On Biodiversity In South Western Uganda Along A National Park Gradient. "
REFNo: NS64ES

We will go to Bwindi Forest Farm in Uganda to investigate the effects on agro- organic farming. This will be done to analyse what best ways to conserve nature amidst a growing population taking up more space for settlement and agriculture. Here we will look at how effective organic coffee farming is compared to conventional farming in terms of biodiversity seen, incorporation of pollinators and the reduction of coffee's worst enemy, the coffee borer beetle. In this case you will help to support a project where data is collected about renewal of conventional farming into a more agro-organic approach. Project 1 - One of our goals is to investigate how well it is to practice organic farming in relation to conventional agriculture as regards to what supports biodiversity best. In relation to this, we will do some specific studies on the entomologi around organic and conventional coffee plantations as coffee has a huge economic and cultural significance worldwide. This will be done during the dry season running from september till November and during part of the rainy season running from November til Denmark . Project 2 - In this project, we look at one of the coffee plant's biggest enemies, Coffee Borer Beetle, which is a pest that drills into coffee beans and lays eggs in it. These beetles have some enemies, which are parasitoid wasps that naturally fight these pests. Here we will examine whether organic or conventional coffee cultivation is most effective in the natural control of these pests, and in this context where the greatest biodiversity of these wasps occurs. The collection of coffee berries will be done 10 times from 30 different coffee plants on an number of conventional and organic farms. This will be done during harvest season of ripe coffee berries in October and as well when the immature green berries show up to see if there are seasonal differences in pest presence. Project 3 - In addition, we will look at the effect of organically grown coffee on pollinators of the plant, such as bees, and the conditions that best benefit them. This is done as the number of pollinators worldwide is in decrease, which is a huge problem since pollination-dependent crops, such as the coffee plant, contribute 35 percent of the global crop production volume. This can have a huge impact on the yield and quality of the product, depending on whether it is an organic or conventional farm. This follows the same timeline as project 1.
Denmark 2018-09-24 2021-09-24 Natural Sciences Degree Award
Soeren Christensen Krath
ID:
An Assessment Of Entomological Diversity And The Effect of Organic Coffee Farming on Biodiversity In South Western Uganda Along A National Park Gradient
REFNo: NS66ES

We will go to Bwindi Forest Farm in Uganda to investigate the effects on agroorganic farming. This will be done to analyse what best ways to conserve nature amidst a growing population taking up more space for settlement and agriculture. Here we will look at how effective organic coffee farming is compared to conventional farming in terms of biodiversity seen, incorporation of pollinators and the reduction of coffee's worst enemy, the coffee borer beetle. In this case you will help to support a project where data is collected about renewal of conventional farming into a more agroorganic approach. Project 1 One of our goals is to investigate how well it is to practice organic farming in relation to conventional agriculture as regards to what supports biodiversity best. In relation to this, we will do some specific studies on the entomologi around organic and conventionel coffee plantations as coffee has a huge economic and cultural significance worldwide. This will be done during the dry season running from september till November and during the rainy season running from November til December. Project 2 In this project, we look at one of the coffee plant's biggest enemies, Coffee Borer Beetle, which is a pest that drills into coffee beans and lays eggs in it. These beetles have some enemies, which are parasitoid wasps that naturally fight these pests. Here we will examine whether organic or conventional coffee cultivation is most effective in the natural control of these pests, and in this context where the greatest biodiversity of these wasps occurs. The collection of coffee berries will be done 30 different coffee plants on different conventional and organic farms. This will be done during harvest season of ripe coffee berries in October and as well when the immature green berries show up to see if there are seasonal differences in pest presence. Project 3 In addition, we will look at the effect of organically grown coffee on pollinators of the plant, such as bees, and the conditions that best benefit them. This is done as the number of pollinators worldwide is in decrease, which is a huge problem since pollinationdependent crops, such as the coffee plant, contribute 35 percent of the global crop production volume. This can have a huge impact on the yield and quality of the product, depending on whether it is an organic or conventional farm. This follows the same timeline as project 1.
Denmark 2018-09-24 2021-09-24 Natural Sciences Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
Host Genetic Factors in Pediatric HIV/TB Infections II
REFNo: HS236ES

The cohort development core project of CAfGEN has several unique and innovative features. 1. This project will significantly expand what is currently the largest genomic cohort dedicated to pediatric HIV in Africa. 2. We will prospectively identify and recruit a cohort of HIV-positive, isoniazid naïve children with a strong exposure to TB, but without evidence of active TB disease – such TB resistant individuals are unique and highly desired in the field, even more so among children co-infected with HIV. This approach is highly conducive to high-level genetic mapping and thus has the potential to offer novel molecular insights into the development of active TB disease. 3. The current studies propose the expansion of our genomics studies to Swaziland – a Southern African population that is currently not represented on the African genomics map. This creates long-term opportunities to fulfill the stated desire to make the H3Africa initiative truly pan-African in scope. 4. The network will develop and extend the experience gained and lessons learned in implementing and pursuing genomics education and ethics consultation in furtherance of the mandate of engaging communities in genomics studies, which is key to long-term sustainability.
Uganda 2018-09-24 2021-09-24 Medical and Health Sciences Non-degree Award
Maruthi Sridhar Balaji Bhaskar
ID:
Geospatial Informatics for Environmental and Natural Resource Management
REFNo: PS5ES

Goals and Objectives: The goal of the proposed project is to identify the impact of long-term landscape and environmental changes on the water quality of Lake Victoria. Long-term, continuous remote sensing monitoring data will be utilized to quantify and assess the pigment and nutrient distribution in the waters of Lake Victoria. We hypothesize that the variations in pigment and nutrient concentrations will affect the intensity and spectral characteristics of the water and these relevant spectral signatures can be identified and mapped using satellite remote sensing. The specific objectives are to: 1) Analyze and map the spatial and temporal trends in the water quality characteristics of the Lake Victoria; 2) Identify the best water quality indicators for satellite monitoring of the environmental and ecological changes and 3) Monitor and propose remedial measures for the geographical regions within the Lake which are more vulnerable for the environmental and climate changes.
USA 2018-09-20 2021-09-20 Natural Sciences Non-degree Award
Bosco Bwambale
ID:
Flood risk management under climate and demographic change in Uganda: Evidence from the Nyamwamba
REFNo: A36ES

The study will be guided by three broad objectives: (1) analysis of the factors influencing the severity of flood disasters, (2) identification of flood risk reduction Measures, and (3) determining the most feasible flood risk reduction options for the Rwenzori
Uganda 2018-09-20 2021-09-20 Agricultural Sciences Degree Award
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
Analysis of Routinely Collected Clinical Data to Monitor and Evaluate outcomes of the IDI Kampala-Wakiso region HIV program
REFNo: HS241ES

Primary objective: To describe the entire HIV cascade of care based on the UNAIDS 90:90:90 targets and outcomes of programmatic operational interventions Secondary Objective 1. To characterize the HTC and eMTCT programs and describe their outcomes e.g. lost to follow-up, seroconversion in previously negative mother-baby pairs etc. 2. To characterize the clinical profile of patients enrolled into care, including clinical laboratory indices – CD4, viral load, history of OIs – TB prophylaxis & treatment, ART history; describe their clinical outcomes including poor patient outcomes (drug toxicity, poor adherence, resistance, attrition, IRIS events) 3. To describe uptake of routinely provided prevention strategies, for example: Male medical circumcision (MMC), Prior ART (PrEP, PEP), self-testing; family planning services, sexual behavior risk patterns; (Abstinence, Fidelity, condom use) and their outcomes, e.g. STI’s, new HIV infections, OI’s 4. To describe the quality of routinely collected data - the extent and nature of missing data including data on WHO-UNAIDS required metrics, and accuracy of the electronic record compared to hand-written files 5. To determine the proportion of patients who undergo switching (single drug versus multiple drug), describe the processes of switching and their outcomes (single drug vs multiple drug or regimen switching) or other consequences of regimen adjustments. 6. To describe factors associated with and outcomes of routine approaches to reduce loss to follow up in HIV care of clients who miss appointments or are lost to follow up. 7. To describe the quality, feasibility (including cost-effectiveness) and outcomes of differentiated service delivery strategies (DSS) that are routinely implemented at IDI-supported facilities 8. To describe HIV/TB policy-practice gaps, and routine program strategies used to close these gaps and their outcomes
Uganda 2018-09-18 2021-09-18 Medical and Health Sciences Non-degree Award
Guy Schofield
ID:
Understanding the Ethical Challenges in the Practice of Palliative Care in Uganda
REFNo: SS219ES

Aim: To explore and describe the ethical challenges faced by palliative care professionals in Uganda, and assess clinical and educational implications Objectives: 1) To describe the range of ethical challenges faced by palliative care professionals in Uganda. 2) To explore the normative concepts contained within these challenges. 3) To investigate how these concepts might differ in content across different sub- Saharan Africa countries. 4) To consider the implications of these findings for palliative care professionals and educators in sub-Saharan Africa and worldwide, including the UK. This application relates to objectives 1 & 2.
UK 2018-09-14 2021-09-14 Social Science and Humanities Degree Award
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